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Preliminary study of the criticality monitoring method based on the simulation for the activity ratio of short half-life noble-gas fission products from fuel debris 基于燃料碎片短半衰期惰性气体裂变产物活度比模拟的临界监测方法初步研究
IF 1.2 4区 工程技术 Q2 NUCLEAR SCIENCE & TECHNOLOGY
Journal of Nuclear Science and Technology
Pub Date : 2024-01-09 DOI: 10.1080/00223131.2023.2300773
E. Riyana, Keisuke Okumura, M. Sakamoto, Taichi Matsumura, Kenichi Terashima, I. Kanno
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引用次数: 0
Analytical studies on effects of wind on dispersion of hydrogen leaked in a Partially Open Space 风对部分开放空间泄漏氢气扩散影响的分析研究
IF 1.2 4区 工程技术 Q2 NUCLEAR SCIENCE & TECHNOLOGY
Journal of Nuclear Science and Technology
Pub Date : 2024-01-04 DOI: 10.1080/00223131.2024.2302540
A. Terada, R. Nagaishi
{"title":"Analytical studies on effects of wind on dispersion of hydrogen leaked in a Partially Open Space","authors":"A. Terada, R. Nagaishi","doi":"10.1080/00223131.2024.2302540","DOIUrl":"https://doi.org/10.1080/00223131.2024.2302540","url":null,"abstract":"","PeriodicalId":16526,"journal":{"name":"Journal of Nuclear Science and Technology","volume":"42 7","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139384974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Calculations and analysis of n+ 52 Cr reactions below 20 MeV 20 MeV 以下 n+ 52 Cr 反应的计算和分析
IF 1.2 4区 工程技术 Q2 NUCLEAR SCIENCE & TECHNOLOGY
Journal of Nuclear Science and Technology
Pub Date : 2024-01-04 DOI: 10.1080/00223131.2023.2294191
Wenye Wang, Jimin Wang, Yinlu Han, Tao Xi, Yongli Jin, Ruirui Xu, Yue Zhang
{"title":"Calculations and analysis of n+\u0000 52\u0000 Cr reactions below 20 MeV","authors":"Wenye Wang, Jimin Wang, Yinlu Han, Tao Xi, Yongli Jin, Ruirui Xu, Yue Zhang","doi":"10.1080/00223131.2023.2294191","DOIUrl":"https://doi.org/10.1080/00223131.2023.2294191","url":null,"abstract":"","PeriodicalId":16526,"journal":{"name":"Journal of Nuclear Science and Technology","volume":"59 4","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139384607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relationship between human error and occupational stress of commissioning workers in nuclear power plants: the mediating effects of anxiety 核电站调试工人人为失误与职业压力之间的关系：焦虑的中介效应
IF 1.2 4区 工程技术 Q2 NUCLEAR SCIENCE & TECHNOLOGY
Journal of Nuclear Science and Technology
Pub Date : 2024-01-02 DOI: 10.1080/00223131.2023.2300313
Yuan Kuang, Shuicheng Tian, Guangli Li, Dejun Zhao, Tao Qing
The commissioning of a nuclear power plant (NPP) is a high-intensity job with severe consequences in the event of accidents. Commissioning workers are exposed to both mentally and physically demand...
核电站（NPP）的调试是一项高强度的工作，一旦发生事故，后果将十分严重。调试工人面临着精神和体力上的双重要求......
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引用次数: 0
Human reliability analysis of shared equipment in multi-unit site 多单元工地共享设备的人为可靠性分析
IF 1.2 4区 工程技术 Q2 NUCLEAR SCIENCE & TECHNOLOGY
Journal of Nuclear Science and Technology
Pub Date : 2024-01-02 DOI: 10.1080/00223131.2023.2300304
Wanxin Feng, Jinkai Wang, Zhixin Xu, Ming Wang, Li Wen, Yu Yu, Zecong Li
Currently, there is no mature method for calculating the probability of human failure that occurs in multi-unit. In this study, the single-unit HRA is expanded and improved, and we have compiled a ...
目前，还没有成熟的方法来计算多单元发生人为故障的概率。在本研究中，我们对单一单元的人为失误概率进行了扩展和改进，并编制了 ...
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引用次数: 0
Development of a radiation tolerant laser-induced breakdown spectroscopy system using a single crystal micro-chip laser for remote elemental analysis 利用单晶微芯片激光器开发用于远程元素分析的耐辐射激光诱导击穿光谱系统
IF 1.2 4区 工程技术 Q2 NUCLEAR SCIENCE & TECHNOLOGY
Journal of Nuclear Science and Technology
Pub Date : 2024-01-02 DOI: 10.1080/00223131.2023.2298485
Koji Tamura, Ryuzo Nakanishi, Hironori Ohba, Takahiro Karino, Takuya Shibata, Takunori Taira, Ikuo Wakaida
For the development of the remote elemental analysis method in a radiation environment based on the laser-induced breakdown spectroscopy (LIBS), the radiation effects on the laser oscillation prope...
