Journal of Manipulative and Physiological Therapeutics最新文献

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IF 1.4 4区医学 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Manipulative and Physiological Therapeutics

Pub Date : 2025-07-01 DOI: 10.1016/S0161-4754(25)00131-9

引用次数: 0

Patient Satisfaction With Traditional Chinese Medicine Telemedicine Service During the COVID-19 Pandemic: A Cross-Sectional Study COVID-19大流行期间中医远程医疗服务患者满意度的横断面研究

IF 1.4 4区医学 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Manipulative and Physiological Therapeutics

Pub Date : 2025-07-01 DOI: 10.1016/j.jmpt.2025.10.047

Shanshan Xu PhD , Fai Fai Ho MPH , Talos Ming Hong Kwong BSc , Angus Siu-cheong Li PhD , Eun Hae Ha PhD , Heyu Hua PhD , Ching Liong PhD , Kwan Chi Leung PhD , Betty Huan Wang PhD , Ting Hung Leung PhD , Zhixiu Lin PhD , Samuel Yeung-Shan Wong PhD , Faming Pan PhD , Vincent Chi Ho Chung PhD

Objective

This study aimed to evaluate the satisfaction of patients with and without COVID-19 when using traditional Chinese medicine (TCM) telemedicine during the pandemic in Hong Kong.

Methods

This was a cross-sectional study of 122 COVID-19 patients and 90 non-COVID-19 patients who utilized a TCM telemedicine service provided by The Chinese University of Hong Kong Chinese Medicine Specialty Clinic cum Clinical Teaching and Research Centre during March to April 2022. A Telemedicine Satisfaction Questionnaire, consisting of factors of Information Exchange and Patient Comfort, was administered via an online survey after video consultations. Patients’ satisfaction on these aspects of satisfaction was assessed. Subgroup and linear regression analyses were conducted to explore patient characteristics associated with satisfaction with telemedicine.

Results

Overall patient satisfaction with Information Exchange was good (28.00 [4.00] out of 35), but rating on Patient Comfort was mediocre (21.00 [5.00] out of 35), with a clear preference for face-to-face consultation. Compared to non-COVID-19 patients, the total score for Information Exchange was slightly lower amongst those consulted for COVID-19, as a majority of them are new patients without a per-existing relationship with the clinician. Satisfaction tended to be higher among patients who were younger, female, better-educated, employed, and had complete COVID-19 vaccinations.

Conclusions

Despite being fairly satisfied with the TCM telemedicine service, both COVID-19 and non-COVID-19 patients expressed a preference for face-to-face consultation. While improving clinician-patient interaction during video consultation is expected to improve communication quality, it is expected that demand for face-to-face TCM services will rebound in the post-COVID era.

目的：本研究旨在评估香港地区新冠肺炎患者和非新冠肺炎患者在大流行期间使用中医远程医疗的满意度。方法：对2022年3 - 4月使用香港中文大学中医专科诊所暨临床教学研究中心提供的中医远程医疗服务的122例COVID-19患者和90例非COVID-19患者进行横断面研究。在视频会诊后，通过在线调查的方式进行远程医疗满意度问卷，包括信息交流和患者舒适度两个因素。评估患者对这些方面的满意度。采用亚组和线性回归分析探讨与远程医疗满意度相关的患者特征。结果：患者对信息交流的总体满意度较好（28.00[4.00]/ 35），但对患者舒适度的评分一般（21.00[5.00]/ 35），明显倾向于面对面咨询。与非COVID-19患者相比，咨询COVID-19的患者的信息交流总分略低，因为他们中的大多数是新患者，与临床医生没有先前存在的关系。年轻、女性、受过良好教育、有工作和完成COVID-19疫苗接种的患者满意度往往更高。结论：新冠肺炎患者和非新冠肺炎患者均对中医远程医疗服务较为满意，但更倾向于面对面咨询。虽然改善视频会诊过程中的医患互动有望提高沟通质量，但预计后疫情时代对面对面中医服务的需求将出现反弹。

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引用次数: 0

Balance Ability in Para Taekwondo Athletes: A Cross-Sectional Study 跆拳道运动员平衡能力的横断面研究。

IF 1.4 4区医学 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Manipulative and Physiological Therapeutics

Pub Date : 2025-07-01 DOI: 10.1016/j.jmpt.2025.10.062

Bihter Akınoğlu , Tuğba Kocahan

Objective

The purpose of this study was to compare the static and dynamic balance ability of para taekwondo athletes, taekwondo athletes, and sedentary healthy individuals.

