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Semaglutide can only be responsible for exercise intolerance and muscle wasting after all other causes have been carefully excluded. 在仔细排除所有其他原因后,Semaglutide只能对运动不耐受和肌肉萎缩负责。
IF 2.6 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2025-12-02 DOI: 10.4082/kjfm.25.0296
Josef Finsterer
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引用次数: 0
The relationship between diet quality, measured by the recommended food score, and depression, assessed using the Patient Health Questionnaire-9: an observational study in Korea. 饮食质量(由推荐食物评分衡量)与抑郁之间的关系,使用患者健康问卷-9进行评估:韩国的一项观察性研究。
IF 2.6 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2025-01-08 DOI: 10.4082/kjfm.24.0204
Sharon Choi, Jung-Sun Lim, Sujeong Han, Jong Seung Kim, Bumjo Oh

Background: Depression is a prevalent mental health disorder that presents substantial public health challenges. Emerging evidence underscores the role of dietary patterns in mitigating depressive symptoms. This study investigated the association between diet quality, assessed using the Recommended Food Score (RFS), and depressive symptoms, evaluated with the Patient Health Questionnaire-9 (PHQ-9), in a sample of Korean adults.

Methods: This cross-sectional study analyzed data from 19,786 participants recruited from a general hospital in Korea, all of whom completed the RFS and PHQ-9 assessments. General characteristics and anthropometric indices were recorded. Statistical analyses included chi-square tests and binary logistic regression to calculate odds ratios (ORs) and 95% confidence intervals for depressive symptoms according to RFS scores, adjusting for potential confounders.

Results: Higher RFS scores were associated with reduced odds of depression in univariate (OR, 0.59; P<0.001) and multivariate (OR, 0.72; P<0.001) analyses. Sociodemographic factors, including older age, higher education, marital status, higher income, professional occupation, and regular exercise, were linked to decreased odds of depression. Conversely, female sex, current smoking, and alcohol consumption were associated with increased odds.

Conclusion: The findings reveal an inverse relationship between diet quality and depressive symptoms among Korean adults, emphasizing the potential of dietary improvements in mental health promotion. Sociodemographic factors significantly influence depression risk. Future studies should adopt longitudinal designs incorporating a wider range of variables to elucidate these complex interactions.

背景:抑郁症是一种普遍存在的精神健康障碍,对公共卫生构成了重大挑战。新出现的证据强调了饮食模式在减轻抑郁症状中的作用。本研究调查了韩国成年人样本中使用推荐食物评分(RFS)评估的饮食质量与使用患者健康问卷-9 (PHQ-9)评估的抑郁症状之间的关系。方法:本横断面研究分析了从韩国一家综合医院招募的19,786名参与者的数据,所有参与者都完成了RFS和PHQ-9评估。记录一般特征和人体测量指标。统计分析包括卡方检验和二元逻辑回归,根据RFS评分计算抑郁症状的优势比(ORs)和95%置信区间,并对潜在混杂因素进行调整。结果:在单变量中,较高的RFS评分与抑郁几率降低相关(OR, 0.59; p)。结论:研究结果揭示了韩国成年人饮食质量与抑郁症状之间的反比关系,强调了饮食改善在促进心理健康方面的潜力。社会人口因素显著影响抑郁风险。未来的研究应采用纵向设计纳入更广泛的变量来阐明这些复杂的相互作用。
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引用次数: 0
Adaptation and validation of the Physical Activity Readiness Questionnaire (PAR-Q)+ 2020 for the Indonesian population: a cross-sectional study. 印度尼西亚人口体力活动准备问卷(PAR-Q)+ 2020的适应和验证:一项横断面研究
IF 2.6 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2025-07-18 DOI: 10.4082/kjfm.24.0288
Iswandy Janetputra Turu' Allo, Arief Wibowo, Badai Bhatara Tiksnadi, Fahmi Nur Hidayatullah, Poundra Adhisatya Pratama, Rizki Bunawan, Nathania Purnomo

Background: The Physical Activity Readiness Questionnaire (PAR-Q)+ 2020 has been utilized to measure readiness for physical activity (PA). However, it is unavailable in the Indonesian language. We aimed to adapt and evaluate the validity and reliability of the PAR-Q+ 2020 culturally for the Indonesian population and its application in general and family medicine.

