Objective: Decidual cast in other words membranous dysmenorrhea is a rare entity. Hereby, we report the first infected case caused by drospirenon containing contraceptive use and managed successfully by hysteroscopy.
Case presentation: A13 year-old girl started on drospirenon containing contraceptive theraphy since her menarche resulted in menorrhagia and anemia that requires transfusion. On follow up, she developed a partially discharged infected mass revealed to be a decidual cast on pathological review.
Discussion: Membranous dysmenorrhea occurs more frequently in the adolescent and young adult population. All cases in this review were on hormonal theraphy except one occured spontaneously. Cast formation of the immature uterus after menarche is an exaggerated response to dose-independent increased progestin levels.
Conclusion: We conclude that diagnosis of decidual cast/membranous dysmenorrhea should be kept in mind for colicky pain with bleeding of adolescents under hormonal contraceptive therapy and partially discharged cases may be managed successfully by hysteroscopy.
{"title":"Hysteroscopic management of infected and partially discharged desidual cast in an adolescent: A case report and review of the literature in adolescents","authors":"Elcin Telli, Mehmet Surhan Arda","doi":"10.46328/aejog.v5i2.148","DOIUrl":"https://doi.org/10.46328/aejog.v5i2.148","url":null,"abstract":"Objective: Decidual cast in other words membranous dysmenorrhea is a rare entity. Hereby, we report the first infected case caused by drospirenon containing contraceptive use and managed successfully by hysteroscopy.
 Case presentation: A13 year-old girl started on drospirenon containing contraceptive theraphy since her menarche resulted in menorrhagia and anemia that requires transfusion. On follow up, she developed a partially discharged infected mass revealed to be a decidual cast on pathological review.
 Discussion: Membranous dysmenorrhea occurs more frequently in the adolescent and young adult population. All cases in this review were on hormonal theraphy except one occured spontaneously. Cast formation of the immature uterus after menarche is an exaggerated response to dose-independent increased progestin levels.
 Conclusion: We conclude that diagnosis of decidual cast/membranous dysmenorrhea should be kept in mind for colicky pain with bleeding of adolescents under hormonal contraceptive therapy and partially discharged cases may be managed successfully by hysteroscopy.","PeriodicalId":159256,"journal":{"name":"Aegean Journal of Obstetrics and Gynecology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135149596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
giriiş
Oxidative stress (OS) occurs due to overproduction of reactive oxygen radicals (ROS) or weakening of anti-oxidant mechanisms and may harm fertility. Our study aimed to investigate the effects of combined support therapy containing antioxidant agents and vitamin complexes on fertility.
Material method
In this retrospective case-control study, 300 randomly selected infertile men were included. For four months, the effect of daily intake of an antioxidant-multivitamin complex containing astaxhantin (5mg), Coenzyme Q10 (100mg), L-Arginine (250mg), L-Carnitine (250mg), Selenium (100mcg), Zinc (10mg), Folic acid (400mcg), Vitamin E (100mg) and Vitamin C (100mg) on spermiogram parameters was investigated.
Results
Semen hacminde (2.21 ml -3.05 ml; p=.004), sperm konsantrasyonunda (9.60 milyon/ml -14.10 milyon/ml; p=.000), ileri hareketli sperm sayısında (%16.50 -%26.65; p=.000) ), sperm canlılık oranında (%48 - %68; p=.001) beslenme desteği alan hastalarda istatistiksel olarak anlamlı artış bulundu. Ayrıca tedavinin anormal morfolojiye sahip hasta sayısında (Kruger kriterlerine göre normal morfolojiye ulaşamayan hastaların en az %4'ü) anlamlı azalma (%77 - %61; p=.002) sağladığı belirlendi. ).
Çözüm
Astaxhantin, KoQ10, L-arjinin, L-karnitin, selenyum, çinko, E ve C vitaminleri içeren antioksidan-multivitamin içerikli besin takviyelerinin semen hacmi, sperm morfolojisi, canlılık ve motilite üzerinde anlamlı iyileşme sağladığı belirlendi. Bu bağlamda antioksidan-multivitamin kompleksinin erkek kısırlığında destekleyici tedavi için gıda takviyesi olarak kullanılabileceğini öngörüyoruz.
