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Association of ABO blood groups and Diabetes Mellitus in King Abdulaziz University Hospital: A case-control study 阿卜杜勒阿齐兹国王大学医院ABO血型与糖尿病的关系:一项病例对照研究
Pub Date : 2023-08-09 DOI: 10.54905/disssi/v27i138/e330ms3145
Mohammed A Jan, Obadah S Mishiming, Abdulaziz G Aljohani, Ayar A Bukhari, Jalal M Al-Sayyad, Sohaib E Althagafi, Aseel Ahmed N Althagafi, Khaled A Yaghmour
Background: Diabetes mellitus (DM) is a metabolic disorder resulting from decreased insulin production or increased cell resistance to insulin. The association between DM risk and 'ABO' blood groups have demonstrated by a few earlier kinds of research in the Jeddah region. In this study, we aimed to assess the relationship between ABO blood groups and DM at King Abdulaziz University Hospital (KAUH), Jeddah, Saudi Arabia. Methodology: The Institutional Review Board (IRB) at KAUH, Jeddah, Saudi Arabia, approved this proposal. The cases were taken from the database of patients diagnosed with Type 1 diabetes mellitus (T1D) or Type 2 diabetes mellitus (T2D), and controls were chosen randomly from family medicine clinics that came for routine checkups. Demographics, comorbidities, and lab values were collected and analyzed. Results: This study included 718 samples; 396 were females, 322 were males, the mean age was 42.55±11.22, 51.1% were diabetic, and the majority of them had T1D (52%). The most common comorbidities were hypertension (56.9%) and ischemic heart disease (IHD) (24.3%). Patients with T2D were more prone to develop comorbidities than patients with T1D (77.8% vs. 62.8%, p=0.03). Patients whose blood group was O-had a higher rate of IHD than the rest of the blood groups (p=0.02). No significant association was found between ABO blood groups and HbA1c. Conclusion: Blood group O is the most prevalent and is associated with developing IHD among people with diabetes. Hypertension was found to be the most common comorbidity, followed by IHD and heart failure.
{"title":"Association of ABO blood groups and Diabetes Mellitus in King Abdulaziz University Hospital: A case-control study","authors":"Mohammed A Jan, Obadah S Mishiming, Abdulaziz G Aljohani, Ayar A Bukhari, Jalal M Al-Sayyad, Sohaib E Althagafi, Aseel Ahmed N Althagafi, Khaled A Yaghmour","doi":"10.54905/disssi/v27i138/e330ms3145","DOIUrl":"https://doi.org/10.54905/disssi/v27i138/e330ms3145","url":null,"abstract":"Background: Diabetes mellitus (DM) is a metabolic disorder resulting from decreased insulin production or increased cell resistance to insulin. The association between DM risk and 'ABO' blood groups have demonstrated by a few earlier kinds of research in the Jeddah region. In this study, we aimed to assess the relationship between ABO blood groups and DM at King Abdulaziz University Hospital (KAUH), Jeddah, Saudi Arabia. Methodology: The Institutional Review Board (IRB) at KAUH, Jeddah, Saudi Arabia, approved this proposal. The cases were taken from the database of patients diagnosed with Type 1 diabetes mellitus (T1D) or Type 2 diabetes mellitus (T2D), and controls were chosen randomly from family medicine clinics that came for routine checkups. Demographics, comorbidities, and lab values were collected and analyzed. Results: This study included 718 samples; 396 were females, 322 were males, the mean age was 42.55±11.22, 51.1% were diabetic, and the majority of them had T1D (52%). The most common comorbidities were hypertension (56.9%) and ischemic heart disease (IHD) (24.3%). Patients with T2D were more prone to develop comorbidities than patients with T1D (77.8% vs. 62.8%, p=0.03). Patients whose blood group was O-had a higher rate of IHD than the rest of the blood groups (p=0.02). No significant association was found between ABO blood groups and HbA1c. Conclusion: Blood group O is the most prevalent and is associated with developing IHD among people with diabetes. Hypertension was found to be the most common comorbidity, followed by IHD and heart failure.","PeriodicalId":18393,"journal":{"name":"Medical Science","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135745932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Public perception of common Ear, Nose, and Throat-related diseases in the Makkah region of Saudi Arabia: A cross-sectional study 沙特阿拉伯麦加地区公众对常见耳鼻喉相关疾病的看法:一项横断面研究
Pub Date : 2023-08-09 DOI: 10.54905/disssi/v27i138/e341ms3182
Saad M Alharthi, Sanad M Alharthi, Faisal M Alzahrani, Abdulrahman F Kabli, Abdulrahman Baabdullah, Bashaer A Alharbi, Hulayyil H Almuqati, Mohammed S Almasoudi, Bayan O Babtain, Ameera A Alhawsawi, Shrooq M Almasudi, Fatimah A Alzubaidi, Mokhtar Shatla
