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Acknowledgments to reviewers of "International Journal of Occupational Medicine and Environmental Health" in 2023. 致 2023 年 "国际职业医学与环境健康杂志 "审稿人。
IF 2 4区 医学 Q2 Medicine Pub Date : 2024-02-07 DOI: 10.13075/ijomeh.1896.02385
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引用次数: 0
Rehabilitation of sick-listed LBP patients in occupational health with collaboration of the workplace 职业健康部门与工作场所合作,为列入病历的腰椎间盘突出症患者提供康复服务
IF 2 4区 医学 Q2 Medicine Pub Date : 2024-01-25 DOI: 10.13075/ijomeh.1896.02263
Valtteri Kokkonen, A. Lamminpää, Kari Reijula, Fabrizio Russo, Sergio Iavicoli, Vincenzo Denaro, Jaana Kuoppala
The aim was to evaluate if rehabilitation procedures including occupational health (OH) and workplace participation increase return to work (RTW) rates among patients with subacute and chronic low back pain (LBP). A systematic review of randomized controlled trials was conducted using the PubMed and Cochrane databases. Main outcomes were RTW and days of sick leave. Interventions needed to be multidisciplinary including both OH and active workplace involvement in rehabilitation. Out of 1073 potentially eligible references, 8 met the inclusion criteria. Three studies had OH and 5 case managers involved in rehabilitation. Rehabilitation involving both OH and workplace improved RTW and decreased the number of sick leave days among LBP patients. Having case managers involved had no effect in RTW. In order to improve RTW, workplace visits and work ability meetings (WAMs) between OH and workplace are essential components in the rehabilitation process among patients with chronic LBP. Based on the study results, the authors suggest utilizing these co-operative interventions with workplaces in OH. High quality research investigating only the effect of WAMs in OH setting is needed in future. Int J Occup Med Environ Health. 2024;37(1)
该研究旨在评估包括职业健康(OH)和工作场所参与在内的康复程序是否能提高亚急性和慢性腰背痛(LBP)患者的重返工作(RTW)率。我们使用 PubMed 和 Cochrane 数据库对随机对照试验进行了系统性回顾。主要结果为复工率和病假天数。干预措施必须是多学科的,包括 OH 和积极的工作场所康复参与。在 1073 篇可能符合条件的参考文献中,有 8 篇符合纳入标准。其中 3 项研究有医务人员和 5 名个案经理参与康复。由医务人员和工作场所共同参与的康复治疗改善了腰椎间盘突出症患者的复工情况,并减少了病假天数。个案管理者的参与对患者的复工没有影响。为了改善患者的复工情况,在慢性腰椎间盘突出症患者的康复过程中,工作场所探访和工作能力会议(WAMs)是必不可少的组成部分。根据研究结果,作者建议在职业健康中利用这些与工作场所的合作干预措施。今后需要开展高质量的研究,仅调查在职业健康环境中的 WAMs 效果。Int J Occup Med Environ Health.2024;37(1)
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引用次数: 0
Work for the Prison Service: selected health consequences - investigating the role of personal resources, job demands, work stress, and burnout. 监狱服务工作:选定的健康后果——调查个人资源、工作要求、工作压力和倦怠的作用。
IF 2 4区 医学 Q2 Medicine Pub Date : 2023-12-15 Epub Date: 2023-10-23 DOI: 10.13075/ijomeh.1896.02224
Ewa Sygit-Kowalkowska, Katarzyna Orlak, Mikołaj Stolarski

Objectives: The specific job demands of the Prison Service (PS) may affect the health of officers. The job demands-resources model (JD-R) model was used to design a survey of the consequences of working subject to particular job demands. The aim was to gain an insight into the relationship between job demands, personal resources, occupational stress and burnout and selected health consequence indicators (such as behaviors associated with the consumption of alcohol, stress symptoms).