giriiş& # x0D;氧化应激(OS)是由于活性氧自由基(ROS)的过量产生或抗氧化机制的减弱而发生的，并可能损害生育能力。本研究旨在探讨含抗氧化剂和维生素复合物的联合支持疗法对生育能力的影响。材料方法# x0D;在这项回顾性病例对照研究中，随机选择300名不育男性。在四个月的时间里，研究了每天摄入含有虾青素(5mg)、辅酶Q10 (100mg)、l -精氨酸(250mg)、l -肉碱(250mg)、硒(100mcg)、锌(10mg)、叶酸(400mcg)、维生素E (100mg)和维生素C (100mg)的抗氧化剂-复合维生素复合物对精子图参数的影响。结果# x0D;沙克敏精液(2.21 ml -3.05 ml;P = 0.004)，精子konsanasyonunda(960万- 1410万/ml;P = 0.000)，哈雷克特肠杆菌精子sayısında (%16.50 -%26.65;P =.000))，精子canlılık oranında (%48 - %68;P =.001) beslenme desteği Alan hastalarda statistica sel olak anlamlli artış bulundu。Ayrıca tedavinin normal morfolojiye sahip hasta sayısında (Kruger kriterlerine göre normal morfolojiye ula amayan hastaların en az %4'ü) anlamlylazalma (%77 - %61;P =.002) sağladığı belirlendi。强生的# x0D;Cozum& # x0D;虾青素，KoQ10, L-arjinin, L-karnitin，硒，inko, E - ve - C维生素eri eren -复合维生素。但是bağlamda抗钾素-复合维生素kompleksinin erkek kısırlığında destekleyici tedavi i in gıda takviyesi olarak kullanılabileceğini öngörüyoruz。
{"title":"Effect of an antioxidant agent-multivitamin complex food supplement on spermiogram in infertile men","authors":"Pınar Tuğçe Özer, Nursen Atasoy, Adnan Budak, Hatice Öntürk Akyüz","doi":"10.46328/aejog.v5i2.137","DOIUrl":"https://doi.org/10.46328/aejog.v5i2.137","url":null,"abstract":"giriiş
 Oxidative stress (OS) occurs due to overproduction of reactive oxygen radicals (ROS) or weakening of anti-oxidant mechanisms and may harm fertility. Our study aimed to investigate the effects of combined support therapy containing antioxidant agents and vitamin complexes on fertility.
 Material method
 In this retrospective case-control study, 300 randomly selected infertile men were included. For four months, the effect of daily intake of an antioxidant-multivitamin complex containing astaxhantin (5mg), Coenzyme Q10 (100mg), L-Arginine (250mg), L-Carnitine (250mg), Selenium (100mcg), Zinc (10mg), Folic acid (400mcg), Vitamin E (100mg) and Vitamin C (100mg) on spermiogram parameters was investigated.
 Results
 Semen hacminde (2.21 ml -3.05 ml; p=.004), sperm konsantrasyonunda (9.60 milyon/ml -14.10 milyon/ml; p=.000), ileri hareketli sperm sayısında (%16.50 -%26.65; p=.000) ), sperm canlılık oranında (%48 - %68; p=.001) beslenme desteği alan hastalarda istatistiksel olarak anlamlı artış bulundu. Ayrıca tedavinin anormal morfolojiye sahip hasta sayısında (Kruger kriterlerine göre normal morfolojiye ulaşamayan hastaların en az %4'ü) anlamlı azalma (%77 - %61; p=.002) sağladığı belirlendi. ).
 Çözüm
 Astaxhantin, KoQ10, L-arjinin, L-karnitin, selenyum, çinko, E ve C vitaminleri içeren antioksidan-multivitamin içerikli besin takviyelerinin semen hacmi, sperm morfolojisi, canlılık ve motilite üzerinde anlamlı iyileşme sağladığı belirlendi. Bu bağlamda antioksidan-multivitamin kompleksinin erkek kısırlığında destekleyici tedavi için gıda takviyesi olarak kullanılabileceğini öngörüyoruz.","PeriodicalId":159256,"journal":{"name":"Aegean Journal of Obstetrics and Gynecology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135149411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alper Togay, Duygu Tekin, Mehmet Özer, Özden Sıla Kılınç Gönüllü
Objective: The aim of this study was to research the pregnancy outcomes of women with anti-beta2 glycoprotein 1 and anti-cardiolipin antibody positivity and to determine the association with pregnancy morbidity.
Materials and methods: This retrospective study contained pregnant women with anti-beta2 glycoprotein 1 and anti-cardiolipin antibody positivity and a control group without these antibodies. Totally 190 serum samples sent from Obstetrics and Gynecology clinics between January 2019 and January 2023 were analyzed in the medical microbiology laboratory of xx.
Results: In a patient population separated into antibody-positive and antibody-negative groups, the gravida was found to be 3.8±0.1 and 3.5±0.3 respectively (p=0.333). Parity was 1.1±0.1 and 0.8±0.1 (p=0.071), abortion rates were 2.3±0.1 and 2.5±0.2 (p=0.659), and gestational age was 35.7±0.8 and 34±1.5 (p=0.047). Intrauterine fetal death was found to be higher in the antibody-positive group compared to the antibody-negative group (p=0.03). There was no noteworthy distinction noted between the two groups regarding additional pregnancy complications such as intrauterine growth restriction, oligohydramnios, gestational diabetes, and gestational hypertension (respectively p=0.623, 0.074, 0.312, 0.626). However, smoking was significantly higher in the antibody-positive group (p=0.049).