Background: Ear, nose, and throat (ENT)-related complaints are among the most frequent medical issues worldwide. Our objective was to evaluate the awareness level of, and attitudes toward, ENT-related diseases among residents of the Makkah region of Saudi Arabia. Methodology: A cross-sectional study was conducted in June 2023 by posting an online survey in Arabic on various social media platforms. The survey contained 23 questions to determine the participants' general knowledge about frequent ENT-related issues. Results: The study involved 420 participants. Most participants (82.1%) had poor knowledge about ENT-related issues (score <50%). Regarding general knowledge, 64.0% of participants properly answered the safety of using cotton buds, and 35.2% correctly answered the question related to respiratory viral infections and antibiotic use. A minority of participants, 14.8% and 11.4%, correctly answered questions about the role of vitamin C in the prevention and treatment of the common cold and the difference between vertigo and dizziness, respectively. Most individuals had an acceptable level of knowledge regarding ear and hearing issues (score ≥50%). The most correctly answered question was the one related to smoking and laryngeal cancer (90.5%). The most commonly used information sources were society, websites, and ENT clinics. Conclusion: According to this study, poor knowledge about ENT-related complaints is frequent among individuals in the Makkah region. Furthermore, our results suggest increasing awareness and educating the community through community campaigns and awareness programs because the community was the main source of information for survey participants.
{"title":"Public perception of common Ear, Nose, and Throat-related diseases in the Makkah region of Saudi Arabia: A cross-sectional study","authors":"Saad M Alharthi, Sanad M Alharthi, Faisal M Alzahrani, Abdulrahman F Kabli, Abdulrahman Baabdullah, Bashaer A Alharbi, Hulayyil H Almuqati, Mohammed S Almasoudi, Bayan O Babtain, Ameera A Alhawsawi, Shrooq M Almasudi, Fatimah A Alzubaidi, Mokhtar Shatla","doi":"10.54905/disssi/v27i138/e341ms3182","DOIUrl":"https://doi.org/10.54905/disssi/v27i138/e341ms3182","url":null,"abstract":"Background: Ear, nose, and throat (ENT)-related complaints are among the most frequent medical issues worldwide. Our objective was to evaluate the awareness level of, and attitudes toward, ENT-related diseases among residents of the Makkah region of Saudi Arabia. Methodology: A cross-sectional study was conducted in June 2023 by posting an online survey in Arabic on various social media platforms. The survey contained 23 questions to determine the participants' general knowledge about frequent ENT-related issues. Results: The study involved 420 participants. Most participants (82.1%) had poor knowledge about ENT-related issues (score <50%). Regarding general knowledge, 64.0% of participants properly answered the safety of using cotton buds, and 35.2% correctly answered the question related to respiratory viral infections and antibiotic use. A minority of participants, 14.8% and 11.4%, correctly answered questions about the role of vitamin C in the prevention and treatment of the common cold and the difference between vertigo and dizziness, respectively. Most individuals had an acceptable level of knowledge regarding ear and hearing issues (score ≥50%). The most correctly answered question was the one related to smoking and laryngeal cancer (90.5%). The most commonly used information sources were society, websites, and ENT clinics. Conclusion: According to this study, poor knowledge about ENT-related complaints is frequent among individuals in the Makkah region. Furthermore, our results suggest increasing awareness and educating the community through community campaigns and awareness programs because the community was the main source of information for survey participants.","PeriodicalId":18393,"journal":{"name":"Medical Science","volume":"121 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135745925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcome of neonates born to mother with pregnancy induced hypertension: A clinical study 妊娠高血压母亲所生新生儿结局的临床研究
Pub Date : 2023-08-09 DOI: 10.54905/disssi/v27i138/e335ms2863
Apoorv Jain, Amar Taksande
Introduction: Eclampsia as well as associated complications can be evaded with proper antenatal care, early recognition of pre-eclampsia, and early intervention. Thus, the present study was undertaken to compare outcome of neonates born to mothers with pre-eclampsia, eclampsia and gestational hypertension. Materials and Method: The present study was conducted among neonates born to a mother with PIH. Outcome of the neonate who satisfied the inclusion criteria was documented. Qualitative data was analysed using Chi square test and Fischer’s exact test. Differences between means were compared by unpaired student’s t -test. P value less than 0.05 is considered as level of significance. Results: 33% were born to mothers with gestational hypertension, 60% were born to mothers with pre-eclampsia and 7% were born to mothers with eclampsia 9% neonates required resuscitation at birth and 91% neonates did not require any resuscitation. 32.5% were born to mother with gestational hypertension of which 87.18% were discharged, 6.41% were IUD, 3.8% died, 60.4% were delivered by mothers with pre-eclampsia of which 97.6% were discharged, 2.3% were IUD, 6.9% were born to mothers with eclampsia, out of which 66.6% were discharged and 11.1% were IUD, 22.2% died. There is statistically significant association between type of PIH and outcome. Conclusion: The placental alterations along with various fetal are associated with pregnancy-induced hypertension. Hence, it is pivotal to closely scrutinise these infants as a primary measure to decrease morbidity. Therefore, as a preventive method and detect pre-eclampsia, it is crucial to provide appropriate antenatal care to all pregnant women.
