Pub Date : 2024-07-02DOI: 10.1007/s10958-024-07219-5
O. Grigorenko, M. Borysenko, O. Boychuk, L. Vasil’eva
{"title":"Free Vibrations of Open Cylindrical Shells with Various Elliptic Cross Sections","authors":"O. Grigorenko, M. Borysenko, O. Boychuk, L. Vasil’eva","doi":"10.1007/s10958-024-07219-5","DOIUrl":"https://doi.org/10.1007/s10958-024-07219-5","url":null,"abstract":"","PeriodicalId":16216,"journal":{"name":"Journal of Mathematical Sciences","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141688371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-02DOI: 10.1007/s10958-024-07223-9
O. Chernukha, Y. Bilushchak
{"title":"Mathematical Modeling of the Processes of Convective Diffusion and Sorption in a Three-Layer Porous Body. II. Quantitative Analysis of the Concentration of Impurity Particles on the Boundaries of Phase Contact","authors":"O. Chernukha, Y. Bilushchak","doi":"10.1007/s10958-024-07223-9","DOIUrl":"https://doi.org/10.1007/s10958-024-07223-9","url":null,"abstract":"","PeriodicalId":16216,"journal":{"name":"Journal of Mathematical Sciences","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141687328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-02DOI: 10.1007/s10958-024-07220-y
N. Vaysfeld, Z. Zhuravlova
{"title":"Response of a Poroelastic Semi-Infinite Strip to the Compression Acting Upon Its Lateral Sides","authors":"N. Vaysfeld, Z. Zhuravlova","doi":"10.1007/s10958-024-07220-y","DOIUrl":"https://doi.org/10.1007/s10958-024-07220-y","url":null,"abstract":"","PeriodicalId":16216,"journal":{"name":"Journal of Mathematical Sciences","volume":"319 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141686668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-02DOI: 10.1007/s10958-024-07221-x
V. Pechuk, T. S. Krasnopolska
{"title":"Estimation of the Largest Lyapunov Exponent for a Model of Cross-Shaped Waves in a Rectangular Channel of Finite Size","authors":"V. Pechuk, T. S. Krasnopolska","doi":"10.1007/s10958-024-07221-x","DOIUrl":"https://doi.org/10.1007/s10958-024-07221-x","url":null,"abstract":"","PeriodicalId":16216,"journal":{"name":"Journal of Mathematical Sciences","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141684296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-14DOI: 10.1007/s10958-024-07052-w
Moussa Benoumhani, B. Heim, M. Neuhauser
{"title":"ASYMPTOTIC NORMALITY OF THE COEFFICIENTS OF THE MORGAN-VOYCE POLYNOMIALS","authors":"Moussa Benoumhani, B. Heim, M. Neuhauser","doi":"10.1007/s10958-024-07052-w","DOIUrl":"https://doi.org/10.1007/s10958-024-07052-w","url":null,"abstract":"","PeriodicalId":16216,"journal":{"name":"Journal of Mathematical Sciences","volume":"32 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141340251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-13DOI: 10.1007/s10958-024-07126-9
Alexey Karapetyants
{"title":"EDITORIAL TO THE SPECIAL ISSUE “OTHA 2023: ADVANCES ON OPERATOR THEORY AND HARMONIC ANALYSIS” OF THE JOURNAL OF MATHEMATICAL SCIENCES (SERIES A)","authors":"Alexey Karapetyants","doi":"10.1007/s10958-024-07126-9","DOIUrl":"https://doi.org/10.1007/s10958-024-07126-9","url":null,"abstract":"","PeriodicalId":16216,"journal":{"name":"Journal of Mathematical Sciences","volume":"45 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141350041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-12eCollection Date: 2024-06-01DOI: 10.1089/bioe.2022.0041
Amanda Sales Conniff, Jared Tur, Kristopher Kohena, Min Zhang, Justin Gibbons, Loree C Heller
Background: Tissues, such as skeletal muscle, have been targeted for the delivery of plasmid DNA (pDNA) encoding vaccines and therapeutics. The application of electric pulses (electroporation or electrotransfer) increases cell membrane permeability to enhance plasmid delivery and expression. However, the molecular effects of DNA electrotransfer on the muscle tissue are poorly characterized.
Materials and methods: Four hours after intramuscular plasmid electrotransfer, we evaluated gene expression changes by RNA sequencing. Differentially expressed genes were analyzed by gene ontology (GO) pathway enrichment analysis.
