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A Comparison of Bone Scan Using between F-18 NaF PET/CT and Tc-99m MDP F-18 NaF PET/CT与Tc-99m MDP骨扫描的比较
Pub Date : 2019-03-11 DOI: 10.46475/ASEANJR.V19I2.25
P. Pusuwan, T. Ekjeen, C. Tocharoenchai, Kobkun Maungsomboon, K. Wiyaporn, C. Komoltri, A. Ruangma, Ruentip Tiparoj
Objective: To study bone scintigraphy using between F-18 NaF PET/CT and Tc-99m MDP scan for detecting bone metastases. Material and Methods: Thirteen patients (5 males, mean age 55.4 years, range 34-74 years) who were suspected bone metastases with single or two equivocal lesions on Tc-99m MDP bone scan were recruited between October 2010 and October 2012. All these patients underwent F-18 NaF PET/CT scan within one week after Tc-99m MDP bone scan. The sensitivity, specificity and accuracy of Tc-99m MDP bone scan and F-18 NaF PET/CT in differentiating metastatic bone lesion from benign lesion by patientbased and lesion-based analyses were studied. Results: F-18 NaF PET/CT could identify all seven patients with malignant bone metastases that Tc-99m MDP bone scan was interpreted as malignancy in only three patients (42.9%) and equivocal in the rest of these patients. For lesion-based analysis of the overall 75 lesions, the sensitivity, specificity and accuracy of Tc-99m MDP bone scan were 48%, 83.3% and 70.7% and F-18 NaF PET/CT were 100% for all parameters. Besides the ability of F-18 NaF PET/CT to accurately identify malignancy from benign lesion, unenhanced CT portion of PET/CT can show extra-osseous findings that may change patient management. Conclusion: F-18 NaF PET/CT provides an excellent bone image quality and higher accuracy than Tc-99m MDP bone scan. Then F-18 NaF PET/CT is a good choice for evaluating bone metastases.
目的:探讨F-18 NaF PET/CT与Tc-99m MDP骨显像对骨转移的检测价值。材料与方法:2010年10月至2012年10月,在Tc-99m MDP骨扫描中,13例疑似骨转移患者(男性5例,平均年龄55.4岁,年龄范围34-74岁)伴有单个或两个模棱两可病灶。所有患者在Tc-99m MDP骨扫描后一周内进行F-18 NaF PET/CT扫描。研究Tc-99m MDP骨扫描和F-18 NaF PET/CT鉴别转移性骨病变与良性骨病变的敏感性、特异性和准确性。结果:F-18 NaF PET/CT能识别所有7例恶性骨转移患者,Tc-99m MDP骨扫描仅3例(42.9%)被解释为恶性,其余患者解释不明确。对75个病灶进行基于病灶的分析,Tc-99m MDP骨扫描的敏感性、特异性和准确性分别为48%、83.3%和70.7%,F-18 NaF PET/CT的所有参数均为100%。除了F-18 NaF PET/CT能够准确识别良性病变和恶性病变外,PET/CT未增强部分可以显示可能改变患者治疗的骨外表现。结论:F-18 NaF PET/CT具有较好的骨成像质量和准确性,优于Tc-99m MDP骨扫描。因此,F-18 NaF PET/CT是评估骨转移的良好选择。
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引用次数: 0
Blunt Traumatic Diaphragmatic Hernia: Case Report 创伤性钝性膈疝1例
Pub Date : 2019-03-11 DOI: 10.46475/aseanjr.v19i2.32
Siwipan Changtham
Case Report A 55-year old man visited the orthopedic OPD due to tenderness and swelling at left ankle from a motorcycle accident, 3 hours before. Left medial malleolus fracture was diagnosed. A short leg cast was performed by orthopedist. During the wait to receive his medicines, he had sudden onset of chest discomfort, pain at left lower chest and left upper abdomen. He was sent to the ER department. He had blood pressure of 110/75 mmHg, pulse rate of 64 beats/min, respiratory rate of 20 breaths/min and oxygen saturation of 97%. A physical examination found mild pale conjunctiva, tender at left chest wall, equal breath sounds. Mild tenderness at LUQ was also noted without guarding or rebound tenderness. Chest film showed air-fluid level within left hemithorax and mild shifting of mediastinum to the right. A CT chest including upper abdomen with contrast study was performed. Discontinuity of left hemidiaphargm with herniation of stomach and duodenum into left hemithorax was seen. Splenic laceration and minimal left hemothorax were also noted. He was admitted at the traumatic surgery ward for an exploratory laparotomy. Rupture of left hemidiaphragm, approximately 10 cm in diameter, with herniation of stomach, duodenum and omentum into left thorax was found. Left hemothorax and splenic contusion were also found. Repair to left diaphragm with interrupted non-absorptable sutures was performed. No evidence of complication was detected.
