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Progress Toward the Elimination of Vertical HIV Transmission in Nepal: A Retrospective Cohort Study. 尼泊尔消除艾滋病毒垂直传播的进展:一项回顾性队列研究。
IF 2.2 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-12-01 Epub Date: 2025-07-01 DOI: 10.1007/s10900-025-01474-6
Upendra Shrestha, Lok Raj Pandey, Man Bahadur Kc, Ali Mirzazadeh, Keshab Deuba

Despite global advancements, pregnant women living with HIV in Nepal remain at risk for vertical transmission. This study examined demographic and clinical characteristics, antiretroviral therapy (ART) retention, and transmission outcomes among this population. A retrospective cohort analysis was conducted using data from Nepal's national electronic HIV register, including 322 women who became pregnant between 2020 and 2023. We analyzed sociodemographic profiles, clinical status at diagnosis, ART initiation timing, retention rates at 6, 12, and 24 months, and infant HIV status. The mean age was 26.9 years; over half (56.2%) were aged 25-39 years. Nearly 40% were illiterate, 87.6% unemployed, and 66.8% reported unsafe sexual behavior as the mode of HIV transmission. Over half (58.1%) were diagnosed prior to pregnancy, and 75.5% were in WHO Stage 1. ART began on the same day in 34.8% and within a week in 40.1%, with 56.8% already on ART during pregnancy. Retention was high: 96.9% at 6 months, 94.8% at 12 months, and 96.0% at 24 months. Vertical transmission occurred in 4.3% of pregnancies. Higher transmission rates were observed among younger mothers (6.9%), Dalit women (11.5%), those in advanced HIV stages (11.1%), with delayed ART initiation (8.6%), high viral loads (13.3%), and home deliveries (17.6%). In Nepal, approximately 1 in 23 infants born to women living with HIV still acquire the infection. Strengthening early diagnosis, improving ART uptake, and addressing disparities in care especially among high-risk groups are essential to eliminating vertical transmission and improving maternal and child health outcomes.

尽管全球取得了进展,但尼泊尔感染艾滋病毒的孕妇仍然面临垂直传播的风险。这项研究调查了人口统计学和临床特征,抗逆转录病毒治疗(ART)的保留和传播结果。利用尼泊尔国家电子艾滋病毒登记处的数据进行了回顾性队列分析,其中包括2020年至2023年间怀孕的322名妇女。我们分析了社会人口学概况、诊断时的临床状况、开始抗逆转录病毒治疗的时间、6个月、12个月和24个月的保留率以及婴儿艾滋病毒状况。平均年龄26.9岁;超过一半(56.2%)的患者年龄在25-39岁之间。近40%的人是文盲,87.6%的人没有工作,66.8%的人报告不安全的性行为是艾滋病毒的传播方式。超过一半(58.1%)在怀孕前被诊断出来,75.5%处于世卫组织第一阶段。34.8%的人在同一天开始接受抗逆转录病毒治疗,40.1%的人在一周内开始接受抗逆转录病毒治疗,56.8%的人在怀孕期间已经接受了抗逆转录病毒治疗。留存率很高:6个月时为96.9%,12个月时为94.8%,24个月时为96.0%。垂直传播发生率为4.3%。在年轻母亲(6.9%)、达利特妇女(11.5%)、艾滋病毒晚期(11.1%)、延迟开始抗逆转录病毒治疗(8.6%)、高病毒载量(13.3%)和在家分娩(17.6%)中观察到较高的传播率。在尼泊尔,大约每23名携带艾滋病毒的妇女所生的婴儿中就有1名仍然感染艾滋病毒。加强早期诊断,改善抗逆转录病毒治疗,解决特别是高危人群在护理方面的差异,对于消除垂直传播和改善孕产妇和儿童健康结果至关重要。
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引用次数: 0
A Novel Pharmaceutical Program for Uninsured Patients at a Free Clinic. 在免费诊所为没有保险的病人提供新的药物计划。
IF 2.2 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-12-01 Epub Date: 2025-06-26 DOI: 10.1007/s10900-025-01498-y
Karen Ha, Maria Giraldo, Jorge Garavito, Ross Hilliard

