Shin Mei Chan, Vitor F Martins, Kathleen Marsh, Kang Wang, Jake T Weeks, Aiguo Han, Meng Yin, Kathryn J Fowler, Claude B Sirlin, Cheng William Hong
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as nonalcoholic fatty liver disease, is the fastest-growing cause of chronic liver disease worldwide, affecting approximately 30% of the global population. Imaging is vital for detecting, quantifying, and monitoring hepatic steatosis-the defining abnormality of MASLD-and subsequent fibrosis-the key determinant of liver-related outcomes. This review summarizes the principles, clinical usage, efficacy, and advancements in various imaging modalities for the noninvasive assessment of hepatic steatosis and fibrosis, with an emphasis on ultrasound, CT, and MRI. Additionally, this review explores the evolving landscape of MASLD diagnostic approaches, including machine-learning techniques, opportunistic screening, standardized imaging guidelines, and therapies, emphasizing the pivotal role that radiologists can play in shaping these developments.
{"title":"Imaging Evaluation for Steatotic Liver Disease.","authors":"Shin Mei Chan, Vitor F Martins, Kathleen Marsh, Kang Wang, Jake T Weeks, Aiguo Han, Meng Yin, Kathryn J Fowler, Claude B Sirlin, Cheng William Hong","doi":"10.3348/kjr.2025.0966","DOIUrl":"https://doi.org/10.3348/kjr.2025.0966","url":null,"abstract":"<p><p>Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as nonalcoholic fatty liver disease, is the fastest-growing cause of chronic liver disease worldwide, affecting approximately 30% of the global population. Imaging is vital for detecting, quantifying, and monitoring hepatic steatosis-the defining abnormality of MASLD-and subsequent fibrosis-the key determinant of liver-related outcomes. This review summarizes the principles, clinical usage, efficacy, and advancements in various imaging modalities for the noninvasive assessment of hepatic steatosis and fibrosis, with an emphasis on ultrasound, CT, and MRI. Additionally, this review explores the evolving landscape of MASLD diagnostic approaches, including machine-learning techniques, opportunistic screening, standardized imaging guidelines, and therapies, emphasizing the pivotal role that radiologists can play in shaping these developments.</p>","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145912161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Access and Reimbursement for Artificial Intelligence in Radiology: A Central Asian Perspective.","authors":"Tairkhan Dautov, Ainara Darbaeva, Zhuldyz Aimagambetova, Vitaly Polushkin","doi":"10.3348/kjr.2025.1638","DOIUrl":"https://doi.org/10.3348/kjr.2025.1638","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145912085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Access and Reimbursement for Artificial Intelligence in Radiology: A Macau Perspective.","authors":"Chon Man Ieong, Mei Leng Ieong, Soi Chau Kong","doi":"10.3348/kjr.2025.1630","DOIUrl":"https://doi.org/10.3348/kjr.2025.1630","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145912123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evolving Role of Contrast-Enhanced Mammography-Guided Biopsy: Clinical Value and Limitations.","authors":"Chotai Niketa","doi":"10.3348/kjr.2025.1790","DOIUrl":"https://doi.org/10.3348/kjr.2025.1790","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145912110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comments on \"Pretreatment [⁶⁸Ga]-PSMA-11 PET/CT to Predict the Response to Treatment With Immune Checkpoint Inhibitors Plus Tyrosine Kinase Inhibitors in Patients With Metastatic Renal Cell Carcinoma\".","authors":"Dongdong Zhang, Junbin Zhang, Ming Cai","doi":"10.3348/kjr.2025.1732","DOIUrl":"https://doi.org/10.3348/kjr.2025.1732","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145912113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Woojin Yi, Hyo Jin Lee, Kyung Won Kim, Abdullah S Al-Yousef, Mitulkumar Patel, Saurabh Pallod, Katherine M Krajewski