Methods: We conducted a cross-sectional study to adapt the PAR-Q+ 2020 to the Indonesian language. A face validity interview with 20 participants followed the translation and back-translation processes. Subsequently, an online questionnaire was distributed between June and October 2022, with 378 participants responding and a 72.2% response rate for the second test. Cohen's kappa was calculated to determine the intra-rater reliability of each item. Intra-class correlation (ICC) and Cronbach's alpha analyses were conducted to examine the first and second parts of the questionnaire and the overall intra-rater reliability and internal consistency of the questionnaire.

Results: The median age of the participants was 27 years (range, 18-61 years), and 63% (n=172) were female. The Cohen's kappa value of each item ranged from to 0.801-1.000 (almost perfect to perfect agreement). The ICC values for the first and second parts and the overall questionnaire were 0.957, 0.993, and 0.987, respectively. Cronbach's alpha was adequate for the first part (α=0.958), second part (α=0.993), and overall questionnaire (α=0.987).

Conclusion: The Indonesian version of the PAR-Q+ 2020 demonstrated reliability and preliminary evidence of its validity in measuring individual readiness for PA. Further studies involving a broader population and employing more comprehensive validation methods are necessary to establish its validity and applicability fully.

背景:体育活动准备问卷(PAR-Q)+ 2020已被用于测量体育活动准备(PA)。然而,它没有印尼语版本。我们的目的是适应和评估PAR-Q+ 2020在印尼人口文化上的效度和可靠性及其在普通医学和家庭医学中的应用。方法:我们进行了一项横断面研究,以使PAR-Q+ 2020适应印度尼西亚语言。在翻译和反翻译过程之后,对20名参与者进行了面部效度访谈。随后,在2022年6月至10月期间分发了一份在线问卷,共有378名参与者参与了第二次测试,回复率为72.2%。计算Cohen的kappa来确定每个项目的内部信度。采用类内相关分析(ICC)和Cronbach's alpha分析对问卷的第一部分和第二部分进行检验,并对问卷的整体类内信度和内部一致性进行检验。结果:参与者的中位年龄为27岁(范围18-61岁),63% (n=172)为女性。每个项目的科恩卡帕值范围为0.801-1.000(几乎完全一致)。第一部分、第二部分及整体问卷的ICC值分别为0.957、0.993、0.987。问卷第一部分(α=0.958)、第二部分(α=0.993)和整体(α=0.987)的Cronbach′s α均是适当的。结论:印尼版PAR-Q+ 2020在测量个人PA准备方面具有可靠性和初步有效性证据。进一步的研究涉及更广泛的人群和采用更全面的验证方法是必要的,以充分建立其有效性和适用性。
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引用次数: 0
A cross-sectional study of breakfast skipping and body composition among young adults. 青年人不吃早餐与身体成分的横断面研究。
IF 2.6 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2025-02-26 DOI: 10.4082/kjfm.24.0217
Esther Kim, Kyujin Choi, Su-Min Jeong, Hee-Kyung Joh

Background: Although breakfast provides essential nutrients and energy, skipping this meal has become increasingly common among young adults in Korea. In this study, we examine the relationship between breakfast consumption and body composition.

Methods: We analyzed data from 17,763 students aged 18-39 at Seoul National University (2018-2022). Participants were categorized based on their breakfast frequency: non-skippers, 1 to 3-day skippers, and 4 to 7-day skippers. Measurements included body mass index, waist circumference, body fat percentage, fat mass index (FMI), fat-free mass index (FFMI), and skeletal muscle mass index (SMI). Multivariable logistic and linear regression models adjusted for age, sex, alcohol use, smoking, physical activity, sleep, and food consumption frequencies were used.