病例报告一名55岁男性因摩托车事故左脚踝压痛和肿胀3小时前来骨科门诊就诊。诊断为左内踝骨折。矫形外科医生给小腿打了石膏。在等待服药期间,他突然感到胸部不适,左下胸和左上腹部疼痛。他被送到急诊室了。血压110/75 mmHg,脉搏64次/分,呼吸频率20次/分,血氧饱和度97%。查体发现结膜轻度苍白,左胸壁触痛,呼吸音均等。轻度压痛在LUQ也注意到没有保护或反弹压痛。胸片显示左半胸内气液平,纵膈轻度右移。行胸部及上腹部CT对比检查。左半膈不连续,胃和十二指肠疝入左半胸。脾裂伤及轻微左胸血。他在创伤外科病房接受剖腹探查手术。左膈破裂,直径约10cm,胃、十二指肠及大网膜疝入左胸。左胸积血,脾挫伤。用中断的不可吸收缝线修复左膈。没有发现并发症的证据。
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引用次数: 0
Diagnostic Efficacy of CT/MR Imaging and Adrenal Vein Sampling for Localization of Aldosterone-producing Adrenal Adenomas in Primary Aldosteronism 原发性醛固酮增多症中产生醛固酮的肾上腺腺瘤的CT/MR成像及肾上腺静脉取样诊断价值
Pub Date : 1900-01-01 DOI: 10.46475/aseanjr.v19i2.26
Nontika Boontankan, Kewalee Sasiwimonphan
Objective: To test the sensitivity, specificity, accuracy, positive predictive value (PPV) and negative predictive value (NPV) of CT/MR imaging and adrenal vein sampling (AVS) for diagnosis of aldosterone-producing adrenal adenoma (APA). Material and method: Retrospective study of 14 patients with primary hyperaldosteronism (PAL) who underwent both CT/MR imaging and AVS between June 2007 and June 2012 were performed. The study included 7 male and 7 female patients. Review CT/MR findings of these cases and compared with AVS results were done. Results: Five of fourteen patients (35%) had unilateral adrenal nodules on CT, and one of fourteen patients (7.1%) had bilateral adrenal nodules on CT[D1]. The remaining eight patients had no significant nodules in both adrenal glands. Among 5 patients who had unilateral adrenal nodule detected from CT, 4 patients (80%) with nodule greater than 10 mm also presented with lateralization from AVS and finally pathological proven APA. The last patient with unilateral nodule showed small size less than 10 mm and had AVS results of bilateral lesion. Medical therapy was applied for this patient instead of surgical treatment. In other group (8 of 14 patients, 57.1%), there was no significant nodule from CT or MRI and AVS results indicated bilateral lesions in two patients (25%). The rest of six patients found unilateral lesion on AVS which underwent adrenalectomy and histological revealed adrenal hyperplasia of all cases. Two of six patients concluded to be primary adrenal hyperplasia (PAH) or unilateral adrenal hyperplasia (UAH), which showed clinical cure after adenalectomy. The remaining four patients who showed no improvement of hypertension after adrenalectomy concluded to be bilateral adrenal hyperplasia (BAH). The sensitivity, specificity, accuracy, PPV and NPV for detected adrenal adenoma by CT/MRI of our study were 66.67%, 87.50%, 78.57%, 80.00%, and 77.78%, respectively. The sensitivity, specificity, accuracy, PPV and NPV for detected adrenal adenoma by AVS at cut point AVS ratio at 2 were 100%, 50%, 71.43%, 60% and 100%, respectively. Conclusion: In patient with suspected PAL who presented with unilateral adrenal nodule at least 10 mm in size detected by CT, these patient should be referred for adrenalectomy without need to performing AVS. The differentiation of subtype in patients with PAL is most reliably achieved with AVS which may reserve for patient who had no significant adrenal nodule from CT/MRI.
