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TAVR for Severe Aortic Valve Stenosis with LVOT Stenosis: A Case Report. 重度主动脉瓣狭窄伴左心室出口狭窄的 TAVR 治疗:病例报告。
IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-29 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S456154
Qing Zhang, Yao Xu, Hao Wang, Xuelian Pang, Qingfeng Meng

Transcatheter aortic valve replacement (TAVR) has been recently indicated for the treatment of patients with severe aortic stenosis in all risk profiles. At present, TAVR has become mature at home and abroad, but the relevant experience is deficient in the treatment of aortic valve stenosis with outflow tract stenosis. One case of a high-risk surgical patient was included in this paper who suffered from severe aortic valve stenosis with left ventricular outflow tract (LVOT) stenosis. In this case, TAVR was performed with deep implantation of a new valve and both aortic valve stenosis and LVOT stenosis were treated through a single TAVR procedure. This case highlights the vital role of such treatment in dealing with both aortic valve stenosis and LVOT stenosis through a single TAVR procedure, thus providing valuable information for similar cases.

经导管主动脉瓣置换术(TAVR)最近已被用于治疗各种风险情况下的重度主动脉瓣狭窄患者。目前,经导管主动脉瓣置换术在国内外已趋于成熟,但在治疗伴有流出道狭窄的主动脉瓣狭窄方面,相关经验尚显不足。本文收录的一例高危手术患者患有严重的主动脉瓣狭窄合并左室流出道(LVOT)狭窄。在该病例中,通过一次 TAVR 手术治疗了主动脉瓣狭窄和左心室流出道狭窄。该病例强调了通过一次 TAVR 手术同时治疗主动脉瓣狭窄和左心室出口狭窄的重要作用,从而为类似病例提供了有价值的信息。
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引用次数: 0
Vim-PSA Double-Target DBS for the Treatment of Holmes Tremor Secondary to Brainstem Hemorrhage: A Case Report. Vim-PSA 双靶点脊髓束缚治疗继发于脑干出血的霍姆斯震颤:病例报告。
IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-24 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S469937
Zonglei Chong, Xiaoqian Yang, Xiaoxiao Peng, Qiang Zong, Hongxing Li, Yilei Xiao

We report the case of a 53-year-old man who was diagnosed with Holmes tremor and underwent deep brain stimulation of the ventro-intermediate thalamic nucleus and posterior subthalamic area. We assessed the patients' tremor with the Fahn-Tolosa-Marin Tremor Rating Scale at 1, 3, 6, 12 and 24 months after deep brain stimulation. Deep brain stimulation relieved the patient's tremor during the 24-month follow-up period.

我们报告了一例 53 岁男子的病例,他被诊断患有霍姆斯震颤,并接受了丘脑腹中核和丘脑后丘脑下区的深部脑刺激。我们在深部脑刺激术后 1、3、6、12 和 24 个月使用 Fahn-Tolosa-Marin 震颤评分量表评估了患者的震颤情况。在 24 个月的随访期间,深部脑刺激缓解了患者的震颤。
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引用次数: 0
Recurrent Posterior Capsular Opacification in Adults: A Case Report and an Overview of Literature. 成人复发性后囊翳:病例报告和文献综述。
IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-23 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S476559
Majid Moshirfar, Alex H Brown, Garrett N Manion, Kayvon A Moin, Phillip C Hoopes