Results: Obesity (17.4% vs. 14.8%) and abdominal obesity (10.0% vs. 7.8%) were higher in those skipping breakfast 4 to 7 d/wk compared with non-skippers. Skipping breakfast was not significantly associated with abdominal obesity in either sex. In women, the odds of obesity were higher (odds ratio, 1.57; 95% confidence interval, 1.14-2.15; P=0.006), whereas no significant difference was observed in men. Men who skipped breakfast had increased body fat percentage (coefficient, 0.87; P<0.001) and FMI (coefficient, 0.18; P=0.009) and decreased FFMI and SMI. Women showed increased body fat percentage (coefficient, 0.92; P<0.001) and FMI but no significant differences in FFMI or SMI.

Conclusion: Skipping breakfast adversely affects body composition by increasing body fat percentage and FMI. Further research is needed to confirm these findings and explore the underlying mechanisms.

背景:虽然早餐提供必需的营养和能量,但不吃早餐在韩国的年轻人中越来越普遍。在这项研究中,我们研究了早餐消费与身体成分之间的关系。方法:我们分析了首尔国立大学(2018-2022)17763名18-39岁学生的数据。参与者根据他们的早餐频率进行分类:不吃不吃,1到3天不吃,4到7天不吃。测量包括身体质量指数、腰围、体脂百分比、脂肪质量指数(FMI)、无脂质量指数(FFMI)和骨骼肌质量指数(SMI)。采用多变量logistic和线性回归模型,对年龄、性别、饮酒、吸烟、体力活动、睡眠和食物消费频率进行调整。结果:每周4 - 7天不吃早餐的人肥胖(17.4% vs. 14.8%)和腹部肥胖(10.0% vs. 7.8%)的比例高于不吃早餐的人。无论男女,不吃早餐与腹部肥胖都没有显著关联。在女性中,肥胖的几率更高(优势比,1.57;95%置信区间为1.14-2.15;P=0.006),而男性无显著差异。不吃早餐的男性体脂率增加(系数0.87;结论:不吃早餐通过增加体脂率和FMI对身体成分产生不利影响。需要进一步的研究来证实这些发现并探索潜在的机制。
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引用次数: 0
The relationship between sleep duration and obesity among risky drinking workers: using the Korea National Health and Nutrition Survey. 危险饮酒工人的睡眠时间与肥胖之间的关系:使用韩国国家健康和营养调查。
IF 2.6 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2025-04-08 DOI: 10.4082/kjfm.24.0205
Jion Kim, Sinyoung Cho, Young Ho Yun

Background: The association between sleep duration and obesity risk among risky drinkers remains controversial. This study aims to investigate the relationship between adequate sleep duration and both central and overall obesity among risky drinkers in Korea, with a focus on identifying potential interventions to reduce obesity rates.

Methods: We analyzed data from 978 individuals, selected from 1,356 risky drinkers-as defined by the World Health Organization criteria-who participated in the 2019-2020 Korea National Health and Nutrition Examination Survey. Participants had no missing values and were engaged in economic activities. Demographic characteristics and key variables by obesity status were examined using frequency analysis and chi-square tests. Multivariable logistic regression analysis was performed to explore the association between sleep duration and obesity. To account for the stratified sampling design, we utilized complex sample analysis with weighted values.

Results: Risky drinkers with adequate sleep duration (7-9 hours) were less likely to be obese based on waist circumference (≥90 cm in males; ≥85 cm in females) (odds ratio [OR], 0.64; 95% confidence interval [CI], 0.48-0.86) and body mass index (≥25 kg/m2) (OR, 0.56; 95% CI, 0.41-0.76). Trend analysis revealed a significant inverse relationship between sleep duration and obesity likelihood (P for trend <0.05). Gender-stratified analysis demonstrated that the association was significant among males and more pronounced in risky drinkers compared to the general population.

Conclusion: This study suggests that adequate sleep duration may play a key role in reducing obesity rates among Korean male risky drinkers. Further longitudinal studies are recommended to strengthen this finding.

