首页 > 最新文献

Journal of Mahatma Gandhi University of Medical Sciences and Technology最新文献

英文 中文
A Rare Case Report of Out of the Ordinary Canal of Nuck Hernia Encompassing Pelvic Structures, Showing up as a Labial Mass 罕见的异常管颈疝包围盆腔结构,表现为唇肿块一例报告
Pub Date : 2021-08-31 DOI: 10.5005/jp-journals-10057-0147
Neha Bagri, R. Misra
Aim and objective: We report a rare case of the canal of Nuck hernia containing part of the uterus and both ovaries as its contents. The aim is to build up the awareness of this condition by reviewing the ultrasound and MRI imaging findings and identification of prolapsed ovary with correct knowledge of the entity and focused analysis. Background: The patent canal of Nuck is one of the rare developmental entities in females. Hernia of the canal of Nuck is an extension of the peritoneal fold through the inguinal canal up to the labia majora. Defective obliteration of this peritoneal fold leads to herniation of abdominal content into the inguinal canal. Case description: An exceptionally rare case of a 5-month-old female child who presented to us with a palpable, non-tender, left labial mass. Ultrasound and MRI were performed showing the contents of herniating sac as uterine fundus and bilateral ovaries along with minimal free fluid. The infant was managed conservatively and kept under follow-up. Conclusion: Incidence of both ovary and uterus as contents of hernia is very rare. Furthermore, early and correct identification of the herniated ovary prevents an uncalled-for surgery. Clinical significance: It is very important to be familiar with this entity, especially in cases of ovarian hernia due to the risk of associated complications like incarceration and torsion.
目的和目的:我们报告一例罕见的喉疝管包含部分子宫和两个卵巢作为其内容物。目的是通过回顾卵巢脱垂的超声和MRI成像结果,以及对卵巢脱垂的正确认识和重点分析,建立对这种情况的认识。背景:努克未闭管是女性罕见的发育实体之一。努克疝是腹膜褶皱的延伸,通过腹股沟管向上延伸至大阴唇。腹膜褶皱的不完全性闭塞导致腹膜内容物疝入腹股沟管。病例描述:一个非常罕见的病例,一个5个月大的女婴谁提出了一个可触及的,无压痛,左唇肿块。超声和MRI显示疝囊内容物为子宫底和双侧卵巢,并有少量游离液。对患儿进行保守治疗并随访。结论:卵巢和子宫同时作为疝内容物的发生率非常低。此外,卵巢疝的早期和正确的识别可以防止不必要的手术。临床意义:熟悉这个实体是非常重要的,特别是在卵巢疝的情况下,由于相关并发症的风险,如嵌顿和扭转。
{"title":"A Rare Case Report of Out of the Ordinary Canal of Nuck Hernia Encompassing Pelvic Structures, Showing up as a Labial Mass","authors":"Neha Bagri, R. Misra","doi":"10.5005/jp-journals-10057-0147","DOIUrl":"https://doi.org/10.5005/jp-journals-10057-0147","url":null,"abstract":"Aim and objective: We report a rare case of the canal of Nuck hernia containing part of the uterus and both ovaries as its contents. The aim is to build up the awareness of this condition by reviewing the ultrasound and MRI imaging findings and identification of prolapsed ovary with correct knowledge of the entity and focused analysis. Background: The patent canal of Nuck is one of the rare developmental entities in females. Hernia of the canal of Nuck is an extension of the peritoneal fold through the inguinal canal up to the labia majora. Defective obliteration of this peritoneal fold leads to herniation of abdominal content into the inguinal canal. Case description: An exceptionally rare case of a 5-month-old female child who presented to us with a palpable, non-tender, left labial mass. Ultrasound and MRI were performed showing the contents of herniating sac as uterine fundus and bilateral ovaries along with minimal free fluid. The infant was managed conservatively and kept under follow-up. Conclusion: Incidence of both ovary and uterus as contents of hernia is very rare. Furthermore, early and correct identification of the herniated