Pub Date : 2024-09-18DOI: 10.1080/15287394.2024.2401382
Pablo Echeverria Macedo, Jéssica Eduarda Santos Batista, Lorena Raspanti Souza, Alcir Luiz Dafre, Marcelo Farina, Kamil Kuca, Thais Posser, Paulo Marcos Pinto, Juliano Tomazzoni Boldo, Jeferson Luis Franco
The widely used insecticide chlorpyrifos (CP) is known to inhibit acetylcholinesterase (AChE) activity attributed to result in various neurological disorders and acetylcholine-dependent organ funct...
{"title":"Drosophila melanogaster as a model organism for screening acetylcholinesterase reactivators","authors":"Pablo Echeverria Macedo, Jéssica Eduarda Santos Batista, Lorena Raspanti Souza, Alcir Luiz Dafre, Marcelo Farina, Kamil Kuca, Thais Posser, Paulo Marcos Pinto, Juliano Tomazzoni Boldo, Jeferson Luis Franco","doi":"10.1080/15287394.2024.2401382","DOIUrl":"https://doi.org/10.1080/15287394.2024.2401382","url":null,"abstract":"The widely used insecticide chlorpyrifos (CP) is known to inhibit acetylcholinesterase (AChE) activity attributed to result in various neurological disorders and acetylcholine-dependent organ funct...","PeriodicalId":17418,"journal":{"name":"Journal of Toxicology and Environmental Health, Part A","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142268069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-06DOI: 10.1080/15287394.2024.2387041
Ji Won Park, Jae Hyeon Park, Haeun Lee, Cong Wang, Shugeng Cao, Hyung Sik Kim
Ultraviolet-B (UVB) radiation is a major physical factor that induces structural changes in human skin. The aim of this study was to determine whether the novel silent information regulator 1 (sirt...
{"title":"Penilumamide, a novel SIRT1 activator, protects UVB-induced photodamages in HaCaT cells","authors":"Ji Won Park, Jae Hyeon Park, Haeun Lee, Cong Wang, Shugeng Cao, Hyung Sik Kim","doi":"10.1080/15287394.2024.2387041","DOIUrl":"https://doi.org/10.1080/15287394.2024.2387041","url":null,"abstract":"Ultraviolet-B (UVB) radiation is a major physical factor that induces structural changes in human skin. The aim of this study was to determine whether the novel silent information regulator 1 (sirt...","PeriodicalId":17418,"journal":{"name":"Journal of Toxicology and Environmental Health, Part A","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141940753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-29DOI: 10.1080/15287394.2024.2346938
Kristine Krajnak, Mariana Farcas, Diana Richardson, Mary Anne Hammer, Stacey Waugh, Walter McKinney, Alycia Knepp, Mark Jackson, Dru Burns, Ryan LeBouf, Joanna Matheson, Treye Thomas, Yong Qian
Three-dimensional (3D) printing with polycarbonate (PC) plastic occurs in manufacturing settings, homes, and schools. Emissions generated during printing with PC stock and bisphenol-A (BPA), an end...
使用聚碳酸酯（PC）塑料进行三维（3D）打印的情况在生产环境、家庭和学校中时有发生。在使用 PC 涂料和双酚 A (BPA) 进行打印的过程中会产生废气，而双酚 A 是一种...
{"title":"Exposure to emissions generated by 3-dimensional printing with polycarbonate: effects on peripheral vascular function, cardiac vascular morphology and expression of markers of oxidative stress in male rat cardiac tissue","authors":"Kristine Krajnak, Mariana Farcas, Diana Richardson, Mary Anne Hammer, Stacey Waugh, Walter McKinney, Alycia Knepp, Mark Jackson, Dru Burns, Ryan LeBouf, Joanna Matheson, Treye Thomas, Yong Qian","doi":"10.1080/15287394.2024.2346938","DOIUrl":"https://doi.org/10.1080/15287394.2024.2346938","url":null,"abstract":"Three-dimensional (3D) printing with polycarbonate (PC) plastic occurs in manufacturing settings, homes, and schools. Emissions generated during printing with PC stock and bisphenol-A (BPA), an end...","PeriodicalId":17418,"journal":{"name":"Journal of Toxicology and Environmental Health, Part A","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140810690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-15DOI: 10.1080/15287394.2024.2340069
Glaucia Cristina de Lima e Souza Mesquita, Elkejer Ribeiro Da Cruz, Dione Silva Corrêa, Alexandre de Barros Falcão Ferraz, Jéssica Machado Miri, Ingrid Vicente Farias, Flávio Henrique Reginatto, Fernanda Brião Menezes Boaretto, Duani Maria dos Santos, Juliana da Silva, Ivana Grivicich, Jaqueline Nascimento Picada
The bark extract from Endopleura uchi has been widely used in traditional medicine to treat gynecological-related disorders, diabetes, and dyslipidemias albeit without scientific proof. In addition...