The escalating cost of medications has rendered them increasingly unaffordable, particularly for uninsured and underinsured individuals. Free clinics often serve as vital safety nets for these medically vulnerable populations, offering low-cost or free healthcare and medications. However, these programs often grapple with issues of scalability and sustainability due to limited resources. This study examines the implementation of a novel pharmaceutical program at the Rhode Island Free Clinic, designed to establish a sustainable, charitably-sourced medication program for around 2,000 uninsured patients. Anonymous surveys of 99 patients conducted before and after the program's introduction revealed a marked improvement in medication access. The proportion of patients who found obtaining medications "very difficult" declined from 36% pre-intervention to 9% post-intervention. This initiative distinguishes itself through strategic partnerships with existing programs, fostering a patient-centered approach that prioritizes medication accessibility while minimizing the operational burden on any single organization. While challenges remain, initiatives like this represent a crucial step toward bridging gaps in the current landscape of American healthcare, ultimately contributing to healthier communities, reduced medical expenditure, and a more equitable healthcare system.

不断上涨的药物费用使它们越来越难以负担,特别是对于没有保险和保险不足的个人。免费诊所往往是这些医疗弱势群体的重要安全网,提供低成本或免费的医疗保健和药物。然而,由于资源有限,这些程序经常面临可扩展性和可持续性的问题。本研究考察了罗德岛免费诊所(Rhode Island Free Clinic)一项新型药物计划的实施情况,该计划旨在为约2000名未参保患者建立一个可持续的、慈善来源的药物计划。在项目实施前后对99名患者进行的匿名调查显示,在药物获取方面有了显著改善。发现获得药物“非常困难”的患者比例从干预前的36%下降到干预后的9%。该计划通过与现有项目的战略合作伙伴关系脱颖而出,培养以患者为中心的方法,优先考虑药物可及性,同时最大限度地减少任何单个组织的运营负担。尽管挑战依然存在,但像这样的举措代表了弥合美国医疗保健现状差距的关键一步,最终有助于建立更健康的社区,减少医疗支出,建立更公平的医疗保健系统。
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引用次数: 0
Beyond Locks and Lectures: What Rural Parents Think Would Be Effective Firearm Safety Messaging and Programming. 超越锁和讲座:农村父母认为有效的枪支安全信息和编程。
IF 2.2 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-11-27 DOI: 10.1007/s10900-025-01533-y
Victor A Soupene, Charles Jennissen, Nicholas Stange, Pam Hoogerwerf, Cassidy Branch, Marc Doobay

Firearm-related suicides and unintentional injuries occur at higher rates in rural U.S. communities than in urban areas. While safe storage programs may help reduce these injuries, little is known about how to effectively engage rural, farming populations. This study aimed to identify factors influencing firearm safety programming and messaging among parents in rural households. Focus groups were conducted in 2024 with rural Iowa parents recruited via FFA club advisors and through the University of Iowa mass e-mail system. Inclusion criteria included: (1) residence in Iowa with active farming or ranching operations, (2) at least one child aged 10-19 living in the home, and (3) at least one firearm in the household. Discussions followed a moderator guide to identify primary themes, with sub-themes emerging organically. Transcripts were analyzed using Dedoose software. Three researchers independently coded the data and resolved discrepancies through consensus. Thirty-two participants identified trusted messengers as law enforcement, Department of Natural Resources personnel, and community members affected by firearm violence. Teachers, healthcare professionals, and celebrities were viewed as less credible. Participants emphasized age-specific messaging using realistic examples and visuals and suggested integrating firearm safety into existing programs like school curricula, 4-H, FFA and local safety courses. Views on distributing safety devices like locks and safes were mixed. Tailoring firearm safety interventions to reflect the values and preferences of rural communities may improve engagement and effectiveness. Strategies led by trusted local messengers may be particularly impactful.