Material and methods: A total of 1732 PS officers in Poland were surveyed. The following tools were used as part of the survey: the Copenhagen Psychosocial Questionnaire (COPSOQ II), the Multidimensional Inventory for Assessing Coping Responses (COPE), the Alcohol Use Disorders Identification Test (AUDIT) and a form with a respondent's particulars. Path analysis using partial least squares structural equation modelling (PLS-SEM) was performed.

Results: The assumed hypotheses were partially confirmed by the results. Out of 4 job demands categories only work pace turned out not to be a significant predictor of burnout and stress. For alcohol related behaviors, stress level was the only significant predictor, both as a direct and indirect effect taking into account job demands. It transpired that support from superiors rather than support from colleagues or self-efficacy was a significant moderator in the emotional demands - stress relationship. Limitations of the study and perspectives for its continuation are also presented herein.

Conclusions: Based on the obtained results it may be concluded that job demands and support from superiors do have an impact on stress in the PS group. This is also consistent with available reports in literature. At the same time stress is a significant predictor of alcohol related behaviors. Coping through the use of psychoactive substances was not a significant factor in statistical analyses and it has still not been subject to sufficient scientific analysis. Int J Occup Med Environ Health. 2023;36(6):744-60.

目的:监狱管理局(PS)的具体工作需求可能会影响官员的健康。工作需求-资源模型(JD-R)用于设计一项调查,调查工作对特定工作需求的影响。目的是深入了解工作需求、个人资源、职业压力和倦怠与选定的健康后果指标(如与饮酒相关的行为、压力症状)之间的关系。材料和方法:共对1732名波兰警察进行了调查。以下工具被用作调查的一部分:哥本哈根心理社会问卷(COPSOQ II)、评估应对反应的多维量表(COPE)、酒精使用障碍识别测试(AUDIT)和一份包含受访者详细信息的表格。使用偏最小二乘结构方程建模(PLS-SEM)进行通径分析。结果:假设的假设被结果部分证实。在4个工作需求类别中,只有工作节奏并不是倦怠和压力的重要预测因素。对于与酒精相关的行为,压力水平是唯一显著的预测因素,考虑到工作需求,压力水平既是直接影响,也是间接影响。研究发现,上级的支持而不是同事的支持或自我效能感是情绪需求-压力关系的重要调节因素。本文还介绍了该研究的局限性和继续研究的前景。结论:根据所获得的结果,可以得出结论,工作需求和上级的支持确实对PS组的压力有影响。这也与文献中现有的报告一致。同时,压力是酒精相关行为的重要预测因素。在统计分析中,通过使用精神活性物质来应对并不是一个重要因素,而且还没有对其进行充分的科学分析。国际神秘医学与环境健康杂志。2023年;36(6)。
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引用次数: 0
Dietary supplements, nutraceuticals and functional foods use after myocardial infarction depend on the age, sex, BMI and professional activity - a pilot study. 心肌梗死后使用的膳食补充剂、营养品和功能性食品取决于年龄、性别、BMI和职业活动——一项试点研究。
IF 2 4区 医学 Q2 Medicine Pub Date : 2023-12-15 Epub Date: 2023-10-09 DOI: 10.13075/ijomeh.1896.02255
Julia Haponiuk-Skwarlińska, Agata Antoniak, Michalina Ciurla, Katarzyna Paluch, Gabriela Makulec, Dominika Klimczak-Tomaniak, Marek Kuch, Maciej Janiszewski

Objectives: To assess dietary supplements, functional foods and nutraceuticals use among the patients after myocardial infarction (MI).

Material and methods: The authors prospectively enrolled 100 consecutive patients hospitalized due to MI and remaining under coordinated outpatient care after MI in the authors' cardiology department.