Posterior capsular opacification (PCO), also known as "secondary cataract", is a common complication following cataract surgery that can significantly impair visual acuity. The incidence of PCO varies widely in the literature, influenced by intraocular lens (IOL) type and patient risk factors. Neodymium-doped yttrium-aluminum-garnet (YAG) laser posterior capsulotomy is the standard treatment for PCO-related visual impairment. Recurrence of PCO after initial treatment with YAG capsulotomy, though more common in children, is rare in adults. Its underlying pathophysiological mechanisms are similar to that of primary PCO, which includes proliferation, migration, and/or clustering of lens epithelial cells (LECs), with subsequent reclosure of the posterior aperture. Potential risk factors for PCO recurrence that have been speculated through a comprehensive search of the current literature include younger age, female sex, high myopia, diabetes, vitrectomized status, uveitis, low-diopter IOLs, and certain IOL types with higher water content. We present a case of recurrent PCO in a highly myopic 48-year-old male following cataract surgery and implantable collamer lens (ICL) explantation who received a hydrophobic acrylic lens with 4% water content. Surgical techniques that may reduce recurrent PCO occurrence and appropriate postoperative care are emphasized to assist surgeons in their approach to patients at high-risk for this complication.

后囊不透明(PCO)又称 "继发性白内障",是白内障手术后常见的并发症,会严重影响视力。受眼球内人工晶体(IOL)类型和患者风险因素的影响,文献中 PCO 的发生率差异很大。掺钕钇铝石榴石(YAG)激光后囊切开术是治疗 PCO 相关视力损害的标准方法。在使用 YAG 后囊切开术进行初次治疗后,PCO 复发的情况虽然在儿童中更为常见,但在成人中却很少见。其基本病理生理机制与原发性 PCO 相似,包括晶状体上皮细胞 (LEC) 的增殖、迁移和/或聚集,以及随后的后孔重新闭合。通过对现有文献的全面检索,我们推测 PCO 复发的潜在风险因素包括:年龄较小、女性、高度近视、糖尿病、玻璃体切割状态、葡萄膜炎、低屈光度人工晶体以及某些含水量较高的人工晶体类型。我们介绍了一例 48 岁高度近视男性在接受白内障手术和植入性人工晶体(ICL)取出术后复发 PCO 的病例,该患者接受了含水量为 4% 的疏水性丙烯酸人工晶体。该病例强调了可减少复发性 PCO 发生的手术技术和适当的术后护理,以帮助外科医生处理这种并发症的高风险患者。
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引用次数: 0
Oral Lesion Management in Juvenile SLE with Hepatosplenomegaly. 伴有肝脾肿大的青少年系统性红斑狼疮的口腔病变处理。
IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-23 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S476377
Adrianus Surya Wira Rajasa, Wahyu Hidayat

Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease with unknown etiology resulting in chronic multi-organ inflammation. Juvenile Systemic Lupus Erythematosus (JSLE) is a specific diagnosis of SLE in juvenile, characterized by oral ulceration.

Purpose: This case report attempts to provide information for oral medicine specialists in managing JSLE patients with hepatosplenomegaly.

Case presentation: A 17-year-old female patient was referred from the Pediatrics Department with mouth ulcers accompanied by dry lips and a tendency to bleed. The most concerning lesion was located on the left buccal mucosa, a single ulceration measuring 5x6mm. Multiple ulcerations spread over the upper and lower labial mucosa, with haemorrhagic crusts on the lips. Painful ulceration can lead to difficulties in mouth opening and impaired function in eating and drinking. Central erythema was seen on the palate. Pseudomembranous candidiasis was also seen on the patient's tongue. The hepatosplenomegaly was confirmed by CT scan, with enzyme values of SGPT (386 U/L) and SGOT (504 U/L).

Case management: Administration of 0.9% NaCl was instructed to the patient to maintain oral hygiene and help moisturize lips in order to remove haemorrhagic crusts. Administration of 0.025% hyaluronic acid mouthwash and topical steroid ointment mixture for ulcerated and inflammatory conditions. Drug adjustments were made based on laboratory tests and the patient's clinical condition was improving.

Conclusion: Managing oral symptoms helps reduce morbidity in JSLE patients. Topical corticosteroids are considered the first line in controlling oral inflammation. Dentists play a role in improving patients' oral hygiene with the aim of reducing the risk of other opportunistic infections.

