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Endometriosis on TikTok: Evaluating social media misinformation and the role of healthcare professionals TikTok 上的子宫内膜异位症:评估社交媒体上的错误信息和医疗保健专业人员的作用
IF 0.5 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2024-01-09 DOI: 10.1177/22840265231220089
Sarah Isaac, Nicole Acero, Kateryna Kolesnikova, Emily Howell
TikTok is often the first source teens and young adult patients turn to for medical information, a short-form social media video application known to promote videos with inaccurate information. The primary goal of this study was to characterize popular endometriosis misinformation found on TikTok, with the secondary goal of describing attitudes surrounding endometriosis on TikTok so that physicians can be knowledgeable about the content available on the internet, and be prepared when patients talk about endometriosis misinformation. The top 100 videos under the three most popular endometriosis search terms were assessed for misinformation in four categories: incorrect causes, incorrect symptoms, incorrect treatment, and other incorrect information. Non-English, inaudible, duplicated, or irrelevant videos were excluded from analysis. Videos were analyzed until 100 valid videos were identified in each search term. Metadata was collected, including whether the video was created by a physician or non-physician and attitudes toward endometriosis. Chi squares, Fisher’s Exact Tests, and Mann–Whitney U tests were performed as appropriate. Of total, 298 videos met the eligibility criteria for review. Fifty videos were created by individual physicians and 248 were created by non-physicians. Overall, out of 298 videos, 69 videos (23%) had incorrect or misleading information about causes, treatment, symptoms, or information about endometriosis. Only 1% of the analyzed videos discussed medication management other than COCPs. Nonphysician sources were associated with negative attitudes ( p < 0.003). Nonphysician videos were more likely to contain misinformation in at least one category, compared to physician videos ( p < 0.0008). Despite the greater volume of non-physician videos, those created by physicians were more likely to be shared. Misinformation from non-physician sources was associated with positive/neutral attitudes toward endometriosis and treatment ( p < 0.00002). This study reveals that TikTok hosts a high volume of endometriosis misinformation, especially about endometrosis treatments. Popular TikTok misinformation tends not to reflect traditional misconceptions, but rather modern misinformation trends of holistic health and “wellness.” Physicians should be prepared to have respectful discussions about endometriosis treatments found on TikTok without invalidating the emotions that led patients to seek information on the internet.
TikTok 通常是青少年和年轻成年患者获取医疗信息的第一渠道,众所周知,这种短视频社交媒体应用会推广含有不准确信息的视频。本研究的主要目的是描述 TikTok 上流行的子宫内膜异位症错误信息的特征,其次是描述 TikTok 上围绕子宫内膜异位症的态度,以便医生了解互联网上的内容,并在患者谈论子宫内膜异位症错误信息时有所准备。我们对三个最热门的子宫内膜异位症搜索词下排名前 100 的视频进行了错误信息评估,共分为四类:错误原因、错误症状、错误治疗和其他错误信息。非英语、听不清、重复或无关的视频不在分析之列。对视频进行分析,直到在每个搜索词中找到 100 个有效视频为止。收集的元数据包括视频是由医生制作的还是非医生制作的,以及人们对子宫内膜异位症的态度。根据情况进行卡方检验、费雪精确检验和曼-惠特尼 U 检验。共有 298 个视频符合审查资格标准。其中 50 个视频由医生个人制作,248 个由非医生制作。总体而言,在 298 个视频中,有 69 个视频(23%)在病因、治疗、症状或子宫内膜异位症相关信息方面存在错误或误导性信息。在分析的视频中,只有 1%的视频讨论了 COCPs 以外的药物治疗。非医生来源与负面态度相关(P < 0.003)。与医生视频相比,非医生视频更有可能包含至少一个类别的错误信息(p < 0.0008)。尽管非医生视频的数量更大,但医生制作的视频更有可能被分享。非医生来源的错误信息与人们对子宫内膜异位症和治疗的积极/中立态度有关(P < 0.00002)。这项研究表明,TikTok 上有大量子宫内膜异位症的错误信息,尤其是关于子宫内膜异位症治疗的信息。TikTok 上流行的错误信息往往反映的不是传统的错误观念,而是现代整体健康和 "保健 "的错误信息趋势。医生应做好准备,就 TikTok 上发现的子宫内膜异位症治疗方法进行相互尊重的讨论,而不要否定导致患者在互联网上寻求信息的情绪。
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引用次数: 0
