Pub Date : 2018-07-22DOI: 10.30799/jnst.141.18040413
K. Buvaneswari, R. Revathy
An environmental friendly approach is employed to synthesize copper oxide nano particles. In the present study copper oxide nanoparticles were synthesized using plant extract of Phyllanthus amarus (kelanelli). The synthesized nanoparticles were characterized using XRD, FT-IR and SEM to understand the structural and morphological characteristics of the copper oxide nanoparticles. The XRD results show that the average crystalline particle size was found to be 26.8 nm and from SEM studies it was found that these nanoparticles exist in cubic structure. CuO nanoparticles have much potential against the pathogens like Pseudomonus sp ., E. coli and Trichoderma sp ., etc.
{"title":"Biosynthesis of Copper Oxide Nanoparticles and Its Antimicrobial Activities","authors":"K. Buvaneswari, R. Revathy","doi":"10.30799/jnst.141.18040413","DOIUrl":"https://doi.org/10.30799/jnst.141.18040413","url":null,"abstract":"An environmental friendly approach is employed to synthesize copper oxide nano particles. In the present study copper oxide nanoparticles were synthesized using plant extract of Phyllanthus amarus (kelanelli). The synthesized nanoparticles were characterized using XRD, FT-IR and SEM to understand the structural and morphological characteristics of the copper oxide nanoparticles. The XRD results show that the average crystalline particle size was found to be 26.8 nm and from SEM studies it was found that these nanoparticles exist in cubic structure. CuO nanoparticles have much potential against the pathogens like Pseudomonus sp ., E. coli and Trichoderma sp ., etc.","PeriodicalId":187599,"journal":{"name":"Journal of Nanoscience and Technology","volume":"51 12","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120855791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-22DOI: 10.30799/jnst.138.18040410
V. Keerthika, A. Ananth, M. Rajan
Zinc oxide nanoparticles were synthesized by a chemical method and characterized by various analytical techniques such as UV-visible spectroscopy, SEM-EDX, XRD, and FTIR. X-ray diffraction and SEM analysis confirmed the formation of well- dispersed zinc oxide nanoparticles with average particle size 22 nm as well as revealed their spherical structure. Chemically synthesized nanoparticles were found to exhibit antibacterial activity against bacterial strains Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus using agar well diffusion method of analysis.
{"title":"Synthesis, Characterization and Antibacterial Activity of Zinc Oxide Nanoparticles","authors":"V. Keerthika, A. Ananth, M. Rajan","doi":"10.30799/jnst.138.18040410","DOIUrl":"https://doi.org/10.30799/jnst.138.18040410","url":null,"abstract":"Zinc oxide nanoparticles were synthesized by a chemical method and characterized by various analytical techniques such as UV-visible spectroscopy, SEM-EDX, XRD, and FTIR. X-ray diffraction and SEM analysis confirmed the formation of well- dispersed zinc oxide nanoparticles with average particle size 22 nm as well as revealed their spherical structure. Chemically synthesized nanoparticles were found to exhibit antibacterial activity against bacterial strains Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus using agar well diffusion method of analysis.","PeriodicalId":187599,"journal":{"name":"Journal of Nanoscience and Technology","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126969328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-22DOI: 10.30799/JNST.135.18040411
P. Prasad, P. Reddy, A. G. Assefa, V. Rao, G. N. Rao
Advances in nanoscience and nanotechnology are centered in the control of size and shape of nanoparticles, as well as attainment of the extended arrangement of nanoparticles in different structures. One dimensional nanostructured magnetic materials are interesting because of their enhanced magnetic properties and potential applications such as information storage and gas sensor. The advanced electronic applications of Fe3O4 magnetic nanomaterials are considered to require improvement in the powder processing, particularly, meticulous particle control in the nanometer range and phase purity. Structural properties of Fe3O4 nanoparticles were synthesized via sol-gel protocol, the morphology and particles size were determined by X-ray diffraction, scanning electron microscope, transmission electron microscope, energy dispersive X-ray, UV- diffuse reflectance spectrophotometer and particle size analyzer. The structure of as prepared Fe3O4 nanoparticles was used for photocatalytic applications.