{"title":"Network Radiology as a New Paradigm in Radiology Practice: Recent Insights From Integrated Health Systems in the United States.","authors":"Woojin Yi, Hyo Jin Lee, Kyung Won Kim, Abdullah S Al-Yousef, Mitulkumar Patel, Saurabh Pallod, Katherine M Krajewski","doi":"10.3348/kjr.2025.1690","DOIUrl":"https://doi.org/10.3348/kjr.2025.1690","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145912147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shao-Hao Chen, Xiao-Hui Wu, Qian-Ren-Shun Qiu, Shao-Ming Chen, Jie Zang, Jun-Ming Zhu, Cheng-Long Zeng, Wei-Bing Miao, Xue-Yi Xue, Ning Xu
{"title":"Response to Comments on \"Pretreatment [⁶⁸Ga]-PSMA-11 PET/CT to Predict the Response to Treatment With Immune Checkpoint Inhibitors Plus Tyrosine Kinase Inhibitors in Patients With Metastatic Renal Cell Carcinoma\".","authors":"Shao-Hao Chen, Xiao-Hui Wu, Qian-Ren-Shun Qiu, Shao-Ming Chen, Jie Zang, Jun-Ming Zhu, Cheng-Long Zeng, Wei-Bing Miao, Xue-Yi Xue, Ning Xu","doi":"10.3348/kjr.2025.1800","DOIUrl":"https://doi.org/10.3348/kjr.2025.1800","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145912157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The spleen is frequently referred to as the "silent and forgotten" organ of the abdomen by clinicians and radiologists, primarily because of the secondary nature of most splenic pathologies and their relative rarity compared with hepatic diseases. Nevertheless, the term splenomegaly frequently appears in radiological reports. Although it is often reported in the context of a known underlying cause, it is also commonly used as a purely descriptive term without reference to the underlying etiology. Although splenomegaly may occasionally be idiopathic, it commonly represents an underlying pathological condition. Therefore, radiologists are instrumental in accurately identifying splenomegaly, evaluating plausible differential diagnoses, and guiding appropriate clinical management and workups. Given the wide spectrum of etiologies and overlapping imaging features, a systematic approach is essential to enhance the diagnostic accuracy and clinical relevance. Here, we present a comprehensive literature review of splenomegaly from a radiological perspective, with causes categorized according to pathophysiological mechanisms.
{"title":"Radiological Approach to Splenomegaly: Etiologies, Pathophysiologies, and Diagnostic Strategies.","authors":"Na Yeon Han, Yong Park, Min Ju Kim","doi":"10.3348/kjr.2025.0848","DOIUrl":"https://doi.org/10.3348/kjr.2025.0848","url":null,"abstract":"<p><p>The spleen is frequently referred to as the \"silent and forgotten\" organ of the abdomen by clinicians and radiologists, primarily because of the secondary nature of most splenic pathologies and their relative rarity compared with hepatic diseases. Nevertheless, the term splenomegaly frequently appears in radiological reports. Although it is often reported in the context of a known underlying cause, it is also commonly used as a purely descriptive term without reference to the underlying etiology. Although splenomegaly may occasionally be idiopathic, it commonly represents an underlying pathological condition. Therefore, radiologists are instrumental in accurately identifying splenomegaly, evaluating plausible differential diagnoses, and guiding appropriate clinical management and workups. Given the wide spectrum of etiologies and overlapping imaging features, a systematic approach is essential to enhance the diagnostic accuracy and clinical relevance. Here, we present a comprehensive literature review of splenomegaly from a radiological perspective, with causes categorized according to pathophysiological mechanisms.</p>","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145912093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Access and Reimbursement for Artificial Intelligence in Radiology: A Japanese Perspective.","authors":"Kenji Hirata, Mototaka Miyake, Kei Yamada","doi":"10.3348/kjr.2025.1743","DOIUrl":"https://doi.org/10.3348/kjr.2025.1743","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145912126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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