{"title":"Preparation and Characterization of Mucoadhesive Proniosomal Gel of Curcumin with Thiolated Chitosan for the Treatment of Oral Mucositis","authors":"S. Vashist, M. Gadewar","doi":"10.5530/ijpi.13.3.083","DOIUrl":"https://doi.org/10.5530/ijpi.13.3.083","url":null,"abstract":"","PeriodicalId":14218,"journal":{"name":"International Journal of Pharmaceutical Investigation","volume":"50 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74301544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stability Indicating HPTLC Method Development and Validation for Quantification of Favipiravir in Bulk and Commercial Film Coated Tablet","authors":"A. Balap, Aniket Padmakant Dudhe","doi":"10.5530/ijpi.13.3.071","DOIUrl":"https://doi.org/10.5530/ijpi.13.3.071","url":null,"abstract":"","PeriodicalId":14218,"journal":{"name":"International Journal of Pharmaceutical Investigation","volume":"5 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81776794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Subhashchandra K. Patel, Hirenkumar R. Chaudhary, T. Gandhi
{"title":"Design, Optimization and Characterization of Newer Herbal Tablet Containing Momordica dioica Extract","authors":"Subhashchandra K. Patel, Hirenkumar R. Chaudhary, T. Gandhi","doi":"10.5530/ijpi.13.3.067","DOIUrl":"https://doi.org/10.5530/ijpi.13.3.067","url":null,"abstract":"","PeriodicalId":14218,"journal":{"name":"International Journal of Pharmaceutical Investigation","volume":"28 5 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85543404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad Abid Mustafa, Asad Majeed Khan, N. Ali, F. Ahmed, M. Latif, Zukhruf Shahid, Minahil Akram, A. Ijaz, Minahil Arif, Ahmad Ilyas, Maria Asghar, Mahgull Mahmood, Tameen Amin
{"title":"Formulation and in vitro Evaluation of pH Dependent Colon Targeted Controlled Release Tablet of Mesalamine Containing Cyamopsis tetragonoloba Gum and Sodium Alginate","authors":"Muhammad Abid Mustafa, Asad Majeed Khan, N. Ali, F. Ahmed, M. Latif, Zukhruf Shahid, Minahil Akram, A. Ijaz, Minahil Arif, Ahmad Ilyas, Maria Asghar, Mahgull Mahmood, Tameen Amin","doi":"10.5530/ijpi.13.3.059","DOIUrl":"https://doi.org/10.5530/ijpi.13.3.059","url":null,"abstract":"","PeriodicalId":14218,"journal":{"name":"International Journal of Pharmaceutical Investigation","volume":"71 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82211869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Drug Utilization Evaluation of Antidiabetic Drugs in a Tertiary Care Teaching Hospital: Analysis from a Randomized Controlled Study","authors":"Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Vishwanatha Swamy, Bharati Kangrali","doi":"10.5530/ijpi.13.3.084","DOIUrl":"https://doi.org/10.5530/ijpi.13.3.084","url":null,"abstract":"","PeriodicalId":14218,"journal":{"name":"International Journal of Pharmaceutical Investigation","volume":"42 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90452624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Uppara Veerendra, P. A. Basha, Byragani Naga Bindu, Deti Pruthvi Bhushan, Gutam Venkata Kalyani
{"title":"Prevalence of Musculoskeletal Disorders and Health Related Quality of Life (HRQoL) in Patients Visiting Secondary Healthcare Setting","authors":"Uppara Veerendra, P. A. Basha, Byragani Naga Bindu, Deti Pruthvi Bhushan, Gutam Venkata Kalyani","doi":"10.5530/ijpi.13.3.078","DOIUrl":"https://doi.org/10.5530/ijpi.13.3.078","url":null,"abstract":"","PeriodicalId":14218,"journal":{"name":"International Journal of Pharmaceutical Investigation","volume":"24 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83044192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Overview on Evolving Variants of Novel Coronavirus and Control Measures in India","authors":"P. P., Jeyasree M G, S. R","doi":"10.5530/ijpi.13.3.048","DOIUrl":"https://doi.org/10.5530/ijpi.13.3.048","url":null,"abstract":"","PeriodicalId":14218,"journal":{"name":"International Journal of Pharmaceutical Investigation","volume":"60 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83923295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Formulation, Development and Characterization of Liposome-based Gel of Eberconazole Nitrate for Topical Delivery","authors":"N. Shah, K. Patel","doi":"10.5530/ijpi.13.3.060","DOIUrl":"https://doi.org/10.5530/ijpi.13.3.060","url":null,"abstract":"","PeriodicalId":14218,"journal":{"name":"International Journal of Pharmaceutical Investigation","volume":"15 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84746752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Glara Anest Francis, Sureka Arumugam, Sabari Girija Navaneetha Krishnan, R. Murugan, Christian Gnanaraj Johnson, Moses Erin Johnson Christian, Meenakumari Ramasamy
