Pub Date : 2023-04-23DOI: 10.26800/lv-145-supl2-cr04
{"title":"Ovarian thecoma in adolescent – a rare case of hirsutism","authors":"","doi":"10.26800/lv-145-supl2-cr04","DOIUrl":"https://doi.org/10.26800/lv-145-supl2-cr04","url":null,"abstract":"","PeriodicalId":18134,"journal":{"name":"Lijecnicki vjesnik","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48858795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-23DOI: 10.26800/lv-145-supl2-cm11
{"title":"Original research - COVID 19 pandemic impact on newly discovered cancer in family medicine practice: a five-year compariso","authors":"","doi":"10.26800/lv-145-supl2-cm11","DOIUrl":"https://doi.org/10.26800/lv-145-supl2-cm11","url":null,"abstract":"","PeriodicalId":18134,"journal":{"name":"Lijecnicki vjesnik","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69136337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-23DOI: 10.26800/lv-145-supl2-cr07
{"title":"Breaking the Boundaries: A Case of Humerus Reconstruction using a Fibula Autograft","authors":"","doi":"10.26800/lv-145-supl2-cr07","DOIUrl":"https://doi.org/10.26800/lv-145-supl2-cr07","url":null,"abstract":"","PeriodicalId":18134,"journal":{"name":"Lijecnicki vjesnik","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69136357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-23DOI: 10.26800/lv-145-supl2-cr16
{"title":"Arthritis as a presentation of paraneoplastic syndrome: A case report","authors":"","doi":"10.26800/lv-145-supl2-cr16","DOIUrl":"https://doi.org/10.26800/lv-145-supl2-cr16","url":null,"abstract":"","PeriodicalId":18134,"journal":{"name":"Lijecnicki vjesnik","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69136402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-23DOI: 10.26800/lv-145-supl2-cr62
{"title":"Personalized approach to patients with statin intolerance based on pharmacogenomics (function of OATP1B1 protein)","authors":"","doi":"10.26800/lv-145-supl2-cr62","DOIUrl":"https://doi.org/10.26800/lv-145-supl2-cr62","url":null,"abstract":"","PeriodicalId":18134,"journal":{"name":"Lijecnicki vjesnik","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69136500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-23DOI: 10.26800/lv-145-supl2-cr53
Lucija Vusić, Vedrana Verić, Matea Živko, Velimir, Altabás, Tea Kržak, Lorena Loje, I. Barić, D. Ninković
INTRODUCTION/OBJECTIVES: Cushing’s disease, a form of Cushing’s syndrome, is caused by excess ACTH production, a hormone that regulates cortisol production, by a benign tumor in the pituitary gland. As a result, cortisol levels are elevated, while ACTH levels are not suppressed due to autonomous secretion. The primary treatment option is surgery. Other therapeutic modalities include drug therapy, radiation, and bilateral adrenalectomy in selected cases. CASE PRESENTATION: In 2019, in a 65-year-old female patient with bilateral cortical adenoma, hypercortisolemia was detected. Further testing revealed elevated late-night salivary cortisol and insufficient cortisol suppression in Liddle’s test. ACTH was not suppressed. Initially, no pituitary tumor was detected on NMR scans. Fluconazole was used as her initial treatment to inhibit steroidogenesis, but without a proper response. Then the patient has been prescribed metyrapone. Three months after starting metyrapone, the patient began to experience side effects, including stomach pain and irregular blood pressure. After re-running pituitary tests, a microadenoma was found too small for surgery. Gamma knife radiosurgery was conducted, but one month postoperatively, cortisol levels remained high and cabergoline treatment was introduced without adequate response over time. In 2022, low– dose pasireotide eventually replaced cabergoline. The patient’s cortisol level is currently normal with clinical improvement and is being regularly checked. CONCLUSION: Cushing’s disease is a serious condition with systematic deteriorating effects. Treatment is still challenging, and there is still enough space for new treatment options that may benefit the patient. CR54 Management of metabolic crisis in three-dayold newborn Tea Kržaka, Lorena Lojea, Ivo Barićb, Dorotea Ninkovićb