Methods

This comparative cross-sectional study was conducted with 9 para taekwondo athletes, 9 taekwondo athletes, and 11 healthy individuals with sedentary lifestyles. Static balance ability and dynamic balance ability were evaluated.

Results

The 2-leg static balance test area of the sedentary healthy group was lower than that of para taekwondo athletes. The duration of the single-leg static balance test was greater in para taekwondo athletes than in other groups, and the area was greater in taekwondo athletes than in other groups. The dynamic balance area was higher in the para taekwondo group than in the sedentary group.

Conclusion

Para taekwondo athletes with upper limb deficiency at or below the elbow level had worse static 2-leg and single-leg static balance. However, the functional balance of these athletes was better compared to that of healthy individuals.

目的：比较para跆拳道运动员、跆拳道运动员和久坐健康人的静态和动态平衡能力。方法：对9名跆拳道运动员、9名跆拳道运动员和11名具有久坐生活方式的健康个体进行比较横断面研究。静平衡能力和动平衡能力进行了评价。结果：久坐健康组两腿静态平衡测试面积低于跆拳道运动员。跆拳道运动员单腿静态平衡测试持续时间大于其他组，跆拳道运动员单腿静态平衡测试面积大于其他组。para跆拳道组的动态平衡区高于久坐组。结论：肘部及以下上肢缺陷的跆拳道运动员两腿静态平衡和单腿静态平衡较差。然而，与健康个体相比，这些运动员的功能平衡更好。

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引用次数: 0

Effect of Total Resistance Exercises and Aquatic Exercises on Pain and Function of People With Knee Osteoarthritis: A Randomized Controlled Trial 全阻力运动和水上运动对膝关节骨关节炎患者疼痛和功能的影响：一项随机对照试验。

IF 1.4 4区医学 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Manipulative and Physiological Therapeutics

Pub Date : 2025-07-01 DOI: 10.1016/j.jmpt.2025.10.063

Shirin Assar MD , Farzaneh Gandomi PhD , Homayoun Abbasi PhD

Objective

This study aimed to investigate the effects of aquatic exercises (AEs) and total resistance exercises (TRX) on the pain and function of women with knee osteoarthritis.

Methods

This randomized controlled trial was conducted on 53 patients diagnosed with knee osteoarthritis. The patients were randomly allocated into 3 groups of TRX (n = 19), AEs (n = 18), and control (n = 16). The experimental groups received 8 weeks of TRX and AEs, and the control group only received medication. Outcomes were measured before, after 8-weeks of intervention, and after a 6-month follow-up. Outcomes were the visual analog scale (VAS), the quadriceps strength was examined by a dynamometer, the function was assessed using the Western Ontario and McMaster universities osteoarthritis index (WOMAC), functional capacity was measured using the timed up and go test (TUG), 40-meter walking speed (WS) test, and going up and down 8-stair (GUDS), and the quality of life (QOL) was evaluated using the SF-36.

Results

Pain and QOL improved significantly after the 8-week intervention and 6-month follow-up in both experimental groups (P < .05). However, quadriceps strength, TUG, WS, and GUDS improved significantly after the 8-week intervention and 6-month follow-up only in the TRX group (P < .05). In addition, the WOMAC improved only in the AEs group (P < .05).

Conclusions

The TRX intervention enhanced the strength and functional capacity of the patients with knee osteoarthritis more effectively compared to the AEs, while improving pain and QOL were similar to the AEs.

目的：探讨水上运动（ae）和全阻力运动（TRX）对女性膝关节骨性关节炎患者疼痛和功能的影响。方法：对53例诊断为膝骨关节炎的患者进行随机对照试验。将患者随机分为TRX组（n = 19）、ae组（n = 18）和对照组（n = 16）。实验组给予8周TRX和ae治疗，对照组仅给予药物治疗。分别在干预前、干预8周后和随访6个月后测量结果。结果为视觉模拟量表（VAS），股四头肌力量用测力仪检测，功能用西安大略省和麦克马斯特大学骨关节炎指数（WOMAC）评估，功能能力用时间起跑测试（TUG）测量，40米步行速度（WS）测试，上下8级楼梯（GUDS）测量，生活质量（QOL）用SF-36评估。结果：两组患者在干预8周、随访6个月后疼痛和生活质量均有显著改善（P < 0.05）。然而，仅TRX组在干预8周和随访6个月后，股四头肌力量、TUG、WS和GUDS均有显著改善（P < 0.05）。此外，仅ae组WOMAC有改善（P < 0.05）。结论：与ae相比，TRX干预更有效地增强了膝关节骨性关节炎患者的力量和功能能力，而改善的疼痛和生活质量与ae相似。

