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Ashtanga Yoga Ethics-Based Yoga Versus General Yoga on Anthropometric Indices, Trigunas, and Quality of Life in Abdominal Obesity: A Randomized Control Trial. 基于阿斯汤加瑜伽伦理的瑜伽与普通瑜伽对腹部肥胖患者的人体测量指数、三角区和生活质量的影响:一项随机对照试验。
IF 1.6 Pub Date : 2022-05-01 Epub Date: 2022-09-05 DOI: 10.4103/ijoy.ijoy_63_22
Aruna Mewada, Jyoti Keswani, Hemanshu Sharma, Gulab Rai Tewani, Pradeep M K Nair

Introduction: The philosophical tenets of yoga such as Ashtanga yoga (AY) and Trigunas are seldom considered while designing yoga programs for chronic diseases. This randomized control trial explored the impact of AY principle-based yoga on the anthropometric indices, personality traits, and quality of life (QoL) in abdominal obesity (AO).

Materials and methods: Sixty-two participants with AO were randomized (n = 31 in each arm) into an AY arm or general yoga (GY) arm. For 12 weeks, both the AY and the GY received the same yoga protocol; however, the AY received an additional AY-based orientation session fortnightly. Changes in waist circumference, hip circumference (HC), height, weight, body mass index (BMI), waist-hip ratio, Vedic Personality Inventory for gunas, and World Health Organization QoL-BREF were measured at baseline and at the end of 12 weeks.

Results: By the end of 12 weeks, the AY arm significantly differed from the GY arm in HC (P = 0.05) and BMI scores (P = 0.03). The AY arm has shown a significant increase in the sattva guna (P < 0.001) and reduction in the rajas (P < 0.001) and tamas gunas (P = 0.03). There was a significant improvement in the physical and social QoL domain, whereas the other variables examined remained insignificant. The increase in sattva guna was negatively correlated with waist circumference (P = -0.489) and BMI (r = -0.553).

Conclusion: Exposing participants to progressive AY philosophy can change the personality traits which are further associated with melioration in the determiners of AO. Future yoga programs for chronic disorders may consider including AY philosophy for substantive outcomes.

在设计针对慢性疾病的瑜伽课程时,很少考虑到瑜伽的哲学原则,如阿斯汤加瑜伽(AY)和Trigunas。这项随机对照试验探讨了基于AY原则的瑜伽对腹部肥胖(AO)患者的人体测量指标、人格特征和生活质量(QoL)的影响。材料和方法:将62名AO患者随机分为AY组和普通瑜伽组(GY)。在12周的时间里,AY组和GY组都采用了相同的瑜伽方案;然而,助理助理每两周接受一次额外的以助理助理为基础的介绍会。在基线和12周结束时测量腰围、臀围(HC)、身高、体重、身体质量指数(BMI)、腰臀比、古纳斯的吠陀人格量表和世界卫生组织QoL-BREF的变化。结果:在12周结束时,AY组与GY组在HC (P = 0.05)和BMI评分(P = 0.03)上有显著差异。AY组的sattva guna显著增加(P < 0.001), rajas (P < 0.001)和tamas gunas (P = 0.03)显著减少。在身体和社会生活质量领域有显著改善,而其他变量检查仍然不显著。sattva guna的增加与腰围(P = -0.489)和BMI (r = -0.553)呈负相关。结论:让被试接受渐进式的AY哲学可以改变他们的人格特质,进而改善AO的决定因素。未来针对慢性疾病的瑜伽项目可能会考虑纳入AY哲学以获得实质性的结果。
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引用次数: 1
Integrative Approach Improves Fall Risk and Postural Stability in Spinocerebellar Ataxia-2 - A Case Report. 综合治疗方法可提高脊柱小脑共济失调患者跌倒风险和姿势稳定性-2 - 1例报告。
IF 1.6 Pub Date : 2022-05-01 Epub Date: 2022-09-05 DOI: 10.4103/ijoy.ijoy_49_22
Kavyashree Kulamarva, Umesh Chikkanna, Kishore Kumar Ramakrishna, Hemant Bhargav, Selva Ganapathy Velayutham, Shivarama Varambally

