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Safely Easing Pain in Home Hospice Patients With Opioid Infusions: A Quality Improvement Project 安全缓解家庭安宁疗护病人输注阿片类药物的疼痛:一项品质改善计画。
IF 3.5 2区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-11-11 DOI: 10.1016/j.jpainsymman.2025.11.002
Linda Mae Abbott DNP, RN, Seungman Kim PhD, Alyce Ashcraft PhD, RN

Background

Opioid infusions are critical for managing pain in home hospice care but carry a high risk of medication errors. This quality improvement (QI) project evaluated adherence to a standardized PCA opioid infusion procedure and examined whether a nurse education intervention improved compliance.

Measures

Compliance was assessed using a ten-item checklist that captured key safety and documentation behaviors, including double-check verification, verification of nurse documentation and identification, expiration-date documentation, photo verification, documentation of pump lock and unlock, near-miss event reporting, compliance with the protocol, and identification of adverse events. Weekly average compliance scores were calculated for 47 weeks (29 pre-intervention and 18 post-intervention).

Intervention

The intervention consisted of a nurse education program focused on the standardized PCA opioid infusion procedure. Education covered double-check processes, standardized documentation using smart phrases, photo verification, and adherence to required safety steps. No patient-identifying information was collected.

Outcomes

Weekly average compliance scores significantly improved after the intervention (Mann–Whitney U test). Chi-square tests showed that several checklist items were significantly associated with the intervention period. Linear regression demonstrated that the intervention remained a significant predictor of higher compliance after controlling for nurse role and travel distance. No adverse events occurred during the study period.

Conclusions/Lessons Learned

Standardizing PCA opioid infusion procedures through focused nurse education, supported by digital documentation tools, improved compliance and strengthened patient safety in home hospice care. QI teams should consider combining education with standardized workflows and mobile documentation supports to reduce variability and enhance adherence.
背景:阿片类药物输注对于家庭安宁疗护中的疼痛管理至关重要,但存在较高的用药错误风险。这个质量改进(QI)项目评估了对标准化PCA阿片类药物输注程序的依从性,并检查了护士教育干预是否提高了依从性。措施:使用一份包含十项内容的检查表来评估依从性,该检查表记录了关键的安全和文件行为,包括复核验证、护士文件和身份验证、有效期文件、照片验证、泵锁定和解锁文件、未遂事件报告、协议遵守情况以及不良事件识别。每周平均依从性评分为47周(干预前29周,干预后18周)。干预:干预包括一个护士教育计划,重点是标准化的PCA阿片类药物输注程序。教育内容包括双重检查流程、使用智能短语的标准化文档、照片验证以及遵守所需的安全步骤。没有收集患者身份信息。结果:干预后每周平均依从性得分显著提高(Mann-Whitney U检验)。卡方检验显示,几个检查表项目与干预期显著相关。线性回归表明,在控制护士角色和出行距离后,干预仍然是较高依从性的显著预测因子。研究期间未发生不良事件。结论/经验教训:通过重点护士教育,在数字文件工具的支持下,标准化PCA阿片类药物输注程序,提高了家庭临终关怀的依从性并加强了患者安全。QI团队应该考虑将教育与标准化工作流和移动文档支持结合起来,以减少可变性并增强依从性。
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引用次数: 0
Implementing Pediatric Palliative Care in Vietnam: Initial Experiences and Lessons 在越南实施儿科姑息治疗:初步经验和教训。
IF 3.5 2区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-11-11 DOI: 10.1016/j.jpainsymman.2025.10.023
Miranda R. Adelmann MD , Huyen Thi Thanh Bui MD , Mevhibe Hocaoglu PhD , Quang Duy Huynh MD , Quynh Thi Hoang Nguyen MD , Mai Thi Tuyet Tran , Tung Son Nguyen , Y Quoc Y Nguyen , Thuan Hoa Vuong , Thơ Nguyen Minh Phan , Anh Hoang Mai Nguyen MD , Binh Tan Thanh Ho MD, PhD , Nam Tran Nguyen MD, MSC, CKII , Dinh Quang Truong MD, PhD , Eric L. Krakauer MD, PhD

Context

There remains an enormous unmet need for pediatric palliative care (PPC), especially in low- and middle-income countries (LMICs). Evaluation of existing PPC programs can inform development of emerging programs. In 2017, a PPC program was established at a major children’s hospital in Vietnam, a lower-middle-income country where palliative care development is at an early stage.