Conclusion: Antiphospholipid syndrome adversely affects pregnancy outcomes. During the initial visit, a thorough patient history should be obtained, and in pregnant women with a history of poor obstetric outcomes or habitual abortions, this syndrome should be considered.
{"title":"The effect of anti-phospholipid syndrome on pregnancy outcomes in patients with habitual abortus","authors":"Alper Togay, Duygu Tekin, Mehmet Özer, Özden Sıla Kılınç Gönüllü","doi":"10.46328/aejog.v5i2.154","DOIUrl":"https://doi.org/10.46328/aejog.v5i2.154","url":null,"abstract":"Objective: The aim of this study was to research the pregnancy outcomes of women with anti-beta2 glycoprotein 1 and anti-cardiolipin antibody positivity and to determine the association with pregnancy morbidity.
 Materials and methods: This retrospective study contained pregnant women with anti-beta2 glycoprotein 1 and anti-cardiolipin antibody positivity and a control group without these antibodies. Totally 190 serum samples sent from Obstetrics and Gynecology clinics between January 2019 and January 2023 were analyzed in the medical microbiology laboratory of xx.
 Results: In a patient population separated into antibody-positive and antibody-negative groups, the gravida was found to be 3.8±0.1 and 3.5±0.3 respectively (p=0.333). Parity was 1.1±0.1 and 0.8±0.1 (p=0.071), abortion rates were 2.3±0.1 and 2.5±0.2 (p=0.659), and gestational age was 35.7±0.8 and 34±1.5 (p=0.047). Intrauterine fetal death was found to be higher in the antibody-positive group compared to the antibody-negative group (p=0.03). There was no noteworthy distinction noted between the two groups regarding additional pregnancy complications such as intrauterine growth restriction, oligohydramnios, gestational diabetes, and gestational hypertension (respectively p=0.623, 0.074, 0.312, 0.626). However, smoking was significantly higher in the antibody-positive group (p=0.049).
 Conclusion: Antiphospholipid syndrome adversely affects pregnancy outcomes. During the initial visit, a thorough patient history should be obtained, and in pregnant women with a history of poor obstetric outcomes or habitual abortions, this syndrome should be considered.","PeriodicalId":159256,"journal":{"name":"Aegean Journal of Obstetrics and Gynecology","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135149413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The Ductus Venosus (DV) connects the umbilical vein to the inferior vena cava. With a portocaval pressure gradient, the well-oxygenated blood in the ductus venosus accelerates towards the left sidewall of the inferior vena cava, directing the blood preferentially towards cephalic and coronary circulation through the foramen ovale (1). DV serves as a shunt, expanding to protect the heart and brain in hypoxic conditions. Ductus Venosus Agenesis (DVA) is a rare congenital abnormality with a prevalence of 0.03-0.07%. The type of DVA, along with any additional anatomical or chromosomal anomalies in fetuses with DVA, significantly affects the postnatal prognosis. Some fetuses with DVA develop normally, while others may experience growth retardation, heart defects, or other complications. In this study, we aimed to evaluate the frequency of associated anomalies in DVA cases, examine the impact of each type of DVA (intrahepatic and extrahepatic venous drainage) on prognosis, and contribute to the literature on this rare disease. Materials and Methods: We conducted a retrospective study of all cases diagnosed prenatally with DVA at a tertiary center between 2016-2019. Our study reviewed obstetric data, associated anomalies, other systemic anomalies, type of DVA, chromosomal or genetic anomalies, and perinatal and postnatal outcomes. Postnatal infants were followed up to the 6th month. Results: We identified 16 cases with ductus venosus agenesis. The type of DVA (intrahepatic-extrahepatic shunt), presence of chromosomal anomalies, accompanying ultrasonographic findings, and perinatal outcomes were recorded. Generally, in 7 out of the 16 cases, the umbilical vein drained into the portal system (44% - intrahepatic), and in 9 cases, it drained into the systemic venous system. Conclusion: DVA is a rare congenital abnormality with potentially significant implications for affected fetuses and infants. Early diagnosis, careful monitoring, and appropriate management strategies are crucial to optimize outcomes for these patients. There's a need for future research to better understand the underlying etiology and pathophysiology of DVA and to develop more effective treatment options for affected individuals.
