Journal of Medical Imaging and Radiation Oncology最新文献_第7页

A cost-effectiveness analysis of stereotactic ablative radiotherapy versus conventionally fractionated radiotherapy in the management of stage 1 non-small-cell lung cancer: Results from the TROG 09.02 CHISEL study 立体定向消融放疗与传统分次放疗在非小细胞肺癌一期治疗中的成本效益分析：TROG 09.02 CHISEL研究结果。

IF 2.2 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Medical Imaging and Radiation Oncology

Pub Date : 2024-10-09 DOI: 10.1111/1754-9485.13755

Adam Byrne, Richard De Abreu Lourenco, Ramkumar Govindaraj, David Ball, Hien Le

Introduction

Stereotactic ablative radiotherapy (SABR) is a standard of care treatment for medically inoperable early-stage non-small-cell lung cancer (NSCLC). The CHISEL trial was a phase 3 randomised controlled trial that compared SABR to conventional radiation therapy (CRT). Using patient-level data, we compared the cost-effectiveness of SABR and CRT for early-stage NSCLC.

Methods

Data on treatment exposure, outcomes (recurrence, survival) and quality of life (QoL; EORTC QLQ-C30) were sourced from the trial. Quality-adjusted life years (QALYs) were estimated for the trial period using Australian utility weights for the EORTC QLQ-C30-derived QLU-C10D. Costs related to simulation, planning, delivery, verification and post-treatment monitoring were estimated by applying Australian Medicare Benefits Schedule fees. The costs of post-progression therapy and grade ≥3 toxicity were estimated using trial data and relevant literature sources. Cost-effectiveness was investigated as the incremental cost per QALY gained for SABR compared to CRT.

Results

Complete QoL data were available for 21 patients: 14 in the SABR arm and 7 in the CRT arm. Mean QALYs discounted at 5% per annum were similar between arms: 12.68 months for SABR and 12.12 months for CRT. The mean costs of delivering SABR and CRT were $4763 and $6817, respectively. The costs of monitoring were similar in both arms, $4856 and $4853 for SABR and CRT. The mean costs of post-progression therapy were $24,572 for SABR and $42,801 for CRT. The mean costs of grade ≥3 toxicity were $809 in the SABR arm and $132 in the CRT arm. Therefore, the total mean cost for SABR over the period of interest was lower for SABR than CRT. Given lower mean costs and numerically higher QALYs for SABR compared with CRT, an incremental cost-effectiveness ratio was not calculated.

Conclusion

Compared to CRT, SABR is a cost-effective treatment for early-stage NSCLC as the estimated upfront treatment cost and the cost of subsequent care are lower for SABR for comparable mean QALYs. Assessment of the lifetime QALYs and projections of cost estimation will provide a better indication of the long-term cost-effectiveness of SABR.

简介立体定向消融放射治疗（SABR）是治疗无法手术的早期非小细胞肺癌（NSCLC）的标准疗法。CHISEL试验是一项3期随机对照试验，比较了SABR和传统放疗（CRT）。利用患者层面的数据，我们比较了 SABR 和 CRT 治疗早期 NSCLC 的成本效益：方法：有关治疗暴露、结果（复发、生存）和生活质量（QoL；EORTC QLQ-C30）的数据均来自试验。使用澳大利亚效用权重对 EORTC QLQ-C30 衍生的 QLU-C10D 对试验期间的质量调整生命年（QALYs）进行了估算。与模拟、计划、实施、验证和治疗后监测相关的成本是通过应用澳大利亚医疗保险福利表费用进行估算的。进展后治疗和≥3级毒性的成本是根据试验数据和相关文献资料估算的。与 CRT 相比，SABR 的成本效益是每 QALY 增益的增量成本：有 21 名患者获得了完整的 QoL 数据：结果：21 位患者获得了完整的 QoL 数据：14 位在 SABR 治疗组，7 位在 CRT 治疗组。两组的平均 QALYs（QALYs）按每年 5%折算，结果相似：SABR 为 12.68 个月，CRT 为 12.12 个月。实施 SABR 和 CRT 的平均成本分别为 4763 美元和 6817 美元。两组的监测成本相似，SABR 和 CRT 分别为 4856 美元和 4853 美元。SABR 和 CRT 进展后治疗的平均费用分别为 24,572 美元和 42,801 美元。SABR 治疗组≥3 级毒性的平均费用为 809 美元，CRT 治疗组为 132 美元。因此，在关注期内，SABR 的总平均成本低于 CRT。鉴于与 CRT 相比，SABR 的平均成本更低，QALYs 数值更高，因此没有计算增量成本效益比：结论：与 CRT 相比，SABR 是一种治疗早期 NSCLC 的经济有效的方法，因为在平均 QALY 值相当的情况下，SABR 的预估治疗成本和后续护理成本更低。对终生质量调整生命年的评估和成本估算的预测将更好地说明 SABR 的长期成本效益。

