首页 > 最新文献

Journal of Pediatric Orthopaedics最新文献

英文 中文
Reliability of a Modified Watson-Jones Classification for Tibial Tubercle Fractures in Children. 儿童胫骨结节骨折的改良 Watson-Jones 分类法的可靠性。
IF 1.4 3区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-01 Epub Date: 2024-07-01 DOI: 10.1097/BPO.0000000000002718
Taylor Bradley, Mary Crowe, Hani Mayassi, Jay Patel, Junichi Tamai, Charles T Mehlman

Objectives: The first case report describing a pediatric fracture of the tibial tubercle was published in 1852 in the Medical Times and Gazette, a Journal of Medical Science, literature, criticism, and news. A century later, in 1955, Sir Watson-Jones introduced the first classification system for this fracture. Despite the existence of several classification systems for pediatric tibial tubercle fractures in the medical literature, a crucial aspect of their validation-reliability and reproducibility-has not yet been systematically evaluated.

Methods: In this study, a modified Watson-Jones (mWJ) classification system of tibial tubercle fractures in children was assessed for intraobserver and interobserver variability. Using the mWJ classification, 3 board-certified pediatric orthopaedic surgeons and 3 orthopaedic surgery residents, classified thirty tibial tubercle fractures based on anteroposterior and lateral radiographs on 2 separate occasions in a 2-week duration. Further comparison was made to evaluate the impact of advanced imaging, specifically computed tomography or magnetic resonance imaging, on diagnostic reliability and reproducibility.

Results: The study found substantial intraobserver reliability of the mWJ classification based on radiographs alone, with a Cohen weighted kappa (κ w ) coefficient of 0.733. When advanced imaging was utilized, the reliability of the classification improved to κ w = 0.783. Similarly, interobserver reliability demonstrated substantial consistency among observers when using radiographs alone (κ w = 0.69) and improved agreement with advanced imaging (κ w = 0.75). Notably, there was no significant difference in reliability scores between senior-level attendings and residents when analyzed as separate groups.

Conclusion: Fracture classification systems are clinically relevant tools that help organize and transfer knowledge efficiently, provide treatment guidance, propose prognostic expectations, and improve communication in academic literature. The present study demonstrated substantial reproducibility of an mWJ fracture classification system both between and within individual surgeon raters.

Level of evidence: Level III-diagnostic.

目的:第一份描述小儿胫骨结节骨折的病例报告发表于 1852 年的《医学时代与公报》(Medical Times and Gazette),这是一份关于医学科学、文学、批评和新闻的杂志。一个世纪后的1955年,沃森-琼斯爵士首次提出了这种骨折的分类系统。尽管医学文献中存在多种小儿胫骨结节骨折分类系统,但其验证的一个重要方面--可靠性和可重复性--尚未得到系统评估:在这项研究中,对儿童胫骨结节骨折的改良Watson-Jones(mWJ)分类系统进行了观察者内和观察者间变异性评估。通过使用 mWJ 分类法,3 位获得认证的小儿骨科外科医生和 3 位骨科住院医师在 2 周的时间内,根据前后位和侧位 X 光片对 30 例胫骨结节骨折进行了分类。研究还进一步比较评估了先进成像技术(特别是计算机断层扫描或磁共振成像)对诊断可靠性和可重复性的影响:研究发现,仅根据X光片进行的mWJ分类在观察者内部具有很高的可靠性,科恩加权卡帕(κw)系数为0.733。当采用先进的成像技术时,分类的可靠性提高到了 κw = 0.783。同样,观察者之间的可靠性在仅使用射线照相时表现出很大的一致性(κw = 0.69),而在使用高级成像技术时,一致性则有所提高(κw = 0.75)。值得注意的是,将高级主治医师和住院医师作为不同组别进行分析时,两者的可靠性评分没有明显差异:结论:骨折分类系统是与临床相关的工具,有助于有效地组织和传递知识,提供治疗指导,提出预后预期,并改善学术文献的交流。本研究表明,mWJ 骨折分类系统在外科医生个体之间和个体内部都具有很强的可重复性:证据等级:三级诊断。
{"title":"Reliability of a Modified Watson-Jones Classification for Tibial Tubercle Fractures in Children.","authors":"Taylor Bradley, Mary Crowe, Hani Mayassi, Jay Patel, Junichi Tamai, Charles T Mehlman","doi":"10.1097/BPO.0000000000002718","DOIUrl":"10.1097/BPO.0000000000002718","url":null,"abstract":"<p><strong>Objectives: </strong>The first case report describing a pediatric fracture of the tibial tubercle was published in 1852 in the Medical Times and Gazette, a Journal of Medical Science, literature, criticism, and news. A century later, in 1955, Sir Watson-Jones introduced the first classification system for this fracture. Despite the existence of several classification systems for pediatric tibial tubercle fractures in the medical literature, a crucial aspect of their validation-reliability and reproducibility-has not yet been systematically evaluated.</p><p><strong>Methods: </strong>In this study, a modified Watson-Jones (mWJ) classification system of tibial tubercle fractures in children was assessed for intraobserver and interobserver variability. Using the mWJ classification, 3 board-certified pediatric orthopaedic surgeons and 3 orthopaedic surgery residents, classified thirty tibial tubercle fractures based on anteroposterior and lateral radiographs on 2 separate occasions in a 2-week duration. Further comparison was made to evaluate the impact of advanced imaging, specifically computed tomography or magnetic resonance imaging, on diagnostic reliability and reproducibility.</p><p><strong>Results: </strong>The study found substantial intraobserver reliability of the mWJ classification based on radiographs alone, with a Cohen weighted kappa (κ w ) coefficient of 0.733. When advanced imaging was utilized, the reliability of the classification improved to κ w = 0.783. Similarly, interobserver reliability demonstrated substantial consistency among observers when using radiographs alone (κ w = 0.69) and improved agreement with advanced imaging (κ w = 0.75). Notably, there was no significant difference in reliability scores between senior-level attendings and residents when analyzed as separate groups.</p><p><strong>Conclusion: </strong>Fracture classification systems are clinically relevant tools that help organize and transfer knowledge efficiently, provide treatment guidance, propose prognostic expectations, and improve communication in academic literature. The present study demonstrated substantial reproducibility of an mWJ fracture classification system both between and within individual surgeon raters.</p><p><strong>Level of evidence: </strong>Level III-diagnostic.</p>","PeriodicalId":16945,"journal":{"name":"Journal of Pediatric Orthopaedics","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141492395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in Fracture Shortening Occur in the First 2 Weeks Following Completely Displaced Adolescent Clavicle Fractures. 青少年锁骨完全移位骨折后的头两周内,骨折缩短发生变化。
IF 1.4 3区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-01 Epub Date: 2024-05-07 DOI: 10.1097/BPO.0000000000002724
Crystal A Perkins, Jeffrey J Nepple, Joshua H Pang, Michael T Busch, Eric W Edmonds, Henry B Ellis, Mininder S Kocher, Ying Li, Nirav K Pandya, Andrew T Pennock, Coleen S Sabatini, David D Spence, Samuel C Willimon, Philip L Wilson, Benton E Heyworth

Background: Shortening of midshaft clavicle fractures has been described as a critical fracture characteristic to guide treatment. The degree to which shortening may change in the initial weeks following injury has not been well studied. The purpose of this study was to evaluate the change in shortening of adolescent clavicle fractures in the first 2 weeks following injury.

Methods: This was a multicenter study of prospectively collected data, which was acquired as a part of a cohort study of adolescent clavicle fractures. A consecutive series of patients 10 to 18 years of age with completely displaced diaphyseal clavicle fractures with baseline radiographs 0 to 6 days from the date of injury, as well as 7 to 21 days from the date of injury, were included. Measurements of end-to-end (EES) and cortex-to-corresponding-cortex (CCS) shortening were performed.

