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Intravenous calcium therapy in calcium channel blocker poisoning - A double-edged sword. 钙通道阻滞剂中毒的静脉钙治疗--一把双刃剑。
IF 1.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2024-01-01 Epub Date: 2024-03-14 DOI: 10.4103/joacp.joacp_250_22
Balaji Rajaram, Rajathadri H Ravikumar, Shashikant Sharma, Puneet Khanna
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引用次数: 0
Combined interscalene brachial plexus block and superficial cervical plexus block for shoulder disarticulation surgery in a terminal cancer patient. 在一名癌症晚期患者的肩关节离断手术中联合使用椎间臂丛神经阻滞和颈浅丛神经阻滞。
IF 1.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2024-01-01 Epub Date: 2024-03-14 DOI: 10.4103/joacp.joacp_194_22
Bhavna Sriramka, Tanmaya Pradhan
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引用次数: 0
Point-of-care ultrasound (POCUS): Determination of fluid responsiveness by measuring left brachiocephalic vein diameter. 护理点超声(POCUS):通过测量左侧肱脑静脉直径确定输液反应性。
IF 1.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2024-01-01 Epub Date: 2024-03-14 DOI: 10.4103/joacp.joacp_192_22
Amarjeet Kumar, Chandni Sinha, Kunal Singh, Ajeet Kumar, Poonam Kumari
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引用次数: 0
A comparative study of key quality performance indicators in anesthesia and surgery in operation theatre at a tertiary care hospital in Rishikesh. 对瑞诗凯诗一家三级医院手术室的麻醉和手术关键质量绩效指标的比较研究。
IF 1.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2024-01-01 Epub Date: 2024-03-14 DOI: 10.4103/joacp.joacp_33_22
Bhavna Gupta, Sanjay Agrawal, Anubha Agarwal

Background and aims: A Key Performance Indicator (KPI) is a critical metric measuring organizational success or specific activities, reflecting the periodic achievement of operational goals aligned with strategic objectives.

Material and methods: A retrospective cross-sectional study of key quality performance indicators, (CQI-NABH) concerning anesthesia and surgical services was conducted at a tertiary care hospital after taking institutional ethical clearance (AIIMS/IEC/21/150). It was as per COP 13, COP 14, and COP 15 standards of NABH 4th edition published in 2015. The study was conducted at the department of anesthesiology at a tertiary care hospital, and data were retrospectively analyzed from 01 October 2019, till November 2020. All patients undergoing elective or emergency surgical procedures under monitored anesthesia care and regional or general anesthesia during the study period were considered.The primary objective was to analyze Continuous Quality Improvement (CQI) in perioperative services, with secondary goals including gap identification, suggesting corrective actions, and examining quality indicators during the COVID-19 pandemic in 2020.

Results: Out of 8574 patients operated during the study, 6705 were in the four months before the pandemic, and 1869 were operated during the COVID-19 scenario. In the pre-COVID era, many of the cases were performed on an elective basis (71.23%), and emergencies constituted 16.9% of the total number of cases. In the COVID era, most of the cases were emergencies (45.4%) and semi-emergencies (40.25%), and elective cases were only 14.05% of the total cases performed. The percentage of modification of anaesthesia plans ranged from 0-3.34%. Adverse anaesthesia events were observed in 0-2.1%, primarily related to cardiovascular, respiratory, and airway issues. No anaesthesia-related mortality was reported. Prophylactic antibiotic administration within one hour of surgery ranged from 88-100%.

Conclusions: Monitoring and evaluating healthcare performance, specifically through KPIs, is vital for optimizing care and resource utilization. These indicators provide an overview of hospital service efficiency, aiding in key areas such as patient treatment, satisfaction, healthcare quality improvement, cost reduction, and optimal resource utilization. Addressing identified issues ensures effective and sustainable quality improvement in anaesthesia services, emphasizing ongoing monitoring as a foundation for hospital quality assurance.