{"title":"Synthesis and Photocatalytic Studies of Fe3O4 Nanoparticles","authors":"P. Prasad, P. Reddy, A. G. Assefa, V. Rao, G. N. Rao","doi":"10.30799/JNST.135.18040411","DOIUrl":"https://doi.org/10.30799/JNST.135.18040411","url":null,"abstract":"Advances in nanoscience and nanotechnology are centered in the control of size and shape of nanoparticles, as well as attainment of the extended arrangement of nanoparticles in different structures. One dimensional nanostructured magnetic materials are interesting because of their enhanced magnetic properties and potential applications such as information storage and gas sensor. The advanced electronic applications of Fe3O4 magnetic nanomaterials are considered to require improvement in the powder processing, particularly, meticulous particle control in the nanometer range and phase purity. Structural properties of Fe3O4 nanoparticles were synthesized via sol-gel protocol, the morphology and particles size were determined by X-ray diffraction, scanning electron microscope, transmission electron microscope, energy dispersive X-ray, UV- diffuse reflectance spectrophotometer and particle size analyzer. The structure of as prepared Fe3O4 nanoparticles was used for photocatalytic applications.","PeriodicalId":187599,"journal":{"name":"Journal of Nanoscience and Technology","volume":"110 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127552842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-15DOI: 10.30799/jnst.132.18040408
A. Mahmood, Y. Hashim, H. Manap
This paper presents design the optimal channel dimensions for Silicon Fin Feld Effect Transistor (Si-FinFET) for improvement electrical characteristic of Si-FinFET depending on the electrical characteristics of the channel (I ON /I OFF , SS, VT, DIBL). The MuGFET simulation tool has been using to investigate the electrical characteristics of Si-FinFET. The current voltage characteristics has been simulating with different dimensions channel (length, width and oxide thickness). The best channel dimensions of Si-FinFET observed based on electrical characteristics at the working voltage VDD range of 0-5 V. Note that the results with the scaling channel dimensions. Depending on I ON /I OFF ratio higher value, and nearest SS to the ideal SS, the best scaling channel dimensions (K) will be K=0.25 at VDD=5 V and K=0.25 at VDD=0.5 V.
本文根据硅鳍场效应晶体管(Si-FinFET)的电学特性(I on /I OFF, SS, VT, DIBL)，设计了硅鳍场效应晶体管(Si-FinFET)的最佳沟道尺寸，以改善硅鳍场效应晶体管的电学特性。MuGFET仿真工具已被用于研究Si-FinFET的电特性。模拟了不同尺寸通道(长度、宽度和氧化物厚度)的电流电压特性。基于工作电压VDD范围为0-5 V时的电特性，观察到Si-FinFET的最佳沟道尺寸。注意，结果与缩放通道尺寸有关。根据I on /I OFF比较高的值，以及最接近理想SS的SS，最佳缩放通道尺寸(K)将是VDD=5 V时K=0.25和VDD=0.5 V时K=0.25。
{"title":"Nano-Dimensional Properties of Si-FinFET Transistor Based on ION/IOFF Ratio and Subthreshold Swing (SS)","authors":"A. Mahmood, Y. Hashim, H. Manap","doi":"10.30799/jnst.132.18040408","DOIUrl":"https://doi.org/10.30799/jnst.132.18040408","url":null,"abstract":"This paper presents design the optimal channel dimensions for Silicon Fin Feld Effect Transistor (Si-FinFET) for improvement electrical characteristic of Si-FinFET depending on the electrical characteristics of the channel (I ON /I OFF , SS, VT, DIBL). The MuGFET simulation tool has been using to investigate the electrical characteristics of Si-FinFET. The current voltage characteristics has been simulating with different dimensions channel (length, width and oxide thickness). The best channel dimensions of Si-FinFET observed based on electrical characteristics at the working voltage VDD range of 0-5 V. Note that the results with the scaling channel dimensions. Depending on I ON /I OFF ratio higher value, and nearest SS to the ideal SS, the best scaling channel dimensions (K) will be K=0.25 at VDD=5 V and K=0.25 at VDD=0.5 V.","PeriodicalId":187599,"journal":{"name":"Journal of Nanoscience and Technology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121828338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-14DOI: 10.30799/jnst.126.18040407
S. Mamuru, Maxwell Happy
Hazards and toxicity associated with the physical and chemical synthesis protocol of metal nanoparticles has recently led researchers to seek alternative routes that is eco-friendly, cheap and fast; the green chemistry approach where plant extracts and microorganisms are used in the reduction of the metal salt is fast gaining popularity in the field of nanobiotechnology. However, controversy still trails acceptability; furthermore, electrochemical studies on these metal nanoparticles are limited. In this study, silver nitrate was reduced to its “nano silver form” through a one-step synthesis protocol using leaf extract of Senna obtusifolia . The usual microscopic and spectroscopic techniques such as UV-vis., FTIR, SEM, AFM and XRD were used to confirm the formation of silver nanoparticles. Electrochemical characterization using cyclic voltammetry and impedance spectroscopy further reveals the formation of silver nanoparticles via a redox process of Ag 1+ to Ag 0 with a formal potential value of 0.61 V vs. Ag|AgCl 3 M KCl.
