S. Imad, Tahir Rafique, Shagufta A. Shaikh, S. Shafiq, Munazza Sohail
Soil chemical properties, such as Carbon and Nitrogen levels, are crucial for fulfilling the basic needs of plants. The presence of secondary and tertiary nutrients plays a vital role in constructing soil structure, influencing the survival of normal microbial flora, seeds, and later plant growth. The use of chemical fertilizers addresses nutritional deficiencies, but reports indicate that only 40% is utilized by plants, leading to soil issues like salinity and drought logging. When soil lacks essential nutrients, external amendments are necessary, impacting plant growth and crop yield by enhancing normal microbial flora i.e. Plant growth-promoting rhizobacteria (PGPRs). Recognizing the significance of both chemical nutrients and physical properties for healthy plant growth, a soil amendment called "Fertisol soil" was developed. This involved adding basic and secondary nutrients to the soil. The amended soil underwent analytical characterization and was compared with natural soil through chemical analysis and microbial growth assessments. Comparative studies using the amended soil showed improved plant growth and flowering capacity compared to control plants in terms of height and flowering. This highlights the positive impact of balanced nutrient amendments on soil health and overall plant performance.
{"title":"Significant Effect Of Amended Soil On Microbial Flora Of Soil And Plant Growth In Comparison With Natural Low Nutritive Soil","authors":"S. Imad, Tahir Rafique, Shagufta A. Shaikh, S. Shafiq, Munazza Sohail","doi":"10.24297/jac.v20i.9586","DOIUrl":"https://doi.org/10.24297/jac.v20i.9586","url":null,"abstract":"Soil chemical properties, such as Carbon and Nitrogen levels, are crucial for fulfilling the basic needs of plants. The presence of secondary and tertiary nutrients plays a vital role in constructing soil structure, influencing the survival of normal microbial flora, seeds, and later plant growth. The use of chemical fertilizers addresses nutritional deficiencies, but reports indicate that only 40% is utilized by plants, leading to soil issues like salinity and drought logging. When soil lacks essential nutrients, external amendments are necessary, impacting plant growth and crop yield by enhancing normal microbial flora i.e. Plant growth-promoting rhizobacteria (PGPRs). Recognizing the significance of both chemical nutrients and physical properties for healthy plant growth, a soil amendment called \"Fertisol soil\" was developed. This involved adding basic and secondary nutrients to the soil. The amended soil underwent analytical characterization and was compared with natural soil through chemical analysis and microbial growth assessments. Comparative studies using the amended soil showed improved plant growth and flowering capacity compared to control plants in terms of height and flowering. This highlights the positive impact of balanced nutrient amendments on soil health and overall plant performance.","PeriodicalId":14904,"journal":{"name":"JOURNAL OF ADVANCES IN CHEMISTRY","volume":"85 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141002472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The paper describes the results of the research of some heptylalkanoyldisulfides as antimicrobial additives to the lubricating oils. Heptylalkanoyldisulfides were synthesized and studied. The synthesized compounds were characterized by spectroscopic techniques. Study of antimicrobial properties of the studied heptylalkanoyldisulfides revealed effective bactericidal and fungicidal activities in suppression of fungi and bacteria allowing them to be used as biocides in storage and transportation of oil products. Antimicrobial efficacy of the studied compounds was determined by zonal diffusion method using the following microorganisms: bacteria, fungi and yeast. The test compounds were added to M-8 oil in mass percent. It is established that their antimicrobial activity is at the level of effectiveness of the widely used industrial additive sodium pentachlorophenolate. Sodium pentachlorophenolate, widely applied as an antimicrobial additive in lubricating oils, was used for comparison. It was determined that they may be used as antimicrobial additives for M-8 engine oil (0.25-1%). As a