Pub Date : 2016-06-03DOI: 10.4172/2167-0846.1000249
A. Al-Khotani, N. Christidis
Childhood is the most crucial period in human life. From childhood on, children grow with their dreams and wishes and struggle their entire lives to reach their goals. However, an overabundance of fears and threats may negatively influence a child’s well-being. One such threat is a pain, which is a common experience in childhood that can be caused by trauma, serious accidents, psychological distress, diseases, or medical/dental treatments. Unfortunately, it is a common health problem that affects many aspects of function for millions of people around the world. Adolescence, on the other hand, is a transitional stage between childhood and adulthood that corresponds not only with the growth and development of the craniofacial region and other parts of the body but also of psychological and social perspectives. Studies report that pain in temporomandibular joint (TMJ) and associated orofacial structures are responsible for more than threequarter of dental appointments among adolescents. Further, besides the consequences of physical stress, impaired learning ability, psychological suffering, broken social relationships, and absence from school arising from acute untreated cases that have unfortunately become chronic, society bears an economic burden that is vital to consider. This short communication is intended for medical and dental caregivers to increase awareness of managing orofacial pain and temporomandibular disorders (OFP/TMD) in children and adolescents. This issue should be taken into consideration in order not only to minimize the suffering of pain, but also to avoid the associated psychosocial consequences. Furthermore, it clarifies why dentists (pediatric dentists in specific) should cooperate with other specialties to reduce expected consequences from continuing to adulthood.
{"title":"The Need for Multidisciplinary Handling of Orofacial Pain and Temporomandibular Disorders in Children and Adolescents","authors":"A. Al-Khotani, N. Christidis","doi":"10.4172/2167-0846.1000249","DOIUrl":"https://doi.org/10.4172/2167-0846.1000249","url":null,"abstract":"Childhood is the most crucial period in human life. From childhood on, children grow with their dreams and wishes and struggle their entire lives to reach their goals. However, an overabundance of fears and threats may negatively influence a child’s well-being. One such threat is a pain, which is a common experience in childhood that can be caused by trauma, serious accidents, psychological distress, diseases, or medical/dental treatments. Unfortunately, it is a common health problem that affects many aspects of function for millions of people around the world. Adolescence, on the other hand, is a transitional stage between childhood and adulthood that corresponds not only with the growth and development of the craniofacial region and other parts of the body but also of psychological and social perspectives. Studies report that pain in temporomandibular joint (TMJ) and associated orofacial structures are responsible for more than threequarter of dental appointments among adolescents. Further, besides the consequences of physical stress, impaired learning ability, psychological suffering, broken social relationships, and absence from school arising from acute untreated cases that have unfortunately become chronic, society bears an economic burden that is vital to consider. This short communication is intended for medical and dental caregivers to increase awareness of managing orofacial pain and temporomandibular disorders (OFP/TMD) in children and adolescents. This issue should be taken into consideration in order not only to minimize the suffering of pain, but also to avoid the associated psychosocial consequences. Furthermore, it clarifies why dentists (pediatric dentists in specific) should cooperate with other specialties to reduce expected consequences from continuing to adulthood.","PeriodicalId":16641,"journal":{"name":"Journal of Pain and Relief","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84728887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-06-03DOI: 10.4172/2167-0846.1000252
Dario Apuzzo, P. Ferrazza
Background: Migraine is a proceeding or an episodic neurological disorder characterized by recurrent headache, moderate to severe, often in association with a series of symptoms of autonomic nervous system. Approximately 14% of the population suffer from this pathology with a peak incidence between 25 and 55 years of age. In addition, headache is very common in children and adolescents, particularly among teenagers whose prevalence is estimated around 8-23%. Case results: This report focuses on two cases with recurrent migraine episodes, different for sex and age, that shows the effectiveness of oxygen-ozone therapy also using two different modalities of ozone administration. In both of the cases, a drastic reduction in the frequency and intensity of pain with a consequent reduction in disability and an improvement in some health-related quality of life aspects was observed. Discussion: A greater number of patients are required to establish the efficacy and tolerability of ozone therapy in headache disorder, for which it is intended a treatment with anti-inflammatory drugs, often also toxic and with adverse effects.