ovary prevents an uncalled-for surgery. Clinical significance: It is very important to be familiar with this entity, especially in cases of ovarian hernia due to the risk of associated complications like incarceration and torsion.","PeriodicalId":16223,"journal":{"name":"Journal of Mahatma Gandhi University of Medical Sciences and Technology","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83784658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breast Cancer Tumor Biology Characteristics and Its Correlation in a Tertiary Care Center 三级保健中心乳腺癌肿瘤生物学特征及其相关性研究
Pub Date : 2021-08-31 DOI: 10.5005/jp-journals-10057-0143
J. Sharma, Tapan Kapoor, Guman Singh, A. Loyal, D. Singh
Ab s t r Ac t Aims/Objectives: The study aims to evaluate and correlate the relationship between hormone receptor status—estrogen, progesterone receptor (ER and PR), and Herceptin receptor (Her-2/neu) with tumor characteristics in breast cancer patients. Materials and methods: The current study included 101 breast cancer patients of various age-groups from the period 2016–2020. The tumors were evaluated for hormone expression, size, histologic grade, lymphovascular invasion, and axillary node status. The excised breast tissue specimen was evaluated for hormone status by immunohistochemistry (IHC) testing on paraffin blocks and was further analyzed using the fluorescence in situ hybridization (FISH) technique as per requirement. Stratification based on hormone receptor status was done in four categories—ER+PR+Her-2neu−, ER−PR−Her-2neu+, ER+PR+Her-2neu+, and ER−PR−Her-2neu−. Results: In this study, 37.6% of tumors were ER+PR+Her-2neu−, 13.8% ER−PR−Her-2neu+, 13.8% ER+PR+Her-2neu+, and 34.6% ER−PR−Her2neu−. Among high-grade tumors, more than half (52%) patients were hormone receptor-negative, whereas among low-grade tumors 55% of patients were hormone receptor-positive. Sixteen percent of patients presented with a younger age-group (<35 years) and in these patients, nearly 38% were Her-2/neu positive and most of the Her-2/neu receptor-positive patients (80%) had lymphovascular space invasion. Primary tumor size at time of presentation was <2 cm (T1) in only 11% of cases and 2–5 cm (T2) in 72% of cases. Lymph node positivity did not correlate with hormone receptor status. Conclusion: The incidence of Her2-neu positive breast cancer patients was higher in the Indian population as compared to the Western world. The current study depicts the distinct shift in terms of tumor stage and biology, higher rate of Her-2/neu-positivity, younger age at diagnosis, larger tumor size, advanced tumor grade, and more positive lymph node involvement in contrast to the Western population.
目的/目的:本研究旨在评价乳腺癌患者激素受体状态——雌激素、孕激素受体(ER和PR)、赫赛汀受体(Her-2/neu)与肿瘤特征的关系,并探讨其相关性。材料与方法:本研究纳入了2016-2020年期间101例不同年龄段的乳腺癌患者。评估肿瘤的激素表达、大小、组织学分级、淋巴血管浸润和腋窝淋巴结状态。切除乳腺组织标本石蜡块免疫组化(IHC)检测激素状态,并按要求采用荧光原位杂交(FISH)技术进一步分析。基于激素受体状态的分层分为四类:ER+PR+Her-2neu -, ER - PR - Her-2neu+, ER+PR+Her-2neu+和ER - PR - Her-2neu -。结果:本组肿瘤中ER+PR+Her-2neu−占37.6%,ER - PR - Her-2neu+占13.8%,ER+PR+Her-2neu+占13.8%,ER - PR - Her2neu−占34.6%。高档肿瘤中,一半以上(52%)患者激素受体阴性,而低级的肿瘤中55%的患者激素受体阳性。16%的患者出现在较年轻的年龄组(<35岁),在这些患者中,近38%的Her-2/neu阳性,大多数Her-2/neu受体阳性的患者(80%)有淋巴血管间隙浸润。原发肿瘤大小在演讲时间< 2厘米(T1)只有11%的情况下,2 - 5厘米(T2)在72%的情况下。淋巴结阳性与激素受体状态无关。结论:与西方国家相比,印度人群中Her2-neu阳性乳腺癌患者的发病率更高。当前的研究描述了不同的转移肿瘤阶段和生物学而言,更高的her - 2 / neu-positivity,年轻在诊断、较大的肿瘤大小,淋巴结先进肿瘤品位,更积极与西方人口。