{"title":"Outcome of neonates born to mother with pregnancy induced hypertension: A clinical study","authors":"Apoorv Jain, Amar Taksande","doi":"10.54905/disssi/v27i138/e335ms2863","DOIUrl":"https://doi.org/10.54905/disssi/v27i138/e335ms2863","url":null,"abstract":"Introduction: Eclampsia as well as associated complications can be evaded with proper antenatal care, early recognition of pre-eclampsia, and early intervention. Thus, the present study was undertaken to compare outcome of neonates born to mothers with pre-eclampsia, eclampsia and gestational hypertension. Materials and Method: The present study was conducted among neonates born to a mother with PIH. Outcome of the neonate who satisfied the inclusion criteria was documented. Qualitative data was analysed using Chi square test and Fischer’s exact test. Differences between means were compared by unpaired student’s t -test. P value less than 0.05 is considered as level of significance. Results: 33% were born to mothers with gestational hypertension, 60% were born to mothers with pre-eclampsia and 7% were born to mothers with eclampsia 9% neonates required resuscitation at birth and 91% neonates did not require any resuscitation. 32.5% were born to mother with gestational hypertension of which 87.18% were discharged, 6.41% were IUD, 3.8% died, 60.4% were delivered by mothers with pre-eclampsia of which 97.6% were discharged, 2.3% were IUD, 6.9% were born to mothers with eclampsia, out of which 66.6% were discharged and 11.1% were IUD, 22.2% died. There is statistically significant association between type of PIH and outcome. Conclusion: The placental alterations along with various fetal are associated with pregnancy-induced hypertension. Hence, it is pivotal to closely scrutinise these infants as a primary measure to decrease morbidity. Therefore, as a preventive method and detect pre-eclampsia, it is crucial to provide appropriate antenatal care to all pregnant women.","PeriodicalId":18393,"journal":{"name":"Medical Science","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135745927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prostate cancer severity prediction in advanced age groups in low incidence region 低发病率地区高龄人群前列腺癌严重程度预测
Pub Date : 2023-08-09 DOI: 10.54905/disssi/v27i138/e331ms3168
Mostafa A Arafa, Karim H Farhat, Danny M Rabah, Alaa Mokhtar, Waleed Al-Taweel, Alanoud Abdullah Albukairi, Mohamed Fawzi Farahat, Horeya M Ismail
Objectives: To explore the relationship between prostate cancer (PCa) aggressiveness and the advanced age at diagnosis. Materials and methods: Men who had high Prostate-specific antigen (PSA) (>4ng/ml) were referred to the urology clinic for further evaluation by MRI, and those with positive findings were scheduled for a biopsy. Depending on its size, a systematic 12-core procedure was employed in each patient, following the extraction of 2-6 cores from the identified lesion. Non-significant prostate cancer had a Gleason score (GS) lower than 3 + 4, whereas significant PCa was categorized as having a GS of 3 + 4 or higher. Results: Out of all screened 6482 cases, 75 were diagnosed as clinically significant cancer (CSC) cases, and 21 were non-clinically significant. Age was significantly correlated with CSC in univariate analysis, where the percentage of CSC cases increased with increased age categories, and it was a significant independent predictor in all multivariate models. Its discriminative ability is high (AUC=0.75). The percentage of CSC cases (63.6%) is significantly higher in the smallest volume category (≤33 cc) in comparison to the 34-60 cc category (29.5%) and >60 cc category (31.8%). The interaction parameter, age-prostate volume, was a significant independent predictor of CSC, particularly for the smaller prostate volume (<33 cc). Conclusions: Age is considered a significant independent predictor of CSC, in general, and for older men in specific. The ability of prostate size to detect CSC becomes higher when interacting with age, particularly for small prostate size.
