{"title":"Delayed emergence with remimazolam after laparoscopic subsegmental hepatectomy including the intermittent pringle maneuver in a patient with preserved liver function.","authors":"Reina Miyazaki, Satoru Sekiya, Hiromu Okano, Shunsaku Goto, Hiroshi Okamoto","doi":"10.1186/s40981-026-00847-7","DOIUrl":"10.1186/s40981-026-00847-7","url":null,"abstract":"","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":"12 1","pages":"12"},"PeriodicalIF":1.0,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12873038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146118537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Lumbar disc herniation often causes disabling radicular pain and impaired quality of life (QOL). Disc-FX and L'DISQ are minimally invasive percutaneous disc decompression devices, but their comparative efficacy remains uncertain.
Methods: We retrospectively reviewed adults with single-level lumbar disc herniation treated with Disc-FX or L'DISQ at a single centre (October 2018-August 2023). Eligibility required radicular pain consistent with magnetic resonance imaging and either positive provocative discography or pain relief after intradiscal injection. Pain intensity (Numerical Rating Scale [NRS]) and QOL (EuroQOL 5-Dimension 5-Levels [EQ-5D-5 L]) were assessed at baseline and up to 6 months. The primary outcome was the between-group difference in change in NRS from baseline to 6 months. Secondary outcomes included 6-month change in EQ-5D-5 L and minimal clinically important difference (MCID) attainment (NRS ≥ 2-point reduction; EQ-5D-5 L ≥ 0.08 increase).
Results: Forty-two patients were included (Disc-FX n = 16; L'DISQ n = 26). Both procedures reduced NRS pain scores over 6 months, and the primary outcome showed no statistically significant between-group difference (mean difference 1.32 points; 95% CI - 0.36 to 3.01). Among patients with baseline EQ-5D-5 L data (n = 38), Disc-FX showed greater 6-month EQ-5D-5 L improvement (mean difference 0.134; 95% CI 0.013 to 0.255) and higher EQ-5D-5 L MCID attainment (83.3% vs. 50.0%), but these are secondary results from a small retrospective cohort.
Conclusions: In this pilot study, Disc-FX and L'DISQ had comparable short-term pain outcomes. Any apparent QOL advantage with Disc-FX should be interpreted cautiously as exploratory and potentially confounded, and requires confirmation in adequately powered prospective comparative studies.
{"title":"Evaluation of Disc-FX versus L'DISQ for percutaneous disc decompression: pilot comparative study using the minimal clinically important difference.","authors":"Haruka Takaoka, Reon Kobayashi, Ichiro Okano, Asae Taketomi, Eiko Hara, Hitoshi Mera, Masaki Ishikawa, Yoshifumi Kudo, Katsunori Oe","doi":"10.1186/s40981-026-00846-8","DOIUrl":"10.1186/s40981-026-00846-8","url":null,"abstract":"<p><strong>Background: </strong>Lumbar disc herniation often causes disabling radicular pain and impaired quality of life (QOL). Disc-FX and L'DISQ are minimally invasive percutaneous disc decompression devices, but their comparative efficacy remains uncertain.</p><p><strong>Methods: </strong>We retrospectively reviewed adults with single-level lumbar disc herniation treated with Disc-FX or L'DISQ at a single centre (October 2018-August 2023). Eligibility required radicular pain consistent with magnetic resonance imaging and either positive provocative discography or pain relief after intradiscal injection. Pain intensity (Numerical Rating Scale [NRS]) and QOL (EuroQOL 5-Dimension 5-Levels [EQ-5D-5 L]) were assessed at baseline and up to 6 months. The primary outcome was the between-group difference in change in NRS from baseline to 6 months. Secondary outcomes included 6-month change in EQ-5D-5 L and minimal clinically important difference (MCID) attainment (NRS ≥ 2-point reduction; EQ-5D-5 L ≥ 0.08 increase).</p><p><strong>Results: </strong>Forty-two patients were included (Disc-FX n = 16; L'DISQ n = 26). Both procedures reduced NRS pain scores over 6 months, and the primary outcome showed no statistically significant between-group difference (mean difference 1.32 points; 95% CI - 0.36 to 3.01). Among patients with baseline EQ-5D-5 L data (n = 38), Disc-FX showed greater 6-month EQ-5D-5 L improvement (mean difference 0.134; 95% CI 0.013 to 0.255) and higher EQ-5D-5 L MCID attainment (83.3% vs. 50.0%), but these are secondary results from a small retrospective cohort.</p><p><strong>Conclusions: </strong>In this pilot study, Disc-FX and L'DISQ had comparable short-term pain outcomes. Any apparent QOL advantage with Disc-FX should be interpreted cautiously as exploratory and potentially confounded, and requires confirmation in adequately powered prospective comparative studies.</p>","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":" ","pages":"14"},"PeriodicalIF":1.0,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145951943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Increase in the end-tidal carbon dioxide concentration during mediastinoscopic esophagectomy: a comment to a report of Haraguchi et al.","authors":"Katsuhide Masui, Tomoyuki Saito, Takero Arai, Takashi Asai","doi":"10.1186/s40981-025-00837-1","DOIUrl":"10.1186/s40981-025-00837-1","url":null,"abstract":"","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":"12 1","pages":"4"},"PeriodicalIF":1.0,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12779863/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145911484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Self-reported poor sleep quality on the day of delivery is a potential risk factor for postpartum depression after cesarean delivery: a retrospective cohort study.","authors":"Kaede Watanabe, Shohei Noguchi, Yuki Shiko, Daisuke Sakamaki, Yohei Kawasaki, Yusuke Mazda","doi":"10.1186/s40981-025-00833-5","DOIUrl":"10.1186/s40981-025-00833-5","url":null,"abstract":"","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":"11 1","pages":"70"},"PeriodicalIF":1.0,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12748453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145856281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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