Abstract Introduction: Depression is a burdening disease state where up to 30% of individuals do not respond to first-line treatment. Adjunctive use of psychostimulants has been investigated for the treatment of depression in patient populations, including those with treatment-resistant depression or terminal illness. The purpose of this paper is to present a review of the literature on the efficacy of using methylphenidate to manage depression. Methods: A search was conducted in PubMed, Ovid/MEDLINE, and PsychINFO using the following key words: psychostimulants, stimulants, methylphenidate, alternative therapy, depression, and major depressive disorder. All reports included were published before June 30, 2015. Results: For this review 10 reports, including randomized controlled, case series, and retrospective chart review studies, were identified and assessed. Patient populations studied included patients with treatment-resistant depression, patients with terminal illness, geriatric patients, and patient...
{"title":"The role of methylphenidate in depression","authors":"Meghan May, A. Vandenberg","doi":"10.9740/MHC.2015.11.271","DOIUrl":"https://doi.org/10.9740/MHC.2015.11.271","url":null,"abstract":"Abstract Introduction: Depression is a burdening disease state where up to 30% of individuals do not respond to first-line treatment. Adjunctive use of psychostimulants has been investigated for the treatment of depression in patient populations, including those with treatment-resistant depression or terminal illness. The purpose of this paper is to present a review of the literature on the efficacy of using methylphenidate to manage depression. Methods: A search was conducted in PubMed, Ovid/MEDLINE, and PsychINFO using the following key words: psychostimulants, stimulants, methylphenidate, alternative therapy, depression, and major depressive disorder. All reports included were published before June 30, 2015. Results: For this review 10 reports, including randomized controlled, case series, and retrospective chart review studies, were identified and assessed. Patient populations studied included patients with treatment-resistant depression, patients with terminal illness, geriatric patients, and patient...","PeriodicalId":18691,"journal":{"name":"Mental Health Clinician","volume":"28 1","pages":"271-276"},"PeriodicalIF":0.0,"publicationDate":"2015-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75485703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Despite multiple studies evaluating various therapeutic agents, few have emerged as superior agents for the management of alcohol use disorders. As a result, off-label agents, including gabapentin, are being utilized more frequently in clinical practice. Gabapentin has gained popularity as one of the more commonly studied off-label agents. Gabapentin's relatively low abuse potential, side effect profile, and limited hepatic metabolism make it an attractive option compared with benzodiazepines and other anticonvulsants. Several randomized, placebo- and active-controlled trials have evaluated off-label use of gabapentin for the treatment of alcohol detoxification and dependence. Study results and interpretation from the more robust available data are summarized within this article.
{"title":"Off-label use of gabapentin for management of alcohol use disorders","authors":"Taylor A Nichols","doi":"10.9740/MHC.2015.11.248","DOIUrl":"https://doi.org/10.9740/MHC.2015.11.248","url":null,"abstract":"Abstract Despite multiple studies evaluating various therapeutic agents, few have emerged as superior agents for the management of alcohol use disorders. As a result, off-label agents, including gabapentin, are being utilized more frequently in clinical practice. Gabapentin has gained popularity as one of the more commonly studied off-label agents. Gabapentin's relatively low abuse potential, side effect profile, and limited hepatic metabolism make it an attractive option compared with benzodiazepines and other anticonvulsants. Several randomized, placebo- and active-controlled trials have evaluated off-label use of gabapentin for the treatment of alcohol detoxification and dependence. Study results and interpretation from the more robust available data are summarized within this article.","PeriodicalId":18691,"journal":{"name":"Mental Health Clinician","volume":"64 1","pages":"248-252"},"PeriodicalIF":0.0,"publicationDate":"2015-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88928270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Introduction: Suicide is a leading cause of death in the US. Many factors impact suicide and suicide prevention; however, improved awareness, recognition, and depression management account...