{"title":"Breast Cancer Tumor Biology Characteristics and Its Correlation in a Tertiary Care Center","authors":"J. Sharma, Tapan Kapoor, Guman Singh, A. Loyal, D. Singh","doi":"10.5005/jp-journals-10057-0143","DOIUrl":"https://doi.org/10.5005/jp-journals-10057-0143","url":null,"abstract":"Ab s t r Ac t Aims/Objectives: The study aims to evaluate and correlate the relationship between hormone receptor status—estrogen, progesterone receptor (ER and PR), and Herceptin receptor (Her-2/neu) with tumor characteristics in breast cancer patients. Materials and methods: The current study included 101 breast cancer patients of various age-groups from the period 2016–2020. The tumors were evaluated for hormone expression, size, histologic grade, lymphovascular invasion, and axillary node status. The excised breast tissue specimen was evaluated for hormone status by immunohistochemistry (IHC) testing on paraffin blocks and was further analyzed using the fluorescence in situ hybridization (FISH) technique as per requirement. Stratification based on hormone receptor status was done in four categories—ER+PR+Her-2neu−, ER−PR−Her-2neu+, ER+PR+Her-2neu+, and ER−PR−Her-2neu−. Results: In this study, 37.6% of tumors were ER+PR+Her-2neu−, 13.8% ER−PR−Her-2neu+, 13.8% ER+PR+Her-2neu+, and 34.6% ER−PR−Her2neu−. Among high-grade tumors, more than half (52%) patients were hormone receptor-negative, whereas among low-grade tumors 55% of patients were hormone receptor-positive. Sixteen percent of patients presented with a younger age-group (<35 years) and in these patients, nearly 38% were Her-2/neu positive and most of the Her-2/neu receptor-positive patients (80%) had lymphovascular space invasion. Primary tumor size at time of presentation was <2 cm (T1) in only 11% of cases and 2–5 cm (T2) in 72% of cases. Lymph node positivity did not correlate with hormone receptor status. Conclusion: The incidence of Her2-neu positive breast cancer patients was higher in the Indian population as compared to the Western world. The current study depicts the distinct shift in terms of tumor stage and biology, higher rate of Her-2/neu-positivity, younger age at diagnosis, larger tumor size, advanced tumor grade, and more positive lymph node involvement in contrast to the Western population.","PeriodicalId":16223,"journal":{"name":"Journal of Mahatma Gandhi University of Medical Sciences and Technology","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86354628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of OHVIRA Syndrome with Urethral Stenosis OHVIRA综合征合并尿道狭窄1例
Pub Date : 2021-08-31 DOI: 10.5005/jp-journals-10057-0158
Ketul R Patel, N. Sadasukhi, T. Sadasukhi, M. Gupta, H. Gupta, Ashish Sharma, Sandeep Malik
A bstrAct Obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) is a rare anomaly of the urogenital system. The characteristic triad of this syndrome, which was initially reported in 1950, is didelphys uterus, obstructed hemivagina, and ipsilateral renal agenesis (Embrey 1 ). The prevalence of congenital Müllerian duct anomalies is reported to be 1%. 2 A 24-year-old girl got admission to MGH on 15.3.2019 with lower abdominal pain and difficulty in the passing of urine. Her menarche was established 6 months back with a regular cycle and associated with dysmenorrhea. Magnetic resonance imaging (MRI) established the diagnosis of OHVIRA. She underwent surgery for drainage of the hematocolpos and excision of the vaginal septum and urethral dilatation with cystoscopy followed by an uncomplicated recovery and the patient had normal menstrual cycles after surgery.
