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The Effects of Magnesium Sulfate with Lidocaine for Infraclavicular Brachial Plexus Block for Upper Extremity Surgeries. 硫酸镁联合利多卡因治疗上肢手术锁骨下臂丛神经阻滞的效果。
IF 0.7 Q4 CLINICAL NEUROLOGY Pub Date : 2020-11-06 eCollection Date: 2020-01-01 DOI: 10.1055/s-0040-1715578
Siavash Beiranvand, Arash Karimi, Majid Haghighat Shoar, Maryam Baghizadeh Baghdashti

Background  An addition of analgesic to anesthetic agents is likely to increase the effects of anesthesia and reduce associated adverse outcomes. Several adjuvants are studied in this regard. The aim of this study is to investigate the effects of adding a magnesium adjunct to lidocaine for the induction of infraclavicular block. Methods  Patients referred to Shohada Ashayer Hospital, Khorramabad, for wrist and hand surgery were enrolled in this study. The intervention/case group included patients who received 18 mL lidocaine (2%) + 2 mL magnesium sulfate (50%), 10 mL normal saline; control group: 18 mL lidocaine (2%) + 12 mL of normal saline. After the induction of ultrasound-guided infraclavicular block, parameters such as duration of reach with respect to complete sensory and motor block, hemodynamic parameters (hypotension and bradycardia), and postoperative pain, using visual analogue scale criteria, were measured. The obtained data were analyzed using a Bayesian path analysis model. Results  A total of 30 patients were included in each group. In the case group, sensory and motor block was achieved for 12.136 ± 4.96 and 13 ± 3.589 minutes more than those in the control group. The duration of sedation and immobilization was 2.57 ± 0.764 minute and 4.66 ± 0.909 minutes lengthier in the case group. Regarding the hemodynamic parameters, blood pressure was 0.217 ± 5.031 and 1.59 ± 5.14 units lower in the case group, immediately following the block and the surgery. Similarly, heart rate was 0.776 ± 4.548 and 0.39 ± 3.987 units higher in the case group, after 30 minutes and 2 hours of the procedure. A decrease in the pain was seen at 8, 10, and 12 hours after the surgery, as compared with the control group. An addition of magnesium to lidocaine for infraclavicular block resulted in a significantly longer sedation and immobilization period and decreased postoperative pain at 12 hours. Conclusion  Heart rate and blood pressure did not decrease significantly in the case group. It can be concluded that addition of magnesium sulfate to lidocaine can produce better anesthetic and analgesic outcomes with low-to-no adverse effects.

背景:在麻醉药物中加入镇痛药可能会增加麻醉效果,减少相关不良后果。在这方面研究了几种佐剂。本研究的目的是探讨在利多卡因中加入镁佐剂诱导锁骨下阻滞的效果。方法选取在霍拉马巴德Shohada Ashayer医院行腕部和手部手术的患者。干预/病例组包括:接受利多卡因18 mL(2%) +硫酸镁2 mL(50%),生理盐水10 mL;对照组:利多卡因18 mL(2%) +生理盐水12 mL。超声引导锁骨下阻滞诱导后,采用视觉模拟评分标准测量感觉和运动完全阻滞的到达时间、血流动力学参数(低血压和心动过缓)和术后疼痛等参数。使用贝叶斯路径分析模型对获得的数据进行分析。结果每组共纳入30例患者。病例组感觉和运动阻滞时间分别比对照组长12.136±4.96和13±3.589分钟。病例组镇静和固定时间分别延长2.57±0.764分钟和4.66±0.909分钟。在血流动力学参数方面,病例组在阻滞和手术后血压分别降低0.217±5.031和1.59±5.14个单位。同样,在手术30分钟和2小时后,病例组的心率分别提高了0.776±4.548和0.39±3.987单位。与对照组相比,术后8小时、10小时和12小时疼痛有所减轻。在利多卡因基础上添加镁治疗锁骨下阻滞,镇静和固定时间明显延长,术后12小时疼痛减轻。结论病例组心率、血压无明显下降。由此可见,在利多卡因中加入硫酸镁可获得较好的麻醉镇痛效果,且不良反应低至无。
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引用次数: 9
Pain Relief after Surgical Decompression of the Distal Brachial Plexus. 臂丛远端减压术后疼痛的缓解。
IF 0.7 Q4 CLINICAL NEUROLOGY Pub Date : 2020-10-16 eCollection Date: 2020-01-01 DOI: 10.1055/s-0040-1716718
Richard Morgan, Iain Elliot, Vibhu Banala, Christopher Dy, Briana Harris, Elizabeth Anne Ouellette