result of the studies carried out on heptylalkanoyldisulfides, distinct patterns of dependence of antimicrobial efficacy on the structure of alkyl radical were determined. Antimicrobial activity increases by an increase in alkyl radical, i.e., each subsequent member of the disulfide series is biologically more active than the previous one. The increase in antimicrobial activity seems to be due to the fact that the adding each new CH2 group gives one more van der Waals bond, increasing adsorption forces that bind the compound to the receptor in the microorganism. As a result of the studies carried out on heptylalkanoyldisulfides, distinct patterns of dependence of antimicrobial efficacy on the structure of alkyl radical were determined
{"title":"Synthesis of Heptylalkanoyldisulfides and Investigation of Their Antimicrobial Properties","authors":"Fuad Aliyev, Sara Azizova","doi":"10.24297/jac.v19i.9479","DOIUrl":"https://doi.org/10.24297/jac.v19i.9479","url":null,"abstract":"The paper describes the results of the research of some heptylalkanoyldisulfides as antimicrobial additives to the lubricating oils. Heptylalkanoyldisulfides were synthesized and studied. The synthesized compounds were characterized by spectroscopic techniques. Study of antimicrobial properties of the studied heptylalkanoyldisulfides revealed effective bactericidal and fungicidal activities in suppression of fungi and bacteria allowing them to be used as biocides in storage and transportation of oil products. Antimicrobial efficacy of the studied compounds was determined by zonal diffusion method using the following microorganisms: bacteria, fungi and yeast. The test compounds were added to M-8 oil in mass percent. It is established that their antimicrobial activity is at the level of effectiveness of the widely used industrial additive sodium pentachlorophenolate. Sodium pentachlorophenolate, widely applied as an antimicrobial additive in lubricating oils, was used for comparison. It was determined that they may be used as antimicrobial additives for M-8 engine oil (0.25-1%). As a result of the studies carried out on heptylalkanoyldisulfides, distinct patterns of dependence of antimicrobial efficacy on the structure of alkyl radical were determined. Antimicrobial activity increases by an increase in alkyl radical, i.e., each subsequent member of the disulfide series is biologically more active than the previous one. The increase in antimicrobial activity seems to be due to the fact that the adding each new CH2 group gives one more van der Waals bond, increasing adsorption forces that bind the compound to the receptor in the microorganism. As a result of the studies carried out on heptylalkanoyldisulfides, distinct patterns of dependence of antimicrobial efficacy on the structure of alkyl radical were determined","PeriodicalId":14904,"journal":{"name":"JOURNAL OF ADVANCES IN CHEMISTRY","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135436348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A new coated-wire electrode based on PVC membrane plasticized with dioctyl phthalate (DOP) and containing the diltiazem-tetraiodido bismuthate (III) ion association coated on a silver wire was constructed and used for potentiometric determination of diltiazem hydrochloride. The electrode performance was characterized and optimized according to the following experimental criteria: membrane composition, soaking time, working pH range, and response time. The interference caused by different species was investigated as well. The best membrane composition was found to be 49.75% of PVC and DOP, 0.5% ion pair. This sensor showed a linear response with a good Nernstian slope of 57.60±1.38 mV/decade over the concentration range5.0×10-5 – 2.50×10-2 M, the detection limit was 2.88×10-5 M, and it was usable within a wide pH range of 2.5–8.0. The electrode showed a fast response time (18 sec), with a relative long lifetime (2.4 months, 2 h a day). The isothermal coefficient (dE°/dT) of the electrode was calculated and found to be 5.36×10-4 V/℃ within 20 – 80℃, which exhibits a good thermal stability. The coted-wire electrode was successfully applied for the potentiometric determination of diltiazem hydrochloride both in pure form and pharmaceutical preparations. The dissolution test of the drug was carried out as well.