背景和目的:关键绩效指标(KPI)是衡量组织成功或特定活动的重要指标,反映了与战略目标一致的运营目标的定期实现情况:在获得机构伦理许可(AIIMS/IEC/21/150)后,我们在一家三级护理医院开展了一项有关麻醉和手术服务的关键质量绩效指标(CQI-NABH)的回顾性横断面研究。该研究符合 2015 年发布的 NABH 第四版 COP 13、COP 14 和 COP 15 标准。研究在一家三甲医院的麻醉科进行,并回顾性分析了从 2019 年 10 月 1 日到 2020 年 11 月的数据。研究的主要目标是分析围术期服务的持续质量改进(CQI),次要目标包括找出差距、提出纠正措施以及在2020年COVID-19大流行期间检查质量指标:在研究期间接受手术的 8574 名患者中,有 6705 名是在大流行前四个月接受手术的,1869 名是在 COVID-19 期间接受手术的。在前 COVID 时代,许多病例都是择期手术(71.23%),急诊占病例总数的 16.9%。在 COVID 时代,大部分病例为急诊(45.4%)和半急诊(40.25%),而选择性病例仅占总病例数的 14.05%。修改麻醉计划的比例在 0-3.34% 之间。麻醉不良事件发生率为 0-2.1%,主要与心血管、呼吸和气道问题有关。没有与麻醉相关的死亡率报告。手术后一小时内预防性使用抗生素的比例为88%-100%:监测和评估医疗绩效,特别是通过关键绩效指标,对于优化护理和资源利用至关重要。这些指标提供了医院服务效率的概况,有助于患者治疗、满意度、医疗质量改进、成本降低和资源优化利用等关键领域。解决已发现的问题可确保有效、可持续地提高麻醉服务质量,强调持续监测是医院质量保证的基础。
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引用次数: 0
Comparison of weight-based and pinna size method for ProSeal laryngeal mask airway size selection in children receiving general anesthesia: A randomized clinical study. 比较基于体重和耳廓尺寸的方法为接受全身麻醉的儿童选择 ProSeal 喉罩气道尺寸:随机临床研究。
IF 1.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2024-01-01 Epub Date: 2024-03-14 DOI: 10.4103/joacp.joacp_217_22
Rajesh Mishra, Ranvinder Kaur, Aditi Suri, Rupesh Yadav, Seema Wasnik

Background and aims: Several methods are in use for LMA ProSeal™ size selection in pediatric patients. Weight-based method is most commonly used. Pinna size-based method is a promising new technique for accurate size selection.

Material and methods: A total of 146 children aged between 6 months and 12 years undergoing surgery under general surgery were included. They were randomized into either pinna-based group (group X) or weight-based group (group Y). Both groups were compared for accurate placement of ProSeal™ laryngeal mask airway (PLMA), ease of insertion, number of attempts needed, and peak airway pressures.

Results: A Comparable number of patients had a Brimacombe score of 3 and above, indicating correct placement in both groups (P = 0.407). PLMA was easily inserted in 79.5% and 87.7% of patients of groups X and Y, respectively (P = 0.180). Insertion was found to be difficult in 20.5% of patients in group X, whereas it was difficult in only 12.3% of patients of group Y (P = 0.180). The two groups were comparable as per the number of attempts needed for insertion (P = 0.161). Mean peak airway pressures too were comparable between both groups. Ease of insertion too, was statistically insignificant between both groups.

Conclusions: Pinna size-based estimation of LMA size is an effective alternative method to weight-based selection.