与城市地区相比,美国农村地区与枪支有关的自杀和意外伤害发生率更高。虽然安全储存计划可能有助于减少这些伤害,但人们对如何有效地吸引农村农业人口知之甚少。本研究旨在确定影响农村家庭中父母枪支安全规划和信息传递的因素。焦点小组于2024年通过FFA俱乐部顾问和爱荷华大学的大众电子邮件系统招募了爱荷华州农村的父母。纳入标准包括:(1)居住在爱荷华州并从事农业或牧场经营,(2)家中至少有一名10-19岁的儿童,以及(3)家中至少有一支枪支。讨论遵循主持人指南来确定主要主题,并有组织地出现次级主题。转录本用Dedoose软件分析。三位研究人员独立地对数据进行编码,并通过共识解决差异。32名参与者将执法人员、自然资源部人员和受枪支暴力影响的社区成员确定为可信的信使。教师、医疗专业人员和名人被认为不那么可信。与会者强调使用真实的例子和视觉效果来传达针对年龄的信息,并建议将枪支安全纳入现有的课程,如学校课程、4-H、FFA和地方安全课程。对于发放锁和保险柜等安全设备,意见不一。调整枪支安全干预措施,以反映农村社区的价值观和偏好,可能会提高参与度和有效性。由值得信赖的当地信使领导的战略可能特别有影响力。
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引用次数: 0
Involving Latinas in Understanding Barriers, Facilitators, and Appropriate Outreach for Mammography in Tacoma, Washington, USA. 让拉丁裔了解美国华盛顿州塔科马市乳房x光检查的障碍、促进者和适当外展。
IF 2.2 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-11-27 DOI: 10.1007/s10900-025-01541-y
Kendra Lopez, Marleny Silva, Katherine J Briant, Barb Fox, Craig Dee, Rachel M Ceballos, Beti Thompson

Breast cancer screening rates are lower for Hispanic females (Latinas) than their non-Hispanic White counterparts. This discrepancy is partly due to health disparities, such as limited access to care, inability to take time off work, lack of health insurance, and cultural and emotional barriers. In response to a health department request, the Carol Milgard Breast Center conducted a qualitative assessment, as part of a community grant pilot award from Fred Hutchinson Cancer Center, to better understand the barriers and facilitators influencing Latinas' participation in mammography screening. The objective was to identify key characteristics of an intervention aimed at encouraging mammogram uptake among Latinas. Forty women were recruited and consented to participate in structured interviews, which included questions on their perceptions of mammography. The interviews explored structural barriers (e.g., lack of insurance), cultural issues (e.g., prioritizing family over individual health), and emotional concerns (e.g., fear of embarrassment). By detailing lessons learned and community identified outreach strategies, this work advances the evidence base on community engagement with Latinas for cancer education and outreach. Findings underscore the need for linguistically and culturally tailored resources, trusted messengers, and outreach approaches that meet Latinas where they are. The identified strategies can inform interventions to improve mammography uptake in similar communities and guide larger-scale implementation efforts.

西班牙裔女性(拉丁裔)的乳腺癌筛查率低于非西班牙裔白人。造成这种差异的部分原因是健康差异,例如获得护理的机会有限、无法休假、缺乏医疗保险以及文化和情感障碍。为了响应卫生部的要求,Carol Milgard乳房中心进行了定性评估,作为Fred Hutchinson癌症中心社区拨款试点奖励的一部分,以更好地了解影响拉丁裔参与乳房x光检查的障碍和促进因素。目的是确定旨在鼓励拉丁美洲人接受乳房x光检查的干预措施的关键特征。招募了40名妇女并同意参加结构化访谈,其中包括关于她们对乳房x光检查的看法的问题。访谈探讨了结构性障碍(例如,缺乏保险)、文化问题(例如,将家庭置于个人健康之上)和情感问题(例如,害怕尴尬)。通过详细介绍经验教训和社区确定的外展战略,这项工作推进了社区参与拉丁裔癌症教育和外展的证据基础。调查结果强调,需要根据语言和文化量身定制资源、可信赖的信使以及满足拉丁美洲人需求的外展方法。确定的战略可以为干预措施提供信息,以提高类似社区的乳房x光检查使用率,并指导更大规模的实施工作。
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引用次数: 0
Influenza Vaccine Uptake in the Elderly: Biopsychosocial Vulnerabilities and Effectiveness of a Community-Health Worker Administered Preventive Program. 老年人流感疫苗接种:社区卫生工作者管理的预防计划的生物心理社会脆弱性和有效性。
IF 2.2 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-11-27 DOI: 10.1007/s10900-025-01512-3
Adrian Ujin Yap, Jia Yi Chee, Hee Hoon Lee, Thong Gan Chee, Jesslyn Hwei Sing Chong

