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Prevalence of Chronic Liver Disease Based on Ultrasound Shear Wave Elastography in an Adult Asian Indian Population Attending Outpatient Preventive Radiology Clinics in India. 基于超声剪切波弹性成像的印度亚裔成人慢性肝病患病率
IF 1.2 4区 医学 Q3 ACOUSTICS Pub Date : 2024-11-08 DOI: 10.1002/jcu.23888
Rijo M Choorakuttil, Rajas N Chaubal, Thara Pratap, Venkatesh K Arunachalam, S Harish Kumar, Neha Bagri, Anjali Gupta, Amarnath Chelladurai, Praveen K Nirmalan

Aim: To determine the ultrasound shear wave elastography (SWE)-based prevalence of chronic liver disease in an adult Asian Indian population attending preventive radiology outpatient clinics in India.

Methods: Liver stiffness measures (LSMs) were ascertained using ultrasound SWE and interquartile range/median (IQR/M) ratio ≤ 30% kilopascal (kPa) units were considered a good quality measurement. Details of modifiable risk factors including comorbidity and personal risk behaviors were collected. The liver was graded based on the Society of Radiologists in Ultrasound Liver Elastography Consensus Statement and Grades 4 and 5 indicated compensated advanced chronic liver disease (cACLD) and clinically significant portal hypertension (CSPH). A multivariate logistic regression model was used to analyze associations with chronic advanced liver disease.

Results: The median LSM in the study participants (n = 1145) was 8.0 (IQR 6.5, 9.85) kPa units. 10.65% of the study population had advanced chronic liver disease (cACLD and CSPH) and 22.79% had LSM that was suggestive of cACLD. cACLD and CSPH were significantly associated with comorbidities, personal risk behaviors, and lean and obese body mass indices. Modifiable risk factors were present in 20%-50% of participants with LSM between 7 and 13 kPa.

Conclusion: Information on the prevalence of LSM-based cACLD and CSPH and modifiable risk factors in persons with LSM between 7 and 13 kPa will help to design preventative strategies using LSM as an objective imaging biomarker.

目的:确定在印度预防放射学门诊就诊的亚裔印度成年人群中基于超声剪切波弹性成像(SWE)的慢性肝病患病率:方法: 使用超声波剪切波弹性成像技术确定肝脏僵硬度(LSM),四分位数范围/中位数(IQR/M)比值≤30%千帕(kPa)单位被认为是高质量的测量结果。收集了可改变风险因素的详细信息,包括合并症和个人风险行为。根据放射学会肝脏弹性成像共识声明对肝脏进行分级,4 级和 5 级表示代偿性晚期慢性肝病(cACLD)和临床显著门脉高压症(CSPH)。采用多变量逻辑回归模型分析与慢性晚期肝病的关系:研究参与者(n = 1145)的 LSM 中位数为 8.0(IQR 6.5,9.85)kPa 单位。10.65%的研究对象患有晚期慢性肝病(cACLD 和 CSPH),22.79%的研究对象的 LSM 提示患有 cACLD。20%-50%的 LSM 在 7-13 kPa 之间的参与者存在可改变的风险因素:有关基于 LSM 的 cACLD 和 CSPH 的患病率以及 LSM 在 7 到 13 kPa 之间的人的可改变的风险因素的信息将有助于设计使用 LSM 作为客观成像生物标志物的预防策略。
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引用次数: 0
Ultrasonic Image Characteristics of Palatine Tonsils in Healthy Children and Analysis of Factors Influencing Image Quality. 健康儿童腭扁桃体的超声波图像特征及影响图像质量的因素分析
IF 1.2 4区 医学 Q3 ACOUSTICS Pub Date : 2024-11-05 DOI: 10.1002/jcu.23882
Ying Cao, Lei Sun, XiaoPeng Li, Qi Zhang, Yue Gao, Hua Wang

Objective: To explore the ultrasonic image characteristics of palatine tonsils in healthy children and the factors affecting image quality.

Methods: A total of 750 images of palatine tonsils were collected from 375 healthy children. According to ultrasonic image quality, the images were divided into three groups. Both systemic and local factors were analyzed among the different groups.

Results: The palatine tonsils showed quasi-circular or flat oval, low echo or light and dark band arrangement, a striped medium echo, and a clear boundary. Age, height, weight, body mass index, body surface area, distance from the skin to the posterior margin of the tonsils, thickness of the anterior soft tissue of the tonsils, and thickness of the anterior submandibular gland of the tonsils were significantly different among the different image quality groups (p < 0.05). Multivariate logistic regression analyses revealed that height, weight, thickness of the anterior soft tissue of the tonsils, and thickness of the anterior submandibular gland of the tonsils were independent factors affecting the quality of the ultrasonic images of the palatine tonsils.