最近，金属纳米颗粒的物理和化学合成方案的危害和毒性导致研究人员寻求环保，廉价和快速的替代路线;利用植物提取物和微生物进行金属盐还原的绿色化学方法在纳米生物技术领域得到了迅速发展。然而，争议仍未被接受;此外，对这些金属纳米颗粒的电化学研究是有限的。本研究以番泻叶提取物为原料，通过一步法合成硝酸银为“纳米银”。常用的显微和光谱技术，如紫外-可见。采用FTIR、SEM、AFM、XRD等方法对纳米银的形成进行了表征。利用循环伏安法和阻抗谱进行的电化学表征进一步揭示了Ag 1+到Ag 0的氧化还原过程形成的银纳米颗粒，其形式电位值为0.61 V vs. Ag|AgCl 3 M KCl。
{"title":"Interrogating the Electrochemical Potential of Senna obtusifolia Mediated Biosynthesized Silver Nanoparticles","authors":"S. Mamuru, Maxwell Happy","doi":"10.30799/jnst.126.18040407","DOIUrl":"https://doi.org/10.30799/jnst.126.18040407","url":null,"abstract":"Hazards and toxicity associated with the physical and chemical synthesis protocol of metal nanoparticles has recently led researchers to seek alternative routes that is eco-friendly, cheap and fast; the green chemistry approach where plant extracts and microorganisms are used in the reduction of the metal salt is fast gaining popularity in the field of nanobiotechnology. However, controversy still trails acceptability; furthermore, electrochemical studies on these metal nanoparticles are limited. In this study, silver nitrate was reduced to its “nano silver form” through a one-step synthesis protocol using leaf extract of Senna obtusifolia . The usual microscopic and spectroscopic techniques such as UV-vis., FTIR, SEM, AFM and XRD were used to confirm the formation of silver nanoparticles. Electrochemical characterization using cyclic voltammetry and impedance spectroscopy further reveals the formation of silver nanoparticles via a redox process of Ag 1+ to Ag 0 with a formal potential value of 0.61 V vs. Ag|AgCl 3 M KCl.","PeriodicalId":187599,"journal":{"name":"Journal of Nanoscience and Technology","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128156325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-07DOI: 10.30799/JNST.124.18040406
G. Sudha, A. Balasundaram
Nanoparticles are the basic essential elements in the wall of nanotechnology and it exhibits fabulous advanced characteristic features based on their properties such as size, morphology and other size dependent properties. In this study, marine algae Padina pavonica (Linn.) was used for the biosynthesis of silver nanoparticles. The biosynthesized silver nanoparticles were characterized with UV-vis spectroscopy, FTIR and SEM. The SEM analysis showed the particle size between 20-70 nm as well as the polydispersed spherical structure of the nanoparticles. The extract of marine alga P. pavonica (Linn.) as well as silver nanoparticles were tested against gram positive Staphylococcus aureus, Bacillus subtilis and gram negative bacteria as Escherichia coli and Pseudomonas aeruginos . The P. pavonica based silver nanoparticles significantly inhibited the growth of bacteria. The AgNPs possess potential antibacterial activity than algae extract. This novel highly stable spherical polydispersed Ag nanoparticles were synthesized using a simple environmental friendly green method and can be used for antibacterial agent.