目的:探讨CT/MR成像及肾上腺静脉取样(AVS)诊断醛固酮生成性肾上腺腺瘤(APA)的敏感性、特异性、准确性、阳性预测值(PPV)和阴性预测值(NPV)。材料与方法:回顾性分析2007年6月至2012年6月14例原发性醛固酮增多症(PAL)患者行CT/MR及AVS检查。该研究包括7名男性和7名女性患者。回顾这些病例的CT/MR表现,并与AVS结果进行比较。结果:14例患者中有5例(35%)CT表现为单侧肾上腺结节,1例(7.1%)CT表现为双侧肾上腺结节[D1]。其余8例患者双肾上腺均未见明显结节。CT显示单侧肾上腺结节的5例患者中,结节大于10 mm的4例(80%)在AVS上也出现偏侧,最终病理证实为APA。最后一例单侧结节大小小于10mm,双侧病变AVS结果。对这个病人进行了药物治疗而不是手术治疗。另一组(14例患者中8例,57.1%)CT或MRI未见明显结节,AVS结果显示2例患者双侧病变(25%)。其余6例患者均发现单侧AVS病变,行肾上腺切除术,组织学均显示肾上腺增生。6例患者中2例诊断为原发性肾上腺增生(PAH)或单侧肾上腺增生(UAH),经腺切除术后临床治愈。其余4例患者在肾上腺切除术后高血压没有改善,结论是双侧肾上腺增生(BAH)。本研究CT/MRI检测肾上腺腺瘤的敏感性、特异性、准确性、PPV和NPV分别为66.67%、87.50%、78.57%、80.00%和77.78%。AVS在切点AVS比值为2时检测肾上腺腺瘤的敏感性为100%,特异性为50%,准确性为71.43%,PPV为60%,NPV为100%。结论:CT表现为单侧肾上腺结节≥10mm的疑似PAL患者应行肾上腺切除术,无需行AVS。在PAL患者中,AVS最可靠地实现了亚型的区分,这可能保留给CT/MRI没有明显肾上腺结节的患者。
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引用次数: 0
Reversible Cerebral Vasoconstriction Syndrome: A Commonly Missed Diagnosis in Acute Severe Headaches 可逆性脑血管收缩综合征:急性严重头痛的常见漏诊
Pub Date : 1900-01-01 DOI: 10.46475/aseanjr.v19i2.34
S. Hirunpat, N. Sanghan, Adchara Wanai, N. Ina, Pornrujee Hirunpat
Summary: In spite of the recent acceptance to be a common cause of acute severe headaches, reversible cerebral vasoconstriction syndrome (RCVS) is still commonly missed. The syndrome is characterized by acute severe headaches due to the vasoconstriction of the cerebral arteries, which eventually resolve spontaneously. We present a reported case of RCVS with a typical magnetic resonance angiography (MRA) appearance and a review of the literature.
摘要:尽管最近被认为是急性严重头痛的常见原因,可逆性脑血管收缩综合征(RCVS)仍然经常被忽视。该综合征的特点是急性严重头痛,由于大脑动脉血管收缩,最终自行解决。我们报告了一例具有典型磁共振血管造影(MRA)表现的RCVS,并对文献进行了回顾。
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引用次数: 1
Unsatisfactory Ultrasound-Guided Fine Needle Aspiration of Thyroid Nodule: Which Factors Limit Cytology Result? 超声引导甲状腺结节细针穿刺效果不理想:哪些因素限制了细胞学结果?
Pub Date : 1900-01-01 DOI: 10.46475/aseanjr.v19i2.27
P. Poonotoke
Objective: The purpose of this study is to focus on which factors affect or limit fine-needle aspirationcytology (FNAC) results of thyroid nodule, in order to increase the satisfactory cytologic results and to avoid unnecessary FNAC in patients with asymptomatic benign nodules and highly possible unsatisfactory results. Materials and Methods: The records of 217 thyroid nodules in 179 patients referred to the radiology department at Lerdsin Hospital for US-guided FNAC between January 2010 and December 2013 were retrospectively reviewed. Cytologic specimens of the FNAC were classified as unsatisfactory (non-diagnostic) and satisfactory (diagnostic) results and analyzed by mean of Logistic regression analysis, based on patientûs age, gender, nodule size, number and solid-cystic composition of nodule. Results: The cytologic result was satisfactory for diagnosis in 154 specimens (71%) and unsatisfactory in 63 specimens (29%). Patientûs age, gender, number and size of nodule of the unsatisfactory result group were not different from the satisfactory result group but the nodule composition was different. Percentage of the unsatisfactory aspiration increased as the cystic component increased, ranging from 15.3% in solid nodules to 59.3% in predominant cystic nodules (cystic >75%). Upon the binary logistic regression analysis, the predominant cystic nodule was the only significant predictor of unsatisfactory result (p-value < 0.001) while solid nodules, predominant solid nodules and solid-cystic nodules are not significant. Unsatisfactory FNAC result of the predominant cystic nodules was about 8 times higher than the solid nodule (crude odds ratio = 8.087, p-value < 0.001). Conclusion: To optimize the usefulness of FNAC,we should realize that solid-cystic composition of the thyroid nodules influence the non-diagnostic and diagnostic cytology.