{"title":"Diltiazem-tetraiodide bismuthate (III) based PVC membrane for selective determination of diltiazem hydrochloride","authors":"Ryad Kassab, Mahmoud Aboudan","doi":"10.24297/jac.v19i.9378","DOIUrl":"https://doi.org/10.24297/jac.v19i.9378","url":null,"abstract":"A new coated-wire electrode based on PVC membrane plasticized with dioctyl phthalate (DOP) and containing the diltiazem-tetraiodido bismuthate (III) ion association coated on a silver wire was constructed and used for potentiometric determination of diltiazem hydrochloride. The electrode performance was characterized and optimized according to the following experimental criteria: membrane composition, soaking time, working pH range, and response time. The interference caused by different species was investigated as well. The best membrane composition was found to be 49.75% of PVC and DOP, 0.5% ion pair. This sensor showed a linear response with a good Nernstian slope of 57.60±1.38 mV/decade over the concentration range5.0×10-5 – 2.50×10-2 M, the detection limit was 2.88×10-5 M, and it was usable within a wide pH range of 2.5–8.0. The electrode showed a fast response time (18 sec), with a relative long lifetime (2.4 months, 2 h a day). The isothermal coefficient (dE°/dT) of the electrode was calculated and found to be 5.36×10-4 V/℃ within 20 – 80℃, which exhibits a good thermal stability. The coted-wire electrode was successfully applied for the potentiometric determination of diltiazem hydrochloride both in pure form and pharmaceutical preparations. The dissolution test of the drug was carried out as well.","PeriodicalId":14904,"journal":{"name":"JOURNAL OF ADVANCES IN CHEMISTRY","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82760591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wave particle duality is a cornerstone of quantum chemistry and quantum mechanics (QM). But there are experiments it cannot explain, such as a neutron interferometer experiment. If QM uses Ψ as its wavefunction, several experiments suggest that nature uses -Ψ instead. The difference between -Ψ and +Ψ is that they describe entirely different pictures of how nature is organized. For example, with -Ψ quantum particles follow waves backwards, which is incompatible with wave-particle-duality, obviously. We call the -Ψ proposal the Theory of Elementary Waves (TEW). It unlocks opportunities for young scientists with no budget to conduct the basic research for a new, unexplored science. This is a dream come true for young scientists: the discovery of uncharted territory. We show how TEW explains the double slit, Pfleegor Mandel and Davisson Germer experiments, Feynman diagrams and the Bell test experiments. We provide innovative research designs for which -Ψ and +Ψ would predict divergent outcomes. What makes QM so accurate is its probability predictions. But Born’s law would yield the same probabilities if it were changed from P = |+Ψ |2 to P = |-Ψ |2. This article is accompanied by a lively YouTube video, “6 reasons to discard wave particle duality.”
{"title":"Six Reasons to Discard Wave Particle Duality: Thereby Opening New Territory for Young Scientists to Explore","authors":"Jeffrey H. Boyd","doi":"10.24297/JAC.V18I.8948","DOIUrl":"https://doi.org/10.24297/JAC.V18I.8948","url":null,"abstract":"Wave particle duality is a cornerstone of quantum chemistry and quantum mechanics (QM). But there are experiments it cannot explain, such as a neutron interferometer experiment. If QM uses Ψ as its wavefunction, several experiments suggest that nature uses -Ψ instead. The difference between -Ψ and +Ψ is that they describe entirely different pictures of how nature is organized. For example, with -Ψ quantum particles follow waves backwards, which is incompatible with wave-particle-duality, obviously. We call the -Ψ proposal the Theory of Elementary Waves (TEW). It unlocks opportunities for young scientists with no budget to conduct the basic research for a new, unexplored science. This is a dream come true for young scientists: the discovery of uncharted territory. We show how TEW explains the double slit, Pfleegor Mandel and Davisson Germer experiments, Feynman diagrams and the Bell test experiments. We provide innovative research designs for which -Ψ and +Ψ would predict divergent outcomes. What makes QM so accurate is its probability predictions. But Born’s law would yield the same probabilities if it were changed from P = |+Ψ |2 to P = |-Ψ |2. This article is accompanied by a lively YouTube video, “6 reasons to discard wave particle duality.”","PeriodicalId":14904,"journal":{"name":"JOURNAL OF ADVANCES IN CHEMISTRY","volume":"92 1","pages":"1-29"},"PeriodicalIF":0.0,"publicationDate":"2021-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83792912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Simple and rapid spectrophotometric method for the quantitative analysis of Pitavastatin calcium (PTV) in raw material and tablets pharmaceutical formulation has been described. The method is based on the formation of yellow ion-pair complex between Pitavastatin calcium and Bromocresol purple (BCP) in chloroform medium. Different parameters affecting the reaction such as: effect of solvents, stability, reagent concentration, correlation ratio, etc. were optimized. The formed complex was quantified spectrophotometrically at absorption maximum 405 nm. Linearity range was 2.20 - 35.23 µg/mL, regression analysis showed a good correlation coefficient R2 = 0.9991. The limit of detection (LOD) and limit of quantification (LOQ) were to be 0.367 µg/mL and 1.112 µg/mL respectively. The average percent recovery was found to be (100.62 – 101.14) % for Pitavastatin Calcium. This study was applied on Syrian pharmaceutical trademark: (PAVACRIUM 4 & Londalop). The method was successfully applied for the determination of Pitavastatin calcium in tablets pharmaceutical formulation. The proposed method is simple, direct, sensitive and do not require any extraction process. Thus, this method could be readily applicable for the quality control and routine analysis.