This quasi-experimental study examined the biopsychosocial (BPS) vulnerabilities of non-vaccinated elderly individuals, evaluated the effectiveness of community health workers (CHWs) in improving influenza vaccine uptake, and assessed the impact of a CHW-administered community-based health intervention (CBHI) on health-related quality of life (HRQoL). Pre- and post-intervention data were collected from participants enrolled in the "Get Well, Live Well" (GWLW) program. As part of this CBHI, hospital-employed CHWs applied various interventions to improve influenza vaccine awareness, accessibility, and timely administration. The BPS risk screener and EQ5D-3L were used to assess the individuals' initial biopsychosocial vulnerabilities and pre/post-program HRQoL respectively through face-to-face and telephone interviews. Influenza vaccination rates were computed and data were analyzed utilizing Chi-square and non-parametric tests, along with logistic regression analysis (α = 0.05). The final sample (n = 229) had a mean age of 73.15 ± 5.6 years and comprised 68.1% women and 87.8% Chinese. Non-vaccinated individuals were found to be younger and exhibited significantly greater social health risk and poorer self-rated health than their vaccinated counterparts. Multivariate analysis revealed that age was the primary predictor of non-vaccination (OR = 0.94; 95% CI = 0.90-0.99). The CHW-administered GWLW program doubled influenza vaccination rates (30.1-60.7%) and significantly improved the summary index, self-rated health, and prevalence of no pain/discomfort among the elderly. CBHIs, administered by hospital-employed non-medical CHWs, proved effective in improving influenza vaccination rates and elevating HRQoL. Future influenza vaccination efforts should prioritize socio-interpersonal interventions for the younger elderly.

这项准实验研究检查了未接种疫苗的老年人的生物心理社会(BPS)脆弱性,评估了社区卫生工作者(CHWs)在提高流感疫苗吸收方面的有效性,并评估了社区卫生工作者管理的社区卫生干预(CBHI)对健康相关生活质量(HRQoL)的影响。干预前和干预后的数据收集自参加“健康生活”(GWLW)项目的参与者。作为该计划的一部分,医院聘用的卫生保健员采用了各种干预措施,以提高流感疫苗的认识、可及性和及时给药。采用BPS风险筛查和EQ5D-3L分别通过面对面和电话访谈评估个体的初始生物心理社会脆弱性和项目前/后HRQoL。计算流感疫苗接种率,采用卡方检验、非参数检验和logistic回归分析(α = 0.05)对数据进行分析。最终样本(n = 229)平均年龄为73.15±5.6岁,女性占68.1%,中国人占87.8%。未接种疫苗的人比接种疫苗的人更年轻,表现出更大的社会健康风险和更差的自我评价健康。多因素分析显示,年龄是未接种疫苗的主要预测因素(OR = 0.94; 95% CI = 0.90-0.99)。chw管理的GWLW项目使流感疫苗接种率增加了一倍(30.1-60.7%),并显著改善了总结指数、自我评估健康状况和老年人无疼痛/不适的患病率。事实证明,由医院雇用的非医疗保健员管理的cbhs在提高流感疫苗接种率和提高HRQoL方面是有效的。未来的流感疫苗接种工作应优先考虑对较年轻的老年人进行社会人际干预。
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引用次数: 0
Limited Awareness and Persistent Barriers To Crime Victims Compensation in Violently Injured Patients. 暴力伤害患者对犯罪受害者赔偿的认识不足和持续障碍。
IF 2.2 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-11-27 DOI: 10.1007/s10900-025-01537-8
Andrew T Labott, Emily Cooper, Anna Tatakis, Elise A Biesboer, Ariel F Berry, Yara Hamadeh, Quinn Anderson, Amber Brandolino, Terri A deRoon-Cassini, Mary E Schroeder