目的:探讨影响或限制甲状腺结节细针穿刺细胞学检查(FNAC)结果的因素,以提高满意的细胞学检查结果,避免无症状良性结节患者进行不必要的FNAC检查和可能出现的不满意结果。材料与方法:回顾性分析2010年1月至2013年12月在Lerdsin医院放射科行us引导FNAC的179例患者的217例甲状腺结节的记录。根据患者的年龄、性别、结节大小、数量及结节的实囊性组成,将FNAC细胞学标本分为不满意(非诊断性)和满意(诊断性)两类,采用Logistic回归分析。结果:细胞学检查结果满意154例(71%),不满意63例(29%)。结果不满意组患者的年龄、性别、结节数目和大小与结果满意组无显著差异,但结节组成不同。随着囊性成分的增加,不满意抽吸的比例也随之增加,实性结节为15.3%,显性结节为59.3%(囊性>75%)。在二元logistic回归分析中,显性囊性结节是唯一不满意结果的显著预测因子(p值< 0.001),而实性结节、显性实性结节和实性囊性结节均不显著。显性囊性结节的FNAC不满意率约为实性结节的8倍(粗优势比= 8.087,p值< 0.001)。结论:为了优化FNAC的有效性,我们应该认识到甲状腺结节的实囊性组成对非诊断性和诊断性细胞学的影响。
{"title":"Unsatisfactory Ultrasound-Guided Fine Needle Aspiration of Thyroid Nodule: Which Factors Limit Cytology Result?","authors":"P. Poonotoke","doi":"10.46475/aseanjr.v19i2.27","DOIUrl":"https://doi.org/10.46475/aseanjr.v19i2.27","url":null,"abstract":"Objective: The purpose of this study is to focus on which factors affect or limit fine-needle aspirationcytology (FNAC) results of thyroid nodule, in order to increase the satisfactory cytologic results and to avoid unnecessary FNAC in patients with asymptomatic benign nodules and highly possible unsatisfactory results. \u0000Materials and Methods: The records of 217 thyroid nodules in 179 patients referred to the radiology department at Lerdsin Hospital for US-guided FNAC between January 2010 and December 2013 were retrospectively reviewed. Cytologic specimens of the FNAC were classified as unsatisfactory (non-diagnostic) and satisfactory (diagnostic) results and analyzed by mean of Logistic regression analysis, based on patientûs age, gender, nodule size, number and solid-cystic composition of nodule. \u0000Results: The cytologic result was satisfactory for diagnosis in 154 specimens (71%) and unsatisfactory in 63 specimens (29%). Patientûs age, gender, number and size of nodule of the unsatisfactory result group were not different from the satisfactory result group but the nodule composition was different. Percentage of the unsatisfactory aspiration increased as the cystic component increased, ranging from 15.3% in solid nodules to 59.3% in predominant cystic nodules (cystic >75%). Upon the binary logistic regression analysis, the predominant cystic nodule was the only significant predictor of unsatisfactory result (p-value < 0.001) while solid nodules, predominant solid nodules and solid-cystic nodules are not significant. Unsatisfactory FNAC result of the predominant cystic nodules was about 8 times higher than the solid nodule (crude odds ratio = 8.087, p-value < 0.001). \u0000Conclusion: To optimize the usefulness of FNAC,we should realize that solid-cystic composition of the thyroid nodules influence the non-diagnostic and diagnostic cytology.","PeriodicalId":180936,"journal":{"name":"The ASEAN Journal of Radiology","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124197753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computed Tomography Analysis of the Ethmoid Roof: A Region at Risk in Endoscopic Sinus Injury 筛顶的计算机断层分析:内镜下鼻窦损伤的危险区域
Pub Date : 1900-01-01 DOI: 10.46475/aseanjr.v19i2.28
Pra Urusopone
Objective: To determine the olfactory fossa depth according to the Keros classification and determine the incidence of asymmetry in height and configuration of the ethmoid roof. Materials and Methods: Retrospective analysis of 75 coronal computed tomography studies of paranasal sinuses and facial bones were performed. Measurement of the depth of the lateral lamella, classification of the depth according to Keros type and determination of the asymmetries in the ethmoid roof depth and configuration were done. Results: The mean height of the lateral lamella cribiform plate (LLCP) was 2.15+1.29 mm. The cases were classified as 87.33% Keros type1 and 12.67 % as Keros type 2. No Keros type 3 was found .There was asymmetry in the LLCP height of 33.33% of cases and a configuration asymmetry in 8% of the cases. No significant difference between the mean height and distribution of Keros type between gender and laterality were also found. Conclusion: As regards the olfactory fossa depth, the Keros type 1 was most frequently found. Asymmetry in the depth and configuration were detected in 33.33 and 8% respectively. Risk of inadvertent intracranial entry through the lateral lamella among Thai may be lower than other studies with majority of cases classified as Keros type 2 or 3.
