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Increased Prevalence of Ossification of Posterior Longitudinal Ligament and Increased Bone Mineral Density in Patients with Ossification of Nuchal Ligament 颈韧带骨化患者后纵韧带骨化率增高,骨密度增高
Pub Date : 2016-09-01 DOI: 10.14245/kjs.2016.13.3.139
Ki-Wan Kim, Y. Oh, Jong-pil Eun
Objective There are also few studies demonstrating the relationship between ossification of nuchal ligament (ONL) and ossification of posterior longitudinal ligament (OPLL). We compared the prevalence, location, and type of OPLL between patients with ONL and matched patients without ONL.We also compared the bone mineral densities (BMDs) between the 2 groups. Methods total of 124 cervical ONL patients were enrolled in this study. The control group of 124 patients was matched with 124 patients with ONL by age and sex on a 1:1 basis to minimize confounding factors. We reviewed the prevalence, location, and type of OPLL in both groups. Results The prevalence of OPLL was almost 2.5 times greater in patients with ONL than those without ONL. The mean value of BMD in patients with ONL was greater at the lumbar spine (L1-L4) than in patients without ONL. The mean T score of the lumbar spine was 0.25±1.68 in the patients with ONL and -0.73±1.64 in the patients without ONL. Conclusion The prevalence of OPLL in patients with ONL was significantly higher than in patients without ONL. Because ONL is innocuous and may be seen more readily than OPLL on simple cervical radiographs, clinicians should consider the possibility of coexisting OPLL when ONL, especially extensive ONL, is detected in patients with neck pain, radiculopathy, or myelopathy, to facilitate proper treatment.
目的对颈韧带骨化(ONL)与后纵韧带骨化(OPLL)之间的关系研究较少。我们比较了有ONL的患者和无ONL的匹配患者之间OPLL的患病率、位置和类型。比较两组患者的骨矿物质密度(BMDs)。方法选取124例颈部ONL患者作为研究对象。对照组124例患者与124例ONL患者按年龄和性别按1:1的比例配对,以尽量减少混杂因素。我们回顾了两组OPLL的患病率、位置和类型。结果有ONL患者的OPLL患病率几乎是无ONL患者的2.5倍。有ONL的患者在腰椎(L1-L4)的BMD平均值大于无ONL的患者。有ONL患者腰椎T评分平均值为0.25±1.68,无ONL患者腰椎T评分平均值为-0.73±1.64。结论有ONL患者的OPLL患病率明显高于无ONL患者。由于ONL是无害的,在简单的颈椎x线片上可能比OPLL更容易被发现,因此当在颈部疼痛、神经根病或脊髓病患者中检测到ONL,特别是广泛性ONL时,临床医生应考虑并发OPLL的可能性,以促进适当的治疗。
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引用次数: 8
Infectious Spondylodiscitis by Uncommon Pathogens: A Pitfall of Empirical Antibiotics 由罕见病原体引起的传染性脊柱炎:经验抗生素的陷阱
Pub Date : 2016-09-01 DOI: 10.14245/kjs.2016.13.3.97
S. Yu, D. H. Kim, H. Kim, K. Nam, B. Choi, I. Han
Objective The goal of this study is to evaluate the prevalence of spondylodiscitis (SD) caused by uncommon pathogens and review the efficacy of the treatment strategy including the coverage by usual empirical broad-spectrum antibiotic therapy. Methods Ninety-nine consecutive patients diagnosed and treated for infectious SD between January 2007 to May 2015 were reviewed retrospectively. The prevalence of uncommon SD, predisposing factors, antibiotics sensitivity, and clinical outcome were analyzed in comparison with that of common SD. Results Among 99 patients, 68 patients were culture positive. Out of 68 patients with positive culture results, 54 of them(79.4%) were common pathogen and 14 (20.6%) were uncommon pathogen. Postoperative SDs were significantly prevalent in uncommon SD(42.9%) than common SD(27.8%). Recurrence rate was higher in uncommon pathogen SD(14.3%) than common SD group (2.3%), and it showed statistically significant difference (p=0.025). Empirical antibiotics of vancomycin and 3rd or 4th generation cephalosporin covered 100% of nontuberculous common SD and 14.3% of uncommon SD. Conclusion In our study, the prevalence of uncommon SD was relatively high uncommon (20.5% of culture positive SD and 14.1% of total cases) and the coverage rate of empirical antibiotics for them were only 14.3%. In particular, the possibility of SD with fun gal, polymicrobial, or multiple drug resistant organism should be considered in SD unresponsive to broad spectrum antibiotics therapy.
