Pub Date : 2017-06-20DOI: 10.4172/2155-9880.1000529
P. Köln, F. Kleber
The treatment of chronic total occlusions is complex and associated with several risks and problems. Among therapeutic options including bypass surgery and medical therapy PCI represents an important strategy. PCI with stents, however, has limitations in such lesions due to characteristics like lesion length, unknown reference diameter and delayed stent coverage. Drug coated balloons have shown promising properties to overcome some of those limitations: They promote positive vessel remodeling and have a minimal thrombosis rate. In a first multicenter study it has been shown that drug coated balloons in proper indications and applied with appropriate technique might become a new treatment option for patients with chronic total occlusions.
{"title":"Why Treat Chronic Total Occlusion without Stents? - A Short Comment","authors":"P. Köln, F. Kleber","doi":"10.4172/2155-9880.1000529","DOIUrl":"https://doi.org/10.4172/2155-9880.1000529","url":null,"abstract":"The treatment of chronic total occlusions is complex and associated with several risks and problems. Among therapeutic options including bypass surgery and medical therapy PCI represents an important strategy. PCI with stents, however, has limitations in such lesions due to characteristics like lesion length, unknown reference diameter and delayed stent coverage. Drug coated balloons have shown promising properties to overcome some of those limitations: They promote positive vessel remodeling and have a minimal thrombosis rate. In a first multicenter study it has been shown that drug coated balloons in proper indications and applied with appropriate technique might become a new treatment option for patients with chronic total occlusions.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"1 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2017-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75705539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cerebrovascular disease (CVD) accounts for the major cause of morbidity and mortality in industrialized countries. However, effects of high-dose simvastatin therapy on patients with acute cerebral infarction still unclear. In this study, the clinical efficacy of high-dose simvastatin on patients with cerebral infarction was investigated. A total of 180 patients with acute cerebral infarction were randomized divided into control group (n=60), high-dose simvastatin (HDS) group (n=60) and low-dose simvastatin (LDS) group (n=60). Control group, HDS group and LDS group received conventional treatment, conventional treatment together with simvastatin 80 mg/d and conventional treatment as well as simvastatin 40 mg/d respectively for 3 months. Biochemical indices, neurological deficit and plaque thickness and volume were assessed and recorded after treatment. After simvastatin treatment, the plasma levels of Triglyceride, Total cholesterol, Low-density lipoprotein were significantly decreased in HDS group and LDS group, and HDS were significantly increased in HDS group and LDS group. Also, simvastatin decreased levels of IL-6 and TNF-α, two major inflammatory factors in plasma. Furthermore, improved neurological deficit were found in simvastatin treatment groups. In addition, simvastatin treatment also improved plaque states include plaque thickness and volume in HDS group and LDS group. Therefore, simvastatin could improve acute cerebral infarction and high-dose of simvastatin treatment was better than low -dose of simvastatin treatment.
{"title":"The Effect of High-Dose Simvastatin Therapy on Patients with Acute Cerebral Infarction","authors":"Xiaozhu Liu, Huankun Liang, Kangyan Li, Jiali Li, Lai-qing Li, Licheng Zhang","doi":"10.4172/2155-9880.1000527","DOIUrl":"https://doi.org/10.4172/2155-9880.1000527","url":null,"abstract":"Cerebrovascular disease (CVD) accounts for the major cause of morbidity and mortality in industrialized countries. However, effects of high-dose simvastatin therapy on patients with acute cerebral infarction still unclear. In this study, the clinical efficacy of high-dose simvastatin on patients with cerebral infarction was investigated. A total of 180 patients with acute cerebral infarction were randomized divided into control group (n=60), high-dose simvastatin (HDS) group (n=60) and low-dose simvastatin (LDS) group (n=60). Control group, HDS group and LDS group received conventional treatment, conventional treatment together with simvastatin 80 mg/d and conventional treatment as well as simvastatin 40 mg/d respectively for 3 months. Biochemical indices, neurological deficit and plaque thickness and volume were assessed and recorded after treatment. After simvastatin treatment, the plasma levels of Triglyceride, Total cholesterol, Low-density lipoprotein were significantly decreased in HDS group and LDS group, and HDS were significantly increased in HDS group and LDS group. Also, simvastatin decreased levels of IL-6 and TNF-α, two major inflammatory factors in plasma. Furthermore, improved neurological deficit were found in simvastatin treatment groups. In addition, simvastatin treatment also improved plaque states include plaque thickness and volume in HDS group and LDS group. Therefore, simvastatin could improve acute cerebral infarction and high-dose of simvastatin treatment was better than low -dose of simvastatin treatment.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"20 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73789057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-10DOI: 10.4172/2155-9880.1000526