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引用次数: 0

Reliability of a Visual-Cognitive Technology in Measuring Reaction Times: Associations with Age, Activity Level, and Grip Strength 一种测量反应时间的视觉认知技术的可靠性：与年龄、活动水平和握力的关系。

IF 1.4 4区医学 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Manipulative and Physiological Therapeutics

Pub Date : 2025-07-01 DOI: 10.1016/j.jmpt.2025.10.054

Tülay Çevik Saldıran PT, PhD , Abdurrahman Tanhan PhD , Rabia Çelikel PhD , Erhan Dinçer PhD

Objectives

The purpose of this study was to assess the reliability of a visual-cognitive system for measuring simple, serial, and choice reaction times, and examined their associations with age, physical activity, and grip strength.

Methods

Ninety participants were divided into 3 age groups (18-34, 35-64, and 65+ years). Reaction times were assessed using a commercially available visual-cognitive training platform. Grip strength was measured with a hand dynamometer, and activity level was evaluated using the International Physical Activity Questionnaire–Short Form (IPAQ-SF).

Results

Choice reaction times differed significantly by age, with younger adults responding faster than older adults (P < .05). Simple and serial reaction times were also shortest in the youngest group. Significant associations were found between reaction times, age, and activity level (P < .05), with no significant differences by sex (P > .05). Intra-rater reliability was highest for simple reaction time (ICC = 0.70-0.80), followed by choice (ICC = 0.66-0.76) and serial (ICC = 0.62-0.73). Between-day reliability was good for simple (ICC = 0.81) and serial (ICC = 0.76) reaction times, and moderate for choice (ICC = 0.63). Inter-rater reliability was good across all measures (ICCs ≥ 0.70).

Conclusions

Choice reaction time appears to be particularly sensitive to age-related differences. Higher activity levels and greater grip strength are associated with faster responses. The tested visual-cognitive technology demonstrated acceptable reliability for assessing performance-related reaction times.

目的：本研究的目的是评估测量简单、连续和选择反应时间的视觉认知系统的可靠性，并检查它们与年龄、身体活动和握力的关系。方法：90名参与者分为18-34岁、35-64岁和65岁以上3个年龄组。反应时间使用市售的视觉认知训练平台进行评估。用手测力仪测量握力，用国际体育活动问卷-短表格（IPAQ-SF）评估活动水平。结果：选择反应时间因年龄而有显著差异，年轻人的反应速度快于老年人（P < 0.05）。在最年轻的一组中，简单和连续的反应时间也最短。反应时间、年龄和活动量之间存在显著相关性（P < 0.05），性别之间无显著差异（P < 0.05）。简单反应时间的信度最高（ICC = 0.70-0.80），其次是选择（ICC = 0.66-0.76）和序列（ICC = 0.62-0.73）。简单反应时间（ICC = 0.81）和连续反应时间（ICC = 0.76）的日间信度较好，选择反应时间的日间信度中等（ICC = 0.63）。所有测量的量表间信度均良好（ICCs≥0.70）。结论：选择反应时间似乎对年龄相关的差异特别敏感。更高的活动水平和更强的握力与更快的反应有关。测试的视觉认知技术在评估与表现相关的反应时间方面证明了可接受的可靠性。

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引用次数: 0

Effect of Different Dance Rhythms on the Recovery Period of the Autonomic Nervous System 不同舞蹈节奏对自主神经系统恢复期的影响。

IF 1.4 4区医学 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Manipulative and Physiological Therapeutics

Pub Date : 2025-07-01 DOI: 10.1016/j.jmpt.2025.10.056

Ruixue Zhao MA , Jiayi Li BA , Jiameng Wang PhD

Objectives

The purpose of this study was to investigate the impact of various dance rhythms on heart rate variability (HRV), to determine the relationship between dance rhythms and HRV during the recovery period, and to provide reliable recommendations for dance interventions in the field of cardiovascular disease.