{"title":"Determination of Pitavastatin Calcium by Analytical Spectrophotometry","authors":"S. Antakli, L. Nejem, Ahmad Kullah","doi":"10.24297/jac.v18i.8964","DOIUrl":"https://doi.org/10.24297/jac.v18i.8964","url":null,"abstract":"Simple and rapid spectrophotometric method for the quantitative analysis of Pitavastatin calcium (PTV) in raw material and tablets pharmaceutical formulation has been described. The method is based on the formation of yellow ion-pair complex between Pitavastatin calcium and Bromocresol purple (BCP) in chloroform medium. Different parameters affecting the reaction such as: effect of solvents, stability, reagent concentration, correlation ratio, etc. were optimized. The formed complex was quantified spectrophotometrically at absorption maximum 405 nm. Linearity range was 2.20 - 35.23 µg/mL, regression analysis showed a good correlation coefficient R2 = 0.9991. The limit of detection (LOD) and limit of quantification (LOQ) were to be 0.367 µg/mL and 1.112 µg/mL respectively. The average percent recovery was found to be (100.62 – 101.14) % for Pitavastatin Calcium. This study was applied on Syrian pharmaceutical trademark: (PAVACRIUM 4 & Londalop). The method was successfully applied for the determination of Pitavastatin calcium in tablets pharmaceutical formulation. The proposed method is simple, direct, sensitive and do not require any extraction process. Thus, this method could be readily applicable for the quality control and routine analysis.","PeriodicalId":14904,"journal":{"name":"JOURNAL OF ADVANCES IN CHEMISTRY","volume":"120 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88307251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Simple and rapid spectrophotometric method was developed and applied to determine Glibenclamide (GB) by zero spectrophotometric method and first derivative spectrophotometric method for determining of (GB) in the presence of Metformin hydrochloride (MET). Zero spectrophotometric (ZS) method was applied for the determination of (GB) at λmax = 300 nm. Linearity range was (4 – 360) μg/mL. Regression analysis showed a good correlation coefficients R2 = 0.99993. The limit of detection (LOD) and limit of quantification (LOQ) were to be 0.65 μg/mL and 2.31 μg/mL, respectively. First derivative spectrophotometric (1DS) method was applied for the determination of (GB) in the presence (MET). (GB) was determined at 317 nm (1D317). Linearity ranges were (4 – 240) μg/mL for (GB). Regression analysis showed a good correlation coefficients R2 = 0.999914. The limit of detection (LOD) and limit of quantification (LOQ) were to be 0.60 μg/mL and 1.83 μg/mL for (GB). The proposed zero spectrophotometry method was applied to analysis individual (GB), and the derivative (1D317) method was applied to analysis (GB) individually or combined with (MET) in Syrian trademark drugs. The proposed method is simple, direct, sensitive and do not require any extraction process. Thus, this method could be readily applicable for the quality control and routine analysis.
