首页 > 最新文献

2010 3rd International Symposium on Applied Sciences in Biomedical and Communication Technologies (ISABEL 2010)最新文献

英文 中文
Simulation of daily ECG monitoring strategies for atrial fibrillation patients 房颤患者日常心电监护策略的模拟
F. Censi, G. Calcagnini, E. Mattei, M. Triventi, P. Bartolini
Patients with arrhythmias would greatly benefit from daily ECG monitoring, both for diagnosis and therapy optimization. The aim of this study was to simulate several ECG monitoring strategies which could help in optimizing a home monitoring device. Simulations were performed using data from patients implanted with DDD-CLS pacemaker for Brady-Tachy Syndrome (Burden II Study). The data analysis was performed considering the mode switch list which includes date, time and duration of each mode switch episode. Starting from this database, daily monitoring strategies were simulated by varying the hour of beginning and the duration of each daily recording, and the number of monitoring consecutive days. The number of detected patients varies depending on the hour of the day when the monitoring starts, with peaks in the morning (9–10 A. M.). The lowest number of detected patients is obtained at late evening (10–11 P. M.). An optimized 2-hour monitoring for 60 consecutive days can detect almost 60% of patients experiencing AF episodes in the observational period compared with 10% and 35% of detected patients with AF episodes obtained using one-day and 7-days Holter monitoring, respectively.
对心律失常患者进行日常心电图监测,对诊断和优化治疗都大有裨益。本研究的目的是模拟几种心电图监测策略,以帮助优化家庭监测设备。模拟使用植入DDD-CLS起搏器治疗布兰迪-心动过速综合征患者的数据(Burden II研究)。考虑模式切换列表,包括每个模式切换集的日期、时间和持续时间,进行数据分析。从该数据库开始,通过改变每天记录的开始时间和持续时间以及连续监测天数来模拟日常监测策略。检测到的患者数量取决于监测开始的时间,高峰在上午(上午9-10点)。m)。在深夜(晚上10-11点)检测到的患者人数最少。优化的连续60天2小时监测可以在观察期内发现近60%的AF发作患者,而使用1天和7天动态心电图监测的AF发作患者分别为10%和35%。
{"title":"Simulation of daily ECG monitoring strategies for atrial fibrillation patients","authors":"F. Censi, G. Calcagnini, E. Mattei, M. Triventi, P. Bartolini","doi":"10.1109/ISABEL.2010.5702923","DOIUrl":"https://doi.org/10.1109/ISABEL.2010.5702923","url":null,"abstract":"Patients with arrhythmias would greatly benefit from daily ECG monitoring, both for diagnosis and therapy optimization. The aim of this study was to simulate several ECG monitoring strategies which could help in optimizing a home monitoring device. Simulations were performed using data from patients implanted with DDD-CLS pacemaker for Brady-Tachy Syndrome (Burden II Study). The data analysis was performed considering the mode switch list which includes date, time and duration of each mode switch episode. Starting from this database, daily monitoring strategies were simulated by varying the hour of beginning and the duration of each daily recording, and the number of monitoring consecutive days. The number of detected patients varies depending on the hour of the day when the monitoring starts, with peaks in the morning (9–10 A. M.). The lowest number of detected patients is obtained at late evening (10–11 P. M.). An optimized 2-hour monitoring for 60 consecutive days can detect almost 60% of patients experiencing AF episodes in the observational period compared with 10% and 35% of detected patients with AF episodes obtained using one-day and 7-days Holter monitoring, respectively.","PeriodicalId":165367,"journal":{"name":"2010 3rd International Symposium on Applied Sciences in Biomedical and Communication Technologies (ISABEL 2010)","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132330850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Efficient pilot carrier acquisition and tracking in detect and avoid signal processing 在检测和避免信号处理中,有效地获取和跟踪导频载波
S. Reisenfeld
For the detect and avoid operation in cognitive radio systems, there is often a requirement to rapidly acquire a pilot carrier in a large frequency uncertainty band. This paper presents a method for rapid pilot carrier acquisition with extremely low computational complexity. A low latency, iterative frequency estimation algorithm is introduced, which accurately determines the pilot carrier frequency and initializes a phase locked loop center frequency. The phase locked loop, with essentially no initial frequency error, is then able to rapidly acquire the pilot signal. Because a narrow band phase locked loop can be used, extremely good phase error tracking performance is achievable with small acquisition time.