When cystoscopy catches what laparoscopy misses: The role of cystoscopy in evaluation of bladder endometriosis 膀胱镜检查能发现腹腔镜检查所遗漏的问题:膀胱镜在评估膀胱子宫内膜异位症中的作用
IF 0.5 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2024-01-09 DOI: 10.1177/22840265231220731
G. Ranieri, Johnny Yi, M. Whitney, Megan Wasson
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引用次数: 0
Comprehensive management of umbilical endometriosis using a unique laparoscopic entry portal (Darwish point) and postoperative Dienogest 利用独特的腹腔镜入口(达尔维什点)和术后地诺孕酮综合治疗脐部子宫内膜异位症
IF 0.5 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2023-12-12 DOI: 10.1177/22840265231217355
Atef Darwish, D. Darwish, Mohamed Fathi, Hoda Elmahdi
Umbilical endometriosis, although relatively rare, has been described with plenty of case reports and case series available in the literature. Surgical excision has been the preferred mode of treatment, with or without excision of the umbilicus. Few cases described laparoscopically assisted excision but lacked descriptions of a safe alternative non-umbilical laparoscopy entry portal, management of possible concomitant intraperitoneal lesions, and aesthetic umbilicus repair. The aim of this work is to describe a modified technique of laparoscopically assisted excision of umbilical endometriosis and treat concomitant intraperitoneal lesions via a new laparoscopic entry portal with aesthetic preservation of the umbilicus. Successful complete excision of the mass with aesthetic preservation of the umbilicus followed by 3 months of Dienogest therapy resulted in complete resolution of the mass. It is concluded that utilizing “Darwish point” for abdominal access to excise umbilical endometriosis and treat concomitant intraabdominal lesions, offers smart abdominal access with aesthetic umbilicus repair. Moreover, postoperative hormonal treatment (Dienogest) is helpful to ensure a better cure.
脐部子宫内膜异位症虽然相对罕见,但已有大量病例报告和系列病例见诸文献。手术切除一直是首选的治疗方式,无论是否切除脐部。极少数病例描述了腹腔镜辅助切除术,但缺乏对其他安全的非脐部腹腔镜入路入口、处理可能并发的腹膜内病变以及脐部美学修复的描述。这项研究的目的是描述一种改良的腹腔镜辅助切除脐部子宫内膜异位症的技术,并通过新的腹腔镜入口治疗并发的腹膜内病变,同时保留脐部美观。在保留脐部美观的前提下,成功地完全切除了肿块,随后进行了为期 3 个月的地诺孕酮治疗,结果肿块完全消退。结论是,利用 "达维什点 "开腹切除脐部子宫内膜异位症并治疗腹腔内并发病变,是一种既能开腹又能修复脐部美观的方法。此外,术后激素治疗(地诺孕酮)有助于确保更好的治愈效果。
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引用次数: 0
Chronic pelvic pain: An underrecognised perioperative consideration 慢性盆腔疼痛:未被充分认识的围手术期考虑因素
IF 0.5 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2023-12-04 DOI: 10.1177/22840265231214909
Antoinette Lam, Ruyi Zhang, Adrienne Oxenham, B. Stretton, Nidhi Aujayeb, Sam West, Tim Trewen, Stephen Bacchi, J. Kovoor, Aashray K. Gupta
Chronic pelvic pain (CPP) is a prevalent disorder amongst women. The physiology of CPP is attributed to various neurophysiological mechanisms and endometriosis, adenomyosis, chronic infection and functional disorders such as irritable bowel syndrome or interstitial cystitis are all diseases which fall under the umbrella term of CPP. CPP and its associated multitude of causes can affect perioperative care through several mechanisms. Patients with CPP may be more likely to experience significant pain in the perioperative setting and preoperative pain can be a predictor of post-operative pain. Thus, optimisation of CPP prior to the perioperative period is an important consideration. Currently limited and conflicting evidence exists regarding the peri-operative pharmacological analgesia. The various aetiologies of CPP and patient medical history result in the inability to generalise one analgesic regime. Areas of further research includes neuromodulation techniques, genomic and proteomic biomarker studies and the applicability of artificial intelligence.