Objectives

We describe the development and operations of the first PPC program in Vietnam, and evaluate the program’s scope and early outcomes.

Methods

We conducted a retrospective cross-sectional study of all patients seen by the PPC inpatient consult service within an 18-month period. Descriptive statistics were used to identify trends in demographics, clinical characteristics, and end-of-life outcomes.

Results

Among 169 children (aged 0–15.6 years) who received PPC consultation, the most common diagnoses were cancer, traumatic injury, and congenital syndromes. Patients were referred by 14 different hospital departments. Psychosocial support was the most common PPC intervention (70%), while pain management was provided for 28% of patients. None of the patients with cancer died in the hospital.

Conclusion

By partnering with hospital leadership, creating opportunities for staff education, and adapting to the cultural and geographic setting, the PPC team overcame initial challenges to become a widely utilized, high-volume consult service. The PPC program may have reduced use of chemotherapy and cardiopulmonary resuscitation at end of life. The program’s strengths, challenges, and experiences may inform the development of emerging PPC programs in other LMICs.
背景:儿童姑息治疗(PPC)的巨大需求仍未得到满足,特别是在低收入和中等收入国家(LMICs)。对现有PPC项目的评估可以为新项目的开发提供信息。2017年,在姑息治疗发展处于早期阶段的中低收入国家越南,一家大型儿童医院建立了PPC项目。目的:我们描述了越南第一个PPC项目的发展和运作,并评估了该项目的范围和早期成果。方法:我们对18个月内PPC住院咨询服务的所有患者进行了回顾性横断面研究。描述性统计用于确定人口统计学、临床特征和临终预后的趋势。结果:169名接受PPC咨询的儿童(0 ~ 15.6岁)中,最常见的诊断为癌症、创伤性损伤和先天性综合征。患者由14个不同的医院部门转诊。心理社会支持是最常见的PPC干预(70%),而28%的患者提供疼痛管理。没有一个癌症病人死在医院里。结论:通过与医院领导合作,为员工教育创造机会,并适应文化和地理环境,PPC团队克服了最初的挑战,成为广泛使用的高容量咨询服务。PPC项目可能减少了生命末期化疗和心肺复苏的使用。该项目的优势、挑战和经验可以为其他中低收入国家新兴PPC项目的发展提供参考。
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引用次数: 0
Physicians' Perspectives and Attitudes Toward Palliative Care for Cancer Children in Mainland China 中国大陆医师对癌症儿童姑息治疗的看法与态度。
IF 3.5 2区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-11-11 DOI: 10.1016/j.jpainsymman.2025.11.003
Anan Zhang MD , Xuan Zhou MD , Jianmin Wang MD , Chenchen Sun MPH, MBA , Ximena Garcia-Quintero MD, MSc , Xinye Li MD , Dan Mu MD , Li Ma MD , Yan Han MD , Fang Zhang MD , Henglu Zhang MD , Xiuli Zhu MD , Godwin Job MS , Meenakshi Devidas MBA, PhD , Limei Mo MD , Yuanyuan Sun PhD , Runan Wang PhD , Yuanyuan Tuo MD , Yuqian Yao MD , Chao Shen MD , Michael J. McNeil MD, MPH

Context

Integrating pediatric palliative care (PPC) into the routine care of children with cancer improves outcomes for children and their families.

Objectives

Understanding physician perceptions of PPC in mainland China is crucial for enhancing PPC services.

Methods

This study adapted and translated the Assessing Doctors’ Attitudes on Palliative Treatment survey for use in mainland China. Univariate and multivariable linear regression analyses were used. Open-ended questions were analyzed qualitatively to supplement the quantitative data.