在认知无线电系统的探测与躲避操作中,往往需要在较大的频率不确定范围内快速获取导频载波。本文提出了一种计算复杂度极低的快速导频载波获取方法。介绍了一种低延迟迭代频率估计算法,该算法能够准确地确定导频载波频率并初始化锁相环中心频率。锁相环基本上没有初始频率误差,因此能够快速获取导频信号。由于可以使用窄带锁相环,因此可以在较小的采集时间内实现极好的相位误差跟踪性能。
{"title":"Efficient pilot carrier acquisition and tracking in detect and avoid signal processing","authors":"S. Reisenfeld","doi":"10.1109/ISABEL.2010.5702798","DOIUrl":"https://doi.org/10.1109/ISABEL.2010.5702798","url":null,"abstract":"For the detect and avoid operation in cognitive radio systems, there is often a requirement to rapidly acquire a pilot carrier in a large frequency uncertainty band. This paper presents a method for rapid pilot carrier acquisition with extremely low computational complexity. A low latency, iterative frequency estimation algorithm is introduced, which accurately determines the pilot carrier frequency and initializes a phase locked loop center frequency. The phase locked loop, with essentially no initial frequency error, is then able to rapidly acquire the pilot signal. Because a narrow band phase locked loop can be used, extremely good phase error tracking performance is achievable with small acquisition time.","PeriodicalId":165367,"journal":{"name":"2010 3rd International Symposium on Applied Sciences in Biomedical and Communication Technologies (ISABEL 2010)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130793008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
On spectrum sensing duration in cognitive wireless sensor networks 认知无线传感器网络频谱感知持续时间研究
F. Penna, Hussein Khaleel, C. Pastrone, R. Tomasi, M. Spirito
Frequency agility is considered as an indispensable feature of next-generation wireless sensor networks (WSNs), which will have to cope with highly interfered environments due to the increasing diffusion of wireless devices operating in unlicensed bands. In this paper we investigate some design aspects related to spectrum sensing in “cognitive” WSNs, relating the duration of sensing time to the probability of error in channel selection and analyzing the tradeoff between sensing duration and average throughput. Results are based on a realistic model, consistent with previous experimental works and existing testbeds.
频率敏捷性被认为是下一代无线传感器网络(WSNs)不可或缺的特征,由于无线设备在未经许可的频段上工作的日益扩散,下一代无线传感器网络将不得不应对高度干扰的环境。在本文中,我们研究了“认知”无线传感器网络中与频谱感知相关的一些设计方面,将感知时间的持续时间与信道选择中的错误概率联系起来,并分析了感知时间与平均吞吐量之间的权衡。结果基于一个真实的模型,与先前的实验工作和现有的测试平台一致。
{"title":"On spectrum sensing duration in cognitive wireless sensor networks","authors":"F. Penna, Hussein Khaleel, C. Pastrone, R. Tomasi, M. Spirito","doi":"10.1109/ISABEL.2010.5702805","DOIUrl":"https://doi.org/10.1109/ISABEL.2010.5702805","url":null,"abstract":"Frequency agility is considered as an indispensable feature of next-generation wireless sensor networks (WSNs), which will have to cope with highly interfered environments due to the increasing diffusion of wireless devices operating in unlicensed bands. In this paper we investigate some design aspects related to spectrum sensing in “cognitive” WSNs, relating the duration of sensing time to the probability of error in channel selection and analyzing the tradeoff between sensing duration and average throughput. Results are based on a realistic model, consistent with previous experimental works and existing testbeds.","PeriodicalId":165367,"journal":{"name":"2010 3rd International Symposium on Applied Sciences in Biomedical and Communication Technologies (ISABEL 2010)","volume":"138 1-2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123696060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Wavelet analysis of human photoreceptoral response 人体光感受器反应的小波分析
R. Barraco, D. P. Adorno, M. Brai