{"title":"Impact of the type of ductus venosus agenesis and the presence of associated anomalies on prognosis","authors":"Züat Acar, Yusuf Başkıran","doi":"10.46328/aejog.v5i2.152","DOIUrl":"https://doi.org/10.46328/aejog.v5i2.152","url":null,"abstract":"Objective: The Ductus Venosus (DV) connects the umbilical vein to the inferior vena cava. With a portocaval pressure gradient, the well-oxygenated blood in the ductus venosus accelerates towards the left sidewall of the inferior vena cava, directing the blood preferentially towards cephalic and coronary circulation through the foramen ovale (1). DV serves as a shunt, expanding to protect the heart and brain in hypoxic conditions. Ductus Venosus Agenesis (DVA) is a rare congenital abnormality with a prevalence of 0.03-0.07%. The type of DVA, along with any additional anatomical or chromosomal anomalies in fetuses with DVA, significantly affects the postnatal prognosis. Some fetuses with DVA develop normally, while others may experience growth retardation, heart defects, or other complications. In this study, we aimed to evaluate the frequency of associated anomalies in DVA cases, examine the impact of each type of DVA (intrahepatic and extrahepatic venous drainage) on prognosis, and contribute to the literature on this rare disease. Materials and Methods: We conducted a retrospective study of all cases diagnosed prenatally with DVA at a tertiary center between 2016-2019. Our study reviewed obstetric data, associated anomalies, other systemic anomalies, type of DVA, chromosomal or genetic anomalies, and perinatal and postnatal outcomes. Postnatal infants were followed up to the 6th month. Results: We identified 16 cases with ductus venosus agenesis. The type of DVA (intrahepatic-extrahepatic shunt), presence of chromosomal anomalies, accompanying ultrasonographic findings, and perinatal outcomes were recorded. Generally, in 7 out of the 16 cases, the umbilical vein drained into the portal system (44% - intrahepatic), and in 9 cases, it drained into the systemic venous system. Conclusion: DVA is a rare congenital abnormality with potentially significant implications for affected fetuses and infants. Early diagnosis, careful monitoring, and appropriate management strategies are crucial to optimize outcomes for these patients. There's a need for future research to better understand the underlying etiology and pathophysiology of DVA and to develop more effective treatment options for affected individuals.","PeriodicalId":159256,"journal":{"name":"Aegean Journal of Obstetrics and Gynecology","volume":"185 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135149590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alper İleri, İbrahim Karaca, Suna Yıldırım Karaca, Hande İleri, Can Ata, Pınar Tuğçe Özer, Ahmet Demir
Objective: Genital human papillomavirus (HPV) infection is the most common sexually transmitted viral infection worldwide with a prevalence of 10-12% in the female population in the reproductive age; few studies addressed the effect of HPV infection on fertility. It is aimed to investigate the presence of HPV infection in infertile women in the present study.
Materials and methods: In this retrospective cross-sectional study; the outpatient infertility clinic records between July 2020 and January 2023, were evaluated. Infertility examination and evaluation were performed following the guidelines. Infertile female individuals and control group’s HPV results were analyzed.
Results: 234 infertile and 340 non-infertile females were included in the study, HPV positivity was found %11.5 for all infertile women. No significant relationship was found between and HPV (p=0.850).
Conclusion: No significant association was found between female infertility and HPV. Still HPV may play a role in infertility with different genotypes. Further studies should include HPV genotypes.
{"title":"The association between cervical HPV and female fertility","authors":"Alper İleri, İbrahim Karaca, Suna Yıldırım Karaca, Hande İleri, Can Ata, Pınar Tuğçe Özer, Ahmet Demir","doi":"10.46328/aejog.v5i2.158","DOIUrl":"https://doi.org/10.46328/aejog.v5i2.158","url":null,"abstract":"Objective: Genital human papillomavirus (HPV) infection is the most common sexually transmitted viral infection worldwide with a prevalence of 10-12% in the female population in the reproductive age; few studies addressed the effect of HPV infection on fertility. It is aimed to investigate the presence of HPV infection in infertile women in the present study.
 
 Materials and methods: In this retrospective cross-sectional study; the outpatient infertility clinic records between July 2020 and January 2023, were evaluated. Infertility examination and evaluation were performed following the guidelines. Infertile female individuals and control group’s HPV results were analyzed.
 
 Results: 234 infertile and 340 non-infertile females were included in the study, HPV positivity was found %11.5 for all infertile women. No significant relationship was found between and HPV (p=0.850).
 
 Conclusion: No significant association was found between female infertility and HPV. Still HPV may play a role in infertility with different genotypes. Further studies should include HPV genotypes.","PeriodicalId":159256,"journal":{"name":"Aegean Journal of Obstetrics and Gynecology","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135149595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehmet Özer, Pınar Tuğçe Özer, Alper İleri, Barış Sever, Onur Aldemir, Funda Genç, Mücahit Furkan Balcı, Gürsoy Pala
Objective: The management and surgery of placenta previa describe a challenging process that requires experience. It is important to decide on the timing of planned cesarean section in women with placenta previa, taking into account the balance between possible maternal severe bleeding and possible neonatal morbidities.