{"title":"Prostate cancer severity prediction in advanced age groups in low incidence region","authors":"Mostafa A Arafa, Karim H Farhat, Danny M Rabah, Alaa Mokhtar, Waleed Al-Taweel, Alanoud Abdullah Albukairi, Mohamed Fawzi Farahat, Horeya M Ismail","doi":"10.54905/disssi/v27i138/e331ms3168","DOIUrl":"https://doi.org/10.54905/disssi/v27i138/e331ms3168","url":null,"abstract":"Objectives: To explore the relationship between prostate cancer (PCa) aggressiveness and the advanced age at diagnosis. Materials and methods: Men who had high Prostate-specific antigen (PSA) (>4ng/ml) were referred to the urology clinic for further evaluation by MRI, and those with positive findings were scheduled for a biopsy. Depending on its size, a systematic 12-core procedure was employed in each patient, following the extraction of 2-6 cores from the identified lesion. Non-significant prostate cancer had a Gleason score (GS) lower than 3 + 4, whereas significant PCa was categorized as having a GS of 3 + 4 or higher. Results: Out of all screened 6482 cases, 75 were diagnosed as clinically significant cancer (CSC) cases, and 21 were non-clinically significant. Age was significantly correlated with CSC in univariate analysis, where the percentage of CSC cases increased with increased age categories, and it was a significant independent predictor in all multivariate models. Its discriminative ability is high (AUC=0.75). The percentage of CSC cases (63.6%) is significantly higher in the smallest volume category (≤33 cc) in comparison to the 34-60 cc category (29.5%) and >60 cc category (31.8%). The interaction parameter, age-prostate volume, was a significant independent predictor of CSC, particularly for the smaller prostate volume (<33 cc). Conclusions: Age is considered a significant independent predictor of CSC, in general, and for older men in specific. The ability of prostate size to detect CSC becomes higher when interacting with age, particularly for small prostate size.","PeriodicalId":18393,"journal":{"name":"Medical Science","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135745930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality of life in patients who underwent bariatric surgery at a tertiary hospital in Madina, Saudi Arabia: A cross-sectional study 沙特阿拉伯麦地那一家三级医院接受减肥手术患者的生活质量:一项横断面研究
Pub Date : 2023-08-09 DOI: 10.54905/disssi/v27i138/e334ms3180
Nouf Abdulaziz Alkalbi, Sami Abdo Radman Al-Dubai, Abdulhamid Awadh Alharbi, Maha Mubarak Almutairi, Zahrah Ibrahim Alsharif, Masheal Abdullah Abdulmaqsud, Arwa Atiah Almalki, Zeidan Abdu Zeidan
Background: Body mass index and comorbidities determine surgical indications for bariatric surgery. The study aimed to evaluate health-related quality of life (QoL) in patients following laparoscopic sleeve gastrectomy to determine their perceptions of the surgical outcome and identify potential QoL-related factors. Patients and Methods: This cross-sectional study, conducted at King Fahad Hospital, Al-Madina, comprised 383 patients aged ≥18 years who had undergone bariatric surgery ≥3 months earlier. Sociodemographic and surgical complication data were collected using the Short Form Health Survey (SF-36)-QoL. Results: “Social functioning” had the highest mean (78.7 ± 19), followed by “role limitations due to physical health” and “pain” (76.8 ± 36.4 and 76.2 ± 25.3, respectively). One -third of the patients had diabetes mellitus, and two-thirds had hypertension. Older age, higher educational level, marriage, shorter post-operative period, and absence of complications were associated with higher scores in the “role limitations due to emotional issues” domain. Younger age, higher income, a more extended post-operative period, and being single were associated with higher scores in the “physical functioning” domain. Conclusion: Age, educational level, income, marital status, history of chronic disease, time since surgery, and complications were associated with QoL. Physical health functioning, emotional issues, energy/fatigue, and general health all had high QoL scores. Gastroesophageal reflux disease, gallbladder stones, and malnutrition were common complications post-operatively
{"title":"Quality of life in patients who underwent bariatric surgery at a tertiary hospital in Madina, Saudi Arabia: A cross-sectional study","authors":"Nouf Abdulaziz Alkalbi, Sami Abdo Radman Al-Dubai, Abdulhamid Awadh Alharbi, Maha Mubarak Almutairi, Zahrah Ibrahim Alsharif, Masheal Abdullah Abdulmaqsud, Arwa Atiah Almalki, Zeidan Abdu Zeidan","doi":"10.54905/disssi/v27i138/e334ms3180","DOIUrl":"https://doi.org/10.54905/disssi/v27i138/e334ms3180","url":null,"abstract":"Background: Body mass index and comorbidities determine surgical indications for bariatric surgery. The study aimed to evaluate health-related quality of life (QoL) in patients following laparoscopic sleeve gastrectomy to determine their perceptions of the surgical outcome and identify potential QoL-related factors. Patients and Methods: This cross-sectional study, conducted at King Fahad Hospital, Al-Madina, comprised 383 patients aged ≥18 years who had undergone bariatric surgery ≥3 months earlier. Sociodemographic and surgical complication data were collected using the Short Form Health Survey (SF-36)-QoL. Results: “Social functioning” had the highest mean (78.7 ± 19), followed by “role limitations due to physical health” and “pain” (76.8 ± 36.4 and 76.2 ± 25.3, respectively). One -third of the patients had diabetes mellitus, and