Results: The authors showed that patients within median (interquartile range) 12.30 (10.18-14.57) months after MI use dietary supplements, nutraceuticals and functional foods in their everyday diet. Vitamins (53% patients), especially vitamin D (35%), were the most frequently used dietary supplements. In contrary to common usage of dietary supplements (59%), smaller proportion of patients use functional foods (21%) and nutraceuticals (5%), especially phytosterols. The authors found that the use of over-the-counter (OTC) drugs and dietary supplements is associated with age (participants <60 years old vs. participants ≥60 years old: OTC drugs: N = 8 [20.0%] vs. N = 32 [53.3%], p < 0.001; herbals: N = 3 [7.5%] vs. N = 16 [26.7%], p = 0.019), sex of the patients following MI (females vs. males: vitamins: N = 17 [70.8%] vs. N = 36 [47,4%], p = 0.045; vitamin D: N = 13 [54.2%] vs. N = 22 [28.9%], p = 0.024; omega-3 fatty acids: N = 3 [12.5%] vs. N = 1 [1.3%], p = 0.042; herbals: N = 8 [33.3%] vs. N = 11[14.5%], p = 0.040), as well as the BMI of the participants (BMI < 24.9 vs. BMI ≥ 25.0: multivitamin/ multimineral dietary supplements: N = 3 [15.0%] vs. N = 31 [42.5%], p = 0.035; vitamin B6: N = 1 [5.0%] vs. N = 21 [28.8%], p = 0.035). In the study group all participants with the age above retirement age have already withdrawn from professional activity and they more often used OTC drugs (N = 14 [25.9%] before retirement age vs. N = 26 [56.5%] above retirement age, p = 0.002).

Conclusions: The patients following MI use supplements, functional foods and nutraceuticals. Their use depends on sex, age, BMI and professional activity. The authors believe that their potential beneficial effects require further evaluation in clinical longitudinal studies. Int J Occup Med Environ Health. 2023;36(6):732-43.

目的:评估心肌梗死(MI)患者的膳食补充剂、功能性食品和营养品的使用情况。材料和方法:作者前瞻性地招募了100名连续因MI住院的患者,并在作者的心脏科对MI后的门诊护理进行协调。结果:作者发现,MI后12.30(10.18-14.57)个月的中位(四分位间距)内的患者在日常饮食中使用膳食补充剂、营养品和功能性食品。维生素(53%的患者),尤其是维生素D(35%),是最常用的膳食补充剂。与膳食补充剂的常见用法(59%)相反,使用功能性食品(21%)和营养品(5%)的患者比例较小,尤其是植物甾醇。作者发现,非处方药和膳食补充剂的使用与年龄有关(参与者6:N=1[5.0%]vs.N=21[28.8%],p=0.035)。在研究组中,所有年龄超过退休年龄的参与者都已经退出了职业活动,他们更经常使用非处方药(N=14[25.9%]在退休年龄前vs。N=26[56.5%]高于退休年龄,p=0.002)。结论:MI患者使用补充剂、功能性食品和营养品。它们的使用取决于性别、年龄、BMI和职业活动。作者认为,它们潜在的有益作用需要在临床纵向研究中进一步评估。国际神秘医学与环境健康杂志。2023年;36(6)。
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引用次数: 0
Time series analysis in environmental epidemiology: challenges and considerations. 环境流行病学中的时间序列分析:挑战和考虑。
IF 2 4区 医学 Q2 Medicine Pub Date : 2023-12-15 Epub Date: 2023-10-02 DOI: 10.13075/ijomeh.1896.02237
Sandra Gudziunaite, Zana Shabani, Lisbeth Weitensfelder, Hanns Moshammer

In environmental epidemiology, time series analyses represent a widely used statistical tool. However, though being commonly used, there is soften confusion regarding the specific requirements, such as which link function might be most appropriate, when or how to control for seasonality or how to account for lags. The present overview draws from experiences in other disciplines and discusses the proper execution of time series analyses based on considerations that are relevant in environmental epidemiology. Time series analysis in environmental epidemiology focuses on acute events caused by short-term changes in exposure. These exposures should be fairly wide-spread affecting a large number of persons, usually all inhabitants of a political entity. Pollutants in air or drinking water as well as meteorological factors serve as typical examples. Despite the many time series analyses performed world-wide, some health effects that would lend themselves to that approach are still under-explored. This would include also some neurological and psychiatric endpoints. Int J Occup Med Environ Health. 2023;36(6):704-16.

