International Wound Journal最新文献

EXPRESSION OF CONCERN: A. K. Mousa, A. A. Elshenawy, S. M. Maklad, S. M. M. Bebars, H. A. Burezq, S. E. Sayed, “Post-Burn Scar Malignancy: 5-Year Management Review and Experience,” International Wound Journal 19, no. 4 (2022): 895–909, https://doi.org/10.1111/iwj.13690.

This Expression of Concern is for the above article, published online on 14 August 2023 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editor-in-Chief, Professor Keith Harding; and John Wiley & Sons Ltd. An investigation by the publisher found that images in Figures 8B and 8C had been duplicated and rotated, albeit with different staining. In addition, the investigation found that information regarding the study's ethical approval and informed consent procedure were unclear. In addition, the study reported in the article is not registered in a clinical trial registry, as required by the journal's guidelines.

The authors responded to an inquiry by the publisher stating that the article received approval from the Aswan University ethical committee and that the study was not registered in a clinical trial registry because no trial management protocol was applied to the study. The authors did not provide original ethical approval documents as requested and did not provide an explanation for the duplicated images nor all original data for the study. The Expression of Concern has been agreed to because the concerns regarding a duplicated image and lack of clarity regarding the ethics and informed consent procedures remain unresolved. The authors were informed of this Expression of Concern.

Pressure injuries represent a significant public health challenge in the context of global population aging. As China faces rapid aging, the characteristics of its disease burden and the strategies for prevention and control remain unclear. This study analyses the trends in the disease burden of pressure injuries in China over the past 30 years, based on the Global Burden of Disease (GBD) 2021 data, and predicts the future trends over the next 20 years. The GBD 2021 data were used in combination with the Joinpoint regression model, age-period-cohort (APC) model and Bayesian age-period-cohort (BAPC) model to analyse the burden of pressure injuries in China from 1990 to 2021 and forecast trends from 2022 to 2040. Additionally, decomposition analysis was performed to quantify the contribution of population aging to the disease burden. In 2021, the number of people with pressure injuries in China was 102 938.9, the number of new cases was 397 312.3, the disability-adjustede life years (DALYs) totaled 27 383.5 and the number of deaths was 3131.5. The gender difference was characterised by ‘higher prevalence in middle-aged men, with a reversal in very old women’. Between 1990 and 2021, the burden of pressure injuries significantly increased, with population aging being the main driving factor (46.5%–65.0%). The cohort effect indicated a higher risk for those born before 1942 (RR = 1.04–1.86), and a decreasing risk for those born after 1960 (RR = 0.91). Future projections suggest a 25.8% decrease in total cases, but an increased burden in those aged 85 and older, with deaths rising by 127%. This study highlights the aging-driven burden of pressure injuries in China, along with gender differences and typical period and cohort effects. As the population ages, the burden of pressure injuries in older age groups will continue to rise. The findings provide evidence for the ‘Healthy China 2030’ initiative and call for the inclusion of pressure injury prevention and control in the core agenda of national aging governance.

Needling therapy may be a novel alternative therapeutic intervention for burn injuries and related complications. This scoping review aimed to comprehensively evaluate the evidence status of needling therapy for burns and their complications. Studies on needling therapy for burns and related complications were retrieved from inception to 1st June 2024. Nine databases (MEDLINE, Embase, CENTRAL, CNKI, CiNii, RISS, KISS, DBpia and OASIS) were searched without any language or study-type restrictions. The study design, details of the needling therapy, and results of needling for burn injuries (or related complications) were evaluated. Of the 1475 articles screened, 46 studies (comprising 16 experimental studies, 12 case studies, four observational studies, 13 randomised controlled trials, and one systematic review) were included in the final analysis. Most studies (71.7%) investigated the acute-phase burn wound healing process, while the remaining studies (28.3%) focused on the modulation of burn-related complications. Experimental studies demonstrated that needling therapy activates phases of the wound healing process including the inflammation, proliferation, and remodelling phases and modulates the cholinergic anti-inflammatory response in burn-related acute symptoms. Clinical studies exhibited a significant heterogeneity regarding treatment period, patient population, and needling type across different study designs. Experimental studies have primarily focused on the wound healing process itself, whereas clinical studies have investigated short-term outcomes related to burn complications, with great heterogeneity observed in the methods of needling employed. Further studies are required to strengthen research gaps between experimental and clinical research, with proper treatment and evaluation periods to demonstrate the effectiveness of needling therapy for burns and associated complications.

Trial Registration: INPLASY202450102

L. Yu, Y. Wang, D. Ma, et al., “In-Hospital Nursing Care Intervention Increasing the Effect of Vacuum Sealing Drainage on Wound Healing: A Meta-Analysis,” International Wound Journal 20, no. 8 (2023): 3371–3379, https://doi.org/10.1111/iwj.14169.

In the Results section, the sentence “Then, the rest of 92 studies were checked, and 47 studies were excluded for their irrelevancy to our study objective” was incorrect. It should have been: “Then, the rest of 92 studies were checked, and 69 studies were excluded for their irrelevancy to our study objective.”

