Pub Date : 2024-08-01DOI: 10.1016/S1474-4422(24)00283-7
The Lancet Neurology
{"title":"A real chance to reduce death and disability from stroke.","authors":"The Lancet Neurology","doi":"10.1016/S1474-4422(24)00283-7","DOIUrl":"10.1016/S1474-4422(24)00283-7","url":null,"abstract":"","PeriodicalId":17989,"journal":{"name":"Lancet Neurology","volume":"23 8","pages":"749"},"PeriodicalIF":45.5,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141727323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-06-13DOI: 10.1016/S1474-4422(24)00258-8
Kazunori Toyoda
{"title":"Tenecteplase versus alteplase in stroke thrombolysis: the last piece of the puzzle?","authors":"Kazunori Toyoda","doi":"10.1016/S1474-4422(24)00258-8","DOIUrl":"10.1016/S1474-4422(24)00258-8","url":null,"abstract":"","PeriodicalId":17989,"journal":{"name":"Lancet Neurology","volume":" ","pages":"750-751"},"PeriodicalIF":45.5,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141331366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-06-21DOI: 10.1016/S1474-4422(24)00264-3
Joanna M Roy, Stavropoula Tjoumakaris
{"title":"Bailout angioplasty or stenting for large vessel occlusion.","authors":"Joanna M Roy, Stavropoula Tjoumakaris","doi":"10.1016/S1474-4422(24)00264-3","DOIUrl":"10.1016/S1474-4422(24)00264-3","url":null,"abstract":"","PeriodicalId":17989,"journal":{"name":"Lancet Neurology","volume":" ","pages":"753-754"},"PeriodicalIF":45.5,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141446478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01DOI: 10.1016/S1474-4422(24)00209-6
Karnig Kazazian, Brian L Edlow, Adrian M Owen
Advances over the past two decades in functional neuroimaging have provided new diagnostic and prognostic tools for patients with severe brain injury. Some of the most pertinent developments in this area involve the assessment of residual brain function in patients in the intensive care unit during the acute phase of severe injury, when they are at their most vulnerable and prognosis is uncertain. Advanced neuroimaging techniques, such as functional MRI and EEG, have now been used to identify preserved cognitive processing, including covert conscious awareness, and to relate them to outcome in patients who are behaviourally unresponsive. Yet, technical and logistical challenges to clinical integration of these advanced neuroimaging techniques remain, such as the need for specialised expertise to acquire, analyse, and interpret data and to determine the appropriate timing for such assessments. Once these barriers are overcome, advanced functional neuroimaging technologies could improve diagnosis and prognosis for millions of patients worldwide.
{"title":"Detecting awareness after acute brain injury.","authors":"Karnig Kazazian, Brian L Edlow, Adrian M Owen","doi":"10.1016/S1474-4422(24)00209-6","DOIUrl":"10.1016/S1474-4422(24)00209-6","url":null,"abstract":"<p><p>Advances over the past two decades in functional neuroimaging have provided new diagnostic and prognostic tools for patients with severe brain injury. Some of the most pertinent developments in this area involve the assessment of residual brain function in patients in the intensive care unit during the acute phase of severe injury, when they are at their most vulnerable and prognosis is uncertain. Advanced neuroimaging techniques, such as functional MRI and EEG, have now been used to identify preserved cognitive processing, including covert conscious awareness, and to relate them to outcome in patients who are behaviourally unresponsive. Yet, technical and logistical challenges to clinical integration of these advanced neuroimaging techniques remain, such as the need for specialised expertise to acquire, analyse, and interpret data and to determine the appropriate timing for such assessments. Once these barriers are overcome, advanced functional neuroimaging technologies could improve diagnosis and prognosis for millions of patients worldwide.</p>","PeriodicalId":17989,"journal":{"name":"Lancet Neurology","volume":"23 8","pages":"836-844"},"PeriodicalIF":45.5,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141727331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/S1474-4422(24)00217-5
Fred B Ketchum, Nathaniel A Chin
{"title":"Concerns with the new biological research criteria for synucleinopathy.","authors":"Fred B Ketchum, Nathaniel A Chin","doi":"10.1016/S1474-4422(24)00217-5","DOIUrl":"10.1016/S1474-4422(24)00217-5","url":null,"abstract":"","PeriodicalId":17989,"journal":{"name":"Lancet Neurology","volume":"23 7","pages":"659"},"PeriodicalIF":45.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141321125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/S1474-4422(24)00176-5
Michel Goedert, Christian Griesinger, Tiago F Outeiro, Roland Riek, Gunnar F Schröder, Maria Grazia Spillantini
{"title":"Abandon the NAC in α-synuclein.","authors":"Michel Goedert, Christian Griesinger, Tiago F Outeiro, Roland Riek, Gunnar F Schröder, Maria Grazia Spillantini","doi":"10.1016/S1474-4422(24)00176-5","DOIUrl":"10.1016/S1474-4422(24)00176-5","url":null,"abstract":"","PeriodicalId":17989,"journal":{"name":"Lancet Neurology","volume":"23 7","pages":"669"},"PeriodicalIF":45.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141321118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/S1474-4422(24)00233-3
Tanya Simuni, Lana M Chahine, Daniel Weintraub, Kathleen M Poston, Catherine M Kopil, Billy Dunn, Kenneth Marek
{"title":"Concerns with the new biological research criteria for synucleinopathy - Authors' reply.","authors":"Tanya Simuni, Lana M Chahine, Daniel Weintraub, Kathleen M Poston, Catherine M Kopil, Billy Dunn, Kenneth Marek","doi":"10.1016/S1474-4422(24)00233-3","DOIUrl":"10.1016/S1474-4422(24)00233-3","url":null,"abstract":"","PeriodicalId":17989,"journal":{"name":"Lancet Neurology","volume":"23 7","pages":"663-666"},"PeriodicalIF":45.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141321120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/S1474-4422(24)00226-6
Maurits K A van Selms, Michiel W van der Linden, Conny van der Meijden, Frank Lobbezoo
{"title":"A call for optimal oral care in patients with ALS.","authors":"Maurits K A van Selms, Michiel W van der Linden, Conny van der Meijden, Frank Lobbezoo","doi":"10.1016/S1474-4422(24)00226-6","DOIUrl":"10.1016/S1474-4422(24)00226-6","url":null,"abstract":"","PeriodicalId":17989,"journal":{"name":"Lancet Neurology","volume":"23 7","pages":"670"},"PeriodicalIF":45.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141321117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}