在环境流行病学中,时间序列分析是一种广泛使用的统计工具。然而,尽管通常使用,但对于具体要求,如哪种链接功能可能最合适,何时或如何控制季节性,或如何解释滞后,人们的困惑有所缓解。本综述借鉴了其他学科的经验,并讨论了基于环境流行病学相关考虑因素的时间序列分析的正确执行。环境流行病学中的时间序列分析侧重于由暴露的短期变化引起的急性事件。这些暴露应该相当广泛,影响到大量的人,通常是一个政治实体的所有居民。空气或饮用水中的污染物以及气象因素是典型的例子。尽管在世界范围内进行了许多时间序列分析,但这种方法对健康的一些影响仍在探索之中。这也包括一些神经和精神方面的终点。国际神秘医学与环境健康杂志。2023年;36(6)。
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引用次数: 0
Factors influencing the mental health status of support nurses and their workload during the COVID-19 epidemic. COVID-19疫情期间支持护士心理健康状况及工作量的影响因素
IF 2 4区 医学 Q2 Medicine Pub Date : 2023-12-15 Epub Date: 2023-11-30 DOI: 10.13075/ijomeh.1896.02155
Zhen-Juan Dai, Shen-Ting Xu, Fang-Ying Xue, Jian-Ying Zhou, Jian-Qin Chen, Xue-Min Wang

Objectives: The authors used the National Aeronautics and Space Administration Task Load Index (NASA-TLX) and general health questionnaire to analyze the factors influencing the mental health status and the workload of support nurses during the COVID-19 epidemic.

Material and methods: The authors conducted a cross-sectional survey of 349 support nurses in April-October 2022. Using QuestionStar, a powerful online survey tool, the authors administered surveys to the participants, collected data on the mental health status and workload of support nurses, and analyzed the influencing factors based on the collected data.

Results: A total of 316 questionnaires were successfully collected, with an effective rate of 98.75%. The proportion of support nurses with mental health problems was 25% and the value of the NASA-TLX questionnaire was: M±SD 68.91±7.28 pts. Multi-factor analysis revealed that the number of children, family support, and nursing support location were the influencing factors of mental health status, while the multivariate analysis revealed that the presence of symptoms, nursing support location, support work type, and total 12-item General Health Questionnaire (GHQ-12) score were the influencing factors of the workload of support nurses.

Conclusions: Compared to their counterparts in the plains, nurses working in isolated plateau regions who were caring for children and lacked family support, were more likely to have mental health issues. There was a positive correlation between the changes in GHQ-12 and NASA-TLX scores of the study participants. Compared to their counterparts in the plains and the tropical regions, nurses working in plateau regions had a heavier workload. As part of the follow-up measures to prevent and treat patients impacted by the COVID-19 epidemic, it is important to improve the mental health evaluation, consultation, and treatment of the support nurses to guarantee the high quality of the first-line support work. Int J Occup Med Environ Health. 2023;36(6)761-72.