Results: GO analysis highlighted many enriched molecular functions. The terms regulated by pulse application were related to muscle stress, the cytoskeleton and inflammation. The terms regulated by pDNA injection were related to a DNA-directed response and its control. Several terms regulated by pDNA electrotransfer were similar to those regulated by pulse application. However, the terms related to pDNA injection differed, focusing on entry of the plasmid into the cells and intracellular trafficking.
Conclusion: Each muscle stimulus resulted in specific regulated molecular functions. Identifying the unique intrinsic molecular changes driven by intramuscular DNA electrotransfer will aid in the design of preventative and therapeutic gene therapies.
背景：骨骼肌等组织已成为输送编码疫苗和治疗药物的质粒 DNA（pDNA）的目标。应用电脉冲（电穿孔或电转移）可提高细胞膜的通透性，从而增强质粒的输送和表达。然而，DNA电转移对肌肉组织的分子影响还不甚明了：肌肉内质粒电转移四小时后，我们通过 RNA 测序评估了基因表达的变化。通过基因本体（GO）通路富集分析对差异表达基因进行了分析：结果：GO 分析强调了许多富集的分子功能。脉冲应用调控的术语与肌肉应激、细胞骨架和炎症有关。pDNA注射调节的术语与DNA定向反应及其控制有关。pDNA 电转移调节的几个术语与脉冲应用调节的术语相似。然而，与pDNA注射相关的术语有所不同，主要集中在质粒进入细胞和细胞内贩运方面：结论：每种肌肉刺激都会导致特定的分子功能调节。确定肌肉内 DNA 电转移所驱动的独特内在分子变化将有助于设计预防性和治疗性基因疗法。
{"title":"DNA Electrotransfer Regulates Molecular Functions in Skeletal Muscle.","authors":"Amanda Sales Conniff, Jared Tur, Kristopher Kohena, Min Zhang, Justin Gibbons, Loree C Heller","doi":"10.1089/bioe.2022.0041","DOIUrl":"10.1089/bioe.2022.0041","url":null,"abstract":"<p><strong>Background: </strong>Tissues, such as skeletal muscle, have been targeted for the delivery of plasmid DNA (pDNA) encoding vaccines and therapeutics. The application of electric pulses (electroporation or electrotransfer) increases cell membrane permeability to enhance plasmid delivery and expression. However, the molecular effects of DNA electrotransfer on the muscle tissue are poorly characterized.</p><p><strong>Materials and methods: </strong>Four hours after intramuscular plasmid electrotransfer, we evaluated gene expression changes by RNA sequencing. Differentially expressed genes were analyzed by gene ontology (GO) pathway enrichment analysis.</p><p><strong>Results: </strong>GO analysis highlighted many enriched molecular functions. The terms regulated by pulse application were related to muscle stress, the cytoskeleton and inflammation. The terms regulated by pDNA injection were related to a DNA-directed response and its control. Several terms regulated by pDNA electrotransfer were similar to those regulated by pulse application. However, the terms related to pDNA injection differed, focusing on entry of the plasmid into the cells and intracellular trafficking.</p><p><strong>Conclusion: </strong>Each muscle stimulus resulted in specific regulated molecular functions. Identifying the unique intrinsic molecular changes driven by intramuscular DNA electrotransfer will aid in the design of preventative and therapeutic gene therapies.</p>","PeriodicalId":16216,"journal":{"name":"Journal of Mathematical Sciences","volume":"132 1","pages":"80-90"},"PeriodicalIF":1.6,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11304878/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74205618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-11DOI: 10.1007/s10958-024-07168-z
M. Sheremeta, O. Mulyava
{"title":"On the relative growth of entire Dirichlet series with respect to Dirichlet series absolutely converging in half-plane","authors":"M. Sheremeta, O. Mulyava","doi":"10.1007/s10958-024-07168-z","DOIUrl":"https://doi.org/10.1007/s10958-024-07168-z","url":null,"abstract":"","PeriodicalId":16216,"journal":{"name":"Journal of Mathematical Sciences","volume":"79 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141357879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-11DOI: 10.1007/s10958-024-07170-5
Mariia V. Stefanchuk
{"title":"On exponential asymptotics of ring Q-homeomorphisms at infinity","authors":"Mariia V. Stefanchuk","doi":"10.1007/s10958-024-07170-5","DOIUrl":"https://doi.org/10.1007/s10958-024-07170-5","url":null,"abstract":"","PeriodicalId":16216,"journal":{"name":"Journal of Mathematical Sciences","volume":"37 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141358871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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