Results

A total of 368 physicians treating children with cancer from 25 provinces in China participated (98.4% response rate). Most were older than 35 years old and female. Only 108 (29.4%) participants had received palliative training, with 232 (63.0%) having access to palliative consultation. The most common misperceptions included the belief that early palliative care consultation increases parental burden and anxiety (51.3%) and that palliative care is synonymous with end-of-life care (55.7%). Previous access to palliative care education and consultation were two independent factors influencing physician alignment to the WHO guidance. Physician comfort in addressing the patient’s palliative care needs was low, and many (157, 42.7%) felt burdened by their inability to control children’s suffering at the end of life.

Conclusion

Although most institutions have joined the China PPC subgroup, gaps in knowledge, misconceptions, lack of access to PPC professionals, and physician’s discomfort remain significant challenges across mainland China. Addressing these issues through targeted education, capacity building and support systems are essential for improving care for children with cancer.
背景:。将儿科姑息治疗(PPC)纳入癌症儿童的常规护理可改善儿童及其家庭的预后。目的:。了解中国大陆医生对PPC的看法对于加强PPC服务至关重要。方法:。本研究改编并翻译了《评估医生对姑息治疗的态度调查》,以供中国大陆使用。采用单变量和多变量线性回归分析。对开放式问题进行定性分析,以补充定量数据。结果:。来自中国25个省份的368名治疗癌症儿童的医生参与了调查,有效率为98.4%。大多数患者年龄在35岁以上,为女性。只有108人(29.4%)接受过姑息治疗培训,232人(63.0%)接受过姑息治疗咨询。最常见的误解包括认为早期姑息治疗咨询增加了父母的负担和焦虑(51.3%),以及姑息治疗等同于临终关怀(55.7%)。以前接受姑息治疗教育和咨询是影响医生遵守世卫组织指南的两个独立因素。医生在解决患者姑息治疗需求方面的舒适度很低,许多(157,42.7%)感到负担沉重,因为他们无法控制孩子在生命结束时的痛苦。结论:。尽管大多数机构已经加入了中国PPC亚组,但知识差距、误解、缺乏获得PPC专业人员的机会以及医生的不适仍然是中国大陆面临的重大挑战。通过有针对性的教育、能力建设和支持系统来解决这些问题,对于改善对癌症儿童的护理至关重要。
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引用次数: 0
Staying Connected: A Longitudinal, Multisite, Interprofessional Rural Fellowship Collaboration 保持联系:纵向、多地点、跨专业的农村奖学金合作。
IF 3.5 2区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-11-11 DOI: 10.1016/j.jpainsymman.2025.11.001
Rhianon R. Liu MD , Rebecca N. Hutchinson MD, MPH , Stephen H. Berns MD , Nastasha Stitham NP, ACHPN , Jackie Fournier NP , John W. Wax MD , Lisa A. Stephens APRN, ACHPN, FPCN , Jonathan S. Jolin MD , Maxwell T. Vergo MD

Context

Four interprofessional hospice and palliative medicine (HPM) fellowship programs in rural northern New England states created an in-person educational retreat series.

Objectives

The goal of the series was to maximize shared educational resources and foster community amongst faculty and fellows, in an upstream attempt to improve recruitment/retention of clinicians in three rural states with inadequate access to specialty palliative care.

Methods

We organized three retreats per year starting in 2022. Each rural state hosted one retreat focused on a theme: 1) fundamental skills for HPM fellows, 2) advanced serious illness communication skills, and 3) leadership skills. Interprofessional faculty across the four programs co-taught sessions. Participating fellows and faculty were surveyed after the first two years to assess whether retreats met objectives.