背景:高危饮酒者的睡眠时间与肥胖风险之间的关系仍然存在争议。本研究旨在调查韩国高危饮酒者中充足的睡眠时间与中心和整体肥胖之间的关系,重点是确定降低肥胖率的潜在干预措施。方法:我们分析了参加2019-2020年韩国国家健康与营养检查调查的1356名高危饮酒者(按照世界卫生组织的标准定义)中978人的数据。参与者没有价值观缺失,并从事经济活动。采用频率分析和卡方检验对肥胖状况的人口统计学特征和关键变量进行检验。采用多变量logistic回归分析探讨睡眠时间与肥胖之间的关系。为了解释分层抽样设计,我们使用加权值的复杂样本分析。结果:睡眠时间充足(7-9小时)的高危饮酒者根据腰围(男性≥90厘米;女性≥85 cm)(优势比[OR], 0.64;95%可信区间[CI], 0.48-0.86)和体重指数(≥25 kg/m2) (OR, 0.56;95% ci, 0.41-0.76)。结论:本研究表明,充足的睡眠时间可能在降低韩国男性高危饮酒者的肥胖率方面发挥关键作用。建议进一步的纵向研究来加强这一发现。
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引用次数: 0
One-year mortality disparities between infants of unmarried and married families in South Korea: a large scale retrospective cohort study. 韩国未婚和已婚家庭婴儿一岁死亡率差异:一项大规模回顾性队列研究。
IF 2.6 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2025-04-16 DOI: 10.4082/kjfm.24.0226
Seonyoung Jeong, Yeani Choi, Hajin Kim, Sang Min Park

Background: This study examined disparities in 1-year mortality rates between infants born to married and unmarried single-parent families, emphasizing the need for targeted health policies.

Methods: Data from 3,298,263 cases, obtained from the South Korea National Statistical Office (2010-2017), were analyzed. T-tests and chi-square tests were used to assess the demographic characteristics of the study group. The number of deaths per 1,000 live births was calculated, and logistic and multivariable logistic regressions were employed to compare infant mortality rates between family types. Additional stratified analyses, based on gestational age and birth weight, further elucidated the relationship between parental marital status and infant mortality.

Results: Infants from unmarried families exhibited a 3.34-fold higher crude odds ratio (OR) for 1-year mortality (95% confidence interval [CI], 2.56-4.36; P<0.001) than that from married families. After adjusting for confounders, the adjusted OR was 1.40 (95% CI, 1.03-1.92). Stratification by gestational age and birth weight revealed crude ORs of 4.62 (95% CI, 3.34- 6.39) in non-preterm infants (≥37 weeks) and 4.76 (95% CI, 3.46-6.56) in non-low-birth-weight infants (≥2.5 kg), highlighting a more pronounced disparity in infants born at or above normal weight and full term. No significant difference (P>0.05) was found in the crude OR for 1-year mortality rates among low-birth-weight (<2.5 kg) or preterm (<37 weeks) infants between the two-family types.

Conclusion: This study highlights the significant disparity in infant mortality rates based on parental marital status, underscoring the need for enhanced social support and tailored policies for unmarried single-parent families.