Method

A total of 160 college students enrolled at Yan’an University as of September 1, 2023 were randomly selected and assigned to 3 groups. Each group underwent dance interventions at rhythms of 60 beats per minute (bpm), 100 bpm, and 140 bpm, respectively, conducted in 3 sessions, each lasting 5 minutes. Heart rate recovery and HRV data were collected before and after the tests for statistical analysis.

Results

Analysis of HRV indicators before the dance rhythm intervention showed no statistically significant difference between men and women (P > .05). However, HRV and the standard deviation of normal-to-normal intervals (SDNN) during the recovery period were statistically significantly different between men and women under different dance rhythm interventions (P < .05). Moreover, HRV and SDNN values after the intervention at 140 bpm were significantly lower than those after the interventions at 60 bpm and 100 bpm (P < .05).

Conclusion

These study results demonstrate that dance rhythm significantly affected HRV. This information may be potentially helpful in informing further research studies for dance interventions in the field of cardiovascular diseases.

目的：本研究旨在探讨不同舞蹈节奏对心率变异性（HRV）的影响，确定恢复期舞蹈节奏与HRV的关系，为心血管疾病领域的舞蹈干预提供可靠建议。方法：随机抽取延安大学2023年9月1日在校生160名，分为3组。每组分别以每分钟60拍、每分钟100拍和每分钟140拍的节奏进行舞蹈干预，分3次进行，每次持续5分钟。采集试验前后心率恢复和HRV数据进行统计分析。结果：舞蹈节奏干预前HRV指标分析，男女差异无统计学意义（P < 0.05）。而在不同舞蹈节奏干预下，恢复期间HRV和正常-正常间隔标准差（SDNN）在男女之间差异有统计学意义（P < 0.05）。干预140 bpm后HRV和SDNN值显著低于干预60 bpm和100 bpm后（P < 0.05）。结论：舞蹈节奏对心率变异有显著影响。这些信息可能对进一步研究舞蹈干预心血管疾病领域的研究有潜在的帮助。

{"title":"Effect of Different Dance Rhythms on the Recovery Period of the Autonomic Nervous System","authors":"Ruixue Zhao MA , Jiayi Li BA , Jiameng Wang PhD","doi":"10.1016/j.jmpt.2025.10.056","DOIUrl":"10.1016/j.jmpt.2025.10.056","url":null,"abstract":"<div><h3>Objectives</h3><div>The purpose of this study was to investigate the impact of various dance rhythms on heart rate variability (HRV), to determine the relationship between dance rhythms and HRV during the recovery period, and to provide reliable recommendations for dance interventions in the field of cardiovascular disease.</div></div><div><h3>Method</h3><div>A total of 160 college students enrolled at Yan’an University as of September 1, 2023 were randomly selected and assigned to 3 groups. Each group underwent dance interventions at rhythms of 60 beats per minute (bpm), 100 bpm, and 140 bpm, respectively, conducted in 3 sessions, each lasting 5 minutes. Heart rate recovery and HRV data were collected before and after the tests for statistical analysis.</div></div><div><h3>Results</h3><div>Analysis of HRV indicators before the dance rhythm intervention showed no statistically significant difference between men and women (<em>P</em> > .05). However, HRV and the standard deviation of normal-to-normal intervals (SDNN) during the recovery period were statistically significantly different between men and women under different dance rhythm interventions (<em>P</em> < .05). Moreover, HRV and SDNN values after the intervention at 140 bpm were significantly lower than those after the interventions at 60 bpm and 100 bpm (<em>P</em> < .05).</div></div><div><h3>Conclusion</h3><div>These study results demonstrate that dance rhythm significantly affected HRV. This information may be potentially helpful in informing further research studies for dance interventions in the field of cardiovascular diseases.</div></div>","PeriodicalId":16132,"journal":{"name":"Journal of Manipulative and Physiological Therapeutics","volume":"48 6","pages":"Pages 662-670"},"PeriodicalIF":1.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145482317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Chest Physiotherapy on Respiratory Capacity in Patients With Severe Acute Respiratory Syndrome Coronavirus 2: A Randomized Controlled Trial 胸部物理治疗对冠状病毒2型重症急性呼吸综合征患者呼吸能力的影响：一项随机对照试验

IF 1.4 4区医学 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Manipulative and Physiological Therapeutics

Pub Date : 2025-07-01 DOI: 10.1016/j.jmpt.2025.10.013

Fatemeh Ehsani , Rasool Bagheri , Marzieh Mortezanejad , Rozita Hedayati , Atefeh Aminianfar , Mohammad Memarian

Objective

The purpose of this study was to evaluate the effects of chest physiotherapy on respiratory function during rest sitting and stationary bicycle in participants hospitalized for a period with respiratory involvement after SARS-CoV-2 infection.