为了开发基于激光诱导击穿光谱（LIBS）的辐射环境下的远程元素分析方法，必须考虑辐射对激光振荡过程的影响，以及辐射对元素分析的影响。
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引用次数: 0
TFR1-Mediated Iron Metabolism Orchestrates Tumor Ferroptosis and Immunity in Non-Small Cell Lung Cancer. TFR1介导的铁代谢可协调非小细胞肺癌中的肿瘤铁变态反应和免疫。
IF 2.4 4区 工程技术 Q2 NUCLEAR SCIENCE & TECHNOLOGY
Journal of Nuclear Science and Technology
Pub Date : 2024-01-01 DOI: 10.1615/JEnvironPatholToxicolOncol.2023049084
Zunqiao Wang, Xingkai Yao, Keping Wang, Bin Wang

This study aimed to investigate the underlying molecular mechanisms of transferrin receptor (TFR1) in non-small cell lung cancer (NSCLC). Histological analysis was performed using hematoxylin-eosin (HE) staining. The number of CD8+ T cell were determined by flow cytometry and immunofluorescence assays. mRNA levels were analyzed by qRT-PCR. Protein expression was detected by western blot. Ferroptosis was detected by using propidium iodide (PI) staining. Xenograft experiment was applied for determining tumor growth. The results showed that interferon (IFN)-γ plus iron dextran (FeDx) induced iron overload and the ferroptosis of NSCLC cells. Moreover, IFN-γ-mediated upregulation of TFR1 promoted ferritinophagy and tumor cell ferroptosis via blocking via blocking ferritin heavy chain 1 (FTH1)/ ferritin light chain (FTL) signaling. However, TFR1 knockout suppressed the ferroptosis of tumor cells. Furthermore, FeDx-mediated iron overload promoted the sensitivity of anti-programmed death ligand 1 (PD-L1) therapies. Clinically, TFR1 was downregulated in NSCLC patients. Low levels of TFR1 predicted decreased CD8+ T cells. Taken together, IFN-γ combined with iron metabolism therapies may provide a novel alternative for NSCLC.

本研究旨在探讨转铁蛋白受体（TFR1）在非小细胞肺癌（NSCLC）中的潜在分子机制。采用苏木精-伊红（HE）染色进行组织学分析。CD8+T细胞的数量通过流式细胞术和免疫荧光测定法确定。蛋白表达用 Western 印迹法检测。碘化丙啶（PI）染色检测铁变态反应。异种移植实验用于确定肿瘤的生长情况。结果表明，干扰素（IFN）-γ加右旋糖酐铁（FeDx）可诱导NSCLC细胞铁超载和铁突变。此外，IFN-γ介导的TFR1上调通过阻断铁蛋白重链1（FTH1）/铁蛋白轻链（FTL）信号传导，促进了铁蛋白吞噬和肿瘤细胞的铁嗜性。然而，TFR1基因敲除抑制了肿瘤细胞的铁突变。此外，FeDx介导的铁过载会提高抗程序性死亡配体1（PD-L1）疗法的敏感性。临床上，TFR1在NSCLC患者中被下调。低水平的TFR1预示着CD8+ T细胞的减少。综上所述，IFN-γ与铁代谢疗法相结合可能会为NSCLC提供一种新的替代疗法。
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引用次数: 0
A review on failure behavior and life prediction of circulation pumps in lead-bismuth eutectic cooled reactors 铅铋共晶冷却反应堆循环泵的失效行为和寿命预测综述
IF 1.2 4区 工程技术 Q2 NUCLEAR SCIENCE & TECHNOLOGY
Journal of Nuclear Science and Technology
Pub Date : 2023-12-28 DOI: 10.1080/00223131.2023.2295440
Fan Wang, Fei Xiao, Ma Wensheng, Tianzhou Wang, Tao Wang
In advanced nuclear power systems, structure materials have compatibility problems with lead-bismuth eutectic coolants such as liquid metal corrosion, and the corrosion failure behavior of the circ...
在先进的核电系统中，结构材料与铅铋共晶冷却剂存在相容性问题，例如液态金属腐蚀，以及循环系统的腐蚀失效行为。
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引用次数: 0
Double-differential cross sections for charged particle emissions from α particle impinging on Al at 230 MeV/u 230 MeV/u α粒子撞击铝时带电粒子发射的双差分截面
IF 1.2 4区 工程技术 Q2 NUCLEAR SCIENCE & TECHNOLOGY
Journal of Nuclear Science and Technology
Pub Date : 2023-12-27 DOI: 10.1080/00223131.2023.2294192
Toshimasa Furuta, Yusuke Uozumi, Yuji Yamaguchi, Yosuke Iwamoto, Yusuke Koba, Elena Velicheva, Vladimir Kalinnikov, Zviadi Tsamalaidze, Petr Evtoukhovitch
Charged particle production from α particle fragmentation reactions was investigated experimentally by measurement of 230-MeV/u α particles bombarding an aluminum target. Double differential cross ...
通过测量轰击铝靶的 230-MeV/u α 粒子，对 α 粒子碎裂反应产生的带电粒子进行了实验研究。双差分交叉...
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引用次数: 0
Measurement of the neutron capture cross section of 185Re in the keV energy region 测量 185Re 在 keV 能量区的中子俘获截面
IF 1.2 4区 工程技术 Q2 NUCLEAR SCIENCE & TECHNOLOGY
Journal of Nuclear Science and Technology
Pub Date : 2023-12-26 DOI: 10.1080/00223131.2023.2298749
T. Katabuchi, Yaoki Sato, Karin Takebe, Masayuki Igashira, Seigo Umezawa, Ryo Fujioka, Tatsuhiro Saito, Nobuyuki Iwamoto
Despite various applications of Rhenium in nuclear science and engineering, there have been limited measurements of the neutron capture cross section of 185Re in the keV energy region, with existin...
尽管铼在核科学和工程学中有多种应用，但对185Re在keV能量区的中子俘获截面的测量却很有限，现有的测量结果表明...
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引用次数: 0
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