{"title":"Case Reports 0n Patients with Migraine Responding to Ozone Therapy","authors":"Dario Apuzzo, P. Ferrazza","doi":"10.4172/2167-0846.1000252","DOIUrl":"https://doi.org/10.4172/2167-0846.1000252","url":null,"abstract":"Background: Migraine is a proceeding or an episodic neurological disorder characterized by recurrent headache, moderate to severe, often in association with a series of symptoms of autonomic nervous system. Approximately 14% of the population suffer from this pathology with a peak incidence between 25 and 55 years of age. In addition, headache is very common in children and adolescents, particularly among teenagers whose prevalence is estimated around 8-23%. Case results: This report focuses on two cases with recurrent migraine episodes, different for sex and age, that shows the effectiveness of oxygen-ozone therapy also using two different modalities of ozone administration. In both of the cases, a drastic reduction in the frequency and intensity of pain with a consequent reduction in disability and an improvement in some health-related quality of life aspects was observed. Discussion: A greater number of patients are required to establish the efficacy and tolerability of ozone therapy in headache disorder, for which it is intended a treatment with anti-inflammatory drugs, often also toxic and with adverse effects.","PeriodicalId":16641,"journal":{"name":"Journal of Pain and Relief","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91526158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-06-03DOI: 10.4172/2167-0846.1000250
Melhuish Tm, White Ld
The concept of combined peri-operative strategies to manage analgesia after TKA has been discussed in the literature for more than two decades. The femoral nerve block (FNB) has long been considered the gold standard in post-TKA pain management by many, although other analgesic options have shown promise [1]. This year several significant articles have been released challenging this notion, investigating the efficacy of varied pain-management strategies.
{"title":"Peri-operative Strategies to Reduce Pain Post Total Knee Arthroplasty","authors":"Melhuish Tm, White Ld","doi":"10.4172/2167-0846.1000250","DOIUrl":"https://doi.org/10.4172/2167-0846.1000250","url":null,"abstract":"The concept of combined peri-operative strategies to manage analgesia after TKA has been discussed in the literature for more than two decades. The femoral nerve block (FNB) has long been considered the gold standard in post-TKA pain management by many, although other analgesic options have shown promise [1]. This year several significant articles have been released challenging this notion, investigating the efficacy of varied pain-management strategies.","PeriodicalId":16641,"journal":{"name":"Journal of Pain and Relief","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88912134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-26DOI: 10.4172/2167-0846.1000248
R. Gálvez-Valdovinos
Background: Acute gastric volvulus is a rare but potentially life-threatening cause of upper gastrointestinal obstruction. Therefore, emergency physicians must maintain a high index of suspicion when patients present signs and symptoms suggesting foregut occlusion. Surgical treatment of gastric volvulus, secondary to diaphragmatic eventration, can vary with no standard routines. In this communication, we discuss the value of a laparoscopic gastric sleeve to prevent recurrence.