目的评估由罕见病原体引起的脊椎炎(SD)的患病率,并回顾治疗策略的疗效,包括常规经验性广谱抗生素治疗的覆盖率。方法回顾性分析2007年1月至2015年5月诊治的99例感染性SD患者的临床资料。分析不常见SD与常见SD的患病率、易感因素、抗生素敏感性及临床转归。结果99例患者中培养阳性68例。68例培养阳性患者中,常见病原菌54例(79.4%),不常见病原菌14例(20.6%)。术后SD在不常见SD中的发生率(42.9%)明显高于常见SD(27.8%)。罕见致病菌SD组复发率(14.3%)高于常见致病菌SD组(2.3%),差异有统计学意义(p=0.025)。万古霉素和第三代或第四代头孢菌素的经验抗生素占非结核性常见SD的100%,占不常见SD的14.3%。结论本研究中,不常见SD患病率较高,占培养阳性SD的20.5%,占总病例的14.1%,经验抗生素覆盖率仅为14.3%。特别是,在SD对广谱抗生素治疗无反应时,应考虑SD与有趣的gal,多微生物或多重耐药菌的可能性。
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引用次数: 5
Balloon Kyphoplasty: An Effective Treatment for Kummell Disease? 球囊后凸成形术:Kummell病的有效治疗方法?
Pub Date : 2016-09-01 DOI: 10.14245/kjs.2016.13.3.102
Pius Kim, S. Kim
Objective The purpose of this study was to evaluate the efficacy of balloon kyphoplasty for treating Kummel disease accompanying severe osteoporosis. Methods Twelve patients with single-level Kummell disease accompanied by severe osteoporosis were enrolled in this investigation. After postural reduction for 1 or 2 days, balloon kyphoplasty was performed on the collapsed vertebrae. Clinical results, radiological parameters, and related complications were assessed at 7 days, 1 month and 6 months after the procedure. Results Prior to kyphoplasty, the mean pain score (according to the visual analogue scale) was 8.0. Seven days after the procedure, this score improved to 2.5. Despite the significant improvement compared to preoperative value, the score increased to 4.0 at 6 months after the procedure. The mean preoperative vertebral height loss was 55.4%. Kyphoplasty reduced this loss to 31.6%, but it increased to 38.7% at 6 months after the procedure. The kyphotic angle improved significantly from 22.4°±4.9° (before the procedure) to 10.1°±3.8° after surgery, However, the improved angle was not maintained 6 months after the procedure. The mean correction loss for the kyphotic deformity was 7.2° at 6 months after the procedure. Three out of 12 patients sustained adjacent fractures after balloon kyphoplasty within 6 months. Conclusion Although balloon kyphoplasty for treating Kummell disease is known to provide stabilization and pain relief, it may be associated with the development of adjacent fractures and aggravated kyphosis.
目的评价球囊后凸成形术治疗Kummel病合并严重骨质疏松症的疗效。方法选取12例伴有严重骨质疏松症的单级Kummell病患者作为研究对象。体位复位1或2天后,对塌陷的椎体进行球囊后凸成形术。分别于术后7天、1个月和6个月评估临床结果、影像学参数和相关并发症。结果后凸成形术前,平均疼痛评分(按视觉模拟评分)为8.0。手术后7天,该分数提高到2.5分。尽管与术前相比有显著改善,但在手术后6个月评分上升至4.0。平均术前椎体高度损失为55.4%。后凸成形术将这一损失减少到31.6%,但在手术后6个月增加到38.7%。后凸角从术前的22.4°±4.9°明显改善到术后的10.1°±3.8°,但术后6个月后未保持改善的角度。术后6个月后凸畸形的平均矫正损失为7.2°。12例患者中有3例术后6个月内发生相邻骨折。结论虽然已知球囊后凸成形术治疗Kummell病可提供稳定和疼痛缓解,但它可能与邻近骨折的发展和后凸加重有关。
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引用次数: 19
The Safety and Decision Making of Instrumented Surgery in Infectious Spondylitis 感染性脊柱炎器械手术的安全性与决策
Pub Date : 2016-09-01 DOI: 10.14245/kjs.2016.13.3.120
K. Baek, Young-Seok Lee, D. Kang, C. Lee, S. Hwang, I. Park
Objective Infectious spondylitis is mostly managed by appropriate antibiotic treatment options, and some patients may require surgical interventions. However, surgical interventions that use spinal instrumentation to correct the mechanical instability may be associated with the risk of an increase in the recurrence rate. In this study, we investigated whether spinal instrumentation effects on recurrence of infectious spondylitis. Methods The study was conducted as a retrospective study by dividing the subjects into the noninstrumentation surgery and instrumentation surgery groups among a total of 95 patients who had received surgical interventions in infectious spondylitis from 2009 to 2014. The study investigated patient variables such as underlying illness, presumed source of infection, clinical data, laboratory and radiological data, and ultimate outcome, and compared them between the 2 groups. Results In the 95 patients, instrumentation was not used in 21 patients but it was used in 74 patients. When the disease involved ≥3 vertebral bodies, lumbosacral level and epidural part, noninstrumentation surgery was mainly conducted, but when the disease involved the thoracic level and psoas muscle part, instrumentation surgery was mainly conducted. However, there were no differences between the 2 groups in terms of the recurrence rate and the incidence of primary failure. Conclusion The use of instrumentation in treating infectious spondylitis was determined by the level of involvement and part of the infection, but the use of instrumentation did not cause any increases in the recurrence rate and the incidence of primary failure.