背景:本研究调查了已婚和未婚单亲家庭所生婴儿1岁死亡率的差异,强调需要有针对性的卫生政策。方法:对2010-2017年韩国国家统计局3298263例病例数据进行分析。采用t检验和卡方检验评估研究组的人口统计学特征。计算每1,000名活产婴儿的死亡人数,并采用logistic和多变量logistic回归来比较不同家庭类型之间的婴儿死亡率。另外,基于胎龄和出生体重的分层分析进一步阐明了父母婚姻状况与婴儿死亡率之间的关系。结果:来自未婚家庭的婴儿1年死亡率的粗优势比(OR)高出3.34倍(95%置信区间[CI], 2.56-4.36;低出生体重儿的1年死亡率(
{"title":"One-year mortality disparities between infants of unmarried and married families in South Korea: a large scale retrospective cohort study.","authors":"Seonyoung Jeong, Yeani Choi, Hajin Kim, Sang Min Park","doi":"10.4082/kjfm.24.0226","DOIUrl":"10.4082/kjfm.24.0226","url":null,"abstract":"<p><strong>Background: </strong>This study examined disparities in 1-year mortality rates between infants born to married and unmarried single-parent families, emphasizing the need for targeted health policies.</p><p><strong>Methods: </strong>Data from 3,298,263 cases, obtained from the South Korea National Statistical Office (2010-2017), were analyzed. T-tests and chi-square tests were used to assess the demographic characteristics of the study group. The number of deaths per 1,000 live births was calculated, and logistic and multivariable logistic regressions were employed to compare infant mortality rates between family types. Additional stratified analyses, based on gestational age and birth weight, further elucidated the relationship between parental marital status and infant mortality.</p><p><strong>Results: </strong>Infants from unmarried families exhibited a 3.34-fold higher crude odds ratio (OR) for 1-year mortality (95% confidence interval [CI], 2.56-4.36; P<0.001) than that from married families. After adjusting for confounders, the adjusted OR was 1.40 (95% CI, 1.03-1.92). Stratification by gestational age and birth weight revealed crude ORs of 4.62 (95% CI, 3.34- 6.39) in non-preterm infants (≥37 weeks) and 4.76 (95% CI, 3.46-6.56) in non-low-birth-weight infants (≥2.5 kg), highlighting a more pronounced disparity in infants born at or above normal weight and full term. No significant difference (P>0.05) was found in the crude OR for 1-year mortality rates among low-birth-weight (<2.5 kg) or preterm (<37 weeks) infants between the two-family types.</p><p><strong>Conclusion: </strong>This study highlights the significant disparity in infant mortality rates based on parental marital status, underscoring the need for enhanced social support and tailored policies for unmarried single-parent families.</p>","PeriodicalId":17893,"journal":{"name":"Korean Journal of Family Medicine","volume":" ","pages":"46-58"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single point insulin sensitivity estimator index is associated with predominance of atherogenic small, dense low-density lipoprotein cholesterol particles in Korean obese adults: a retrospective study. 单点胰岛素敏感性估计指数与韩国肥胖成人动脉粥样硬化小而致密的低密度脂蛋白胆固醇颗粒的优势相关:一项回顾性研究。
IF 2.6 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2025-02-20 DOI: 10.4082/kjfm.24.0202
Jihoon Eor, Yaeji Lee, Yea-Chan Lee, Yu-Jin Kwon, Ji-Won Lee

Background: Insulin resistance (IR) influences lipid metabolism, particularly small dense low-density lipoprotein cholesterol (sdLDL-C), a key feature of diabetic dyslipidemia and a predictor of cardiovascular disease. The single-point insulin sensitivity estimator (SPISE) index is an effective tool for assessing IR. This study explored the relationship between the SPISE index and average low-density lipoprotein cholesterol (LDL-C) particle size in obese Korean adults.

Methods: Cardiovascular risk was assessed in 161 obese individuals. The participants were divided into three groups based on SPISE index tertiles. Steiger's Z test was used to assess the differences in correlation coefficients among various IR indices and average LDL-C particle size. Multivariate linear regression models were used to determine the independent association between the SPISE index and average LDL-C particle size. Receiver operating characteristic (ROC) curves established the SPISE index cut-off for sdLDL-C particle dominance.

Results: The SPISE index was positively correlated with mean LDL-C particle size after adjusting for confounders. It demonstrated a stronger independent association with average LDL-C particle size (r=0.679, P<0.001) than with fasting insulin, the homeostatic model assessment for IR, and the quantitative insulin sensitivity check index (P<0.001 for all). ROC analysis identified an optimal SPISE index cutoff for sdLDL-C predominance of 4.955, with an area under the curve of 0.745.

Conclusion: Our findings indicate a direct correlation between the SPISE index and average LDL-C particle size, suggesting that the SPISE index may complement labor-intensive IR indices and sdLDL-C measurement techniques for estimating IR-induced sdLDL-C predominance.