背景和目的:有几种方法可用于选择儿科患者的 LMA ProSeal™ 大小。最常用的是基于体重的方法。基于耳廓尺寸的方法是一种很有前途的新技术,可用于准确选择尺寸:共纳入 146 名接受普外科手术的 6 个月至 12 岁儿童。他们被随机分为基于耳廓的一组(X 组)或基于体重的一组(Y 组)。两组在 ProSeal™ 喉罩通气道(PLMA)的准确置入、插入难易程度、所需尝试次数和气道峰压方面进行了比较:两组患者的 Brimacombe 评分均在 3 分及以上的人数相当,这表明两组患者均能正确放置喉罩气道(P = 0.407)。X组和Y组分别有79.5%和87.7%的患者能轻松插入PLMA(P = 0.180)。X组有20.5%的患者难以插入,而Y组仅有12.3%的患者难以插入(P = 0.180)。两组患者插入所需的尝试次数相当(P = 0.161)。两组患者的平均气道峰压也相当。两组的插入难易程度也无统计学意义:结论:基于耳廓大小估算 LMA 大小是一种有效的替代方法,可替代基于体重的选择。
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引用次数: 0
Comparison of intraoperative blood pressure values measured by noninvasive versus invasive methods during normotension, hypertension, and hypotension 正常血压、高血压和低血压时无创与有创术中血压测量值的比较
Q3 PHARMACOLOGY & PHARMACY Pub Date : 2023-10-18 DOI: 10.4103/joacp.joacp_439_22
Joel Irimpan, Rajesh Kesavan, Sunil Rajan, Lakshmi Kumar
Abstract Background and Aims: Monitoring of intraoperative blood pressure (BP) is essential. We aimed to compare BP values simultaneously recorded by invasive and noninvasive methods under general anesthesia (GA) during normotension, hypertension, and hypotension. Mean arterial pressure (MAP) values calculated by the automated technique were also compared to the values obtained using predefined formula. Material and Methods: An observational, prospective study was conducted in 250 adult patients undergoing elective surgeries under GA. Before induction, noninvasive blood pressure (NIBP) was measured in the arm in a supine position using an automated oscillometer. Radial artery in the opposite arm was cannulated. NIBP and arterial BP (ABP) were recorded simultaneously during normotension, hypotension, and hypertension. Results: During normotension and hypertension, systolic BP (SBP) measured by NIBP and ABP were comparable. Diastolic BP (DBP) and MAP during normotension were significantly higher with NIBP (73.65 ± 7.73 vs. 65.69 ± 8.39 and 87.79 ± 8.43 vs. 84.24 ± 8.82, respectively). During hypertension, DBP and MAP were significantly higher with NIBP (90.44 ± 11.61 vs. 78.59 ± 11.09 and 111.67 ± 10.43 vs. 105.63 ± 11.06, respectively). During hypotension, SBP was significantly higher in ABP (91.14 ± 6.90 vs. 86.24 ± 6.06), and DBP and MAP were comparable. Comparison of MAP measured by ABP and NIBP techniques with the MAP calculated using predefined formula in normotension showed significantly higher values with the automated technique. Conclusions: During normotension and hypertension, DBP and MAP showed significantly higher values with the NIBP technique compared to ABP, with comparable SBP values. During hypotension, SBP showed significantly higher values with the ABP technique, with comparable DBP and MAP. MAP obtained using predefined formula and automated method in normotension was significantly higher with the automated technique.
