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Penile Compression Release Index Revisited: Evaluation and Comparison with Other Noninvasive Tools in the Prediction of Bladder Outlet Obstruction in Men with Benign Prostatic Enlargement 阴茎压迫释放指数:与其他无创工具预测良性前列腺增大患者膀胱出口梗阻的评价和比较
Pub Date : 2019-04-01 DOI: 10.5455/medarh.2019.73.81-86
Damir Aganović, B. Kulovac, S. Bajramović, A. Kešmer
Aim: To determine the discriminatory power of penile urethral compression-release index (PCRI), clinical prostate score (CLIPS) and bladder outlet obstruction index 2 (BOON2) for the detection of bladder outlet obstruction (BOO), and the associated bladder abnormality in patients with benign prostatic enlargement (BPE). Material and methods: In study was included of 135 patients with proven BPE underwent urodynamic measurement (UDM) and PCR maneuver. PCR Index was calculated following the formula: (Qs-Qss)/Qss x 100(%). CLIPS score was calculated based on non-invasive variables (prostate volume, maximal urinary flow, residual urine and voided volume), while BOON2 was calculated using the formula intravesical prostate protrusion (IPP)-3 x Qmax-0.2 x mean voided volume. UDM results were plotted on Schaefer and URA nomograms. Results: A comparative analysis was made using ROC curves. The area under the curve (AUC) for PCRI is 0.85 (PTP 91.3%), while AUC for CLIPS and BOON2 is 0.8 (PTP 77.6%) and 0.82 (PTP 74.5%), respectively. PCRI with the cut-off point of 96% clearly distinguishes obstructed patients with normocontractile detrusor and the presence of detrusor overactivity (DO), versus those unobstructed. CLIPS (>10) shows good BOO prediction, but without the possibility of distinguishing between detrusor contractility grade and the occurrence of DO. BOON2 has shown that impaired contractility has influence on this number in obstructed patients. Conclusion: PCRI is a very good noninvasive urodynamic test for a group-wise detection of BOO in patients with BPE and associated bladder co-morbidities; it is therefore superior in comparison with to CLIPS or BOON2.
目的:探讨阴茎尿道压释指数(PCRI)、临床前列腺评分(CLIPS)和膀胱出口梗阻指数2 (BOON2)对良性前列腺增大(BPE)患者膀胱出口梗阻(BOO)及相关膀胱异常的鉴别能力。材料和方法:本研究纳入135例经证实的BPE患者进行尿动力学测量(UDM)和PCR操作。PCR指数计算公式为:(Qs-Qss)/Qss × 100(%)。CLIPS评分基于非侵入性变量(前列腺体积、最大尿流量、残余尿量和排尿量)计算,BOON2计算公式为膀胱内前列腺突出(IPP)-3 x Qmax-0.2 x平均排尿量。UDM结果绘制在Schaefer图和URA图上。结果:采用ROC曲线进行比较分析。PCRI的曲线下面积(AUC)为0.85 (PTP为91.3%),CLIPS和BOON2的AUC分别为0.8 (PTP为77.6%)和0.82 (PTP为74.5%)。PCRI的分界点为96%,可以清楚地区分出逼尿肌正常收缩和存在逼尿肌过度活动(DO)的梗阻患者与未梗阻患者。CLIPS(>10)显示出良好的BOO预测,但无法区分逼尿肌收缩等级和DO的发生。BOON2表明,在梗阻患者中,收缩功能受损会影响这一数字。结论:PCRI是一种非常好的无创尿动力学检测方法,可用于BPE和相关膀胱合并症患者的BOO群体检测;因此,与CLIPS或BOON2相比,它更优越。
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引用次数: 3
Marine Isopod Ceratothoa Oestroides Extract: a Novel Treatment for Diabetic Foot Ulcers? Case Report of an Immunosuppressed Patient 海洋等足动物角脚藻提取物:治疗糖尿病足溃疡的新方法?1例免疫抑制患者报告
Pub Date : 2019-04-01 DOI: 10.5455/medarh.2019.73.131-133
E. Meimeti, N. Tentolouris, C. Loupa, V. Roussis, M. Rallis
Introduction: Diabetic foot ulcer (DFU) is a common lower-extremity complication in patients with diabetes mellitus. A novel DFU treatment is tested by using an ointment containing as healing agent olive oil isopod Ceratothoa oestroidesextract. Case report: A 58 years old obese man,smoker, with a history of unregulated Type 2 Diabetes Mellitus, peripheral neuropathy and Hodgkin lymphoma was referred to Athens–Greece university hospital Laikon. The patient presented clinically with a lower extremity DFU and peripheral neuropathy with dysesthesia and disturbed sensation of hot and cold. He was treated with an ointment containing C. oestroides extract for five months, without any antimicrobial treatment. Therapy was evaluated by measurement of the transepidermal water loss, skin hydration, photo documentation and planimetry. At each patient’s visit, DFU presented a satisfactory healing process. Five months after treatment initiation the patient had complete healing of his DFU. Blood tests after treatment revealed a significant reduction of the levels of the inflammatory markers. Ulcer cultures did not reveal any microbial development neither before nor after treatment. Conclusion: The administration of the C. oestroides extract ointment proved to be effective in this case. Although these results should be further investigated, the reported case suggests a novel option for the management of neuropathic diabetic foot ulcers, especially in patients with severe co-morbidities.