目的传染性脊柱炎大多通过适当的抗生素治疗,部分患者可能需要手术干预。然而,使用脊柱内固定来纠正机械不稳定的手术干预可能与复发率增加的风险相关。在这项研究中,我们研究了脊柱内固定是否会影响感染性脊柱炎的复发。方法采用回顾性研究的方法,将2009 - 2014年接受感染性脊柱炎手术干预的95例患者分为非器械固定组和器械固定组。该研究调查了患者的变量,如潜在疾病、假定的感染源、临床数据、实验室和放射学数据以及最终结果,并在两组之间进行了比较。结果95例患者中21例未使用器械,74例使用器械。当病变累及≥3个椎体、腰骶段及硬膜外部分时,以非固定化手术为主,累及胸段及腰肌部分时,以固定化手术为主。然而,两组在复发率和原发失败发生率方面没有差异。结论使用器械治疗感染性脊柱炎取决于受累程度和感染部位,但器械的使用并未导致复发率和原发性失败率的增加。
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引用次数: 9
The Surgical Overcorrection of Lenke Type 1 Deformities with Selective Fusion Segments: What Happens to the Coronal Balance? 选择性融合节段矫治Lenke 1型畸形:冠状平衡发生了什么?
Pub Date : 2016-09-01 DOI: 10.14245/kjs.2016.13.3.151
Y. Atici, S. Erdoğan, Y. Akman, M. Mert, Engin Çarkçı, T. Tuzuner
Purpose The aim of our study is to determine the alterations on coronal balance after overcorrection of Lenke type 1 curve, retrospectively. Methods Datas of 34 patients (29 female, 5 male patients; mean age, 16.3±3.3 years; range, 13-24 years) surgically treated for scoliosis between 2004 and 2010 were reviewed, retrospectively. The adolescent idiopathic scoliosis patients with Lenke type 1 curve treated with only posterior pedicle screw and postoperative thoracic curves less than 10° by Cobb method on frontal plane were enrolled in this study. Mean follow-up period was 52.5±29.7 months. Results The mean amount of the preoperative thoracic curves was measured as 41.2°±6.1° (range, 30°-56°). The mean amount of the early postoperative thoracic curves was measured as 6.5°±1.8° (range, 3°-9°). The mean amount of the thoracic curves was measured as 8.5°±4.6° (range, 3°-22°) during the last follow-up (p=0.01). The mean preoperative coronal balance was measured as 8.5mm(range, 1-30mm). The mean early postoperative coronal balance was measured as 3.5mm(range, 0-36 mm). The mean coronal balance was measured as 5.5mm(range, 0-38mm) during the last follow-up (p>0.05). Conclusion We suggest that Lenke type 1B and 1C should be carefully evaluated and the fusion levels should be accurately selected in order to maintain the correction of coronal balance. We suggest that selective fusion with overcorrection in Lenke type 1A are applied to curves that can be corrected lumbar curve at the preoperative bending radiograph and curves that not have coronal decompensation and >10° distal junctional kyphosis, preoperatively.