背景:系统性红斑狼疮(SLE系统性红斑狼疮(SLE)是一种病因不明的自身免疫性疾病,会导致慢性多器官炎症。幼年系统性红斑狼疮(JSLE)是幼年系统性红斑狼疮的一种特殊诊断,以口腔溃疡为特征。目的:本病例报告试图为口腔内科专家管理伴有肝脾肿大的 JSLE 患者提供信息:一名 17 岁的女性患者因口腔溃疡伴有嘴唇干燥和出血倾向而从儿科转来。最令人担忧的病变位于左侧口腔粘膜,单个溃疡面积为 5x6mm。多个溃疡遍布上下唇粘膜,嘴唇上有出血结痂。溃疡疼痛可导致张口困难,进食和饮水功能受损。上颚可见中央红斑。患者的舌头上也出现了假膜性念珠菌病。CT 扫描证实了肝脾肿大,酶值为 SGPT(386 U/L)和 SGOT(504 U/L):指导患者服用 0.9% 的氯化钠,以保持口腔卫生并帮助滋润嘴唇,从而去除出血结痂。使用 0.025% 透明质酸漱口水和外用类固醇混合软膏治疗溃疡和炎症。根据实验室检测结果对药物进行了调整,患者的临床状况正在好转:结论:治疗口腔症状有助于降低 JSLE 患者的发病率。外用皮质类固醇激素被认为是控制口腔炎症的一线药物。牙医在改善患者口腔卫生方面发挥着作用,目的是降低其他机会性感染的风险。
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引用次数: 0
Mirror Image Dextrocardia with Severe Rheumatic Mitral Stenosis Undergone Successful Percutaneous Transvenous Commissurotomy: The First Case in East Africa. 镜像右心室伴严重风湿性二尖瓣狭窄成功经皮经静脉瓣口切开术:东非首例。
IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-19 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S439610
Kefelegn Dejene Tadesse, Yidnekachew Asrat Birhan

Percutaneous transvenous mitral commissurotomy is an established treatment for rheumatic mitral stenosis. Dextrocardic heart can be affected by rheumatic pathology just like the normal heart. However, it is technically demanding to percutaneous interventions especially the septal puncture which should be done in a mirror image of the normal. Here we are reporting a 45 year old woman with severe rheumatic mitral stenosis with dextrocardia with situs inversus totalis. She has undergone a successful percutaneous transvenous mitral commissurotomy.

经皮经静脉二尖瓣裂切开术是治疗风湿性二尖瓣狭窄的成熟疗法。二尖瓣狭窄的心脏也会像正常心脏一样受到风湿病变的影响。然而,它对经皮介入治疗的技术要求很高,尤其是室间隔穿刺术,应在正常心脏的镜像下进行。在此,我们报告了一名患有严重风湿性二尖瓣狭窄的 45 岁女性患者。她已成功接受了经皮经静脉二尖瓣裂切开术。
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引用次数: 0
Transfusion-Associated Circulatory Overload in a Healthy Patient Following a Road Traffic Accident: A Case Report. 道路交通事故后一名健康患者的输血相关循环负荷过重:病例报告。
IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-08 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S472055
Justine N Huang, Sara Mariam Amini, Christopher Fadumiye

Transfusion-associated circulatory overload (TACO) is a potentially fatal blood transfusion complication that often presents itself within 12 hours of transfusion cessation. We present a case of TACO in an orthopedic surgery patient to highlight the importance of anticipating and managing complications of blood loss and transfusion in an otherwise healthy patient.