糖尿病足溃疡(DFU)是糖尿病患者常见的下肢并发症。一种新的治疗DFU的方法是使用一种软膏作为愈合剂,其中含有橄榄油等足类角藻甾醇提取物。病例报告:一名58岁的肥胖男性,吸烟者,有2型糖尿病、周围神经病变和霍奇金淋巴瘤的病史,被转介到雅典-希腊大学医院Laikon。患者临床表现为下肢DFU和周围神经病变,伴有感觉不良和冷热感觉紊乱。患者使用含有雌甾体提取物的药膏治疗5个月,未进行任何抗菌治疗。通过测量经皮失水、皮肤水化、照片记录和平面测量来评估治疗。在每位患者就诊时,DFU均表现出令人满意的愈合过程。治疗开始5个月后,患者的DFU完全愈合。治疗后的血液检查显示炎症标志物水平显著降低。溃疡培养在治疗前后均未发现任何微生物的发展。结论:黄芪提取物软膏是治疗此病的有效方法。虽然这些结果还有待进一步研究,但报告的病例为神经性糖尿病足溃疡的治疗提供了一种新的选择,特别是在有严重合并症的患者中。
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引用次数: 4
Application of Vitamin E + Coenzyme Q Therapy During FAKO + IOL Implantation 维生素E +辅酶Q在FAKO + IOL植入术中的应用
Pub Date : 2019-04-01 DOI: 10.5455/medarh.2019.73.109-112
Asim Kayiklik
Introduction: Cataract surgery is a widely used procedure around the world. After cataract surgery, one of the important points is that oxidative stress may cause postoperative corneal edema and vision loss. Aim: In this study, we aim to reduce the oxidative stress and related conditions that may develop during intraoperative and postoperative FAKO + IOL implantation. Material and Methods: Total amount of 32 patients with cataract were included to the study. The patients were classified as two groups randomly and the same surgical procedure was applied to the patients in both groups, except using visudrop. Group I was defined as a control group and routine FAKO + IOL implantation surgery was performed. In Group II, after the sideport was opened at the beginning of the operation, 0.5 cc visudrop (coenzyme q + vitamin E + hypermellosis) was given to the anterior camara. After the operation, 0.5 cc visudrop was also given to the anterior camara. Postoperative examination findings were compared statistically. Results: In Group II, postoperative 1st day and postoperative 7th day visual acuities were significantly higher than in Group I. In Group II, postoperative 1st day and postoperative 7th day visual acuity increments were significantly higher than in Group I. In Group I, postoperative 1st day and 7th day pachymetry value increments were significantly higher than in Group II. Conclusion: Using visudrop during the FAKO + IOL implantation may be an effective method for postoperative corneal edema and vision.