Spinocerebellar ataxias (SCAs) comprise a large heterogeneous group of autosomal dominant cerebellar ataxias. Despite availability of various conventional treatments, reducing disability and improving the quality of life is a challenge in this condition. In the present case report, based on the clinical symptoms and site of pathology, an Ayurveda-based diagnosis of kaphavruta vayana and kaphavruta udana was considered. Therapeutic measures such as rookshana (drying therapy), vatahara (measures to pacifying vata), balya (strengthening), and brimhana (nourishing) regimens were adopted along with oral medications and specific yoga practices. The objective of the treatment was to improve stability, posture, and balance. After 10 weeks of integrative treatment, a demonstrable improvement was observed in scale for assessment and rating of ataxia Scale for the Assessment and Rating of Ataxia (SARA), fall risk, and limit of stability (using computerized dynamic posturography). Hence, an integrated Ayurveda and Yoga-based lifestyle regimen may serve as a useful adjuvant in improving fall risk and limit of stability in patients with SCAs.

脊髓小脑共济失调(SCAs)包括一个大的异构群常染色体显性小脑共济失调。尽管有各种常规治疗方法,但在这种情况下,减少残疾和提高生活质量仍是一项挑战。在本病例报告中,根据临床症状和病理部位,考虑了基于阿育吠陀的kaphavruta vayana和kaphavruta udana诊断。治疗措施,如rookshana(干燥疗法)、vatahara(安抚vata的措施)、balya(加强)和brimhana(滋养)方案,以及口服药物和特定的瑜伽练习都被采用。治疗的目的是改善稳定性、姿势和平衡。综合治疗10周后,观察到共济失调评估评分量表(SARA)、跌倒风险和稳定性极限(使用计算机动态姿势照相)的评估和评分明显改善。因此,以阿育吠陀和瑜伽为基础的综合生活方式方案可以作为一种有用的辅助手段,改善sca患者的跌倒风险和稳定性限制。
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引用次数: 0
Scientific Evidence of Health Benefits by Practicing Mantra Meditation: Narrative Review. 通过练习魔咒冥想对健康有益的科学证据:叙述回顾。
IF 1.6 Pub Date : 2022-05-01 Epub Date: 2022-09-05 DOI: 10.4103/ijoy.ijoy_53_22
Ampere A Tseng

Mantra meditation (MM) is one of the simplest and most effective meditative practices suitable for both novice and skillful meditators. It has attracted a significant number of practitioners for various health benefits or for spiritual inspiration. The scope of this review article focuses on the examination of the health benefits of practicing MM without considering the motivation by spiritual rewarding or cultivation. Through the examination, we attempt to confirm and to add scientific evidence on the benefits of mental and physical health to the practitioners. We review a large number of the recent studies of MM for understanding the mechanism in yielding medical benefits and for analyzing the quantitative evidence of the trial outcomes. The review covers four important areas: stress, anxiety, hypertension, and immunity, with the hope to evoke more studies to refine the current evidence and to encourage more studies in other promising areas. Furthermore, the review gives more attention or discussion on more recent, original, and stronger studies. The discussion can include the strong or weak points of the reviewed studies. The review discovers evidence that MM can provide various degrees of beneficial effects on the four areas considered. Studies with larger participants, superior quality, and a few others are recommended to draw firm conclusions. Several promising research areas and directions are also suggested.

