Pub Date : 2022-10-25DOI: 10.5348/100063z11ts2022cr
Tsuyoshi Saito, Daisuke Kubota, Keita Sasa, Nobuhiko Hasegawa, T. Hayashi, T. Takagi, M. Ishijima
Introduction: Microcystic/reticular schwannoma is a distinctive histopathological variant of schwannoma, which is rare. Its occurrence in the subcutaneous soft tissue of the lower extremity has rarely been reported. Case Report: We report a microcystic/reticular schwannoma arising from a subcutaneous lesion on the lower leg of a 33-year-old man. The patient noticed a subcutaneous mass on the right lower leg six months before admission and experienced radiation pain in the left lower leg. Magnetic resonance imaging revealed a well-demarcated mass with 11-mm maximum diameter with low signal intensity on T1-weighted imaging and high signal intensity on T2-weighted imaging in the subcutaneous region of the right lower leg. Histological examination revealed a cellular area at the periphery of the tumor, although the majority of the tumor showed a microcystic/reticular structure within the myxo-collagenous stroma. The current case was well capsulated and did not show an infiltrative growth pattern. In addition, aggregation of foamy macrophages was frequently seen, although it was reported as a rare feature. After complete surgical excision with clean resection margins, the patient is well, with no evidence of tumor recurrence on follow-up after postoperative 14 months. Conclusion: In this case, infrequent findings for microcystic/reticular schwannoma were observed, although the presence of the classical Antoni A area was helpful for the diagnosis of microcystic/reticular schwannoma.
微囊性/网状神经鞘瘤是神经鞘瘤的一种独特的组织病理学变异，非常罕见。它发生在下肢皮下软组织很少被报道。病例报告:我们报告一个微囊/网状神经鞘瘤产生于皮下病变的小腿，33岁的男性。患者入院前6个月发现右下肢皮下肿块，左下肢放射痛。mri示右小腿皮下一清晰肿块，最大直径11 mm, t1低信号，t2高信号。组织学检查显示肿瘤周围有一个细胞区，尽管大多数肿瘤在黏液-胶原基质内表现为微囊/网状结构。目前的病例包膜良好，没有表现出浸润性生长模式。此外，泡沫状巨噬细胞聚集是常见的，尽管这是一种罕见的特征。手术切除完整，切除边缘干净，患者情况良好，术后14个月随访无肿瘤复发迹象。结论:尽管经典Antoni A区有助于微囊/网状神经鞘瘤的诊断，但本病例微囊/网状神经鞘瘤的少见表现。
{"title":"Microcystic/reticular schwannoma of the lower leg: Case report with review of literature","authors":"Tsuyoshi Saito, Daisuke Kubota, Keita Sasa, Nobuhiko Hasegawa, T. Hayashi, T. Takagi, M. Ishijima","doi":"10.5348/100063z11ts2022cr","DOIUrl":"https://doi.org/10.5348/100063z11ts2022cr","url":null,"abstract":"\u0000 Introduction: Microcystic/reticular schwannoma is a distinctive histopathological variant of schwannoma, which is rare. Its occurrence in the subcutaneous soft tissue of the lower extremity has rarely been reported.\u0000\u0000 Case Report: We report a microcystic/reticular schwannoma arising from a subcutaneous lesion on the lower leg of a 33-year-old man. The patient noticed a subcutaneous mass on the right lower leg six months before admission and experienced radiation pain in the left lower leg. Magnetic resonance imaging revealed a well-demarcated mass with 11-mm maximum diameter with low signal intensity on T1-weighted imaging and high signal intensity on T2-weighted imaging in the subcutaneous region of the right lower leg. Histological examination revealed a cellular area at the periphery of the tumor, although the majority of the tumor showed a microcystic/reticular structure within the myxo-collagenous stroma. The current case was well capsulated and did not show an infiltrative growth pattern. In addition, aggregation of foamy macrophages was frequently seen, although it was reported as a rare feature. After complete surgical excision with clean resection margins, the patient is well, with no evidence of tumor recurrence on follow-up after postoperative 14 months.\u0000\u0000 Conclusion: In this case, infrequent findings for microcystic/reticular schwannoma were observed, although the presence of the classical Antoni A area was helpful for the diagnosis of microcystic/reticular schwannoma.\u0000","PeriodicalId":142535,"journal":{"name":"Journal of Case Reports and Images in Pathology","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126747293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5348/100070z11ao2023cr
A. Ouédraogo, W. N. Ramdé, F. Ido, I. Savadogo, R. A. Ouédraogo, S. Ouattara, Aïda S Ouedraogo, Wyc Nikiema
Introduction: Myocardial steatosis, a poorly documented pathology, is characterized by the accumulation of abnormal amounts of triglycerides in the cardiomyocytes. Myocardial steatosis is generally asymptomatic, but it can be the cause of heart failure. It is primarily of hypoxic or metabolic origin. Case Report: We report a case of postmortem diagnosis in a 53-year-old male patient, without known his pathological history, who was a victim of sudden death from abdominal pain. The autopsy revealed diffuse atheromatous cardiac, aortic, and hepatic lesions. Conclusion: It is very common for myocardial steatosis to be diagnosed postmortem due to its nonspecific symptomatology. The risk of mortality and morbidity could be reduced through a healthy lifestyle and regular biological examination to identify risk factors.
{"title":"Myocardial steatosis: An autopsy-discovered case","authors":"A. Ouédraogo, W. N. Ramdé, F. Ido, I. Savadogo, R. A. Ouédraogo, S. Ouattara, Aïda S Ouedraogo, Wyc Nikiema","doi":"10.5348/100070z11ao2023cr","DOIUrl":"https://doi.org/10.5348/100070z11ao2023cr","url":null,"abstract":"\u0000 Introduction: Myocardial steatosis, a poorly documented pathology, is characterized by the accumulation of abnormal amounts of triglycerides in the cardiomyocytes. Myocardial steatosis is generally asymptomatic, but it can be the cause of heart failure. It is primarily of hypoxic or metabolic origin.\u0000\u0000 Case Report: We report a case of postmortem diagnosis in a 53-year-old male patient, without known his pathological history, who was a victim of sudden death from abdominal pain. The autopsy revealed diffuse atheromatous cardiac, aortic, and hepatic lesions.\u0000\u0000 Conclusion: It is very common for myocardial steatosis to be diagnosed postmortem due to its nonspecific symptomatology. The risk of mortality and morbidity could be reduced through a healthy lifestyle and regular biological examination to identify risk factors.\u0000","PeriodicalId":142535,"journal":{"name":"Journal of Case Reports and Images in Pathology","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125410525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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