简介/目的:库欣病是库欣综合征的一种，是由垂体良性肿瘤分泌过量的促肾上腺皮质激素(一种调节皮质醇分泌的激素)引起的。结果，皮质醇水平升高，而ACTH水平由于自主分泌而不受抑制。主要的治疗选择是手术。其他治疗方式包括药物治疗、放射治疗和部分病例的双侧肾上腺切除术。病例介绍:2019年，65岁女性双侧皮质腺瘤患者检测到高皮质血症。进一步的测试显示，Liddle试验显示，深夜唾液皮质醇升高，皮质醇抑制不足。ACTH未被抑制。最初，核磁共振扫描未检测到垂体瘤。氟康唑作为她的初始治疗，以抑制甾体生成，但没有适当的反应。然后给病人开了美替拉酮。在开始使用metyrapone三个月后，患者开始出现副作用，包括胃痛和不规则血压。在重新进行垂体检查后，发现微腺瘤太小，不适合手术。进行了伽玛刀放射治疗，但术后一个月，皮质醇水平仍然很高，卡麦角林治疗没有足够的反应。2022年，低剂量帕西肽最终取代了卡麦角林。患者的皮质醇水平目前正常，临床改善，正在定期检查。结论:库欣病是一种严重的系统性恶化疾病。治疗仍然具有挑战性，仍然有足够的空间来选择可能使患者受益的新治疗方案。CR54 3日龄新生儿代谢危机的管理Tea Kržaka, Lorena Lojea, Ivo Barićb, Dorotea Ninkovićb
{"title":"Management of Cushing’s disease when surgery is a tricky option – a case report","authors":"Lucija Vusić, Vedrana Verić, Matea Živko, Velimir, Altabás, Tea Kržak, Lorena Loje, I. Barić, D. Ninković","doi":"10.26800/lv-145-supl2-cr53","DOIUrl":"https://doi.org/10.26800/lv-145-supl2-cr53","url":null,"abstract":"INTRODUCTION/OBJECTIVES: Cushing’s disease, a form of Cushing’s syndrome, is caused by excess ACTH production, a hormone that regulates cortisol production, by a benign tumor in the pituitary gland. As a result, cortisol levels are elevated, while ACTH levels are not suppressed due to autonomous secretion. The primary treatment option is surgery. Other therapeutic modalities include drug therapy, radiation, and bilateral adrenalectomy in selected cases. CASE PRESENTATION: In 2019, in a 65-year-old female patient with bilateral cortical adenoma, hypercortisolemia was detected. Further testing revealed elevated late-night salivary cortisol and insufficient cortisol suppression in Liddle’s test. ACTH was not suppressed. Initially, no pituitary tumor was detected on NMR scans. Fluconazole was used as her initial treatment to inhibit steroidogenesis, but without a proper response. Then the patient has been prescribed metyrapone. Three months after starting metyrapone, the patient began to experience side effects, including stomach pain and irregular blood pressure. After re-running pituitary tests, a microadenoma was found too small for surgery. Gamma knife radiosurgery was conducted, but one month postoperatively, cortisol levels remained high and cabergoline treatment was introduced without adequate response over time. In 2022, low– dose pasireotide eventually replaced cabergoline. The patient’s cortisol level is currently normal with clinical improvement and is being regularly checked. CONCLUSION: Cushing’s disease is a serious condition with systematic deteriorating effects. Treatment is still challenging, and there is still enough space for new treatment options that may benefit the patient. CR54 Management of metabolic crisis in three-dayold newborn Tea Kržaka, Lorena Lojea, Ivo Barićb, Dorotea Ninkovićb","PeriodicalId":18134,"journal":{"name":"Lijecnicki vjesnik","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69136695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-23DOI: 10.26800/lv-145-supl2-cm05
{"title":"5 Correlating prostate imaging reporting and data system (PIRADS) version 2 scores with results of targeted biopsy of the prostate","authors":"","doi":"10.26800/lv-145-supl2-cm05","DOIUrl":"https://doi.org/10.26800/lv-145-supl2-cm05","url":null,"abstract":"","PeriodicalId":18134,"journal":{"name":"Lijecnicki vjesnik","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69136793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-23DOI: 10.26800/lv-145-supl2-cr76
{"title":"100 BLOOD TRANSFUSIONS IN 10 MONTHS DUE TO HEYDE SYNDROME","authors":"","doi":"10.26800/lv-145-supl2-cr76","DOIUrl":"https://doi.org/10.26800/lv-145-supl2-cr76","url":null,"abstract":"","PeriodicalId":18134,"journal":{"name":"Lijecnicki vjesnik","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69137140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：