梗阻性半阴道伴同侧肾异常(OHVIRA)是一种罕见的泌尿生殖系统异常。该综合征的特征性三联征最初于1950年报道,为子宫双陷、半阴道梗阻和同侧肾发育不全(Embrey 1)。据报道,先天性勒管异常的发生率为1%。2一名24岁女孩于2019年3月15日因下腹疼痛、排尿困难入院。6个月前开始月经初潮,月经周期正常,伴有痛经。磁共振成像(MRI)确立了OHVIRA的诊断。她接受了直肠引流术、阴道间隔切除术和膀胱镜下尿道扩张术,术后恢复顺利,月经周期正常。
{"title":"A Rare Case of OHVIRA Syndrome with Urethral Stenosis","authors":"Ketul R Patel, N. Sadasukhi, T. Sadasukhi, M. Gupta, H. Gupta, Ashish Sharma, Sandeep Malik","doi":"10.5005/jp-journals-10057-0158","DOIUrl":"https://doi.org/10.5005/jp-journals-10057-0158","url":null,"abstract":"A bstrAct Obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) is a rare anomaly of the urogenital system. The characteristic triad of this syndrome, which was initially reported in 1950, is didelphys uterus, obstructed hemivagina, and ipsilateral renal agenesis (Embrey 1 ). The prevalence of congenital Müllerian duct anomalies is reported to be 1%. 2 A 24-year-old girl got admission to MGH on 15.3.2019 with lower abdominal pain and difficulty in the passing of urine. Her menarche was established 6 months back with a regular cycle and associated with dysmenorrhea. Magnetic resonance imaging (MRI) established the diagnosis of OHVIRA. She underwent surgery for drainage of the hematocolpos and excision of the vaginal septum and urethral dilatation with cystoscopy followed by an uncomplicated recovery and the patient had normal menstrual cycles after surgery.","PeriodicalId":16223,"journal":{"name":"Journal of Mahatma Gandhi University of Medical Sciences and Technology","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81072184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Natal Teeth in Association with Sublingual Ulceration: A Case Report 出生牙与舌下溃疡:1例报告
Pub Date : 2021-08-31 DOI: 10.5005/jp-journals-10057-0150
Shantanu Jain, Renuka P Chinchalkar, Shavan K Yadav, P. Yadav, P. Lekhwani, N. Gupta
Natal teeth are a rare sight in a newborn child’s oral cavity. The presence of teeth natal teeth can cause a series of damage to the child including difficulty in feeding, ulceration on the tongue. A 31-day-old baby reported to the Department of Pediatric and Preventive Dentistry with a chief complaint of ulceration on the tongue and difficulty in breastfeeding. On further examination, a diagnosis of natal teeth was narrowed down. Due to the presence of mobility of the present teeth and ulceration on the tongue, the teeth were extracted.
在新生儿的口腔中,出生牙是一种罕见的景象。生牙的存在会对孩子造成一系列的伤害,包括进食困难、舌头溃疡。一个31天大的婴儿报告到儿科和预防牙科部,主要抱怨舌头溃疡和母乳喂养困难。进一步检查后,诊断的范围缩小了。由于目前的牙齿存在活动和溃疡的舌头,牙齿被拔除。
{"title":"Natal Teeth in Association with Sublingual Ulceration: A Case Report","authors":"Shantanu Jain, Renuka P Chinchalkar, Shavan K Yadav, P. Yadav, P. Lekhwani, N. Gupta","doi":"10.5005/jp-journals-10057-0150","DOIUrl":"https://doi.org/10.5005/jp-journals-10057-0150","url":null,"abstract":"Natal teeth are a rare sight in a newborn child’s oral cavity. The presence of teeth natal teeth can cause a series of damage to the child including difficulty in feeding, ulceration on the tongue. A 31-day-old baby reported to the Department of Pediatric and Preventive Dentistry with a chief complaint of ulceration on the tongue and difficulty in breastfeeding. On further examination, a diagnosis of natal teeth was narrowed down. Due to the presence of mobility of the present teeth and ulceration on the tongue, the teeth were extracted.","PeriodicalId":16223,"journal":{"name":"Journal of Mahatma Gandhi University of Medical Sciences and Technology","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77909411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
To Study the Prevalence of Vitamin B12 Deficiency among Patients with Hypothyroidism 探讨甲状腺功能减退患者维生素B12缺乏症的患病率
Pub Date : 2021-08-31 DOI: 10.5005/jp-journals-10057-0154
D. Gupta, G. Saxena, O. Choudhary, Anchin Kalia, R. Jat, Manjeet Lnu