目的:根据Keros分类确定嗅窝深度,确定筛顶高度和形态不对称的发生率。材料和方法:回顾性分析75例鼻窦和面骨的冠状位计算机断层扫描研究。测量侧板深度,根据Keros类型进行深度分类,确定筛顶深度和形态的不对称性。结果:侧板筛板(LLCP)平均高度为2.15+1.29 mm。Keros 1型占87.33%,Keros 2型占12.67%。未发现Keros 3型。33.33%的病例LLCP高度不对称,8%的病例LLCP形态不对称。Keros型的平均高度和分布在性别和侧位之间也没有显著差异。结论:在嗅窝深度方面,Keros 1型最为常见。深度不对称占33.33%,形态不对称占8%。泰国人无意中通过外侧椎板进入颅内的风险可能低于其他研究,大多数病例被归类为Keros 2型或3型。
{"title":"Computed Tomography Analysis of the Ethmoid Roof: A Region at Risk in Endoscopic Sinus Injury","authors":"Pra Urusopone","doi":"10.46475/aseanjr.v19i2.28","DOIUrl":"https://doi.org/10.46475/aseanjr.v19i2.28","url":null,"abstract":"Objective: To determine the olfactory fossa depth according to the Keros classification and determine the incidence of asymmetry in height and configuration of the ethmoid roof. \u0000Materials and Methods: Retrospective analysis of 75 coronal computed tomography studies of paranasal sinuses and facial bones were performed. Measurement of the depth of the lateral lamella, classification of the depth according to Keros type and determination of the asymmetries in the ethmoid roof depth and configuration were done. \u0000Results: The mean height of the lateral lamella cribiform plate (LLCP) was 2.15+1.29 mm. The cases were classified as 87.33% Keros type1 and 12.67 % as Keros type 2. No Keros type 3 was found .There was asymmetry in the LLCP height of 33.33% of cases and a configuration asymmetry in 8% of the cases. No significant difference between the mean height and distribution of Keros type between gender and laterality were also found. \u0000Conclusion: As regards the olfactory fossa depth, the Keros type 1 was most frequently found. Asymmetry in the depth and configuration were detected in 33.33 and 8% respectively. Risk of inadvertent intracranial entry through the lateral lamella among Thai may be lower than other studies with majority of cases classified as Keros type 2 or 3.","PeriodicalId":180936,"journal":{"name":"The ASEAN Journal of Radiology","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126392278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumefactive Multiple Sclerosis Clinically Mimicking Acute Stroke and Lesional Migration Along the Biopsy Tract: A Case Report 肿瘤性多发性硬化症临床模拟急性脑卒中及沿活检道病变转移一例报告
Pub Date : 1900-01-01 DOI: 10.46475/aseanjr.v19i2.33
O. Tritanon, Arunee Singhsnaeh, Jiraporn Laothamatus, A. Boongird, D. Ratanakorn, P. Nitiyanant
Tumefactive multiple sclerosis is a form of demyelinating disease which patient can present with acute stroke. We reported a case of a 49-year-old woman with well controlled hypertension, who presented with right hemiplegia 15 hours prior to admission. The initial diagnosis of acute stroke was made. Emergency computed tomography showed hypodense lesion at the left lentiform nucleus and posterior limb of the left internal capsule. The magnetic resonance imaging (MRI) study showed hyperintense FLAIR lesion in the left lentiform nucleus, left internal capsule, left thalamus, and periventricular area of the left frontoparietal region, some areas of restricted diffusion and inhomogeneous enhancement. The MR spectroscopy (MRS) of the lesion showed increased choline peak, decreased creatine and NAA peaks, and maximal choline to creatine ratio 2.25. Her symptoms deteriorated with progressive headache and motor aphasia. The follow up MRI showed extension of the inhomogeneous enhancing lesion along the biopsy tract at the left frontal lobe with the enhancing and MR spectra pattern similar to the lesion. The craniotomy with left frontal lesion excision included the mass and the biopsy tract was done. The lesion showed acute and chronic inflammatory cell infiltration with macrophages, necrotic tissue and reactive gliosis. The further pathological worked up demonstrated foci of demyelination with relative axonal preservation, numerous CD68+ macrophages with intracyto-plasmic Luxol fast blue(+) myelin debris. Perivascular and parenchymal CD3+ T-cells were identified, especially in demyelinating foci. These findings supported the diagnosis of tumefactive multiple sclerosis. Her conditions were improved after treating with pulse methylprednisolone and intravenous immunoglobulin (IVIG). Follow up MRI study 4 months after treatment revealed almost resolution of the preexisting inhomogeneous enhancing lesion.
