Pub Date : 2021-02-24DOI: 10.15406/JCCR.2021.14.00500
J. Morales, Merces Assumpcao-Morales
specifically, cholesterol, cigarette smoking status, and systolic blood pressure. It is interesting to note that age adjusted cardiovascular death risk per 10,000 person years escalates at a near hyperbolic response in patients with multiple of these aforementioned risk factors after suffering with diabetes over 10years.6 Likewise, the converse may apply where intensive treatment with reduction of risk factors mentioned lit led to significant reduction in cumulative death and cardiovascular events as was demonstrated in the historic STENO 2 trial.7
{"title":"Diabetes, the kidney and the heart-A tale of metabolic mayhem","authors":"J. Morales, Merces Assumpcao-Morales","doi":"10.15406/JCCR.2021.14.00500","DOIUrl":"https://doi.org/10.15406/JCCR.2021.14.00500","url":null,"abstract":"specifically, cholesterol, cigarette smoking status, and systolic blood pressure. It is interesting to note that age adjusted cardiovascular death risk per 10,000 person years escalates at a near hyperbolic response in patients with multiple of these aforementioned risk factors after suffering with diabetes over 10years.6 Likewise, the converse may apply where intensive treatment with reduction of risk factors mentioned lit led to significant reduction in cumulative death and cardiovascular events as was demonstrated in the historic STENO 2 trial.7","PeriodicalId":15200,"journal":{"name":"Journal of Cardiology & Current Research","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78569337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-23DOI: 10.15406/JCCR.2021.14.00499
A. Franchina, S. D. Tomasello, S. Azzarelli, F. Scardaci, V. Argentino, F. Amico
{"title":"Staged rotational atherectomy in a patient with acute ST-elevation myocardial infarction: a case report","authors":"A. Franchina, S. D. Tomasello, S. Azzarelli, F. Scardaci, V. Argentino, F. Amico","doi":"10.15406/JCCR.2021.14.00499","DOIUrl":"https://doi.org/10.15406/JCCR.2021.14.00499","url":null,"abstract":"","PeriodicalId":15200,"journal":{"name":"Journal of Cardiology & Current Research","volume":"101 1","pages":"5-7"},"PeriodicalIF":0.0,"publicationDate":"2021-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85915424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.15406/JCCR.2021.14.00498
A. Silva
The correlations among the psychic repercussions of acute and chronic stress on the atherosclerotic process due to psychosomatic disorders were described more consistently since the middle of the 20th century. The revival of the attentions to them has been revitalized by the necessity to understand, diagnose and treat the effects of the Covid-19 pandemics in the cardiac patients. A pivotal exemplary work demonstrated the relationship of stress and atherosclerosis was experimentally compared when rabbits were placed on a lipid-rich diet in which atherosclerosis was developed (about 40%); however, if in addition to the diet, the animals were submitted to a continuous stress or the administration of benzedrine, about 90% of them presented generalized atheromas The increased risk of coronary heart disease in stress patients is well known. However, prisoners in concentration and war camps, under a strong state of stress, did not present the risk of coronary heart disease, but those who suffered an impact from a hurricane, earthquake or deprivation or even ignominy are deeply affected, bringing harm to the body. Attention must be payed to the importance of the peculiarities of each individually; responses to the stressful factor may depend on their genetic predisposition and specific unconscious fantasies, own and characteristics of each person. Unconscious conflicts would prepare their responses to stressful factors. Studies presented from different perspectives to link them the environmental stress as is presently the Covid-19 occurrence.
