This report aimed to reveal the characteristics of calcifying panniculitis in two cats. Two biopsies taken from the lumbosacral region of an 8-month old and a 1-year old, male, mixed breed cats were evaluated. Macroscopically, there were masses of different sizes varying from 1.5 to 2.5 cm in diameter. The masses had a generally firmness and were grayish-white in colour. Histopathology revealed necrotic and degenerative lipocytes in lobules of subcutaenous fat tissue. In some areas, there were lymphocyte, macrophage and neutrophil leukocytes infiltrations and connective tissue proliferation. There were also large calcifying areas at the centre of degenerated-necrotic fat lobules. Alizarin Red S detected the calcifying areas and Masson’s trichrome differentiated connective tissue proliferation. In ABC-P, CD3 slightly reacted with lymphocytes and lymphoblasts. Vimentin moderately reacted with connective tissue proliferation at the periphery of the necrotic areas and the septum. A1AC reacted in the cytoplasm of macrophages and peripheral necrotic areas. No reaction was determined with A1AT. In conclusion, such cases have not been documented in veterinary pathology. It is believed that the two cats possibly had a renal deficiency problem or nephrotic syndrome in the pathogenetic mechanism. It was also considered that A1AC (serine proteinase inhibitor) expressions could have a role in such cases despite there being no A1AT (another serine proteinase inhibitor) expression.
{"title":"Pathomorphological and Immunohistochemical Findings of Subacute Lobullary Calcifying Panniculitis in Two Cats","authors":"M. E. Alçığır, T. Kutlu, G. Alçıgır","doi":"10.9775/KVFD.2017.18745","DOIUrl":"https://doi.org/10.9775/KVFD.2017.18745","url":null,"abstract":"This report aimed to reveal the characteristics of calcifying panniculitis in two cats. Two biopsies taken from the lumbosacral region of an 8-month old and a 1-year old, male, mixed breed cats were evaluated. Macroscopically, there were masses of different sizes varying from 1.5 to 2.5 cm in diameter. The masses had a generally firmness and were grayish-white in colour. Histopathology revealed necrotic and degenerative lipocytes in lobules of subcutaenous fat tissue. In some areas, there were lymphocyte, macrophage and neutrophil leukocytes infiltrations and connective tissue proliferation. There were also large calcifying areas at the centre of degenerated-necrotic fat lobules. Alizarin Red S detected the calcifying areas and Masson’s trichrome differentiated connective tissue proliferation. In ABC-P, CD3 slightly reacted with lymphocytes and lymphoblasts. Vimentin moderately reacted with connective tissue proliferation at the periphery of the necrotic areas and the septum. A1AC reacted in the cytoplasm of macrophages and peripheral necrotic areas. No reaction was determined with A1AT. In conclusion, such cases have not been documented in veterinary pathology. It is believed that the two cats possibly had a renal deficiency problem or nephrotic syndrome in the pathogenetic mechanism. It was also considered that A1AC (serine proteinase inhibitor) expressions could have a role in such cases despite there being no A1AT (another serine proteinase inhibitor) expression.","PeriodicalId":17814,"journal":{"name":"Kafkas Universitesi Veteriner Fakultesi Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71269576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Romaz Mohammed Ahmed Omer, Mai Abdul Rahman Mohammed Masri, K. I. Jawasreh, Ikhlas Ahmed Nour, Ahmed Dayain Abdalla Biraima, Lutfi Mohamed-Ahmed Musa, Mohamed-Khair Aِbdalla Ahmed
{"title":"Yerli Sudan Baggara Sığırında Büyüme Hormonu ve İnsülin Benzeri Büyüme Faktörü 1 Genlerinin Seçili Genetik Polimorfizmlerinin Moleküler Tespiti","authors":"Romaz Mohammed Ahmed Omer, Mai Abdul Rahman Mohammed Masri, K. I. Jawasreh, Ikhlas Ahmed Nour, Ahmed Dayain Abdalla Biraima, Lutfi Mohamed-Ahmed Musa, Mohamed-Khair Aِbdalla Ahmed","doi":"10.9775/KVFD.2017.18556","DOIUrl":"https://doi.org/10.9775/KVFD.2017.18556","url":null,"abstract":"","PeriodicalId":17814,"journal":{"name":"Kafkas Universitesi Veteriner Fakultesi Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71270012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Bozukluhan, O. Merhan, H. I. Gokce, M. Öğün, Emine Atakişi, Şemiştan Kiziltepe, G. Gökçe
{"title":"Poksvirüs İle Doğal Enfekte Koyunlarda, Bazı Akut Faz Proteinler, Biyokimyasal Parametreler ve Oksidatif Stresin Belirlenmesi","authors":"K. Bozukluhan, O. Merhan, H. I. Gokce, M. Öğün, Emine Atakişi, Şemiştan Kiziltepe, G. Gökçe","doi":"10.9775/KVFD.2017.19167","DOIUrl":"https://doi.org/10.9775/KVFD.2017.19167","url":null,"abstract":"","PeriodicalId":17814,"journal":{"name":"Kafkas Universitesi Veteriner Fakultesi Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71270249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gencay Taşkın Taşçi, Zati Vatansever, N. Aydin, N. Ölmez, Atila Akça, M. Ö. Arslan, Neriman Mor, Barış Sarı
{"title":"Türkiye’nin Kuzeydoğu Anadolu Bölgesinde Kazlarda (Anser anser domesticus) Trypanosoma spp. Prevalansı ve Moleküler Karakterizasyonu","authors":"Gencay Taşkın Taşçi, Zati Vatansever, N. Aydin, N. Ölmez, Atila Akça, M. Ö. Arslan, Neriman Mor, Barış Sarı","doi":"10.9775/kvfd.2018.19488","DOIUrl":"https://doi.org/10.9775/kvfd.2018.19488","url":null,"abstract":"","PeriodicalId":17814,"journal":{"name":"Kafkas Universitesi Veteriner Fakultesi Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71270422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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