输血相关循环负荷过重(TACO)是一种可能致命的输血并发症,通常在停止输血后 12 小时内出现。我们介绍了一例骨科手术患者的输血相关循环负荷过重(TACO)病例,以强调预测和处理健康患者失血和输血并发症的重要性。
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引用次数: 0
Optic Perineuritis Presenting with Transient Monocular Vision Loss (TMVL): Case Report. 视神经周围炎伴有短暂性单眼视力丧失(TMVL):病例报告。
IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-08 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S460611
Mohamed M Tawengi, Mohamad Fael, Rizeq F Hourani, Tamader Alyaarabi, Abdelaziz M Tawengi, Gamal Alfitori

Optic perineuritis is an inflammatory condition that presents with reduced visual acuity and painful eye movement. The presentation of optic perineuritis is similar of optic neuritis which results in delayed diagnosis and management. Up to this date, we found a single case of optic neuritis that presented with transient monocular vision loss (TMVL). No cases of optic perineuritis were associated with TMVL. Here, we report a case of a 30-year-old woman who presented with recurrent attacks of painless vision loss in her left eye, reaching up to 30 attacks per day. Ophthalmological examination was otherwise unremarkable. Lab investigations were normal. Magnetic resonance imaging was done, which showed left optic nerve sheath enhancement suggestive of left-sided focal optic perineuritis. Patient was managed with 1 mg IV methylprednisolone for 3 days. We report this case to shed light on the importance of accurate and early diagnosis of optic perineuritis presenting with TMVL. Prompt management of optic perineuritis is crucial in reducing morbidity and risk of relapse.

视神经周围炎是一种炎症,表现为视力下降和眼球运动疼痛。视神经周围炎的表现与视神经炎相似,这导致了诊断和治疗的延误。迄今为止,我们发现一例视神经炎患者表现为一过性单眼视力下降(TMVL)。没有一例视神经周围炎与 TMVL 相关。在此,我们报告了一例 30 岁女性的病例,她的左眼无痛性视力下降反复发作,每天发作次数多达 30 次。眼科检查无其他异常。实验室检查正常。磁共振成像显示左侧视神经鞘强化,提示左侧局灶性视神经周围炎。患者接受了为期 3 天的 1 毫克甲基强的松龙静脉注射治疗。我们报告该病例的目的是为了阐明准确和早期诊断伴有颞下颌关节肿大的视神经周围炎的重要性。及时处理视神经周围炎对于降低发病率和复发风险至关重要。
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引用次数: 0
Case Report of Severe Chlamydia psittaci Pneumonia Treated with Omadacycline. 用奥马大环素治疗严重鹦鹉热衣原体肺炎的病例报告
IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-04 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S473469
Yan Chen, Jiahuan Tong, Jianfeng Wang

The clinical severity of Chlamydia psittaci infection ranges from asymptomatic to severe pneumonia. Diagnosis poses challenges due to its similarity to other respiratory infections. Treatment includes tetracyclines, macrolides, and fluoroquinolones, with limited evidence on the efficacy of omadacycline. We report a case of an 86-year-old male with severe psittacosis treated with omadacycline, resulting in significant improvement. This highlights the necessity for further research on omadacycline's role in psittacosis treatment.

鹦鹉热衣原体感染的临床严重程度从无症状到重症肺炎不等。由于它与其他呼吸道感染相似,因此给诊断带来了挑战。治疗方法包括四环素类、大环内酯类和氟喹诺酮类药物,但奥马他环素的疗效证据有限。我们报告了一例患有严重鹦鹉热的 86 岁男性病例,患者在接受奥美拉唑治疗后病情明显好转。这凸显了进一步研究奥马大环素在鹦鹉热治疗中的作用的必要性。
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引用次数: 0
Primary Omentum Malignant Hemangiopericytoma Present with Acute Abdomen. 原发性网膜恶性血管瘤伴有急性腹部。
IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-03 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S469084
Burkan Nasr, Sameh Khalil Gazem, Rashad Saleh Al-Gahafy, Mohammed A Al-Hawbani