背景与目的:术中监测血压(BP)是必要的。我们的目的是比较在全身麻醉(GA)下,在正常血压、高血压和低血压期间,有创和无创方法同时记录的血压值。自动技术计算的平均动脉压(MAP)值也与使用预定义公式获得的值进行比较。材料和方法:一项观察性、前瞻性研究对250例在GA下接受择期手术的成年患者进行了研究。诱导前,在仰卧位使用自动振荡计测量手臂无创血压(NIBP)。对臂桡动脉插管。在正常血压、低血压和高血压时同时记录NIBP和动脉血压(ABP)。结果:在正常血压和高血压时,NIBP和ABP测量的收缩压(SBP)具有可比性。正常血压时舒张压(DBP)和MAP明显高于NIBP(分别为73.65±7.73 vs. 65.69±8.39和87.79±8.43 vs. 84.24±8.82)。高血压期间,DBP和MAP均明显高于NIBP(分别为90.44±11.61比78.59±11.09和111.67±10.43比105.63±11.06)。低血压时,收缩压与ABP显著升高(91.14±6.90比86.24±6.06),DBP与MAP具有可比性。用ABP和NIBP技术测量的MAP与用预定公式计算的MAP在正常血压下的比较显示,自动化技术的MAP值明显更高。结论:在正常血压和高血压期间,与ABP相比,NIBP技术显示的DBP和MAP值明显更高,收缩压值也相当。在低血压期间,ABP技术显示收缩压明显升高,DBP和MAP相当。在正常血压条件下,采用自动方法和预定义公式得到的MAP明显高于自动方法。
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引用次数: 0
Effect of operation table height on ease of mask ventilation, laryngeal view, and endotracheal intubation success 手术台高度对面罩通气、喉部观察及气管插管成功率的影响
Q3 PHARMACOLOGY & PHARMACY Pub Date : 2023-10-18 DOI: 10.4103/joacp.joacp_443_22
Mamta Jain, Kunika Tantia, Sanjay Johar, Anish Kumar Singh, Teena Bansal, Jyoti Sharma
Abstract Background and Aims: Optimal patient positioning and operating table height are essential for an ergonomic posture of an anesthesiologist in which there is minimal or no strain on thewrist during mask ventilation. It also avoids flexion of the neck, lower back, and knee bending at the time of laryngoscopy and intubation. Material and Methods One hundred eighty patients were randomly allocated to three groups based on different table heights. The height of the table is kept at the mid-sternum level of an anesthesiologist in group 1, at the xiphoid process in group 2, and at the level of umbilicus in group 3. Laryngoscopic view with or without postural changes (exertion at wrist joint, flexion of the neck, lower back, or knee bending) was graded as per Cormack Lehane’s (CL) grading. The degree of discomfort experienced by the anesthesiologist during mask ventilation or tracheal intubation was graded subjectively (1 = no discomfort, 2 = mild discomfort, 3 = moderate discomfort, and 4 = severe discomfort) at different table heights. Postural changes required to obtain the best glottic view and quality of endotracheal (ET) intubation (intubation time and attempts required) were also noted. For analysis, quantitative variables were expressed as mean ± SD and compared using unpaired t or analysis of variance test. Qualitative variables were expressed as frequencies/percentages and compared using the Chi-square test. Results with P value <0.05 were considered significant statistically. Results Moderate discomfort (strain at wrist joint) during bag–mask ventilation was experienced by the anesthesiologist in a maximum number of patients in group 1 (81.7%). Significant improvement was seen in CL grade after the use of postural modifications in groups 1 and 2 ( P value ≤0.05). Greater postural modifications were required during ET intubation at lower table heights (group 3). Conclusions: It is advisable to adopt higher table positioning in relation to anesthesiologist performing the laryngoscopy for smooth and single-attempt ET intubation since the best laryngoscopic view and intubation with minimal postural modifications was seen at higher table heights (at the mid-sternum level of an anesthesiologist).