two-thirds had hypertension. Older age, higher educational level, marriage, shorter post-operative period, and absence of complications were associated with higher scores in the “role limitations due to emotional issues” domain. Younger age, higher income, a more extended post-operative period, and being single were associated with higher scores in the “physical functioning” domain. Conclusion: Age, educational level, income, marital status, history of chronic disease, time since surgery, and complications were associated with QoL. Physical health functioning, emotional issues, energy/fatigue, and general health all had high QoL scores. Gastroesophageal reflux disease, gallbladder stones, and malnutrition were common complications post-operatively","PeriodicalId":18393,"journal":{"name":"Medical Science","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135745929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors of erectile dysfunction among type 2 diabetes mellitus patients: A retrospective real-world study in the Hospital Universiti Sains Malaysia 2型糖尿病患者勃起功能障碍的危险因素:马来西亚医院大学的一项回顾性真实世界研究
Pub Date : 2023-08-06 DOI: 10.54905/disssi/v27i138/e327ms3065
Wan Mohd Nazlee Wan Zainon, Mohd Albaihaqi Ahmad Lotopi, Nur Syuhada Roslan, Norazlina Mat Nawi, Arsalan Humayun, Mohamad Arif Awang Nawi
Introduction : Erectile dysfunction (ED) is a common complication in men with type 2 diabetes mellitus and can significantly impact their quality of life and relationships. However, the prevalence of erectile dysfunction is usually underestimated in developing countries due to social stigma, lack of awareness, limited access to healthcare, and underdiagnosis. This study aims to identify the risk factors associated with ED in type 2 male diabetics. Methodology: A retrospective study was conducted at the Hospital Universiti Sains Malaysia involving T2DM male patients who also experienced ED. The patient's medical records were reviewed to identify potential risk factors for ED by using Structural Equation Modelling (SEM), including direct and indirect effects. The best SEM model was identified based on goodness-of-fit measures. The models were created and analyzed using IBM SPSS Amos 20 software. Results : The results of our study showed that the final model had a good fit, and only three independent predictors, including old age, FBS, and TC, had a direct statistically significant effect on erectile dysfunction among T2DM patients in our study population. Other variables, such as BMI, HBA1C count, antidepressant status, and smoking status, did not significantly affect. The goodness of fit statistics, such as GFI, NFI, CFI, TLI, and RMSEA values, indicate a good model fit. Conclusion : Our findings suggest that early detection and management of these risk factors could help prevent or reduce the risk of ED in T2DM patients. Comprehensive care of T2DM patients is essential to prevent or reduce the risk of ED.
{"title":"Risk factors of erectile dysfunction among type 2 diabetes mellitus patients: A retrospective real-world study in the Hospital Universiti Sains Malaysia","authors":"Wan Mohd Nazlee Wan Zainon, Mohd Albaihaqi Ahmad Lotopi, Nur Syuhada Roslan, Norazlina Mat Nawi, Arsalan Humayun, Mohamad Arif Awang Nawi","doi":"10.54905/disssi/v27i138/e327ms3065","DOIUrl":"https://doi.org/10.54905/disssi/v27i138/e327ms3065","url":null,"abstract":"Introduction : Erectile dysfunction (ED) is a common complication in men with type 2 diabetes mellitus and can significantly impact their quality of life and relationships. However, the prevalence of erectile dysfunction is usually underestimated in developing countries due to social stigma, lack of awareness, limited access to healthcare, and underdiagnosis. This study aims to identify the risk factors associated with ED in type 2 male diabetics. Methodology: A retrospective study was conducted at the Hospital Universiti Sains Malaysia involving T2DM male patients who also experienced ED. The patient's medical records were reviewed to identify potential risk factors for ED by using Structural Equation Modelling (SEM), including direct and indirect effects. The best SEM model was identified based on goodness-of-fit measures. The models were created and analyzed using IBM SPSS Amos 20 software. Results : The results of our study showed that the final model had a good fit, and only three independent predictors, including old age, FBS, and TC, had a direct statistically significant effect on erectile dysfunction among T2DM patients in our study population. Other variables, such as BMI, HBA1C count, antidepressant status, and smoking status, did not significantly affect. The goodness of fit statistics, such as GFI, NFI, CFI, TLI, and RMSEA values, indicate a good model fit. Conclusion : Our findings suggest that early detection and management of these risk factors could help prevent or reduce the risk of ED in T2DM patients. Comprehensive care of T2DM patients is essential to prevent or reduce the risk of ED.","PeriodicalId":18393,"journal":{"name":"Medical Science","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136044024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge, attitude and practices of self-medication and rational drug use habits among medical students in Madinah city 麦地那市医学生自我药疗知识、态度和行为及合理用药习惯
Pub Date : 2023-08-03 DOI: 10.54905/disssi/v27i138/e320ms3052
Hala Gasim Elssied, Renad Alsaedi, Rawabi Alharbi, Rahaf Almughathawi, Lama Alraddadi, Amirah Alzughaibi