Results: A total of 142 patients were included. Baseline radiographs were obtained at a mean of 1.0 day following injury with mean EES of 22.3 mm, and 69% of patients demonstrating > 20 mm of shortening. Follow-up radiographs obtained at a mean of 13.8 days postinjury demonstrated a mean absolute change in EES of 5.4 mm. Forty-one percentage of patients had >5 mm of change in EES. When analyzing changes in shortening relative to the specific threshold of 20 mm, 18 patients (41%) with <20 mm EES increased to ≥20 mm EES, and 19 patients (19%) with ≥20 mm EES decreased to <20 mm EES at 2-week follow-up.

Conclusions: Clinically significant changes in fracture shortening occurred in 41% of adolescents with completely displaced clavicle fractures in the first 2 weeks after injury. In 26% of patients, this resulted in a change from above or below the commonly used shortening threshold of 20 mm, potentially altering the treatment plan by many providers. There is no evidence to suggest that adolescent clavicle fracture shortening affects outcomes, and as such, the authors do not advocate for the use of this parameter to guide treatment. However, among physicians who continue to use this parameter to guide treatment, this study supports that repeat radiographic assessment 2 weeks postinjury may be a better measure of the true shortening of this common adolescent injury.

Level of evidence: Level IV-case series.

背景:锁骨中轴骨折的缩短被认为是指导治疗的关键骨折特征。关于受伤后最初几周缩短程度的变化尚未得到充分研究。本研究旨在评估青少年锁骨骨折在伤后两周内缩短度的变化:这是一项前瞻性数据收集的多中心研究,是青少年锁骨骨折队列研究的一部分。研究对象为年龄在10至18岁的锁骨骨折完全移位患者,这些患者的基线X光片检查时间为受伤后0至6天,以及受伤后7至21天。对端对端(EES)和皮质对相应皮质(CCS)的缩短量进行了测量:结果:共纳入 142 名患者。在受伤后平均 1.0 天获得基线射线照相,平均 EES 为 22.3 毫米,69% 的患者显示缩短>20 毫米。伤后平均 13.8 天的随访X光片显示,EES 的平均绝对值变化为 5.4 毫米。41%的患者 EES 的变化大于 5 毫米。在分析相对于 20 毫米这一特定阈值的缩短变化时,18 名患者(41%)得出结论:41%的锁骨完全移位骨折青少年在伤后两周内骨折缩短度发生了明显的临床变化。在26%的患者中,这种变化导致骨折缩短量高于或低于常用的20毫米阈值,这可能会改变许多医疗机构的治疗方案。没有证据表明青少年锁骨骨折缩短会影响治疗效果,因此作者不主张使用这一参数来指导治疗。不过,在继续使用该参数指导治疗的医生中,本研究支持伤后两周重复放射学评估可能更能衡量这种常见青少年损伤的真正缩短程度:证据等级:IV级-病例系列。
{"title":"Changes in Fracture Shortening Occur in the First 2 Weeks Following Completely Displaced Adolescent Clavicle Fractures.","authors":"Crystal A Perkins, Jeffrey J Nepple, Joshua H Pang, Michael T Busch, Eric W Edmonds, Henry B Ellis, Mininder S Kocher, Ying Li, Nirav K Pandya, Andrew T Pennock, Coleen S Sabatini, David D Spence, Samuel C Willimon, Philip L Wilson, Benton E Heyworth","doi":"10.1097/BPO.0000000000002724","DOIUrl":"10.1097/BPO.0000000000002724","url":null,"abstract":"<p><strong>Background: </strong>Shortening of midshaft clavicle fractures has been described as a critical fracture characteristic to guide treatment. The degree to which shortening may change in the initial weeks following injury has not been well studied. The purpose of this study was to evaluate the change in shortening of adolescent clavicle fractures in the first 2 weeks following injury.</p><p><strong>Methods: </strong>This was a multicenter study of prospectively collected data, which was acquired as a part of a cohort study of adolescent clavicle fractures. A consecutive series of patients 10 to 18 years of age with completely displaced diaphyseal clavicle fractures with baseline radiographs 0 to 6 days from the date of injury, as well as 7 to 21 days from the date of injury, were included. Measurements of end-to-end (EES) and cortex-to-corresponding-cortex (CCS) shortening were performed.</p><p><strong>Results: </strong>A total of 142 patients were included. Baseline radiographs were obtained at a mean of 1.0 day following injury with mean EES of 22.3 mm, and 69% of patients demonstrating > 20 mm of shortening. Follow-up radiographs obtained at a mean of 13.8 days postinjury demonstrated a mean absolute change in EES of 5.4 mm. Forty-one percentage of patients had >5 mm of change in EES. When analyzing changes in shortening relative to the specific threshold of 20 mm, 18 patients (41%) with <20 mm EES increased to ≥20 mm EES, and 19 patients (19%) with ≥20 mm EES decreased to <20 mm EES at 2-week follow-up.</p><p><strong>Conclusions: </strong>Clinically significant changes in fracture shortening occurred in 41% of adolescents with completely displaced clavicle fractures in the first 2 weeks after injury. In 26% of patients, this resulted in a change from above or below the commonly used shortening threshold of 20 mm, potentially altering the treatment plan by many providers. There is no evidence to suggest that adolescent clavicle fracture shortening affects outcomes, and as such, the authors do not advocate for the use of this parameter to guide treatment. However, among physicians who continue to use this parameter to guide treatment, this study supports that repeat radiographic assessment 2 weeks postinjury may be a better measure of the true shortening of this common adolescent injury.</p><p><strong>Level of evidence: </strong>Level IV-case series.</p>","PeriodicalId":16945,"journal":{"name":"Journal of Pediatric Orthopaedics","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140874686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Body Mass Index on Pedobarographic and Patient-Reported Outcome Measures in Adolescent Flexible Flat Feet. 身体质量指数对青少年柔性扁平足足底摄影和患者报告结果测量的影响。
IF 1.4 3区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-01 Epub Date: 2024-05-06 DOI: 10.1097/BPO.0000000000002720
Victoria Blackwood, Kelly A Jeans, Jacob R Zide, Anthony I Riccio

Background: Although adolescent flexible flatfoot deformity (FFD) is common, little is known regarding the effect of weight on associated symptomatology. This study uses pedobarography and patient-reported outcome measures (PROs) to determine if overweight adolescents with FFD have more severe alterations in dynamic plantar pressures than normal body mass index percentiles (wnBMI) with FFD and if such alterations correlate with pain and activity.

Methods: A retrospective review of patients aged 10 to 18 years with nonsyndromic symptomatic FFD was performed. Overweight (BMI percentile ≥ 85%) patients were compared with wnBMI patients with regard to dynamic plantar pressure measures and PRO scores. Pedobarographic data were subdivided into regions: medial/lateral hindfoot and midfoot, and first, second, and third to fifth metatarsals. Plantar pressure variables were normalized to account for differences in foot size, body weight, and walking speed. Contact area (CA%), maximum force by body weight (MF%), and contact time as a percentage of the rollover process (CT%) were calculated. Two foot-specific PROs were assessed, including the Foot and Ankle Outcome Score and the Oxford Ankle Foot Measure for Children.

Results: Of the 48 adolescents studied, 27 (56%) were overweight and 21 (44%) were wnBMI. After normalization of the data, overweight patients had significantly greater medial midfoot MF%, whereas CT% was increased across the medial and lateral midfoot and hindfoot regions. Correlations showed positive trends: as BMI percentile increases, so will CA and MF in the medial midfoot, as well as CT in the medial and lateral midfoot and hindfoot. Significant differences were seen between groups, with the overweight group reporting lower sports and recreation subscores than the wnBMI group. No significant differences were seen in the pain and disability subscores.