{"title":"The influence of type a personality in cardiovascular disease","authors":"A. Silva","doi":"10.15406/JCCR.2021.14.00498","DOIUrl":"https://doi.org/10.15406/JCCR.2021.14.00498","url":null,"abstract":"The correlations among the psychic repercussions of acute and chronic stress on the atherosclerotic process due to psychosomatic disorders were described more consistently since the middle of the 20th century. The revival of the attentions to them has been revitalized by the necessity to understand, diagnose and treat the effects of the Covid-19 pandemics in the cardiac patients. A pivotal exemplary work demonstrated the relationship of stress and atherosclerosis was experimentally compared when rabbits were placed on a lipid-rich diet in which atherosclerosis was developed (about 40%); however, if in addition to the diet, the animals were submitted to a continuous stress or the administration of benzedrine, about 90% of them presented generalized atheromas The increased risk of coronary heart disease in stress patients is well known. However, prisoners in concentration and war camps, under a strong state of stress, did not present the risk of coronary heart disease, but those who suffered an impact from a hurricane, earthquake or deprivation or even ignominy are deeply affected, bringing harm to the body. Attention must be payed to the importance of the peculiarities of each individually; responses to the stressful factor may depend on their genetic predisposition and specific unconscious fantasies, own and characteristics of each person. Unconscious conflicts would prepare their responses to stressful factors. Studies presented from different perspectives to link them the environmental stress as is presently the Covid-19 occurrence.","PeriodicalId":15200,"journal":{"name":"Journal of Cardiology & Current Research","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73509623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.15406/jccr.2021.14.00515
C. Kairis, Stavroula Kamtsiki, M. Tselegkidi, G. Trellopoulos, Achilleas Siozopoulos
A 56-year-old female patient came at the end of August to the office due to uncontrolled hypertension. Since she was a thin person without a family history of persistant hypertension, suspicion of secondary hypertension was induced and advised for biochemical end imaging tests. The final diagnosis was renovascular hypertension, the most common cause of secondary hypertension. Renal arteriography indicated a 99% stenosis to the left and the patient underwent a successful stent implantation. After angioplasty, blood pressure returned to normal and the patient did not receive medication. Invasive therapy is recommended for resistant hypertension (at least 4 antihypertensive drugs), aggravation of renal function and patients with flash pulmonary edema or congestive heart failure with preserved ejection fraction (EF).
{"title":"Renovascular disease: a common cause of secondary hypertension","authors":"C. Kairis, Stavroula Kamtsiki, M. Tselegkidi, G. Trellopoulos, Achilleas Siozopoulos","doi":"10.15406/jccr.2021.14.00515","DOIUrl":"https://doi.org/10.15406/jccr.2021.14.00515","url":null,"abstract":"A 56-year-old female patient came at the end of August to the office due to uncontrolled hypertension. Since she was a thin person without a family history of persistant hypertension, suspicion of secondary hypertension was induced and advised for biochemical end imaging tests. The final diagnosis was renovascular hypertension, the most common cause of secondary hypertension. Renal arteriography indicated a 99% stenosis to the left and the patient underwent a successful stent implantation. After angioplasty, blood pressure returned to normal and the patient did not receive medication. Invasive therapy is recommended for resistant hypertension (at least 4 antihypertensive drugs), aggravation of renal function and patients with flash pulmonary edema or congestive heart failure with preserved ejection fraction (EF).","PeriodicalId":15200,"journal":{"name":"Journal of Cardiology & Current Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89352382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.15406/jccr.2021.14.00510
G. Fazio, M. Campione
Aortic dissection is often reported in association with carotid or other vessel dissection. We report a case of 75-year old patient who underwent surgical treatment for aortic dissection in 2001. A routine carotid doppler shows bilateral carotid dissection even though the repaired aortic arch is normal.
{"title":"eral carotid dissection in a patient with a previous surgical treatment for aortic dissection","authors":"G. Fazio, M. Campione","doi":"10.15406/jccr.2021.14.00510","DOIUrl":"https://doi.org/10.15406/jccr.2021.14.00510","url":null,"abstract":"Aortic dissection is often reported in association with carotid or other vessel dissection. We report a case of 75-year old patient who underwent surgical treatment for aortic dissection in 2001. A routine carotid doppler shows bilateral carotid dissection even though the repaired aortic arch is normal.","PeriodicalId":15200,"journal":{"name":"Journal of Cardiology & Current Research","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78974706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.15406/jccr.2021.14.00524
D. Pomaro, Francisco A H Fonseca, A. Saldanha, V. Lanzoni, D. Casarini, A. Margeotto, André Lv, T. Bellincanta, Tania Leme da Rocha Martinez, Silvia SM Ihara
