{"title":"The association between heavy metal exposure and obesity: A systematic review and meta-analysis","authors":"Moein Zangiabadian, Amir Ghaffari Jolfayi, Seyed Aria Nejadghaderi, Ladan Amirkhosravi, Mojgan Sanjari","doi":"10.1007/s40200-023-01307-0","DOIUrl":"https://doi.org/10.1007/s40200-023-01307-0","url":null,"abstract":"","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"8 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136159391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-27DOI: 10.1007/s40200-023-01330-1
Zhe Liu, Nan Jia, Qianghuizi Zhang, Weiwei Liu
{"title":"Risk prediction models for postpartum glucose intolerance in women with a history of gestational diabetes mellitus: a scoping review","authors":"Zhe Liu, Nan Jia, Qianghuizi Zhang, Weiwei Liu","doi":"10.1007/s40200-023-01330-1","DOIUrl":"https://doi.org/10.1007/s40200-023-01330-1","url":null,"abstract":"","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136261625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-25DOI: 10.1007/s40200-023-01331-0
Sajad Bagheri, Nader Salari, Ahmad Khoshay, Alireza Abdi
{"title":"Assessment of the relationship between self-efficacy criteria and rate of lower limb amputation in diabetic patients; a cross-sectional study","authors":"Sajad Bagheri, Nader Salari, Ahmad Khoshay, Alireza Abdi","doi":"10.1007/s40200-023-01331-0","DOIUrl":"https://doi.org/10.1007/s40200-023-01331-0","url":null,"abstract":"","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"67 1-2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135111695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Elevated triglyceride/high-density lipoprotein-cholesterol ratio as a risk factor for progression to prediabetes: a 5-year retrospective cohort study in Japan","authors":"Masanori Shimodaira, Yu Minemura, Tomohiro Nakayama","doi":"10.1007/s40200-023-01329-8","DOIUrl":"https://doi.org/10.1007/s40200-023-01329-8","url":null,"abstract":"","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"34 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135112612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-25DOI: 10.1007/s40200-023-01332-z
Jakub Jurica, Martin Jozef Péč, Jakub Benko, Tomáš Bolek, Peter Galajda, Marián Mokáň, Matej Samoš
Abstract Objectives The aim of this article is to provide an insight into the role of obesity as a risk factor, and as a potential etiologic agent of atrial fibrillation (AF) and heart failure (HF). Methods A narrative (non-systematic) review article summarizing currently available data regarding the interaction between obesity, AF and HF. Results Obesity is considered a risk factor of AF and chronic HF. Multiple recent studies indicate that obesity is also a potential causal factor in the development of AF and HF, the elucidation of pathological mechanisms of which could help devise new diagnostic and therapeutic modalities for these conditions. The discussion about obesity in relation to HF cannot omit the so-called obesity paradox, which represents a dilemma for clinicians, and it is still a source of irregularities regarding the strategy of weight reduction in obese patients with HF. Recently, the obesity paradox has also been assumed to play a role in the relationship between obesity and thromboembolic complications of AF. Conclusions Obesity is an independent and modifiable risk factor for AF and HF. In addition, there is an increasing volume of experimental and clinical data that suggests an important role of the epicardial adipose tissue in the pathophysiology of AF. However, several issues, such as the issue of optimal pharmacotherapy and weight reduction strategy in obese patients with HF remains still unanswered, and open for future investigation.