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引用次数: 0

A comparative study of hysterosalpingograms from 40 years ago 40 年前子宫输卵管造影对比研究

IF 2.2 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Medical Imaging and Radiation Oncology

Pub Date : 2024-10-08 DOI: 10.1111/1754-9485.13743

Christine M Acton

引用次数: 0

Head, face and neck injury patterns for electric scooter accidents identified on computed tomography scanning: Does legislative change enforcing safer riding practices have an impact on morbidity for significant head, face and neck trauma? 通过计算机断层扫描确定电动滑板车事故的头部、面部和颈部损伤模式：加强骑行安全的立法变革是否会对重大头面部和颈部创伤的发病率产生影响？

IF 2.2 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Medical Imaging and Radiation Oncology

Pub Date : 2024-10-07 DOI: 10.1111/1754-9485.13788

Nicholas Watson, Brett Droder, Gary Mitchell, Craig Hacking

Introduction

The purpose of this study is to review whether legislative change enforcing safer riding conditions for Electric Scooters (E-Scooter), regardless of other factors, had an impact on reducing significant head, facial and neck trauma. Additionally, to identify the radiological injury patterns for head, face and neck injuries identified on CT imaging for a patient's initial presentation to the emergency department (ED) resulting from an E-Scooter accident.

Methods

A retrospective single-centre observational study at a metropolitan tertiary ED of patients presenting after an E-Scooter accident comparing 6 months before and after legislative change.

Results

Four hundred and forty-three patients presented following an E-Scooter accident: 191 patients 6 months before and 252 patients 6 months after legislative change. One hundred and sixty-two patients pre- and 217 patients post-legislative change had negative CT studies. Twenty-nine patients pre- and 35 patients post-legislative change had CT studies demonstrating significant head, face or neck trauma. The most common type of intracranial bleeding was subarachnoid haemorrhage followed by subdural haemorrhage with a significant proportion (41%) presenting with multi-factorial intracranial bleeding. There was no specific injury pattern involving the cranial vault or cervical spine. Of the patients presenting with a significant injury, facial bones were the most common injury site (84% (n = 54)). The most common site of facial fractures was the nasal bones followed by dental trauma and maxillary fractures.

Conclusion

This single-centre, retrospective observational study has shown no reduction in serious head, neck and facial injuries. Large-scale, multicentre studies will need to be undertaken to understand the true impact of legislative change.

导言本研究的目的是探讨在不考虑其他因素的情况下，为电动滑板车（E-Scooter）提供更安全骑行条件的立法改革是否会对减少重大头部、面部和颈部创伤产生影响。此外，还要确定因电动滑板车事故初次到急诊科（ED）就诊的患者的头部、面部和颈部放射损伤模式：在一个大都市的三级急诊室对电动滑板车事故后的患者进行回顾性单中心观察研究，比较立法修改前后 6 个月的情况：结果：443名患者在电动摩托车事故后就诊：191名患者在立法修改前6个月就诊，252名患者在立法修改后6个月就诊。立法修改前和立法修改后分别有 162 名和 217 名患者进行了阴性 CT 检查。立法修改前和立法修改后分别有 29 名和 35 名患者的 CT 检查显示头部、面部或颈部有明显创伤。最常见的颅内出血类型是蛛网膜下腔出血，其次是硬膜下腔出血，有相当一部分患者（41%）表现为多因素颅内出血。颅顶或颈椎没有特殊的损伤模式。在出现明显损伤的患者中，面部骨骼是最常见的损伤部位（84%（n = 54））。面部骨折最常见的部位是鼻骨，其次是牙齿外伤和上颌骨骨折：这项单中心回顾性观察研究表明，严重的头颈部和面部损伤并没有减少。要了解立法改革的真正影响，还需要进行大规模的多中心研究。

