Pub Date : 2023-07-01DOI: 10.1007/s11018-023-02219-4
V. Grigorievsky, Y. Tezadov
{"title":"Compensation for the Systematic Error of Spectral Measurements of the Background Concentration of Methane in the Earth's Atmosphere","authors":"V. Grigorievsky, Y. Tezadov","doi":"10.1007/s11018-023-02219-4","DOIUrl":"https://doi.org/10.1007/s11018-023-02219-4","url":null,"abstract":"","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"66 1","pages":"259 - 264"},"PeriodicalIF":0.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44086943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.1007/s11018-023-02221-w
O. G. Bondar, E. O. Brezhneva, A. Zubarev
{"title":"Improvement of Algorithms for Measuring Temperature with Two-Wire Connection of Resistance Thermometers","authors":"O. G. Bondar, E. O. Brezhneva, A. Zubarev","doi":"10.1007/s11018-023-02221-w","DOIUrl":"https://doi.org/10.1007/s11018-023-02221-w","url":null,"abstract":"","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"66 1","pages":"273 - 278"},"PeriodicalIF":0.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47830974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.1007/s11018-023-02222-9
P. Bazylev, V. Lugovoi
{"title":"Results of the COOMET 706/RU-A/16 Pilot Comparison of National Standards of the Unit of Propagation Velocity of Longitudinal Ultrasonic Waves in Solids","authors":"P. Bazylev, V. Lugovoi","doi":"10.1007/s11018-023-02222-9","DOIUrl":"https://doi.org/10.1007/s11018-023-02222-9","url":null,"abstract":"","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"66 1","pages":"279 - 287"},"PeriodicalIF":0.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52603540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.1007/s11018-023-02224-7
D. V. Golovin
{"title":"Correction to: Modulus of Complex Acoustic Impedance of Air in a Cylindrical Closed Volume: Calculation Using Numerical Simulation","authors":"D. V. Golovin","doi":"10.1007/s11018-023-02224-7","DOIUrl":"https://doi.org/10.1007/s11018-023-02224-7","url":null,"abstract":"","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"66 1","pages":"289 - 289"},"PeriodicalIF":0.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44738618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.1007/s11018-023-02220-x
V. Fateev, F. Smirnov, A. A. Karaush
{"title":"Method for Relative Syntonization of Quantum Clocks: Experimental Studies","authors":"V. Fateev, F. Smirnov, A. A. Karaush","doi":"10.1007/s11018-023-02220-x","DOIUrl":"https://doi.org/10.1007/s11018-023-02220-x","url":null,"abstract":"","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"66 1","pages":"265 - 272"},"PeriodicalIF":0.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46893023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Transarterial chemoembolization (TACE) is the standard treatment for unresectable intermediate-stage hepatocellular carcinoma (HCC), but recurrence after TACE is common. The present phase 2, prospective, multicenter, single-arm trial, the TACTICS-L trial, investigated the efficacy and safety of TACE plus lenvatinib (LEN), a drug that more strongly promotes vascular normalization and has a better objective response rate (ORR) than sorafenib (jRCTs031180074).
Methods: Participants were patients with HCC who had not previously received systemic therapy, hepatic arterial infusion chemotherapy, or immunotherapy and who were ineligible for resection or percutaneous ablation therapy. LEN was to be administered 14-21 days before the first TACE, stopped 2 days before TACE, and resumed 3 days after TACE. Key inclusion criteria were unresectable HCC, Child-Pugh A liver function, 0-2 prior TACE sessions, tumor size ≤10 cm, number of tumors ≤10, and ECOG performance status 0-1. Key exclusion criteria were vascular invasion and extrahepatic spread. The primary endpoint was progression-free survival (PFS) by RECICL, and secondary endpoints were time to untreatable progression, ORR, overall survival (OS), and safety.
Results: A total of 62 HCC patients were enrolled in this trial. The median age was 72 years, 77.4% of patients were men, and 95.2% had PS 0. The primary endpoint of median PFS was 28.0 months (90% confidence interval [CI] 25.1-31.0) after a minimum 24 months of follow-up. The secondary endpoint of median OS was not reached (90% CI 35.5 months-NR). LEN-TACE achieved a high response rate and high complete response (CR) rate (4 weeks after the first TACE: ORR 79.0%, CR rate 53.2%; best response: ORR 88.7%, CR rate 67.7%) by RECICL. Exploratory subgroup analyses showed that the characteristics of responders/nonresponders (ORR and CR rate) were similar and that LEN-TACE would be effective in all subgroups, including the population in whom TACE alone would be less likely to be curative (e.g., patients with the non-simple nodular type or a high tumor burden). The relative dose intensity of LEN before the first TACE was important for achieving higher CR rate/ORR by LEN-TACE. No new safety concerns were observed.
Conclusion: The results of this trial provide encouraging evidence, supporting the efficacy and favorable safety profile of LEN-TACE in patients who are ineligible for locoregional therapy.