{"title":"Evaluation of a depression case management service: Improving depression care and impact on suicide assessment","authors":"J. Hopper","doi":"10.9740/MHC.2015.09.197","DOIUrl":"https://doi.org/10.9740/MHC.2015.09.197","url":null,"abstract":"Abstract Introduction: Suicide is a leading cause of death in the US. Many factors impact suicide and suicide prevention; however, improved awareness, recognition, and depression management account...","PeriodicalId":18691,"journal":{"name":"Mental Health Clinician","volume":"42 1","pages":"197-201"},"PeriodicalIF":0.0,"publicationDate":"2015-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87777974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Introduction: Suicide is currently on the rise with rates increasing alarmingly during the past decade. There are many risk factors for suicidal behavior, and mental illness is at the top ...
{"title":"Lithium and clozapine in suicidality: shedding some light to get out of the dark","authors":"A. Riesselman, E. D. Johnson, E. Palmer","doi":"10.9740/MHC.2015.09.237","DOIUrl":"https://doi.org/10.9740/MHC.2015.09.237","url":null,"abstract":"Abstract Introduction: Suicide is currently on the rise with rates increasing alarmingly during the past decade. There are many risk factors for suicidal behavior, and mental illness is at the top ...","PeriodicalId":18691,"journal":{"name":"Mental Health Clinician","volume":"23 ","pages":"237-243"},"PeriodicalIF":0.0,"publicationDate":"2015-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91452074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Introduction: Suicidal thoughts and behaviors are highly associated with major psychiatric illnesses, including depression, schizophrenia, and substance related disorders.1 Suicide is a ma...
{"title":"A review of electroconvulsive therapy in suicidality","authors":"C. Oji, Troy A Moore, C. A. Gutierrez","doi":"10.9740/MHC.2015.09.212","DOIUrl":"https://doi.org/10.9740/MHC.2015.09.212","url":null,"abstract":"Abstract Introduction: Suicidal thoughts and behaviors are highly associated with major psychiatric illnesses, including depression, schizophrenia, and substance related disorders.1 Suicide is a ma...","PeriodicalId":18691,"journal":{"name":"Mental Health Clinician","volume":"89 1","pages":"212-215"},"PeriodicalIF":0.0,"publicationDate":"2015-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83871803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jessa Koch, Sarah Ward, B. Martin, Christopher J Thomas
Abstract Introduction: The term suicidality describes the multitude of behaviors related to suicide: suicidal ideation, self-injurious behavior, suicide attempt, and completed suicide. Risk factors...
摘要:“自杀”一词描述了与自杀有关的多种行为:自杀意念、自残行为、自杀企图和自杀未遂。风险因素……
{"title":"A review of suicidality in nonpsychotropic medications","authors":"Jessa Koch, Sarah Ward, B. Martin, Christopher J Thomas","doi":"10.9740/MHC.2015.09.224","DOIUrl":"https://doi.org/10.9740/MHC.2015.09.224","url":null,"abstract":"Abstract Introduction: The term suicidality describes the multitude of behaviors related to suicide: suicidal ideation, self-injurious behavior, suicide attempt, and completed suicide. Risk factors...","PeriodicalId":18691,"journal":{"name":"Mental Health Clinician","volume":"7 1","pages":"224-236"},"PeriodicalIF":0.0,"publicationDate":"2015-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90177838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Purpose: The objective of this case summary is to evaluate the potential role of naltrexone in reducing compulsive behaviors in a psychiatric patient. Summary: Naltrexone is an opioid anta...