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引用次数: 0

IRSA ASM 2024 Abstract 摘要

IF 2.2 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Medical Imaging and Radiation Oncology

Pub Date : 2024-10-07 DOI: 10.1111/1754-9485.13759

引用次数: 0

Are histomorphological patterns a predictor for survival in uveal melanoma patients with hepatic metastases undergoing hepatic artery infusion chemotherapy? 组织形态学模式能否预测接受肝动脉输注化疗的肝转移葡萄膜黑色素瘤患者的生存率？

IF 2.2 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Medical Imaging and Radiation Oncology

Pub Date : 2024-09-24 DOI: 10.1111/1754-9485.13783

Hannah L Steinberg-Vorhoff, Saskia C Ting, Sebastian Zensen, Johannes M Ludwig, Yan Li, Heike Richly, Johannes Grüneisen, Jens T Siveke, Jens M Theysohn, Benedikt M Schaarschmidt

Introduction

In uveal melanoma (UM) patients with hepatic metastases, hepatic artery infusion chemotherapy (HAIC) is a viable, palliative treatment option. To evaluate the impact of two histomorphological patterns (spindle cell vs. epithelioid) of liver metastases on median overall survival (mOS) in UM patients undergoing HAIC.

Methods

A retrospective analysis with 60 UM patients (29 females, mean age: 61.6 ± 12.1 years) with hepatic metastases was performed. Histomorphological patterns in metastases were analysed and classified as either predominant spindle cell or epithelioid pattern. mOS between both patient groups was analysed using Kaplan–Meier curves and the log-rank test.

Results

In 73.3% (44/60) of the metastases, a predominant epithelioid pattern, in 21.7% (13/60) a predominant spindle cell pattern, and in 5% (3/60) other patterns were found. No significant differences between patients with an epithelioid (mOS: 14.2 months, 95% CI: 8.8–19.6) and a spindle cell pattern (mOS: 14.4 months, 95% CI: 4.3–24.5) were detected by the log-rank test, χ²(2) = 0.22, P = 0.881.

Conclusion

Histomorphological patterns of UM metastases do not seem to be a predictor for mOS in UM patients undergoing HAIC.

简介：对于有肝转移的葡萄膜黑色素瘤（UM）患者，肝动脉灌注化疗（HAIC）是一种可行的姑息治疗方案。目的是评估两种组织形态学模式（纺锤形细胞与上皮样）的肝转移对接受HAIC治疗的UM患者中位总生存期（mOS）的影响：方法：对60例有肝转移的子宫内膜癌患者（29例女性，平均年龄：61.6 ± 12.1岁）进行回顾性分析。采用卡普兰-梅耶曲线和对数秩检验对两组患者的 mOS 进行分析：73.3%（44/60）的转移灶以上皮样形态为主，21.7%（13/60）的转移灶以纺锤形细胞形态为主，5%（3/60）的转移灶以其他形态为主。上皮样（mOS：14.2 个月，95% CI：8.8-19.6）和纺锤形细胞样（mOS：14.4 个月，95% CI：4.3-24.5）患者之间无明显差异，经对数秩检验，χ2(2) = 0.22，P = 0.881：UM转移灶的组织形态学模式似乎并不能预测接受HAIC治疗的UM患者的mOS。

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引用次数: 0

Demystifying the challenging diagnosis of post-radiation nasopharyngeal necrosis on multimodality imaging 揭开多模态成像对放疗后鼻咽坏死诊断的神秘面纱。

IF 2.2 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Medical Imaging and Radiation Oncology

Pub Date : 2024-09-24 DOI: 10.1111/1754-9485.13784

Kwok Yan Li, Hoi Ming Kwok, Wah Cheuk, Ka Fai Johnny Ma

Post-radiation nasopharyngeal necrosis (PRNN) is a rare but life-threatening condition that often poses a diagnostic challenge in imaging studies owing to its overlapping features with recurrent nasopharyngeal tumours. We herein describe the characteristic imaging appearance of PRNN on post-contrast T1-weighted magnetic resonance imaging, diffusion-weighted imaging (DWI) and fluorodeoxyglucose (FDG)-PET/CT which may provide insights into its pathological findings.