慢性盆腔疼痛(CPP)是一种常见的女性疾病。CPP的生理机制可归因于多种神经生理机制,子宫内膜异位症、子宫腺肌病、慢性感染以及肠易激综合征或间质性膀胱炎等功能性疾病都属于CPP的总称。CPP及其相关的多种原因可通过多种机制影响围手术期护理。CPP患者在围手术期可能更容易经历明显的疼痛,术前疼痛可以预测术后疼痛。因此,围手术期前CPP的优化是一个重要的考虑因素。目前关于围手术期药物镇痛的证据有限且相互矛盾。CPP的各种病因和患者病史导致无法推广一种镇痛方案。进一步的研究领域包括神经调节技术、基因组学和蛋白质组学生物标志物研究以及人工智能的适用性。
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引用次数: 0
The Holy Grail of endometriosis biomarkers in the diagnostic process – How much would it be worth and what does it look like? 诊断过程中子宫内膜异位症生物标志物的圣杯——它值多少钱?它看起来像什么?
Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2023-11-08 DOI: 10.1177/22840265231210903
Joanna Kacperczyk-Bartnik, Natalia Żeber-Lubecka, Stepan Feduniw, Paweł Bartnik, Marta Włodarczyk, Monika Abramiuk, Michał Ciebiera
Previously, the gold standard for the diagnosis of endometriosis involved the performance of laparoscopic surgery, which allows the visualization and histological examination of the endometrial tissue. According to the latest guidelines published by the European Society of Human Reproduction and Embryology (ESHRE) in 2022, surgery is recommended only in patients with diagnostic difficulties associated with the use of non-invasive methods or in case of inappropriate or unsuccessful empirical treatment. At the same time, it is not recommended to use the measurement of biomarkers in the endometrial tissue, blood, menstrual or uterine fluids to diagnose endometriosis as the ESHRE guideline development group indicated the need of larger, multi-center prospective studies on this matter. The aim of this narrative review is to present advances in knowledge on non-invasive endometriosis diagnostic opportunities with emphasis on proteomics, the use of endometrial aspiration biopsy, iron metabolism, vitamin D-binding protein, extracellular matrix signaling pathways, epithelial−mesenchymal transformation, and other molecular pathways, together with a critical analysis of studies cited in the recent ESHRE guidelines.
以前,诊断子宫内膜异位症的金标准涉及腹腔镜手术的表现,这允许子宫内膜组织的可视化和组织学检查。根据欧洲人类生殖与胚胎学会(ESHRE)于2022年发布的最新指南,只有在使用非侵入性方法或不适当或不成功的经验治疗导致诊断困难的患者中,才推荐手术。同时,不建议使用子宫内膜组织、血液、月经或子宫液中的生物标志物来诊断子宫内膜异位症,因为ESHRE指南制定小组指出需要对此问题进行更大规模、多中心的前瞻性研究。这篇叙述性综述的目的是介绍非侵入性子宫内膜异位症诊断机会的知识进展,重点是蛋白质组学、子宫内膜穿刺活检的使用、铁代谢、维生素d结合蛋白、细胞外基质信号通路、上皮-间充质转化和其他分子途径,以及最近ESHRE指南中引用的研究的关键分析。
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引用次数: 0
Fertility preservation in patients with endometriosis: Realistic approach or Future fantasy? 子宫内膜异位症患者的生育能力保存:现实的方法还是未来的幻想?
Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2023-11-08 DOI: 10.1177/22840265231209368
Orestis Tsonis, Fani Gkrozou, Minas Paschopoulos, Suruchi Pandey, Julia Kopeika
Fertility preservation techniques, such as cryopreservation of ovarian tissue, embryos, and oocytes, offer hope for future reproduction to individuals facing conditions like cancer or severe haematologic disorders. While the scientific evidence supporting fertility preservation is limited, it shows promise, and there is a growing trend among fertility experts to extend its application to patients with benign conditions that can cause fertility issues, such as endometriosis. Some forms of endometriosis may have a negative impact on fertility, affecting the ovarian reserve, oocyte quality, and the tubo-ovarian interface. Evaluating fertility preservation in endometriosis patients reveals several key considerations. The diverse nature of endometriosis calls for tailored approaches and distinguishing between the disease and treatment effects on ovarian reserve is crucial. Fertility preservation in endometriosis is complex, demanding consideration of disease variability, treatment effects, accurate assessment, and a clear distinction between ovarian reserve and conception ability. A personalised approach is essential for optimal outcomes in this field.