Background  Brachial plexopathy causes pain and loss of function in the affected extremity. Entrapment of the brachial plexus terminal branches within the surrounding connective tissue, or medial brachial fascial compartment, may manifest in debilitating symptoms. Open fasciotomy and external neurolysis of the neurovascular bundle in the medial brachial fascial compartment were performed as a surgical treatment for pain and functional decline in the upper extremity. The aim of this study was to evaluate pain outcomes after surgery in patients diagnosed with brachial plexopathy. Methods  We identified 21 patients who met inclusion criteria. Documents dated between 2005 and 2019 were reviewed from electronic medical records. Chart review was conducted to collect data on visual analog scale (VAS) for pain, Semmes-Weinstein monofilament test (SWMT), and Medical Research Council (MRC) scale for muscle strength. Pre- and postoperative data was obtained. A paired sample t -test was used to determine statistical significance of pain outcomes. Results  Pain severity in the affected arm was significantly reduced after surgery (pre: 6.4 ± 2.5; post: 2.0 ± 2.5; p  < 0.01). Additionally, there was an increased response to SWMT after the procedure. More patients achieved an MRC rating score ≥3 and ≥4 in elbow flexion after surgery. This may be indicative of improved sensory and motor function. Conclusion  Open fasciotomy and external neurolysis at the medial brachial fascial compartment is an effective treatment for pain when nerve continuity is preserved. These benefits were evident in patients with a prolonged duration elapsed since injury onset.

臂丛病在患肢引起疼痛和功能丧失。臂丛末端分支在周围结缔组织或内侧臂丛筋膜间室内的卡压可表现为衰弱症状。开放性筋膜切开术和肱内侧筋膜室神经血管束外松解术是上肢疼痛和功能下降的手术治疗方法。本研究的目的是评估诊断为臂丛病的患者手术后的疼痛结局。方法选取21例符合入选标准的患者。从电子医疗记录中查看了2005年至2019年之间的文件。通过图表回顾收集疼痛的视觉模拟量表(VAS)、Semmes-Weinstein单丝测试(SWMT)和肌肉力量的医学研究委员会(MRC)量表的数据。获得术前和术后数据。采用配对样本t检验确定疼痛结局的统计学意义。结果术后患臂疼痛严重程度明显减轻(术前:6.4±2.5;Post: 2.0±2.5;结论在保持神经连续性的前提下,开放性筋膜切开联合肱内侧筋膜室外松解术是治疗疼痛的有效方法。这些益处在损伤发作后持续时间较长的患者中表现明显。
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引用次数: 2
An Additional Electrodiagnostic Tool for Ulnar Neuropathy: Mixed across the Elbow. 尺神经病变的另一种电诊断工具:混合在肘部。
IF 0.7 Q4 CLINICAL NEUROLOGY Pub Date : 2020-08-26 eCollection Date: 2020-01-01 DOI: 10.1055/s-0040-1714742
Drew B Parkhurst, Michael T Andary, John W Powell

Background  Diagnosing ulnar neuropathy at the elbow (UNE) remains challenging despite guidelines from national organizations. Motor testing of hand intrinsic muscles remains a common diagnostic method fraught with challenges. Objective  The aim of the study is to demonstrate utility of an uncommon nerve conduction study (NCS), mixed across the elbow, when diagnosing UNE. Methods  Retrospective analysis of 135 patients, referred to an outpatient University-based electrodiagnostic laboratory with suspected UNE between January 2013 and June 2019 who had motor to abductor digiti minimi (ADM), motor to first dorsal interosseus (FDI), and mixed across the elbow NCS completed. To perform the mixed across the elbow NCS, the active bar electrode was placed 10-cm proximal to the medial epicondyle between the biceps and triceps muscle bellies. The median nerve was stimulated at the wrist followed by stimulation of the ulnar nerve at the ulnar styloid. The difference between peak latencies, labeled the ulnar-median mixed latency difference (U-MLD), was used to evaluate for correlation between the nerve conduction velocities (NCV) of ADM and FDI. Results  Pearson r -values = -0.479 and -0.543 ( p  < 0.00001) when comparing U-MLD to ADM and FDI NCV across the elbow, respectively. The negative r -value describes the inverse relationship between ulnar velocity across the elbow and increasing U-MLD. Conclusion  Mixed across the elbow has moderate-strong correlation with ADM and FDI NCV across the elbow. All three tests measure ulnar nerve function slightly differently. Without further prospective data, the most accurate test remains unclear. The authors propose some combination of the three tests may be most beneficial when diagnosing UNE.