目的:采用nasa任务负荷指数(NASA-TLX)和一般健康问卷,分析新型冠状病毒肺炎疫情期间保障护士心理健康状况和工作量的影响因素。材料与方法:作者于2022年4 - 10月对349名支持护士进行横断面调查。利用强大的在线调查工具QuestionStar对参与者进行问卷调查,收集支持护士的心理健康状况和工作量数据,并根据收集到的数据分析影响因素。结果:共回收问卷316份,有效回收率为98.75%。支持护士有心理健康问题的比例为25%,NASA-TLX问卷值为:M±SD(68.91±7.28)分。多因素分析显示,子女数量、家庭支持和护理支持地点是影响心理健康状况的因素,多因素分析显示,症状存在、护理支持地点、支持工作类型和12项一般健康问卷(GHQ-12)总分是影响支持护士工作量的因素。结论:与平原地区的护士相比,在偏远高原地区工作的护士在照顾儿童和缺乏家庭支持的情况下,更容易出现心理健康问题。研究参与者GHQ-12的变化与NASA-TLX评分之间存在正相关。与平原和热带地区相比,高原地区护士的工作量更大。做好对支持护士的心理健康评估、咨询和治疗工作,是防控受新冠肺炎疫情影响患者的后续措施之一,是保障一线支持工作高质量的重要保障。中华医学杂志,2009;36(6)。
{"title":"Factors influencing the mental health status of support nurses and their workload during the COVID-19 epidemic.","authors":"Zhen-Juan Dai, Shen-Ting Xu, Fang-Ying Xue, Jian-Ying Zhou, Jian-Qin Chen, Xue-Min Wang","doi":"10.13075/ijomeh.1896.02155","DOIUrl":"10.13075/ijomeh.1896.02155","url":null,"abstract":"<p><strong>Objectives: </strong>The authors used the <i>National Aeronautics and Space Administration Task Load Index</i> (NASA-TLX) and general health questionnaire to analyze the factors influencing the mental health status and the workload of support nurses during the COVID-19 epidemic.</p><p><strong>Material and methods: </strong>The authors conducted a cross-sectional survey of 349 support nurses in April-October 2022. Using QuestionStar, a powerful online survey tool, the authors administered surveys to the participants, collected data on the mental health status and workload of support nurses, and analyzed the influencing factors based on the collected data.</p><p><strong>Results: </strong>A total of 316 questionnaires were successfully collected, with an effective rate of 98.75%. The proportion of support nurses with mental health problems was 25% and the value of the NASA-TLX questionnaire was: M±SD 68.91±7.28 pts. Multi-factor analysis revealed that the number of children, family support, and nursing support location were the influencing factors of mental health status, while the multivariate analysis revealed that the presence of symptoms, nursing support location, support work type, and total 12-item <i>General Health Questionnaire</i> (GHQ-12) score were the influencing factors of the workload of support nurses.</p><p><strong>Conclusions: </strong>Compared to their counterparts in the plains, nurses working in isolated plateau regions who were caring for children and lacked family support, were more likely to have mental health issues. There was a positive correlation between the changes in GHQ-12 and NASA-TLX scores of the study participants. Compared to their counterparts in the plains and the tropical regions, nurses working in plateau regions had a heavier workload. As part of the follow-up measures to prevent and treat patients impacted by the COVID-19 epidemic, it is important to improve the mental health evaluation, consultation, and treatment of the support nurses to guarantee the high quality of the first-line support work. Int J Occup Med Environ Health. 2023;36(6)761-72.</p>","PeriodicalId":14173,"journal":{"name":"International journal of occupational medicine and environmental health","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10743344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138459870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current incidence of professional burnout among Ukrainian oncologists in Kharkiv. 哈尔科夫乌克兰肿瘤学家职业倦怠的现状。
IF 2 4区 医学 Q2 Medicine Pub Date : 2023-12-15 Epub Date: 2023-10-10 DOI: 10.13075/ijomeh.1896.02244
Irina Böckelmann, Igor Zavgorodnij, Olena Litovchenko, Valerij Kapustnyk, Mykola Krasnoselskyi, Kseniia Zub, Ulrike Woitha, Cecile Gonschor, Beatrice Thielmann

Objectives: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic and the military conflicts in Ukraine suggest that workrelated stressors increased during these crises increases work-related stress reactions. Burnout as a long-term consequence of insufficiently compensated for workloads. The regional prevalence of burnout is particularly high among oncologists. The aim of this study was to assess the current risk of burnout within this group of physicians and to examine gender differences through gender-based analysis.

Material and methods: Thirtyseven oncologists (17 men and 20 women aged 46.5±13.6 years [range 26-74 years]) in Kharkiv, Ukraine, participated. The Maslach Burnout Inventory - General Survey (MBI-GS) questionnaire was used to determine the extent of occupational.