Material and methods: In the present study, the data of 349 singleton pregnant women with a diagnosis of placenta previa uncomplicated by placenta accreta spectrum were analyzed. Patients who underwent planned (68%, n=236) or emergency cesarean section (32%, n=113) were divided into two groups. In this study, maternal demographic and clinical information, surgical procedures and maternal/neonatal outcomes were studied.
Results: The proportion of patients who underwent uterine compression suture and Bakri balloon was found to be significantly higher in the emergency cesarean section group compared to the planned cesarean deliveries group (p<0.001). The operation time, hospital stay, urinary tract infection rate, decrease in hemoglobin and need for blood transfusion were found to be significantly higher in the emergency cesarean section group compared to the planned cesarean section group (p<0.001, p<0.001, p<0.001, p<0.001, p<0.001, p<0.001, respectively). In addition, a significant association was detected between emergency cesarean section and prematurity, low birth weight, low APGAR score, increased neonatal intensive care unit hospitalization and neonatal mortality.
Conclusion: Cases of placenta previa are at risk of emergency cesarean delivery, which can be complicated by poor maternal and neonatal outcomes. Equipped centers and experienced teams are of great importance in reducing fetomaternal morbidity and mortality caused by placenta previa.
目的:前置胎盘的处理和手术是一个具有挑战性的过程，需要经验。有前置胎盘的妇女在决定计划剖宫产的时机时，考虑到可能的产妇大出血和可能的新生儿发病率之间的平衡是很重要的。材料与方法:对349例经胎盘增生谱诊断为前置胎盘的单胎孕妇资料进行分析。接受计划剖宫产(68%，n=236)或紧急剖宫产(32%，n=113)的患者分为两组。在这项研究中，研究了孕产妇人口统计学和临床信息、手术方式和孕产妇/新生儿结局。
结果:与计划剖宫产组相比，紧急剖宫产组患者行子宫压缩缝合和Bakri球囊术的比例显著高于计划剖宫产组(p<0.001)。急诊剖宫产组的手术时间、住院时间、尿路感染率、血红蛋白下降、输血需要明显高于计划剖宫产组(p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001)。此外，急诊剖宫产与早产、低出生体重、低APGAR评分、新生儿重症监护病房住院率增加和新生儿死亡率显著相关。
结论:前置胎盘患者存在紧急剖宫产的风险，并可并发不良的孕产妇和新生儿结局。设备齐全的中心和经验丰富的团队对于降低前置胎盘引起的母婴发病率和死亡率至关重要。
{"title":"Evaluation of maternal and neonatal outcomes of emergency cesarean deliveries in cases of placenta previa uncomplicated with placenta acreata spectrum","authors":"Mehmet Özer, Pınar Tuğçe Özer, Alper İleri, Barış Sever, Onur Aldemir, Funda Genç, Mücahit Furkan Balcı, Gürsoy Pala","doi":"10.46328/aejog.v5i2.159","DOIUrl":"https://doi.org/10.46328/aejog.v5i2.159","url":null,"abstract":"Objective: The management and surgery of placenta previa describe a challenging process that requires experience. It is important to decide on the timing of planned cesarean section in women with placenta previa, taking into account the balance between possible maternal severe bleeding and possible neonatal morbidities.
 Material and methods: In the present study, the data of 349 singleton pregnant women with a diagnosis of placenta previa uncomplicated by placenta accreta spectrum were analyzed. Patients who underwent planned (68%, n=236) or emergency cesarean section (32%, n=113) were divided into two groups. In this study, maternal demographic and clinical information, surgical procedures and maternal/neonatal outcomes were studied.
 Results: The proportion of patients who underwent uterine compression suture and Bakri balloon was found to be significantly higher in the emergency cesarean section group compared to the planned cesarean deliveries group (p<0.001). The operation time, hospital stay, urinary tract infection rate, decrease in hemoglobin and need for blood transfusion were found to be significantly higher in the emergency cesarean section group compared to the planned cesarean section group (p<0.001, p<0.001, p<0.001, p<0.001, p<0.001, p<0.001, respectively). In addition, a significant association was detected between emergency cesarean section and prematurity, low birth weight, low APGAR score, increased neonatal intensive care unit hospitalization and neonatal mortality.
