{"title":"Effects of Vigabatrin on Patients with Epileptic Spasms and Focal Seizures","authors":"Y. Hirata, S. Hamano, S. Ikemoto, K. Kikuchi, R. Koichihara, Ryuki Matsuura, A. Daida, Hazuki Nonoyama","doi":"10.3805/JJES.38.139","DOIUrl":"https://doi.org/10.3805/JJES.38.139","url":null,"abstract":"スパズムと他の焦点性発作を同時期に有する症例におけるVigabatrin（VGB）の有効性を検討した。当センターでスパズムに対しVGBを投与した症例のうち結節性硬化症を除き、同時期に焦点性発作を有した11例を対象とした。後方視的に各発作型へのVGBの有効性、VGB中止による発作変化、最終診察時の発作転帰について評価した。経過観察は1年～6年9カ月でVGB継続期間は2週間～1年3カ月、全例で焦点性発作がスパズムに先行発症した。VGBの発作型別の有効性は、スパズムは消失例がなく、焦点性発作は消失の5例を含め半減以上が9例だった。10例でVGBを中止し、VGB投与中焦点性発作が半減以上だった8例全例で再発又は増加した。発作転帰は、両発作型消失と焦点性発作のみ消失が各々1例、スパズムのみ消失が2例、両発作型残存が7例だった。両発作型を同時期に有する症例において、VGBはスパズムには無効でも焦点性発作に有効性を認めた。VGBは、スパズムと共に焦点性発作への有効性も考慮し、VGB継続ならびに再開を検討すべきである。また、難治性てんかんにおけるスパズム以外の発作型に対するVGBの適応拡大が望まれる。","PeriodicalId":17426,"journal":{"name":"Journal of The Japan Epilepsy Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46635156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Patient with Temporal Lobe Epilepsy and Language Disorder Benefited from Rehabilitation Involving Divergent Thinking Tasks, Promoting Internal Motivation and Errorless Learning","authors":"Mayumi Hirozane, Satsuki Watanabe, Masako Watanabe","doi":"10.3805/JJES.38.147","DOIUrl":"https://doi.org/10.3805/JJES.38.147","url":null,"abstract":"","PeriodicalId":17426,"journal":{"name":"Journal of The Japan Epilepsy Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44606505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"てんかんと性ホルモン","authors":"Y. Murata, Masako Watanabe","doi":"10.3805/jjes.38.170","DOIUrl":"https://doi.org/10.3805/jjes.38.170","url":null,"abstract":"","PeriodicalId":17426,"journal":{"name":"Journal of The Japan Epilepsy Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43941612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"てんかん患者の小児期から成人期医療へのトランジッション―小児科医の所感―","authors":"","doi":"10.3805/jjes.38.137","DOIUrl":"https://doi.org/10.3805/jjes.38.137","url":null,"abstract":"","PeriodicalId":17426,"journal":{"name":"Journal of The Japan Epilepsy Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47104244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Critical Review on the ILAE Classification of the Epilepsies, 2017 -A Viewpoint of the Clinical Electroencephalography-","authors":"S. Ichijoh","doi":"10.3805/JJES.38.155","DOIUrl":"https://doi.org/10.3805/JJES.38.155","url":null,"abstract":"","PeriodicalId":17426,"journal":{"name":"Journal of The Japan Epilepsy Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44621821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multi-Spectrum Intrinsic Brain Activity for Motor Cortical Mapping as an Alternative to Electrical Cortical Stimulation","authors":"S. Neshige","doi":"10.3805/jjes.38.73","DOIUrl":"https://doi.org/10.3805/jjes.38.73","url":null,"abstract":"","PeriodicalId":17426,"journal":{"name":"Journal of The Japan Epilepsy Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44726696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Ono, A. Ishiyama, K. Sugai, E. Takeshita, Y. Shimizu-Motohashi, Takashi Saito, E. Nakagawa, M. Sasaki
{"title":"The Ictal EEG Findings of Non-convulsive Seizures in Ring Chromosome 20 Syndrome","authors":"H. Ono, A. Ishiyama, K. Sugai, E. Takeshita, Y. Shimizu-Motohashi, Takashi Saito, E. Nakagawa, M. Sasaki","doi":"10.3805/jjes.38.19","DOIUrl":"https://doi.org/10.3805/jjes.38.19","url":null,"abstract":"","PeriodicalId":17426,"journal":{"name":"Journal of The Japan Epilepsy Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48963675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Ikemoto, S. Hamano, R. Koichihara, A. Daida, Hazuki Nonoyama, Erika Hiwatari, Y. Hirata, Ryuki Matsuura, Tomoka Kambe
{"title":"Vigabatrin Treatment: A Single-Center Experience and Comparison with Adrenocorticotropic Hormone Therapy","authors":"S. Ikemoto, S. Hamano, R. Koichihara, A. Daida, Hazuki Nonoyama, Erika Hiwatari, Y. Hirata, Ryuki Matsuura, Tomoka Kambe","doi":"10.3805/jjes.38.3","DOIUrl":"https://doi.org/10.3805/jjes.38.3","url":null,"abstract":"","PeriodicalId":17426,"journal":{"name":"Journal of The Japan Epilepsy Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42923032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pathophysiological Analysis and Therapeutic Intervention of Dentatorubural-Pallidoluysian Atrophy (DRPLA) Transgenic Model Mice","authors":"T. Toyota","doi":"10.3805/jjes.38.61","DOIUrl":"https://doi.org/10.3805/jjes.38.61","url":null,"abstract":"","PeriodicalId":17426,"journal":{"name":"Journal of The Japan Epilepsy Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46466418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Oyazato, Tomoshi Nakajiri, Atsuko Kanagawa, S. Okita
{"title":"Effects of Topiramate for Nonconvulsive Status Epilepticus in Two Cases of Angelman Syndrome","authors":"Y. Oyazato, Tomoshi Nakajiri, Atsuko Kanagawa, S. Okita","doi":"10.3805/jjes.38.28","DOIUrl":"https://doi.org/10.3805/jjes.38.28","url":null,"abstract":"","PeriodicalId":17426,"journal":{"name":"Journal of The Japan Epilepsy Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47658184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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