Background: Rational use of drugs require that patient receive medicine appropriate to their clinical needs in a dose that meets their own individual requirements for an adequate period at the lowest cost to them and their community. In the real world, prescribing patterns do not always conform to these ideals and what prevails instead is inappropriate, irrational prescribing. Aims: This study aims to estimate the prevalence of self-medication practices and rational drug use among undergraduate University students in Madinah city, in order to update the information in this region. Methods: The study adopted a cross sectional study conducted on undergraduate medical students, as the sample size calculated using the Epi Info program accordingly the study population was (357) students in Madinah city in a period from (September 2022 to September 2023). A questionnaire was passed on digitally. Results: The practices of the participants towards experience any side effects while taking medication (28.9%) abandon the medication, while (28.2%) consult to physician, (19.6%) consult to the pharmacist, (13.2%) discontinue the course of the medication and start a new one with the same affect, (6.2%) consult to the family, 3.9% do nothing. Conclusions: The understanding, perspective, and behaviors of self-medication and drugs among medical students are substantially low with increasing use of self-prescribed medications, and antibiotics.
{"title":"Knowledge, attitude and practices of self-medication and rational drug use habits among medical students in Madinah city","authors":"Hala Gasim Elssied, Renad Alsaedi, Rawabi Alharbi, Rahaf Almughathawi, Lama Alraddadi, Amirah Alzughaibi","doi":"10.54905/disssi/v27i138/e320ms3052","DOIUrl":"https://doi.org/10.54905/disssi/v27i138/e320ms3052","url":null,"abstract":"Background: Rational use of drugs require that patient receive medicine appropriate to their clinical needs in a dose that meets their own individual requirements for an adequate period at the lowest cost to them and their community. In the real world, prescribing patterns do not always conform to these ideals and what prevails instead is inappropriate, irrational prescribing. Aims: This study aims to estimate the prevalence of self-medication practices and rational drug use among undergraduate University students in Madinah city, in order to update the information in this region. Methods: The study adopted a cross sectional study conducted on undergraduate medical students, as the sample size calculated using the Epi Info program accordingly the study population was (357) students in Madinah city in a period from (September 2022 to September 2023). A questionnaire was passed on digitally. Results: The practices of the participants towards experience any side effects while taking medication (28.9%) abandon the medication, while (28.2%) consult to physician, (19.6%) consult to the pharmacist, (13.2%) discontinue the course of the medication and start a new one with the same affect, (6.2%) consult to the family, 3.9% do nothing. Conclusions: The understanding, perspective, and behaviors of self-medication and drugs among medical students are substantially low with increasing use of self-prescribed medications, and antibiotics.","PeriodicalId":18393,"journal":{"name":"Medical Science","volume":"113 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136381224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Forecasting Severities and Etiology of Acute Pancreatitis by Using Pancreatic Enzymes and Lipase: Amylase Ratio 应用胰酶和脂肪酶:淀粉酶比值预测急性胰腺炎的严重程度和病因
Pub Date : 2023-08-01 DOI: 10.54905/disssi/v27i138/e326ms3151
Kamlesh Taori, Vijendra Kirnake, Parmeshwar Junare, Ravi Daswani, Anusha Gupta, Sagar Bothra, Nikhil Pantbalekundri, Sourya Acharya
Background: Acute pancreatitis is a common disease with raising incidence and is potentially a life-threatening condition. Many patients with alcohol related pancreatitis were misdiagnosed as gallstone related pancreatitis. Early identification of such aetiology of pancreatitis was essential for prevention of unnecessary interventional procedure (like ERCP), which was less useful in pancreatitis patients of alcoholic origin. So, this study was under taken with aim to find out cause of acute pancreatitis by using pancreatic enzymes and Lipase: Amylase ratio. Additionally, the study aimed to assess the predictive value of these markers in determining the severity of pancreatitis. Material and methods: Present observational study was done at Medical Gastroenterology Department at Acharya Vinoba Bhave Rural Hospital, Wardha, India over 1 year period. Total 84 acute pancreatitis patients, who satisfied inclusion and exclusion criteria were selected and assessed for serum Amylase & Lipase and Lipase: Amylase ratio. Results: In current study, average patients age was 41.1 ± 12.7 years, where majority of patients were males (82%) and all alcoholic pancreatitis patients were also male (p<0.05). Most common etiology for acute pancreatitis was alcohol i.e., 48.8% followed by idiopathic cause around 31%, gall stone disease (16.7%), and others. There were non-significantly lower levels of serum lipase, serum amylase and serum lipase/amylase ratio among alcoholic pancreatitis and severe pancreatitis patients compared to their counterpart (p>0.05). Conclusion: Pancreatitis enzymes and Lipase: Amylase ratio was not much effective in predicting etiology and severity in patients of acute pancreatitis.