Methods

This study was a randomized, single-blinded, controlled study. Forty-four participants after SARS-CoV-2 met the inclusion criteria and were randomly assigned to the 2 groups. The study intervention included a program of 10 sessions of supervised chest physiotherapy (intervention) and without any intervention (control) groups. They were assessed on 2 sessions before and after the intervention according to the respiratory function, including time of inspiration (TI), time of expiration (TE), peak inspiratory flow (PIF), peak expiratory flow (PEF), forced vital capacity (FVC), and forced expiratory volume 1/forced vital capacity (FEV1/FVC). This assessment was done on 2 situations: during rest sitting position on the table and during stationary bicycle for 20 minutes.

Results

Analysis of variance revealed that the effect of time was significant for the PEF and FVC. Moreover, the interaction effect of “time and group” was significant for the TE, PEF, FEV1, and FEV1/FVC. A group difference was revealed for the TE, FEV1, and FEV1/FVC after the intervention. The paired t-test indicated that the PEF, FEV1, and FEV1/FVC increased in the intervention group when the spirometry was done in the sitting position (P ≤ .05). Independent t-test also showed that the FEV1 (P = .008) and FEV1/FVC (P = .004) significantly increased in the intervention group compared to the control group during sitting spirometry (P ≤ .05). Moreover, FEV1/FVC (P = .002) was decreased in the intervention group when the spirometry was done during stationary bicycle.

Conclusion

In this study, patients after SARS-CoV-2 had improved respiratory functions and functional activities after 10 sessions of therapy.

目的：本研究的目的是评估胸部物理治疗对SARS-CoV-2感染后住院一段时间呼吸受累患者休息坐骑和固定自行车呼吸功能的影响。方法：本研究为随机、单盲、对照研究。44名符合纳入标准的SARS-CoV-2患者被随机分为两组。研究干预包括10个疗程的有监督的胸部物理治疗（干预）和没有任何干预（对照组）组。根据呼吸功能，包括吸气时间（TI）、呼气时间（TE）、吸气峰值流量（PIF）、呼气峰值流量（PEF）、用力肺活量（FVC）、用力呼气容积1/用力肺活量（FEV1/FVC），分别在干预前后2个时段进行评估。这项评估是在两种情况下进行的：休息时，坐在桌子上和在固定自行车上20分钟。结果：方差分析显示，时间对PEF和FVC的影响显著。TE、PEF、FEV1、FEV1/FVC均存在“时间-组”交互作用。干预后TE、FEV1、FEV1/FVC均有组间差异。配对t检验显示，干预组在坐位测肺时PEF、FEV1、FEV1/FVC均升高（P≤0.05）。独立t检验还显示，干预组坐测肺时FEV1 （P = 0.008）和FEV1/FVC （P = 0.004）较对照组显著升高（P≤0.05）。此外，干预组的FEV1/FVC （P = 0.002）在固定自行车运动中进行肺活量测定时降低。结论：在本研究中，经过10个疗程的治疗，SARS-CoV-2患者的呼吸功能和功能活动有所改善。

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引用次数: 0

Effect of Different Intensities of Progressive Physical Exercise on Growth Plate Closure in Young Rats 不同强度进行性体育锻炼对幼鼠生长板闭合的影响。

IF 1.4 4区医学 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Manipulative and Physiological Therapeutics

Pub Date : 2025-07-01 DOI: 10.1016/j.jmpt.2025.10.014

Márcia R. de Andrade MSc , Alessandro de Oliveira PhD , Luan A. Pereira MSc , Ismael A.L. Santos BSc , Maria Eduarda P. Campos BSc , Luna S.C. Vaz BSc , Laila C.M. Damázio PhD

Objective

The aim of this study was to investigate the morphology of growth plates (GP) in young rats submitted to high and medium-intensity physical exercise.