目的回顾性研究Lenke 1型曲线过校正后冠状平衡的变化。方法34例患者资料(女性29例,男性5例;平均年龄16.3±3.3岁;回顾性回顾了2004年至2010年间13-24岁的脊柱侧凸手术治疗病例。本研究纳入仅后路椎弓根螺钉治疗Lenke 1型弯曲的青少年特发性脊柱侧凸患者,术后胸前平面Cobb法弯曲小于10°。平均随访时间52.5±29.7个月。结果术前胸曲度平均为41.2°±6.1°(范围30°-56°)。术后早期胸椎弯曲平均为6.5°±1.8°(范围3°-9°)。最后一次随访时,平均胸椎弯曲量为8.5°±4.6°(范围3°-22°)(p=0.01)。术前冠状平衡平均值为8.5mm(范围1-30mm)。术后早期冠状平衡平均值为3.5mm(范围0-36 mm)。末次随访时冠状平衡平均值为5.5mm(范围0 ~ 38mm),差异有统计学意义(p>0.05)。结论我们建议仔细评估Lenke 1B型和1C型,准确选择融合水平,以维持冠状平衡的矫正。我们建议Lenke 1A型的选择性融合过度矫正适用于术前弯曲x线片上可以矫正的腰椎弯曲,以及术前没有冠状失代偿和>10°远端关节后凸的弯曲。
{"title":"The Surgical Overcorrection of Lenke Type 1 Deformities with Selective Fusion Segments: What Happens to the Coronal Balance?","authors":"Y. Atici, S. Erdoğan, Y. Akman, M. Mert, Engin Çarkçı, T. Tuzuner","doi":"10.14245/kjs.2016.13.3.151","DOIUrl":"https://doi.org/10.14245/kjs.2016.13.3.151","url":null,"abstract":"Purpose The aim of our study is to determine the alterations on coronal balance after overcorrection of Lenke type 1 curve, retrospectively. Methods Datas of 34 patients (29 female, 5 male patients; mean age, 16.3±3.3 years; range, 13-24 years) surgically treated for scoliosis between 2004 and 2010 were reviewed, retrospectively. The adolescent idiopathic scoliosis patients with Lenke type 1 curve treated with only posterior pedicle screw and postoperative thoracic curves less than 10° by Cobb method on frontal plane were enrolled in this study. Mean follow-up period was 52.5±29.7 months. Results The mean amount of the preoperative thoracic curves was measured as 41.2°±6.1° (range, 30°-56°). The mean amount of the early postoperative thoracic curves was measured as 6.5°±1.8° (range, 3°-9°). The mean amount of the thoracic curves was measured as 8.5°±4.6° (range, 3°-22°) during the last follow-up (p=0.01). The mean preoperative coronal balance was measured as 8.5mm(range, 1-30mm). The mean early postoperative coronal balance was measured as 3.5mm(range, 0-36 mm). The mean coronal balance was measured as 5.5mm(range, 0-38mm) during the last follow-up (p>0.05). Conclusion We suggest that Lenke type 1B and 1C should be carefully evaluated and the fusion levels should be accurately selected in order to maintain the correction of coronal balance. We suggest that selective fusion with overcorrection in Lenke type 1A are applied to curves that can be corrected lumbar curve at the preoperative bending radiograph and curves that not have coronal decompensation and >10° distal junctional kyphosis, preoperatively.","PeriodicalId":17867,"journal":{"name":"Korean Journal of Spine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90348724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Comparison of Radiologic Outcomes of Different Methods in Single-Level Anterior Cervical Discectomy and Fusion 单节段颈椎前路椎间盘切除术与融合术不同方法的放射学效果比较
Pub Date : 2016-09-01 DOI: 10.14245/kjs.2016.13.3.91
O. Kwon, D. Son, Sang Weon Lee, G. Song
Objective Anterior cervical discectomy and fusion (ACDF) is a choice of surgical procedure for cervical degenerative diseases associated with radiculopathy or myelopathy. However, the patients undergoing ACDF still have problems. The purpose of the present study is to evaluate the radiologic results of 3 different methods in single-level ACDF. Methods We conducted a retrospective collection of radiological data from January 2011 to December 2014. A total of 67 patients were included in this study. The patients were divided into 3 groups by operation procedure: using stand-alone cage (group cage, n=20); polyether-ether-ketone (PEEK)-titanium combined anchored cage (group AC, n=21); and anterior cervical cage-plate (group CP, n=26). Global cervical lordosis (C2-C7 Cobb angle), fused segment height, fusion rate, and cervical range of motion (ROM) were measured and analyzed at serial preoperative, postoperative, 6-month, and final 1-year follow-up. Results Successful bone fusion was achieved in all patients at the final follow-up examination; however, the loss of disc height over 3 mm at the surgical level was observed in 6 patients in group cage. Groups AC and CP yielded significantly better outcomes than group cage in fused segment height and cervical ROM(p=0.01 and p=0.02, respectively). Furthermore, group AC had similar radiologic outcomes to those of group CP. Conclusion The PEEK-titanium combined anchored cage may be a good alternative procedure in terms of reducing complications induced by plate after ACDF.