白内障手术是世界范围内广泛应用的手术。白内障手术后,很重要的一点是氧化应激可能导致术后角膜水肿和视力下降。目的:在本研究中,我们旨在减少FAKO + IOL植入术中和术后可能发生的氧化应激及相关情况。材料与方法:选取32例白内障患者作为研究对象。将患者随机分为两组,除使用视药水外,两组患者均采用相同的手术方法。第一组为对照组,行常规FAKO + IOL植入术。II组在手术开始时打开侧孔后,给予前照相机0.5 cc滴视液(辅酶q +维生素E +多菌液)。术后给予前相机0.5 cc滴视液。对术后检查结果进行统计学比较。结果:组术后第1天、第7天的视力均显著高于组。组术后第1天、第7天的视力增量均显著高于组。组术后第1天、第7天的视厚测量值增量均显著高于组。结论:FAKO + IOL植入术中使用滴视剂是治疗术后角膜水肿和视力的有效方法。
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引用次数: 4
Prof Amela Kulenovic, MD, PhD (1956-2018) Amela Kulenovic教授,医学博士(1956-2018)
Pub Date : 2019-02-01 DOI: 10.5455/medarh.2019.73.64-64
I. Masic
On the October 31st, 2018 passed away Amela Kulenovic, full professor of Faculty of medicine of University of Sarajevo. Professor Amela Kulenovic was born in Sarajevo in 1956. She finished Grammar school and Gymnasium in Sarajevo. She graduated at the Faculty of medicine of University of Sarajevo in the 1980. During a period from 1978 to 1981, she worked as demonstrator at Cathedra of Anatomy of the Faculty of medicine at Sarajevo University. Since 1981 until 1982, she worked as associate assistant at the same Cathedra.
2018年10月31日,萨拉热窝大学医学院正教授Amela Kulenovic去世。Amela Kulenovic教授1956年出生于萨拉热窝。她在萨拉热窝读完了文法学校和体育馆。1980年代毕业于萨拉热窝大学医学院。在1978年至1981年期间,她在萨拉热窝大学医学院解剖中心担任示威者。从1981年到1982年,她在同一座教堂担任副助理。
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引用次数: 0
Prof Kasim Muminhodzic, MD, PhD (1941-2017) Kasim Muminhodzic教授,医学博士(1941-2017)
Pub Date : 2018-10-01 DOI: 10.5455/medarh.2018.72.308-308
I. Masic
In December of the 2017 passed away Kasim Muminhodzic, professor emeritus of the Faculty of Medicine, University of Tuzla, on the subject of Gastroenterology. He was born in Lukavac near Tuzla in 1941. Graduated at the Medical Faculty in Belgrade, then the capital of former Yugoslavia. Completed specialization in Internal Medicine at one of the most prestigious medical institutions in the former Yugoslavia–the Military Medical Academy (MMA) in Belgrade.
2017年12月,图兹拉大学医学院胃肠病学荣誉教授Kasim Muminhodzic去世。他于1941年出生在图兹拉附近的卢卡瓦茨。毕业于前南斯拉夫首都贝尔格莱德的医学院。在贝尔格莱德前YugoslaviaÂ-the军事医学学院最负盛名的医疗机构之一完成内科专业。
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引用次数: 0
In Memoriam: Prof Smail Zubcevic, MD, PhD (1958-2017). 纪念:Smail Zubcevic教授,医学博士(1958-2017)。
Pub Date : 2018-01-01 DOI: 10.5455/medarh.2018.72.76-76
Z. Begić
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引用次数: 0
Biographical Lexicon of Medical Informatics, Third Edition 医学信息学传记词典,第三版
Pub Date : 2017-08-01 DOI: 10.5455/MEDARH.2017.71.296-296
M. Ball
...It is with pleasure I commend to you our colleagues and friends your impressive effort in putting together the third edition of your book “Biographical Lexicon of Medical Informatics”, that document the lives and accomplishments of so many of our colleagues and friends around the world.
…我很高兴地向你,我们的同事和朋友们赞扬你在编纂第三版《医学信息学传记词典》方面所做的令人印象深刻的努力,这本书记录了我们在世界各地的许多同事和朋友的生活和成就。
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引用次数: 6
Prof Ismet Ceric, MD, PhD (1935-2017) Ismet Ceric教授,医学博士(1935-2017)
Pub Date : 2017-04-01 DOI: 10.5455/MEDARH.2017.71.158-159
I. Masic
Professor Ismet Ceric, MD, PhD, was one of the last representatives of the recognizable Sarajevo Neuropsychiatry School in the former Yugoslav territory, which was founded by Professor Nedo Zec (1899-1971) in 1946/47 with professors Dimitrije Dimitrijevic (1900-1989), Josip Horvat (1911-1964), Salih Ridjanovic, Slobodan Loga (1936-), Dusan Kecmanovic (1940-2014) and others.