咒语冥想(MM)是最简单和最有效的冥想练习之一,适合新手和熟练的冥想者。它吸引了大量的从业者,以获得各种健康益处或精神灵感。这篇综述文章的范围主要集中在检查实践MM的健康益处,而不考虑精神奖励或培养的动机。通过检查,我们试图确认并增加科学证据,对从业者的精神和身体健康的好处。我们回顾了大量最近关于MM的研究,以了解其产生医疗效益的机制,并分析试验结果的定量证据。这篇综述涵盖了四个重要领域:压力、焦虑、高血压和免疫,希望能唤起更多的研究来完善现有的证据,并鼓励在其他有前途的领域进行更多的研究。此外,这篇综述对最近的、原创的、更有力的研究给予了更多的关注或讨论。讨论可以包括所审查研究的优点或缺点。审查发现证据表明,MM可以提供不同程度的有利影响的四个领域考虑。建议采用更大的参与者、更高的质量和其他一些研究来得出确切的结论。并提出了几个有前景的研究领域和方向。
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引用次数: 5
Consciousness, Awareness, and Presence: A Neurobiological Perspective. 意识、觉知和存在:一个神经生物学的视角。
IF 1.6 Pub Date : 2022-05-01 Epub Date: 2022-09-05 DOI: 10.4103/ijoy.ijoy_77_22
Vinod D Deshmukh

It is proposed that consciousness is different from awareness. Consciousness can be thought of as a dualistic, embodied, and embedded cognitive process, whereas awareness is a nondual and nonlocal process. Nonlocal awareness is the ever-present, ever-fresh, and an affective self-awareness that can be aware of itself as well as of the ongoing subject-object duality, and cognitive conscious contents. This nonlocal awareness is our default mode state. Although very few of us are aware of it due to our habitual mental preoccupation and mind-wandering. We need to relax, learn to meditate, let go of all preoccupations, and return to our default mode state of being, which is peaceful, silent, fulfilling, energetic, and ever-fresh. Then, one feels effortlessly alive and free and at home in the world. This is the essence of meditation for living a happy, peaceful, and meaningful life. The rest of the article provides details of meditative presence, yoga meditation, and mindfulness meditation with their current practice and applications. The main focus of the article is on the neurobiology of meditation, which is discussed in detail. It covers the experientially perceived mind-space including personal, peripersonal, and extrapersonal space, the concepts of mind in the Western and Eastern literature, and the neurobiological foundation in the brain stem, reticular-limbic system, forebrain including the five thalamo-cortical-basal ganglia circuits, multiple sensory modalities, integrated perception, speech production, language communication, voluntary movements, and intentional actions. The wholeness of conscious mind is expressed as bio-psycho-social-abstract/spiritual.

有人提出,意识不同于意识。意识可以被认为是一个二元的、具体化的、嵌入的认知过程,而意识是一个非二元的、非局部的过程。非局部意识是一种常存的、常存的、情感的自我意识,既能意识到自身,又能意识到正在进行的主客体二元性和认知意识内容。这种非本地感知是我们的默认模式状态。虽然很少有人意识到这一点,因为我们习惯性的精神专注和走神。我们需要放松,学习冥想,放下所有的烦恼,回到我们的默认状态,那就是和平、沉默、充实、充满活力和永远新鲜。然后,一个人会毫不费力地感到活着、自由和自在。这是冥想的精髓,它能让你过上快乐、平静、有意义的生活。本文的其余部分将详细介绍冥想、瑜伽冥想和正念冥想,以及它们当前的实践和应用。这篇文章的主要焦点是冥想的神经生物学,这是详细讨论。它涵盖了经验感知的心灵空间,包括个人、周围个人和超个人空间,西方和东方文献中的心灵概念,以及脑干的神经生物学基础,网状边缘系统,前脑,包括五个丘脑-皮质-基底神经节回路,多种感觉模式,综合感知,语言产生,语言交流,自愿运动和有意行为。意识心灵的整体被表达为生物心理社会抽象/精神。
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引用次数: 1
Yoga and Integrative Healthcare: Lessons from the National Institute of Mental Health and Neurosciences (NIMHANS) in India. 瑜伽与综合保健:印度国家心理健康和神经科学研究所(NIMHANS)的经验。
IF 1.1 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2022-05-01 Epub Date: 2022-09-05 DOI: 10.4103/ijoy.ijoy_56_22
Hemant Bhargav, Bharath Holla, Kishore Kumar Ramakrishna, Venkataram Shivakumar, K Gokulakrishnan, Shivarama Varambally, B N Gangadhar

Background: There is growing evidence and increasing interest for systemic integration of medicine (synergistic and evidence-based combination of different systems along with conventional biomedicine). The National Institute of Mental Health and Neurosciences (NIMHANS), an Institute of National Importance and a tertiary mental and neurological healthcare hospital situated in Bengaluru, India, has established one such integrative model. The present manuscript traces the history and describes the important steps followed in this integrative approach.