目的颈椎前路椎间盘切除术融合术(ACDF)是治疗伴有神经根病或脊髓病的颈椎退行性疾病的首选手术方法。然而,接受ACDF的患者仍然存在问题。本研究的目的是评价3种不同方法在单节段ACDF中的放射学结果。方法回顾性收集2011年1月至2014年12月的放射学资料。本研究共纳入67例患者。按手术方式将患者分为3组:采用单机笼(组笼,n=20);聚醚-醚-酮(PEEK)-钛复合锚固笼(AC组,n=21);颈椎前路固定钢板(CP组,n=26)。在术前、术后、6个月和最后1年的连续随访中测量和分析颈椎前凸度(C2-C7 Cobb角)、融合节段高度、融合率和颈椎活动度(ROM)。结果所有患者术后随访均成功完成骨融合;然而,在组笼中观察到6例患者在手术水平椎间盘高度损失超过3mm。在融合节段高度和颈椎ROM方面,AC组和CP组明显优于笼组(p=0.01和p=0.02)。此外,AC组与CP组放射学结果相似。结论peek -钛联合锚定笼可能是减少ACDF术后钢板并发症的良好替代方法。
{"title":"Comparison of Radiologic Outcomes of Different Methods in Single-Level Anterior Cervical Discectomy and Fusion","authors":"O. Kwon, D. Son, Sang Weon Lee, G. Song","doi":"10.14245/kjs.2016.13.3.91","DOIUrl":"https://doi.org/10.14245/kjs.2016.13.3.91","url":null,"abstract":"Objective Anterior cervical discectomy and fusion (ACDF) is a choice of surgical procedure for cervical degenerative diseases associated with radiculopathy or myelopathy. However, the patients undergoing ACDF still have problems. The purpose of the present study is to evaluate the radiologic results of 3 different methods in single-level ACDF. Methods We conducted a retrospective collection of radiological data from January 2011 to December 2014. A total of 67 patients were included in this study. The patients were divided into 3 groups by operation procedure: using stand-alone cage (group cage, n=20); polyether-ether-ketone (PEEK)-titanium combined anchored cage (group AC, n=21); and anterior cervical cage-plate (group CP, n=26). Global cervical lordosis (C2-C7 Cobb angle), fused segment height, fusion rate, and cervical range of motion (ROM) were measured and analyzed at serial preoperative, postoperative, 6-month, and final 1-year follow-up. Results Successful bone fusion was achieved in all patients at the final follow-up examination; however, the loss of disc height over 3 mm at the surgical level was observed in 6 patients in group cage. Groups AC and CP yielded significantly better outcomes than group cage in fused segment height and cervical ROM(p=0.01 and p=0.02, respectively). Furthermore, group AC had similar radiologic outcomes to those of group CP. Conclusion The PEEK-titanium combined anchored cage may be a good alternative procedure in terms of reducing complications induced by plate after ACDF.","PeriodicalId":17867,"journal":{"name":"Korean Journal of Spine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82733291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Pneumocephalus and Pneumorrhachis due to a Subarachnoid Pleural Fistula That Developed after Thoracic Spine Surgery 胸椎手术后发生的蛛网膜下腔胸膜瘘导致的脑气和气腹
Pub Date : 2016-09-01 DOI: 10.14245/kjs.2016.13.3.164
G. Lee, M. Lee, Woo-Jae Kim, Ho-Sang Kim, Jeong-Ho Kim, Yun-Suk Kim
Development of a communication between the spinal subarachnoid space and the pleural space after thoracic spine surgery is uncommon. Subarachnoid pleural fistula (SAPF), a distressing condition, involves cerebrospinal fluid leakage. Here we report an unusual case of SAPF, occurring after thoracic spine surgery, that was further complicated by pneumocephalus and pneumorrhachis postthoracentesis, which was performed for unilateral pleural effusion.