Introduction: Ovarian cancer is the fifth most common cause of cancer which causes more deaths than any other cancer of the female reproductive system because there is no effective screening and most women are diagnosed at advanced stages. The probability of survival at 5 years is less than 30%, and the limitation is that it will not respond to chemotherapy protocol and surgery as well. Nandhi mezhugu is a Siddha herbo-mineral drug widely used to treat cancer. Hence, the present study was intended to evaluate the anti-cancer activity of Nandhi mezhugu on (PA-1) cell line through MTT assay. Materials and Methods: Stock solutions were prepared from the formulation at various concentrations with serial dilution. Compared with the control and Methotrexate, the extracts were tested using MTT assay at different concentrations. Results: This study substantiated that the percentage of cell viability of cell line viability decrease with increase in concentration of the test drug NM. Least viability of cell was observed at the concentration of 200µg/mL was 73.02 ± 4.584%, followed by this at 100 µg and 50 µg shows 82.36 ± 3.084%, 87.81 ± 2.657, similarly 10 µg/mL shows 95.89 ± 1.054% cell viability in MTT assay. Conclusion: Thus, the current study brings forth scientific evidence for the efficacy of Nandhi mezhugu against the ovarian cancer (PA1) cell line.
{"title":"In vitro Anti-cancer Activity of Nandhi mezhugu (NM) in Ovarian Cancer Cell Line (PA-1) Using MTT Assay","authors":"Glara Anest Francis, Sureka Arumugam, Sabari Girija Navaneetha Krishnan, R. Murugan, Christian Gnanaraj Johnson, Moses Erin Johnson Christian, Meenakumari Ramasamy","doi":"10.5530/ijpi.13.3.080","DOIUrl":"https://doi.org/10.5530/ijpi.13.3.080","url":null,"abstract":"Introduction: Ovarian cancer is the fifth most common cause of cancer which causes more deaths than any other cancer of the female reproductive system because there is no effective screening and most women are diagnosed at advanced stages. The probability of survival at 5 years is less than 30%, and the limitation is that it will not respond to chemotherapy protocol and surgery as well. Nandhi mezhugu is a Siddha herbo-mineral drug widely used to treat cancer. Hence, the present study was intended to evaluate the anti-cancer activity of Nandhi mezhugu on (PA-1) cell line through MTT assay. Materials and Methods: Stock solutions were prepared from the formulation at various concentrations with serial dilution. Compared with the control and Methotrexate, the extracts were tested using MTT assay at different concentrations. Results: This study substantiated that the percentage of cell viability of cell line viability decrease with increase in concentration of the test drug NM. Least viability of cell was observed at the concentration of 200µg/mL was 73.02 ± 4.584%, followed by this at 100 µg and 50 µg shows 82.36 ± 3.084%, 87.81 ± 2.657, similarly 10 µg/mL shows 95.89 ± 1.054% cell viability in MTT assay. Conclusion: Thus, the current study brings forth scientific evidence for the efficacy of Nandhi mezhugu against the ovarian cancer (PA1) cell line.","PeriodicalId":14218,"journal":{"name":"International Journal of Pharmaceutical Investigation","volume":"25 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82840823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analytical Method Development and Validation for Determination of Valganciclovir by Using RP-HPLC","authors":"Gaddam Venkata Abhigna, R. Sundararajan","doi":"10.5530/ijpi.13.3.076","DOIUrl":"https://doi.org/10.5530/ijpi.13.3.076","url":null,"abstract":"","PeriodicalId":14218,"journal":{"name":"International Journal of Pharmaceutical Investigation","volume":"47 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77107045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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