{"title":"Obesity as a risk factor in atrial fibrillation and heart failure","authors":"Jakub Jurica, Martin Jozef Péč, Jakub Benko, Tomáš Bolek, Peter Galajda, Marián Mokáň, Matej Samoš","doi":"10.1007/s40200-023-01332-z","DOIUrl":"https://doi.org/10.1007/s40200-023-01332-z","url":null,"abstract":"Abstract Objectives The aim of this article is to provide an insight into the role of obesity as a risk factor, and as a potential etiologic agent of atrial fibrillation (AF) and heart failure (HF). Methods A narrative (non-systematic) review article summarizing currently available data regarding the interaction between obesity, AF and HF. Results Obesity is considered a risk factor of AF and chronic HF. Multiple recent studies indicate that obesity is also a potential causal factor in the development of AF and HF, the elucidation of pathological mechanisms of which could help devise new diagnostic and therapeutic modalities for these conditions. The discussion about obesity in relation to HF cannot omit the so-called obesity paradox, which represents a dilemma for clinicians, and it is still a source of irregularities regarding the strategy of weight reduction in obese patients with HF. Recently, the obesity paradox has also been assumed to play a role in the relationship between obesity and thromboembolic complications of AF. Conclusions Obesity is an independent and modifiable risk factor for AF and HF. In addition, there is an increasing volume of experimental and clinical data that suggests an important role of the epicardial adipose tissue in the pathophysiology of AF. However, several issues, such as the issue of optimal pharmacotherapy and weight reduction strategy in obese patients with HF remains still unanswered, and open for future investigation.","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135113590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-25DOI: 10.1007/s40200-023-01316-z
Marie Auzanneau, Dorothee M. Kieninger, Katharina Laubner, Christian Renner, Joaquina Mirza, Gerhard Däublin, Kirsten Praedicow, Holger Haberland, Claudia Steigleder-Schweiger, Bettina Gohlke, Angela Galler, Reinhard W. Holl
Abstract Purpose To compare the changes in body weight and glycemic control before and during the COVID-19 pandemic in people with type 1 diabetes (T1D). Methods In 47,065 individuals with T1D from the German Diabetes Prospective Follow-up Registry (DPV), we compared the adjusted mean changes in BMI-Z-scores and HbA1c as well as the distribution of individual changes between four periods from March 2018 to February 2022, by sex and age group (4- < 11, 11- < 16, 16–50 years). Results At population level, the only significant pandemic effects were a slight increase in BMI Z-score in prepubertal children (girls: + 0.03 in the first COVID year vs. before, P < 0.01; boys: + 0.04, P < 0.01) as well as a stabilization of HbA1c in all subgroups or even improvement in women (− 0.08%, P < 0.01). At individual level, however, heterogeneity increased significantly (p < 0.01), especially in children. More prepubertal children gained weight (girls: 45% vs. 35% before COVID; boys: 39% vs. 33%). More pubertal girls lost weight (30% vs. 21%) and fewer gained weight (43% vs. 54%). More children had a decreasing HbA1c (prepubertal group: 29% vs. 22%; pubertal girls: 33% vs. 28%; pubertal boys: 32% vs. 25%) and fewer had increasing values. More women had stable HbA1c and fewer had increasing values (30% vs. 37%). In men, no significant changes were observed. Conclusion This real-world analysis shows no detrimental consequences of the two first COVID years on weight and HbA1c in T1D on average, but reveals, beyond the mean trends, a greater variability at the individual level.
目的比较新冠肺炎大流行前后1型糖尿病(T1D)患者体重和血糖控制的变化。方法:在德国糖尿病前瞻性随访登记处(DPV)的47,065例T1D患者中，我们比较了2018年3月至2022年2月四个时期(4- <11, 11- <16、16 - 50岁)。结果在人群水平上，唯一显著的大流行影响是青春期前儿童BMI z评分略有升高(女孩在第一个COVID年与前相比:+ 0.03,P <0.01;男生:+ 0.04,P <0.01)，所有亚组的HbA1c稳定，甚至在女性中有所改善(- 0.08%，P <0.01)。然而，在个体水平上，异质性显著增加(p <0.01)，尤其是儿童。更多的青春期前儿童体重增加(女孩:45% vs. COVID前的35%;男孩:39%对33%)。更多的青春期女孩体重减轻(30%对21%)，而更少的女孩体重增加(43%对54%)。更多的儿童HbA1c下降(青春期前组:29% vs 22%;青春期女孩:33% vs. 28%;青春期男孩:32% vs. 25%)和更少的男孩有增加值。HbA1c稳定的女性较多，升高的女性较少(30% vs. 37%)。在男性中，没有观察到明显的变化。这项现实世界的分析显示，前两年的平均体重和糖化血红蛋白对T1D患者没有不利影响，但除了平均趋势外，个体水平上的差异更大。
{"title":"Comparison of BMI and HbA1c changes before and during the COVID-19 pandemic in type 1 diabetes: a longitudinal population-based study","authors":"Marie Auzanneau, Dorothee M. Kieninger, Katharina Laubner, Christian Renner, Joaquina Mirza, Gerhard Däublin, Kirsten Praedicow, Holger Haberland, Claudia Steigleder-Schweiger, Bettina Gohlke, Angela Galler, Reinhard W. Holl","doi":"10.1007/s40200-023-01316-z","DOIUrl":"https://doi.org/10.1007/s40200-023-01316-z","url":null,"abstract":"Abstract Purpose To compare the changes in body weight and glycemic control before and during the COVID-19 pandemic in people with type 1 diabetes (T1D). Methods In 47,065 individuals with T1D from the German Diabetes Prospective Follow-up Registry (DPV), we compared the adjusted mean changes in BMI-Z-scores and HbA1c as well as the distribution of individual changes between four periods from March 2018 to February 2022, by sex and age group (4- < 11, 11- < 16, 16–50 years). Results At population level, the only significant pandemic effects were a slight increase in BMI Z-score in prepubertal children (girls: + 0.03 in the first COVID year vs. before, P < 0.01; boys: + 0.04, P < 0.01) as well as a stabilization of HbA1c in all subgroups or even improvement in women (− 0.08%, P < 0.01). At individual level, however, heterogeneity