Violent injury imposes substantial economic, health, and social burdens on survivors, yet little is known about awareness and access to state-run Crime Victims Compensation (CVC) programs among those most affected. This study examined CVC awareness, application patterns, and barriers among violently injured patients at an urban Level I trauma center. We conducted a prospective cohort study of adults (≥ 18 years) admitted between February 1, 2024 and February 1, 2025 for injuries due to firearm assault, pedestrian-motor vehicle collision, physical assault, or reckless injury. Data from the electronic medical record, participant surveys, and the Wisconsin Department of Justice CVC database were analyzed to identify factors associated with CVC application and outcomes. Of 2,200 trauma patients screened, 141 were enrolled. Participants were predominantly male (74%) and Black (68%), with 62% residing in neighborhoods in the highest deciles of socioeconomic disadvantage. Only 9% were aware of the CVC program prior to enrollment, yet 50% applied for funds. Applicants were more likely to be younger, Black, employed, and survivors of gunshot wounds. Among applicants, 55% were approved and 30% denied; delinquent child support accounted for 67% of denials, and discomfort engaging with law enforcement for 14%. Most participants (93%) anticipated injury-related costs (median $1,500). CVC awareness among violently injured patients remains extremely low. Integrating CVC education and assistance into hospital workflows and reforming punitive eligibility criteria are essential to promote equitable financial recovery and community reintegration after violent injury.

暴力伤害给幸存者带来了巨大的经济、健康和社会负担,但人们对受影响最严重的人的意识和获得国家犯罪受害者赔偿(CVC)计划的途径知之甚少。本研究调查了城市一级创伤中心暴力伤害患者对CVC的认知、应用模式和障碍。我们对2024年2月1日至2025年2月1日期间因枪支攻击、行人与机动车碰撞、人身攻击或鲁莽伤害而入院的成年人(≥18岁)进行了一项前瞻性队列研究。分析了来自电子病历、参与者调查和威斯康星州司法部CVC数据库的数据,以确定与CVC应用和结果相关的因素。在2200名接受筛选的创伤患者中,有141人入选。参与者主要是男性(74%)和黑人(68%),其中62%居住在社会经济劣势最高的十分之一的社区。只有9%的人在入学前知道CVC项目,但50%的人申请了资金。申请者更有可能是年轻的、有工作的黑人和枪伤幸存者。在申请人中,55%被批准,30%被拒绝;拖欠子女抚养费占拒绝的67%,与执法部门接触时感到不适占14%。大多数参与者(93%)预计受伤相关费用(中位数为1,500美元)。暴力受伤患者对CVC的认识仍然极低。将暴力伤害教育和援助纳入医院工作流程,并改革惩罚性资格标准,对于促进暴力伤害后公平的经济恢复和重返社区至关重要。
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引用次数: 0
An Mpox 2024 Survey of Health Sciences Students in India and Bangladesh. 印度和孟加拉国卫生科学专业学生Mpox 2024调查。
IF 2.2 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-11-27 DOI: 10.1007/s10900-025-01540-z
ArunSundar MohanaSundaram, Kalpana Singh, Mohammad Sidiq, Jyoti Sharma, Ashek Elahi Noor, Sushmita Shivanna, Lakshmi Kanthan, Md Ariful Haque