Feature detection of biomedical signals is crucial for deepening our knowledge of the physiological phenomena giving rise to them. To achieve this aim, even if many analytic approaches have been suggested only few are able to deal with signals whose features are time dependent, and to provide useful clinical information. In this work we use the wavelet analysis to extract peculiarities of the early response of the photoreceptoral human system, known as a-wave ERG-component. The analysis of the a-wave features is important since this component reflects the functional integrity of the two populations of photoreceptors, rods and cones whose activation dynamics are not well known. Moreover, in incipient photoreceptoral pathologies the eventual anomalies in a-wave are not always detectable with a naked eye analysis of the traces. We here propose the possibility to discriminate the pathologic from the healthy traces throughout the differentiation of their time-frequency characteristics, revealed by the wavelet analysis. The investigated pathologies are the Achromatopsia, a cone disease and the Congenital Stationary Night Blindness, a rod trouble. The results show that the number of stable frequencies present and their times of occurrence are indicative of the status of the retinal photoreceptors. In particular, in the pathological cases, the frequency components shift toward lower values and change their times of occurrence, with respect to healthy traces.
生物医学信号的特征检测对于加深我们对产生这些信号的生理现象的认识至关重要。为了实现这一目标,即使已经提出了许多分析方法,但只有少数能够处理特征与时间相关的信号,并提供有用的临床信息。在这项工作中,我们使用小波分析来提取人体光感受器系统的早期反应特性,称为a波ergg成分。对a波特征的分析很重要,因为这一成分反映了两种光感受器的功能完整性,杆状体和锥状体,其激活动力学尚不清楚。此外,在早期的光感受器病理中,最终的a波异常并不总是用肉眼分析痕迹来检测到的。我们在这里提出了通过小波分析揭示的病理痕迹的时频特征的区分来区分病理痕迹和健康痕迹的可能性。所调查的病理是色盲,一种锥体疾病和先天性静止性夜盲症,一种杆状疾病。结果表明,存在稳定频率的数量及其出现的次数表明视网膜光感受器的状态。特别是,在病理情况下,频率分量向较低的值移动,并改变其出现的时间,相对于健康的痕迹。
{"title":"Wavelet analysis of human photoreceptoral response","authors":"R. Barraco, D. P. Adorno, M. Brai","doi":"10.1109/ISABEL.2010.5702846","DOIUrl":"https://doi.org/10.1109/ISABEL.2010.5702846","url":null,"abstract":"Feature detection of biomedical signals is crucial for deepening our knowledge of the physiological phenomena giving rise to them. To achieve this aim, even if many analytic approaches have been suggested only few are able to deal with signals whose features are time dependent, and to provide useful clinical information. In this work we use the wavelet analysis to extract peculiarities of the early response of the photoreceptoral human system, known as a-wave ERG-component. The analysis of the a-wave features is important since this component reflects the functional integrity of the two populations of photoreceptors, rods and cones whose activation dynamics are not well known. Moreover, in incipient photoreceptoral pathologies the eventual anomalies in a-wave are not always detectable with a naked eye analysis of the traces. We here propose the possibility to discriminate the pathologic from the healthy traces throughout the differentiation of their time-frequency characteristics, revealed by the wavelet analysis. The investigated pathologies are the Achromatopsia, a cone disease and the Congenital Stationary Night Blindness, a rod trouble. The results show that the number of stable frequencies present and their times of occurrence are indicative of the status of the retinal photoreceptors. In particular, in the pathological cases, the frequency components shift toward lower values and change their times of occurrence, with respect to healthy traces.","PeriodicalId":165367,"journal":{"name":"2010 3rd International Symposium on Applied Sciences in Biomedical and Communication Technologies (ISABEL 2010)","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124499740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Distributed spectrum sensing for cognitive radio networks with heterogeneous traffic 具有异构业务的认知无线电网络的分布式频谱感知
Sabita Maharjan, C. Yuen, Y. Chew, Yan Zhang, S. Gjessing
Cooperative spectrum sensing improves reliability and the detection performance of sensing. However, the fully cooperative scenario may not be realistic to assume in many cases. We consider a cognitive radio network with heavy traffic users and light traffic users and analyze their behavior towards sensing using the concept of mixed strategy Nash equilibrium. Further, we design a distributed game using evolutionary game theory such that as long as light traffic users are present, they share the sensing responsibility while heavy traffic users get a free ride. Finally, the evolution dynamics is shown to converge to the evolutionarily stable strategy for the case of multiple users.