{"title":"To Study the Prevalence of Vitamin B12 Deficiency among Patients with Hypothyroidism","authors":"D. Gupta, G. Saxena, O. Choudhary, Anchin Kalia, R. Jat, Manjeet Lnu","doi":"10.5005/jp-journals-10057-0154","DOIUrl":"https://doi.org/10.5005/jp-journals-10057-0154","url":null,"abstract":"","PeriodicalId":16223,"journal":{"name":"Journal of Mahatma Gandhi University of Medical Sciences and Technology","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84060891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Diabetes Mellitus as a Bad Prognostic Marker in COVID-19 Patients and Its Relationship with Inflammatory Markers (CRP, D-dimer, LDH, and Ferritin) 糖尿病作为COVID-19患者不良预后标志物及其与炎症标志物(CRP、d -二聚体、LDH、铁蛋白)的关系
Pub Date : 2021-08-31 DOI: 10.5005/jp-journals-10057-0156
Mukesh Jain, P. Rijhwani, Kishore Moolrajani, Aviral Gupta, Anchin Kalia, C. Mittal, S. Choudhary, Aakriti Vij
Ab s t r Ac t Background: Coronavirus disease 2019 (COVID-19) is a newly recognized illness that is spreading rapidly around the world, causing many disabilities and deaths. Some diseases, for instance, diabetes, are continuously suggested as a risk factor, which contribute to the severity and mortality of COVID-19. However, to date, there are no comprehensive studies done that are aimed at explaining the exact relationship between diabetes mellitus and COVID-19. Thus, this study aims to evaluate the relationship between diabetes and COVID-19 and its relationship with inflammatory markers. Materials and methods: This single-center retrospective observational study was conducted on 187 patients diagnosed with COVID-19. The data were collected on admission or during hospitalization by the attending physicians and was documented in the form of electronic medical records. The need for informed consent from patients was waived due to the time constraints during the COVID-19 emergency. Results: Of the 187 hospitalized patients with COVID-19, 50 patients had diabetes. The median age was 59 years and 35 (70.00%) were male. Common symptoms among all patients included fever (57.21%) and cough (48.13%). Patients with diabetes had a non-significantly higher LDH, ferritin, CRP, and D-dimer when compared with those without diabetes. Coronavirus disease 2019 patients with diabetes were significantly more likely to develop severe disease or suffer mortality, indicating a poorer prognosis among COVID-19 patients. Conclusion: We concluded that diabetes mellitus is associated with greater disease severity and poor outcome (mortality) in COVID-19, and a higher but statistically non-significant inflammatory burden.
背景:2019冠状病毒病(COVID-19)是一种新发现的疾病,正在全球迅速传播,造成许多残疾和死亡。一些疾病,如糖尿病,一直被认为是导致COVID-19严重程度和死亡率的风险因素。然而,迄今为止,还没有全面的研究旨在解释糖尿病和COVID-19之间的确切关系。因此,本研究旨在评估糖尿病与COVID-19的关系及其与炎症标志物的关系。材料与方法:对187例确诊为COVID-19的患者进行单中心回顾性观察性研究。数据由主治医生在入院时或住院期间收集,并以电子病历的形式记录下来。由于COVID-19紧急情况期间的时间限制,无需获得患者的知情同意。结果:187例新冠肺炎住院患者中有50例合并糖尿病。中位年龄59岁,男性35例(70.00%)。常见症状为发热(57.21%)和咳嗽(48.13%)。与没有糖尿病的患者相比,糖尿病患者的LDH、铁蛋白、CRP和d -二聚体没有明显升高。2019冠状病毒病糖尿病患者发生严重疾病或死亡的可能性明显更高,这表明2019冠状病毒病患者的预后较差。结论:我们得出的结论是,糖尿病与COVID-19患者更高的疾病严重程度和较差的预后(死亡率)以及更高但统计学上不显著的炎症负担相关。
{"title":"Diabetes Mellitus as a Bad Prognostic Marker in COVID-19 Patients and Its Relationship with Inflammatory Markers (CRP, D-dimer, LDH, and Ferritin)","authors":"Mukesh Jain, P. Rijhwani, Kishore Moolrajani, Aviral Gupta, Anchin Kalia, C. Mittal, S. Choudhary, Aakriti Vij","doi":"10.5005/jp-journals-10057-0156","DOIUrl":"https://doi.org/10.5005/jp-journals-10057-0156","url":null,"abstract":"Ab s t r Ac t Background: Coronavirus disease 2019 (COVID-19) is a newly recognized illness that is spreading rapidly around the world, causing many disabilities and deaths. Some diseases, for instance, diabetes, are continuously suggested as a risk factor, which contribute to the severity and mortality of COVID-19. However, to date, there are no comprehensive studies done that are aimed at explaining the exact relationship between diabetes mellitus and COVID-19. Thus, this study aims to evaluate the relationship between diabetes and COVID-19 and its relationship with inflammatory markers. Materials and methods: This single-center retrospective observational study was conducted on 187 patients diagnosed with COVID-19. The data were collected on admission or during hospitalization by the