The World Health Organization (WHO) has declared public health emergency of international concern (PHEIC) for the multinational outbreak of mpox in 2024, due to clade I Monkeypox virus (MPXV). Our team conducted a questionnaire-based cross-sectional study to investigate the knowledge and attitudes of 902 health science students (who were studying dentistry, physiotherapy, pharmacy, or nursing) in India and Bangladesh. The mean knowledge and attitude scores were 14.4 ± 3.6 and 7.7 ± 1.9, respectively. Despite high (> 85%) awareness of Mpox outbreaks and cognizance of the declaration of PHEIC, noteworthy misconceptions were also noticed: 55.9% thought that MPXV infection could be treated with antibiotics, and there was an increased case fatality estimation. Approximately 91% of students preferred post-infection isolation and relied on vaccination. Nearly three-fourths of them were concerned about the pandemic potential of MPXV. Based on the multivariable models, we found that students ≥ 26 years of age (β = 2.23; 95% CI 0.97-3.50) and those with prior information-seeking behavior through Google, ChatGPT, etc. (β = 1.46; 0.97-1.96) independently predicted higher knowledge. These patterns were also observed for attitudes (β = 0.84, 0.23-1.45). Interns/residents showed better scores, while third-year students displayed lower knowledge (β = -1.42; -2.75 to - 0.09). These findings show that there is scope for readiness, but there are gaps in therapeutic and risk management. This study underscores the need for incremental activities to augment digital and curricular literacy for combating public health emergencies in low-resource academic milieu.

世界卫生组织(世卫组织)宣布,由于猴痘I支病毒(MPXV)导致的2024年多国暴发的mpox,是国际关注的突发公共卫生事件。我们的团队进行了一项基于问卷的横断面研究,以调查印度和孟加拉国902名健康科学学生(他们正在学习牙科、物理治疗、药学或护理)的知识和态度。平均知识和态度得分分别为14.4±3.6分和7.7±1.9分。尽管对麻疹暴发和宣布为国际关注的突发公共卫生事件有很高的认识(约85%),但也注意到值得注意的误解:55.9%的人认为MPXV感染可以用抗生素治疗,并且病死率估计有所增加。大约91%的学生倾向于感染后隔离并依赖于疫苗接种。其中近四分之三的人担心MPXV可能会大流行。基于多变量模型,我们发现≥26岁的学生(β = 2.23; 95% CI 0.97-3.50)和通过谷歌、ChatGPT等有先验信息寻求行为的学生(β = 1.46; 0.97-1.96)独立预测更高的知识。这些模式也被观察到的态度(β = 0.84, 0.23-1.45)。实习生/住院医师的得分较高,而三年级学生的知识水平较低(β = -1.42; -2.75 ~ - 0.09)。这些发现表明,有准备的余地,但在治疗和风险管理方面存在差距。本研究强调需要开展渐进式活动,以增强数字和课程素养,以应对资源匮乏的学术环境中的突发公共卫生事件。
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引用次数: 0
Community Needs Assessment for Understanding the Health and Social Needs for South Asian Immigrant Populations in Southeast Queens County, New York City, Across Levels of English Proficiency. 社区需求评估以了解纽约市东南皇后县南亚移民人口的健康和社会需求,不分英语熟练程度。
IF 2.2 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-11-27 DOI: 10.1007/s10900-025-01534-x
Nowshin Mannan, Afsana Monir, Shivani Mishra, Sarah Li, Nari Yoo, Naheed Ahmed

South Asian immigrants in Southeast Queens County, New York City face healthcare, housing, and digital access challenges shaped by English proficiency. Despite community growth, data remains limited. This assessment examines English proficiency as a social determinant of health. A mixed-methods study was conducted across nine ZIP codes in Southeast Queens County, New York City. From August 1-October 31, 2023, the quantitative phase included a multilingual survey (English, Bengali, Hindi) that reached 395 South Asian participants, covering demographics, living conditions, food security, safety, mental health, and digital literacy. The qualitative phase (December 2023-March 2024), guided by IDEO's Human-Centered Design, included five interviews and a focus group. Analysis revealed significant disparities between Limited English Proficiency (LEP, n = 288) and non-LEP (n = 107) individuals. LEP respondents reported more housing issues, especially pest infestations (91.1% vs. 82.4%, p = 0.042), and lower homeownership (19.1% vs. 34.6%, p = 0.031). Computer literacy was lower among LEP individuals (50.6% vs. 80.8%, p < 0.001), though internet access was high in both groups (87.0% for LEP vs. 91.4% for non-LEP, p = 0.24). Housing instability persisted, with a greater share of LEP participants renting (70.6% vs. 56.4%, p = 0.031). This assessment highlights how language proficiency shapes social determinants of health for South Asian immigrants in Southeast Queens County, New York City. LEP individuals faced more housing, food, safety, and digital literacy challenges, underscoring the need for language-accessible, culturally tailored services.