协同频谱感知提高了感知的可靠性和检测性能。然而,在许多情况下,完全合作的情景可能是不现实的。我们考虑了一个具有大流量用户和轻流量用户的认知无线网络,并利用混合策略纳什均衡的概念分析了他们的感知行为。进一步,我们利用进化博弈理论设计了一种分布式博弈,只要交通量小的用户存在,他们就分担感知责任,而交通量大的用户则免费乘车。最后,在多用户情况下,进化动力学收敛于进化稳定策略。
{"title":"Distributed spectrum sensing for cognitive radio networks with heterogeneous traffic","authors":"Sabita Maharjan, C. Yuen, Y. Chew, Yan Zhang, S. Gjessing","doi":"10.1109/ISABEL.2010.5702849","DOIUrl":"https://doi.org/10.1109/ISABEL.2010.5702849","url":null,"abstract":"Cooperative spectrum sensing improves reliability and the detection performance of sensing. However, the fully cooperative scenario may not be realistic to assume in many cases. We consider a cognitive radio network with heavy traffic users and light traffic users and analyze their behavior towards sensing using the concept of mixed strategy Nash equilibrium. Further, we design a distributed game using evolutionary game theory such that as long as light traffic users are present, they share the sensing responsibility while heavy traffic users get a free ride. Finally, the evolution dynamics is shown to converge to the evolutionarily stable strategy for the case of multiple users.","PeriodicalId":165367,"journal":{"name":"2010 3rd International Symposium on Applied Sciences in Biomedical and Communication Technologies (ISABEL 2010)","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115645927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Introducing privacy-awareness in remote healthcare monitoring 在远程医疗监控中引入隐私意识
G. Lioudakis, Georgios Lamprinakos, E. Kosmatos, D. Kaklamani, I. Venieris
The creation of smart spaces for remote healthcare monitoring is a very prominent example of patients' life improvement by healthcare ICT, eliminating in certain cases the need for hospitalization of patients that require monitoring. On the other hand, services as such create concerns and are characterized by implications with respect to personal privacy. In order to limit the disclosure and misuse of patients' personal data, this paper discusses the access control solution considered by the inCasa project for the enforcement of fair information practices in the context of remote healthcare monitoring.