{"title":"Laparoscopic Sleeve Gastrectomy as a Good Surgical Alternative in GastricVolvulus Caused by Diaphragmatic Eventration","authors":"R. Gálvez-Valdovinos","doi":"10.4172/2167-0846.1000248","DOIUrl":"https://doi.org/10.4172/2167-0846.1000248","url":null,"abstract":"Background: Acute gastric volvulus is a rare but potentially life-threatening cause of upper gastrointestinal obstruction. Therefore, emergency physicians must maintain a high index of suspicion when patients present signs and symptoms suggesting foregut occlusion. Surgical treatment of gastric volvulus, secondary to diaphragmatic eventration, can vary with no standard routines. In this communication, we discuss the value of a laparoscopic gastric sleeve to prevent recurrence.","PeriodicalId":16641,"journal":{"name":"Journal of Pain and Relief","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80540927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-20DOI: 10.4172/2167-0846.1000247
Y. Maiga, Z. Mamadou, M. Sangare, M. Sanou, S. Diallo, S. Diallo, M. Camara, Oumar Sidibé, Y. Sogoba, H. Traoré, J. Nizard
Objective: to report the epidemiological and clinical aspects, the therapeutic itinerary and impact of back pain on the quality of life of patients in the neurology department of CHU Gabriel Toure Mali. Patients and methods: this is a longitudinal study, conducted over 1 year. All patients seen in the department of Neurology, Gabriel Toure teaching hospital of Bamako with low back pain. Results: hospital frequency of low back pain was 9.94% with female predominance 58.3% vs. 41.7% for men, mean age 49.5 years, with a range from 20 to 79 years. The pattern of evolution of the disease was acute in 19.2% and chronic in 80.8%. In fact 45% of our patients come in first intention to a General Practitioners, the average duration of follow-up at the level of GP was 215 days. 56.8% of patients had stop working and the average duration was 12 days, the estimated annual financial cost was 223,551.79 Francs XOF e.g. 341.3 Euro. A significant impact of back pain on quality of life, leisure, anxiety and depression was noted in most of the patients using the DALLAS self questionnaire. Conclusion: Low back pain remains a frequent reason for consultation in neurology. Typical low back pain is the most frequent form. Management is multidisciplinary.
Pub Date : 2016-05-09DOI: 10.4172/2167-0846.1000246
T. Cho, K. Park
Complex regional pain syndrome (CRPS) is an inflammation-associated disorder which develops as a consequence of limb-confined trauma. The disease is characterized by spontaneous pain, swelling, skin color change, and movement disorder. Here, we report two cases studies on the remarkable amelioration of CRPS by the injections of placental extract into acupuncture points. A 59-year-old female patient with CRPS after 6 week-casting due to a fracture on the right metatarsal bone showed symptoms of severe pain, reddish skin color change, swelling, and restricted articular movement. Another 49-year-old female patient with CRPS after an arthroscopic surgery on the left ankle joint suffered from pricking pain, swelling, and movement restriction in the foot. Acupuncture points BL23, BL24, BL25, and LR4 localized on low back and ankle joint of both patients, were selected for application of placental extract. Both parents showed complete pain relief, swelling remission, redness disappearance, and articular movement restoration.
{"title":"Use of Acupuncture Point Injection with Placental Extract for Treatmentof Complex Regional Pain Syndrome","authors":"T. Cho, K. Park","doi":"10.4172/2167-0846.1000246","DOIUrl":"https://doi.org/10.4172/2167-0846.1000246","url":null,"abstract":"Complex regional pain syndrome (CRPS) is an inflammation-associated disorder which develops as a consequence of limb-confined trauma. The disease is characterized by spontaneous pain, swelling, skin color change, and movement disorder. Here, we report two cases studies on the remarkable amelioration of CRPS by the injections of placental extract into acupuncture points. A 59-year-old female patient with CRPS after 6 week-casting due to a fracture on the right metatarsal bone showed symptoms of severe pain, reddish skin color change, swelling, and restricted articular movement. Another 49-year-old female patient with CRPS after an arthroscopic surgery on the left ankle joint suffered from pricking pain, swelling, and movement restriction in the foot. Acupuncture points BL23, BL24, BL25, and LR4 localized on low back and ankle joint of both patients, were selected for application of placental extract. Both parents showed complete pain relief, swelling remission, redness disappearance, and articular movement restoration.","PeriodicalId":16641,"journal":{"name":"Journal of Pain and Relief","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83481577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-05DOI: 10.4172/2167-0846.1000245
D. Kopsky
The last 2 decades more and more attention has been given to topical analgesia. Peripheral nerves in the epidermis are influenced by topical analgesics with the aim to reduce neuropathic pain. Systemic side effects are rare, because the purpose of topical analgesics is not to penetrate deeper than the epidermis. Thus topical analgesics are particularly beneficial in the treatment of geriatric patients with high risk of undesirable side effects, drug interactions and altered metabolization due to intake of multiple medications. Even high concentrations of active compounds in topical analgesics do not give rise to serious side effects, such as ketamine cream up to 20% [1]. The absence of severe side effects most probably resides in the fact that the skin has its own metabolism for xenobiotic molecules [2]. Metabolism of ketamine occurs through various cytochrome P450s enzymes (CYP2B6, 2C9, 2C19, 3A4, 2A6, and 3A5), which are present in the epidermis [2].