{"title":"A Phase 2, Prospective, Multicenter, Single-Arm Trial of Transarterial Chemoembolization Therapy in Combination Strategy with Lenvatinib in Patients with Unresectable Intermediate-Stage Hepatocellular Carcinoma: TACTICS-L Trial.","authors":"Masatoshi Kudo, Kazuomi Ueshima, Issei Saeki, Toru Ishikawa, Yoshitaka Inaba, Naoki Morimoto, Hiroshi Aikata, Nobukazu Tanabe, Yoshiyuki Wada, Yasuteru Kondo, Masahiro Tsuda, Kazuhiko Nakao, Takanori Ito, Tetsuya Hosaka, Yusuke Kawamura, Teiji Kuzuya, Shunsuke Nojiri, Chikara Ogawa, Hironori Koga, Keisuke Hino, Masafumi Ikeda, Michihisa Moriguchi, Takashi Hisai, Kenichi Yoshimura, Junji Furuse, Yasuaki Arai","doi":"10.1159/000531377","DOIUrl":"10.1159/000531377","url":null,"abstract":"<p><strong>Introduction: </strong>Transarterial chemoembolization (TACE) is the standard treatment for unresectable intermediate-stage hepatocellular carcinoma (HCC), but recurrence after TACE is common. The present phase 2, prospective, multicenter, single-arm trial, the TACTICS-L trial, investigated the efficacy and safety of TACE plus lenvatinib (LEN), a drug that more strongly promotes vascular normalization and has a better objective response rate (ORR) than sorafenib (jRCTs031180074).</p><p><strong>Methods: </strong>Participants were patients with HCC who had not previously received systemic therapy, hepatic arterial infusion chemotherapy, or immunotherapy and who were ineligible for resection or percutaneous ablation therapy. LEN was to be administered 14-21 days before the first TACE, stopped 2 days before TACE, and resumed 3 days after TACE. Key inclusion criteria were unresectable HCC, Child-Pugh A liver function, 0-2 prior TACE sessions, tumor size ≤10 cm, number of tumors ≤10, and ECOG performance status 0-1. Key exclusion criteria were vascular invasion and extrahepatic spread. The primary endpoint was progression-free survival (PFS) by RECICL, and secondary endpoints were time to untreatable progression, ORR, overall survival (OS), and safety.</p><p><strong>Results: </strong>A total of 62 HCC patients were enrolled in this trial. The median age was 72 years, 77.4% of patients were men, and 95.2% had PS 0. The primary endpoint of median PFS was 28.0 months (90% confidence interval [CI] 25.1-31.0) after a minimum 24 months of follow-up. The secondary endpoint of median OS was not reached (90% CI 35.5 months-NR). LEN-TACE achieved a high response rate and high complete response (CR) rate (4 weeks after the first TACE: ORR 79.0%, CR rate 53.2%; best response: ORR 88.7%, CR rate 67.7%) by RECICL. Exploratory subgroup analyses showed that the characteristics of responders/nonresponders (ORR and CR rate) were similar and that LEN-TACE would be effective in all subgroups, including the population in whom TACE alone would be less likely to be curative (e.g., patients with the non-simple nodular type or a high tumor burden). The relative dose intensity of LEN before the first TACE was important for achieving higher CR rate/ORR by LEN-TACE. No new safety concerns were observed.</p><p><strong>Conclusion: </strong>The results of this trial provide encouraging evidence, supporting the efficacy and favorable safety profile of LEN-TACE in patients who are ineligible for locoregional therapy.</p>","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"14 1","pages":"99-112"},"PeriodicalIF":13.8,"publicationDate":"2023-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10857829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73003357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.1007/s11018-023-02202-z
A. A. Petukhov, B. G. Potapov, V. Kytin, M. Y. Ghavalyan, L. V. Yurov, E. Aslanyan, A. Shchipunov
{"title":"Get 79-2020 State Primary Special Standard of the Unit of Specific Heat of Solids in the Temperature Range from 2 to 300 K","authors":"A. A. Petukhov, B. G. Potapov, V. Kytin, M. Y. Ghavalyan, L. V. Yurov, E. Aslanyan, A. Shchipunov","doi":"10.1007/s11018-023-02202-z","DOIUrl":"https://doi.org/10.1007/s11018-023-02202-z","url":null,"abstract":"","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"66 1","pages":"143 - 148"},"PeriodicalIF":0.5,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47319294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.1007/s11018-023-02203-y
S. F. Levin
{"title":"Cosmological Distances Scale. Part 15: Cosmic Jerk and Gravitational Dipole of Inhomogeneity","authors":"S. F. Levin","doi":"10.1007/s11018-023-02203-y","DOIUrl":"https://doi.org/10.1007/s11018-023-02203-y","url":null,"abstract":"","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"66 1","pages":"149 - 154"},"PeriodicalIF":0.5,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47522574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.1007/s11018-023-02207-8
A. Sahakyan, A. A. Yushina, A. Levin
{"title":"Classification of Brandy and Cognac Production by Geographical Origin and Aging Using Raman Scattering and Machine Learning","authors":"A. Sahakyan, A. A. Yushina, A. Levin","doi":"10.1007/s11018-023-02207-8","DOIUrl":"https://doi.org/10.1007/s11018-023-02207-8","url":null,"abstract":"","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"66 1","pages":"173 - 178"},"PeriodicalIF":0.5,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48943925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.1007/s11018-023-02209-6
A. Sandulyak, D. A. Sandulyak, Y. Gorpinenko, A. Sandulyak, V. Ershova, I. A. Solovev
{"title":"Magnetic Properties of Tube-Layers of Magnetized Chains of Spheres: Monitoring by Measured Magnetic Core Parameters","authors":"A. Sandulyak, D. A. Sandulyak, Y. Gorpinenko, A. Sandulyak, V. Ershova, I. A. Solovev","doi":"10.1007/s11018-023-02209-6","DOIUrl":"https://doi.org/10.1007/s11018-023-02209-6","url":null,"abstract":"","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"66 1","pages":"191 - 196"},"PeriodicalIF":0.5,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42434012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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