Pub Date : 2021-09-01DOI: 10.1136/rapm-2021-esra.231
B. Quirós, LH Rocio, PH María Asunción
Background and Aims Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit cycloxygenasa and it causes granulocytic function suppressio (1). These effects could be found in relation to the increased incidence of infections and higher risk of bleeding (2). Aim of this study was a descriptive analysis of risk factors for total knee arthroplasty, in order to evaluate the relationship between NSAIDs and perioperative infection (4). Methods A descriptive observational study in 25 patients medical records who were scheduled for total knee arthroplasty in University Hospital of Valladolid. The following variables were collected (table 1). The study was aprobed by Hospital Clinico Universitario de Valladolid with number (CEIm PI 19/1438). All patients signed the inform consent to enter the study. Results Statistically significant differences were found in the rate of infection with respect to sex; being more frequent the infections in the feminine sex (p=0.042). Marginally significant differences were found between the taking of NSAIDs and infection of the prosthesis (p=0.1) although there was no statistical significance between the taking of NSAIDs and the analytical parameters of infection. This study demonstrates that periarticular infiltration does not increase the risk of infection (p Conclusions The use of NSAIDs has been associated with an immunosuppressive effect that leads to an increased risk of infection in total knee arthroplasty, so its use in the preoperative period should be limited. Female gender is other significative risk factor too. Our retrospective study has shown relationship between AINEs use and infection after knee arthroplasty.No increased risk of bleeding with AINEs in this sample.
背景和目的非甾体类抗炎药(NSAIDs)抑制环氧生成并导致粒细胞功能抑制(1)。这些影响可能与感染发生率增加和出血风险增加有关(2)。本研究的目的是描述性分析全膝关节置换术的危险因素。方法对巴利亚多利德大学医院拟行全膝关节置换术的25例患者病历进行描述性观察研究。收集了以下变量(表1)。本研究获得巴利亚多利德大学临床医院批准,编号为CEIm PI 19/1438。所有患者均签署知情同意书进入研究。结果两性感染率差异有统计学意义;女性感染率较高(p=0.042)。非甾体抗炎药的使用与假体感染之间差异有统计学意义(p=0.1),但非甾体抗炎药的使用与假体感染的分析参数之间差异无统计学意义。本研究表明关节周围浸润不会增加感染风险(p结论:非甾体抗炎药的使用与免疫抑制作用相关,导致全膝关节置换术中感染风险增加,因此应限制其在术前的使用。女性性别也是另一个重要的风险因素。我们的回顾性研究显示了膝关节置换术后使用aine与感染之间的关系。本样本中AINEs未增加出血风险。
{"title":"231 Infection after knee artroplasty, do we know all risk factors?","authors":"B. Quirós, LH Rocio, PH María Asunción","doi":"10.1136/rapm-2021-esra.231","DOIUrl":"https://doi.org/10.1136/rapm-2021-esra.231","url":null,"abstract":"Background and Aims Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit cycloxygenasa and it causes granulocytic function suppressio (1). These effects could be found in relation to the increased incidence of infections and higher risk of bleeding (2). Aim of this study was a descriptive analysis of risk factors for total knee arthroplasty, in order to evaluate the relationship between NSAIDs and perioperative infection (4). Methods A descriptive observational study in 25 patients medical records who were scheduled for total knee arthroplasty in University Hospital of Valladolid. The following variables were collected (table 1). The study was aprobed by Hospital Clinico Universitario de Valladolid with number (CEIm PI 19/1438). All patients signed the inform consent to enter the study. Results Statistically significant differences were found in the rate of infection with respect to sex; being more frequent the infections in the feminine sex (p=0.042). Marginally significant differences were found between the taking of NSAIDs and infection of the prosthesis (p=0.1) although there was no statistical significance between the taking of NSAIDs and the analytical parameters of infection. This study demonstrates that periarticular infiltration does not increase the risk of infection (p Conclusions The use of NSAIDs has been associated with an immunosuppressive effect that leads to an increased risk of infection in total knee arthroplasty, so its use in the preoperative period should be limited. Female gender is other significative risk factor too. Our retrospective study has shown relationship between AINEs use and infection after knee arthroplasty.No increased risk of bleeding with AINEs in this sample.","PeriodicalId":184382,"journal":{"name":"Postoperative pain management","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128507130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-01DOI: 10.1136/rapm-2021-esra.228