纽约市东南皇后县的南亚移民面临着由英语熟练程度决定的医疗、住房和数字访问方面的挑战。尽管社区在增长,但数据仍然有限。本评估考察英语熟练程度作为健康的社会决定因素。一项混合方法的研究在纽约市东南皇后县的九个邮政编码区进行。从2023年8月1日至10月31日,定量阶段包括一项多语言调查(英语、孟加拉语、印地语),共有395名南亚参与者参与,内容涵盖人口统计、生活条件、粮食安全、安全、心理健康和数字素养。定性阶段(2023年12月至2024年3月),以IDEO的“以人为本的设计”为指导,包括五次访谈和一个焦点小组。分析显示有限英语水平(LEP, n = 288)和非LEP (n = 107)个体之间存在显著差异。LEP受访者报告了更多的住房问题,特别是害虫侵扰(91.1%对82.4%,p = 0.042),以及较低的住房拥有率(19.1%对34.6%,p = 0.031)。LEP个体的计算机素养较低(50.6% vs. 80.8%, p
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引用次数: 0
Prevalence and Factors Associated with Non-Adherence To Anti-retroviral Therapy among People Living with HIV. 艾滋病毒感染者中不坚持抗逆转录病毒治疗的流行率和相关因素
IF 2.2 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-11-27 DOI: 10.1007/s10900-025-01536-9
Meshack Morice, Maria Niwe Kalikawe, Amina Killo Lussewa, Timothy Paul Oyoo

Non-adherence to antiretroviral therapy (ART) remains a major barrier to achieving viral suppression and HIV epidemic control, particularly in sub-Saharan Africa. Despite significant ART coverage in Tanzania, a substantial proportion of people living with HIV (PLHIV) fail to achieve optimal adherence, leading to drug resistance, treatment failure, and increased morbidity. This study determined the prevalence and factors associated with ART non-adherence among PLHIV. A cross-sectional study was conducted among 309 PLHIV receiving ART at Mwananyamala Hospital. Participants were selected through simple random sampling. Data were collected using structured questionnaires and medical record reviews, and analysed using SPSS version 26. Descriptive statistics determined prevalence, while bivariate and multivariate logistic regression identified associated factors. Odds ratios (ORs), 95% confidence intervals (CIs), and p-values < 0.05 were used to determine statistical significance. The prevalence of ART non-adherence was 35.3%. Participants aged ≥ 45 years were more likely to be non-adherent (AOR = 2.52, 95% CI: 0.98,6.52, p = 0.046). Longer ART duration (> 5 years) was also significantly associated with non-adherence (AOR = 1.75, 95% CI: 0.97,3.15, p = 0.041). Forgetfulness emerged as another determinant (AOR = 1.28, 95% CI: 0.36,2.87, p = 0.017). Other factors such as stigma, social support, and alcohol use had no significant association with non-adherence. Over one-third of PLHIV at Mwananyamala Hospital were non-adherent to ART. Targeted interventions addressing treatment fatigue, forgetfulness, and long-term adherence support are essential to sustain viral suppression and prevent treatment failure in Tanzania.