放疗后鼻咽坏死（PRNN）是一种罕见但危及生命的疾病，由于其特征与复发性鼻咽肿瘤重叠，往往给影像学诊断带来挑战。我们在此描述了 PRNN 在对比后 T1 加权磁共振成像、弥散加权成像（DWI）和氟脱氧葡萄糖（FDG）-PET/CT 上的特征性成像表现，这可能有助于了解其病理结果。

引用次数: 0

A cross-sectional study assessing the role of interventional radiology services in regional and remote Australia 一项横断面研究，评估介入放射学服务在澳大利亚地区和偏远地区的作用。

IF 2.2 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Medical Imaging and Radiation Oncology

Pub Date : 2024-09-23 DOI: 10.1111/1754-9485.13782

Warren Clements, Adil Zia, Kelvin Chang, Nicholas Brown, Jim Koukounaras, Tim Joseph, Matthew W Lukies, Tuan Phan, Gerard S Goh, Dinesh Varma, Heath Tomlinson, Mark Bolger, Helen Kavnoudias

Introduction

It is estimated that 8% of hospitalised patients require treatment from Interventional Radiology (IR). However, little is known about the potential impact of IR on regional and remote Australians, including Indigenous patients. This study aimed to assess treatments performed by IRs on regional/remote patients to predict future IR workforce and governance needs.

Methods

Single-centre cross-sectional study at a tertiary Victorian hospital. Patients were identified when they had an advanced IR treatment between 1 January 2022 and 2024. Basic procedures such as biopsy and drain insertion were not included. The primary outcome was the type and volume of IR treatments performed on patients who were transferred from a regional or remote home location for treatment.

Results

Of 3485 advanced IR interventions, 908 procedures (26.0%) from patients who lived in a regional or remote location were included with 36.5% female, of mean age 55.6 years (SD 17.9). 1.4% identified as Indigenous which is similar to the Indigenous population incidence in Victoria of 1.0%. Of this group, 350 (38.5%) were either a day procedure, overnight elective admission, or simple inpatient procedure which could have been performed in a regional centre, which included 1.1% Indigenous patients.

Conclusion

There is an unmet need for IR services in regional and remote Australia, with many patients being transferred to our metropolitan centre for treatment that could be performed in regional IR hubs. This data will be important to drive government and hospital planning including capital infrastructure, workforce modelling and future recognition of IR as a new specialty in Australia.

导言：据估计，8% 的住院病人需要接受介入放射学（IR）治疗。然而，人们对介入放射学对地区和偏远地区澳大利亚人（包括土著患者）的潜在影响知之甚少。本研究旨在评估介入放射科对地区/偏远地区患者进行的治疗，以预测未来介入放射科的劳动力和管理需求：方法：在维多利亚州一家三级医院进行单中心横断面研究。2022年1月1日至2024年1月1日期间，对接受过先进IR治疗的患者进行识别。不包括活检和插入引流管等基本程序。主要结果是对从地区或偏远家庭所在地转院接受治疗的患者进行红外治疗的类型和数量：在 3485 例先进红外介入治疗中，有 908 例（26.0%）来自地区或偏远地区的患者，其中女性占 36.5%，平均年龄 55.6 岁（SD 17.9）。1.4%的患者被认定为土著居民，这与维多利亚州土著居民的发病率1.0%相似。在这组患者中，有350人（38.5%）是日间手术、过夜择期入院或简单的住院手术，这些手术本可以在地区中心进行，其中包括1.1%的土著患者：结论：澳大利亚地区和偏远地区对红外服务的需求尚未得到满足，许多病人被转到我们的都市中心接受治疗，而这些治疗本可以在地区红外中心进行。这些数据对于推动政府和医院的规划（包括资本基础设施、劳动力建模以及未来将红外成像作为澳大利亚的一个新专科）非常重要。

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引用次数: 0

Research productivity of RANZCR radiation oncology trainees from 2014 to 2023 2014 年至 2023 年 RANZCR 放射肿瘤学受训人员的研究生产率。

IF 2.2 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Medical Imaging and Radiation Oncology

Pub Date : 2024-09-20 DOI: 10.1111/1754-9485.13752

Emma Jane Quinn, Daniel Roos, Melissa James, Sweet Ping Ng, Frank Saran, Sashendra Senthi, Yu Yang Soon, Wee Loon Ong

Introduction

The aim of this study was to describe the research productivity among RANZCR Radiation Oncology (RO) trainees.