创建用于远程医疗保健监测的智能空间是通过医疗保健信息通信技术改善患者生活的一个非常突出的例子,在某些情况下消除了需要监测的患者住院的需要。另一方面,服务本身会引起关注,并以涉及个人隐私为特征。为了限制患者个人数据的披露和滥用,本文讨论了inCasa项目考虑的访问控制解决方案,用于在远程医疗监控环境中执行公平的信息实践。
{"title":"Introducing privacy-awareness in remote healthcare monitoring","authors":"G. Lioudakis, Georgios Lamprinakos, E. Kosmatos, D. Kaklamani, I. Venieris","doi":"10.1109/ISABEL.2010.5702886","DOIUrl":"https://doi.org/10.1109/ISABEL.2010.5702886","url":null,"abstract":"The creation of smart spaces for remote healthcare monitoring is a very prominent example of patients' life improvement by healthcare ICT, eliminating in certain cases the need for hospitalization of patients that require monitoring. On the other hand, services as such create concerns and are characterized by implications with respect to personal privacy. In order to limit the disclosure and misuse of patients' personal data, this paper discusses the access control solution considered by the inCasa project for the enforcement of fair information practices in the context of remote healthcare monitoring.","PeriodicalId":165367,"journal":{"name":"2010 3rd International Symposium on Applied Sciences in Biomedical and Communication Technologies (ISABEL 2010)","volume":"124 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114329817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Classification of biophysical changes during food allergy challenges 食物过敏时生物物理变化的分类
N. Twomey, S. Faul, D. Daly, J. Hourihane, W. Marnane
This paper details the process of oral food challenges (‘allergy tests’) and steps followed to investigate whether automatic classification of the tests is possible. It has been observed by trained staff that the mood and physiological signals of a subject being tested for allergies can change during the test if they are sensitive to the allergen they are being tested against. Data from thirteen subjects was recorded, and thirteen features were extracted from each of these datasets. The changes in the features were then analysed over the course of each test. It was noted that when a subject failed the challenge, some of the features extracted from the ECG trace changed suddenly near the time that the test was stopped. Threshold classification was employed, and ROC curves were generated. Some features gave rise to ROC areas of over 0.97 on certain subjects. An average ROC area of 0.57 was computed over all subjects and all features due to wide inter subject variability.
本文详细介绍了口腔食物挑战(“过敏测试”)的过程,以及调查测试自动分类是否可能的步骤。经过训练的工作人员观察到,如果被测试者对过敏原敏感,他们的情绪和生理信号在测试过程中会发生变化。记录13名受试者的数据,并从每个数据集中提取13个特征。然后在每次测试过程中分析特征的变化。值得注意的是,当受试者未通过挑战时,从ECG追踪中提取的一些特征在测试停止时突然发生变化。采用阈值分类,生成ROC曲线。某些特征导致某些受试者的ROC面积超过0.97。由于广泛的受试者间变异性,所有受试者和所有特征的平均ROC面积为0.57。
{"title":"Classification of biophysical changes during food allergy challenges","authors":"N. Twomey, S. Faul, D. Daly, J. Hourihane, W. Marnane","doi":"10.1109/ISABEL.2010.5702922","DOIUrl":"https://doi.org/10.1109/ISABEL.2010.5702922","url":null,"abstract":"This paper details the process of oral food challenges (‘allergy tests’) and steps followed to investigate whether automatic classification of the tests is possible. It has been observed by trained staff that the mood and physiological signals of a subject being tested for allergies can change during the test if they are sensitive to the allergen they are being tested against. Data from thirteen subjects was recorded, and thirteen features were extracted from each of these datasets. The changes in the features were then analysed over the course of each test. It was noted that when a subject failed the challenge, some of the features extracted from the ECG trace changed suddenly near the time that the test was stopped. Threshold classification was employed, and ROC curves were generated. Some features gave rise to ROC areas of over 0.97 on certain subjects. An average ROC area of 0.57 was computed over all subjects and all features due to wide inter subject variability.","PeriodicalId":165367,"journal":{"name":"2010 3rd International Symposium on Applied Sciences in Biomedical and Communication Technologies (ISABEL 2010)","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117015675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Principal component analysis of gene expression data: The case of atrial fibrillation 基因表达数据的主成分分析:心房颤动病例
F. Censi, G. Calcagnini, P. Bartolini, A. Giuliani
Atrial fibrillation (AF) is the most common persistent cardiac arrhythmia. AF is also associated with extensive structural, contractile, and electrophysiological remodeling, which can sustain AF itself. The understanding of the molecular events of these remodeling processes is essential for the development of new targeted therapeutic interventions. In this paper microarray data related to permanent AF patients and controls were analyzed using the principal components extracted from a matrix having gene expression values as statistical units and patients as variables. The data were obtained from the public functional genomics data repository of the National Institute of Health (called Gene Expression Omnibus, GEO). Data from record #GSE2240 have been analyzed, consisting of samples of right atrial myocardium (appendage). Data were related to two Affymetrix platforms U133A and U133B. Right atrial appendages were obtained from 30 patients undergoing open heart surgery for valve repair or coronary artery bypass grafting. Of these, 10 patients had permanent AF and 20 patients had no history of AF. The differences in gene expression profiles between permanent AF patients and controls are related to a very small part of the data variability. However, the analysis of such a small difference in terms of factor loadings and scores, succeed in discriminating patients from controls and in offering a mechanistic view relating AF condition to both cardiac muscle organization and inflammatory processes.