We apologise for this error.

The aim in this human trial is to compare the efficacy and safety of polygalacturonic–caprylic acid (PG–CAP) ointment to MediHoney in chronic wounds at three international medical centres. In this prospective open-label study, patients with chronic full-thickness wounds were randomised to daily treatment with PG–CAP ointment or MediHoney. Assessments were obtained weekly for 6 weeks. The validated Pressure Ulcer Scale for Healing (PUSH) score was used to track healing. Efficacies were compared using the Wilcoxon rank-sum test for continuous variables and chi-square or Fisher's exact test for categorical variables. Twenty-six patients with chronic wounds were included. Baseline characteristics were comparable between the groups; however, the history of diabetes mellitus was higher in the PG–CAP group (p = 0.011). All 13 PG–CAP patients showed improvement (100%), compared to only 69% of the 13 MediHoney patients (p = 0.023). Half of the failures in the MediHoney arm were associated with death (15%). No failures, adverse events or deaths occurred in the PG–CAP arm. PG–CAP wound ointment is a novel combination of two plant-based compounds that pose minimal risk of promoting antimicrobial resistance, was highly effective for eradicating wound-pathogen biofilms in vitro and promoted chronic wound healing in vivo with minimal inflammatory reactions. Our findings support PG–CAP as safe, noninferior and possibly more effective than MediHoney in healing chronic contaminated wounds.

Pressure injuries (PI) acquired during surgical procedures remain a serious and under-recognised patient safety concern. Operating room nurses play a critical role in PI prevention; however, their knowledge and attitudes towards preventive practices are often suboptimal and under-explored in the literature. This study aimed to assess the knowledge and attitudes of operating room nurses towards PI prevention and to examine the relationship between the two. This descriptive cross-sectional study included 208 operating room nurses from a city hospital in Istanbul, Turkey, between December 2022 and February 2023. Data were collected using the Modified Pieper Pressure Ulcer Knowledge Test (MPPUKT) and the Attitude Towards Pressure Ulcer Prevention Scale (APUP). Descriptive statistics, Pearson correlation and linear regression analyses were performed using SPSS 25.0. The mean MPPUKT score was 26.63 ± 12.43 (54.5%), with 56.7% of participants scoring below 60%, indicating inadequate knowledge. The lowest subscale scores were observed in staging (44.3%) and wound diagnostics (51.4%). In contrast, the mean APUP score was 38.33 ± 5.38, indicating a generally positive attitude, with the highest scores in the Priority and Impact subdimensions. A moderate, significant positive correlation was found between knowledge and attitude (r = 0.275, p < 0.001). Linear regression analysis confirmed that knowledge significantly predicted attitude scores (β = 0.275, p < 0.001), explaining 7.6% of the variance (R² = 0.076). While operating room nurses exhibit positive attitudes towards PI prevention, their knowledge—particularly in staging and wound assessment—is insufficient. Structured, competency-based educational programmes focusing on high-risk areas may enhance nurses' knowledge and foster more proactive preventive behaviours. Hospital systems should prioritise recurrent training and supportive strategies to promote evidence-based PI prevention practices in surgical settings.

Assessing and treating a patient's wound is something that every medical student may be faced with from day one of their postgraduate clinical career, regardless of their chosen field of specialisation. This includes acute or post-surgical wounds as well as chronic wounds. In contrast, learning content concerning wound care is currently underrepresented in medical school curricula, although there are many possible topics and options to incorporate this subject into medical teaching. As a first step in curriculum development, this study provides a comprehensive yet clinically relevant catalogue of possible learning objectives for medical students in wound care. An interprofessional and interdisciplinary group of wound care experts collected a first draft of learning objectives. Then a group of clinicians from 16 different medical specialties was consulted to additionally rate the relevance of each proposed learning objective. By this approach, a consensus catalogue of 32 relevant learning objectives in wound care for medical students was developed. Furthermore, varying perspectives of experts and clinicians on wound care topics and their relevance for medical students were identified. The findings of this study will facilitate future discussions about implementation of wound care content into medical curricula.

The study aimed to translate the PUKAT 2.0 tool from English to Italian. This was an adaptation and validation study; the validity of the Italian version was determined through content validity, item validity and construct validity. The reliability of the instrument was assessed by conducting a test–retest analysis on a sample of 62 nurses. The I-CVI indices were above the threshold of 0.78 for 91% of the questions, and according to the S-CVI index, 96% of the evaluators agreed that the questionnaire was highly relevant. The overall values for item difficulty were good, with two items being too difficult and none being too easy. The item discriminant index was overall good and reasonable, low for four items. The overall ICC was poor to moderate with a value of 0.48 (95% CI 0.26–0.65). The instrument has proven to be a good starting point although not yet completely reliable, as it clearly requires more basic preparation on the part of the staff, further modifications regarding the reliability and clarity of the questions and more training of the nursing staff if it is to be used in the Italian context.