{"title":"Determination of Glibenclamide By Analytical Spectrophotometry","authors":"S. Antakli, L. Nejem, Monzer Alraii","doi":"10.24297/jac.v18i.8963","DOIUrl":"https://doi.org/10.24297/jac.v18i.8963","url":null,"abstract":"Simple and rapid spectrophotometric method was developed and applied to determine Glibenclamide (GB) by zero spectrophotometric method and first derivative spectrophotometric method for determining of (GB) in the presence of Metformin hydrochloride (MET). Zero spectrophotometric (ZS) method was applied for the determination of (GB) at λmax = 300 nm. Linearity range was (4 – 360) μg/mL. Regression analysis showed a good correlation coefficients R2 = 0.99993. The limit of detection (LOD) and limit of quantification (LOQ) were to be 0.65 μg/mL and 2.31 μg/mL, respectively. First derivative spectrophotometric (1DS) method was applied for the determination of (GB) in the presence (MET). (GB) was determined at 317 nm (1D317). Linearity ranges were (4 – 240) μg/mL for (GB). Regression analysis showed a good correlation coefficients R2 = 0.999914. The limit of detection (LOD) and limit of quantification (LOQ) were to be 0.60 μg/mL and 1.83 μg/mL for (GB). The proposed zero spectrophotometry method was applied to analysis individual (GB), and the derivative (1D317) method was applied to analysis (GB) individually or combined with (MET) in Syrian trademark drugs. The proposed method is simple, direct, sensitive and do not require any extraction process. Thus, this method could be readily applicable for the quality control and routine analysis.","PeriodicalId":14904,"journal":{"name":"JOURNAL OF ADVANCES IN CHEMISTRY","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78013542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A consensus among quantum experts is that the quantum world is not properly understood. It is a mistake to think we can cure quantum weirdness by tinkering with superficial aspects of quantum mechanics (QM). We propose that nature uses (–ψ) as its wave function, whereas QM uses (+ψ). We propose therefore that the Periodical Table should be changed to negative orbitals (–ψ). Surprisingly, this change makes almost no difference to chemistry on a practical level. The Born rule takes the absolute square of an amplitude to obtain a probability to test in chemistry lab P=|–ψ|2=|+ψ|2. We propose a new math based on (–ψ) that is the mirror image of quantum mathematics. We call it the Theory of Elementary Waves (TEW). The negative sign is not an electrical charge. It has nothing to do with Coulomb’s law. Valence electrons are unchanged. Ions, covalent bonds, dipoles, metals, hydrogen bonding and the hydrogen 21 cm line are unchanged. The octet rule and rules for drawing dot structures of molecules do not change. Amino acids, sugars and DNA do not change their handedness. We cite abundant experimental evidence showing that TEW is correct and QM is wrong.
{"title":"The Periodic Table needs negative orbitals in order to eliminate quantum weirdness: a new quantum chemistry mathematics","authors":"Jeffrey H. Boyd","doi":"10.24297/jac.v17i.8865","DOIUrl":"https://doi.org/10.24297/jac.v17i.8865","url":null,"abstract":"A consensus among quantum experts is that the quantum world is not properly understood. It is a mistake to think we can cure quantum weirdness by tinkering with superficial aspects of quantum mechanics (QM). We propose that nature uses (–ψ) as its wave function, whereas QM uses (+ψ). We propose therefore that the Periodical Table should be changed to negative orbitals (–ψ). Surprisingly, this change makes almost no difference to chemistry on a practical level. The Born rule takes the absolute