Conclusions: There are characteristic ultrasonic image manifestations of the palatine tonsils. Tonsil ultrasound image quality is affected by individual and local factors.

目的:探讨健康儿童腭扁桃体的超声波图像特征及影响图像质量的因素:探讨健康儿童腭扁桃体的超声图像特征以及影响图像质量的因素:方法:共收集了 375 名健康儿童的 750 张腭扁桃体图像。根据超声图像质量将图像分为三组。结果:腭扁桃体的超声图像质量较差:腭扁桃体呈类圆形或扁椭圆形,低回声或明暗带排列,中回声呈条状,边界清晰。不同图像质量组的年龄、身高、体重、体质指数、体表面积、皮肤至扁桃体后缘的距离、扁桃体前软组织的厚度、扁桃体前颌下腺的厚度均有显著差异(P 结论:腭扁桃体的超声图像具有特征性表现,但不同图像质量组的差异较大:腭扁桃体有特征性的超声图像表现。扁桃体超声图像质量受个体和局部因素的影响。
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引用次数: 0
A Case With Gallbladder Villous Tubular Adenoma With High-Grade Intraepithelial Neoplasia Combined With Rectal Villous Tubular Adenocarcinoma. 一例胆囊绒毛管状腺瘤伴高级别上皮内瘤变合并直肠绒毛管状腺癌的病例
IF 1.2 4区 医学 Q3 ACOUSTICS Pub Date : 2024-11-04 DOI: 10.1002/jcu.23890
Muhammad Asad Iqbal, Hui Zhou, Ziou Zhao, Nida Fatima Moazzam, Jie Hou, Hui Sun, Xian Wang

We present the rare case of a 79-year-old female patient with the coexistence of gallbladder villous tubular adenoma and rectal villous tubular adenocarcinoma. She initially presented with blood in the stool, prompting a diagnosis of rectal cancer. Further examination revealed findings suggestive of a gallbladder pathology. Subsequent imaging and histopathological analyses confirmed the presence of a gallbladder villous tubular adenoma, high-grade intraepithelial neoplasia, and rectal villous tubular adenocarcinoma. Surgical interventions included laparoscopic radical resection of the rectal cancer and cholecystectomy. Immunohistochemical examination differentiated between the two distinct adenomatous conditions. This case underscores the importance of thorough evaluation and multidisciplinary approaches for accurate diagnosis and management of complex presentations of gastrointestinal neoplasms.

我们报告了一例罕见的病例,患者是一名 79 岁的女性,同时患有胆囊绒毛管状腺瘤和直肠绒毛管状腺癌。她最初出现便血症状,因此被诊断为直肠癌。进一步检查发现,她的病理结果提示胆囊病变。随后的影像学和组织病理学分析证实了胆囊绒毛管状腺瘤、高级别上皮内瘤变和直肠绒毛管状腺癌的存在。手术治疗包括腹腔镜直肠癌根治术和胆囊切除术。免疫组化检查区分了两种不同的腺瘤病症。本病例强调了全面评估和多学科方法对于准确诊断和处理复杂表现的胃肠道肿瘤的重要性。
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引用次数: 0
Study of Risk Factors and Image Findings of Isolated Abdominal Incidentally Detected Aortic Dissection. 孤立性腹部意外发现主动脉夹层的风险因素和图像结果研究
IF 1.2 4区 医学 Q3 ACOUSTICS Pub Date : 2024-11-04 DOI: 10.1002/jcu.23889
Hiromasa Tsubouchi, Hidenori Onishi, Koji Maeno, Masaya Nakagaichi, Ikue Tsukushi, Youichi Kitano, Yoshitaka Makino, Hiroyuki Hayashi, Hidekazu Terasawa, Hiroko Kabuto, Toshihiro Misawa, Taku Sanada, Azusa Hisada, Kazuo Notsumata, Kazuhiro Okafuji, Osamu Yamamura

Introduction: Isolated abdominal aortic dissection (IAAD) has been reported to account for 1.1%-4.1% of all aortic dissections. If detected late, it is associated with a risk of aortic rupture. We investigated the risk factors and characteristic imaging findings of incidentally discovered IAAD using abdominal ultrasonography (AUS) during health check-up and hereby report our findings.

Methods: The study sample included 41 patients with abdominal aortic abnormalities identified by AUS performed during a health check-up at our hospital and who were diagnosed with IAAD by contrast-enhanced computed tomography (CT); in addition, 205 patients were included in the nonevent group. Furthermore, risk factors and characteristic imaging findings of IAAD were examined retrospectively.