Methodology: The NIMHANS model followed a stage-wise two-step approach: (1) First stage - Starting with Integration of Yoga: The process began more than a decade ago, with integrating yoga into a clinical department (rather than an exclusive research-based approach) of the institute which had relatively high clinical service load (For example, Department of Psychiatry in NIMHANS). Yoga was gradually formalized into academic and clinical activities (outpatient and inpatient services) by appointing a Yoga faculty with a medical background with an MD/PhD in Yoga. The research was primarily directed by the clinical observations of patients receiving yoga therapy. (2) Second stage: Adding an appropriate and compatible discipline from Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy (AYUSH) system (Ayurveda in this case): The center for yoga gradually evolved into the Department of Integrative Medicine with the appointment of faculty from the Ayurveda stream. In this model, specialists from each discipline provide clinical inputs after simultaneous consultation with the patient through systemic integration in clinical, academic, and research domains rather than mere co-location of AYUSH services with mainstream medicine.

Conclusion: The NIMHANS model of integration suggests the application of yoga into mainstream clinical service as the first step toward integration. Yoga should be added as a formalized clinical discipline with systemic integration. Gradually, other feasible systems of traditional medicine from AYUSH can be integrated at a later stage in a step-by-step manner based on clinical practice and evidence.

背景:有越来越多的证据表明,人们对系统整合医学(不同系统与传统生物医学的协同和循证结合)越来越感兴趣。位于印度班加罗尔的国家精神卫生和神经科学研究所(NIMHANS)是一家国家级研究所,也是一家三级精神和神经医疗保健医院。本手稿追溯了这一综合方法的历史,并介绍了其重要步骤:NIMHANS 模式遵循分阶段的两步方法:(1)第一阶段--从整合瑜伽开始:这一过程始于十多年前,当时是将瑜伽整合到临床服务负荷相对较高的研究所的临床部门(而不是以研究为基础的独家方法)(例如 NIMHANS 的精神病学系)。通过任命一名具有医学背景的瑜伽教员和一名瑜伽医学博士/博士,瑜伽逐渐被正式纳入学术和临床活动(门诊和住院服务)。研究的主要方向是对接受瑜伽治疗的病人进行临床观察。(2) 第二阶段:从阿育吠陀、瑜伽和自然疗法、尤那尼、悉达和顺势疗法(AYUSH)系统中添加一门适当且兼容的学科(这里指的是阿育吠陀):随着阿育吠陀学系教师的任命,瑜伽中心逐渐发展成为综合医学系。在这一模式中,各学科的专家通过在临床、学术和研究领域的系统整合,在与病人同步会诊后提供临床投入,而不仅仅是将阿育吠陀医学服务与主流医学放在一起:结论:NIMHANS 整合模式建议将瑜伽应用到主流临床服务中,作为实现整合的第一步。瑜伽应作为一门正式的临床学科与系统整合。在以后的阶段,可以根据临床实践和证据,逐步整合来自 AYUSH 的其他可行的传统医学体系。
{"title":"Yoga and Integrative Healthcare: Lessons from the National Institute of Mental Health and Neurosciences (NIMHANS) in India.","authors":"Hemant Bhargav, Bharath Holla, Kishore Kumar Ramakrishna, Venkataram Shivakumar, K Gokulakrishnan, Shivarama Varambally, B N Gangadhar","doi":"10.4103/ijoy.ijoy_56_22","DOIUrl":"10.4103/ijoy.ijoy_56_22","url":null,"abstract":"<p><strong>Background: </strong>There is growing evidence and increasing interest for systemic integration of medicine (synergistic and evidence-based combination of different systems along with conventional biomedicine). The National Institute of Mental Health and Neurosciences (NIMHANS), an Institute of National Importance and a tertiary mental and neurological healthcare hospital situated in Bengaluru, India, has established one such integrative model. The present manuscript traces the history and describes the important steps followed in this integrative approach.