Conclusions: Although overweight adolescents with FFD exhibit greater forces and more time spent during the rollover process in the medial midfoot than normal-weight patients, they did not report worse pain or disability associated with their flat foot deformity.

Level of evidence: Therapeutic level 3.

背景:虽然青少年柔性扁平足畸形(FFD)很常见,但人们对体重对相关症状的影响知之甚少。本研究采用足底照相术和患者报告结果测量法(PROs)来确定患有FFD的超重青少年是否比患有FFD的正常体重指数百分位数(wnBMI)青少年的动态足底压力有更严重的改变,以及这种改变是否与疼痛和活动相关:方法: 我们对 10 至 18 岁非综合征症状性 FFD 患者进行了回顾性研究。在动态足底压力测量和PRO评分方面,超重(BMI百分位数≥85%)患者与wnBMI患者进行了比较。足底照相数据按区域细分:后足内侧/外侧和中足,以及第一、第二和第三至第五跖骨。足底压力变量经过归一化处理,以考虑足部大小、体重和行走速度的差异。计算了接触面积(CA%)、按体重计算的最大力(MF%)和接触时间占翻滚过程的百分比(CT%)。还评估了两个足部特异性PRO,包括足踝结果评分(Foot and Ankle Outcome Score)和牛津儿童踝足测量(Oxford Ankle Foot Measure for Children):在接受研究的 48 名青少年中,27 人(56%)超重,21 人(44%)体重超标。在对数据进行归一化处理后,超重患者的中足内侧MF%明显增加,而中足内侧、外侧和后足区域的CT%均有所增加。相关性呈正趋势:随着体重指数百分位数的增加,中足内侧的CA和MF以及中足内侧、外侧和后足的CT也会增加。各组之间存在显著差异,超重组的运动和娱乐分项得分低于肥胖组。在疼痛和残疾子评分方面没有发现明显差异:尽管患有扁平足畸形的超重青少年比体重正常的患者在足内侧翻滚过程中表现出更大的力量和花费更多的时间,但他们并没有报告扁平足畸形导致更严重的疼痛或残疾:证据等级:治疗 3 级。
{"title":"Effect of Body Mass Index on Pedobarographic and Patient-Reported Outcome Measures in Adolescent Flexible Flat Feet.","authors":"Victoria Blackwood, Kelly A Jeans, Jacob R Zide, Anthony I Riccio","doi":"10.1097/BPO.0000000000002720","DOIUrl":"10.1097/BPO.0000000000002720","url":null,"abstract":"<p><strong>Background: </strong>Although adolescent flexible flatfoot deformity (FFD) is common, little is known regarding the effect of weight on associated symptomatology. This study uses pedobarography and patient-reported outcome measures (PROs) to determine if overweight adolescents with FFD have more severe alterations in dynamic plantar pressures than normal body mass index percentiles (wnBMI) with FFD and if such alterations correlate with pain and activity.</p><p><strong>Methods: </strong>A retrospective review of patients aged 10 to 18 years with nonsyndromic symptomatic FFD was performed. Overweight (BMI percentile ≥ 85%) patients were compared with wnBMI patients with regard to dynamic plantar pressure measures and PRO scores. Pedobarographic data were subdivided into regions: medial/lateral hindfoot and midfoot, and first, second, and third to fifth metatarsals. Plantar pressure variables were normalized to account for differences in foot size, body weight, and walking speed. Contact area (CA%), maximum force by body weight (MF%), and contact time as a percentage of the rollover process (CT%) were calculated. Two foot-specific PROs were assessed, including the Foot and Ankle Outcome Score and the Oxford Ankle Foot Measure for Children.</p><p><strong>Results: </strong>Of the 48 adolescents studied, 27 (56%) were overweight and 21 (44%) were wnBMI. After normalization of the data, overweight patients had significantly greater medial midfoot MF%, whereas CT% was increased across the medial and lateral midfoot and hindfoot regions. Correlations showed positive trends: as BMI percentile increases, so will CA and MF in the medial midfoot, as well as CT in the medial and lateral midfoot and hindfoot. Significant differences were seen between groups, with the overweight group reporting lower sports and recreation subscores than the wnBMI group. No significant differences were seen in the pain and disability subscores.</p><p><strong>Conclusions: </strong>Although overweight adolescents with FFD exhibit greater forces and more time spent during the rollover process in the medial midfoot than normal-weight patients, they did not report worse pain or disability associated with their flat foot deformity.</p><p><strong>Level of evidence: </strong>Therapeutic level 3.</p>","PeriodicalId":16945,"journal":{"name":"Journal of Pediatric Orthopaedics","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140864098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two AIS Cases, 2 Surgeons, 1 Operating Room, 1 Day: Faster and Safer Than 1 Case in a Day. 两个 AIS 病例、两名外科医生、一间手术室、一天时间:比一天一个病例更快、更安全。
IF 1.4 3区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-01 Epub Date: 2024-06-17 DOI: 10.1097/BPO.0000000000002716
Jonathan R Warren, Robert C Link, Sean Bonanni, McKenna C Noe, John T Anderson, Richard M Schwend

Background: To lessen surgical times for patients with adolescent idiopathic scoliosis (AIS) undergoing posterior spinal instrumentation and fusion (PSIF), our department developed a quality improvement initiative where 2 AIS cases were completed in 1 day by the same 2 surgeons operating together in 1 operating room (OR). We describe the results of this initiative, comparing operative times and outcomes to cases of these surgeons operating individually.

Methods: From 2017 to 2023, patients aged 10 to 18 years with AIS undergoing PSIF were prospectively enrolled for "Two Spine Tuesday." Patients were matched by age, sex, curve severity, and number of levels fused to historical AIS controls. Outcomes included surgery time, total OR time, estimated blood loss (EBL), volume of cell saver transfused, allogenic blood transfusion, length of stay, 90-day readmissions, Clavien-Dindo-Sink Complication Classification System complication rates, and percentage who achieved the minimal clinically important difference (MCID) for SRS-22.

Results: Fifty-five patients composing the 2-spine group (group 2) were compared with 55 historical sex-matched and age-matched controls (group 1). Major coronal curve and average number of levels fused were similar between groups. Overall surgery time (203 vs. 296 min, P <0.001), total OR time ( P <0.001), and EBL (400 vs. 550 mL, P <0.001) were lower for group 2. Group 2 had fewer complications [n=17 (31%) vs. n=28 (51%), P =0.03].

Conclusions: Performing 2 AIS cases in 1 OR by 2 surgeons the same day resulted in shorter surgery times, less total time in the operating room, lower complication rates, and less blood loss compared with single-surgeon matched controls.

Level of evidence: Level III-retrospective comparative study.