生育保存技术,如卵巢组织、胚胎和卵母细胞的冷冻保存,为面临癌症或严重血液病等疾病的个体提供了未来生殖的希望。虽然支持保留生育能力的科学证据有限,但它显示出了希望,生育专家越来越倾向于将其应用于可能导致生育问题的良性疾病,如子宫内膜异位症。某些形式的子宫内膜异位症可能对生育能力产生负面影响,影响卵巢储备、卵母细胞质量和输卵管-卵巢界面。评估子宫内膜异位症患者的生育能力保存揭示了几个关键因素。子宫内膜异位症的多样性需要量身定制的方法,区分疾病和治疗对卵巢储备的影响至关重要。子宫内膜异位症的生育能力保存是复杂的,需要考虑疾病的可变性、治疗效果、准确的评估以及卵巢储备和受孕能力的明确区分。个性化的方法对于该领域的最佳结果至关重要。
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引用次数: 0
Pelvic floor awareness in women with fibromyalgia: A controlled cross-sectional study 纤维肌痛女性的盆底意识:一项对照横断面研究
Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2023-11-02 DOI: 10.1177/22840265231206872
Yasemin Yumusakhuylu, Hanife Caglar Yagci, Betül Ceyda Senyurt, Afitap Icagasioglu, Özge Pasin, Belgin Erhan
Objective: Fibromyalgia syndrome (FMS), is a painful syndrome of the musculoskeletal system with associating somatic symptoms which may include PF dysfunction (PFD). We aimed to investigate the patients’ awareness of pelvic floor (PF), the frequency, impact and severity of PFD in FMS and to investigate the effect of psychological state on PFD. Methods: Women with FMS and healthy controls enrolled to the study. Demographic data, urinary symptoms and questions regarding PF awareness asked. Fibromyalgia Impact Questionnaire, Beck Depression Questionnaire and Beck Anxiety Questionnaire were filled. SPSS 26 used for statistical analysis. Results: A total of 48 FMS and 48 healthy controls, with a mean age of 44 years were enrolled. The rate of UI in FMS group was significantly higher than the control group ( p < 0.001). The frequency of urinary incontinence (UI) was found 60% in FMS patients, and 25% in the control group. UI duration was significantly longer in the FMS group ( p = 0.013). There was a relation between the duration of UI and anxiety scores. As the duration of UI increases, the anxiety score also increases significantly ( r = 0.318; p = 0.043). The majority of the subjects, 25 (86.2%) patients from the FMS group and 11 (91.7%) patients from the control group, have not consulted any physician about UI complaints, therefore did not receive any treatment. Conclusion: PF awareness is quite low in the general population and in FMS. Studies should be carried out to inform the society about PFD and increase their awareness of the PF, and social responsibility projects should be prepared.
目的:纤维肌痛综合征(FMS)是一种伴有相关躯体症状的肌肉骨骼系统疼痛综合征,其中可能包括PF功能障碍(PFD)。我们旨在探讨FMS患者对盆底(PF)的认知、PFD的发生频率、影响程度和严重程度,并探讨心理状态对PFD的影响。方法:FMS女性和健康对照者加入研究。询问了人口统计数据、泌尿系统症状和有关PF意识的问题。分别填写纤维肌痛影响问卷、Beck抑郁问卷和Beck焦虑问卷。使用SPSS 26进行统计分析。结果:共纳入48例FMS患者和48例健康对照,平均年龄44岁。FMS组患者尿失禁率显著高于对照组(p <0.001)。FMS患者尿失禁发生率为60%,对照组为25%。FMS组患者UI持续时间明显延长(p = 0.013)。尿失禁持续时间与焦虑得分之间存在相关性。焦虑得分也随着UI持续时间的增加而显著增加(r = 0.318;P = 0.043)。大多数受试者,FMS组25例(86.2%)患者和对照组11例(91.7%)患者未因尿失禁投诉咨询任何医生,因此未接受任何治疗。结论:在一般人群和FMS中,PF的认知度很低。应该开展研究,让社会了解PFD,提高他们对PFD的认识,并准备社会责任项目。
{"title":"Pelvic floor awareness in women with fibromyalgia: A controlled cross-sectional study","authors":"Yasemin Yumusakhuylu, Hanife Caglar Yagci, Betül Ceyda Senyurt, Afitap Icagasioglu, Özge Pasin, Belgin Erhan","doi":"10.1177/22840265231206872","DOIUrl":"https://doi.org/10.1177/22840265231206872","url":null,"abstract":"Objective: Fibromyalgia syndrome (FMS), is a painful syndrome of the musculoskeletal system with associating somatic symptoms which may include PF dysfunction (PFD). We aimed to investigate the patients’ awareness of pelvic floor (PF), the frequency, impact and severity of PFD in FMS and to investigate the effect of psychological state on PFD. Methods: Women with FMS and healthy controls enrolled to the study. Demographic data, urinary symptoms and questions regarding PF awareness asked. Fibromyalgia Impact Questionnaire, Beck Depression Questionnaire and Beck Anxiety Questionnaire were filled. SPSS 26 used for statistical analysis. Results: A total of 48 FMS and 48 healthy controls, with a mean age of 44 years were enrolled. The rate of UI in FMS group was significantly higher than the control group ( p < 0.001). The frequency of urinary incontinence (UI) was found 60% in FMS patients, and 25% in the control group. UI duration was significantly longer in the FMS group ( p = 0.013). There was a relation between the duration of UI and anxiety scores. As the duration of UI increases, the anxiety score also increases significantly ( r = 0.318; p = 0.043). The majority of the subjects, 25 (86.2%) patients from the FMS group and 11 (91.7%) patients from the control group, have not consulted any physician about UI complaints, therefore did not receive any treatment. Conclusion: PF awareness is quite low in the general population and in FMS. Studies should be carried out to inform the society about PFD and increase their awareness of the PF, and social responsibility projects should be prepared.","PeriodicalId":15725,"journal":{"name":"Journal of endometriosis and pelvic pain disorders","volume":"25 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135934857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Catamenial pneumothorax: A population-based study 肠膜性气胸:一项基于人群的研究
Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2023-10-30 DOI: 10.1177/22840265231207949
Yaron Gil, Jacques Balayla, Togas Tulandi, Perrine Capmas
Study objective: To characterize the incidence, clinical features, and demographic characteristics of women with catamenial pneumothorax with the use of a large national database in the United States. Design: Retrospective case control study of the Healthcare Cost and Utilization Project, Nationwide Inpatient Sample (HCUP-NIS) database between 2004 and 2014. Setting: Not applicable. Patients: Women, aged 18–50 years, who were diagnosed with a pneumothorax between 2004 and 2014. Intervention: Not applicable. Measurements: The cohort was constructed using the appropriate ICD-9 codes utilizing HCUP-NIS, checking for women with spontaneous and catamenial pneumothorax . Main results: Of a total 6234 women with spontaneous pneumothorax, 80 women (1.3%) had a diagnosis of catamenial pneumothorax. Women with catamenial pneumothorax were more likely to be black, have private insurance and be treated in an urban hospital. In addition, fewer patients in this group reported a history of tobacco consumption. Patients in the study group were more likely to have concomitant pelvic endometriosis, dysmenorrhea, and infertility. Compared to women with non-catamenial pneumothorax, those with catamenial pneumothorax were more frequently treated with thoracic drainage and underwent pleural and diaphragm biopsies. Conclusion: Catamenial pneumothorax is a rare entity with a distinct clinical profile. This condition is associated with pelvic endometriosis, has a predilection for surgical intervention and is associated with lower rates of smoking.