</p><p><strong>Methodology: </strong>The NIMHANS model followed a stage-wise two-step approach: (1) First stage - <i>Starting with Integration of Yoga</i>: The process began more than a decade ago, with integrating yoga into a clinical department (rather than an exclusive research-based approach) of the institute which had relatively high clinical service load (For example, Department of Psychiatry in NIMHANS). Yoga was gradually formalized into academic and clinical activities (outpatient and inpatient services) by appointing a Yoga faculty with a medical background with an MD/PhD in Yoga. The research was primarily directed by the clinical observations of patients receiving yoga therapy. (2) Second stage: <i>Adding an appropriate and compatible discipline from</i> Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy <i>(AYUSH) system (Ayurveda in this case)</i>: The center for yoga gradually evolved into the Department of Integrative Medicine with the appointment of faculty from the Ayurveda stream. In this model, specialists from each discipline provide clinical inputs after simultaneous consultation with the patient through systemic integration in clinical, academic, and research domains rather than mere co-location of AYUSH services with mainstream medicine.</p><p><strong>Conclusion: </strong>The NIMHANS model of integration suggests the application of yoga into mainstream clinical service as the first step toward integration. Yoga should be added as a formalized clinical discipline with systemic integration. Gradually, other feasible systems of traditional medicine from AYUSH can be integrated at a later stage in a step-by-step manner based on clinical practice and evidence.</p>","PeriodicalId":14436,"journal":{"name":"International Journal of Yoga","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c9/af/IJY-15-150.PMC9623895.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40443246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Yoga on Stress, Anxiety, Depression, and Spinal Mobility in Computer Users with Chronic Low Back Pain. 瑜伽对慢性腰痛电脑使用者的压力、焦虑、抑郁和脊柱活动的影响。
IF 1.6 Pub Date : 2022-05-01 Epub Date: 2022-09-05 DOI: 10.4103/ijoy.ijoy_9_22
Chametcha Singphow, SatyaPrakash Purohit, Padmini Tekur, Suman Bista, Surya Narayan Panigrahy, Nagarathna Raghuram, Hongasandra Ramarao Nagendra

Background: Office workers who need to use a computer while maintaining a static position for prolonged periods have more chance of having low back pain (LBP).

Objective: The objective of the study is to investigate the effect of yoga on stress, anxiety, depression, and spinal mobility in computer users with chronic LBP (CLBP).

Materials and methods: In this randomized control trial, eighty computer users (42.6 ± 8.45 years of age; suffering from CLBP since 5.20 ± 3.01 years; 51 males and 29 females) who use a computer for their professional work, recruited from Bengaluru, India, were randomized into two groups: yoga group (n = 40) and physical exercise group (n = 40). The yoga group practiced an integrated module comprising yoga postures and mindfulness meditation, and the physical exercise group practiced physical exercise designed for LBP (1 h/day, 3 days/week for 16 weeks). Assessments of dial-type goniometer and Depression Anxiety Stress Scale-42 were performed at baseline, after 8 weeks, and after 16 weeks.

Results: Stress, anxiety, and depression scores were significantly lower in the yoga group as compared to the physical exercise group at 16 weeks (P < 0.001), whereas spinal flexion (P < 0.001), spinal extension (P < 0.001), right lateral flexion (P = 0.001), and left lateral flexion (P = 0.007) scores were significantly higher in the yoga group as compared to the physical exercise group at 16 weeks.

Conclusion: Yoga is more effective in reducing stress, anxiety, and depression and improving spinal mobility in computer users with CLBP than physical exercise designed for LBP.

