Pub Date : 2019-12-30DOI: 10.13188/2575-7563.1000009
MicroRNAs (miRNAs) regulate the expression of genes involved in numerous cellular processes, including proliferation, metabolism, differentiation and apoptosis. Changes in the expression levels of miRNAs are associated with the development of various diseases, including cancer. Dysregulation of miRNA expression has been demonstrated to have a role in tumorigenesis and it has been revealed that some miRNAs can act either as oncogenes or tumor suppressors in cancer. miRNA-24 has been identified as an oncogene in various types of cancer. This review discusses the function of miRNA-24 as oncogene in gastric cancer, breast cancer, pancreatic cancer, lung cancer and leukemia.
{"title":"miR-24 and its Role as an Oncogene in Cancer","authors":"","doi":"10.13188/2575-7563.1000009","DOIUrl":"https://doi.org/10.13188/2575-7563.1000009","url":null,"abstract":"MicroRNAs (miRNAs) regulate the expression of genes involved in numerous cellular processes, including proliferation, metabolism, differentiation and apoptosis. Changes in the expression levels of miRNAs are associated with the development of various diseases, including cancer. Dysregulation of miRNA expression has been demonstrated to have a role in tumorigenesis and it has been revealed that some miRNAs can act either as oncogenes or tumor suppressors in cancer. miRNA-24 has been identified as an oncogene in various types of cancer. This review discusses the function of miRNA-24 as oncogene in gastric cancer, breast cancer, pancreatic cancer, lung cancer and leukemia.","PeriodicalId":149888,"journal":{"name":"Journal of Human Anatomy & Physiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126822149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-30DOI: 10.13188/2575-7563.1000010
Godwin E Shaibu
{"title":"Utilization of Prostate Serum Antigen (PSA) Screening Services among the Igala People of North Central Nigeria","authors":"Godwin E Shaibu","doi":"10.13188/2575-7563.1000010","DOIUrl":"https://doi.org/10.13188/2575-7563.1000010","url":null,"abstract":"","PeriodicalId":149888,"journal":{"name":"Journal of Human Anatomy & Physiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116080296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-30DOI: 10.13188/2575-7563.1000007
I. Yildiz, O. Kitis, A. Gonul
Objective: Magnetic Resonance Imaging (MRI) has very high soft tissue resolution that’s why we are able to discriminate gray matter and white matter y well voxel based volume analysis can reliably be made. In this study we aimed to investigate the volume differences of the total brain, gray matter, white matter and cerebrospinal fluid (CSF) between healthy controls and the subgroups of schizophrenia which are deficit syndrome (DS) and non-deficit syndrome (NDS).
{"title":"Gray Matter, White Matter and Cerebrospinal Volume in Schizophrenia and Subgroups: Mr Segmentation and Volumetric Study","authors":"I. Yildiz, O. Kitis, A. Gonul","doi":"10.13188/2575-7563.1000007","DOIUrl":"https://doi.org/10.13188/2575-7563.1000007","url":null,"abstract":"Objective: Magnetic Resonance Imaging (MRI) has very high soft tissue resolution that’s why we are able to discriminate gray matter and white matter y well voxel based volume analysis can reliably be made. In this study we aimed to investigate the volume differences of the total brain, gray matter, white matter and cerebrospinal fluid (CSF) between healthy controls and the subgroups of schizophrenia which are deficit syndrome (DS) and non-deficit syndrome (NDS).","PeriodicalId":149888,"journal":{"name":"Journal of Human Anatomy & Physiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133552529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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