背景:为了缩短青少年特发性脊柱侧凸(AIS)患者接受脊柱后路器械和融合术(PSIF)的手术时间,我们科室制定了一项质量改进计划,由同两名外科医生在一间手术室(OR)内共同完成2例AIS患者的手术。我们描述了这一举措的结果,并将手术时间和结果与这些外科医生单独手术的病例进行了比较:从 2017 年到 2023 年,接受 PSIF 手术的 10 至 18 岁 AIS 患者被前瞻性地纳入 "双脊柱星期二"。患者的年龄、性别、曲线严重程度和融合水平数与历史 AIS 对照组相匹配。结果包括手术时间、手术室总时间、估计失血量(EBL)、输注的细胞保存液量、异体输血、住院时间、90天再住院率、Clavien-Dindo-Sink并发症分类系统并发症发生率以及SRS-22达到最小临床重要差异(MCID)的百分比:双脊柱组(第2组)的55名患者与55名性别匹配、年龄匹配的历史对照组(第1组)进行了比较。两组患者的主要冠状曲线和平均融合水平数相似。总体手术时间(203 分钟对 296 分钟,PC 结论:在一个手术室中进行 2 个 AIS 病例的手术时间为 296 分钟:与单个外科医生匹配的对照组相比,由两名外科医生在同一天在一个手术室进行 2 例 AIS 手术,手术时间更短,在手术室的总时间更短,并发症发生率更低,失血量更少:证据等级:III 级--回顾性比较研究。
{"title":"Two AIS Cases, 2 Surgeons, 1 Operating Room, 1 Day: Faster and Safer Than 1 Case in a Day.","authors":"Jonathan R Warren, Robert C Link, Sean Bonanni, McKenna C Noe, John T Anderson, Richard M Schwend","doi":"10.1097/BPO.0000000000002716","DOIUrl":"10.1097/BPO.0000000000002716","url":null,"abstract":"<p><strong>Background: </strong>To lessen surgical times for patients with adolescent idiopathic scoliosis (AIS) undergoing posterior spinal instrumentation and fusion (PSIF), our department developed a quality improvement initiative where 2 AIS cases were completed in 1 day by the same 2 surgeons operating together in 1 operating room (OR). We describe the results of this initiative, comparing operative times and outcomes to cases of these surgeons operating individually.</p><p><strong>Methods: </strong>From 2017 to 2023, patients aged 10 to 18 years with AIS undergoing PSIF were prospectively enrolled for \"Two Spine Tuesday.\" Patients were matched by age, sex, curve severity, and number of levels fused to historical AIS controls. Outcomes included surgery time, total OR time, estimated blood loss (EBL), volume of cell saver transfused, allogenic blood transfusion, length of stay, 90-day readmissions, Clavien-Dindo-Sink Complication Classification System complication rates, and percentage who achieved the minimal clinically important difference (MCID) for SRS-22.</p><p><strong>Results: </strong>Fifty-five patients composing the 2-spine group (group 2) were compared with 55 historical sex-matched and age-matched controls (group 1). Major coronal curve and average number of levels fused were similar between groups. Overall surgery time (203 vs. 296 min, P <0.001), total OR time ( P <0.001), and EBL (400 vs. 550 mL, P <0.001) were lower for group 2. Group 2 had fewer complications [n=17 (31%) vs. n=28 (51%), P =0.03].</p><p><strong>Conclusions: </strong>Performing 2 AIS cases in 1 OR by 2 surgeons the same day resulted in shorter surgery times, less total time in the operating room, lower complication rates, and less blood loss compared with single-surgeon matched controls.</p><p><strong>Level of evidence: </strong>Level III-retrospective comparative study.</p>","PeriodicalId":16945,"journal":{"name":"Journal of Pediatric Orthopaedics","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141331191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In-office Maximal Voluntary Ventilation Testing Demonstrates Pulmonary Improvement Following Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis. 诊室内最大自主通气测试显示青少年特发性脊柱侧凸后路脊柱融合术后肺功能改善。
IF 1.4 3区 医学 Q3 ORTHOPEDICS Pub Date : 2024-09-01 Epub Date: 2024-08-07 DOI: 10.1097/BPO.0000000000002694
Hulaimatu Jalloh, Lindsay M Andras, Greg Redding, Gabriela A Villamor, Joshua Yang, David L Skaggs

Objective: Pulmonary function can be impaired in patients with adolescent idiopathic scoliosis (AIS). Maximal voluntary ventilation (MVV) has been shown to be more strongly correlated with major coronal curve, and a more easily obtained measurement of pulmonary function, than forced vital capacity (FVC). We evaluated changes in pulmonary function using these 2 measures in patients with AIS in relation to changes in major coronal curves over time.

Methods: Forty-seven patients with AIS with thoracic curves ≥10 degrees performed pulmonary function tests using the Carefusion MicroLoop Spirometer at enrollment and 1 year later. Major coronal curve worsening >5 degrees was considered curve progression.

Results: At enrollment, 47 patients had a mean major coronal curve of 38 degrees (range: 10 to 76 degrees). One year later, 17 patients had undergone posterior spinal fusion, 9 had curve progression >5 degrees, and 21 had no progression. MVV and major coronal curve were negatively correlated (r = -0.36, P = 0.01) at enrollment. After fusion, the major coronal curve improved by a mean of 41 degrees, and MVV improved by 23% (P < 0.01), but FVC did not improve significantly (6%, P = 0.29). In stable curves, MVV improved 12% (P = 0.01) and FVC improved 9% (P = 0.007). In patients without surgery whose curves progressed an average of 11 degrees, there was no significant change in MVV or FVC (P > 0.44).

Conclusion: This is the first study using office-based spirometry in an orthopaedic clinic showing improved pulmonary function with posterior spinal fusion and growth in patients with AIS. It is notable that MVV improved after spinal fusion, but FVC did not, as MVV appears to be a more sensitive measurement for the assessment of pulmonary function in these patients.

Level of evidence: Level II.

目的:青少年特发性脊柱侧弯症(AIS)患者的肺功能可能会受损。研究表明,最大自主通气量(MVV)与主要冠状曲线的相关性更强,而且比用力肺活量(FVC)更容易测量肺功能。我们使用这两种测量方法评估了 AIS 患者肺功能的变化与主要冠状曲线随时间变化的关系:47名胸廓曲线≥10度的AIS患者在入院时和1年后使用Carefusion MicroLoop肺活量计进行了肺功能测试。主要冠状曲线恶化>5度被视为曲线进展:入组时,47 名患者的主要冠状曲线平均为 38 度(范围:10 至 76 度)。一年后,17 名患者接受了脊柱后路融合术,9 名患者的曲线恶化程度大于 5 度,21 名患者的曲线没有恶化。入院时,MVV 与主要冠状曲线呈负相关(r = -0.36,P = 0.01)。融合术后,主要冠状曲线平均改善了 41 度,肺活量改善了 23%(P < 0.01),但肺活量改善不明显(6%,P = 0.29)。在曲线稳定的患者中,肺活量提高了 12% (P = 0.01),肺活量提高了 9% (P = 0.007)。在未接受手术的患者中,其曲线平均发展了 11 度,但 MVV 或 FVC 没有显著变化(P > 0.44):结论:这是第一项在骨科诊所使用诊室肺活量测定法进行的研究,结果显示后路脊柱融合术改善了 AIS 患者的肺功能。值得注意的是,脊柱融合术后 MVV 有所改善,但 FVC 没有改善,因为 MVV 似乎是评估这些患者肺功能的更灵敏的测量方法:证据等级:二级。
{"title":"In-office Maximal Voluntary Ventilation Testing Demonstrates Pulmonary Improvement Following Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis.","authors":"Hulaimatu Jalloh, Lindsay M Andras, Greg Redding, Gabriela A Villamor, Joshua Yang, David L Skaggs","doi":"10.1097/BPO.0000000000002694","DOIUrl":"https://doi.org/10.1097/BPO.0000000000002694","url":null,"abstract":"<p><strong>Objective: </strong>Pulmonary function can be impaired in patients with adolescent idiopathic scoliosis (AIS). Maximal voluntary ventilation (MVV) has been shown to be more strongly correlated with major coronal curve, and a more easily obtained measurement of pulmonary function, than forced vital capacity (FVC). We evaluated changes in pulmonary function using these 2 measures in patients with AIS in relation to changes in major coronal curves over time.</p><p><strong>Methods: </strong>Forty-seven patients with AIS with thoracic curves ≥10 degrees performed pulmonary function tests using the Carefusion MicroLoop Spirometer at enrollment and 1 year later. Major coronal curve worsening >5 degrees was considered curve progression.</p><p><strong>Results: </strong>At enrollment, 47 patients had a mean major coronal curve of 38 degrees (range: 10 to 76 degrees). One year later, 17 patients had undergone posterior spinal fusion, 9 had curve progression >5 degrees, and 21 had no progression. MVV and major coronal curve were negatively correlated (r = -0.36, P = 0.01) at enrollment. After fusion, the major coronal curve improved by a mean of 41 degrees, and MVV improved by 23% (P < 0.01), but FVC did not improve significantly (6%, P = 0.29). In stable curves, MVV improved 12% (P = 0.01) and FVC improved 9% (P = 0.007). In patients without surgery whose curves progressed an average of 11 degrees, there was no significant change in MVV or FVC (P > 0.44).</p><p><strong>Conclusion: </strong>This is the first study using office-based spirometry in an orthopaedic clinic showing improved pulmonary function with posterior spinal fusion and growth in patients with AIS. It is notable that MVV improved after spinal fusion, but FVC did not, as MVV appears to be a more sensitive measurement for the assessment of pulmonary function in these patients.</p><p><strong>Level of evidence: </strong>Level II.</p>","PeriodicalId":16945,"journal":{"name":"Journal of Pediatric Orthopaedics","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141897697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Comparison of ChatGPT and Expert Consensus Statements on Surgical Site Infection Prevention in High-Risk Paediatric Spine Surgery. 高风险儿科脊柱手术中手术部位感染预防的 ChatGPT 和专家共识声明比较。
IF 1.4 3区 医学 Q3 ORTHOPEDICS Pub Date : 2024-08-30 DOI: 10.1097/BPO.0000000000002781
Aaron N Chester, Shay I Mandler