背景:需要长时间保持静止姿势使用电脑的办公室职员更有可能患上腰痛。目的:本研究的目的是探讨瑜伽对慢性腰痛(CLBP)电脑用户的压力、焦虑、抑郁和脊柱活动的影响。材料与方法:在本随机对照试验中,80例计算机使用者(42.6±8.45岁;患CLBP 5.20±3.01年;从印度班加罗尔招募了51名在工作中使用电脑的男性和29名女性,随机分为两组:瑜伽组(n = 40)和体育锻炼组(n = 40)。瑜伽组练习由瑜伽姿势和正念冥想组成的综合模块,体育锻炼组练习为LBP设计的体育锻炼(每天1小时,每周3天,持续16周)。在基线、8周后和16周后分别对刻度盘式测角仪和抑郁焦虑压力量表-42进行评估。结果:与体育锻炼组相比,瑜伽组在16周时的压力、焦虑和抑郁评分显著降低(P < 0.001),而在16周时,瑜伽组的脊柱屈曲(P < 0.001)、脊柱伸展(P < 0.001)、右侧侧屈(P = 0.001)和左侧侧屈(P = 0.007)评分显著高于体育锻炼组。结论:与专为LBP设计的体育锻炼相比,瑜伽在减轻CLBP计算机用户的压力、焦虑和抑郁以及改善脊柱活动能力方面更有效。
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引用次数: 2
Estimation of Yoga Postures Using Machine Learning Techniques. 用机器学习技术估计瑜伽姿势。
IF 1.6 Pub Date : 2022-05-01 Epub Date: 2022-09-05 DOI: 10.4103/ijoy.ijoy_97_22
D Mohan Kishore, S Bindu, Nandi Krishnamurthy Manjunath

Yoga is a traditional Indian way of keeping the mind and body fit, through physical postures (asanas), voluntarily regulated breathing (pranayama), meditation, and relaxation techniques. The recent pandemic has seen a huge surge in numbers of yoga practitioners, many practicing without proper guidance. This study was proposed to ease the work of such practitioners by implementing deep learning-based methods, which can estimate the correct pose performed by a practitioner. The study implemented this approach using four different deep learning architectures: EpipolarPose, OpenPose, PoseNet, and MediaPipe. These architectures were separately trained using the images obtained from S-VYASA Deemed to be University. This database had images for five commonly practiced yoga postures: tree pose, triangle pose, half-moon pose, mountain pose, and warrior pose. The use of this authentic database for training paved the way for the deployment of this model in real-time applications. The study also compared the estimation accuracy of all architectures and concluded that the MediaPipe architecture provides the best estimation accuracy.