Results: Compared with the nonevent group, smoking and fatty liver were observed significantly more frequently in the IAAD group. Ultrasound findings indicated an intimal flap in 35 cases (85.4%), whereas CT scan revealed displacement of intimal calcifications in 32 cases (78.0%).

Conclusion: Compared with the nonevent group, there were significantly more cases of fatty liver and smoking habits in the IAAD group. In older patients with risk factors for fatty liver and smoking habits, if IAAD is suspected, it is important to monitor the abdominal aorta using ultrasonography during health check-ups.

导言:据报道,孤立性腹主动脉夹层(IAAD)占所有主动脉夹层的 1.1%-4.1%。如果发现较晚,则有主动脉破裂的风险。我们利用腹部超声波检查(AUS)对健康体检中偶然发现的主动脉夹层(IAAD)的风险因素和特征性成像结果进行了调查,并在此报告我们的研究结果:研究样本包括 41 名在我院健康体检中通过 AUS 发现腹主动脉异常,并通过对比增强计算机断层扫描(CT)确诊为 IAAD 的患者;此外,还包括 205 名非事件组患者。此外,还对 IAAD 的危险因素和特征性影像学结果进行了回顾性研究:结果:与非事件组相比,IAAD 组中吸烟和脂肪肝的发病率明显更高。超声检查结果显示有内膜瓣的有35例(85.4%),而CT扫描显示有内膜钙化移位的有32例(78.0%):结论:与非事件组相比,IAAD组中有脂肪肝和吸烟习惯的病例明显增多。对于有脂肪肝和吸烟习惯等危险因素的老年患者,如果怀疑有 IAAD,在体检时使用超声波检查监测腹主动脉非常重要。
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引用次数: 0
Ludenbach Syndrome: The Feasibility of Prenatal Ultrasound Diagnosis. 鲁登巴赫综合征:产前超声诊断的可行性。
IF 1.2 4区 医学 Q3 ACOUSTICS Pub Date : 2024-10-31 DOI: 10.1002/jcu.23887
Tian-Gang Li, Hai-Bo Cao, Bin Ma, Bo-Xi Li, Li-Guo Yao

Lutembacher syndrome has been reported primarily in children and adults, but no prenatal cases have been reported. Our results indicated that lutembacher syndrome could be diagnosed by using prenatal ultrasound diagnosis. Accurate prenatal diagnosis of lutembacher syndrome is beneficial to neonatal prognosis and treatment options; it is very necessary to make a clear diagnosis in utero.

据报道,卢滕巴赫综合征主要发生在儿童和成人身上,但还没有产前病例的报道。我们的研究结果表明,鲁坦巴赫综合征可以通过产前超声诊断确诊。准确的产前诊断有利于新生儿的预后和治疗方案的选择;在子宫内做出明确诊断是非常必要的。
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引用次数: 0
Abdominal POCUS Education for Clinicians: A Systematic Review of Teaching Methods for Point-of-Care Abdominal Ultrasonography. 临床医师的腹部 POCUS 教育:医疗点腹部超声造影教学方法的系统回顾。
IF 1.2 4区 医学 Q3 ACOUSTICS Pub Date : 2024-10-30 DOI: 10.1002/jcu.23876
Birkir Örn Sveinsson, Olof Kristin Thorsteinsdottir, Alexander G P Browne, Benjamin S B Rasmussen, Anders Bo Nielsen, Pia Iben Pietersen

This systematic review examines educational strategies in clinician-performed abdominal point-of-care ultrasound (POCUS), a critical skill with increasing relevance in medical care. Analyzing 28 studies, we highlight the strategies as well as advantages and disadvantages of various theoretical and practical components, including, for example, e-learning and simulation in training programs. The findings emphasize the necessity of blending various educational methods to enhance effectiveness and adaptability in training environments. Ultimately, robust training frameworks are essential to maximize diagnostic accuracy and improve patient outcomes in abdominal POCUS.