{"title":"Genotoxic and antiproliferative properties of Endopleura uchi bark aqueous extract","authors":"Glaucia Cristina de Lima e Souza Mesquita, Elkejer Ribeiro Da Cruz, Dione Silva Corrêa, Alexandre de Barros Falcão Ferraz, Jéssica Machado Miri, Ingrid Vicente Farias, Flávio Henrique Reginatto, Fernanda Brião Menezes Boaretto, Duani Maria dos Santos, Juliana da Silva, Ivana Grivicich, Jaqueline Nascimento Picada","doi":"10.1080/15287394.2024.2340069","DOIUrl":"https://doi.org/10.1080/15287394.2024.2340069","url":null,"abstract":"The bark extract from Endopleura uchi has been widely used in traditional medicine to treat gynecological-related disorders, diabetes, and dyslipidemias albeit without scientific proof. In addition...","PeriodicalId":17418,"journal":{"name":"Journal of Toxicology and Environmental Health, Part A","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140568553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-15DOI: 10.1080/15287394.2024.2338431
Ricardo Gomes dos Santos Nunes, Luciclaudio Cassimiro de Amorim, Iverson Conrado Bezerra, Artur José da Silva, Carlos Alonso Leite dos Santos, Priscila Gubert, Irwin Rose Alencar de Menezesa, Antonia Eliene Duarte, Luiz Marivando Barros, Belmira Lara da Silveira Andrade-da-Costa, Márcia Vanusa dos Santos, Maria Tereza dos Santos Correia, Michelle Melgarejo da Rosa
One prominent aspect of Parkinson’s disease (PD) is the presence of elevated levels of free radicals, including reactive oxygen species (ROS). Syagrus coronata (S. coronata), a palm tree, exhibits ...
{"title":"Syagrus coronata fixed oil prevents rotenone-induced movement disorders and oxidative stress in Drosophila melanogaster","authors":"Ricardo Gomes dos Santos Nunes, Luciclaudio Cassimiro de Amorim, Iverson Conrado Bezerra, Artur José da Silva, Carlos Alonso Leite dos Santos, Priscila Gubert, Irwin Rose Alencar de Menezesa, Antonia Eliene Duarte, Luiz Marivando Barros, Belmira Lara da Silveira Andrade-da-Costa, Márcia Vanusa dos Santos, Maria Tereza dos Santos Correia, Michelle Melgarejo da Rosa","doi":"10.1080/15287394.2024.2338431","DOIUrl":"https://doi.org/10.1080/15287394.2024.2338431","url":null,"abstract":"One prominent aspect of Parkinson’s disease (PD) is the presence of elevated levels of free radicals, including reactive oxygen species (ROS). Syagrus coronata (S. coronata), a palm tree, exhibits ...","PeriodicalId":17418,"journal":{"name":"Journal of Toxicology and Environmental Health, Part A","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140568551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-09DOI: 10.1080/15287394.2024.2338914
Bing-Qian Ma, Jian-Xin Jia, He Wang, Si-Jia Li, Zhan-Jun Yang, Xin-Xin Wang, Xu-Sheng Yan
Cannabidiol (CBD), a natural component extracted from Cannabis sativa L. exerts neuroprotective, antioxidant, and anti-inflammatory effects in Alzheimer’s disease (AD), a disease characterized by i...
{"title":"Cannabidiol improves the cognitive function of SAMP8 AD model mice involving the microbiota-gut-brain axis","authors":"Bing-Qian Ma, Jian-Xin Jia, He Wang, Si-Jia Li, Zhan-Jun Yang, Xin-Xin Wang, Xu-Sheng Yan","doi":"10.1080/15287394.2024.2338914","DOIUrl":"https://doi.org/10.1080/15287394.2024.2338914","url":null,"abstract":"Cannabidiol (CBD), a natural component extracted from Cannabis sativa L. exerts neuroprotective, antioxidant, and anti-inflammatory effects in Alzheimer’s disease (AD), a disease characterized by i...","PeriodicalId":17418,"journal":{"name":"Journal of Toxicology and Environmental Health, Part A","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140568828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-09DOI: 10.1080/15287394.2024.2339538
Osayimwen Imade, Bobola V. Ilesanmi, Germaine O. Ogunwole, Olusola O. Elekofehinti, Marília Cristina Oliveira Souza, Fernando Barbosa, Chris O. Adedire, Joseph A. Adeyemi
The toxic effects of 2, 4-dichlorophenol (2, 4-DCP) on aquatic organisms are well-established; however, the details regarding the mechanisms underlying the toxicity, especially immunotoxicity are p...