D. Liotiri, N. Attaway, S. Soobhug, W. Caddye
{"title":"228 Opioid sparing anaesthesia and analgesia techniques; a quality improvement project","authors":"D. Liotiri, N. Attaway, S. Soobhug, W. Caddye","doi":"10.1136/rapm-2021-esra.228","DOIUrl":"https://doi.org/10.1136/rapm-2021-esra.228","url":null,"abstract":"","PeriodicalId":184382,"journal":{"name":"Postoperative pain management","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123760836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-01DOI: 10.1136/rapm-2021-esra.224
A. Laudani, R. Gammaldi
{"title":"224 Safety and efficacy of sufentanil sublingual tablet system (SSTS) for postoperative pain (POP) relief after off-pump coronary artery bypass surgery (OPCABG)","authors":"A. Laudani, R. Gammaldi","doi":"10.1136/rapm-2021-esra.224","DOIUrl":"https://doi.org/10.1136/rapm-2021-esra.224","url":null,"abstract":"","PeriodicalId":184382,"journal":{"name":"Postoperative pain management","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126133494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-01DOI: 10.1136/rapm-2021-esra.214
C. Terzulli, C. Chauvin, C. Champagnol Di-Liberti, S. Faisan, A. Dufour, M. Melchior, L. Goffin, D. Graff, E. Laroche, E. Salvat, P. Poisbeau
{"title":"214 Virtual reality hypnosis on cold pain perception in healthy volunteers","authors":"C. Terzulli, C. Chauvin, C. Champagnol Di-Liberti, S. Faisan, A. Dufour, M. Melchior, L. Goffin, D. Graff, E. Laroche, E. Salvat, P. Poisbeau","doi":"10.1136/rapm-2021-esra.214","DOIUrl":"https://doi.org/10.1136/rapm-2021-esra.214","url":null,"abstract":"","PeriodicalId":184382,"journal":{"name":"Postoperative pain management","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120911338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-01DOI: 10.1136/rapm-2021-esra.212
J. Luyt, D. Wagstaff, W. Yap
{"title":"212 Impact of intrathecal diamorphine in enhanced recovery for colorectal surgery; open and laparoscopic","authors":"J. Luyt, D. Wagstaff, W. Yap","doi":"10.1136/rapm-2021-esra.212","DOIUrl":"https://doi.org/10.1136/rapm-2021-esra.212","url":null,"abstract":"","PeriodicalId":184382,"journal":{"name":"Postoperative pain management","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116891755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-01DOI: 10.1136/rapm-2021-esra.223
H. Ahmed, G. Deloughry, K. Joyce, B. O’Donnell, F. Loughnane
{"title":"223 Post operative pain management for hip fracture surgery, a new protocol evaluation","authors":"H. Ahmed, G. Deloughry, K. Joyce, B. O’Donnell, F. Loughnane","doi":"10.1136/rapm-2021-esra.223","DOIUrl":"https://doi.org/10.1136/rapm-2021-esra.223","url":null,"abstract":"","PeriodicalId":184382,"journal":{"name":"Postoperative pain management","volume":"161 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132624665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-01DOI: 10.1136/rapm-2021-esra.215
L. Andjelković Juvan, A. Hostnik, I. Potočnik
{"title":"215 Opioid consumption and neuropathic pain in adjuvant anaesthesia with dexmedetomidine and lidocaine","authors":"L. Andjelković Juvan, A. Hostnik, I. Potočnik","doi":"10.1136/rapm-2021-esra.215","DOIUrl":"https://doi.org/10.1136/rapm-2021-esra.215","url":null,"abstract":"","PeriodicalId":184382,"journal":{"name":"Postoperative pain management","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130455129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-01DOI: 10.1136/rapm-2021-esra.220
G. van Samkar, YR Tan, H. Hermanns, B. Preckel, F. V. Etten, M. Hollmann, M. Stevens
{"title":"220 Comparison of patient controlled versus continuous epidural analgesia in adult surgical patients: a systematic review","authors":"G. van Samkar, YR Tan, H. Hermanns, B. Preckel, F. V. Etten, M. Hollmann, M. Stevens","doi":"10.1136/rapm-2021-esra.220","DOIUrl":"https://doi.org/10.1136/rapm-2021-esra.220","url":null,"abstract":"","PeriodicalId":184382,"journal":{"name":"Postoperative pain management","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133922543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}