Background: Artificial intelligence (AI) represents and exciting shift for orthopaedic surgery, where its role is rapidly evolving. ChatGPT is an AI language model which is preeminent among those leading the mass consumer uptake of AI. Artamonov and colleagues compared ChatGPT with orthopaedic surgeons when considering the diagnosis and management of anterior shoulder instability; they found a limited correlation between them. This study aims to further explore how reliable ChatGPT is compared with orthopaedic surgeons.

Methods: Twenty-three statements were extracted from the article "Building Consensus: Development of a Best Practice Guideline (BPG) for Surgical Site Infection (SSI) Prevention in High-risk Pediatric Spine Surgery" by Vitale and colleagues. These included 14 consensus statements and an additional 9 statements that did not reach consensus. ChatGPT was asked to state the extent to which it agreed with each statement.

Results: ChatGPT appeared to demonstrate a fair correlation with most expert responses to the 14 consensus statements. It appeared less emphatic than the experts, often stating that it "agreed" with a statement, where the most frequent response from experts was "strongly agree." It reached the opposite conclusion to the majority of experts on a single consensus statement regarding the use of ultraviolet light in the operating theatre; it may have been that ChatGPT was drawing from more up to date literature that was published subsequent to the consensus statement.

Conclusions: This study demonstrated a reasonable correlation between ChatGPT and orthopaedic surgeons when providing simple responses. ChatGPT's function may be limited when asked to provide more complex answers. This study adds to a growing body of discussion and evidence exploring AI and whether its function is reliable enough to enter the high-accountability world of health care.

Clinical relevance: This article is of high clinical relevance to orthopaedic surgery given the rapidly emerging applications of AI. This creates a need to understand the level to which AI can function in the clinical setting and the risks that would entail.

背景:人工智能(AI)对骨科手术来说是一个令人兴奋的转变,其作用正在迅速发展。ChatGPT 是一种人工智能语言模型,在引领消费者大规模使用人工智能方面处于领先地位。Artamonov 及其同事将 ChatGPT 与骨科医生在考虑肩关节前方不稳定的诊断和管理时进行了比较;他们发现两者之间的相关性有限。本研究旨在进一步探讨 ChatGPT 与骨科医生相比的可靠性:方法:从 "建立共识:最佳实践指南的制定(Best Practice Guideline)"一文中摘录了 23 项声明:Vitale 及其同事撰写的文章《建立共识:制定高风险小儿脊柱手术中预防手术部位感染 (SSI) 的最佳实践指南 (BPG)》中摘录了 23 项声明。其中包括 14 项共识声明和另外 9 项未达成共识的声明。ChatGPT 被要求说明其同意每项声明的程度:结果:ChatGPT 似乎与大多数专家对 14 项共识声明的回应有相当的相关性。它似乎没有专家那么强调,经常表示 "同意 "某项声明,而专家最常见的回答是 "非常同意"。在一项关于手术室使用紫外线的共识声明中,ChatGPT 得出了与大多数专家相反的结论;这可能是因为 ChatGPT 采用的是共识声明之后发表的最新文献:本研究表明,ChatGPT 和骨科医生在提供简单回答时具有合理的相关性。当要求提供更复杂的答案时,ChatGPT 的功能可能会受到限制。这项研究为探讨人工智能及其功能是否足够可靠以进入高问责的医疗保健领域的讨论和证据增加了新的内容:鉴于人工智能的应用正在迅速兴起,这篇文章与骨科手术具有高度的临床相关性。因此,我们有必要了解人工智能在临床环境中发挥作用的程度以及可能带来的风险。
{"title":"A Comparison of ChatGPT and Expert Consensus Statements on Surgical Site Infection Prevention in High-Risk Paediatric Spine Surgery.","authors":"Aaron N Chester, Shay I Mandler","doi":"10.1097/BPO.0000000000002781","DOIUrl":"https://doi.org/10.1097/BPO.0000000000002781","url":null,"abstract":"<p><strong>Background: </strong>Artificial intelligence (AI) represents and exciting shift for orthopaedic surgery, where its role is rapidly evolving. ChatGPT is an AI language model which is preeminent among those leading the mass consumer uptake of AI. Artamonov and colleagues compared ChatGPT with orthopaedic surgeons when considering the diagnosis and management of anterior shoulder instability; they found a limited correlation between them. This study aims to further explore how reliable ChatGPT is compared with orthopaedic surgeons.</p><p><strong>Methods: </strong>Twenty-three statements were extracted from the article \"Building Consensus: Development of a Best Practice Guideline (BPG) for Surgical Site Infection (SSI) Prevention in High-risk Pediatric Spine Surgery\" by Vitale and colleagues. These included 14 consensus statements and an additional 9 statements that did not reach consensus. ChatGPT was asked to state the extent to which it agreed with each statement.</p><p><strong>Results: </strong>ChatGPT appeared to demonstrate a fair correlation with most expert responses to the 14 consensus statements. It appeared less emphatic than the experts, often stating that it \"agreed\" with a statement, where the most frequent response from experts was \"strongly agree.\" It reached the opposite conclusion to the majority of experts on a single consensus statement regarding the use of ultraviolet light in the operating theatre; it may have been that ChatGPT was drawing from more up to date literature that was published subsequent to the consensus statement.</p><p><strong>Conclusions: </strong>This study demonstrated a reasonable correlation between ChatGPT and orthopaedic surgeons when providing simple responses. ChatGPT's function may be limited when asked to provide more complex answers. This study adds to a growing body of discussion and evidence exploring AI and whether its function is reliable enough to enter the high-accountability world of health care.</p><p><strong>Clinical relevance: </strong>This article is of high clinical relevance to orthopaedic surgery given the rapidly emerging applications of AI. This creates a need to understand the level to which AI can function in the clinical setting and the risks that would entail.</p>","PeriodicalId":16945,"journal":{"name":"Journal of Pediatric Orthopaedics","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term Outcomes of Intramedullary Nails in Osteogenesis Imperfecta: Fewer Surgeries and Longer Survival Times With Telescoping Rods in Patients With Over Ten Years Follow-up. 髓内钉治疗成骨不全症的长期疗效:在超过十年的随访中,使用伸缩杆的患者手术次数更少、存活时间更长。
IF 1.4 3区 医学 Q3 ORTHOPEDICS Pub Date : 2024-08-30 DOI: 10.1097/BPO.0000000000002810
Cynthia V Nguyen, Christopher A Makarewich, Selina C Poon, Robert H Cho, Theresa A Hennessey

Objective: Intramedullary rodding of lower extremity long bones in patients with osteogenesis imperfecta (OI) is a widely accepted technique for fracture treatment and prevention. Previous small studies with short to medium-term follow-up have shown that telescoping rods have longer survival times compared with static rods. However, there are no long-term studies (10 or more years) longitudinally evaluating the results of these procedures. The purpose of this study was to compare the rod survival duration and number of procedures in patients treated with static versus telescoping rods with 10 years minimum follow-up.