The greater omentum primary malignant tumors are rare, with less than 50 cases reported. Malignant hemangiopericytomas constitute only four of these cases. The common clinical manifestations of a malignant omental tumor are abdominal mass and pain. We report on a woman 38 years old who came to the hospital's emergency department with a finding consisting of intestinal obstruction (abdominal pain, constipation, abdominal distention, and vomiting), and during a clinical examination a mass was discovered in the lower half of her abdomen. She had been experiencing these symptoms for three days before her arrival. During a clinical examination, a large size, hard mobile mass was discovered in the lower half of her abdomen. The patient underwent an abdominal CT scan which indicated the presence of a sizable, soft tissue mass located within the abdominal and pelvic region, exerting pressure on the small bowel loops, with mild free ascites. Due to the patient's acute abdomen, an exploration laparotomy was performed, revealing a large mass in the omentum measuring 20×20×10 cm and weighing 3 kg. The mass, along with the omentum, was completely removed, and histopathology confirmed a malignant hemangiopericytoma.

大网膜原发性恶性肿瘤非常罕见,报道的病例不到 50 例。恶性血管肉瘤仅占其中的四例。恶性大网膜肿瘤常见的临床表现为腹部肿块和疼痛。我们报告了一名 38 岁女性的病例,她因肠梗阻(腹痛、便秘、腹胀和呕吐)来医院急诊科就诊,在临床检查中发现她的下腹部有肿块。她在就诊前三天就出现了这些症状。在临床检查中,她的下腹部发现了一个大而坚硬的移动肿块。患者接受了腹部 CT 扫描,结果显示腹部和盆腔内有一个相当大的软组织肿块,压迫小肠襻,并伴有轻度游离腹水。由于患者急腹症,医生对其进行了探查性开腹手术,发现网膜上有一个大肿块,大小为 20×20×10 厘米,重达 3 公斤。肿块和网膜被完全切除,组织病理学证实为恶性血管瘤。
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引用次数: 0
Neurosyphilis Presenting as Psychiatric Symptoms at Younger Age: A Case Report. 年轻时出现精神症状的神经梅毒:病例报告。
IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-02 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S477459
Hong-Yan Li, Hao-Yu Wang, Yi-Fei Duan, Yu Gou, Xiao-Qin Liu, Zheng-Xiang Gao

Neurosyphilis is a central nervous system infection caused by Treponema pallidum that imitates various neurological and mental disorders. Therefore, patients with this disease are prone to misdiagnoses. Here, we report a case of neurosyphilis with a psychotic disorder as the main manifestation. A young girl exhibited mental and behavioural abnormalities after a heartbreak, which manifested as alternating low mood, emotional irritability, and a lack of interest in social relations, followed by memory loss. The cerebrospinal fluid protein - Treponema pallidum particle agglutination test was positive, the toluidine red unheated serum test titre was 1:4, the white blood cell count was 5 × 10^6/L, the cerebrospinal fluid protein level was 0.97 g/L, and the brain CT was abnormal. After admission, the possibility of neurosyphilis was considered and the patient received intravenous penicillin G treatment. The patient's clinical symptom ms improved. This case emphasises that doctors should maintain clinical suspicion of Treponema pallidum infection in adolescent patients with mental abnormalities.

神经梅毒是由苍白螺旋体引起的中枢神经系统感染,会模仿各种神经和精神疾病。因此,该病患者很容易被误诊。在此,我们报告了一例以精神障碍为主要表现的神经梅毒患者。一名年轻女孩在一次失恋后出现精神和行为异常,表现为交替性情绪低落、易激惹、对社交关系缺乏兴趣,随后出现记忆力减退。脑脊液蛋白-苍白螺旋体颗粒凝集试验阳性,甲苯胺红不加热血清试验滴度为 1:4,白细胞计数为 5×10^6/L,脑脊液蛋白水平为 0.97g/L,脑 CT 异常。入院后,考虑到神经梅毒的可能性,患者接受了青霉素 G 静脉注射治疗。患者的临床症状毫秒级改善。本病例强调,对于精神异常的青少年患者,医生在临床上应继续怀疑他们是否感染了苍白螺旋体。
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引用次数: 0
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International Medical Case Reports Journal
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