 Conclusion: Cases of placenta previa are at risk of emergency cesarean delivery, which can be complicated by poor maternal and neonatal outcomes. Equipped centers and experienced teams are of great importance in reducing fetomaternal morbidity and mortality caused by placenta previa.","PeriodicalId":159256,"journal":{"name":"Aegean Journal of Obstetrics and Gynecology","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135149587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To explore the roles of anti-mullerian hormone (AMH) and follicle stimulating hormone (FSH) in predicting clinical pregnancy. Materials and Methods: Forty patients who were decided on IVF/ICSI due to different infertility etiologies were included in the study. The patients were divided into two groups according to their AMH and FSH values as having a good prognosis or a poor prognosis. The clinical pregnancy and miscarriage rates of 33 cycles with good prognosis and 17 cycles with poor prognosis were compared. Results: In the good prognosis group, the FSH value was significantly lower than the poor prognosis group (5.98±1.04 mIU/mL vs. 13.6±3.07 mIU/mL, p<0.01), while the serum AMH level was significantly higher. (3.80±1.32 ng/mL vs 0.54±0.02 ng/mL, p<0.01). The rate of chemical pregnancy in the group with good prognosis was twice as high and significant compared to the group with poor prognosis (12 (36.3%) vs 5 (29.4%), p<0.02). In terms of clinical pregnancy rates, the group with good prognosis showed a higher frequency (33.3% vs. 23.5%, p<0.001), while miscarraige rates were higher in the group with poor prognosis (9.0% vs. 25%, p<0.003). Conclusions: Evaluation of AMH and FSH together is critical in determining clinical pregnancy rates.
目的:探讨抗苗勒管激素(AMH)和促卵泡激素(FSH)在临床妊娠预测中的作用。材料与方法:选取40例因不同不孕原因而选择体外受精/ICSI的患者作为研究对象。根据患者的AMH和FSH值分为预后好和预后差两组。比较预后良好的33个周期和预后不良的17个周期的临床妊娠率和流产率。结果:预后良好组FSH值显著低于预后不良组(5.98±1.04 mIU/mL∶13.6±3.07 mIU/mL, p < 0.01)，血清AMH水平显著高于预后不良组。(3.80±1.32 ng/mL vs 0.54±0.02 ng/mL, p<0.01)。预后良好组化学妊娠发生率是预后不良组的2倍(12例(36.3%)vs 5例(29.4%)，p < 0.01;0.02)。临床妊娠率方面，预后较好的组发生率较高(33.3%比23.5%，p<0.001)，预后较差组流产率较高(9.0%比25%，p<0.003)。结论:AMH和FSH的联合评估是决定临床妊娠率的关键。
{"title":"The predictive effect of serum AMH and FSH levels alone or in combination on fertility outcome","authors":"Zercan Kalı, Fatma Tanılır Çağıran","doi":"10.46328/aejog.v5i2.156","DOIUrl":"https://doi.org/10.46328/aejog.v5i2.156","url":null,"abstract":"Objective: To explore the roles of anti-mullerian hormone (AMH) and follicle stimulating hormone (FSH) in predicting clinical pregnancy. Materials and Methods: Forty patients who were decided on IVF/ICSI due to different infertility etiologies were included in the study. The patients were divided into two groups according to their AMH and FSH values as having a good prognosis or a poor prognosis. The clinical pregnancy and miscarriage rates of 33 cycles with good prognosis and 17 cycles with poor prognosis were compared. Results: In the good prognosis group, the FSH value was significantly lower than the poor prognosis group (5.98±1.04 mIU/mL vs. 13.6±3.07 mIU/mL, p<0.01), while the serum AMH level was significantly higher. (3.80±1.32 ng/mL vs 0.54±0.02 ng/mL, p<0.01). The rate of chemical pregnancy in the group with good prognosis was twice as high and significant compared to the group with poor prognosis (12 (36.3%) vs 5 (29.4%), p<0.02). In terms of clinical pregnancy rates, the group with good prognosis showed a higher frequency (33.3% vs. 23.5%, p<0.001), while miscarraige rates were higher in the group with poor prognosis (9.0% vs. 25%, p<0.003). Conclusions: Evaluation of AMH and FSH together is critical in determining clinical pregnancy rates.","PeriodicalId":159256,"journal":{"name":"Aegean Journal of Obstetrics and Gynecology","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135149591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The results of karyotype analysis and 22q11.2 ( DiGeorge Syndrome critical region) deletion investigation in fetal cardiac system anomalies
Objective: We aimed to determine the presence of accompanying chromosomal anomalies and 22q11.2 deletion in patients with cardiac system anomalies.
Material and Methods: In our retrospective and cross-sectional study, 99 fetuses born with cardiac anomalies were evaluated in terms of chromosomal anomalies. 36 fetuses were evaluated for 22q11.2 deletion. Fetuses who were diagnosed with prenatal congenital heart defect and underwent invasive prenatal diagnostic tests for fetal karyotyping between 01.01.2010 and 30.06.2017 at a tertiary cancer center were included in the study.