{"title":"Off-label use of naltrexone for compulsive behavior","authors":"Erika E Tillery, A. Stark","doi":"10.9740/MHC.2015.09.244","DOIUrl":"https://doi.org/10.9740/MHC.2015.09.244","url":null,"abstract":"Abstract Purpose: The objective of this case summary is to evaluate the potential role of naltrexone in reducing compulsive behaviors in a psychiatric patient. Summary: Naltrexone is an opioid anta...","PeriodicalId":18691,"journal":{"name":"Mental Health Clinician","volume":"26 1","pages":"244-247"},"PeriodicalIF":0.0,"publicationDate":"2015-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85129943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Introduction: The first published literature on the topic of antidepressants and suicidality dates back to the mid-1950s. Today, 10 years after the black-box warning was issued, this controversial topic is still debated. This article will review the data behind the black-box warning and its revision; address the subsequent impact the warning had on depression diagnoses, prescribing patterns, follow-up visits, and suicide rates in the United States; and summarize meta-analyses on this topic published since the revised warning was issued in 2007. Methods: A PubMed database search using the MeSH terms Antidepressive Agents and Suicide was conducted from January 2012 through October 2014 to identify articles published on the impact the Food and Drug Administration's black-box warning had on health care at a national level and from January 2007 through October 2014 using the same MeSH terms to identify meta-analyses on the current research regarding the link between antidepressants and suicidality. Se...
{"title":"Antidepressants and suicidality: History, the black-box warning, consequences, and current evidence","authors":"Christopher Noel","doi":"10.9740/MHC.2015.09.202","DOIUrl":"https://doi.org/10.9740/MHC.2015.09.202","url":null,"abstract":"Abstract Introduction: The first published literature on the topic of antidepressants and suicidality dates back to the mid-1950s. Today, 10 years after the black-box warning was issued, this controversial topic is still debated. This article will review the data behind the black-box warning and its revision; address the subsequent impact the warning had on depression diagnoses, prescribing patterns, follow-up visits, and suicide rates in the United States; and summarize meta-analyses on this topic published since the revised warning was issued in 2007. Methods: A PubMed database search using the MeSH terms Antidepressive Agents and Suicide was conducted from January 2012 through October 2014 to identify articles published on the impact the Food and Drug Administration's black-box warning had on health care at a national level and from January 2007 through October 2014 using the same MeSH terms to identify meta-analyses on the current research regarding the link between antidepressants and suicidality. Se...","PeriodicalId":18691,"journal":{"name":"Mental Health Clinician","volume":"30 1","pages":"202-211"},"PeriodicalIF":0.0,"publicationDate":"2015-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72837540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Background: Suicide continues to be a growing public health issue, and suicidal behaviors have been identified as a critical problem in the military population, with the number of soldiers...
背景:自杀一直是一个日益严重的公共卫生问题，自杀行为已被确定为军队人口的一个关键问题。
{"title":"Analysis of suicide attempts and completions at the South Texas Veterans Health Care System: a retrospective review","authors":"Rosana Oliveira, Troy A Moore, C. A. Gutierrez","doi":"10.9740/MHC.2015.09.189","DOIUrl":"https://doi.org/10.9740/MHC.2015.09.189","url":null,"abstract":"Abstract Background: Suicide continues to be a growing public health issue, and suicidal behaviors have been identified as a critical problem in the military population, with the number of soldiers...","PeriodicalId":18691,"journal":{"name":"Mental Health Clinician","volume":"120 1","pages":"189-196"},"PeriodicalIF":0.0,"publicationDate":"2015-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87934753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Introduction: Conducting an accurate suicide risk assessment (SRA) is no simple task as there are a number of factors that influence an individual's level of suicidality and his/her willin...
{"title":"A review of suicide risk assessment instruments and approaches","authors":"M. Lotito, E. Cook","doi":"10.9740/MHC.2015.09.216","DOIUrl":"https://doi.org/10.9740/MHC.2015.09.216","url":null,"abstract":"Abstract Introduction: Conducting an accurate suicide risk assessment (SRA) is no simple task as there are a number of factors that influence an individual's level of suicidality and his/her willin...","PeriodicalId":18691,"journal":{"name":"Mental Health Clinician","volume":"46 1","pages":"216-223"},"PeriodicalIF":0.0,"publicationDate":"2015-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75808830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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