腹部护理点超声检查(POCUS)是一项在医疗护理中日益重要的关键技能,本系统性综述研究了临床医师操作腹部护理点超声检查的教育策略。通过对 28 项研究的分析,我们强调了各种理论和实践内容的策略和优缺点,例如培训项目中的电子学习和模拟。研究结果强调了融合各种教育方法的必要性,以提高培训环境的有效性和适应性。最终,强大的培训框架对于最大限度地提高腹部 POCUS 诊断准确性和改善患者预后至关重要。
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引用次数: 0
Antenatal Detection of a True Umbilical Cord Knot: Facilitating Optimal Delivery Management. 产前检测脐带真结:促进最佳分娩管理。
IF 1.2 4区 医学 Q3 ACOUSTICS Pub Date : 2024-10-29 DOI: 10.1002/jcu.23873
Shin Hashiramoto, Hiroko Takita, Tatsuya Arakaki, Yuka Yamashita, Mayumi Kaneko, Ryu Matsuoka, Akihiko Sekizawa

Prenatal diagnosis of a true umbilical cord knot is challenging. However, prenatal diagnosis is clinically valuable because it allows preparation for fetal distress during labor. Here, we report a case of prenatal diagnosis of true umbilical cord knot, with a favorable delivery management.

真性脐带打结的产前诊断具有挑战性。然而,产前诊断具有临床价值,因为它能为分娩时胎儿窘迫做好准备。在此,我们报告了一例产前诊断为真性脐带打结并顺利分娩的病例。
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引用次数: 0
Visual Patterns of Diaphragmatic Motion in Acute Respiratory Failure: A Prospective Pilot Study. 急性呼吸衰竭患者膈肌运动的视觉模式:前瞻性试点研究
IF 1.2 4区 医学 Q3 ACOUSTICS Pub Date : 2024-10-29 DOI: 10.1002/jcu.23886
Thibaut Markarian, Matthieu Daniel, Kevin Guillemet, Florian Ajavon, Florent Femy, Romain Genre Grandpierre, Anne-Laure Feral-Pierssens, Xavier Bobbia

Introduction: Right diaphragmatic excursion is a reliable and reproducible technique used in intensive care to assess diaphragmatic function. The aim of this study was to investigate the relationship between the appearance of diaphragmatic motion and the etiological diagnosis of patients admitted to the emergency department with acute respiratory failure (ARF).

Materials: A prospective, observational, and multicenter pilot study was conducted. All adult patients admitted in the emergency department with ARF were included. The different visual patterns of diaphragmatic motion were analyzed according to the three main etiologies of ARF encountered in emergency departments.

Results: A total of 39 adult patients were included. We observed a different visual pattern in patients with pneumonia. A sum of plateau times of less than 0.2 s predicted that the main diagnosis was pneumonia, with sensitivity = 89% 95%CI [52%; 100%], specificity = 87% 95%CI [69%; 96%].

Conclusion: Our study seems to show that the shape of diaphragmatic motion in patients with ARF secondary to pneumonia is different from that in patients with exacerbation of chronic obstructive pulmonary disease or acute heart failure.

Trial registration: ClinicalTrials.gov: NCT04591509.

介绍:右侧膈肌游离是重症监护中用于评估膈肌功能的一种可靠且可重复的技术。本研究旨在调查急性呼吸衰竭(ARF)急诊科入院患者的膈肌运动外观与病因诊断之间的关系:材料:开展了一项前瞻性、观察性、多中心试验研究。研究对象包括急诊科收治的所有急性呼吸衰竭成人患者。根据急诊科遇到的 ARF 的三种主要病因,分析膈肌运动的不同视觉模式:结果:共纳入 39 名成年患者。我们在肺炎患者中观察到了不同的视觉模式。高原时间总和小于 0.2 秒可预测主要诊断为肺炎,灵敏度 = 89% 95%CI [52%; 100%],特异性 = 87% 95%CI [69%; 96%]:我们的研究似乎表明,继发于肺炎的 ARF 患者的膈肌运动形状与慢性阻塞性肺病或急性心力衰竭加重期患者的膈肌运动形状不同:试验注册:ClinicalTrials.gov:试验注册:ClinicalTrials.gov:NCT04591509。
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引用次数: 0
Isolated Fetal Liver Calcifications: Case Report and Literature Review 孤立胎儿肝钙化:病例报告与文献综述
IF 1.2 4区 医学 Q3 ACOUSTICS Pub Date : 2024-10-28 DOI: 10.1002/jcu.23884
Martina Derme, Adele Vasta, Maria Caterina Corigliano, Antonio Arnò, Valentina D'Ambrosio, Daniele Di Mascio, Giuseppe Rizzo, Antonella Giancotti

Fetal liver calcifications (FLCs) are isolated or multiple areas of increased echogenicity in the fetal liver, with an estimated prevalence of 5–10 per 10 000 births. However, their clinical importance remains still unclear. Although they are often linked to infections, chromosomal disorders, thrombotic events, or tumors, isolated FLCs generally have a favorable outcome. This article aims to present a case of a 29-year-old pregnant woman with a low-risk cfDNA test, who presented for the first trimester screening scan at our hospital at 12 weeks of pregnancy. The morphology scan at 20 weeks and 5 days revealed a normal fetal size with areas of increased echogenicity in the liver. No other fetal issues were identified. The patient was monitored throughout her pregnancy at our center, receiving genetic counseling and tests for detecting cystic fibrosis, STORCH (syphilis, cytomegalovirus, herpes virus 1;2, rubella, and toxoplasma), fetal echocardiography, and MRI, all of which were normal. At 35 weeks and 6 days, the patient gave birth to a healthy male, and all subsequent postnatal examinations confirmed the baby's health. This article aims to offer comprehensive insights into the management and postnatal outcomes of isolated FLCs, based on a review of the literature.