背景:胰岛素抵抗(IR)影响脂质代谢,尤其是小密度低密度脂蛋白胆固醇(sdLDL-C),这是糖尿病性血脂异常的关键特征,也是心血管疾病的预测因子。单点胰岛素敏感性估计(SPISE)指数是评估IR的有效工具。本研究探讨了韩国肥胖成人SPISE指数与平均低密度脂蛋白胆固醇(LDL-C)颗粒大小之间的关系。方法:对161名肥胖者进行心血管风险评估。根据SPISE指数分类将参与者分为三组。采用Steiger’s Z检验评估各IR指数与LDL-C平均粒径之间相关系数的差异。采用多元线性回归模型确定SPISE指数与平均LDL-C粒径之间的独立关联。受试者工作特征(ROC)曲线建立了sdLDL-C颗粒优势的SPISE指数截止值。结果:调整混杂因素后,SPISE指数与平均LDL-C粒径呈正相关。结论:我们的研究结果表明,SPISE指数与平均LDL-C粒径之间存在直接相关性,这表明SPISE指数可以补充劳动密集型IR指数和sdLDL-C测量技术,用于估计IR诱导的sdLDL-C优势。
{"title":"Single point insulin sensitivity estimator index is associated with predominance of atherogenic small, dense low-density lipoprotein cholesterol particles in Korean obese adults: a retrospective study.","authors":"Jihoon Eor, Yaeji Lee, Yea-Chan Lee, Yu-Jin Kwon, Ji-Won Lee","doi":"10.4082/kjfm.24.0202","DOIUrl":"10.4082/kjfm.24.0202","url":null,"abstract":"<p><strong>Background: </strong>Insulin resistance (IR) influences lipid metabolism, particularly small dense low-density lipoprotein cholesterol (sdLDL-C), a key feature of diabetic dyslipidemia and a predictor of cardiovascular disease. The single-point insulin sensitivity estimator (SPISE) index is an effective tool for assessing IR. This study explored the relationship between the SPISE index and average low-density lipoprotein cholesterol (LDL-C) particle size in obese Korean adults.</p><p><strong>Methods: </strong>Cardiovascular risk was assessed in 161 obese individuals. The participants were divided into three groups based on SPISE index tertiles. Steiger's Z test was used to assess the differences in correlation coefficients among various IR indices and average LDL-C particle size. Multivariate linear regression models were used to determine the independent association between the SPISE index and average LDL-C particle size. Receiver operating characteristic (ROC) curves established the SPISE index cut-off for sdLDL-C particle dominance.</p><p><strong>Results: </strong>The SPISE index was positively correlated with mean LDL-C particle size after adjusting for confounders. It demonstrated a stronger independent association with average LDL-C particle size (r=0.679, P<0.001) than with fasting insulin, the homeostatic model assessment for IR, and the quantitative insulin sensitivity check index (P<0.001 for all). ROC analysis identified an optimal SPISE index cutoff for sdLDL-C predominance of 4.955, with an area under the curve of 0.745.</p><p><strong>Conclusion: </strong>Our findings indicate a direct correlation between the SPISE index and average LDL-C particle size, suggesting that the SPISE index may complement labor-intensive IR indices and sdLDL-C measurement techniques for estimating IR-induced sdLDL-C predominance.</p>","PeriodicalId":17893,"journal":{"name":"Korean Journal of Family Medicine","volume":" ","pages":"20-27"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of common mental disorders in uncontrolled hypertension: a longitudinal study in Bogor City, Indonesia. 常见精神障碍在未控制的高血压中的作用:印度尼西亚茂物市的一项纵向研究。
IF 2.6 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2025-05-22 DOI: 10.4082/kjfm.24.0026
Tri Wurisastuti, Indri Yunita Suryaputri, Rofingatul Mubasyiroh, Wahyu Pudji Nugraheni

Background: The coronavirus disease 2019 (COVID-19) pandemic in Indonesia has led to an increase in mental health problems, especially among those with comorbid hypertension. Uncontrolled hypertension is the primary comorbidity of COVID-19. Thus, this study aimed to determine the pattern of uncontrolled hypertension at two time points during the pandemic and to confirm its relationship with common mental disorders (CMDs).