Methods

The sample consisted of 24 Wistar rats divided into 3 groups: untrained controls (RC), high-intensity physical exercise (R1), and medium-intensity physical exercise (R2). A weight-adjusted ladder training protocol was adopted (five times a week for 4 weeks). Histomorphometric analysis of the GP of the right tibia was performed in a longitudinal section after staining with hematoxylin-eosin and Gomori’s trichrome, in addition to cell counts and GP thickness measurements. One-way ANOVA and Tukey’s post-test (α < 0.05) were used to analyze the means.

Results

The GP presented inferior thickness and chondrocyte counts in the group that underwent high-intensity physical training (355.5 μm and 1157.3) compared to the control (407.6 μm and 1329.7) and medium-intensity groups (312.4 μm and 1328.5).

Conclusion

High and medium-intensity training promoted a reduction in the GP of young rats compared to the control group. Therefore, ladder training protocols may anticipate GP closure in young rats, thus impairing tibial length in these animals.

目的：研究幼龄大鼠高、中强度体育锻炼后生长板的形态变化。方法：采用Wistar大鼠24只，随机分为3组：未训练对照组（RC）、高强度体育锻炼组（R1）和中强度体育锻炼组（R2）。采用调整体重的阶梯训练方案（每周5次，持续4周）。在苏木精-伊红和Gomori三色染色后，在纵向切片上对右胫骨GP进行组织形态学分析，并进行细胞计数和GP厚度测量。采用单因素方差分析和Tukey事后检验（α < 0.05）进行均值分析。结果：与对照组（407.6 μm和1329.7）和中等强度组（312.4 μm和1328.5）相比，高强度运动组（355.5 μm和1157.3）的GP厚度和软骨细胞计数较低。结论：与对照组相比，高强度和中等强度的训练促进了年轻大鼠GP的降低。因此，阶梯训练方案可能预期幼鼠GP关闭，从而损害这些动物的胫骨长度。

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引用次数: 0

Effect of Massage on Regulating Oxidative Stress in Intervertebral Disc Degeneration in a Rat Model 按摩对大鼠椎间盘退变模型氧化应激的调节作用。

IF 1.4 4区医学 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Manipulative and Physiological Therapeutics

Pub Date : 2025-07-01 DOI: 10.1016/j.jmpt.2025.10.029

Song Wang B.S.Med , Yanping Hu MM , Meijia Ke B.S.Med , Xin Zhao MM , Heran Xiong MM , Chao Xiang MM , Zhen Ruan MM , Shenghua He MM

Objective

This study investigated the potential mechanism by which massage protects against intervertebral disc (IVD) trauma progression.

Methods

A total of 24 male Sprague-Dawley rats were randomly divided into sham, model, and model plus massage groups (8 rats per group). A rat model of lumbar IVD trauma was established by needle puncture combined with intradiscal tumor necrosis factor-alpha (TNF-α) injection. Two days after modeling, rats received massage therapy on the BL23 acupoint once daily. Pain-related behavioral tests were conducted. Hematoxylin-eosin staining was employed for histopathological observation of lumbar IVDs. The levels of oxidative stress-related markers were determined using assay kits. Western blotting was utilized for estimating the Janus kinase 2/signal transducer and activator of transcription 3 (JAK2/STAT3) signaling-associated protein expression in rat lumbar IVDs.

Results

Rats in the massage group had less mechanical allodynia and thermal hyperalgesia. Following massage, the pathological damages in rat lumbar IVDs were improved, reactive oxygen species and malondialdehyde levels were reduced, and superoxide dismutase and glutathione contents were increased. The phosphorylation of JAK2 and STAT3 in lumbar IVDs was inhibited in rats with massage therapy.

Conclusions

Massage improves pain-related behaviors, inhibits oxidative stress, and suppresses the JAK2/STAT3 signaling pathway in puncture-induced rats.

目的：探讨按摩预防椎间盘外伤进展的可能机制。方法：将24只雄性Sprague-Dawley大鼠随机分为假手术组、模型组、模型加推拿组，每组8只。采用针刺联合椎间盘内注射肿瘤坏死因子-α (TNF-α)建立大鼠腰椎IVD损伤模型。造模2 d后，给予大鼠BL23穴按摩治疗，每日1次。进行了与疼痛相关的行为测试。采用苏木精-伊红染色对腰椎ivd进行组织病理学观察。使用测定试剂盒测定氧化应激相关标志物的水平。Western blotting检测大鼠腰椎ivd中Janus kinase 2/signal transducor and activator of transcription 3 （JAK2/STAT3）信号相关蛋白表达。结果：按摩组大鼠机械性异常痛和热痛觉过敏明显减少。按摩后，大鼠腰椎IVDs病理损伤得到改善，活性氧和丙二醛水平降低，超氧化物歧化酶和谷胱甘肽含量升高。按摩可抑制大鼠腰椎ivd中JAK2和STAT3的磷酸化。结论：按摩可改善针刺大鼠的疼痛相关行为，抑制氧化应激，抑制JAK2/STAT3信号通路。