胎儿肝钙化(FLCs)是胎儿肝脏中孤立或多发的回声增强区域,估计发生率为每万名新生儿中 5-10 例。然而,它们的临床重要性仍不明确。虽然它们通常与感染、染色体疾病、血栓事件或肿瘤有关,但孤立的FLCs一般都有良好的预后。本文旨在介绍一例 29 岁的低风险 cfDNA 检测孕妇,她在怀孕 12 周时来我院进行头三个月筛查扫描。20 周零 5 天时的形态学扫描显示胎儿大小正常,肝脏回声增强。没有发现其他胎儿问题。患者在本中心接受了整个孕期的监测,接受了遗传咨询、囊性纤维化检测、STORCH(梅毒、巨细胞病毒、疱疹病毒1;2、风疹和弓形虫)、胎儿超声心动图和核磁共振成像检查,所有检查结果均正常。患者在 35 周零 6 天时产下一名健康男婴,随后的所有产后检查均证实婴儿健康。本文旨在通过对文献的综述,对孤立性FLC的管理和产后结局提供全面的见解。
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引用次数: 0
Klippel-Trénaunay-Weber Syndrome: Prenatal Diagnosis and Review of the Literature. Klippel-Trénaunay-Weber 综合征:产前诊断和文献综述。
IF 1.2 4区 医学 Q3 ACOUSTICS Pub Date : 2024-10-28 DOI: 10.1002/jcu.23864
Orlandi Giuliana, Sarno Laura, Angelino Antonio, Motta Mariarosaria, Di Girolamo Raffaella, Carbone Luigi, Rovetto Marika, Mazzarelli Laura Letizia, Sglavo Gabriella, D' Antonio Francesco, Mappa Ilenia, Di Mascio Daniele, Rizzo Giuseppe, Maruotti Giuseppe Maria

Klippel-Trénaunay-Weber syndrome (KTW) is a rare congenital disease, representing a challenge in prenatal diagnosis due to overlapping characteristics with other syndromes and no specific genetic markers known to date. We have collected all the cases present in the literature on the prenatal diagnosis of KTW, emphasizing common ultrasound findings that can guide the clinician and genetics to the prenatal counseling. Thus, we collected all the information about the postnatal prognosis and the necessity for treatment. Our review of 44 cases highlights the typical common features: hemihypertrophy, predominantly affecting the right leg, with cystic lesions extending to the trunk or upper limbs and rare internal organ involvement. Prenatal complications, including hydrops and polyhydramnios, emphasize the need for a careful ultrasound follow-up. Despite no identified genetic mutation, genetic counseling and invasive testing are recommended. Mortality rate due to a severe complication known as Kasabach-Merritt syndrome, underlines the importance of early diagnosis and accurate management strategies. Prenatal diagnosis of KTW, guided by ultrasound findings and genetic counseling, could help with informed decision-making and optimal care planning.

Klippel-Trénaunay-Weber 综合征(KTW)是一种罕见的先天性疾病,由于其特征与其他综合征重叠,且迄今尚无特异性遗传标记物,因此是产前诊断的难题。我们收集了文献中所有关于 KTW 产前诊断的病例,强调了常见的超声波检查结果,这些结果可以为临床医生和遗传学产前咨询提供指导。因此,我们收集了有关产后预后和治疗必要性的所有信息。我们对 44 例病例的回顾突出了典型的共同特征:半肥大,主要累及右腿,囊性病变延伸至躯干或上肢,罕见的内脏器官受累。产前并发症包括肾积水和多胎畸形,因此需要进行仔细的超声随访。尽管没有发现基因突变,但建议进行遗传咨询和侵入性检测。卡萨巴赫-梅里特综合征(Kasabach-Merritt Syndrome)是一种严重的并发症,死亡率很高,这凸显了早期诊断和准确管理策略的重要性。在超声波检查结果和遗传咨询的指导下进行 KTW 产前诊断,有助于做出知情决策和制定最佳护理计划。
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引用次数: 0
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Journal of Clinical Ultrasound
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