R. Gokhroo, Shashikant Pandey, A. Avinash, Ramsagar, Kailash
Significant unprotected left main coronary artery (ULMCA) disease occurs in 5-7% of patients undergoing coronary angiography [1,2] and patients with ULMCA disease treated medically have a three years mortality rate of 50% [3,4]. Advances in percutaneous intervention techniques and stent technology have allowed evolution of the role of percutaneous coronary intervention (PCI) for left main disease. Left main angioplasty is usually preferred through femoral route because of the larger diameter of the vessel and ease of maneuverability. In recent studies radial route has also been used consistently with better results. Left main coronary angioplasty through ulnar artery route is unheard off. In this case report ulnar access has been used to opine that it is also an alternative, safe, feasible and an additive access to femoral route. Case
{"title":"Trans Ulnar Approach for Unprotected Left Main Coronary Artery Disease","authors":"R. Gokhroo, Shashikant Pandey, A. Avinash, Ramsagar, Kailash","doi":"10.4172/2155-9880.1000526","DOIUrl":"https://doi.org/10.4172/2155-9880.1000526","url":null,"abstract":"Significant unprotected left main coronary artery (ULMCA) disease occurs in 5-7% of patients undergoing coronary angiography [1,2] and patients with ULMCA disease treated medically have a three years mortality rate of 50% [3,4]. Advances in percutaneous intervention techniques and stent technology have allowed evolution of the role of percutaneous coronary intervention (PCI) for left main disease. Left main angioplasty is usually preferred through femoral route because of the larger diameter of the vessel and ease of maneuverability. In recent studies radial route has also been used consistently with better results. Left main coronary angioplasty through ulnar artery route is unheard off. In this case report ulnar access has been used to opine that it is also an alternative, safe, feasible and an additive access to femoral route. Case","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"153 1 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80628835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-03DOI: 10.4172/2155-9880.1000525
T. Rabe, A. Bahekar, S. Arora
Catheter-directed angiography remains the gold standard both for diagnosis and treatment of a coronary artery anomaly (CAA). CAA intervention continues to remains a complicated task even in the hands of experienced operators. The greatest challenges faced in the management of CAAs are delays in identification and difficulty engaging the anomalous coronary artery. Operator experience in promptly identifying the anomaly and selection of the appropriate catheter is critical for successful CAA intervention. We discuss a series of cases where CAAs were encountered during angiography and review the diverse technical difficulties faced by operators during interventions of these congenital anomalies.
{"title":"Challenges of Anomalous Coronary Artery Intervention: Case Series and a Review","authors":"T. Rabe, A. Bahekar, S. Arora","doi":"10.4172/2155-9880.1000525","DOIUrl":"https://doi.org/10.4172/2155-9880.1000525","url":null,"abstract":"Catheter-directed angiography remains the gold standard both for diagnosis and treatment of a coronary artery anomaly (CAA). CAA intervention continues to remains a complicated task even in the hands of experienced operators. The greatest challenges faced in the management of CAAs are delays in identification and difficulty engaging the anomalous coronary artery. Operator experience in promptly identifying the anomaly and selection of the appropriate catheter is critical for successful CAA intervention. We discuss a series of cases where CAAs were encountered during angiography and review the diverse technical difficulties faced by operators during interventions of these congenital anomalies.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"32 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80755701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-27DOI: 10.4172/2155-9880.1000524
Ramsagar Roy, Shashikant Kailash, R. Gokhroo
We report a case of primary coronary angioplasty of left coronary artery through right upper ulnar access with acute lusoria angle due to aberrant right subclavian artery. Although it is very tedious and challenging job to deploy stent in left coronary artery by upper arm access in Arteria lusoria. Hence we propose that PCI is feasible in a case of arteria lusoria by upper right arm access if done with great experience and skill.