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引用次数: 0

Effect of Transcutaneous Electrical Acupoint Stimulation on Sleep Quality and Menopausal Symptoms in Postmenopausal Women: A Randomized Controlled Trial 经皮穴位电刺激对绝经后妇女睡眠质量和更年期症状的影响：一项随机对照试验。

IF 1.4 4区医学 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Manipulative and Physiological Therapeutics

Pub Date : 2025-07-01 DOI: 10.1016/j.jmpt.2025.10.052

Somaye Parvandi MSc , Sousan Heydarpour PhD , Behnam Khaledi MSc , Fatemeh Heydarpour PhD

Objectives

This randomized controlled trial aimed to evaluate the effects of transcutaneous electrical acupoint stimulation (TEAS) on sleep quality and menopausal symptoms in postmenopausal women.

Methods

A total of 69 eligible postmenopausal women were recruited and randomly assigned to 1 of 3 groups: experimental TEAS, sham, or control (n = 23 each), using a block randomization method. The TEAS group received cutaneous electrical stimulation at 5 specific acupuncture points, while the sham group received stimulation at nonrelated points, and the control group received no intervention, all groups received routine primary care. Outcome measures included the Pittsburgh Sleep Quality Index (PSQI) and the Menopause Rating Scale (MRS), administered at baseline, immediately after the intervention, and one month postintervention. Data were analyzed using SPSS24, Kruskal–Wallis, Mann–Whitney, Toki and Chi-square tests. A significance level of P < .05 was considered significant.

Results

Data from 65 participants were analyzed after accounting for exclusions. At baseline, there were no significant differences in PSQI scores across the 3 groups. However, the TEAS group showed significantly greater improvement in PSQI scores immediately after the intervention (7.36 ± 3.21 vs 9.36 ± 2.38 and 9.76 ± 2.46, P = .012) and 1 month later (6.90 ± 2.97 vs 9.04 ± 2.62 and 9.61 ± 2.33, P = .003) compared to the sham and control groups. Although no significant differences in MRS scores were observed immediately postintervention, a significant reduction in menopausal symptoms was noted in the TEAS group 1 month later (26.18 ± 4.83 vs 29.95 ± 5.65 and 27.42 ± 4.15, P = .042).

Conclusion

TEAS appeared to be effective in improving sleep quality and reducing menopausal symptoms in postmenopausal women.

Trial registration

Iranian Clinical Trials Registry IRCT20130812014333N167 (registered, 18/04/2021).

目的：本随机对照试验旨在评估经皮穴位电刺激（TEAS）对绝经后妇女睡眠质量和更年期症状的影响。方法：采用分组随机法，共招募69名符合条件的绝经后妇女，随机分为实验组、假手术组或对照组（n = 23）。tea组在5个特定穴位进行皮电刺激，假手术组在不相关穴位进行皮电刺激，对照组不进行干预，所有组均进行常规初级保健。结果测量包括匹兹堡睡眠质量指数（PSQI）和更年期评定量表（MRS），分别在基线、干预后立即和干预后一个月进行。采用SPSS24、Kruskal-Wallis、Mann-Whitney、Toki和卡方检验对数据进行分析。结果：在排除因素后，对65名参与者的数据进行了分析。在基线时，三组间PSQI评分无显著差异。然而，与假手术组和对照组相比，干预后立即（7.36±3.21 vs 9.36±2.38和9.76±2.46,P = 0.012）和1个月后（6.90±2.97 vs 9.04±2.62和9.61±2.33,P = 0.003）的PSQI评分明显改善。虽然干预后立即观察到MRS评分无显著差异，但1个月后tea组的更年期症状明显减轻（26.18±4.83 vs 29.95±5.65和27.42±4.15,P = 0.042）。结论：tea对改善绝经后妇女的睡眠质量和减轻更年期症状有效。试验注册：伊朗临床试验注册中心IRCT20130812014333N167（注册，18/04/2021）。

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