attending physicians and was documented in the form of electronic medical records. The need for informed consent from patients was waived due to the time constraints during the COVID-19 emergency. Results: Of the 187 hospitalized patients with COVID-19, 50 patients had diabetes. The median age was 59 years and 35 (70.00%) were male. Common symptoms among all patients included fever (57.21%) and cough (48.13%). Patients with diabetes had a non-significantly higher LDH, ferritin, CRP, and D-dimer when compared with those without diabetes. Coronavirus disease 2019 patients with diabetes were significantly more likely to develop severe disease or suffer mortality, indicating a poorer prognosis among COVID-19 patients. Conclusion: We concluded that diabetes mellitus is associated with greater disease severity and poor outcome (mortality) in COVID-19, and a higher but statistically non-significant inflammatory burden.","PeriodicalId":16223,"journal":{"name":"Journal of Mahatma Gandhi University of Medical Sciences and Technology","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74467370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Triaging for COVID-19 Patients in a Tertiary Care Hospital in West India: A Retrospective Analysis of a Case Series 西印度一家三级医院对COVID-19患者分诊的影响:对一系列病例的回顾性分析
Pub Date : 2021-08-31 DOI: 10.5005/jp-journals-10057-0145
Ashish Jain, P. Rijhwani, S. Jain, Ravi Jain, Anchin Kalia, Pallaavi Goel, Nimish Mathur, Anand B. Jain, Divyansh Gupta
Ab s t r Ac t Introduction: Assessing the clinical severity of coronavirus disease-2019 (COVID-19) and triaging to appropriate levels of care is certainly one of the key elements in the success of managing COVID-19 patients. During the concluded wave of the pandemic, cases were categorized and cared for with set criteria prescribed by authorities. Other triaging criteria were included in contemporary international guidelines, but this hypothesis was never tested if anyone set is ever better than the other. Materials and methods: This is a case series of 165 deceased patients of COVID-19. All patients were categorized as per clinical disease severity and admitted to the designated care area after confirmation of SARS-CoV-2 infection as decided by the admitting doctors. We collected retrospective data from patient medical records and analyzed for medical history, comorbidity profiles, hematology investigations, organ function tests, computed tomography of the thorax, and point-of-care biomarker test (D-dimer, procalcitonin, NT-proBNP, Trop-T). These data were analyzed to compare the differences between the variables of ward and ICU patients by using XLstat software. Results: In this analysis of deceased patients’ case series, we found that there was no significant difference among the patients admitted to ward and ICU for initial demographic and biomarker variables and risk factors. Diabetes was the most commonly found comorbidity. The mortality rate among the ward and ICU (5.89 vs 6.67%, p value: 0.44) was also similar among both the cohorts. Conclusion: In this case series, we could conclude that both the cohorts were comparable at admission on demographic and laboratory parameter profile. Clinical significance: This analysis led us to the conclusion that our existing “triage criteria” for COVID-19 patients will need appropriate modification before the second wave sets in the region.
导言:评估2019冠状病毒病(COVID-19)的临床严重程度并进行适当的护理分级无疑是成功管理COVID-19患者的关键因素之一。在结束的大流行浪潮期间,按照当局规定的既定标准对病例进行了分类和治疗。其他分诊标准也包括在当代国际指南中,但这一假设从未得到检验,是否有哪一套比另一套更好。材料与方法:本研究为165例COVID-19死亡患者的病例系列。所有患者根据临床疾病严重程度进行分类,并在确诊后由入院医生决定进入指定的护理区。我们从患者医疗记录中收集回顾性数据,并分析病史、合并症、血液学调查、器官功能检查、胸部计算机断层扫描和护理点生物标志物检测(d -二聚体、降钙素原、NT-proBNP、Trop-T)。采用XLstat软件对这些数据进行分析,比较病房和ICU患者各变量的差异。结果:在对死亡患者病例系列的分析中,我们发现住院患者和ICU患者在初始人口统计学和生物标志物变量以及危险因素方面没有显著差异。糖尿病是最常见的合并症。病区和ICU的死亡率(5.89 vs 6.67%, p值:0.44)在两个队列中也相似。结论:在这个病例系列中,我们可以得出结论,两个队列在入院时在人口统计学和实验室参数概况方面具有可比性。临床意义:该分析使我们得出结论,在该地区第二波疫情到来之前,我们需要适当修改现有的COVID-19患者“分诊标准”。