不坚持抗逆转录病毒疗法仍然是实现病毒抑制和艾滋病毒流行病控制的主要障碍,特别是在撒哈拉以南非洲。尽管坦桑尼亚的抗逆转录病毒治疗覆盖率很高,但仍有相当大比例的艾滋病毒感染者未能达到最佳依从性,从而导致耐药性、治疗失败和发病率增加。本研究确定了艾滋病毒感染者中抗逆转录病毒治疗不依从性的患病率和相关因素。在Mwananyamala医院接受抗逆转录病毒治疗的309名艾滋病毒感染者中进行了一项横断面研究。参与者通过简单随机抽样的方式选择。采用结构化问卷调查和病历回顾收集数据,并使用SPSS 26版进行分析。描述性统计确定患病率,而双变量和多变量逻辑回归确定相关因素。优势比(ORs)、95%置信区间(CIs)和p值5年)也与不依从性显著相关(AOR = 1.75, 95% CI: 0.97,3.15, p = 0.041)。健忘是另一个决定因素(AOR = 1.28, 95% CI: 0.36,2.87, p = 0.017)。其他因素如耻辱感、社会支持和酒精使用与不依从性没有显著关联。Mwananyamala医院超过三分之一的艾滋病毒感染者没有坚持抗逆转录病毒治疗。在坦桑尼亚,针对治疗疲劳、健忘和长期依从性支持的有针对性的干预措施对于维持病毒抑制和防止治疗失败至关重要。
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引用次数: 0
Mapping Adolescent Suicidal and Non-Suicidal Self-Injurious Behaviours Across Eastern Australia. 绘制青少年自杀和非自杀自伤行为在澳大利亚东部。
IF 2.2 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-11-19 DOI: 10.1007/s10900-025-01523-0
Ryan Baldwin, Glenn Melvin, Michael McGrath, Ziad Nehme, Harry M X Lai, Matthew Green, Dan I Lubman, Rowan P Ogeil

In Australia, adolescent suicidal and non-suicidal self-injury (NSSI) behaviours have been steadily increasing over that past two decades. However, existing research on the geographic distribution of these behaviours in Australia largely focuses on adults, suicides, or uses pre-COVID-19 data. This study aimed to map and describe the geographic regions where ambulance attendances for adolescent suicidal and NSSI behaviours are occurring. Data from the National Ambulance Surveillance System were used to analyse three-year averages and per capita rates of ambulance attendances for adolescents (12-17 years) across local government areas in New South Wales (NSW), Victoria, and Tasmania from 2021 to 2023. The three-year annual average of ambulance attendances for adolescent suicidal behaviour and NSSI were 6,504 in NSW (35.94 per 10,000), 4,017 in Victoria (25.61 per 10,000), and 444 in Tasmania (44.86 per 10,000). Nearly 90% of attendances required transport to hospital, and over 50% occurred outside traditional service hours. Results identified that Major Cities and high socioeconomic status (SES) local government areas (LGAs), were significantly less likely to have higher rates of ambulance attendances for adolescent suicidal and NSSI behaviours. This study highlights substantial variability across three eastern states of Australia where adolescent suicidal and NSSI behaviours are occurring, demonstrating the need for accessible after-hours mental health support, and that regional and lower SES LGA's are disproportionately impacted. Given the concerning state of adolescent mental health in Australia, this study highlights the need for targeted, data-informed responses to reduce the current reliance on emergency care.

在澳大利亚,青少年自杀和非自杀自伤(NSSI)行为在过去二十年中稳步增长。然而,关于澳大利亚这些行为的地理分布的现有研究主要集中在成年人、自杀或使用covid -19前的数据。本研究旨在绘制和描述发生青少年自杀和自伤行为的救护车出勤的地理区域。来自国家救护车监测系统的数据用于分析2021年至2023年新南威尔士州、维多利亚州和塔斯马尼亚州地方政府区域青少年(12-17岁)的三年平均值和人均救护车上诊率。在新南威尔士州,青少年自杀行为和自伤的三年平均年救护人数为6,504人(每10,000人中有35.94人),维多利亚州为4,017人(每10,000人中有25.61人),塔斯马尼亚州为444人(每10,000人中有44.86人)。近90%的患者需要被送往医院,超过50%的患者在传统服务时间之外就诊。结果发现,主要城市和高社会经济地位(SES)的地方政府区域(lga)的青少年自杀和自伤行为的救护车出诊率明显较低。这项研究强调了澳大利亚东部三个州的实质性差异,这些州的青少年自杀和自伤行为正在发生,这表明需要获得下班后的心理健康支持,并且区域和低经济地位的LGA受到不成比例的影响。鉴于澳大利亚青少年心理健康状况令人担忧,本研究强调需要有针对性的、有数据依据的应对措施,以减少目前对紧急护理的依赖。
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Journal of Community Health
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