{"title":"Forecasting Severities and Etiology of Acute Pancreatitis by Using Pancreatic Enzymes and Lipase: Amylase Ratio","authors":"Kamlesh Taori, Vijendra Kirnake, Parmeshwar Junare, Ravi Daswani, Anusha Gupta, Sagar Bothra, Nikhil Pantbalekundri, Sourya Acharya","doi":"10.54905/disssi/v27i138/e326ms3151","DOIUrl":"https://doi.org/10.54905/disssi/v27i138/e326ms3151","url":null,"abstract":"Background: Acute pancreatitis is a common disease with raising incidence and is potentially a life-threatening condition. Many patients with alcohol related pancreatitis were misdiagnosed as gallstone related pancreatitis. Early identification of such aetiology of pancreatitis was essential for prevention of unnecessary interventional procedure (like ERCP), which was less useful in pancreatitis patients of alcoholic origin. So, this study was under taken with aim to find out cause of acute pancreatitis by using pancreatic enzymes and Lipase: Amylase ratio. Additionally, the study aimed to assess the predictive value of these markers in determining the severity of pancreatitis. Material and methods: Present observational study was done at Medical Gastroenterology Department at Acharya Vinoba Bhave Rural Hospital, Wardha, India over 1 year period. Total 84 acute pancreatitis patients, who satisfied inclusion and exclusion criteria were selected and assessed for serum Amylase & Lipase and Lipase: Amylase ratio. Results: In current study, average patients age was 41.1 ± 12.7 years, where majority of patients were males (82%) and all alcoholic pancreatitis patients were also male (p<0.05). Most common etiology for acute pancreatitis was alcohol i.e., 48.8% followed by idiopathic cause around 31%, gall stone disease (16.7%), and others. There were non-significantly lower levels of serum lipase, serum amylase and serum lipase/amylase ratio among alcoholic pancreatitis and severe pancreatitis patients compared to their counterpart (p>0.05). Conclusion: Pancreatitis enzymes and Lipase: Amylase ratio was not much effective in predicting etiology and severity in patients of acute pancreatitis.","PeriodicalId":18393,"journal":{"name":"Medical Science","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135002739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative study of automatic bolus tracking and manual bolus tracking in triphasic Computed Tomography of the abdomen 腹部三相计算机断层扫描中自动与手动点滴追踪的比较研究
Pub Date : 2023-08-01 DOI: 10.54905/disssi/v27i138/e321ms3107
Amal Shaji, Adarsh KM, Amita Digambar Dabholkar
Background: A computer-assisted bolus tracking system that initiates diagnostic scans prompted by contrast enhancement was recently developed. Using low-dose scans, this technology allows the scans to start, either manually or automatically, when the contrast enhancement rises to a predefined threshold (ROI). We aimed to compare the automatic bolus tracking and manual bolus tracking triphasic contrast enhancement in the abdomen. Materials and Methods: To compare automatic bolus tracking and manual bolus tracking method for contrast enhancement in the Hounsfield Unit of abdominal vessels and measure the delay in contrast enhancement in automatic and manual bolus tracking methods. The studies were conducted in the Department of Radio-diagnosis. 72 participants were included in the study that underwent triphasic CECT abdomen. Results: The Thoracic Aorta (HU) and Abdominal Aorta (HU) of the two groups differ significantly (P value 0.001). There is a substantial difference between the two groups in Hepatic Artery (HU) and Delay Time (S) (P value 0.001). Conclusion: This study revealed that automatic bolus tracking was the most beneficial approach in triphasic CECT Abdomen when compared to manual bolus tracking.