Purpose: The aim of this study was to evaluate the effect of angiotensin-converting enzyme (ACE) inhibitor on the liver histopathological changes in hypercholesterolemic and diabetic rabbits. Methods: New Zealand rabbits were treated by a single dose of alloxan (100mg iv) and were fed a chow with 0.5% cholesterol for 12weeks. The animals were divided into four groups according to the level of blood glucose: ≥250 mg/dL for groups I (n =10) and II (n=8) or <250mg/dL for groups III (n=12) and IV (n=12) and the groups II and IV were treated with an ACE inhibitor, quinapril (30mg/d) added to the diet. Total serum cholesterol and glucose levels and ACE activity were determined. Histological analysis was performed on liver samples stained with hematoxylin and eosin and picrosirius red. Liver fibrosis was analyzed by Metavir classification and was quantified by Image Tool software in picrosirius polarized images. Results: The four groups were hypercholesterolemic, without significant statistical differences in cholesterol levels among them. ACE activity was lower in the plasma of animals treated with ACE inhibitor (groups II and IV, p<0,01). We observed lower collagen area determined histomorphometrically in the both groups treated with ACE inhibitors, although only in the group with blood glucose control, there have been statistically significant. (p<0.05; group IV
{"title":"Diabetes and hypercholesterolemia experimental study on inhibition of liver fibrosis by angiotensin converting enzymes","authors":"D. Pomaro, Francisco A H Fonseca, A. Saldanha, V. Lanzoni, D. Casarini, A. Margeotto, André Lv, T. Bellincanta, Tania Leme da Rocha Martinez, Silvia SM Ihara","doi":"10.15406/jccr.2021.14.00524","DOIUrl":"https://doi.org/10.15406/jccr.2021.14.00524","url":null,"abstract":"Purpose: The aim of this study was to evaluate the effect of angiotensin-converting enzyme (ACE) inhibitor on the liver histopathological changes in hypercholesterolemic and diabetic rabbits. Methods: New Zealand rabbits were treated by a single dose of alloxan (100mg iv) and were fed a chow with 0.5% cholesterol for 12weeks. The animals were divided into four groups according to the level of blood glucose: ≥250 mg/dL for groups I (n =10) and II (n=8) or <250mg/dL for groups III (n=12) and IV (n=12) and the groups II and IV were treated with an ACE inhibitor, quinapril (30mg/d) added to the diet. Total serum cholesterol and glucose levels and ACE activity were determined. Histological analysis was performed on liver samples stained with hematoxylin and eosin and picrosirius red. Liver fibrosis was analyzed by Metavir classification and was quantified by Image Tool software in picrosirius polarized images. Results: The four groups were hypercholesterolemic, without significant statistical differences in cholesterol levels among them. ACE activity was lower in the plasma of animals treated with ACE inhibitor (groups II and IV, p<0,01). We observed lower collagen area determined histomorphometrically in the both groups treated with ACE inhibitors, although only in the group with blood glucose control, there have been statistically significant. (p<0.05; group IV<III). Conclusion: Our results suggest a benefit in liver protection achieved by the use of an ACE inhibitor in hypercholesterolemic and diabetic rabbits. This study highlights the importance of the renin-angiotensin system in protecting organs affected by high levels of lipids and glucose. to that observed after stimulation of these cells with endothelin 1, considered the most powerful contractile agent for this cell line. inhibition of the the of collagen type and expansion interstitial in different tissues. Some showed reduced messenger RNA levels of TGF-β 1 and procollagen I in the livers of rats treated with captopril after duct ligation common bile duct, supporting the hypothesis of an action of Ang II in cells hepatic stellate. 24,30","PeriodicalId":15200,"journal":{"name":"Journal of Cardiology & Current Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86749204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.15406/jccr.2021.14.00517
A. Leone
Carbon monoxide and nicotine are the main compounds able to cause cardiovascular damage. The first chemical is primarily responsible of irreversible cardiovascular damage in the time, whereas nicotine causes primarily a functional and reversible harm to the heart and blood vessels in both active smokers and individuals passively exposed to tobacco smoking. However, an irreversible damage is the final result of nicotine effects Evidence also indicates that carbon monoxide damages heavily respiratory system.
{"title":"Is cigarette smoking damaging more severely cardiovascular system in COVID-19 era?","authors":"A. Leone","doi":"10.15406/jccr.2021.14.00517","DOIUrl":"https://doi.org/10.15406/jccr.2021.14.00517","url":null,"abstract":"Carbon monoxide and nicotine are the main compounds able to cause cardiovascular damage. The first chemical is primarily responsible of irreversible cardiovascular damage in the time, whereas nicotine causes primarily a functional and reversible harm to the heart and blood vessels in both active smokers and individuals passively exposed to tobacco smoking. However, an irreversible damage is the final result of nicotine effects Evidence also indicates that carbon monoxide damages heavily respiratory system.","PeriodicalId":15200,"journal":{"name":"Journal of Cardiology & Current Research","volume":"656 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77683285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.15406/jccr.2021.14.00521
Djeinaba Kane, Soukaina Benbakh, I. Zallé, Mouhcine El Mardouli, Z. Zouizra, D. Boumzebra
Cardiovascular abnormalities are common in Turner syndrome. Coarctation of the aorta and aortic bicuspid valve are more commonly found. The presence of a subaortic membrane in patients with Turner syndrome has rarely been reported in the literature. We report a case of an isolated subaortic membrane responsible for severe sub valvular stenosis in a 26-year-old woman. The patient underwent surgical excision phase of the membrane under cardiopulmonary bypass. The post-operative course was uneventful.