Ismet Ceric教授,医学博士和博士,是前南斯拉夫领土上公认的萨拉热窝神经精神病学学院的最后代表之一,该学院由Nedo Zec教授(1899-1971)于1946/47年与Dimitrije Dimitrijevic(1900-1989)、Josip Horvat(1911-1964)、Salih Ridjanovic、Slobodan Loga(1936-)、Dusan Kecmanovic(1940-2014)等教授共同创立。
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引用次数: 0
Embitterment in War Veterans with Posttraumatic Stress Disorder 患有创伤后应激障碍的退伍军人的怨恨
Pub Date : 2017-04-01 DOI: 10.1016/j.eurpsy.2017.02.354
D. Sabic, A. Šabić, Olivera Batić-Mujanović
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引用次数: 3
Frequency of Bacterial Samples from Patients with Chronic Acquired Nasolacrimal Duct Obstruction 慢性获得性鼻泪管梗阻患者细菌标本的频率分析
Pub Date : 2016-12-01 DOI: 10.5455/medarh.2016.70.433-436
K. Shahraki, Ali Makateb, Keyvan Shirzadi, K. Khosravifard
Introduction: Dacryocystitis is an infection of lacremical sac due to obstruction of nasolacrimal duct which has primary or secondary causes. Idiopathic inflammatory obstruction is the primary cause. Trauma, infection, inflammation, neoplasia, and mechanical obstruction are secondary one. Aim: The objective of this study is determination of bacterial samples from patients with chronic acquired nasolacrimal duct obstruction. Methods: This cross-sectional study was contained 90 patients with dacryocystitis from 2010 to 2011, in Besat hospital. Convenience sampling in sterile condition sampling was performed by sterile swab from the pus out of the lacrimal sac. Blood agar, EMB, chocolate agar, and thioglycolate broth were used for bacterial cultivation. Various antibiotics were used for antibiotic resistance study. Finally, statistical analysis was done by SPSS ver. 15. Results: In this study, the mean age of participants was 49.36 ± 12.18 years. Number of male and female patients was equal and Sampling was performed in 53.3% of patients from the right eye. The most frequent bacteria were Staphylococcus, E. coli, and Enterobacteriaceae, respectively. Also, our results show most of bacteria obtained from patients eye pus are sensitive to chloramphenicol and the most antibiotic resistance was for co-trimoxazole. Conclusion: Our results illustrated gram-positive bacteria have an important role in dacryocystitis which is confirm previous studies. Although our results indicated chloramphenicol is the best choice for treatment process, but it is notable due to the variety of bacteria which can cause this disease, identification of bacterial contamination can be a great help to choose the best treatment process.
简介:泪囊炎是一种由鼻泪管阻塞引起的泪囊感染,有原发或继发原因。特发性炎性梗阻是主要原因。其次是外伤、感染、炎症、肿瘤、机械性梗阻。目的:对慢性获得性鼻泪管梗阻患者进行细菌检测。方法:对2010 ~ 2011年在贝萨特医院就诊的90例泪囊炎患者进行横断面研究。在无菌条件下方便取样,用无菌拭子从泪囊流出的脓液中取样。用血琼脂、EMB、巧克力琼脂和巯基乙酸肉汤培养细菌。采用多种抗生素进行耐药性研究。最后用SPSS软件进行统计分析。15. 结果:研究对象平均年龄49.36±12.18岁。男性和女性人数相等,53.3%的患者从右眼取样。最常见的细菌分别是葡萄球菌、大肠杆菌和肠杆菌科。此外,我们的研究结果显示,从患者眼脓液中获得的细菌大多数对氯霉素敏感,而对复方新诺明的耐药性最大。结论:革兰氏阳性菌在泪囊炎中起重要作用,证实了前人的研究。虽然我们的结果表明氯霉素是治疗工艺的最佳选择,但值得注意的是,由于引起该病的细菌种类繁多,细菌污染的鉴定可以极大地帮助选择最佳治疗工艺。
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引用次数: 7
期刊
Medical Archives
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