{"title":"Impact of Triaging for COVID-19 Patients in a Tertiary Care Hospital in West India: A Retrospective Analysis of a Case Series","authors":"Ashish Jain, P. Rijhwani, S. Jain, Ravi Jain, Anchin Kalia, Pallaavi Goel, Nimish Mathur, Anand B. Jain, Divyansh Gupta","doi":"10.5005/jp-journals-10057-0145","DOIUrl":"https://doi.org/10.5005/jp-journals-10057-0145","url":null,"abstract":"Ab s t r Ac t Introduction: Assessing the clinical severity of coronavirus disease-2019 (COVID-19) and triaging to appropriate levels of care is certainly one of the key elements in the success of managing COVID-19 patients. During the concluded wave of the pandemic, cases were categorized and cared for with set criteria prescribed by authorities. Other triaging criteria were included in contemporary international guidelines, but this hypothesis was never tested if anyone set is ever better than the other. Materials and methods: This is a case series of 165 deceased patients of COVID-19. All patients were categorized as per clinical disease severity and admitted to the designated care area after confirmation of SARS-CoV-2 infection as decided by the admitting doctors. We collected retrospective data from patient medical records and analyzed for medical history, comorbidity profiles, hematology investigations, organ function tests, computed tomography of the thorax, and point-of-care biomarker test (D-dimer, procalcitonin, NT-proBNP, Trop-T). These data were analyzed to compare the differences between the variables of ward and ICU patients by using XLstat software. Results: In this analysis of deceased patients’ case series, we found that there was no significant difference among the patients admitted to ward and ICU for initial demographic and biomarker variables and risk factors. Diabetes was the most commonly found comorbidity. The mortality rate among the ward and ICU (5.89 vs 6.67%, p value: 0.44) was also similar among both the cohorts. Conclusion: In this case series, we could conclude that both the cohorts were comparable at admission on demographic and laboratory parameter profile. Clinical significance: This analysis led us to the conclusion that our existing “triage criteria” for COVID-19 patients will need appropriate modification before the second wave sets in the region.","PeriodicalId":16223,"journal":{"name":"Journal of Mahatma Gandhi University of Medical Sciences and Technology","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84344921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Knowledge and Awareness of School Teachers of Jaipur in Emergency Management of Traumatic Dental Injuries 斋浦尔学校教师在创伤性牙损伤应急管理中的知识和意识
Pub Date : 2021-02-28 DOI: 10.5005/jp-journals-10057-0186
Mili R Meghpara, Yashi Sharma, Bharathi Padiyar
{"title":"Knowledge and Awareness of School Teachers of Jaipur in Emergency Management of Traumatic Dental Injuries","authors":"Mili R Meghpara, Yashi Sharma, Bharathi Padiyar","doi":"10.5005/jp-journals-10057-0186","DOIUrl":"https://doi.org/10.5005/jp-journals-10057-0186","url":null,"abstract":"","PeriodicalId":16223,"journal":{"name":"Journal of Mahatma Gandhi University of Medical Sciences and Technology","volume":"111 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78104223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adaptive Radiotherapy in Locally Advanced Head and Neck Cancers: Impact on Target Volume Shrinkage and Organ at Risk and its Clinical Outcome 局部晚期头颈部肿瘤的适应性放疗:对靶体积缩小和危险器官的影响及其临床结果
Pub Date : 2021-02-28 DOI: 10.5005/jp-journals-10057-0185
Sukhveer Tanwar, Shikha Dhal, S. Goyal
{"title":"Adaptive Radiotherapy in Locally Advanced Head and Neck Cancers: Impact on Target Volume Shrinkage and Organ at Risk and its Clinical Outcome","authors":"Sukhveer Tanwar, Shikha Dhal, S. Goyal","doi":"10.5005/jp-journals-10057-0185","DOIUrl":"https://doi.org/10.5005/jp-journals-10057-0185","url":null,"abstract":"","PeriodicalId":16223,"journal":{"name":"Journal of Mahatma Gandhi University of Medical Sciences and Technology","volume":"69 5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83427910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of a Mutilated Molar Using Custom Cast Post: A Case Report 自定义铸造桩治疗磨牙残缺1例