Results

39 fellows and faculty completed the survey (17/22 fellows and 22/41 faculty; response rate 62%). At least 88% of fellows rated the retreats effective in strengthening their clinical, communication, teamwork, and leadership skills. The majority of faculty (72%) felt the retreats had a positive impact on their teaching. Over four-fifths of faculty and fellows felt the retreats increased their sense of belonging and decreased professional isolation. The retreats were a top factor influencing fellowship choice for 29% of fellows, as well as a major incentive to remain practicing in the region for 32% of faculty.

Conclusions

A series of in-person interprofessional educational retreats developed by four rural HPM fellowships strengthened fellow education, created connections among regional faculty and fellows, and were positively associated with fellow and faculty recruitment and retention
背景:四个跨专业的临终关怀和缓和医学(HPM)奖学金项目在新英格兰北部的农村地区创建了一个面对面的教育静修系列。目的:该系列的目标是最大限度地共享教育资源,促进教师和研究员之间的社区,在上游尝试改善三个农村州的临床医生的招聘/保留,这些州缺乏专业姑息治疗。方法:从2022年开始,我们每年组织三次闭关。每个乡村州都举办了一次静修活动,主题如下:1)HPM研究员的基本技能,2)高级重病沟通技巧,以及3)领导技能。四个项目的跨专业教师共同授课。参与的研究员和教师在头两年之后接受了调查,以评估务虚会是否达到了目标。结果:39名研究员和教师完成了调查(17/22名研究员和22/41名教师,回复率62%)。至少88%的学员认为静修在加强临床、沟通、团队合作和领导技能方面是有效的。大多数教师(72%)认为务虚会对他们的教学产生了积极影响。超过五分之四的教师和研究员认为,静修增加了他们的归属感,减少了职业孤立感。对29%的研究员来说,务虚会是影响他们选择奖学金的首要因素,对32%的教师来说,这也是他们留在该地区实习的主要动机。结论:由四个农村HPM研究员开发的一系列面对面的跨专业教育务静会加强了研究员教育,在地区教师和研究员之间建立了联系,并与研究员和教师的招聘和保留呈正相关。
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引用次数: 0
The Pediatric Cancer Care Experience (PACE) Questionnaire: Development and Validation of a Novel Instrument 儿童癌症护理经验(PACE)问卷:一种新型工具的开发和验证。
IF 3.5 2区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-11-11 DOI: 10.1016/j.jpainsymman.2025.10.034
Sona N. Kocinsky BS , Meghan E. Lindsay MPH , Sophia De Oliveira BA , Prasanna Ananth MD, MPH

Context

Patient-reported experience and outcome measures are crucial tools for assessing care quality. However, a critical gap exists in validated family-reported tools for the pediatric advanced cancer context.

Objectives

We aimed to develop, refine, and validate a novel parent-reported instrument to evaluate quality of care in children with advanced cancer.

Methods

We designed the “Pediatric Cancer Care Experience” (PACE) questionnaire as a parent-reported instrument to characterize cancer care quality, service delivery, and experience. The first draft of the questionnaire was revised based on face and content validity testing by healthcare professionals and cognitive interviews with parents of children with cancer. We then piloted the questionnaire in a multicenter, cross-sectional study of parents/guardians of children with advanced cancer. Using the responses from this cohort, we tested psychometric properties of the questionnaire, including exploratory factor analysis (EFA), internal consistency, and construct validity.

Results

PACE demonstrated robust face and content validity. The pilot cohort consisted of 158 parents/guardians of children with advanced cancer who predominantly self-identified as female (70%) and non-Hispanic White (58%). exploratory factor analysis (EFA) identified a three-factor model, including (1) therapeutic alliance, (2) collaborative care, and (3) prognostic communication and shared decision-making. We achieved sufficient internal consistency for all factors (Cronbach’s α range: 0.8–0.9). Construct validity testing suggested accurate measurement of the intended theoretical concepts.