肿瘤性多发性硬化症是脱髓鞘疾病的一种,患者可表现为急性中风。我们报告了一例49岁女性高血压控制良好,入院前15小时出现右偏瘫。初步诊断为急性脑卒中。急诊电脑断层显示左晶状体核及左内囊后肢低密度病变。磁共振成像(MRI)显示左侧晶状体核、左侧内囊、左侧丘脑、左侧额顶叶室周区FLAIR病变高,部分区域弥散受限,增强不均匀。病变的MR谱显示胆碱峰升高,肌酸和NAA峰降低,最大胆碱/肌酸比2.25。她的症状恶化为进行性头痛和运动性失语。后续MRI显示病变沿左额叶活检道呈不均匀强化延伸,增强和MR谱模式与病变相似。开颅切除左额叶病变包括肿块并行活检道。病变表现为急性和慢性炎症细胞浸润,伴巨噬细胞、坏死组织和反应性胶质细胞增生。进一步的病理检查显示脱髓鞘灶与相对轴突保存,大量CD68+巨噬细胞与胞浆内Luxol快蓝(+)髓磷脂碎片。血管周围和实质的CD3+ t细胞被发现,特别是脱髓鞘灶。这些发现支持肿瘤性多发性硬化症的诊断。经甲泼尼龙脉冲治疗和静脉注射免疫球蛋白(IVIG)治疗后病情好转。治疗后4个月的MRI随访显示先前存在的不均匀强化病变几乎消失。
{"title":"Tumefactive Multiple Sclerosis Clinically Mimicking Acute Stroke and Lesional Migration Along the Biopsy Tract: A Case Report","authors":"O. Tritanon, Arunee Singhsnaeh, Jiraporn Laothamatus, A. Boongird, D. Ratanakorn, P. Nitiyanant","doi":"10.46475/aseanjr.v19i2.33","DOIUrl":"https://doi.org/10.46475/aseanjr.v19i2.33","url":null,"abstract":"Tumefactive multiple sclerosis is a form of demyelinating disease which patient can present with acute stroke. We reported a case of a 49-year-old woman with well controlled hypertension, who presented with right hemiplegia 15 hours prior to admission. The initial diagnosis of acute stroke was made. Emergency computed tomography showed hypodense lesion at the left lentiform nucleus and posterior limb of the left internal capsule. The magnetic resonance imaging (MRI) study showed hyperintense FLAIR lesion in the left lentiform nucleus, left internal capsule, left thalamus, and periventricular area of the left frontoparietal region, some areas of restricted diffusion and inhomogeneous enhancement. The MR spectroscopy (MRS) of the lesion showed increased choline peak, decreased creatine and NAA peaks, and maximal choline to creatine ratio 2.25. Her symptoms deteriorated with progressive headache and motor aphasia. The follow up MRI showed extension of the inhomogeneous enhancing lesion along the biopsy tract at the left frontal lobe with the enhancing and MR spectra pattern similar to the lesion. The craniotomy with left frontal lesion excision included the mass and the biopsy tract was done. The lesion showed acute and chronic inflammatory cell infiltration with macrophages, necrotic tissue and reactive gliosis. The further pathological worked up demonstrated foci of demyelination with relative axonal preservation, numerous CD68+ macrophages with intracyto-plasmic Luxol fast blue(+) myelin debris. Perivascular and parenchymal CD3+ T-cells were identified, especially in demyelinating foci. These findings supported the diagnosis of tumefactive multiple sclerosis. Her conditions were improved after treating with pulse methylprednisolone and intravenous immunoglobulin (IVIG). Follow up MRI study 4 months after treatment revealed almost resolution of the preexisting inhomogeneous enhancing lesion.","PeriodicalId":180936,"journal":{"name":"The ASEAN Journal of Radiology","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124708891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kinked coronary saphenous vein graft after aortic dissection surgery: An unusual differential diagnosis of cardiac tamponade 主动脉夹层术后冠状隐静脉移植物扭结:心脏填塞的一种不寻常的鉴别诊断
Pub Date : 1900-01-01 DOI: 10.46475/aseanjr.v22i2.118
K. Rathore, M. Teh, M. Newman
A 73-year-old female patient presented with cardiac tamponade following Stanford type A aortic dissection required immediate pericardiocentesis and followed by root replacement with coronary artery bypass grafting. The patient's postoperative course was eventful and coronary graft kinking contributed to myocardial ischemia, but the presentation was confused with cardiac tamponade.