瑜伽是印度传统的保持身心健康的方式,通过身体姿势(体式)、自主调节呼吸(调息)、冥想和放松技巧。最近的大流行导致瑜伽练习者人数激增,许多人在没有适当指导的情况下练习。本研究旨在通过实施基于深度学习的方法来简化这些从业者的工作,该方法可以估计从业者执行的正确姿势。该研究使用四种不同的深度学习架构(EpipolarPose、OpenPose、PoseNet和MediaPipe)实现了这种方法。这些架构分别使用从S-VYASA被认为是大学获得的图像进行训练。这个数据库有五种常用的瑜伽姿势的图像:树式、三角式、半月式、山式和战士式。使用这个真实的数据库进行训练,为在实时应用程序中部署该模型铺平了道路。该研究还比较了所有体系结构的估计精度,并得出结论,MediaPipe体系结构提供了最好的估计精度。
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引用次数: 7
Effect of Tratak (Yogic Ocular Exercises) on Intraocular Pressure in Glaucoma: An RCT Tratak(Yogic Ocular Exercise)对青光眼眼压的影响:随机对照试验
IF 1.6 Pub Date : 2022-01-01 DOI: 10.4103/ijoy.ijoy_160_21
Sankalp, T. Dada, R. Yadav, H. Sharma, R. Netam, K. Kochhar
Introduction: In healthy subjects, the intraocular pressure (IOP) is maintained by a dynamic equilibrium between continuous production of aqueous humor by ciliary bodies and continuous outflow through the two drainage pathways: trabecular meshwork and uveoscleral outflow. Here, we hypothesized that yogic ocular exercises, including extraocular muscles exercise, and modified Tratak Kriya (mTK), might reduce the IOP as well as stress and improve quality of life (QoL) in patients with glaucoma. Methodology: A parallel two-arm randomized controlled trial (RCT) was conducted in glaucoma patients (Control group and Intervention group). Control group patients were on standard medical treatment and intervention group patients practiced a Yoga-based lifestyle intervention (YBLI) for 4 weeks as add-on therapy with their standard medical treatment. All Participants were assessed at baseline day 1, day 14 (D14), and day 28 (D28). A minimum of 30 patients were recruited in each group. Results: We did not observe any statistically significant different mean IOP of right (IOP-r) or, left eyes at any time point as well as cortisol level and QoL between the two groups. However, with in intervention group, there was a reduction in IOP-r at D14 (15.54 ± 2.81 mmHg) and D28 (15.24 ± 3.1 mmHg), P = 0.006 and 0.001, respectively, compared to their baseline IOP (16.26 ± 2.98). Conclusion: Based on the present RCT, yoga-based ocular exercises practiced here cannot be recommended for management of raised IOP in glaucoma patients. Further larger studies are warranted with yoga-based interventions in patients with glaucoma. Clinical Trial Registration Number CTRI/2016/03/006703
引言:在健康受试者中,眼压(IOP)是通过睫状体持续产生房水和通过两种引流途径(小梁网和葡萄膜巩膜流出)持续流出之间的动态平衡来维持的。在这里,我们假设瑜伽眼部运动,包括眼外肌肉运动和改良Tratak Kriya(mTK),可能会降低青光眼患者的眼压和压力,提高生活质量。方法:对青光眼患者(对照组和干预组)进行平行的双臂随机对照试验(RCT)。对照组患者接受标准药物治疗,干预组患者进行为期4周的瑜伽生活方式干预(YBLI),作为标准药物治疗的附加治疗。所有参与者在基线第1天、第14天(D14)和第28天(D28)进行评估。每组至少招募30名患者。结果:我们没有观察到两组在任何时间点右眼或左眼的平均眼压(IOP-r)以及皮质醇水平和生活质量有任何统计学意义的差异。然而,与基线眼压(16.26±2.98)相比,干预组在D14(15.54±2.81 mmHg)和D28(15.24±3.1 mmHg)时的眼压-r分别降低了,P=0.006和0.001。有必要对青光眼患者进行基于瑜伽的干预进行更大规模的研究。临床试验注册号CTRI/2016/03/006703
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引用次数: 5
Multi-omics integration and interactomics reveals molecular networks and regulators of the beneficial effect of yoga and exercise 多组学整合和相互作用揭示了瑜伽和锻炼有益效果的分子网络和调节因子
IF 1.6 Pub Date : 2022-01-01 DOI: 10.4103/ijoy.ijoy_146_21
Manoj Khokhar, S. Tomo, A. Gadwal, P. Purohit