{"title":"Primary Percutaneous Coronary Intervention through Right Trans-Ulnar Access in a Case of Arteria Lusoria: Feasibility Stamped","authors":"Ramsagar Roy, Shashikant Kailash, R. Gokhroo","doi":"10.4172/2155-9880.1000524","DOIUrl":"https://doi.org/10.4172/2155-9880.1000524","url":null,"abstract":"We report a case of primary coronary angioplasty of left coronary artery through right upper ulnar access with acute lusoria angle due to aberrant right subclavian artery. Although it is very tedious and challenging job to deploy stent in left coronary artery by upper arm access in Arteria lusoria. Hence we propose that PCI is feasible in a case of arteria lusoria by upper right arm access if done with great experience and skill.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"54 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2017-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84797428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-25DOI: 10.4172/2155-9880.1000523
S. Sajith
Cardiovascular disease is a major health risk since past decade. Surgical treatment for major heart diseases has been one of the major challenges since years. Cardiac valves are synthetic or bio prosthetic ones. Mechanical valves are long durable but highly thrombogenic and undergo calcification at higher rates demanding permanent anticoagulation, which increases the risk of bleeding. Biomaterial scaffolds are used in surgical replacements but only after decellularization and processing. Decellularization makes tissue less antigenic; reduce inflammatory response and less tissue degeneration. In this work two decellularization protocols are tried on bovine pericardium (BP) to find out the effect of each of them on the scaffold's integrity. BP undergone protocol 1(0.25% Trypsin-EDTA, TritonX-100, Deoxycholic acid, Peracetic acid/Ethanol) treatment was seen to have highly distorted and damaged collagen matrix. Decellularization with protocol 2 (Deoxycholic acid, DNase, RNase, Ethanol) resulted in a completely decellularised bovine pericardium. The extracellular matrix was intact as native one with collagen bundles. This will help cell attachment to the decellularised matrix.
{"title":"Comparative Study of Two Decellularization Protocols on a Biomaterial for Tissue Engineering","authors":"S. Sajith","doi":"10.4172/2155-9880.1000523","DOIUrl":"https://doi.org/10.4172/2155-9880.1000523","url":null,"abstract":"Cardiovascular disease is a major health risk since past decade. Surgical treatment for major heart diseases has been one of the major challenges since years. Cardiac valves are synthetic or bio prosthetic ones. Mechanical valves are long durable but highly thrombogenic and undergo calcification at higher rates demanding permanent anticoagulation, which increases the risk of bleeding. Biomaterial scaffolds are used in surgical replacements but only after decellularization and processing. Decellularization makes tissue less antigenic; reduce inflammatory response and less tissue degeneration. In this work two decellularization protocols are tried on bovine pericardium (BP) to find out the effect of each of them on the scaffold's integrity. BP undergone protocol 1(0.25% Trypsin-EDTA, TritonX-100, Deoxycholic acid, Peracetic acid/Ethanol) treatment was seen to have highly distorted and damaged collagen matrix. Decellularization with protocol 2 (Deoxycholic acid, DNase, RNase, Ethanol) resulted in a completely decellularised bovine pericardium. The extracellular matrix was intact as native one with collagen bundles. This will help cell attachment to the decellularised matrix.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"12 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87716254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-20DOI: 10.4172/2155-9880.1000522
A. Ledakowicz-Polak, J. SÅawomir, er, M. Kidawa, K. Stokfisz, Marzenna ZieliÅska
Ventricular septal rupture is still a rare but often fatal complication of acute myocardial infarction. Emergent surgical closure of postinfarction ventricular septal rupture irrespective of the clinical status has been the standard treatment so far. A percutaneous approach using an occluder device is a less invasive option and allows immediate complete closure after initial hemodynamic stabilization. Furthermore immediate reduction of the left-to-right shunt, even if the ventricular septal rupture is not completely closed, may stabilize the patient enough to function as a bridge to surgery. We present two similar cases of patients which highlight the multiple features of acute myocardial infarction- related ventricular septal rupture treated with two alternative techniques.
