Pub Date : 2024-11-01DOI: 10.1007/s15006-024-4345-x
Olwen Groth, Gabriele Roider, Matthias Graw
Some drugs prolong the QT interval, which can be fatal in the presence of other risk factors. In the 3040 forensic autopsy cases that underwent toxicological analysis over the past five years, in which no certain cause of death could be identified, at least one drug with QT interval prolonging potential was detected in 188 individuals (6%). Risk factors for cardiac events, incl. a history of drug and/or alcohol abuse (45%), pathological cardiovascular changes (66%), and more than one QT-prolonging drug (64%) pointed toward fatal arrhythmic events resulting from the drug, of which antipsychotics were the most prevalent in our cohort.
{"title":"[Drug-induced QT interval prolongation. Evaluating the prevalence of potentially fatal cardiac arrhythmias in a specific cohort of patients].","authors":"Olwen Groth, Gabriele Roider, Matthias Graw","doi":"10.1007/s15006-024-4345-x","DOIUrl":"https://doi.org/10.1007/s15006-024-4345-x","url":null,"abstract":"<p><p>Some drugs prolong the QT interval, which can be fatal in the presence of other risk factors. In the 3040 forensic autopsy cases that underwent toxicological analysis over the past five years, in which no certain cause of death could be identified, at least one drug with QT interval prolonging potential was detected in 188 individuals (6%). Risk factors for cardiac events, incl. a history of drug and/or alcohol abuse (45%), pathological cardiovascular changes (66%), and more than one QT-prolonging drug (64%) pointed toward fatal arrhythmic events resulting from the drug, of which antipsychotics were the most prevalent in our cohort.</p>","PeriodicalId":18692,"journal":{"name":"MMW - Fortschritte der Medizin","volume":"166 19","pages":"48-51"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01DOI: 10.1007/s15006-024-4207-6
Michael Drey, Sven Otto, Friederike Thomasius, Ralf Schmidmaier
{"title":"[The current guideline for osteoporosis: aspects of treating older patients].","authors":"Michael Drey, Sven Otto, Friederike Thomasius, Ralf Schmidmaier","doi":"10.1007/s15006-024-4207-6","DOIUrl":"https://doi.org/10.1007/s15006-024-4207-6","url":null,"abstract":"","PeriodicalId":18692,"journal":{"name":"MMW - Fortschritte der Medizin","volume":"166 Suppl 3","pages":"42-48"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01DOI: 10.1007/s15006-024-4504-0
Lea Stief
{"title":"Amyloid-Antikörper kurz vor der Zulassung.","authors":"Lea Stief","doi":"10.1007/s15006-024-4504-0","DOIUrl":"https://doi.org/10.1007/s15006-024-4504-0","url":null,"abstract":"","PeriodicalId":18692,"journal":{"name":"MMW - Fortschritte der Medizin","volume":"166 20","pages":"11"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142687105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01DOI: 10.1007/s15006-024-4476-0
Thomas Meißner
{"title":"Bei COPD auch das Herz im Blick behalten.","authors":"Thomas Meißner","doi":"10.1007/s15006-024-4476-0","DOIUrl":"https://doi.org/10.1007/s15006-024-4476-0","url":null,"abstract":"","PeriodicalId":18692,"journal":{"name":"MMW - Fortschritte der Medizin","volume":"166 20","pages":"70"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142687316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01DOI: 10.1007/s15006-024-4376-3
Klaus Weckbecker, Markus Bleckwenn
{"title":"[Disputed wound care after a dog bite].","authors":"Klaus Weckbecker, Markus Bleckwenn","doi":"10.1007/s15006-024-4376-3","DOIUrl":"10.1007/s15006-024-4376-3","url":null,"abstract":"","PeriodicalId":18692,"journal":{"name":"MMW - Fortschritte der Medizin","volume":"166 20","pages":"56-59"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142687095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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