Methods: This was a multicenter retrospective comparative study of patients with a diagnosis of OI who had intramedullary nailing of the femur and/or tibia. Each bone included in the study had a 10-year minimum follow-up, only one type of rod utilized over the follow-up period, and no rod replacement surgeries outside of the primary hospital system. Patient demographics, clinical data, and details of each procedure were obtained. Groups were compared using univariate analysis with a 2-independent samples t test for continuous variables, χ2 for categorical variables, and the Kaplan-Meier method for survival analysis.

Results: A total of 119 bones in 52 patients met inclusion criteria. Average follow up was 13.1 (range: 10.2 to 18.4) years. There were no differences between groups in follow-up length, Sillence type, bisphosphonate use, or age at first-rod placement. There were significantly more tibias treated in the static rod group compared with the telescopic rod group. The average survival length was significantly longer for telescopic rods, 5.8 ± 3.9 years versus 4.0±3.6 years for static rods. On average, bones treated with telescopic rods had significantly fewer surgeries compared with static rods (2.2 ± 0.8 vs 3.3 ± 1.6).

Conclusion: At long term follow up, bone segments in patients with OI treated with telescopic rods required fewer surgeries and had longer implant survival times compared with those treated with static rods. When available, surgeons should consider telescopic rods as the initial implant choice in this patient population.

目的:对成骨不全症(OI)患者的下肢长骨进行髓内植骨是一种广为接受的骨折治疗和预防技术。以往中短期随访的小型研究表明,伸缩杆与静态杆相比存活时间更长。然而,目前还没有长期(10 年或更长时间)的纵向研究对这些手术的结果进行评估。本研究的目的是比较使用静态和伸缩牙棒治疗的患者的牙棒存活时间和手术次数,至少随访 10 年:这是一项多中心回顾性比较研究,研究对象是确诊为OI并接受股骨和/或胫骨髓内钉治疗的患者。研究中的每块骨头都有至少10年的随访期,随访期间只使用一种类型的钢棒,并且没有在主要医院系统外进行钢棒更换手术。研究人员了解了患者的人口统计学特征、临床数据以及每项手术的详细情况。采用单变量分析和双独立样本 t 检验对连续变量进行分组比较,χ2 检验对分类变量进行分组比较,Kaplan-Meier 法对生存率进行分析:共有 52 名患者的 119 块骨骼符合纳入标准。平均随访时间为 13.1 年(范围:10.2 至 18.4 年)。各组在随访时间、Sillence类型、使用双膦酸盐或首次置入骨棒的年龄方面没有差异。与伸缩杆组相比,静态杆组治疗的胫骨明显更多。伸缩杆的平均存活时间明显更长,为 5.8 ± 3.9 年,而静态杆为 4.0 ± 3.6 年。使用伸缩杆治疗的骨骼平均手术次数明显少于静态杆(2.2 ± 0.8 vs 3.3 ± 1.6):在长期随访中,与使用静态杆治疗的患者相比,使用伸缩杆治疗的 OI 患者骨段所需的手术次数更少,植入物存活时间更长。在条件允许的情况下,外科医生应考虑将伸缩杆作为此类患者的初始植入选择。
{"title":"Long-term Outcomes of Intramedullary Nails in Osteogenesis Imperfecta: Fewer Surgeries and Longer Survival Times With Telescoping Rods in Patients With Over Ten Years Follow-up.","authors":"Cynthia V Nguyen, Christopher A Makarewich, Selina C Poon, Robert H Cho, Theresa A Hennessey","doi":"10.1097/BPO.0000000000002810","DOIUrl":"https://doi.org/10.1097/BPO.0000000000002810","url":null,"abstract":"<p><strong>Objective: </strong>Intramedullary rodding of lower extremity long bones in patients with osteogenesis imperfecta (OI) is a widely accepted technique for fracture treatment and prevention. Previous small studies with short to medium-term follow-up have shown that telescoping rods have longer survival times compared with static rods. However, there are no long-term studies (10 or more years) longitudinally evaluating the results of these procedures. The purpose of this study was to compare the rod survival duration and number of procedures in patients treated with static versus telescoping rods with 10 years minimum follow-up.</p><p><strong>Methods: </strong>This was a multicenter retrospective comparative study of patients with a diagnosis of OI who had intramedullary nailing of the femur and/or tibia. Each bone included in the study had a 10-year minimum follow-up, only one type of rod utilized over the follow-up period, and no rod replacement surgeries outside of the primary hospital system. Patient demographics, clinical data, and details of each procedure were obtained. Groups were compared using univariate analysis with a 2-independent samples t test for continuous variables, χ2 for categorical variables, and the Kaplan-Meier method for survival analysis.</p><p><strong>Results: </strong>A total of 119 bones in 52 patients met inclusion criteria. Average follow up was 13.1 (range: 10.2 to 18.4) years. There were no differences between groups in follow-up length, Sillence type, bisphosphonate use, or age at first-rod placement. There were significantly more tibias treated in the static rod group compared with the telescopic rod group. The average survival length was significantly longer for telescopic rods, 5.8 ± 3.9 years versus 4.0±3.6 years for static rods. On average, bones treated with telescopic rods had significantly fewer surgeries compared with static rods (2.2 ± 0.8 vs 3.3 ± 1.6).</p><p><strong>Conclusion: </strong>At long term follow up, bone segments in patients with OI treated with telescopic rods required fewer surgeries and had longer implant survival times compared with those treated with static rods. When available, surgeons should consider telescopic rods as the initial implant choice in this patient population.</p>","PeriodicalId":16945,"journal":{"name":"Journal of Pediatric Orthopaedics","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Clubfoot and Neonatal Abstinence Syndrome in the United States, 2018-2022. 2018-2022 年美国马蹄内翻足与新生儿戒断综合征之间的关系。
IF 1.4 3区 医学 Q3 ORTHOPEDICS Pub Date : 2024-08-30 DOI: 10.1097/BPO.0000000000002798
Meera M Dhodapkar, Anshu Jonnalagadda, Adrienne R Socci, Corinna Franklin

Purpose: The United States has seen an increase in opioid use and misuse over the last 2 decades. Infants have been impacted by the opioid epidemic, with a reported 5-fold increase in the incidence of neonatal abstinence syndrome (NAS) over the last 2 decades. There are many conditions associated with NAS, and thus, the current study sought to examine the association between NAS and clubfoot.

Methods: The study was retrospective, utilizing patient data from the Pediatric Hospital Information System (PHIS) database. Neonates presenting to any PHIS hospital between 2018 and 2022 were identified and included in the study. Patients with NAS and clubfoot were identified utilizing the International Classification of Diseases (ICD)-9 and 10 codes. Univariable and multivariable analyses were performed to investigate associations between clubfoot, race, ethnicity, insurance type, gestational age, length of stay, NAS, and comorbidity burden.