Results: Gender, age, and work experience had no effect on the following results. Women demonstrated higher scores in emotional exhaustion and personal accomplishment of the MBI than men. In contrast, men offered higher cynicism scores. The MBI total score was also higher for the male oncologists. Only 1 person of the total sample had risk of burnout.

Conclusions: The results showed a high prevalence of burnout symptoms among Ukrainian oncologists without gender differences. From occupational health perspective behavioral and behavior-preventive measures are needed for clinics and oncologists to counteract the burnout symptoms, e.g. exhaustion or cyniscism. Further studies are needed here to examine the effectiveness of these measures. Int J Occup Med Environ Health. 2023;36(6):717-3.

目的:严重急性呼吸系统综合征冠状病毒2型(SARS-CoV-2)大流行和乌克兰的军事冲突表明,在这些危机期间,与工作相关的压力源增加,增加了与工作有关的压力反应。由于工作量补偿不足而导致的长期倦怠。肿瘤科医生职业倦怠的地区流行率特别高。本研究的目的是评估这组医生目前的倦怠风险,并通过基于性别的分析来检验性别差异。材料和方法:乌克兰哈尔科夫的37名肿瘤学家(17名男性和20名女性,年龄46.5±13.6岁[范围26-74岁])参加了研究。Maslach倦怠量表-综合调查(MBI-GS)问卷用于确定职业程度。结果:性别、年龄和工作经验对以下结果没有影响。女性在情感耗竭和MBI个人成就方面的得分高于男性。相比之下,男性的冷嘲热讽得分更高。男性肿瘤学家的MBI总分也较高。总样本中只有1人有倦怠的风险。结论:研究结果显示,在没有性别差异的乌克兰肿瘤学家中,倦怠症状的发生率很高。从职业健康的角度来看,诊所和肿瘤学家需要采取行为和行为预防措施来对抗倦怠症状,如疲劳或食蟹癖。这里需要进一步的研究来检验这些措施的有效性。国际神秘医学与环境健康杂志。2023年;36(6)。
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引用次数: 0
Construction and validation of the Areas of Academic Life Scale to measure organizational risk factors for student burnout. 学业生活领域量表测量学生职业倦怠的组织风险因素的构建与验证。
IF 2 4区 医学 Q2 Medicine Pub Date : 2023-12-15 Epub Date: 2023-11-22 DOI: 10.13075/ijomeh.1896.02173
Teresa Chirkowska-Smolak, Magdalena Piorunek, Żaneta Garbacik

Objectives: Academic burnout poses a challenge to the educational process. Higher education institutions have responsibilities similar to the ones of management in business settings. These institutions are responsible for creating conditions conducive to development and, as such, may be interested in verifying the presence of student burnout and pinpointing its causes. The purpose of this study was to answer these needs and develop a scale to measure the effect of organizational factors that may predict student burnout.

Material and methods: This paper reports the results of a study conducted on a sample of Polish students (N = 659) to construct and validate a multidimensional measure of organizational factors impacting academic burnout, focusing on students. For background purposes and as a starting point, the authors used the concept of the areas of worklife by Ch. Maslach and M. Leiter, who identified 6 areas of the work environment that affect the relationships people develop with their work, i.e., workload, control, reward, community, fairness, and values.

Results: The authors assessed the factor structure, reliability, and construct validity and performed confirmatory factor analysis of the new scale to measure 6 areas of academic life. Given the results of this study, the scale can be recommended as an adequate tool to measure organizational (academic) factors of burnout in students.

Conclusions: The authors have validated the final scale, which can be used to advance the understanding of the academic burnout phenomenon. Int J Occup Med Environ Health. 2023;36(6):798-811.