{"title":"Effects of 2,4-dichlorophenol on non–specific immunity, histopathological lesions, and redox balance in African Catfish, clarias gariepinus (Burchell, 1822)","authors":"Osayimwen Imade, Bobola V. Ilesanmi, Germaine O. Ogunwole, Olusola O. Elekofehinti, Marília Cristina Oliveira Souza, Fernando Barbosa, Chris O. Adedire, Joseph A. Adeyemi","doi":"10.1080/15287394.2024.2339538","DOIUrl":"https://doi.org/10.1080/15287394.2024.2339538","url":null,"abstract":"The toxic effects of 2, 4-dichlorophenol (2, 4-DCP) on aquatic organisms are well-established; however, the details regarding the mechanisms underlying the toxicity, especially immunotoxicity are p...","PeriodicalId":17418,"journal":{"name":"Journal of Toxicology and Environmental Health, Part A","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140568435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-04DOI: 10.1080/15287394.2024.2337366
Andressa Rubim Lopes, Dennis Guilherme Costa Silva, Nathane Rosa Rodrigues, Illana Kemmerich Martins, Luana Paganotto Leandro, Mauro Eugênio Medina Nunes, Thais Posser, Jeferson Franco
Glutamate is one of the predominant excitatory neurotransmitters released from the central nervous system; however, at high concentrations, this substance may induce excitotoxicity. This phenomenon...
{"title":"Investigating the impact of Psidium guajava leaf hydroalcoholic extract in improving glutamatergic toxicity-induced oxidative stress in Danio rerio larvae","authors":"Andressa Rubim Lopes, Dennis Guilherme Costa Silva, Nathane Rosa Rodrigues, Illana Kemmerich Martins, Luana Paganotto Leandro, Mauro Eugênio Medina Nunes, Thais Posser, Jeferson Franco","doi":"10.1080/15287394.2024.2337366","DOIUrl":"https://doi.org/10.1080/15287394.2024.2337366","url":null,"abstract":"Glutamate is one of the predominant excitatory neurotransmitters released from the central nervous system; however, at high concentrations, this substance may induce excitotoxicity. This phenomenon...","PeriodicalId":17418,"journal":{"name":"Journal of Toxicology and Environmental Health, Part A","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140568550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-18DOI: 10.1080/15287394.2023.2292709
Wan Shen, Hao Chen, Chiahao Shih, James Samet, Haiyan Tong
Exposure to ambient fine particulate matter (PM2.5) was found to produce vascular injury, possibly by activating platelets within days after exposure. The aim of this study was to investigate the m...
{"title":"Modulatory effects of dietary saturated fatty acids on platelet mitochondrial function following short-term exposure to ambient Particulate Matter (PM2.5)","authors":"Wan Shen, Hao Chen, Chiahao Shih, James Samet, Haiyan Tong","doi":"10.1080/15287394.2023.2292709","DOIUrl":"https://doi.org/10.1080/15287394.2023.2292709","url":null,"abstract":"Exposure to ambient fine particulate matter (PM2.5) was found to produce vascular injury, possibly by activating platelets within days after exposure. The aim of this study was to investigate the m...","PeriodicalId":17418,"journal":{"name":"Journal of Toxicology and Environmental Health, Part A","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138821037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-14DOI: 10.1080/15287394.2023.2293218
Andressa Yuri Fujiike, Larissa Cristina Bastos de Oliveira, Diego Luis Ribeiro, Érica Romão Pereira, Nádia Calvo Martins Okuyama, Anna Gabriele Prado dos Santos, Ilce Mara de Syllos Cólus, Juliana Mara Serpeloni
Docetaxel (DTX) is one of the chemotherapeutic drugs indicated as a first-line treatment against metastatic prostate cancer (mPCa). This study aimed to compare the impact of DTX on mPCa (DU-145) tu...
{"title":"Effects of docetaxel on metastatic prostate (DU-145) carcinoma cells cultured as 2D monolayers and 3D multicellular tumor spheroids","authors":"Andressa Yuri Fujiike, Larissa Cristina Bastos de Oliveira, Diego Luis Ribeiro, Érica Romão Pereira, Nádia Calvo Martins Okuyama, Anna Gabriele Prado dos Santos, Ilce Mara de Syllos Cólus, Juliana Mara Serpeloni","doi":"10.1080/15287394.2023.2293218","DOIUrl":"https://doi.org/10.1080/15287394.2023.2293218","url":null,"abstract":"Docetaxel (DTX) is one of the chemotherapeutic drugs indicated as a first-line treatment against metastatic prostate cancer (mPCa). This study aimed to compare the impact of DTX on mPCa (DU-145) tu...","PeriodicalId":17418,"journal":{"name":"Journal of Toxicology and Environmental Health, Part A","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138682930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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