{"title":"Topical analgesia is a viable option","authors":"D. Kopsky","doi":"10.4172/2167-0846.1000245","DOIUrl":"https://doi.org/10.4172/2167-0846.1000245","url":null,"abstract":"The last 2 decades more and more attention has been given to topical analgesia. Peripheral nerves in the epidermis are influenced by topical analgesics with the aim to reduce neuropathic pain. Systemic side effects are rare, because the purpose of topical analgesics is not to penetrate deeper than the epidermis. Thus topical analgesics are particularly beneficial in the treatment of geriatric patients with high risk of undesirable side effects, drug interactions and altered metabolization due to intake of multiple medications. Even high concentrations of active compounds in topical analgesics do not give rise to serious side effects, such as ketamine cream up to 20% [1]. The absence of severe side effects most probably resides in the fact that the skin has its own metabolism for xenobiotic molecules [2]. Metabolism of ketamine occurs through various cytochrome P450s enzymes (CYP2B6, 2C9, 2C19, 3A4, 2A6, and 3A5), which are present in the epidermis [2].","PeriodicalId":16641,"journal":{"name":"Journal of Pain and Relief","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74234846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-04-25DOI: 10.4172/2167-0846.1000244
A. Htun
This study was to evaluate the effect of an ilioinguinal-iliohypogastric nerve block with bupivacaine 0.25% on the postoperative analgesia and subsequent analgesic requirements in patients undergoing unilateral open inguinal herniorrhaphy under spinal anaesthesia. Fifty consenting American society of anaesthesiologists (ASA) score I-II patients scheduled for unilateral inguinal herniorrhaphy procedures were given spinal anaesthesia with hyperbaric 0.5% bupivacaine. In a randomized fashion, half of them received an ilioinguinal-iliohypogastric nerve block (IINB) with 30 millilitre (ml) of 0.25% bupivacaine at the time of wound closure and then other half with intramuscular injection of diclofenac sodium 75 milligram (mg). The patients were observed for postoperative 24 hour, such as duration of postoperative analgesia, first on demand analgesic and total analgesic doses, 4 hourly visual analogue scales (VAS), complications of nerve block, 4 hourly haemodynamic changes and assessed patient’s satisfaction at postoperative 12 hour in both groups. The results showed that in comparison with diclofenac group (group B), significantly longer duration of postoperative analgesia in IINB group (group A) (P<0.05%) and the amount required was also significantly less postoperatively in 24 hour (P<0.05%). No complications occurred. Patient’s satisfaction score at postoperative 12 hour was higher in group (A) patients (P<0.05%). There was no significant difference in haemodynamic changes between the two groups. It is concluded that the use of IINB with bupivacaine 0.25% at the time of wound closure in patients undergoing unilateral open inguinal herniorrhaphy under spinal anaesthesia decreased pain and analgesic requirements in the postoperative 24 hour and increased patient’s satisfaction score at postoperative 12 hour.