一位73岁的女性患者在斯坦福A型主动脉夹层后出现心脏填塞,需要立即进行心包穿刺,随后进行冠状动脉旁路移植术。患者的术后过程是不稳定的,冠状动脉移植物扭结导致心肌缺血,但表现与心脏填塞混淆。
{"title":"Kinked coronary saphenous vein graft after aortic dissection surgery: An unusual differential diagnosis of cardiac tamponade","authors":"K. Rathore, M. Teh, M. Newman","doi":"10.46475/aseanjr.v22i2.118","DOIUrl":"https://doi.org/10.46475/aseanjr.v22i2.118","url":null,"abstract":"A 73-year-old female patient presented with cardiac tamponade following Stanford type A aortic dissection required immediate pericardiocentesis and followed by root replacement with coronary artery bypass grafting. The patient's postoperative course was eventful and coronary graft kinking contributed to myocardial ischemia, but the presentation was confused with cardiac tamponade.","PeriodicalId":180936,"journal":{"name":"The ASEAN Journal of Radiology","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122988929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utility of screening chest radiographs in patients with asymptomatic and mildly symptomatic COVID-19 at a field hospital in Samut Sakhon, Thailand 泰国Samut Sakhon一家野战医院胸部x线片筛查在无症状和轻度症状COVID-19患者中的应用
Pub Date : 1900-01-01 DOI: 10.46475/aseanjr.v22i2.119
Pilawan Trimankha, Lakkana Lakkana Jirapong, Runnaya Rungsin, Orawan Autravisittikul, P. Deesuwan, Yasinee Mekavuthikul, Anocha Chodpanich
Background: In a new episode of the COVID -19 pandemic in Thailand during the beginning of 2021, cases in Samut Sakhon Province mainly occurred in foreign workers and were mostly asymptomatic or had mild disease. To prevent overwhelming the local hospital, a field hospital was established which used chest radiography as one of screening tools for triaging patients.Objective: To determine the clinical utility of chest radiographs as a screening tool for COVID-19 patients who were asymptomatic or mildly symptomatic.Materials and Methods: Six hundred nineteen patients with COVID -19 (confirmed by reverse transcriptase-polymerase chain reaction) were registered at the field hospital at Samut Sakhon provincial sport stadium during 5-8 January 2021 and had chest radiographs taken. The image readings were based on the consensus of two radiologists and a final decision was made by a third radiologist if the first two did not agree. Findings on chest radiographs and clinical outcomes were evaluated.Results: The study included 619 radiographs; 328/619 (53%) men and 291/619 (47%) women had a mean age of 33.3+/- 9.7 (range, 5-64) years. There was mild disease in 13/619, and asymptomatic infections in 606/619.  Chest radiographs were normal in 568 (91.7%) and abnormal in 51 (8.3%) patients; typical findings of COVID-19 were seen in 3 (0.5%) patients. Other abnormal findings were found in 23 (3.8%) patients such as active tuberculosis in 6 (1.0%). Four patients were transferred to the hospital, one of whom required supplemental oxygen. Conclusion: Combined chest radiographic and clinical information allows better decisions regarding hospital transfers of asymptomatic and mildly symptomatic COVID-19 patients at a field hospital.