{"title":"Ventricular Septal Rupture After Acute Myocardial Infarction-Do We Know Which Strategy to Choose?","authors":"A. Ledakowicz-Polak, J. SÅawomir, er, M. Kidawa, K. Stokfisz, Marzenna ZieliÅska","doi":"10.4172/2155-9880.1000522","DOIUrl":"https://doi.org/10.4172/2155-9880.1000522","url":null,"abstract":"Ventricular septal rupture is still a rare but often fatal complication of acute myocardial infarction. Emergent surgical closure of postinfarction ventricular septal rupture irrespective of the clinical status has been the standard treatment so far. A percutaneous approach using an occluder device is a less invasive option and allows immediate complete closure after initial hemodynamic stabilization. Furthermore immediate reduction of the left-to-right shunt, even if the ventricular septal rupture is not completely closed, may stabilize the patient enough to function as a bridge to surgery. We present two similar cases of patients which highlight the multiple features of acute myocardial infarction- related ventricular septal rupture treated with two alternative techniques.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"9 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87260674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-20DOI: 10.4172/2155-9880.1000519
M. Saghiv, Chris Sherve, D. Sira, M. Saghiv, E. Goldhammer
Purpose: The present study looked at gender difference in oxygen delivery-extraction at maximal oxygen uptake in healthy adolescents. Methods: 36 adolescent males (14.9 ± 1.1 years) and 33 adolescent females (15.0 ± 1.1 years) underwent a maximal oxygen uptake test and a two dimensional direct m-mode echocardiography performed on a bicycle ergometry. Arteriovenous oxygen difference was defined by utilizing the Fick equation. Results: At rest, males compared to females had significantly (p<0.05) higher oxygen extraction (38.8 ± 1.4 and 31.8 ± 1.2 mL.kg-1 .min-1 respectively), systolic blood pressure, and mean arterial blood pressure. At peak exercise test, males compared to females demonstrated significant (P<0.05) higher values for cardiac output (16.6 ± 0.7 and 15.4 ± 0.6 L∙min-1 respectively), stroke volume (83.9 ± 5.1 and 78.5 ± 4.6 mL respectively), oxygen uptake (47.3 ± 3.7 and 39.6 ± 1.1 mL∙kg-1∙min-1, respectivel y), while oxygen extraction was significantly higher in females compared to males (123.6 ± 7.6 and 115.5 ± 5.4 mL∙L-1 respectively). Conclusions: This study suggests that normal adolescents; male and females respond to the maximal oxygen uptake test by increased their left ventricular systolic function, however, it was less augmented in the females due to gender and energy metabolism differences. Consequently, females increased their oxygen extraction more than the males as a compensation for the lower cardiac output and hence, lower oxygen delivery.
{"title":"Are there Differences between Adolescent Males and Females for Maintaining the Metabolic Cost at Maximal Oxygen Uptake","authors":"M. Saghiv, Chris Sherve, D. Sira, M. Saghiv, E. Goldhammer","doi":"10.4172/2155-9880.1000519","DOIUrl":"https://doi.org/10.4172/2155-9880.1000519","url":null,"abstract":"Purpose: The present study looked at gender difference in oxygen delivery-extraction at maximal oxygen uptake \u0000 in healthy adolescents. \u0000Methods: 36 adolescent males (14.9 ± 1.1 years) and 33 adolescent females (15.0 ± 1.1 years) underwent \u0000 a maximal oxygen uptake test and a two dimensional direct m-mode echocardiography performed on a bicycle \u0000 ergometry. Arteriovenous oxygen difference was defined by utilizing the Fick equation. \u0000Results: At rest, males compared to females had significantly (p<0.05) higher oxygen extraction (38.8 ± 1.4 and \u0000 31.8 ± 1.2 mL.kg-1 .min-1 respectively), systolic blood pressure, and mean arterial blood pressure. At peak exercise \u0000 test, males compared to females demonstrated significant (P<0.05) higher values for cardiac output (16.6 ± 0.7 and \u0000 15.4 ± 0.6 L∙min-1 respectively), stroke volume (83.9 ± 5.1 and 78.5 ± 4.6 mL respectively), oxygen uptake (47.3 ± 3.7 \u0000 and 39.6 ± 1.1 mL∙kg-1∙min-1, respectivel y), while oxygen extraction was significantly higher in females compared to \u0000 males (123.6 ± 7.6 and 115.5 ± 5.4 mL∙L-1 respectively). \u0000Conclusions: This study suggests that normal adolescents; male and females respond to the maximal oxygen \u0000 uptake test by increased their left ventricular systolic function, however, it was less augmented in the females due to \u0000 gender and energy metabolism differences. Consequently, females increased their oxygen extraction more than the \u0000 males as a compensation for the lower cardiac output and hence, lower oxygen delivery.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"9 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87960704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-20DOI: 10.4172/2155-9880.1000520
Schleder S, Diekmann M, Manke C, Heiss P
Background: Since its introduction, percutaneous aspiration embolectomy (PAE) has become a well-known, widely accepted and frequently applied technique for the treatment of acute arterial embolic infrainguinal vascular occlusion in lower limb ischemia.Purpose: To evaluate the technical and clinical success of sole percutaneous aspiration embolectomy (PAE) for the treatment of acute arterial embolic infrainguinal vascular occlusion.Material and Methods: During a period of 7 years, 50 patients (24 fermale, 48%) with a mean age of 73 (range 53–95) years were identified in whom 54 cases of PAE were performed for the treatment of arterial embolic infrainguinal vascular occlusion. Primary technical success was defined as residual stenosis of <50% in diameter after sole PAE, secondary technical success was defined as residual stenosis of <50% in diameter after PAE and additional percutaneous transluminal angioplasty (PTA) and/or stenting. Clinical outcome parameters (e.g. need for further intervention and/or amputation) were evaluated for the 30-day postinterventional period.Results: The primary technical success rate was 85% (46 of 54 cases). The secondary technical success rate was 96% (52 of 54 cases). Clinical outcome data were achievable in 50 of the 54 cases (93%). In 43 of the 50 patients (86%) there was no need for further intervention within the 30-day postinterventional period. In summary, during this 30-day postinterventional period after PAE amputation was carried out or death occurred in 5 of 50 patients (10%).Conclusion: Minimally invasive PAE is an effective and safe technique for the treatment of acute arterial embolic infrainguinal vascular occlusion.