目的:学业倦怠对教育过程提出了挑战。高等教育机构的责任类似于商业环境中的管理。这些机构有责任创造有利于发展的条件,因此,可能有兴趣核实学生倦怠的存在并查明其原因。本研究的目的是回答这些需求,并制定一个量表来衡量组织因素对学生倦怠的影响。材料与方法:本文报告了一项以波兰学生(N = 659)为样本的研究结果,以学生为中心,构建并验证了影响学业倦怠的组织因素的多维测量。作为背景和起点,我们使用了Ch. Maslach和M. Leiter的工作生活领域的概念,他们确定了影响人们与工作发展关系的工作环境的6个领域,即工作量,控制,奖励,社区,公平和价值观。结果:作者对新量表的因子结构、信度、构建效度进行了评估,并进行了验证性因子分析,测量了学业生活的6个方面。鉴于本研究的结果,我们可以推荐该量表作为衡量学生职业倦怠的组织(学业)因素的适当工具。结论:我们已对最终量表进行了验证,该量表可用于促进对学业倦怠现象的认识。中华医学杂志,2009;36(6)。
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引用次数: 0
The impact of dietary nitrates and acrylamide intake on systemic redox status in healthy young adults. 膳食硝酸盐和丙烯酰胺摄入量对健康年轻人全身氧化还原状态的影响
IF 2 4区 医学 Q2 Medicine Pub Date : 2023-12-15 Epub Date: 2023-11-22 DOI: 10.13075/ijomeh.1896.02246
Agnieszka Piwowar, Ewa Żurawska-Płaksej, Anna Bizoń, Ewa Sawicka, Sylwia Płaczkowska, Anna Prescha

Objectives: The nitrogen-containing xenobiotics, such as nitrates and acrylamide may potentially influence systemic redox status and contribute to the generation of oxidative stress (OS) in the human body, but there is still a lack of studies that would evaluate the various parameters assessing the oxidative-antioxidant balance. The aim of this study was to evaluate the exposure to nitrates and acrylamide derived from daily diet and to analyze the impact of these nitrate-containing xenobiotics on the parameters of systemic redox status in healthy young adults.

Material and methods: To assess nitrate and acrylamide intake in the study population, a semi-quantitative food frequency questionnaire was used. Systemic redox status was evaluated by measurement of a panel of biochemical parameters: enzymatic (glutathione S-transferase, glutathione reductase, glutathione peroxidase [GPx]) and non-enzymatic (uric acid, bilirubin and albumin), thiol/disulphide homeostasis parameters (total thiol, native thiol, and disulfide) and oxidative/ antioxidant balance indicators (total antioxidant status, total oxidant status, OS index).

Results: The average consumption of nitrates and acrylamide in the study population was 1.24 mg/kg b.w./day and 0.23 μg/kg b.w./day, respectively, which is within the normal value range. Of 12 measured parameters, significant differences were revealed for disulfide and total thiol levels, which were increased in the subgroup with the highest daily intake of nitrates compared to the subgroup with the lowest intake; for GPx, which was highest in the subgroup of the lowest daily intake of acrylamide; and for native thiols in the subgroup with the highest daily intake.

Conclusions: The intake of nitrogen-containing xenobiotics within the range considered as normal does not markedly influence redox state parameters in healthy young adults. Some significant changes were revealed only for thiol/disulphide homeostasis parameters, which may be the first line of antioxidant defense, as well as for GPx activity. Compensative mechanisms in healthy young people are efficient enough to neutralize OS induced by slightly increased exposure to nitrogen-containing xenobiotics delivered with food. Int J Occup Med Environ Health. 2023;36(6):773-87.