摘要背景和目的:最佳的患者体位和手术台高度对于麻醉医师的人体工程学姿势至关重要,在面罩通气期间腕部的压力最小或没有压力。它还可以避免在喉镜检查和插管时颈部、下背部和膝盖弯曲。材料与方法180例患者根据不同的桌高随机分为3组。第1组麻醉医师将手术台高度保持在胸骨中段,第2组保持在剑突,第3组保持在脐部。根据Cormack Lehane (CL)分级,在喉镜下观察有无体位变化(手腕关节用力、颈部屈曲、下背部或膝盖弯曲)。对麻醉医师在面罩通气或气管插管时的不适程度进行主观分级(1 =无不适,2 =轻度不适,3 =中度不适,4 =严重不适)。还记录了获得最佳声门视野和气管内插管质量(插管时间和所需次数)所需的体位变化。定量变量以均数±标准差表示,采用未配对t或方差分析检验进行比较。定性变量以频率/百分比表示,并使用卡方检验进行比较。P值为<0.05为差异有统计学意义。结果麻醉医师在气囊面罩通气过程中出现中度不适(腕关节劳损)的患者最多,占81.7%。第1组和第2组采用体位改良后CL分级有显著改善(P值≤0.05)。在较低的手术台高度进行ET插管时,需要更大的体位调整(第3组)。结论:由于在较高的手术台高度(麻醉医师的胸骨中位)可以看到最佳的喉镜视野和最小体位调整,因此,与麻醉师进行顺畅的单次ET插管相比,建议采用较高的手术台位置。
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引用次数: 0
Evaluation and comparison of sonographic difficult airway assessment parameters with clinical airway predictors 超声困难气道评估参数与临床气道预测指标的评价与比较
Q3 PHARMACOLOGY & PHARMACY Pub Date : 2023-10-18 DOI: 10.4103/joacp.joacp_181_23
U Anushaprasath, Mritunjay Kumar, Manoj Kamal, Pradeep Bhatia, Narendra Kaloria, Bharat Paliwal, Sunit Kumar Gupta, Sadik Mohammed, Ankur Sharma
Abstract Background and Aims: None of the clinical difficult airway predictors are 100% sensitive and specific. Ultrasound is being used for airway assessment, but there is still no established parameters or model to predict difficult laryngoscopy. This observational study was planned to determine the predictive ability of clinical and sonography-based airway assessment parameters for difficult laryngoscopy and intubation. Material and Methods: A total of 130 patients of 18–60 years of age undergoing elective intubation were included. The distribution of Cormack–Lehane (CL) grade and intubation difficulty scale (IDS) was correlated with the clinical and sonographic screening parameters for difficult airways. Results The prevalence of difficult laryngoscopy and difficult intubation in our study was 17.6% and 11.5%, respectively. Mallampati grade (MMG), upper lip bite test (ULBT), neck circumference, hyomental distance ratio (HMDR), tongue thickness (TT), skin to epiglottis/epiglottis to vocal cord distance (SED/E-VC), and mandibular condylar mobility (MCM) had significant association with the difficult laryngoscopy and MMG, neck circumference, SED, SED/E-VC; MCM had significant association with the difficult intubation. The combination of these predictors showed better diagnostic ability for difficult airways. Model 1 based on ultrasound parameters showed an area under the curve (AUC) of 0.848 (CI- 0.748-0.947, P value < 0.0001) and model 2 based on combined clinical and ultrasound parameters showed an AUC of 0.755 (95% CI- 0.631-0.879, P value < 0.0001). Conclusions: Ultrasound-based airway predictors can help in predicting difficult laryngoscopy and intubation along with the clinical parameters. Individual sonographic predictors have moderately satisfactory diagnostic profiles. The models based on combined tests have better diagnostic value.