square of an amplitude to obtain a probability to test in chemistry lab P=|–ψ|2=|+ψ|2. We propose a new math based on (–ψ) that is the mirror image of quantum mathematics. We call it the Theory of Elementary Waves (TEW). The negative sign is not an electrical charge. It has nothing to do with Coulomb’s law. Valence electrons are unchanged. Ions, covalent bonds, dipoles, metals, hydrogen bonding and the hydrogen 21 cm line are unchanged. The octet rule and rules for drawing dot structures of molecules do not change. Amino acids, sugars and DNA do not change their handedness. We cite abundant experimental evidence showing that TEW is correct and QM is wrong.","PeriodicalId":14904,"journal":{"name":"JOURNAL OF ADVANCES IN CHEMISTRY","volume":"60 1","pages":"88-125"},"PeriodicalIF":0.0,"publicationDate":"2020-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83607156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The derivative spectrophotometric method was developed and applied for the simultaneous determination of Atenolol (ATE) and Hydrochlorothiazide (HCT) in Tablets formulations. The first derivative spectrophotometric (1DS) method was applied for the determination of (ATE) and (HCT), respectively. (ATE) was determined at 271.9 nm (1D 271.9) and (HCT) was determined at 279.3 nm (1D 279.3). Linearity showed a good correlation coefficients R2 = 0.9994 and R2 = 0.9989 for (ATE) and (HCT), respectively. Linearity ranges were (10 – 280)
{"title":"Simultaneous Determination Of Atenolol And Hydrocholrothiazide In Tablets Formulation By Derivative Spectrometry","authors":"S. Antakli, L. Nejem, Moustafa Alabo Joumaa","doi":"10.24297/jac.v17i.8808","DOIUrl":"https://doi.org/10.24297/jac.v17i.8808","url":null,"abstract":"The derivative spectrophotometric method was developed and applied for the simultaneous determination of Atenolol (ATE) and Hydrochlorothiazide (HCT) in Tablets formulations. The first derivative spectrophotometric (1DS) method was applied for the determination of (ATE) and (HCT), respectively. (ATE) was determined at 271.9 nm (1D 271.9) and (HCT) was determined at 279.3 nm (1D 279.3). Linearity showed a good correlation coefficients R2 = 0.9994 and R2 = 0.9989 for (ATE) and (HCT), respectively. Linearity ranges were (10 – 280)","PeriodicalId":14904,"journal":{"name":"JOURNAL OF ADVANCES IN CHEMISTRY","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85927134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
First simple spectrophotometric method was developed and applied to determine Dapagliflozin Propanediol Monohydrate by Zero Spectrophotometry and First Derivative Spectrophotometric method for determining of Dapagliflozin Propanediol Monohydrate (DAPA) in the presence of Metformin Hydrochloride (MET). Zero spectrophotometric (ZS) was applied for the determination of (DAPA) at 223.5 nm. Linearity range was (2.61– 31.23) µg/mL. Regression analysis showed a good correlation coefficients R2 = 0.9989. The limit of detection (LOD) and limit of quantification (LOQ) were to be 0.569 µg/mL and 1.724 µg/mL, respectively. Derivative spectrophotometric (1DS) was applied for the determination of (DAPA) in the presence (MET). (DAPA) was determined at 233 nm (1D233). Linearity ranges were (5.21 – 41.64) µg/mL for (DAPA). Regression analysis showed a good correlation coefficients R2 = 0.9994. The limit of detection (LOD) and limit of quantification (LOQ) were to be 0.732 µg/mL and 2.218 µg/mL for (DAPA). The proposed Zero spectrophotometry method was applied to analysis individual (DAPA), and the derivative (1D233) method was applied to analysis (DAPA) individually or with (MET) combination in Syrian trademark drugs.