{"title":"Subaortic membrane in a turner syndrome: A case report","authors":"Djeinaba Kane, Soukaina Benbakh, I. Zallé, Mouhcine El Mardouli, Z. Zouizra, D. Boumzebra","doi":"10.15406/jccr.2021.14.00521","DOIUrl":"https://doi.org/10.15406/jccr.2021.14.00521","url":null,"abstract":"Cardiovascular abnormalities are common in Turner syndrome. Coarctation of the aorta and aortic bicuspid valve are more commonly found. The presence of a subaortic membrane in patients with Turner syndrome has rarely been reported in the literature. We report a case of an isolated subaortic membrane responsible for severe sub valvular stenosis in a 26-year-old woman. The patient underwent surgical excision phase of the membrane under cardiopulmonary bypass. The post-operative course was uneventful.","PeriodicalId":15200,"journal":{"name":"Journal of Cardiology & Current Research","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77973374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.15406/jccr.2021.14.00536
G. Fazio
In 2014 it was estimated at 8.5% of the world population, compared to 4.7% in 1980. According to these estimates, there were about 422million people affected by diabetes mellitus in the world, 64million within the WHO European Region (Global report on diabetes, WHO 2016). In Italy, based on ISTAT data, in 2016 a prevalence of known diabetes was estimated to be 5.3% (5.4% in men, 5.2% in women) equal to over 3million people. The prevalence increases with increasing age to a value of about 20% in people aged 75years or older.
{"title":"The new antidiabetics in heart disease: can a glycemic holter predict the drug success?","authors":"G. Fazio","doi":"10.15406/jccr.2021.14.00536","DOIUrl":"https://doi.org/10.15406/jccr.2021.14.00536","url":null,"abstract":"In 2014 it was estimated at 8.5% of the world population, compared to 4.7% in 1980. According to these estimates, there were about 422million people affected by diabetes mellitus in the world, 64million within the WHO European Region (Global report on diabetes, WHO 2016). In Italy, based on ISTAT data, in 2016 a prevalence of known diabetes was estimated to be 5.3% (5.4% in men, 5.2% in women) equal to over 3million people. The prevalence increases with increasing age to a value of about 20% in people aged 75years or older.","PeriodicalId":15200,"journal":{"name":"Journal of Cardiology & Current Research","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73421780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.15406/jccr.2021.14.00520
S. Limaye
A 63-year-old man with a history of hypertension, hyperlipidemia, tobacco use, and hepatitis C status-post treatment presented to the Emergency Department with a two-hour history of sudden-onset stabbing central chest pain with radiation to the back. He experienced diaphoresis and nausea during the onset of chest pain. The patient was given aspirin and experienced some relief with the third tablet of nitroglycerin. Chest X-ray showed no acute findings. An ECG was performed (Figure 1) and showed upsloping ST-segment depression at the J point in the precordial leads with progression into tall, symmetric T waves in these leads and mild ST-segment elevation in lead aVR.
{"title":"A nuanced diagnosis with grave implications: importance of a rare ECG Pattern","authors":"S. Limaye","doi":"10.15406/jccr.2021.14.00520","DOIUrl":"https://doi.org/10.15406/jccr.2021.14.00520","url":null,"abstract":"A 63-year-old man with a history of hypertension, hyperlipidemia, tobacco use, and hepatitis C status-post treatment presented to the Emergency Department with a two-hour history of sudden-onset stabbing central chest pain with radiation to the back. He experienced diaphoresis and nausea during the onset of chest pain. The patient was given aspirin and experienced some relief with the third tablet of nitroglycerin. Chest X-ray showed no acute findings. An ECG was performed (Figure 1) and showed upsloping ST-segment depression at the J point in the precordial leads with progression into tall, symmetric T waves in these leads and mild ST-segment elevation in lead aVR.","PeriodicalId":15200,"journal":{"name":"Journal of Cardiology & Current Research","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79610765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：