研究目的:通过使用美国大型国家数据库来描述女性双侧气胸的发病率、临床特征和人口统计学特征。设计:对2004 - 2014年全国住院病人样本(HCUP-NIS)数据库的医疗成本与利用项目进行回顾性病例对照研究。设置:不适用。患者:年龄在18-50岁之间,在2004年至2014年间被诊断为气胸的女性。干预:不适用。测量方法:采用适当的ICD-9编码,利用HCUP-NIS构建队列,检查自发性和偶发性气胸妇女。主要结果:在6234例自发性气胸患者中,80例(1.3%)诊断为肠膜性气胸。患有先天性气胸的女性更可能是黑人,拥有私人保险,在城市医院接受治疗。此外,该组中报告有烟草消费史的患者较少。研究组的患者更有可能伴有盆腔子宫内膜异位症、痛经和不孕症。与非肠膜性气胸患者相比,肠膜性气胸患者更常接受胸腔引流和胸膜及膈膜活检。结论:系膜性气胸是一种罕见的疾病,临床表现独特。这种情况与盆腔子宫内膜异位症有关,倾向于手术干预,并与较低的吸烟率有关。
{"title":"Catamenial pneumothorax: A population-based study","authors":"Yaron Gil, Jacques Balayla, Togas Tulandi, Perrine Capmas","doi":"10.1177/22840265231207949","DOIUrl":"https://doi.org/10.1177/22840265231207949","url":null,"abstract":"Study objective: To characterize the incidence, clinical features, and demographic characteristics of women with catamenial pneumothorax with the use of a large national database in the United States. Design: Retrospective case control study of the Healthcare Cost and Utilization Project, Nationwide Inpatient Sample (HCUP-NIS) database between 2004 and 2014. Setting: Not applicable. Patients: Women, aged 18–50 years, who were diagnosed with a pneumothorax between 2004 and 2014. Intervention: Not applicable. Measurements: The cohort was constructed using the appropriate ICD-9 codes utilizing HCUP-NIS, checking for women with spontaneous and catamenial pneumothorax . Main results: Of a total 6234 women with spontaneous pneumothorax, 80 women (1.3%) had a diagnosis of catamenial pneumothorax. Women with catamenial pneumothorax were more likely to be black, have private insurance and be treated in an urban hospital. In addition, fewer patients in this group reported a history of tobacco consumption. Patients in the study group were more likely to have concomitant pelvic endometriosis, dysmenorrhea, and infertility. Compared to women with non-catamenial pneumothorax, those with catamenial pneumothorax were more frequently treated with thoracic drainage and underwent pleural and diaphragm biopsies. Conclusion: Catamenial pneumothorax is a rare entity with a distinct clinical profile. This condition is associated with pelvic endometriosis, has a predilection for surgical intervention and is associated with lower rates of smoking.","PeriodicalId":15725,"journal":{"name":"Journal of endometriosis and pelvic pain disorders","volume":"1983 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136069531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Are positive clinical gains observed following physiotherapy treatment for persistent pelvic pain sustained to 12 months following programme completion? A follow up study 对持续盆腔疼痛进行物理治疗后12个月是否观察到积极的临床获益?一项后续研究
Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2023-10-14 DOI: 10.1177/22840265231204657
Tara Beaumont
Introduction: Persistent pelvic pain is a common and often debilitating health condition, which is associated with significant healthcare costs. A three-treatment arm clinical trial investigating the impact of physiotherapy in the management of persistent pelvic pain demonstrated positive clinical outcomes, as measured at the conclusion of the programmes, in terms of pain score and pain impact. This study aimed to test the sustainability of the clinical gains observed through to 12 months post-programme completion. Methods: Participants who completed the clinical trial ( N = 66) were contacted as they neared the 12 months anniversary of the completion of their treatment programme. Returned data was collated and analysed against data obtained during the trial, allowing comparison pre-treatment, post-treatment and at 12 months following programme completion. Results: There were 24 returned outcome measurement documents, representing a 38% response rate. Of the three treatments arms piloted in the trial, one arm demonstrated further clinical improvement across a range of domains in the 12 months following treatment, while participants in the other two treatment arms returned data suggesting mild clinical decline. However, when comparing pre-treatment baseline data with data obtained at 12 months post treatment, all three treatment cohorts returned positive clinical gains across all measures. This effect was more pronounced in those who maintained three to six monthly contact with the department following treatment programme completion. Discussion: Physiotherapy treatment – either individual sessions, or a series of individual sessions coupled with group education ± group exercise – results in positive clinical gains from baseline assessment that are sustained through to 12 months following treatment programme completion. Universal trial number: U1111-1228-4810 ANZCTR.