Methods: This longitudinal study was conducted at two time points (2019 and 2021), and the data of individuals with hypertension was sourced from the Bogor of Noncommunicable Diseases Risk Factors Cohort Study. Data of 1,231 respondents who met the inclusion and exclusion criteria were included in the analyses. The Self-Reported Questionnaire-20 was used to measure CMDs (score of >6). This study used a generalized estimating equation to analyze the data.

Results: The percentage of those with uncontrolled hypertension increased from 57.6% to 66.4%, whereas those with CMDs increased from 6.1% to 11.5%, from 2019 to 2021. The risk of uncontrolled hypertension was higher in patients with CMDs than in those without CMDs. The risk of uncontrolled hypertension increased from twice (adjusted odds ratio [aOR], 1.57; 95% confidence interval [CI], 1.071-2.069) in 2019 to 3 times (aOR, 2.765; 95% CI, 2.243-3.287) in 2021.

Conclusion: Since stress increases the risk of developing uncontrolled hypertension, individuals with hypertension must be able to manage their stress. Apropos this, the governments should provide mental health consultation services in treating patients with hypertension, especially during adverse events such as pandemics.

背景:2019冠状病毒病(COVID-19)在印度尼西亚的大流行导致精神健康问题增加,特别是在合并高血压的人群中。未控制的高血压是COVID-19的主要合并症。因此,本研究旨在确定大流行期间两个时间点不受控制的高血压模式,并确认其与常见精神障碍(cmd)的关系。方法:本纵向研究在2019年和2021年两个时间点进行,高血压患者的数据来自茂物非传染性疾病危险因素队列研究。符合纳入和排除标准的1231名受访者的数据被纳入分析。采用自报问卷-20进行CMDs测量(bbb6分)。本研究采用广义估计方程对数据进行分析。结果:从2019年到2021年,高血压未控制的比例从57.6%上升到66.4%,而慢性阻塞性肺病的比例从6.1%上升到11.5%。冠心病患者发生高血压失控的风险高于无冠心病患者。高血压不受控制的风险从2倍增加(校正优势比[aOR], 1.57;95%置信区间[CI], 1.071-2.069)为2019年的3倍(aOR, 2.765;95% CI, 2.243-3.287)。结论:由于压力增加了发展为不受控制的高血压的风险,高血压患者必须能够控制他们的压力。为此,各国政府应在治疗高血压患者时提供心理健康咨询服务,特别是在发生诸如流行病等不良事件时。
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引用次数: 0
Effect of saffron on premenstrual syndrome and dysmenorrhea: a systematic review and meta-analysis. 藏红花对经前期综合征和痛经的影响:系统综述和荟萃分析。
IF 2.6 Q4 PRIMARY HEALTH CARE Pub Date : 2026-01-01 Epub Date: 2025-10-28 DOI: 10.4082/kjfm.24.0259
Mohammad Mehdi Mohammadi, Zohreh Karimi

Background: Premenstrual syndrome (PMS) and dysmenorrhea are common symptoms in women. In this study, we investigated the effects of saffron on PMS and dysmenorrhea in women.

Methods: In this systematic review and meta-analysis, we comprehensively screened a range of databases, including PubMed, Web of Science, and Science Direct. We included randomized clinical trials investigating the effects of saffron on PMS or dysmenorrhea. Quality assessment of the identified studies was conducted using the Cochrane risk-of-bias assessment tool. Meta-analysis was performed using Comprehensive Meta-Analysis software ver. 2 based on the random effects model.

Results: Meta-analysis revealed that saffron had a significant positive effect on the symptoms of PMS in women (standardized mean difference [SMD], -0.64; 95% confidence interval [CI], -0.84 to -0.44). Furthermore, saffron was effective in reducing dysmenorrhea (SMD, -0.51; 95% CI, -1.01 to -0.01).

Conclusion: The findings of our meta-analysis indicate that saffron exerts beneficial effects on the symptoms of both PMS and dysmenorrhea in women.