Methods

Publicly available data on RO fellows, who were awarded the RANZCR fellowship between July 2014 and June 2023, was extracted from the RANZCR Annual Reports. Fellows who had qualified overseas and did not undertake full RANZCR training were excluded. A PubMed search was performed for publications by each fellow in the 5 years prior, and 6 months, after the estimated completion of training. Research productivity was defined as the number of first-author and any-author publications per trainee.

Results

In total, 168 eligible RO fellows were included in this study. 104 (62%) and 118 (70%) fellows had first-author and any-author publications during training, respectively. A total of 203 first-author and 308 unique any-author publications were identified, with mean first-author and any-author publications per trainee of 1.21 (SD = 2.37) and 2.02 (SD = 3.71), respectively. Trainee research was most commonly published in JMIRO (34% of first-author and 27% of any-author publications). There were significant differences in the number of first-author publications by gender (P = 0.04) and training jurisdictions (P = 0.03). There were also differences in the number of any-author publications by gender (P = 0.002) and training jurisdictions (P = 0.03). There was a significant increase in any-author publications over the 9-year study period (P = 0.005).

Conclusion

This is the first study evaluating research productivity among RO fellows during training. We identified disparities in research productivity by gender and training jurisdictions. This offers opportunities to tailor efforts to better support a vibrant and productive research culture across the RO training program.

导言：本研究旨在描述新西兰放射肿瘤研究所（RANZCR）受训人员的研究效率：从RANZCR年度报告中提取了2014年7月至2023年6月期间获得RANZCR研究员资格的RO研究员的公开数据。不包括在海外获得资格且未接受完整RANZCR培训的研究员。我们在 PubMed 上搜索了每位研究员在预计完成培训之前 5 年和之后 6 个月内发表的论文。研究效率被定义为每位受训人员发表的第一作者和任何作者的论文数量：本研究共纳入了 168 名符合条件的 RO 研究员。104名（62%）和118名（70%）学员在培训期间分别发表了第一作者和任何作者的论文。共有203篇第一作者论文和308篇任何作者论文被确认，每位学员发表的第一作者和任何作者论文的平均数量分别为1.21篇（标准差=2.37）和2.02篇（标准差=3.71）。受训人员的研究成果最常发表在《JMIRO》上（占第一作者论文的 34%，占任何作者论文的 27%）。第一作者发表论文的数量在性别（P = 0.04）和培训辖区（P = 0.03）方面存在明显差异。不同性别（P = 0.002）和培训辖区（P = 0.03）的任何作者发表的论文数量也存在差异。在 9 年的研究期间，任何作者发表的论文数量都有明显增加（P = 0.005）：这是第一项对区域研究员在培训期间的研究效率进行评估的研究。我们发现了不同性别和培训辖区的研究生产率差异。这为调整工作提供了机会，以更好地支持整个研究员培训计划中充满活力和富有成效的研究文化。

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引用次数: 0

Overview of cardiac toxicity from radiation therapy 放疗的心脏毒性概述。

IF 2.2 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Medical Imaging and Radiation Oncology

Pub Date : 2024-09-20 DOI: 10.1111/1754-9485.13757

Vicky Chin, Robert N Finnegan, Paul Keall, James Otton, Geoff P Delaney, Shalini K Vinod

Radiotherapy is an essential part of treatment for many patients with thoracic cancers. However, proximity of the heart to tumour targets can lead to cardiac side effects, with studies demonstrating link between cardiac radiation dose and adverse outcomes. Although reducing cardiac dose can reduce associated risks, most cardiac constraint recommendations in clinical use are generally based on dose to the whole heart, as dose assessment at cardiac substructure levels on individual patients has been limited historically. Furthermore, estimation of an individual's cardiac risk is complex and multifactorial, which includes radiation dose alongside baseline risk factors, and the impact of systemic therapies. This review gives an overview of the epidemiological impact of cancer and cardiac disease, risk factors contributing to radiation-related cardiotoxicity, the evidence for cardiac side effects and future directions in cardiotoxicity research. A better understanding of the interactions between risk factors, balancing treatment benefit versus toxicity and the ongoing management of cardiac risk is essential for optimal clinical care. The emerging field of cardio-oncology is thus a multidisciplinary collaborative effort to enable better understanding of cardiac risks and outcomes for better-informed patient management decisions.