背景与目的:没有一种临床困难的气道预测因子是100%敏感和特异性的。超声被用于气道评估,但仍没有确定的参数或模型来预测困难的喉镜检查。本观察性研究旨在确定临床和基于超声的气道评估参数对困难喉镜检查和插管的预测能力。材料与方法:共纳入130例年龄18-60岁的择期插管患者。Cormack-Lehane (CL)分级和插管困难量表(IDS)的分布与困难气道的临床和超声筛查参数相关。结果本研究中喉镜检查和插管困难的发生率分别为17.6%和11.5%。Mallampati分级(MMG)、上唇咬合试验(ULBT)、颈围、眼膜距离比(HMDR)、舌厚(TT)、皮肤到会厌/会厌到声带距离(SED/E-VC)、下颌髁活动度(MCM)与喉镜检查困难、MMG、颈围、SED、SED/E-VC有显著相关性;MCM与插管困难有显著相关性。这些预测因子的组合显示出对困难气道的更好的诊断能力。基于超声参数的模型1曲线下面积(AUC)为0.848 (CI- 0.748 ~ 0.947, P值<0.0001),基于临床和超声综合参数的模型2的AUC为0.755 (95% CI- 0.631-0.879, P值<0.0001)。结论:基于超声的气道预测指标可以帮助预测困难的喉镜检查和插管以及临床参数。个别超声预测有中等满意的诊断概况。基于组合试验的模型具有较好的诊断价值。
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引用次数: 0
Pain as a presenting symptom of hypothyroidism 疼痛是甲状腺功能减退症的主要症状
Q3 PHARMACOLOGY & PHARMACY Pub Date : 2023-10-05 DOI: 10.4103/joacp.joacp_283_23
Nishant Kumar, Mrinal Kamal, Pramod Kohli
Abstract Chronic back or limb pain is often debilitating and disabling resulting in loss of efficiency, depression, and low self-esteem. Diagnosis usually suggests arthritis or nerve root pathology and patients receive long-term oral analgesics and invasive procedures with little or no relief. Hypothyroidism may present as peripheral neuropathy which may be clinically indistinguishable from entrapment neuropathy as occurs with neural canal stenosis. Muscle cramps, aches, proximal symmetrical muscle weakness, stiffness, polymyositis, and exercise intolerance may be the only presenting symptom indicating hypothyroidism. We present five cases of acute on chronic pain that improved significantly on treatment with thyroxine. Neuromuscular pain may be the only presenting symptom of hypothyroidism. Thyroid profile (TSH, FT3, FT4) and anti-thyroid peroxidase (anti-TPO) antibodies should be screened before subjecting the patient to multiple analgesics and procedures.
慢性背部或肢体疼痛常常使人衰弱和致残,导致工作效率下降、抑郁和自卑。诊断通常提示关节炎或神经根病变,患者接受长期口服止痛药和侵入性手术,很少或没有缓解。甲状腺功能减退可表现为周围神经病变,在临床上与神经管狭窄引起的卡压性神经病难以区分。肌肉痉挛、疼痛、近端对称肌无力、僵硬、多发性肌炎和运动不耐受可能是甲状腺功能减退的唯一表现。我们提出了5例急性和慢性疼痛显著改善治疗甲状腺素。神经肌肉疼痛可能是甲状腺功能减退症的唯一表现。在给患者使用多种镇痛药和手术前,应筛查甲状腺特征(TSH、FT3、FT4)和抗甲状腺过氧化物酶(抗tpo)抗体。
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引用次数: 0
Comparison of fascial plane blocks (ESPB vs. TPVB) for pain relief following modified radical mastectomy 改良乳房根治术后筋膜平面阻滞(ESPB与TPVB)缓解疼痛的比较
Q3 PHARMACOLOGY & PHARMACY Pub Date : 2023-10-05 DOI: 10.4103/joacp.joacp_90_23
S Jayakrishnan, Amit Dua, Alok Kumar
Abstract Background and Aims: The erector spinae plane block (ESPB) is a novel regional anesthesia technique compared to the thoracic paravertebral block (TPVB) in providing postoperative pain relief in breast surgeries. Modified radical mastectomy (MRM) is a commonly performed surgery for breast cancer. The objective of the study is to compare the efficacy of ESPB and TPVB in providing postoperative pain relief after MRM. Material and Methods: This is a prospective randomized study conducted in a tertiary care teaching hospital. Sixty ASA I–III adult patients (age >18 years) scheduled to undergo elective unilateral MRM for breast cancer were enrolled in the study. Ultrasound-guided ESPB or TPVB with 0.25% bupivacaine was performed preoperatively on the patients randomized into two groups, namely, the ESPB and TPVB groups. All patients received patient-controlled analgesia for postoperative pain relief. Morphine consumption and Visual Analog Score (VAS) for pain were recorded at 3, 6, 12, and 24 h postoperatively. Results: Primarily, the mean postoperative VAS scores between the two groups at 3, 6, 12, and 24 h showed no statistical significance and were comparable when matched at different time points. However, 24-h morphine consumption was significantly more in the ESPB group ( P = 0.035). Duration of block performance also showed a significant difference, with ESPB taking less time to perform ( P < 0.001). The mean age and body mass index (BMI) of patients and length of hospital stay in both the groups were similar. Conclusions: Both ESPB and TPVB provided adequate analgesia in patients undergoing MRM; however, TPVB had better efficacy and opioid-sparing effect when compared to ESPB.