心房颤动(AF)是最常见的持续性心律失常。房颤还与广泛的结构、收缩和电生理重构有关,这些重构可以维持房颤本身。了解这些重塑过程的分子事件对于开发新的靶向治疗干预措施至关重要。本文采用以基因表达值为统计单位,以患者为变量的矩阵提取主成分,对永久性房颤患者和对照组的微阵列数据进行分析。这些数据来自美国国立卫生研究院(National Institute of Health)的公共功能基因组数据库(称为Gene Expression Omnibus, GEO)。对记录#GSE2240的数据进行分析,包括右心房心肌(附件)样本。数据涉及两个Affymetrix平台U133A和U133B。从30例接受心脏直视手术或冠状动脉旁路移植术的患者中获得右心房附件。其中,10名患者患有永久性房颤,20名患者没有房颤病史。永久性房颤患者和对照组之间基因表达谱的差异与数据变异性的很小一部分有关。然而,就因子负荷和评分而言,分析如此微小的差异,成功地将患者与对照组区分开来,并提供了与心肌组织和炎症过程相关的AF状况的机制观点。
{"title":"Principal component analysis of gene expression data: The case of atrial fibrillation","authors":"F. Censi, G. Calcagnini, P. Bartolini, A. Giuliani","doi":"10.1109/ISABEL.2010.5702916","DOIUrl":"https://doi.org/10.1109/ISABEL.2010.5702916","url":null,"abstract":"Atrial fibrillation (AF) is the most common persistent cardiac arrhythmia. AF is also associated with extensive structural, contractile, and electrophysiological remodeling, which can sustain AF itself. The understanding of the molecular events of these remodeling processes is essential for the development of new targeted therapeutic interventions. In this paper microarray data related to permanent AF patients and controls were analyzed using the principal components extracted from a matrix having gene expression values as statistical units and patients as variables. The data were obtained from the public functional genomics data repository of the National Institute of Health (called Gene Expression Omnibus, GEO). Data from record #GSE2240 have been analyzed, consisting of samples of right atrial myocardium (appendage). Data were related to two Affymetrix platforms U133A and U133B. Right atrial appendages were obtained from 30 patients undergoing open heart surgery for valve repair or coronary artery bypass grafting. Of these, 10 patients had permanent AF and 20 patients had no history of AF. The differences in gene expression profiles between permanent AF patients and controls are related to a very small part of the data variability. However, the analysis of such a small difference in terms of factor loadings and scores, succeed in discriminating patients from controls and in offering a mechanistic view relating AF condition to both cardiac muscle organization and inflammatory processes.","PeriodicalId":165367,"journal":{"name":"2010 3rd International Symposium on Applied Sciences in Biomedical and Communication Technologies (ISABEL 2010)","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124780205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Ultra Wide Band real-time location system for cinematic survey in sports 用于体育电影调查的超宽带实时定位系统
L. Mucchi, F. Trippi, A. Carpini
Our experimental campaign shows how a real-time location system based on Ultra Wide Band (UWB) impulses can be fruitfully used to collect cinematic parameters in order to define the health status of an athlete objectively. The Ubisense UWB system has been used to monitor the performance of a professional athlete during the recovering time after a surgery. The cinematic data has been processed in order to have all the performance comparable. This work demonstrates that the UWB localization can be efficiently used in order to show the increase in the muscular capacity and to measure it.