Results: A total of 458,274 patients were identified, of whom 2337 (0.5%) had a clubfoot diagnosis and 5431 (1.2%) had a diagnosis of NAS. Multivariable logistic regression revealed higher independent odds of clubfoot among patients with a diagnosis of NAS [odds ratio (OR): 1.49], patients with a greater number of comorbidities (OR: 4.75 for 1 comorbidity vs. none, and 21.19 for 2+ comorbidities, vs. none), patients with a greater gestational age (OR: 1.01 per week increase), and those with an increased length of stay (OR: 1.00 per day increase). A lower independent odds of clubfoot was observed among patients of Asian race (OR: 0.66), Hispanic/Latino ethnicity (OR: 0.80), non-Hispanic Black (OR: 0.75), and multiracial (OR: 0.80) ethnicity/race relative to non-Hispanic/Latino White patients (P<0.05 for all).

Conclusion: Patients with a diagnosis of NAS demonstrated higher odds of clubfoot, in addition to sociodemographic factors, as well as comorbidity burden.

目的:在过去 20 年中,美国阿片类药物的使用和滥用有所增加。婴儿也受到了阿片类药物流行的影响,据报道,在过去 20 年中,新生儿禁欲综合征(NAS)的发病率增加了 5 倍。与NAS相关的疾病有很多,因此,本研究试图探讨NAS与足癣之间的关系:本研究是一项回顾性研究,利用的是儿科医院信息系统(PHIS)数据库中的患者数据。2018年至2022年期间在任何一家PHIS医院就诊的新生儿均被确定并纳入研究。利用国际疾病分类(ICD)-9和10代码确定NAS和马蹄内翻足患者。研究人员进行了单变量和多变量分析,以调查足癣、种族、民族、保险类型、妊娠年龄、住院时间、NAS和合并症负担之间的关联:共发现 458 274 名患者,其中 2337 人(0.5%)确诊为马蹄内翻足,5431 人(1.2%)确诊为 NAS。多变量逻辑回归显示,诊断为NAS的患者[几率比(OR):1.49]、合并症较多的患者(1种合并症与无合并症相比,OR:4.75;2种以上合并症与无合并症相比,OR:21.19)、胎龄较大的患者(OR:每增加一周增加1.01)和住院时间较长的患者(OR:每增加一天增加1.00)发生马蹄内翻足的独立几率较高。与非西班牙裔/拉美裔白人患者相比,亚洲人种(OR:0.66)、西班牙裔/拉美裔人种(OR:0.80)、非西班牙裔黑人(OR:0.75)和多种族(OR:0.80)人种/人种的患者发生足外翻的几率较低(PConclusion:除社会人口因素和合并症负担外,诊断为NAS的患者患足癣的几率更高。
{"title":"Association Between Clubfoot and Neonatal Abstinence Syndrome in the United States, 2018-2022.","authors":"Meera M Dhodapkar, Anshu Jonnalagadda, Adrienne R Socci, Corinna Franklin","doi":"10.1097/BPO.0000000000002798","DOIUrl":"https://doi.org/10.1097/BPO.0000000000002798","url":null,"abstract":"<p><strong>Purpose: </strong>The United States has seen an increase in opioid use and misuse over the last 2 decades. Infants have been impacted by the opioid epidemic, with a reported 5-fold increase in the incidence of neonatal abstinence syndrome (NAS) over the last 2 decades. There are many conditions associated with NAS, and thus, the current study sought to examine the association between NAS and clubfoot.</p><p><strong>Methods: </strong>The study was retrospective, utilizing patient data from the Pediatric Hospital Information System (PHIS) database. Neonates presenting to any PHIS hospital between 2018 and 2022 were identified and included in the study. Patients with NAS and clubfoot were identified utilizing the International Classification of Diseases (ICD)-9 and 10 codes. Univariable and multivariable analyses were performed to investigate associations between clubfoot, race, ethnicity, insurance type, gestational age, length of stay, NAS, and comorbidity burden.</p><p><strong>Results: </strong>A total of 458,274 patients were identified, of whom 2337 (0.5%) had a clubfoot diagnosis and 5431 (1.2%) had a diagnosis of NAS. Multivariable logistic regression revealed higher independent odds of clubfoot among patients with a diagnosis of NAS [odds ratio (OR): 1.49], patients with a greater number of comorbidities (OR: 4.75 for 1 comorbidity vs. none, and 21.19 for 2+ comorbidities, vs. none), patients with a greater gestational age (OR: 1.01 per week increase), and those with an increased length of stay (OR: 1.00 per day increase). A lower independent odds of clubfoot was observed among patients of Asian race (OR: 0.66), Hispanic/Latino ethnicity (OR: 0.80), non-Hispanic Black (OR: 0.75), and multiracial (OR: 0.80) ethnicity/race relative to non-Hispanic/Latino White patients (P<0.05 for all).</p><p><strong>Conclusion: </strong>Patients with a diagnosis of NAS demonstrated higher odds of clubfoot, in addition to sociodemographic factors, as well as comorbidity burden.</p>","PeriodicalId":16945,"journal":{"name":"Journal of Pediatric Orthopaedics","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aspirations Dashed: Conventional Synovial Fluid Analysis Is Superior to Synovial Fluid and Blood Neutrophil-to-Lymphocyte Ratios in Diagnosing Pediatric Septic Arthritis of the Hip and Knee. 愿望破灭:在诊断小儿髋关节和膝关节化脓性关节炎方面,传统滑膜液分析优于滑膜液和血液中性粒细胞与淋巴细胞比率。
IF 1.4 3区 医学 Q3 ORTHOPEDICS Pub Date : 2024-08-30 DOI: 10.1097/BPO.0000000000002785
Christopher J DeFrancesco, David P VanEenenaam, Carter E Hall, Vineet M Desai, Kevin Orellana, Wudbhav N Sankar
<p><strong>Introduction: </strong>Recent research suggests that synovial fluid neutrophil-to-lymphocyte ratio (SF-NLR) is a superior diagnostic for pyogenic septic arthritis (SA) in adults compared with synovial fluid white blood cell count (SF-WBC) ≥50,000 cells/μL or ≥90% polymorphonuclear leukocytes (SF-%PMN). Other research also indicates that the neutrophil-to-lymphocyte ratio in the blood (B-NLR) may be of diagnostic significance. However, it is not known whether these findings extend to the pediatric population.</p><p><strong>Methods: </strong>Medical records at a large urban tertiary-care children's hospital were queried for emergency department visits between 2012 and 2023, where synovial fluid (SF) analysis was performed to evaluate for SA of the hip or knee. Patients 18 years old and above were excluded. The "conventional composite test" (CCT) for SA was considered positive if SF analysis showed any of the following: (1) SF-WBC ≥50,000 cells/μL, (2) ≥90% PMNs, or (3) organisms reported on gram stain. Patients with aspirate and/or operating room (OR) cultures (or supplemental testing, ie, nucleic acid identification) revealing an offending organism were considered to have culture-positive septic arthritis (CPSA). The remaining patients were considered culture-negative (CN). Serum and SF test data were analyzed to assess their diagnostic utility in identifying CPSA. Receiver operating characteristic (ROC) curves were examined to compare the predictive value of SF-NLR and B-NLR versus conventional indicators of SA.</p><p><strong>Results: </strong>A total of 394 patients met the inclusion criteria. In all, 58.6% (n=231) were male, 67.5% (n=266) involved the knee, and 20.1% (n=79) had CPSA. Those with CPSA had higher ESR and CRP compared with CN patients (P<0.01). Bivariate testing did not show a difference in SF-NLR or B-NLR between those with CPSA and CN patients (P=0.93 and 0.37, respectively). The CCT showed 91% sensitivity and 35% specificity using conventional thresholds. ROC analysis showed that SF-WBC was superior to SF-NLR and B-NLR in the diagnosis of CPSA (AUC=0.71 vs. 0.50 and 0.53, respectively; both P<0.01). Among CCT (+) patients who ended up culture negative, Lyme testing was positive in 48.8% (100/205).