Results: Of 99 cases, 48 (48.4%) had only cardiac anomalies and 51 (51.5%) had non-cardiac anomalies. Chromosomal anomalies were found in 37 (37.4%) of the cases. Autosomal trisomy 18(43.2%) and autosomal trisomy 21(32.4%) were the most common chromosomal anomalies. The study results support the strong association of chromosomal changes and cardiac malformation, especially in septal defects, atrioventricular septal defects, and conotruncal malformations. Deletion was detected in one(2.8%) of 36 cases evaluated for 22q11.2 deletion. The fetus with this deletion had isolated tetralogy of fallot and had no extracardiac anomaly.
Conclusion: In cases with cardiac anomalies, isolated or accompanied by extracardiac anomalies, investigations should be made in terms of underlying chromosomal diseases in the perinatal evaluation. In addition, the investigation of 22q11.2 deletion in fetuses with conotruncal cardiac anomalies should be included in prenatal genetic examination.
Keywords: DiGeorge Syndrome, Fetal Anomalies, karyotype, trisomy, 22q11.2 Deletion Syndrome
{"title":"Results of karyotype analysis and 22q11.2 (DiGeorge Syndrome critical region) deletion investigation in fetal cardiac system anomalies","authors":"Zübeyde Emiralioğlu Çakır, Atalay Ekin, Altuğ Koç, Yaşar Bekir Kutbay, İlker Çakır, Muzaffer Sancı","doi":"10.46328/aejog.v5i2.140","DOIUrl":"https://doi.org/10.46328/aejog.v5i2.140","url":null,"abstract":"The results of karyotype analysis and 22q11.2 ( DiGeorge Syndrome critical region) deletion investigation in fetal cardiac system anomalies 
 Objective: We aimed to determine the presence of accompanying chromosomal anomalies and 22q11.2 deletion in patients with cardiac system anomalies.
 Material and Methods: In our retrospective and cross-sectional study, 99 fetuses born with cardiac anomalies were evaluated in terms of chromosomal anomalies. 36 fetuses were evaluated for 22q11.2 deletion. Fetuses who were diagnosed with prenatal congenital heart defect and underwent invasive prenatal diagnostic tests for fetal karyotyping between 01.01.2010 and 30.06.2017 at a tertiary cancer center were included in the study.
 Results: Of 99 cases, 48 (48.4%) had only cardiac anomalies and 51 (51.5%) had non-cardiac anomalies. Chromosomal anomalies were found in 37 (37.4%) of the cases. Autosomal trisomy 18(43.2%) and autosomal trisomy 21(32.4%) were the most common chromosomal anomalies. The study results support the strong association of chromosomal changes and cardiac malformation, especially in septal defects, atrioventricular septal defects, and conotruncal malformations. Deletion was detected in one(2.8%) of 36 cases evaluated for 22q11.2 deletion. The fetus with this deletion had isolated tetralogy of fallot and had no extracardiac anomaly.
 Conclusion: In cases with cardiac anomalies, isolated or accompanied by extracardiac anomalies, investigations should be made in terms of underlying chromosomal diseases in the perinatal evaluation. In addition, the investigation of 22q11.2 deletion in fetuses with conotruncal cardiac anomalies should be included in prenatal genetic examination.
 Keywords: DiGeorge Syndrome, Fetal Anomalies, karyotype, trisomy, 22q11.2 Deletion Syndrome","PeriodicalId":159256,"journal":{"name":"Aegean Journal of Obstetrics and Gynecology","volume":"222 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135149585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The aim of this study was to evaluate the quality, reliability, and usefulness of laparoscopıc hysterectomy videos on YouTube. Methods: A search was conducted on YouTube using the keyword " laparoscopıc hysterectomy". The search results were limited to the first 400 videos. 330 videos that met the inclusion criteria were examined. Viewer parameters such as likes and dislikes, total views, comments, and sources were evaluated. The educational content of the videos was evaluated using the Global Quality Score. Additionally, the popularity of the videos was evaluated using the Video Power Index. Upload sources were categorized as academic institutions and individual users. Results: Group 1 (low and medium quality videos) had 234 (70.9%) videos and group 2 (good and excellent quality videos) had 96 (20.1%) videos. The average views, likes, and comments in group 1 were 20589±23552 , 86±113 , and 28±31, respectively, while in group 2, they were 25571±24541 , 174±198 , and 49±42 , respectively. When the two groups were compared, no correlation was found between the length and quality of the videos.There was no difference between the groups in terms of the number of dislikes Additionally, the VPI values in group 2 were statistically higher than those in group 1 (p = 0.003). Conclusion: Only 20.1 % of laparoscopıc hysterectomy videos on YouTube are of good and excellent quality, indicating that a significant portion of videos providing laparoscopıc hysterectomy education are inadequate.