{"title":"A Study on Effectiveness of Ilioinguinal and Iliohypogastricnerve Block at the Time of Wound Closure for Postoperative Pain Relief in Inguinal Hernia Repair","authors":"A. Htun","doi":"10.4172/2167-0846.1000244","DOIUrl":"https://doi.org/10.4172/2167-0846.1000244","url":null,"abstract":"This study was to evaluate the effect of an ilioinguinal-iliohypogastric nerve block with bupivacaine 0.25% on the postoperative analgesia and subsequent analgesic requirements in patients undergoing unilateral open inguinal herniorrhaphy under spinal anaesthesia. Fifty consenting American society of anaesthesiologists (ASA) score I-II patients scheduled for unilateral inguinal herniorrhaphy procedures were given spinal anaesthesia with hyperbaric 0.5% bupivacaine. In a randomized fashion, half of them received an ilioinguinal-iliohypogastric nerve block (IINB) with 30 millilitre (ml) of 0.25% bupivacaine at the time of wound closure and then other half with intramuscular injection of diclofenac sodium 75 milligram (mg). The patients were observed for postoperative 24 hour, such as duration of postoperative analgesia, first on demand analgesic and total analgesic doses, 4 hourly visual analogue scales (VAS), complications of nerve block, 4 hourly haemodynamic changes and assessed patient’s satisfaction at postoperative 12 hour in both groups. The results showed that in comparison with diclofenac group (group B), significantly longer duration of postoperative analgesia in IINB group (group A) (P<0.05%) and the amount required was also significantly less postoperatively in 24 hour (P<0.05%). No complications occurred. Patient’s satisfaction score at postoperative 12 hour was higher in group (A) patients (P<0.05%). There was no significant difference in haemodynamic changes between the two groups. It is concluded that the use of IINB with bupivacaine 0.25% at the time of wound closure in patients undergoing unilateral open inguinal herniorrhaphy under spinal anaesthesia decreased pain and analgesic requirements in the postoperative 24 hour and increased patient’s satisfaction score at postoperative 12 hour.","PeriodicalId":16641,"journal":{"name":"Journal of Pain and Relief","volume":"10 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2016-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78798340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-04-18DOI: 10.4172/2167-0846.1000243
Phutsadee Pudchakan, K. Tanyasaensook, P. Chaudakshetrin, Penkae Ketumarn, C. Suthisisang
Background: Methadone is a synthetic opioid that is clinically effective in chronic pain management. However, the use of methadone is very limited in Thailand because physicians are not familiar with its dosing and are concerned about risks relating to drug accumulation and cardiac arrhythmias. Objective: The purpose of this study was to develop and implement a methadone protocol for patients with severe chronic pain in order to assure efficacy and safety of methadone. Methods: The protocol was developed based on published clinical studies and guidelines. The validated protocol was implemented in 34 patients at the Pain Clinic, Siriraj Hospital, Bangkok, Thailand. During the study period, pain score, pain interference score, neuropathic pain score, severity of adverse effects, and QTc intervals were investigated over a 3 month period. Results: The results obtained from 21 patients that completed the study showed a significant reduction in median pain intensity (p < 0.001) and other chronic pain interferences based on BPI-T (p < 0.001), excepted for the emotional score (p < 0.004) using methadone doses ranging from 2-30 mg daily. Neuropathic pain was also significantly reduced (p < 0.001). Common adverse effects were drowsiness (55.88%), constipation (35.29%), and nausea and/or vomiting (11.76%). Regarding ECG monitoring, seven patients without QTc prolongation at baseline developed QTc prolongation after methadone initiation. However, QTc interval greater than 500 msec or presentation of Torsades de Pointes were not found. No significant change in the mean QTc interval was observed after initiating methadone (p=0.951). Conclusion: Administration of methadone according to the protocol described in this study was found to be effective and safe for severe chronic pain management. ECG monitoring and drug interaction screening in patient treatment plan is advised when prescribing methadone.