在胸椎手术后,脊髓蛛网膜下腔与胸膜腔之间的交流并不常见。蛛网膜下腔胸膜瘘(SAPF)是一种令人痛苦的疾病,涉及脑脊液漏。我们在此报告一个不寻常的SAPF病例,发生在胸椎手术后,并因单侧胸腔积液而在胸腔穿刺后进一步并发脑气和气出血。
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引用次数: 4
The Use of Gentamicin-Impregnated Collagen Sponge for Reducing Surgical Site Infection after Spine Surgery 庆大霉素浸渍胶原蛋白海绵在减少脊柱术后手术部位感染中的应用
Pub Date : 2016-09-01 DOI: 10.14245/kjs.2016.13.3.129
Jinsol Han, Se-Hoon Kim, Sung-Won Jin, Seung-Hwan Lee, Bum-Joon Kim, Sang-Dae Kim, D. Lim
Objective Surgical site infection (SSI) is the one of the most frequent complications in hospitalized patients, and it extends hospital stays and causes extra morbidities. To reduce SSI after spine surgery, we applied the gentamicin-impregnated collagen sponge (Collatamp G) during the operation and analyzed the results retrospectively. Methods Between October 2012 and December 2015, we collected data who applied the Collatamp G in spine surgery at a single institution. Demographic data of patients and another possible risk factors of SSI were also included, and we assessed the correlation between the risk factors and the developing of SSI by reviewing electronic medical records retrospectively. Results Three percent of all patients (10 of 280) developed the SSI and only 0.8% of patients who applied Collatamp G developed SSI (1 of 119). Otherwise, 5% of patients who did not apply Collatamp G developed SSI (9 of 161) (p=0.034). We also analyzed the correlation between SSI and other potential risk factors but nothings showed statistical correlation with SSI. Conclusion In this study, there were statistically significant results that SSI rate was decreased in the group of patients using Collatamp G in spine surgery generally. However, further studies are required to resolve some limitations in the future.
目的手术部位感染(SSI)是住院患者最常见的并发症之一,它延长了住院时间并引起了额外的发病率。为了减少脊柱术后SSI,我们在术中应用庆大霉素浸没的胶原海绵(Collatamp G),并对结果进行回顾性分析。方法2012年10月至2015年12月,我们收集了在单一机构脊柱外科应用Collatamp G的数据。我们还纳入了患者的人口统计数据和其他可能发生SSI的危险因素,并通过回顾电子病历来评估危险因素与SSI发生的相关性。结果280例患者中有10例(3%)发生了SSI,使用Collatamp G的患者中只有0.8%(119例中有1例)发生了SSI。另外,5%未使用Collatamp G的患者发生SSI(161例中有9例)(p=0.034)。我们还分析了SSI与其他潜在危险因素的相关性,但没有发现与SSI有统计学相关性。结论在本研究中,脊柱手术中使用Collatamp G的患者SSI发生率普遍降低,有统计学意义。然而,需要进一步的研究来解决未来的一些局限性。
{"title":"The Use of Gentamicin-Impregnated Collagen Sponge for Reducing Surgical Site Infection after Spine Surgery","authors":"Jinsol Han, Se-Hoon Kim, Sung-Won Jin, Seung-Hwan Lee, Bum-Joon Kim, Sang-Dae Kim, D. Lim","doi":"10.14245/kjs.2016.13.3.129","DOIUrl":"https://doi.org/10.14245/kjs.2016.13.3.129","url":null,"abstract":"Objective Surgical site infection (SSI) is the one of the most frequent complications in hospitalized patients, and it extends hospital stays and causes extra morbidities. To reduce SSI after spine surgery, we applied the gentamicin-impregnated collagen sponge (Collatamp G) during the operation and analyzed the results retrospectively. Methods Between October 2012 and December 2015, we collected data who applied the Collatamp G in spine surgery at a single institution. Demographic data of patients and another possible risk factors of SSI were also included, and we assessed the correlation between the risk factors and the developing of SSI by reviewing electronic medical records retrospectively. Results Three percent of all patients (10 of 280) developed the SSI and only 0.8% of patients who applied Collatamp G developed SSI (1 of 119). Otherwise, 5% of patients who did not apply Collatamp G developed SSI (9 of 161) (p=0.034). We also analyzed the correlation between SSI and other potential risk factors but nothings showed statistical correlation with SSI. Conclusion In this study, there were statistically significant results that SSI rate was decreased in the group of patients using Collatamp G in spine surgery generally. However, further studies are required to resolve some limitations in the future.","PeriodicalId":17867,"journal":{"name":"Korean Journal of Spine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79059702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Surgical Outcomes of Anterior Cervical Fusion Using Deminaralized Bone Matrix as Stand-Alone Graft Material: Single Arm, Pilot Study 使用去矿化骨基质作为独立移植材料的颈椎前路融合术的手术效果:单臂,试点研究