{"title":"Comparative study of automatic bolus tracking and manual bolus tracking in triphasic Computed Tomography of the abdomen","authors":"Amal Shaji, Adarsh KM, Amita Digambar Dabholkar","doi":"10.54905/disssi/v27i138/e321ms3107","DOIUrl":"https://doi.org/10.54905/disssi/v27i138/e321ms3107","url":null,"abstract":"Background: A computer-assisted bolus tracking system that initiates diagnostic scans prompted by contrast enhancement was recently developed. Using low-dose scans, this technology allows the scans to start, either manually or automatically, when the contrast enhancement rises to a predefined threshold (ROI). We aimed to compare the automatic bolus tracking and manual bolus tracking triphasic contrast enhancement in the abdomen. Materials and Methods: To compare automatic bolus tracking and manual bolus tracking method for contrast enhancement in the Hounsfield Unit of abdominal vessels and measure the delay in contrast enhancement in automatic and manual bolus tracking methods. The studies were conducted in the Department of Radio-diagnosis. 72 participants were included in the study that underwent triphasic CECT abdomen. Results: The Thoracic Aorta (HU) and Abdominal Aorta (HU) of the two groups differ significantly (P value 0.001). There is a substantial difference between the two groups in Hepatic Artery (HU) and Delay Time (S) (P value 0.001). Conclusion: This study revealed that automatic bolus tracking was the most beneficial approach in triphasic CECT Abdomen when compared to manual bolus tracking.","PeriodicalId":18393,"journal":{"name":"Medical Science","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135002744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Public knowledge, attitude and practice of complementary and alternative medicine in Makkah city, Saudi Arabia 沙特阿拉伯麦加市补充和替代医学的公众知识、态度和实践
Pub Date : 2023-08-01 DOI: 10.54905/disssi/v27i138/e318ms3169
Raghad Majed Hariri, Khulood Waleed Melebari, Aljoharah Abdullah Alqahtani, Bushra Ahmed Shaikh, Rasha Ibrahim Kutbi, Mayyas Abdulaziz Alnajmi, Yazan Hussain Shahat, Osama Abdullah Abdulrahman, Mokhtar Mahfouz Shatla
Background and aim: Complementary and Alternative Medicine (CAM) is commonly practiced, and Makkah city being a religious site has more diversity and access to it, which should be addressed and measured. The objective of this study is to assess knowledge, attitude, and practice of various CAM practices in the population of Makkah city, Saudi Arabia. Methods: A web-based cross sectional descriptive study was conducted using a previously validated questionnaire which was translated in Arabic and thereafter distributed via electronic links to the target population. Results: A total of 437 responses were collected fulfilling the inclusion criteria. The participants were ranged from 18 to more than 50 years old, 89.2% of them were females and 95.4% were Saudi. A total of 347 participants had knowledge about CAM and it was observed to be higher among females 80.5% compared to the males 70.2%. 67.5% of the participants reported using CAM and the most reported source of knowledge was family/friends (62.5%), followed by social media (52.2%). 42.9% agreed that CAM is better than conventional medicine for treatment, and 42.8% concurred that it’s safe to use without consulting a medical practitioner. 82.4% think CAM is effective for treatment, and 67.5% regard CAM as safe for use. Conclusion: CAM is widely favored by the citizens of Makkah, Saudi Arabia. Its high prevalence and increased use indicate the need for credible sources to ensure accurate and safe utilization among the citizens.
{"title":"Public knowledge, attitude and practice of complementary and alternative medicine in Makkah city, Saudi Arabia","authors":"Raghad Majed Hariri, Khulood Waleed Melebari, Aljoharah Abdullah Alqahtani, Bushra Ahmed Shaikh, Rasha Ibrahim Kutbi, Mayyas Abdulaziz Alnajmi, Yazan Hussain Shahat, Osama Abdullah Abdulrahman, Mokhtar Mahfouz Shatla","doi":"10.54905/disssi/v27i138/e318ms3169","DOIUrl":"https://doi.org/10.54905/disssi/v27i138/e318ms3169","url":null,"abstract":"Background and aim: Complementary and Alternative Medicine (CAM) is commonly practiced, and Makkah city being a religious site has more diversity and access to it, which should be addressed and measured. The objective of this study is to assess knowledge, attitude, and practice of various CAM practices in the population of Makkah city, Saudi Arabia. Methods: A web-based cross sectional descriptive study was conducted using a previously validated questionnaire which was translated in Arabic and thereafter distributed via electronic links to the target population. Results: A total of 437 responses were collected fulfilling the inclusion criteria. The participants were ranged from 18 to more than 50 years old, 89.2% of them were females and 95.4% were Saudi. A total of 347 participants had knowledge about CAM and it was observed to be higher among females 80.5% compared to the males 70.2%. 67.5% of the participants reported using CAM and the most reported source of knowledge was family/friends (62.5%), followed by social media (52.2%). 42.9% agreed that CAM is better than conventional medicine for treatment, and 42.8% concurred that it’s safe to use without consulting a medical practitioner. 82.4% think CAM is effective for treatment, and 67.5% regard CAM as safe for use. Conclusion: CAM is widely favored by the citizens of Makkah, Saudi Arabia. Its high prevalence and increased use indicate the need for credible sources to ensure accurate and safe utilization among the citizens.","PeriodicalId":18393,"journal":{"name":"Medical Science","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134950910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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