放疗是许多胸部癌症患者治疗的重要组成部分。然而，心脏靠近肿瘤靶点可能会导致心脏副作用，有研究表明心脏放射剂量与不良后果之间存在联系。虽然减少心脏剂量可以降低相关风险，但临床上使用的大多数心脏限制建议一般都是基于整个心脏的剂量，因为对单个患者心脏亚结构水平的剂量评估历来有限。此外，对个体心脏风险的评估是复杂的、多因素的，其中包括辐射剂量、基线风险因素和系统疗法的影响。本综述概述了癌症和心脏病的流行病学影响、导致辐射相关心脏毒性的风险因素、心脏副作用的证据以及心脏毒性研究的未来方向。更好地了解风险因素之间的相互作用、平衡治疗效益与毒性以及持续管理心脏风险对于优化临床治疗至关重要。因此，新兴的心脏肿瘤学领域是一个多学科合作的领域，目的是更好地了解心脏风险和结果，从而做出更明智的患者管理决策。

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引用次数: 0

Incidental findings in research brain MRI: Definition, prevalence and ethical implications 脑磁共振成像研究中的意外发现：定义、发生率和伦理意义。

IF 2.2 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Medical Imaging and Radiation Oncology

Pub Date : 2024-09-20 DOI: 10.1111/1754-9485.13744

Kenneth J de Jong, Emma Poon, Michelle Foo, Julian Maingard, Hong Kuan Kok, Christen Barras, Anousha Yazdabadi, Benham Shaygi, Gregory J Fitt, Gary Egan, Mark Brooks, Hamed Asadi

Radiological incidental findings (IFs) are previously undetected abnormalities which are unrelated to the original indication for imaging and are unexpectedly discovered. In brain magnetic resonance imaging (MRI), the prevalence of IFs is increasing. By reviewing the literature on IFs in brain MRI performed for research purposes and discussing ethical considerations of IFs, this paper provides an overview of brain IF research results and factors contributing to inconsistencies and considers how the consent process can be improved from an ethical perspective. We found that despite extensive literature regarding IFs in research MRI of the brain, there are major inconsistencies in the reported prevalence, ranging from 1.3% to 99%. Many factors appear to contribute to this broad range: lack of standardised definition, participant demographics variance, heterogenous MRI scanner strength and sequences, reporter variation and results classification. We also found significant discrepancies in the review, consent and clinical communication processes pertaining to the ethical nature of these studies. These findings have implications for future studies, particularly those involving artificial intelligence. Further research, particularly in relation to MRI brain IFs would be useful to explore the generalisability of study results.

放射学意外发现（IFs）是指以前未发现的异常情况，这些异常情况与最初的成像适应症无关，而且是意外发现的。在脑磁共振成像（MRI）中，IFs 的发生率越来越高。通过回顾以研究为目的的脑磁共振成像中 IFs 的相关文献并讨论 IFs 的伦理因素，本文概述了脑 IF 的研究结果和导致不一致的因素，并从伦理角度探讨了如何改进同意程序。我们发现，尽管有大量文献涉及脑部核磁共振成像研究中的 IFs，但报告的发生率存在很大的不一致，从 1.3% 到 99% 不等。造成这一广泛范围的因素似乎有很多：缺乏标准化定义、参与者人口统计学差异、不同的 MRI 扫描仪强度和序列、报告者差异和结果分类。我们还发现，在与这些研究的伦理性质相关的审查、同意和临床沟通过程中存在重大差异。这些发现对未来的研究，尤其是涉及人工智能的研究具有启示意义。进一步的研究，尤其是与核磁共振成像脑中频有关的研究，将有助于探索研究结果的普遍性。

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引用次数: 0