Conclusion

PACE is a rigorously developed parent-reported instrument to assess care quality and experience in children with advanced cancer. Systematic deployment of PACE will enable future care delivery research and quality improvement.
背景:患者报告的经验和结果测量是评估护理质量的关键工具。然而,在儿科晚期癌症背景下,有效的家庭报告工具存在一个关键的差距。目的:我们旨在开发、完善和验证一种新的家长报告的工具来评估晚期癌症儿童的护理质量。方法:我们设计了“儿童癌症护理体验”(PACE)问卷,作为家长报告的工具来表征癌症护理质量、服务提供和体验。问卷初稿根据医疗保健专业人员的面孔效度和内容效度测试以及对癌症患儿家长的认知访谈进行了修订。然后,我们在一项针对晚期癌症儿童的父母/监护人的多中心横断面研究中试用了问卷。利用该队列的回答,我们测试了问卷的心理测量特性,包括探索性因素分析(EFA)、内部一致性和结构效度。结果:PACE具有显著的面孔效度和内容效度。试点队列包括158名晚期癌症儿童的父母/监护人,他们主要是女性(70%)和非西班牙裔白人(58%)。EFA确定了一个三因素模型,包括1治疗联盟,2协作护理,3预后沟通和共同决策。我们对所有因素都达到了足够的内部一致性(Cronbach's α范围:0.8-0.9)。建构效度检验建议对预期的理论概念进行准确的测量。结论:PACE是一种严格开发的家长报告的工具,用于评估晚期癌症儿童的护理质量和经验。PACE的系统部署将使未来的护理提供研究和质量改进成为可能。
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引用次数: 0
Beyond the Brushstrokes: Reassessing the Scope and Sustainability of Arts in Medicine Interventions for Cancer Care 超越笔触:重新评估癌症医疗干预艺术的范围和可持续性
IF 3.5 2区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-11-10 DOI: 10.1016/j.jpainsymman.2025.06.014
Ke Meng
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引用次数: 0
PC-FACS September 5, 2025 PC-FACS 2025年9月5日
IF 3.5 2区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-11-10 DOI: 10.1016/j.jpainsymman.2025.10.021
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引用次数: 0
PC-FACS October 3, 2025 PC-FACS 2025年10月3日。
IF 3.5 2区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-11-07 DOI: 10.1016/j.jpainsymman.2025.11.008
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引用次数: 0
Use of Nebulized Tranexamic Acid (TA) in Combination With Nebulized Recombinant Coagulation Factor VIIa to Treat Hemoptysis in Pediatric Patients With Cancer At End-Of-Life (EOL) 雾化氨甲环酸(TA)联合雾化重组凝血因子VIIa治疗小儿晚期癌症患者的咯血。
IF 3.5 2区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-11-07 DOI: 10.1016/j.jpainsymman.2025.11.005
Santosh Yatam Ganesh MD, MPH , Nelda Itzep MD , Eduardo Bruera MD
Hemoptysis is a distressing symptom for both patients and families at end of life (EOL). In the acute care setting, this can be managed surgically or medically. However, research regarding interventions, such as nebulized tranexamic acid (TA) and nebulized factor VIIa, for palliative management of hemoptysis at EOL is limited. In our case series, we found that combination of nebulized recombinant factor VIIa and nebulized TA relieved hemoptysis in both pediatric cancer patients at the end of life. This case series highlights the potential use of this combination to reduce suffering and distress secondary to hemoptysis in the palliative setting.
咯血是患者和家属在生命末期(EOL)的痛苦症状。在急性护理环境中,这可以通过手术或药物治疗来解决。然而,关于干预措施的研究,如雾化氨甲环酸(TA)和雾化VIIa因子,对于EOL咯血的姑息性管理是有限的。在我们的病例系列中,我们发现雾化重组VIIa因子和雾化TA联合使用可以缓解两名儿童癌症患者生命末期的咯血症状。本病例系列强调了这种组合的潜在用途,以减少在姑息环境中继发咯血的痛苦和痛苦。
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引用次数: 0
PC-FACS November 3, 2025 PC-FACS 2025年11月3日。
IF 3.5 2区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-11-07 DOI: 10.1016/j.jpainsymman.2025.11.007
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引用次数: 0
期刊
Journal of pain and symptom management
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