目的:含氮的异种生物,如硝酸盐和丙烯酰胺,可能会潜在地影响人体的系统氧化还原状态,并有助于氧化应激(OS)的产生,但仍然缺乏评估评估氧化-抗氧化平衡的各种参数的研究。本研究的目的是评估日常饮食中硝酸盐和丙烯酰胺的暴露情况,并分析这些含硝酸盐的外源物对健康年轻人全身氧化还原状态参数的影响。材料与方法:采用半定量食物频率问卷法评估研究人群中硝酸盐和丙烯酰胺的摄入量。通过测量一组生化参数来评估系统氧化还原状态:酶促(谷胱甘肽s转移酶、谷胱甘肽还原酶、谷胱甘肽过氧化物酶[GPx])和非酶促(尿酸、胆红素和白蛋白)、硫醇/二硫稳态参数(总硫醇、天然硫醇和二硫)和氧化/抗氧化平衡指标(总抗氧化状态、总氧化状态、OS指数)。结果:研究人群硝酸盐和丙烯酰胺的平均摄入量分别为1.24 mg/kg b.w./d和0.23 mg/kg b.w./d,在正常值范围内。在12个测量参数中,发现二硫化物和总硫醇水平存在显著差异,每日硝酸盐摄入量最高的亚组与摄入量最低的亚组相比,二硫化物和总硫醇水平有所增加;丙烯酰胺日摄入量最低亚组中GPx含量最高;对于每日摄入量最高的亚组中的天然硫醇。结论:在正常范围内摄入含氮异种生物制剂对健康青年氧化还原状态参数无显著影响。只有硫醇/二硫化物稳态参数(可能是抗氧化防御的第一道防线)和GPx活性发生了显著变化。健康年轻人的代偿机制足够有效,可以中和因食物中含氮异种抗生素的少量增加而引起的OS。中华医学杂志,2009;36(6)。
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引用次数: 0
The relationship between working time mismatch and depression according to actual hours worked. 根据实际工作时数,研究工作时间错配与抑郁的关系。
IF 2 4区 医学 Q2 Medicine Pub Date : 2023-12-15 Epub Date: 2023-11-30 DOI: 10.13075/ijomeh.1896.02145
Ji Ho Kim, Shin Goo Park, Hwan Cheol Kim, Sang Hee Hwang

Objectives: The effect of the combination of working hours and working time mismatch on depression is unknown. This study was undertaken to confirm the relationship between working time mismatch and depression with respect to hours worked.

Material and methods: The data of 45 514 adult workers that participated in the 6th Korean Working Conditions Survey (KWCS-VI 2020) were reviewed. Depression was defined using the World Health Organization 5 Well-Being Index (WHO-5) cut-off score of 50. Working time mismatch was defined as a difference between actual and desired working hours. To identify associations between working hour mismatch and depression according to weekly hours worked, stratification analysis was conducted by dividing the study subjects into 3 groups based on actual hours worked weekly (<40 h, 40-<52 h, or ≥52 h). Multiple logistic regression analysis adjusted for potential confounders was performed to calculate odds ratios of depression.

Results: In the <40 h, 40-<52 h, and ≥52 h groups, the odds ratios (OR) of working more hours than desired were 1.51, 95% CI: 1.20-1.92 (<40 h), 1.70, 95% CI: 1.58-1.84 (40-<52 h), and 1.55, 95% CI: 1.41-1.69 (≥52 h), respectively, compared to a matched actual versus desired working hours group (the matched group). On the other hand, the odds ratios of working fewer hours than desired were 1.17, 95% CI: 1.07-1.27 (<40 h), 1.38, 95% CI: 1.20-1.60 (40-<52 h), and 1.98, 95% CI: 1.24-3.17 (≥52 h), respectively. The risk of depression was found to increase significantly with working time mismatch within all 3 working hour groups.

Conclusions: Working time mismatch increases the risk of worker depression regardless of hours worked. Int J Occup Med Environ Health. 2023;36(6):788-97.

目的:尚不清楚工作时间组合和工作时间不匹配对抑郁症的影响。本研究旨在确认工作时间不匹配与抑郁之间的关系。材料与方法:对参加第六次韩国劳动条件调查(KWCS-VI 2020)的45 514名成年劳动者的数据进行分析。抑郁症的定义采用世界卫生组织5幸福指数(WHO-5) 50分的临界值。工作时间不匹配被定义为实际工作时间与期望工作时间之间的差异。为了确定每周工作时间错配与抑郁之间的关系,我们将研究对象按每周实际工作时间分成3组进行分层分析(结果:在结论中:无论工作时间长短,工作时间错配都增加了员工抑郁的风险。中华医学杂志,2009;36(6)。
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International journal of occupational medicine and environmental health
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