背景:在2021年初泰国发生的新一期COVID -19大流行中,萨穆特府的病例主要发生在外籍工人中,大多数无症状或病情轻微。为了防止当地医院不堪重负,建立了一所野战医院,使用胸部x线摄影作为筛选病人的工具之一。目的:探讨胸片作为筛查新冠肺炎无症状或轻度症状患者的临床应用价值。材料与方法:于2021年1月5日至8日在Samut Sakhon省体育场野战地医院登记了619例COVID -19患者(经逆转录-聚合酶链反应确诊),并拍摄了胸片。图像读数是基于两名放射科医生的共识,如果前两名放射科医生不同意,则由第三名放射科医生做出最终决定。评估胸片检查结果和临床结果。结果:纳入619张x线片;328/619(53%)男性和291/619(47%)女性的平均年龄为33.3±9.7岁(范围5-64岁)。619例中有13例为轻症,606例为无症状感染。胸片正常568例(91.7%),异常51例(8.3%);3例(0.5%)出现典型新冠肺炎表现。其他异常23例(3.8%),如活动性肺结核6例(1.0%)。四名病人被送往医院,其中一人需要补充氧气。结论:综合胸片和临床信息可以更好地决定野战医院对无症状和轻度症状的COVID-19患者的转院。
{"title":"Utility of screening chest radiographs in patients with asymptomatic and mildly symptomatic COVID-19 at a field hospital in Samut Sakhon, Thailand","authors":"Pilawan Trimankha, Lakkana Lakkana Jirapong, Runnaya Rungsin, Orawan Autravisittikul, P. Deesuwan, Yasinee Mekavuthikul, Anocha Chodpanich","doi":"10.46475/aseanjr.v22i2.119","DOIUrl":"https://doi.org/10.46475/aseanjr.v22i2.119","url":null,"abstract":"Background: In a new episode of the COVID -19 pandemic in Thailand during the beginning of 2021, cases in Samut Sakhon Province mainly occurred in foreign workers and were mostly asymptomatic or had mild disease. To prevent overwhelming the local hospital, a field hospital was established which used chest radiography as one of screening tools for triaging patients.\u0000Objective: To determine the clinical utility of chest radiographs as a screening tool for COVID-19 patients who were asymptomatic or mildly symptomatic.\u0000Materials and Methods: Six hundred nineteen patients with COVID -19 (confirmed by reverse transcriptase-polymerase chain reaction) were registered at the field hospital at Samut Sakhon provincial sport stadium during 5-8 January 2021 and had chest radiographs taken. The image readings were based on the consensus of two radiologists and a final decision was made by a third radiologist if the first two did not agree. Findings on chest radiographs and clinical outcomes were evaluated.\u0000Results: The study included 619 radiographs; 328/619 (53%) men and 291/619 (47%) women had a mean age of 33.3+/- 9.7 (range, 5-64) years. There was mild disease in 13/619, and asymptomatic infections in 606/619.  Chest radiographs were normal in 568 (91.7%) and abnormal in 51 (8.3%) patients; typical findings of COVID-19 were seen in 3 (0.5%) patients. Other abnormal findings were found in 23 (3.8%) patients such as active tuberculosis in 6 (1.0%). Four patients were transferred to the hospital, one of whom required supplemental oxygen. \u0000Conclusion: Combined chest radiographic and clinical information allows better decisions regarding hospital transfers of asymptomatic and mildly symptomatic COVID-19 patients at a field hospital.","PeriodicalId":180936,"journal":{"name":"The ASEAN Journal of Radiology","volume":"149 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124160728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two Case Reports of Madelungûs Disease: CT Finding. madelung<s:1>病2例CT表现。
Pub Date : 1900-01-01 DOI: 10.46475/aseanjr.v19i2.29
Chanpen Buranachokpaisan
Madelungûs disease or Benign symmetric lipomatosis is the rare disease that is the one of differential diagnosis of palpable neck mass that easily diagnosis by CT imaging. We report two cases of this condition and review the radiological findings.
马德隆氏病或良性对称脂肪瘤病是一种罕见的疾病,是可触及颈部肿块的鉴别诊断之一,CT成像容易诊断。我们报告两例此病并回顾其影像学表现。
{"title":"Two Case Reports of Madelungûs Disease: CT Finding.","authors":"Chanpen Buranachokpaisan","doi":"10.46475/aseanjr.v19i2.29","DOIUrl":"https://doi.org/10.46475/aseanjr.v19i2.29","url":null,"abstract":"Madelungûs disease or Benign symmetric lipomatosis is the rare disease that is the one of differential diagnosis of palpable neck mass that easily diagnosis by CT imaging. We report two cases of this condition and review the radiological findings.","PeriodicalId":180936,"journal":{"name":"The ASEAN Journal of Radiology","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126884643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
The ASEAN Journal of Radiology
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