背景:经前综合征(PMS)和痛经是女性常见的症状。在本研究中,我们研究了藏红花对女性经前症候群和痛经的影响。方法:在本系统综述和荟萃分析中,我们全面筛选了一系列数据库,包括PubMed、Web of Science和Science Direct。我们纳入了调查藏红花对经前症候群或痛经影响的随机临床试验。使用Cochrane偏倚风险评估工具对已确定的研究进行质量评估。采用综合meta分析软件进行meta分析。2基于随机效应模型。结果:荟萃分析显示,藏红花对女性经前综合症的症状有显著的积极作用(标准化平均差[SMD], -0.64; 95%可信区间[CI], -0.84至-0.44)。此外,藏红花可有效减轻痛经(SMD, -0.51; 95% CI, -1.01至-0.01)。结论:我们的荟萃分析结果表明,藏红花对女性经前症候群和痛经症状都有有益的作用。
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引用次数: 0
A randomized controlled trial comparing home-based modified Epley maneuver and Brandt-Daroff exercise for posterior canal benign paroxysmal positional vertigo symptoms. 一项比较家庭改良Epley手法和Brandt-Daroff手法治疗后椎管良性阵发性位置性眩晕症状的随机对照试验。
IF 2.6 Q4 PRIMARY HEALTH CARE Pub Date : 2025-12-30 DOI: 10.4082/kjfm.24.0337
Nor Hanim Mohamad Hanapi, Nurul Firdausi Hasnol Basri, Adi Rizal Abdul Rahman, Mohd Zulkiflee Abu Bakar, Nor Asiah Muhamad, Mazlina Mazlan, Chung Tze Yang

Background: This study aimed to compare the effects of two home-based exercises, the self-Epley maneuver (SEM) and Brandt-Daroff exercise (BDE), in patients with posterior canal benign paroxysmal positional vertigo (BPPV).

Methods: A total of 50 outpatients with unilateral posterior canal BPPV, a documented positive Dix-Hallpike test, and symptoms of vertigo for a duration of at least 1 week were randomized into the SEM and BDE groups. Patients in both groups performed home-based exercises for a total duration of 2 weeks. The primary outcome was vertigo resolution at 1 and 6 months. Secondary outcomes included conversion of a positive to a negative Dix-Hallpike test at 1 month and reduction in vertigo intensity and Dizziness Handicap Inventory (DHI) scores at 1 month and 6 months.

Results: Vertigo resolution was achieved in 40% of the patients at 1 month and in 48% at 6 months in both groups. The conversion rates from positive to negative Dix-Hallpike test at 1 month were 92% and 84% in the SEM and BDE groups, respectively. There was a significant reduction in the vertigo intensity and an improvement in the mean DHI score. Both SEM and BDE were well tolerated, with a few minor complications, such as transient dizziness and nausea.

Conclusion: Both SEM and BDE are effective for treating posterior canal BPPV. Although there was no significant resolution of the vertigo, there was a reduction in its intensity and a perceived decrease in its negative impact on daily life.

背景:本研究旨在比较两种基于家庭的运动,即自我epley运动(SEM)和Brandt-Daroff运动(BDE)对后管良性阵发性位置性眩晕(BPPV)患者的效果。方法:将50例单侧后管BPPV、Dix-Hallpike试验阳性、眩晕症状持续至少1周的门诊患者随机分为SEM组和BDE组。两组患者均进行为期2周的居家锻炼。主要观察指标为1个月和6个月的眩晕缓解。次要结果包括1个月时Dix-Hallpike试验阳性转化为阴性,1个月和6个月时眩晕强度和头晕障碍量表(DHI)评分降低。结果:两组患者在治疗1个月时眩晕消退率为40%,6个月时为48%。SEM组和BDE组1个月时Dix-Hallpike试验阳性到阴性的转换率分别为92%和84%。眩晕强度显著降低,DHI平均评分改善。SEM和BDE的耐受性都很好,只有一些轻微的并发症,如短暂的头晕和恶心。结论:SEM和BDE治疗后管BPPV均有较好的疗效。虽然眩晕没有明显的缓解,但其强度有所降低,对日常生活的负面影响也有所减少。
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引用次数: 0
期刊
Korean Journal of Family Medicine
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