Pub Date : 2021-02-28 DOI: 10.5005/jp-journals-10057-0182
A. Prasad, Deepak Raisingani, D. Khurana, Asha Jetwani
Tooth number 47 the concerned tooth here was ideally indicated for extraction but the patient was keen to save the tooth, so the treatment plan decided was the rehabilitation of the tooth with custom-designed cast post followed by a metal crown. Informed consent was obtained from the patient. Access cavity was prepared and all caries from the pulp floor were excavated in relation to tooth number 47. Working length was determined using 15K ss hand files (Fig. 2A). Thorough cleaning and shaping was done till size F3 ProTaper files with copious irrigation using 2% chlorhexidine, normal saline, 5% sodium hypochlorite, and then final rinse with saline. Intracanal dressing of calcium hydroxide dressing was placed for 7 days. In the next appointment, obturation was done with F3 ProTaper cones using resin-based sealer (Figs 2B and 3A). While excavating caries during access cavity preparation, a very thin layer of dentin remained as caries were almost involving the furcation. So to reinforce the floor, a layer of MTA was placed on pulpal floor (Fig. 3A) (keeping the canals patent) and on the weakened mesial wall as well. It was then covered with moist cotton followed by placement of a temporary restoration. In the next visit, post space preparation was done in the distal canal with the help of Peeso Reamer up to number 3 (1.1 mm diameter) leaving 5 mm gutta-percha apically (Fig. 3B). GIC was IN T R O D U C T I O N
47号牙齿,也就是这里所涉及的牙齿,理想情况下适合拔牙,但患者急于保住这颗牙齿,所以治疗计划是用定制设计的铸造桩和金属冠修复牙齿。获得患者的知情同意。预备通道腔,并从牙髓底挖出与第47颗牙有关的所有龋。使用15K s手锉确定工作长度(图2A)。用2%氯己定、生理盐水、5%次氯酸钠大量冲洗,彻底清洗定型至F3尺寸ProTaper锉,最后用生理盐水冲洗。管内敷料氢氧化钙敷料放置7天。在下一次预约中,使用树脂基密封剂使用F3 ProTaper椎体进行封闭(图2B和3A)。在预备接入孔的过程中,由于龋几乎累及分叉,在挖掘龋的过程中,牙本质只剩下很薄的一层。因此,为了加固地板,在髓底(图3A)(保持管通畅)和弱化的中侧壁上放置一层MTA。然后用湿棉覆盖,然后进行临时修复。在下一次访问中,在Peeso扩孔器(直径1.1 mm)的帮助下,在远端根管中进行桩位准备,最多3号(直径1.1 mm),顶端留下5 mm的杜胶(图3B)。GIC在纽约,但在纽约
{"title":"Management of a Mutilated Molar Using Custom Cast Post: A Case Report","authors":"A. Prasad, Deepak Raisingani, D. Khurana, Asha Jetwani","doi":"10.5005/jp-journals-10057-0182","DOIUrl":"https://doi.org/10.5005/jp-journals-10057-0182","url":null,"abstract":"Tooth number 47 the concerned tooth here was ideally indicated for extraction but the patient was keen to save the tooth, so the treatment plan decided was the rehabilitation of the tooth with custom-designed cast post followed by a metal crown. Informed consent was obtained from the patient. Access cavity was prepared and all caries from the pulp floor were excavated in relation to tooth number 47. Working length was determined using 15K ss hand files (Fig. 2A). Thorough cleaning and shaping was done till size F3 ProTaper files with copious irrigation using 2% chlorhexidine, normal saline, 5% sodium hypochlorite, and then final rinse with saline. Intracanal dressing of calcium hydroxide dressing was placed for 7 days. In the next appointment, obturation was done with F3 ProTaper cones using resin-based sealer (Figs 2B and 3A). While excavating caries during access cavity preparation, a very thin layer of dentin remained as caries were almost involving the furcation. So to reinforce the floor, a layer of MTA was placed on pulpal floor (Fig. 3A) (keeping the canals patent) and on the weakened mesial wall as well. It was then covered with moist cotton followed by placement of a temporary restoration. In the next visit, post space preparation was done in the distal canal with the help of Peeso Reamer up to number 3 (1.1 mm diameter) leaving 5 mm gutta-percha apically (Fig. 3B). GIC was IN T R O D U C T I O N","PeriodicalId":16223,"journal":{"name":"Journal of Mahatma Gandhi University of Medical Sciences and Technology","volume":"136 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76726990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Mahatma Gandhi University of Medical Sciences and Technology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1