导读:持续性骨盆疼痛是一种常见且经常使人衰弱的健康状况,与显著的医疗费用相关。一项研究物理治疗对持续性骨盆疼痛管理影响的三治疗组临床试验显示,在项目结束时,就疼痛评分和疼痛影响而言,临床结果是积极的。本研究旨在测试在项目完成后12个月观察到的临床收益的可持续性。方法:完成临床试验的参与者(N = 66)在接近其治疗方案完成12个月纪念日时进行联系。将返回的数据与试验期间获得的数据进行整理和分析,以便比较治疗前、治疗后和方案完成后12个月的数据。结果:共返回结果测量文件24份,应答率38%。在试验中试点的三个治疗组中,一个治疗组在治疗后的12个月内在一系列领域显示出进一步的临床改善,而另外两个治疗组的参与者返回的数据显示轻度临床衰退。然而,当比较治疗前基线数据与治疗后12个月获得的数据时,所有三个治疗队列在所有测量中都获得了积极的临床收益。这种效果在那些在治疗方案完成后每月与部门保持三到六个联系的人身上更为明显。讨论:物理治疗——无论是单独治疗,还是一系列单独治疗结合团体教育±团体锻炼——从基线评估中获得积极的临床收益,持续到治疗方案完成后的12个月。通用试号:U1111-1228-4810 ANZCTR。
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引用次数: 0
MRI markers of adenomyosis severity associated with worse IVF/ICSI outcomes 子宫腺肌症严重程度的MRI标记与较差的IVF/ICSI结果相关
IF 0.5 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2023-08-28 DOI: 10.1177/22840265231195404
C. Rees, Sehriban Kocyigit, J. Nederend, M. Mischi, H. van Vliet, B. Schoot
The aim of this study was to characterise the severity of adenomyosis on MRI in infertile women, and to assess if MRI characteristics of adenomyosis severity are associated with worse IVF/ICSI pregnancy outcomes versus male infertility controls. This single-centre retrospective study was carried out at Catharina Hospital in Eindhoven, The Netherlands. The MRIs of 124 infertile women undergoing their first, fresh embryo transfer during IVF/ICSI, diagnosed with adenomyosis only ( N = 31), or combined adenomyosis and endometriosis ( N = 93) were assessed. Measurements of MRI adenomyosis features were performed by two independent investigators. IVF/ICSI outcomes (biochemical pregnancy (BP), ongoing pregnancy (OP) and live birth (LB)) of adenomyosis patients were compared to those of 889 male infertility controls. Patients with adenomyosis had significantly worse IVF/ICSI outcomes compared to male infertility controls. When assessing individual MRI parameters, adenomyosis patients with a mean junctional zone (JZ) of >12 mm, a JZ/Myometrium ratio of >40%, presence of myometrial cysts and presence of endometriosis (specifically deep invasive endometriosis(DIE)) showed statistically significantly worse outcomes compared to patients with milder disease. The results of this retrospective study suggest that individual MRI markers for severe adenomyosis (mean JZ > 12 mm, myometrial cysts), especially when combined with (severe) endometriosis, may be associated with fewer pregnancies during IVF/ICSI when compared to male infertility controls. Future prospective studies should investigate the prognostic potential of these markers for prediction of IVF/ICSI success.
本研究的目的是在MRI上描述不孕症女性子宫腺肌症的严重程度,并评估子宫腺肌症严重程度的MRI特征是否与较差的IVF/ICSI妊娠结局与男性不育对照组相关。这项单中心回顾性研究在荷兰埃因霍温的Catharina医院进行。124名在IVF/ICSI期间进行第一次新鲜胚胎移植的不孕症妇女,诊断为子宫腺肌症(N = 31)或子宫腺肌症合并子宫内膜异位症(N = 93)的mri进行评估。MRI子宫腺肌症特征的测量由两名独立调查员进行。将子宫腺肌症例患者的IVF/ICSI结果(生化妊娠(BP)、持续妊娠(OP)和活产(LB))与889例男性不育对照组进行比较。与男性不育对照组相比,子宫腺肌症患者的IVF/ICSI结果明显更差。在评估个体MRI参数时,平均连接区(JZ)为> 12mm, JZ/肌层比率为>40%,存在子宫肌瘤囊肿和存在子宫内膜异位症(特别是深部浸润性子宫内膜异位症(DIE))的子宫腺肌症患者的预后与轻度疾病患者相比具有统计学意义上的显着差异。这项回顾性研究的结果表明,与男性不育对照组相比,严重子宫腺肌症(平均JZ >12mm,子宫肌瘤囊肿)的个体MRI标记物,特别是合并(严重)子宫内膜异位症时,可能与IVF/ICSI期间怀孕较少有关。未来的前瞻性研究应探讨这些标志物在预测IVF/ICSI成功方面的预后潜力。
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引用次数: 0
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Journal of endometriosis and pelvic pain disorders
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