背景与目的:与胸椎旁阻滞(TPVB)相比,竖脊平面阻滞(ESPB)是一种新的区域麻醉技术,可以缓解乳房手术术后疼痛。改良根治性乳房切除术(MRM)是一种常用的乳腺癌手术。本研究的目的是比较ESPB和TPVB在MRM术后疼痛缓解方面的疗效。材料和方法:本研究是在某三级护理教学医院进行的前瞻性随机研究。60例ASA I-III成年患者(年龄18岁)计划接受选择性单侧磁共振成像治疗乳腺癌。术前采用0.25%布比卡因超声引导下ESPB或TPVB,随机分为ESPB组和TPVB组。所有患者均接受患者自控镇痛以缓解术后疼痛。分别于术后3、6、12、24 h记录吗啡用量及疼痛视觉模拟评分(VAS)。结果:首先,两组术后3、6、12、24 h VAS平均评分差异无统计学意义,不同时间点比较具有可比性。ESPB组24 h吗啡用量显著高于ESPB组(P = 0.035)。block表演的持续时间也有显著差异,ESPB的表演时间更短(P <0.001)。两组患者的平均年龄、体重指数(BMI)和住院时间相似。结论:ESPB和TPVB均可为MRM患者提供充分的镇痛;但与ESPB相比,TPVB具有更好的疗效和阿片节约作用。
{"title":"Comparison of fascial plane blocks (ESPB vs. TPVB) for pain relief following modified radical mastectomy","authors":"S Jayakrishnan, Amit Dua, Alok Kumar","doi":"10.4103/joacp.joacp_90_23","DOIUrl":"https://doi.org/10.4103/joacp.joacp_90_23","url":null,"abstract":"Abstract Background and Aims: The erector spinae plane block (ESPB) is a novel regional anesthesia technique compared to the thoracic paravertebral block (TPVB) in providing postoperative pain relief in breast surgeries. Modified radical mastectomy (MRM) is a commonly performed surgery for breast cancer. The objective of the study is to compare the efficacy of ESPB and TPVB in providing postoperative pain relief after MRM. Material and Methods: This is a prospective randomized study conducted in a tertiary care teaching hospital. Sixty ASA I–III adult patients (age >18 years) scheduled to undergo elective unilateral MRM for breast cancer were enrolled in the study. Ultrasound-guided ESPB or TPVB with 0.25% bupivacaine was performed preoperatively on the patients randomized into two groups, namely, the ESPB and TPVB groups. All patients received patient-controlled analgesia for postoperative pain relief. Morphine consumption and Visual Analog Score (VAS) for pain were recorded at 3, 6, 12, and 24 h postoperatively. Results: Primarily, the mean postoperative VAS scores between the two groups at 3, 6, 12, and 24 h showed no statistical significance and were comparable when matched at different time points. However, 24-h morphine consumption was significantly more in the ESPB group ( P = 0.035). Duration of block performance also showed a significant difference, with ESPB taking less time to perform ( P < 0.001). The mean age and body mass index (BMI) of patients and length of hospital stay in both the groups were similar. Conclusions: Both ESPB and TPVB provided adequate analgesia in patients undergoing MRM; however, TPVB had better efficacy and opioid-sparing effect when compared to ESPB.","PeriodicalId":14946,"journal":{"name":"Journal of Anaesthesiology, Clinical Pharmacology","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135483995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of Anaesthesiology, Clinical Pharmacology
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