我们的实验活动展示了基于超宽带(UWB)脉冲的实时定位系统如何有效地用于收集电影参数,以便客观地定义运动员的健康状态。Ubisense超宽带系统已被用于监测一名职业运动员手术后恢复期的表现。为了使所有的性能具有可比性,对电影数据进行了处理。这项工作表明,超宽带定位可以有效地用于显示和测量肌肉容量的增加。
{"title":"Ultra Wide Band real-time location system for cinematic survey in sports","authors":"L. Mucchi, F. Trippi, A. Carpini","doi":"10.1109/ISABEL.2010.5702934","DOIUrl":"https://doi.org/10.1109/ISABEL.2010.5702934","url":null,"abstract":"Our experimental campaign shows how a real-time location system based on Ultra Wide Band (UWB) impulses can be fruitfully used to collect cinematic parameters in order to define the health status of an athlete objectively. The Ubisense UWB system has been used to monitor the performance of a professional athlete during the recovering time after a surgery. The cinematic data has been processed in order to have all the performance comparable. This work demonstrates that the UWB localization can be efficiently used in order to show the increase in the muscular capacity and to measure it.","PeriodicalId":165367,"journal":{"name":"2010 3rd International Symposium on Applied Sciences in Biomedical and Communication Technologies (ISABEL 2010)","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125327897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Hybrid Honey Bees Mating Optimisation algorithm to assign terminals to concentrators 混合蜜蜂交配优化算法分配终端到集中器
E. Bernardino, A. Bernardino, J. M. Sánchez-Pérez, J. Gómez-Pulido, M. A. Vega-Rodríguez
In this paper we propose a new approach to assign terminals to concentrators using a Hybrid Honey Bees Mating Optimisation algorithm. Honey Bees Mating Optimisation (HBMO) algorithm is a swarm-based optimisation algorithm, which simulates the mating process of real honey bees. We apply a hybridisation of HBMO to solve a combinatorial optimisation problem known as Terminal Assignment Problem (TAP). The purpose is to connect a given set of terminals to a given set of concentrators and minimise the link cost to form a communication network. The feasibility of Hybrid HBMO is demonstrated and compared with the solutions obtained by other algorithms from literature over different TAP instances.
在本文中,我们提出了一种新的方法来分配终端集中使用混合蜜蜂交配优化算法。蜜蜂交配优化算法(HBMO)是一种基于群体的优化算法,它模拟了真实蜜蜂的交配过程。我们应用HBMO的杂交来解决被称为终端分配问题(TAP)的组合优化问题。其目的是将一组给定的终端连接到一组给定的集中器,并使链路成本最小化,从而形成一个通信网络。在不同的TAP实例上,证明了混合HBMO的可行性,并与文献中其他算法的解进行了比较。
{"title":"Hybrid Honey Bees Mating Optimisation algorithm to assign terminals to concentrators","authors":"E. Bernardino, A. Bernardino, J. M. Sánchez-Pérez, J. Gómez-Pulido, M. A. Vega-Rodríguez","doi":"10.1109/ISABEL.2010.5702845","DOIUrl":"https://doi.org/10.1109/ISABEL.2010.5702845","url":null,"abstract":"In this paper we propose a new approach to assign terminals to concentrators using a Hybrid Honey Bees Mating Optimisation algorithm. Honey Bees Mating Optimisation (HBMO) algorithm is a swarm-based optimisation algorithm, which simulates the mating process of real honey bees. We apply a hybridisation of HBMO to solve a combinatorial optimisation problem known as Terminal Assignment Problem (TAP). The purpose is to connect a given set of terminals to a given set of concentrators and minimise the link cost to form a communication network. The feasibility of Hybrid HBMO is demonstrated and compared with the solutions obtained by other algorithms from literature over different TAP instances.","PeriodicalId":165367,"journal":{"name":"2010 3rd International Symposium on Applied Sciences in Biomedical and Communication Technologies (ISABEL 2010)","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128321283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
期刊
2010 3rd International Symposium on Applied Sciences in Biomedical and Communication Technologies (ISABEL 2010)
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1