Pub Date : 2016-09-01 DOI: 10.14245/kjs.2016.13.3.114
Ho-Jung Chung, J. Hur, K. Ryu, Jin-Sung Kim, Ji-hoon Seong
Objective To investigate the safety and efficacy of demineralized bone matrix (DBM) as a bone graft substitute for anterior cervical discectomy and fusion (ACDF) surgery. Methods Twenty consecutive patients treated with ACDF using stand-alone polyestheretherketone (PEEK) cages (Zero-P) with DBM(CGDBM100) were prospectively evaluated with a minimum of 6 months of follow-up. Radiologic efficacy was evaluated with a 6-point scoring method for osseous fusion using plain radiograph and computed tomogrpahy scans. Clinical efficacy was evaluated using the visual analogue scale (VAS), Owestry disability index (ODI), and short-form health questionnaire-36. The safety of the bone graft substitute was assessed with vital sign monitoring and a survey measuring complications at each follow-up visit. Results There were significant improvements in VAS and ODI scores at a mean 6-month follow-up. Six months after surgery, solid fusion was achieved in all patients. Mean score on the 6-point scoring system was 5.1, and bony formation was found to score at least 4 points in all patients. There was no case with implant-related complications such as cage failure or migration, and no complications associated with the use of CGDBM100. Conclusion ACDF using CGDBM100 demonstrated good clinical and radiologic outcomes. The fusion rate was comparable with the published results of traditional ACDF. Therefore, the results of this study suggest that the use of a PEEK cage packed with DBM for ACDF is a safe and effective alternative to the gold standard of autologous iliac bone graft.
目的探讨脱矿化骨基质(DBM)作为植骨替代物用于颈前路椎间盘切除术融合术(ACDF)的安全性和有效性。方法对连续20例使用独立聚醚醚酮(PEEK)笼(0 - p)加DBM(CGDBM100)治疗ACDF的患者进行前瞻性评估,随访至少6个月。x线平片和计算机断层扫描采用6点评分法评估骨融合的放射学疗效。采用视觉模拟量表(VAS)、Owestry残疾指数(ODI)和简易健康问卷-36评价临床疗效。在每次随访时,通过生命体征监测和并发症调查来评估骨移植替代物的安全性。结果平均随访6个月,VAS和ODI评分均有显著改善。术后6个月,所有患者均实现了固体融合。6分评分系统的平均评分为5.1分,所有患者的骨形成评分至少为4分。无种植体相关并发症,如保持器失效或移位,也无使用CGDBM100相关并发症。结论CGDBM100应用于ACDF具有良好的临床和放射效果。融合速率与已发表的传统ACDF结果相当。因此,本研究结果表明,使用填充DBM的PEEK笼进行ACDF是一种安全有效的替代自体髂骨移植金标准的方法。
{"title":"Surgical Outcomes of Anterior Cervical Fusion Using Deminaralized Bone Matrix as Stand-Alone Graft Material: Single Arm, Pilot Study","authors":"Ho-Jung Chung, J. Hur, K. Ryu, Jin-Sung Kim, Ji-hoon Seong","doi":"10.14245/kjs.2016.13.3.114","DOIUrl":"https://doi.org/10.14245/kjs.2016.13.3.114","url":null,"abstract":"Objective To investigate the safety and efficacy of demineralized bone matrix (DBM) as a bone graft substitute for anterior cervical discectomy and fusion (ACDF) surgery. Methods Twenty consecutive patients treated with ACDF using stand-alone polyestheretherketone (PEEK) cages (Zero-P) with DBM(CGDBM100) were prospectively evaluated with a minimum of 6 months of follow-up. Radiologic efficacy was evaluated with a 6-point scoring method for osseous fusion using plain radiograph and computed tomogrpahy scans. Clinical efficacy was evaluated using the visual analogue scale (VAS), Owestry disability index (ODI), and short-form health questionnaire-36. The safety of the bone graft substitute was assessed with vital sign monitoring and a survey measuring complications at each follow-up visit. Results There