Background: Yoga is a multifaceted spiritual tool that helps in maintaining health, peace of mind, and positive thoughts. In the context of asana, yoga is similar to physical exercise. This study aims to construct a molecular network to find hub genes that play important roles in physical exercise and yoga. Methodology: We combined differentially expressed genes (DEGs) in yoga and exercise using computational bioinformatics from publicly available gene expression omnibus (GEO) datasets and identified the codifferentially expressed mRNAs with GEO2R. The co-DEGs were divided into four different groups and each group was subjected to protein–protein interaction (PPI) network, pathways analysis, and gene ontology. Results: Our study identified immunological modulation as a dominant target of differential expression in yoga and exercise. Yoga predominantly modulated genes affecting the Th1 and NK cells, whereas Cytokines, Macrophage activation, and oxidative stress were affected by exercise. We also observed that while yoga regulated genes for two main physiological functions of the body, namely Circadian Rhythm (BHLHE40) and immunity (LBP, T-box transcription factor 21, CEACAM1), exercise-regulated genes involved in apoptosis (BAG3, protein kinase C alpha), angiogenesis, and cellular adhesion (EPH receptor A1). Conclusion: The dissimilarity in the genetic expression patterns in Yoga and exercise highlights the discrete effect of each in biological systems. The integration and convergences of multi-omics signals can provide deeper and comprehensive insights into the various biological mechanisms through which yoga and exercise exert their beneficial effects and opens up potential newer research areas.
背景:瑜伽是一种多方面的精神工具,有助于保持健康、心灵平静和积极的想法。在体式的背景下,瑜伽类似于体育锻炼。这项研究旨在构建一个分子网络,寻找在体育锻炼和瑜伽中发挥重要作用的枢纽基因。方法:我们使用来自公开基因表达综合(GEO)数据集的计算生物信息学,将瑜伽和锻炼中的差异表达基因(DEGs)结合起来,并用GEO2R鉴定了共差异表达的mRNA。共DEG被分为四组,每组接受蛋白质-蛋白质相互作用(PPI)网络、通路分析和基因本体论。结果:我们的研究确定免疫调节是瑜伽和运动中差异表达的主要靶点。瑜伽主要调节影响Th1和NK细胞的基因,而细胞因子、巨噬细胞激活和氧化应激受运动影响。我们还观察到,虽然瑜伽调节身体两种主要生理功能的基因,即昼夜节律(BHLHE40)和免疫(LBP,T-box转录因子21,CEACAM1),但运动调节参与细胞凋亡(BAG3,蛋白激酶Cα)、血管生成和细胞粘附(EPH受体A1)的基因。结论:瑜伽和运动中基因表达模式的差异凸显了两者在生物系统中的离散效应。多组学信号的整合和汇聚可以对瑜伽和锻炼发挥有益作用的各种生物学机制提供更深入和全面的见解,并开辟潜在的新研究领域。
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引用次数: 1
East Meets West in Therapeutic Approaches to the Management of Chronic Pain 东西方在慢性疼痛管理的治疗方法中相遇
IF 1.6 Pub Date : 2022-01-01 DOI: 10.4103/ijoy.ijoy_104_21
E. Hapidou, Ting Huang
Yoga as a holistic principle, not only practice of asanas or poses, integrates all aspects of the self, with biological, mental, intellectual, and spiritual elements. Yoga encompasses the biopsychosocial medical perspective, which regards pain as a dynamic interaction between physiological, psychological, and social factors. The purpose of this perspective article is to compare and contrast psychological practices such as mindfulness meditation, relaxation response (RR), and cognitive behavioral therapy (CBT) with Yoga in their management of chronic pain. The use of these practices is explored through history, literature, and research studies. Results from scientific studies on Yoga show changes in health-related pain outcomes for patients with chronic pain. The key aspects of Yoga, notably relaxation, positive thinking, and mindfulness, are discussed in relation to mindfulness meditation, RR, and CBT.
瑜伽作为一种整体原则,不仅仅是体式或姿势的练习,它整合了自我的各个方面,包括生物、心理、智力和精神元素。瑜伽包含了生物心理社会医学的观点,它认为疼痛是生理、心理和社会因素之间的动态相互作用。这篇透视文章的目的是比较和对比心理学练习,如正念冥想、放松反应(RR)和认知行为疗法(CBT)与瑜伽在治疗慢性疼痛方面的效果。这些实践的使用是通过历史、文学和研究来探索的。关于瑜伽的科学研究结果显示,慢性疼痛患者的健康相关疼痛结果发生了变化。瑜伽的关键方面,特别是放松,积极思考和正念,讨论了正念冥想,RR和CBT的关系。
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引用次数: 1
期刊
International Journal of Yoga
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