背景:尽管国家组织制定了指导方针,但肘部尺神经病变(UNE)的诊断仍然具有挑战性。手部固有肌肉的运动测试仍然是一种常见的诊断方法,充满了挑战。目的:本研究的目的是展示罕见神经传导检查(NCS)在诊断UNE时的实用性,该检查在肘部混合。方法回顾性分析2013年1月至2019年6月在大学门诊电诊断实验室就诊的135例疑似UNE患者,这些患者有运动到小指外展肌(ADM),运动到第一背骨间肌(FDI),并完成了混合肘关节NCS。在肱二头肌和肱三头肌腹部之间的内侧上髁近端10 cm处放置活动杆电极,以进行混合肘关节NCS。在手腕处刺激正中神经然后在尺茎突处刺激尺神经。峰值潜伏期之差称为尺正中混合潜伏期差(U-MLD),用于评价ADM与FDI的神经传导速度(NCV)之间的相关性。Pearson r值= -0.479和-0.543 (p r值)描述了肘部尺速度与U-MLD增加之间的反比关系。结论混合肘关节与横过肘关节的ADM和FDI NCV有中强相关性。这三种测试对尺神经功能的测量略有不同。没有进一步的前瞻性数据,最准确的测试仍然不清楚。作者提出,在诊断UNE时,三种检查的某种组合可能是最有益的。
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引用次数: 1
7 From Cold War Pressures to State Policy to People’s Health: Social Medicine and Socialized Medical Care in Chile 从冷战压力到国家政策再到人民健康:智利的社会医学和社会化医疗
IF 0.7 Q4 CLINICAL NEUROLOGY Pub Date : 2020-07-24 DOI: 10.1515/9781478012221-010
Jadwiga E. Pieper Mooney
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引用次数: 1
“Psychotherapy of the Oppressed”: “被压迫者的心理治疗”:
IF 0.7 Q4 CLINICAL NEUROLOGY Pub Date : 2020-07-24 DOI: 10.2307/j.ctv14t48qj.13
Marco Ramos
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引用次数: 0
ACKNOWLEDGMENTS 致谢
IF 0.7 Q4 CLINICAL NEUROLOGY Pub Date : 2020-07-24 DOI: 10.1515/9781478012221-002
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引用次数: 0
INDEX 指数
IF 0.7 Q4 CLINICAL NEUROLOGY Pub Date : 2020-07-24 DOI: 10.2307/j.ctv14t48qj.18
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引用次数: 0
EPILOGUE. A Lingering Cold (War)? Reflections for the Present and an Agenda for Further Research 后记。持续的冷战?当前的思考和进一步研究的议程
IF 0.7 Q4 CLINICAL NEUROLOGY Pub Date : 2020-07-24 DOI: 10.1515/9781478012221-013
A. Birn, Raúl Necochea López
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引用次数: 0
Parasitology and Communism: 寄生虫学与共产主义:
IF 0.7 Q4 CLINICAL NEUROLOGY Pub Date : 2020-07-24 DOI: 10.2307/j.ctv14t48qj.10
Gilberto Hochman, C. Paiva
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引用次数: 0
National Politics and Scientific Pursuits: 国家政治与科学追求:
IF 0.7 Q4 CLINICAL NEUROLOGY Pub Date : 2020-07-24 DOI: 10.2307/j.ctv14t48qj.7
Nicole L. Pacino
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Journal of Brachial Plexus and Peripheral Nerve Injury
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