were significant improvements in VAS and ODI scores at a mean 6-month follow-up. Six months after surgery, solid fusion was achieved in all patients. Mean score on the 6-point scoring system was 5.1, and bony formation was found to score at least 4 points in all patients. There was no case with implant-related complications such as cage failure or migration, and no complications associated with the use of CGDBM100. Conclusion ACDF using CGDBM100 demonstrated good clinical and radiologic outcomes. The fusion rate was comparable with the published results of traditional ACDF. Therefore, the results of this study suggest that the use of a PEEK cage packed with DBM for ACDF is a safe and effective alternative to the gold standard of autologous iliac bone graft.","PeriodicalId":17867,"journal":{"name":"Korean Journal of Spine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75927555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Three-Years Outcome of Microdiscectomy via Paramedian Approach for Lumbar Foraminal or Extraforaminal Disc Herniations in Elderly Patients over 65 Years Old 65岁以上老年患者椎间孔或椎间孔外椎间盘突出的准中心入路显微椎间盘切除术3年疗效分析
Pub Date : 2016-09-01 DOI: 10.14245/kjs.2016.13.3.107
Ch Yeo, Ikchan Jeon, Sang Woo Kim, Sam Kyu Ko, Byung Kil Woo, Kwang Chul Song
Objective Lumbar foraminal or extraforaminal disc herniations (FEFDH) have unusual clinical features and higher incidence in elderly patients compared to usual intraspinal canal disc herniations. We evaluated the efficacy of microdiscectomy via paramedian approach for lumbar FEFDH in elderly patients over the age of 65. Methods Retrospective study was performed in 68 patients over the age of 65 (23 male and 45 female patients; 71.46±3.87 years) who underwent microdiscectomy via paramedian approach for unilateral lumbar FEFDH causing sciatica. The radiological factors including degree of slippage, presence of instability, disc height, and degree of disc degeneration; pain and functional status by the means of visual analogue scale score, Oswestry Disability Index score, and Macnab classification were analyzed preoperatively and during the postoperative follow-up period of 3 years to evaluate the efficacy of the surgical treatment. Results Pain and functional status improved according to short- and long-term follow-up evaluations after surgery. Radiological changes following surgery, which can be understood as structural deteriorations and deformations, did not represent patient condition. Nine patients underwent additional surgery due to sustained or recurring leg pain of aggravation of back pain, and fusion surgery was required for 3 patients. Degree of preoperative slippage was the only statistically significant factor related to additional surgery (p<0.05). Conclusion Microdiscectomy via paramedian approach for FEFDH may be a good surgical alternative in elderly patients. Radiological changes after surgery did not show a concordance with patients' actual functional status. The excessive preoperative slippage tended to lead to unfavorable result after surgery and was associated with additional surgery.
目的腰椎椎间孔或椎间孔外椎间盘突出症(FEFDH)与普通的椎管内椎间盘突出症相比具有不同寻常的临床特点和较高的发病率。我们评估了65岁以上的老年患者通过准正中入路显微椎间盘切除术治疗腰椎FEFDH的疗效。方法对68例65岁以上患者(男23例,女45例;(71.46±3.87岁),单侧腰椎FEFDH引起坐骨神经痛,经旁正中入路行显微椎间盘切除术。放射学因素包括滑脱程度、不稳定性、椎间盘高度和椎间盘退变程度;术前及术后随访3年,采用视觉模拟量表评分、Oswestry残疾指数评分、Macnab分级等方法分析患者的疼痛和功能状态,评价手术治疗的效果。结果术后短期和长期随访评价疼痛和功能状态均有改善。手术后的影像学改变可以理解为结构恶化和变形,但不能代表患者的病情。9例患者因持续或复发性腿部疼痛或背部疼痛加重而接受了额外的手术,3例患者需要进行融合手术。术前滑脱程度是唯一与追加手术相关的有统计学意义的因素(p<0.05)。结论经旁院入路显微椎间盘切除术治疗老年FEFDH可能是一种较好的手术选择。手术后的影像学改变与患者的实际功能状态不一致。术前滑脱过多往往会导致术后不良的结果,并与追加手术有关。
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引用次数: 6
期刊
Korean Journal of Spine
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