{"title":"Evaluation of a Methadone Protocol for Severe Chronic Pain Management in Thai Patients: A Prospective Study","authors":"Phutsadee Pudchakan, K. Tanyasaensook, P. Chaudakshetrin, Penkae Ketumarn, C. Suthisisang","doi":"10.4172/2167-0846.1000243","DOIUrl":"https://doi.org/10.4172/2167-0846.1000243","url":null,"abstract":"Background: Methadone is a synthetic opioid that is clinically effective in chronic pain management. However, the use of methadone is very limited in Thailand because physicians are not familiar with its dosing and are concerned about risks relating to drug accumulation and cardiac arrhythmias. Objective: The purpose of this study was to develop and implement a methadone protocol for patients with severe chronic pain in order to assure efficacy and safety of methadone. Methods: The protocol was developed based on published clinical studies and guidelines. The validated protocol was implemented in 34 patients at the Pain Clinic, Siriraj Hospital, Bangkok, Thailand. During the study period, pain score, pain interference score, neuropathic pain score, severity of adverse effects, and QTc intervals were investigated over a 3 month period. Results: The results obtained from 21 patients that completed the study showed a significant reduction in median pain intensity (p < 0.001) and other chronic pain interferences based on BPI-T (p < 0.001), excepted for the emotional score (p < 0.004) using methadone doses ranging from 2-30 mg daily. Neuropathic pain was also significantly reduced (p < 0.001). Common adverse effects were drowsiness (55.88%), constipation (35.29%), and nausea and/or vomiting (11.76%). Regarding ECG monitoring, seven patients without QTc prolongation at baseline developed QTc prolongation after methadone initiation. However, QTc interval greater than 500 msec or presentation of Torsades de Pointes were not found. No significant change in the mean QTc interval was observed after initiating methadone (p=0.951). Conclusion: Administration of methadone according to the protocol described in this study was found to be effective and safe for severe chronic pain management. ECG monitoring and drug interaction screening in patient treatment plan is advised when prescribing methadone.","PeriodicalId":16641,"journal":{"name":"Journal of Pain and Relief","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89380390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-04-15DOI: 10.4172/2167-0846.1000242
D. Aufiero, S. Sampson, K. Onishi, Van Bemden Ab
1.1 Background: Epicondylitis is the second most frequently encountered head and upper limb musculoskeletal diagnosis in primary care clinics, with an incidence rate as high as 7/1,000 patients per year. Chronic or recalcitrant epicondylitis- more appropriately termed epicondylosis or elbow tendinosis- is not uncommon and represents a notable set of pathologies which account for lost recreation time, decreased quality of life, and workers compensation claims. A novel non-operative option has recently become available in the form of micronized dehydrated human amniotic/chorionic membrane (mDHACM) allograft. 1.2 Hypothesis: mDHACM allograft is known to be rich in anti-inflammatory cytokines and tissue inhibitors of metalloproteinase and IL-10. It also contains an abundance of growth factors and cytokines. In vivo and in vitro studies have shown reduction in scar tissue. We hypothesize that mDHACM allograft will be a viable treatment option in patients with epicondylosis. 1.3 Study design: Retrospective case series 1.4 Level of evidence: IV 1.5 Methods: Charts were retrospectively reviewed for 10 patients who received mDHACM allograft injections for treatment of medial or lateral epicondylosis.
{"title":"Treatment of Medial and Lateral Elbow Tendinosis with an Injectable Amniotic Membrane Allograft a retrospective case series","authors":"D. Aufiero, S. Sampson, K. Onishi, Van Bemden Ab","doi":"10.4172/2167-0846.1000242","DOIUrl":"https://doi.org/10.4172/2167-0846.1000242","url":null,"abstract":"1.1 Background: Epicondylitis is the second most frequently encountered head and upper limb musculoskeletal diagnosis in primary care clinics, with an incidence rate as high as 7/1,000 patients per year. Chronic or recalcitrant epicondylitis- more appropriately termed epicondylosis or elbow tendinosis- is not uncommon and represents a notable set of pathologies which account for lost recreation time, decreased quality of life, and workers compensation claims. A novel non-operative option has recently become available in the form of micronized dehydrated human amniotic/chorionic membrane (mDHACM) allograft. 1.2 Hypothesis: mDHACM allograft is known to be rich in anti-inflammatory cytokines and tissue inhibitors of metalloproteinase and IL-10. It also contains an abundance of growth factors and cytokines. In vivo and in vitro studies have shown reduction in scar tissue. We hypothesize that mDHACM allograft will be a viable treatment option in patients with epicondylosis. 1.3 Study design: Retrospective case series 1.4 Level of evidence: IV 1.5 Methods: Charts were retrospectively reviewed for 10 patients who received mDHACM allograft injections for treatment of medial or lateral epicondylosis.","PeriodicalId":16641,"journal":{"name":"Journal of Pain and Relief","volume":"2016 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80532959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：