{"title":"Analytical Spectrometric Study For Determining Dapagliflozin Propanediol Monohydrate Individually Or In Presence Of Metformin Hydrochloride In Tablets Formulation","authors":"S. Antakli, Raghad Kabbani, And Rama Labban","doi":"10.24297/jac.v17i.8812","DOIUrl":"https://doi.org/10.24297/jac.v17i.8812","url":null,"abstract":"First simple spectrophotometric method was developed and applied to determine Dapagliflozin Propanediol Monohydrate by Zero Spectrophotometry and First Derivative Spectrophotometric method for determining of Dapagliflozin Propanediol Monohydrate (DAPA) in the presence of Metformin Hydrochloride (MET). Zero spectrophotometric (ZS) was applied for the determination of (DAPA) at 223.5 nm. Linearity range was (2.61– 31.23) µg/mL. Regression analysis showed a good correlation coefficients R2 = 0.9989. The limit of detection (LOD) and limit of quantification (LOQ) were to be 0.569 µg/mL and 1.724 µg/mL, respectively. Derivative spectrophotometric (1DS) was applied for the determination of (DAPA) in the presence (MET). (DAPA) was determined at 233 nm (1D233). Linearity ranges were (5.21 – 41.64) µg/mL for (DAPA). Regression analysis showed a good correlation coefficients R2 = 0.9994. The limit of detection (LOD) and limit of quantification (LOQ) were to be 0.732 µg/mL and 2.218 µg/mL for (DAPA). The proposed Zero spectrophotometry method was applied to analysis individual (DAPA), and the derivative (1D233) method was applied to analysis (DAPA) individually or with (MET) combination in Syrian trademark drugs.","PeriodicalId":14904,"journal":{"name":"JOURNAL OF ADVANCES IN CHEMISTRY","volume":"194 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90659143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mukasa-Tebandeke, I. Z., Karume, I., Ssebuwufu, J., Wasajja , H. Z., Nankinga, R, Habimana, M
Pollution is affecting river Rwabakazi in the Nile basin. Its effects are reflected by high turbidity, pH, total suspended solids, (T.S.S.), electrical conductivity, metal ions concentrations, and low concentration of dissolved oxygen (DO5). In this study, we report the variations in selected physicochemical parameters of waters of the Rwabakazi river. Turbidity, pH, concentrations of selected metal ions, T.S.S., and DO5 of water sampled from three selected sites on the river in Kabale were very high. Mean DO5 fell from 96 ± 2 mg/L to 86± 1.5 mg/L downstream. The mean pH fell from 7.8 ± 0.03 to 7.6 ± 0.04, showing the removal of basic components. The turbidity dropped from370 ± 3 NTU to 305 ± 2 NTU, showing that the haziness of water decreased. The concentration of iron(II) fell from 320 ± 0.3 mg/L to 291 ± 0.2 mgL-1 indicating the fair extent of heavy metal ions downstream. The T.S.S. decreased from 330 ± 5 mg/L to 300± 5 mg/L, and concentrations of calcium and magnesium ions also decreased, providing evidence for self-purification. The available data suggests that river Rwabakazi is polluted as a result of poor agricultural practices, erosion, and flash flooding. Further studies on nutrient and pesticide pollution of this river need to be carried out, and trees should be planted on steep open surfaces to minimize erosion.
{"title":"How variations in concentrations of metal ions and suspended solids downstream river Rwabakazi in Uganda can be used to study pollution","authors":"Mukasa-Tebandeke, I. Z., Karume, I., Ssebuwufu, J., Wasajja , H. Z., Nankinga, R, Habimana, M","doi":"10.24297/jac.v17i.8767","DOIUrl":"https://doi.org/10.24297/jac.v17i.8767","url":null,"abstract":"Pollution is affecting river Rwabakazi in the Nile basin. Its effects are reflected by high turbidity, pH, total suspended solids, (T.S.S.), electrical conductivity, metal ions concentrations, and low concentration of dissolved oxygen (DO5). In this study, we report the variations in selected physicochemical parameters of waters of the Rwabakazi river. Turbidity, pH, concentrations of selected metal ions, T.S.S., and DO5 of water sampled from three selected sites on the river in Kabale were very high. Mean DO5 fell from 96 ± 2 mg/L to 86± 1.5 mg/L downstream. The mean pH fell from 7.8 ± 0.03 to 7.6 ± 0.04, showing the removal of basic components. The turbidity dropped from370 ± 3 NTU to 305 ± 2 NTU, showing that the haziness of water decreased. The concentration of iron(II) fell from 320 ± 0.3 mg/L to 291 ± 0.2 mgL-1 indicating the fair extent of heavy metal ions downstream. The T.S.S. decreased from 330 ± 5 mg/L to 300± 5 mg/L, and concentrations of calcium and magnesium ions also decreased, providing evidence for self-purification. The available data suggests that river Rwabakazi is polluted as a result of poor agricultural practices, erosion, and flash flooding. Further studies on nutrient and pesticide pollution of this river need to be carried out, and trees should be planted on steep open surfaces to minimize erosion. ","PeriodicalId":14904,"journal":{"name":"JOURNAL OF ADVANCES IN CHEMISTRY","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83004710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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