{"title":"Percutaneous Aspiration Embolectomy in the Treatment of Acute Arterial Embolic Infrainguinal Vascular Occlusion","authors":"Schleder S, Diekmann M, Manke C, Heiss P","doi":"10.4172/2155-9880.1000520","DOIUrl":"https://doi.org/10.4172/2155-9880.1000520","url":null,"abstract":"Background: Since its introduction, percutaneous aspiration embolectomy (PAE) has become a well-known, widely accepted and frequently applied technique for the treatment of acute arterial embolic infrainguinal vascular occlusion in lower limb ischemia.Purpose: To evaluate the technical and clinical success of sole percutaneous aspiration embolectomy (PAE) for the treatment of acute arterial embolic infrainguinal vascular occlusion.Material and Methods: During a period of 7 years, 50 patients (24 fermale, 48%) with a mean age of 73 (range 53–95) years were identified in whom 54 cases of PAE were performed for the treatment of arterial embolic infrainguinal vascular occlusion. Primary technical success was defined as residual stenosis of <50% in diameter after sole PAE, secondary technical success was defined as residual stenosis of <50% in diameter after PAE and additional percutaneous transluminal angioplasty (PTA) and/or stenting. Clinical outcome parameters (e.g. need for further intervention and/or amputation) were evaluated for the 30-day postinterventional period.Results: The primary technical success rate was 85% (46 of 54 cases). The secondary technical success rate was 96% (52 of 54 cases). Clinical outcome data were achievable in 50 of the 54 cases (93%). In 43 of the 50 patients (86%) there was no need for further intervention within the 30-day postinterventional period. In summary, during this 30-day postinterventional period after PAE amputation was carried out or death occurred in 5 of 50 patients (10%).Conclusion: Minimally invasive PAE is an effective and safe technique for the treatment of acute arterial embolic infrainguinal vascular occlusion.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"11 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84902888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-20DOI: 10.4172/2155-9880.1000521
M. H. Makki
In 1908, McMurrich described the presence of strictures in the common iliac vein that were believed to be responsible for the increased incidence of left leg deep-vein thrombosis (DVT). This syndrome would eventually become known as iliac vein compression syndrome or May-Thurner Syndrome (MTS). Left iliac vein compression from the contralateral right common iliac artery, against the posterior fifth lumbar vertebral body, is estimated to comprise 49% to 62% of cases of left lower extremity disease.
{"title":"One, Two, Three: Stepwise Treatment of a Large DVT in a 53 Year Old Femalewith May-Thurner","authors":"M. H. Makki","doi":"10.4172/2155-9880.1000521","DOIUrl":"https://doi.org/10.4172/2155-9880.1000521","url":null,"abstract":"In 1908, McMurrich described the presence of strictures in the common iliac vein that were believed to be responsible for the increased incidence of left leg deep-vein thrombosis (DVT). This syndrome would eventually become known as iliac vein compression syndrome or May-Thurner Syndrome (MTS). Left iliac vein compression from the contralateral right common iliac artery, against the posterior fifth lumbar vertebral body, is estimated to comprise 49% to 62% of cases of left lower extremity disease.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"70 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85983377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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