increased significantly (p < 0.01), especially in children. More prepubertal children gained weight (girls: 45% vs. 35% before COVID; boys: 39% vs. 33%). More pubertal girls lost weight (30% vs. 21%) and fewer gained weight (43% vs. 54%). More children had a decreasing HbA1c (prepubertal group: 29% vs. 22%; pubertal girls: 33% vs. 28%; pubertal boys: 32% vs. 25%) and fewer had increasing values. More women had stable HbA1c and fewer had increasing values (30% vs. 37%). In men, no significant changes were observed. Conclusion This real-world analysis shows no detrimental consequences of the two first COVID years on weight and HbA1c in T1D on average, but reveals, beyond the mean trends, a greater variability at the individual level.","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"62 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135111924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of clustering of non-communicable disease risk factors in a highly urbanized district of India: findings of a cross-sectional survey in Puducherry","authors":"Parthibane Sivanantham, Jaya Prakash Sahoo, Subitha Lakshminarayanan, Zachariah Bobby, Jeyanthi Anandraj, Sitanshu Sekhar Kar","doi":"10.1007/s40200-023-01318-x","DOIUrl":"https://doi.org/10.1007/s40200-023-01318-x","url":null,"abstract":"","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"25 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135216021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-25DOI: 10.1007/s40200-023-01290-6
Annalena Dunkel, Katja von Storch, Martin Hochheim, Susanne Zank, M. Cristina Polidori, Christiane Woopen
Abstract Purpose Diabetes is considered one of the fastest growing diseases worldwide. Especially in the treatment of type 2 diabetes, lifestyle interventions have proven to be effective. However, long-term studies in real-world contexts are rare, which is why further research is needed. The aim of the present study is to investigate whether effects achieved in the context of a long-term lifestyle intervention can be sustained by patients in the long term. Methods In a two-arm randomized trial we compared diabetes care as usual to a lifestyle intervention combining telemedically support and individual needs-based telephone coaching. The study included 151 patients with type 2 diabetes randomized to either the intervention or control group. Intervention Group (IG; N = 86, 80.2% male, mean age: 59.7) received telemedical devices and telephone coaching over a period of 12 months, Control Group (CG; N = 65, 83.1% male, mean age: 58,8) received care as usual. The primary outcome was chance in Hb A1c . A follow-up survey was conducted after 24 months. Results The intervention group showed significantly better HbA1c- values compared to the control group at both 12 and 24 months (12 M: − 0.52 (-0.73; − 0.32), p < .000; 24 M: − 0.38 (-0.61; − 0.15), p = .001). The strongest change was seen in the first three months, with the best value obtained at 6 months and stable thereafter. Conclusion Combined telephone coaching with telemedicine support could lead to better long-term glycemic control in people with type 2 diabetes. In the future, more long-term studies should be conducted in real-world settings and lifestyle interventions should be offered more widely.
{"title":"Long-term effects of a telemedically-assisted lifestyle intervention on glycemic control in patients with type 2 diabetes – A two-armed randomised controlled trial in Germany","authors":"Annalena Dunkel, Katja von Storch, Martin Hochheim, Susanne Zank, M. Cristina Polidori, Christiane Woopen","doi":"10.1007/s40200-023-01290-6","DOIUrl":"https://doi.org/10.1007/s40200-023-01290-6","url":null,"abstract":"Abstract Purpose Diabetes is considered one of the fastest growing diseases worldwide. Especially in the treatment of type 2 diabetes, lifestyle interventions have proven to be effective. However, long-term studies in real-world contexts are rare, which is why further research is needed. The aim of the present study is to investigate whether effects achieved in the context of a long-term lifestyle intervention can be sustained by patients in the long term. Methods In a two-arm randomized trial we compared diabetes care as usual to a lifestyle intervention combining telemedically support and individual needs-based telephone coaching. The study included 151 patients with type 2 diabetes randomized to either the intervention or control group. Intervention Group (IG; N = 86, 80.2% male, mean age: 59.7) received telemedical devices and telephone coaching over a period of 12 months, Control Group (CG; N = 65, 83.1% male, mean age: 58,8) received care as usual. The primary outcome was chance in Hb A1c . A follow-up survey was conducted after 24 months. Results The intervention group showed significantly better HbA1c- values compared to the control group at both 12 and 24 months (12 M: − 0.52 (-0.73; − 0.32), p < .000; 24 M: − 0.38 (-0.61; − 0.15), p = .001). The strongest change was seen in the first three months, with the best value obtained at 6 months and stable thereafter. Conclusion Combined telephone coaching with telemedicine support could lead to better long-term glycemic control in people with type 2 diabetes. In the future, more long-term studies should be conducted in real-world settings and lifestyle interventions should be offered more widely.","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"2 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134973192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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