</p><p><strong>Conclusion: </strong>In contrast to adults, SF-NLR and B-NLR were not found to be strong diagnostic indicators of SA of the hip or knee in pediatric patients. This may be because competing diagnoses in children come with systemic inflammatory responses similar to that seen in pyogenic SA, while noninfectious conditions that might represent the major alternate diagnoses in adults do not increase systemic inflammatory markers as significantly. Given the high incidence of Lyme disease seen among patients in this study, this topic should be further studied at pediatric centers outside Lyme-endemic areas to better understand the generalizability of these findings.</p><p><strong>Significance: </strong>Despite excitem
导言:最新研究表明,与滑膜液白细胞计数(SF-WBC)≥50,000 个/μL 或多形核白细胞≥90%(SF-%PMN)相比,滑膜液中性粒细胞与淋巴细胞比值(SF-NLR)对成人化脓性关节炎(SA)的诊断效果更佳。其他研究也表明,血液中的中性粒细胞与淋巴细胞比率(B-NLR)可能具有诊断意义。然而,这些研究结果是否适用于儿科人群尚不得而知:方法: 我们查询了一家大型城市三级儿童医院 2012 年至 2023 年间的急诊就诊病历,并对这些病历进行了滑液 (SF) 分析,以评估髋关节或膝关节是否存在 SA。不包括 18 岁及以上的患者。如果滑液分析显示以下任何一种情况,SA 的 "常规复合检验"(CCT)即被视为阳性:(1) SF-WBC ≥50,000个细胞/μL,(2) PMN≥90%,或 (3) 革兰氏染色显示有微生物。吸出物和/或手术室(OR)培养(或补充检测,即核酸鉴定)显示有病原体的患者被视为培养阳性脓毒性关节炎(CPSA)。其余患者被视为培养阴性(CN)。对血清和 SF 检测数据进行了分析,以评估它们在鉴别 CPSA 方面的诊断效用。研究了接收者操作特征曲线(ROC),以比较 SF-NLR 和 B-NLR 与 SA 传统指标的预测价值:共有 394 名患者符合纳入标准。其中,58.6%(n=231)为男性,67.5%(n=266)累及膝关节,20.1%(n=79)患有 CPSA。与 CN 患者相比,CPSA 患者的 ESR 和 CRP 较高:与成人相比,SF-NLR 和 B-NLR 并非儿科患者髋关节或膝关节 SA 的有力诊断指标。这可能是因为儿童的竞争性诊断伴随着与化脓性 SA 类似的全身炎症反应,而可能代表成人主要替代诊断的非感染性疾病不会显著增加全身炎症指标。鉴于本研究中莱姆病患者的高发病率,应在莱姆病流行地区以外的儿科中心进一步研究这一课题,以更好地了解这些发现的普遍性:意义:尽管SF-NLR和B-NLR作为成人SA的诊断标准引起了广泛关注,但这些标准在莱姆病流行地区儿科患者化脓性SA的诊断中似乎作用不大。
{"title":"Aspirations Dashed: Conventional Synovial Fluid Analysis Is Superior to Synovial Fluid and Blood Neutrophil-to-Lymphocyte Ratios in Diagnosing Pediatric Septic Arthritis of the Hip and Knee.","authors":"Christopher J DeFrancesco, David P VanEenenaam, Carter E Hall, Vineet M Desai, Kevin Orellana, Wudbhav N Sankar","doi":"10.1097/BPO.0000000000002785","DOIUrl":"https://doi.org/10.1097/BPO.0000000000002785","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Recent research suggests that synovial fluid neutrophil-to-lymphocyte ratio (SF-NLR) is a superior diagnostic for pyogenic septic arthritis (SA) in adults compared with synovial fluid white blood cell count (SF-WBC) ≥50,000 cells/μL or ≥90% polymorphonuclear leukocytes (SF-%PMN). Other research also indicates that the neutrophil-to-lymphocyte ratio in the blood (B-NLR) may be of diagnostic significance. However, it is not known whether these findings extend to the pediatric population.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Medical records at a large urban tertiary-care children's hospital were queried for emergency department visits between 2012 and 2023, where synovial fluid (SF) analysis was performed to evaluate for SA of the hip or knee. Patients 18 years old and above were excluded. The \"conventional composite test\" (CCT) for SA was considered positive if SF analysis showed any of the following: (1) SF-WBC ≥50,000 cells/μL, (2) ≥90% PMNs, or (3) organisms reported on gram stain. Patients with aspirate and/or operating room (OR) cultures (or supplemental testing, ie, nucleic acid identification) revealing an offending organism were considered to have culture-positive septic arthritis (CPSA). The remaining patients were considered culture-negative (CN). Serum and SF test data were analyzed to assess their diagnostic utility in identifying CPSA. Receiver operating characteristic (ROC) curves were examined to compare the predictive value of SF-NLR and B-NLR versus conventional indicators of SA.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 394 patients met the inclusion criteria. In all, 58.6% (n=231) were male, 67.5% (n=266) involved the knee, and 20.1% (n=79) had CPSA. Those with CPSA had higher ESR and CRP compared with CN patients (P&lt;0.01). Bivariate testing did not show a difference in SF-NLR or B-NLR between those with CPSA and CN patients (P=0.93 and 0.37, respectively). The CCT showed 91% sensitivity and 35% specificity using conventional thresholds. ROC analysis showed that SF-WBC was superior to SF-NLR and B-NLR in the diagnosis of CPSA (AUC=0.71 vs. 0.50 and 0.53, respectively; both P&lt;0.01). Among CCT (+) patients who ended up culture negative, Lyme testing was positive in 48.8% (100/205).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;In contrast to adults, SF-NLR and B-NLR were not found to be strong diagnostic indicators of SA of the hip or knee in pediatric patients. This may be because competing diagnoses in children come with systemic inflammatory responses similar to that seen in pyogenic SA, while noninfectious conditions that might represent the major alternate diagnoses in adults do not increase systemic inflammatory markers as significantly. Given the high incidence of Lyme disease seen among patients in this study, this topic should be further studied at pediatric centers outside Lyme-endemic areas to better understand the generalizability of these findings.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Significance: &lt;/strong&gt;Despite excitem","PeriodicalId":16945,"journal":{"name":"Journal of Pediatric Orthopaedics","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes Following Surgery for Congenital Dislocation of Knee: Comment on the Study by Honcharuk et al. 先天性膝关节脱位手术后的疗效:对 Honcharuk 等人研究的评论
IF 1.4 3区 医学 Q3 ORTHOPEDICS Pub Date : 2024-08-29 DOI: 10.1097/BPO.0000000000002807
Sitanshu Barik, Sumit Raghute
{"title":"Outcomes Following Surgery for Congenital Dislocation of Knee: Comment on the Study by Honcharuk et al.","authors":"Sitanshu Barik, Sumit Raghute","doi":"10.1097/BPO.0000000000002807","DOIUrl":"https://doi.org/10.1097/BPO.0000000000002807","url":null,"abstract":"","PeriodicalId":16945,"journal":{"name":"Journal of Pediatric Orthopaedics","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142093579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Pediatric Orthopaedics
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1