{"title":"Analyzing the quality and reliability of educational content in laparoscopic hysterectomy videos on Youtube","authors":"E. Öztürk","doi":"10.46328/aejog.v5i1.136","DOIUrl":"https://doi.org/10.46328/aejog.v5i1.136","url":null,"abstract":"Objective: The aim of this study was to evaluate the quality, reliability, and usefulness of laparoscopıc hysterectomy videos on YouTube.\u0000Methods: A search was conducted on YouTube using the keyword \" laparoscopıc hysterectomy\". The search results were limited to the first 400 videos. 330 videos that met the inclusion criteria were examined. Viewer parameters such as likes and dislikes, total views, comments, and sources were evaluated. The educational content of the videos was evaluated using the Global Quality Score. Additionally, the popularity of the videos was evaluated using the Video Power Index. Upload sources were categorized as academic institutions and individual users.\u0000Results: Group 1 (low and medium quality videos) had 234 (70.9%) videos and group 2 (good and excellent quality videos) had 96 (20.1%) videos. The average views, likes, and comments in group 1 were 20589±23552 , 86±113 , and 28±31, respectively, while in group 2, they were 25571±24541 , 174±198 , and 49±42 , respectively. When the two groups were compared, no correlation was found between the length and quality of the videos.There was no difference between the groups in terms of the number of dislikes Additionally, the VPI values in group 2 were statistically higher than those in group 1 (p = 0.003).\u0000Conclusion: Only 20.1 % of laparoscopıc hysterectomy videos on YouTube are of good and excellent quality, indicating that a significant portion of videos providing laparoscopıc hysterectomy education are inadequate.","PeriodicalId":159256,"journal":{"name":"Aegean Journal of Obstetrics and Gynecology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126313109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Objective: To identify the factors impacting the decision of declining to have prenatal diagnostic tests and to determine the reasons for declining in cases with high trisomy risk in prenatal screening tests and those who refuse to undergo prenatal diagnostic tests. Materials and methods: Cases with positive test results in first and second trimester aneuploidy screening tests were included in the study. The patients were divided into two groups those who accepted prenatal diagnostic tests (Group 1) and those who refused prenatal diagnostic tests (Group 2). The patients that refused prenatal diagnostic tests were evaluated with a questionnaire to determine the reasons for refusal. Results: 204 cases were included in the study. 44 (21.6%) of these cases wanted to have prenatal diagnostic tests, while 160 (78.4%) refused to have prenatal diagnosis tests. A significant correlation was found between the decision to refuse the prenatal diagnostic test and the mother's educational status level (p=0.035), whereas no significant correlation was found between the personalized risk ratios and the number of abortions in previous pregnancies. Among the reasons for refusal of prenatal diagnosis test, the main reason was determined to be "Termination of pregnancy is not an option". Conclusion: Pregnant women should be offered all options, including not having a prenatal screening test or a prenatal diagnostic test, by providing accurate and understandable information about the purpose and potential outcomes of prenatal screening tests. Hence, pregnant women can be provided with the opportunity to make an informed choice.
{"title":"Reasons for declining prenatal diagnostic tests and analysis of factors impacting the decision","authors":"Fırat Ökmen, Huseyin Ekici, Erdoğan Koca, Osman Ökmen, Hicran Acar Şirinoğlu","doi":"10.46328/aejog.v5i1.138","DOIUrl":"https://doi.org/10.46328/aejog.v5i1.138","url":null,"abstract":"Abstract \u0000Objective: To identify the factors impacting the decision of declining to have prenatal diagnostic tests and to determine the reasons for declining in cases with high trisomy risk in prenatal screening tests and those who refuse to undergo prenatal diagnostic tests. \u0000Materials and methods: Cases with positive test results in first and second trimester aneuploidy screening tests were included in the study. The patients were divided into two groups those who accepted prenatal diagnostic tests (Group 1) and those who refused prenatal diagnostic tests (Group 2). The patients that refused prenatal diagnostic tests were evaluated with a questionnaire to determine the reasons for refusal. \u0000Results: 204 cases were included in the study. 44 (21.6%) of these cases wanted to have prenatal diagnostic tests, while 160 (78.4%) refused to have prenatal diagnosis tests. A significant correlation was found between the decision to refuse the prenatal diagnostic test and the mother's educational status level (p=0.035), whereas no significant correlation was found between the personalized risk ratios and the number of abortions in previous pregnancies. Among the reasons for refusal of prenatal diagnosis test, the main reason was determined to be \"Termination of pregnancy is not an option\". \u0000Conclusion: Pregnant women should be offered all options, including not having a prenatal screening test or a prenatal diagnostic test, by providing accurate and understandable information about the purpose and potential outcomes of prenatal screening tests. Hence, pregnant women can be provided with the opportunity to make an informed choice.","PeriodicalId":159256,"journal":{"name":"Aegean Journal of Obstetrics and Gynecology","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128500107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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