{"title":"Synthesis and Characterization of Silver Nanoparticles using Padina pavonica Extract and Evaluation of Their Antibacterial Activity","authors":"G. Sudha, A. Balasundaram","doi":"10.30799/JNST.124.18040406","DOIUrl":"https://doi.org/10.30799/JNST.124.18040406","url":null,"abstract":"Nanoparticles are the basic essential elements in the wall of nanotechnology and it exhibits fabulous advanced characteristic features based on their properties such as size, morphology and other size dependent properties. In this study, marine algae Padina pavonica (Linn.) was used for the biosynthesis of silver nanoparticles. The biosynthesized silver nanoparticles were characterized with UV-vis spectroscopy, FTIR and SEM. The SEM analysis showed the particle size between 20-70 nm as well as the polydispersed spherical structure of the nanoparticles. The extract of marine alga P. pavonica (Linn.) as well as silver nanoparticles were tested against gram positive Staphylococcus aureus, Bacillus subtilis and gram negative bacteria as Escherichia coli and Pseudomonas aeruginos . The P. pavonica based silver nanoparticles significantly inhibited the growth of bacteria. The AgNPs possess potential antibacterial activity than algae extract. This novel highly stable spherical polydispersed Ag nanoparticles were synthesized using a simple environmental friendly green method and can be used for antibacterial agent.","PeriodicalId":187599,"journal":{"name":"Journal of Nanoscience and Technology","volume":"2 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129375370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-07DOI: 10.30799/JNST.123.18040405
Sherkhane As, . H.H.Suryawanshi, P. Mundada, . B.P.Shinde
Successful cultivation is difficult to pomegranate growers due to Xanthomonas axonopodis pv. punicae which cause bacterial blight disease to pomegranate has become serious threat. However, everyone is looking for solution; this problem is resolved by synthesizing silver nanoparticles by the reduction of silver ions in aqueous solutions with the help of green synthesis method. The causative agent was isolated from the infected pomegranate fruits and was tested with silver nanoparticles which are synthesized from leaf extracts of tulsi and neem; and it was found that silver nanoparticle from tulsi extract with 15 mM concentration showed maximum zone of inhibition 22 mm and 19 mm for neem, while at 1 mM concentration shows minimum. This study showed that synthesized silver nanoparticles are powerful weapon to control the growth of Xanthomonas axonopodis pv. punicae.
{"title":"Silver Nanoparticles: The Powerful Antidote for Bacterial Blight Disease of Pomegranate","authors":"Sherkhane As, . H.H.Suryawanshi, P. Mundada, . B.P.Shinde","doi":"10.30799/JNST.123.18040405","DOIUrl":"https://doi.org/10.30799/JNST.123.18040405","url":null,"abstract":"Successful cultivation is difficult to pomegranate growers due to Xanthomonas axonopodis pv. punicae which cause bacterial blight disease to pomegranate has become serious threat. However, everyone is looking for solution; this problem is resolved by synthesizing silver nanoparticles by the reduction of silver ions in aqueous solutions with the help of green synthesis method. The causative agent was isolated from the infected pomegranate fruits and was tested with silver nanoparticles which are synthesized from leaf extracts of tulsi and neem; and it was found that silver nanoparticle from tulsi extract with 15 mM concentration showed maximum zone of inhibition 22 mm and 19 mm for neem, while at 1 mM concentration shows minimum. This study showed that synthesized silver nanoparticles are powerful weapon to control the growth of Xanthomonas axonopodis pv. punicae.","PeriodicalId":187599,"journal":{"name":"Journal of Nanoscience and Technology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130858212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-21DOI: 10.30799/jnst.106.18040404
K. Pavani, K. Gayathramma, Priyanka Aduri
The extensive use of nanoparticles (NPs) in a variety of applications has raised great concerns about their environmental fate and biological effects. To investigate the role of CuO NPs in soil on microbes and earthworms, we exposed microorganisms and earthworms ( Eisenia fetida ) to different concentrations of CuO NPs E. fetida to CuO NPs is not dose related. Dose related weight loss of earthworms was noticed after 15 days of exposure. This study will be very useful in regulation of nanomaterials that are entering into the environment.
{"title":"Copper Oxide Nanoparticles Toxicity on Eisenia fetida Earthworms and Bacterial Species","authors":"K. Pavani, K. Gayathramma, Priyanka Aduri","doi":"10.30799/jnst.106.18040404","DOIUrl":"https://doi.org/10.30799/jnst.106.18040404","url":null,"abstract":"The extensive use of nanoparticles (NPs) in a variety of applications has raised great concerns about their environmental fate and biological effects. To investigate the role of CuO NPs in soil on microbes and earthworms, we exposed microorganisms and earthworms ( Eisenia fetida ) to different concentrations of CuO NPs E. fetida to CuO NPs is not dose related. Dose related weight loss of earthworms was noticed after 15 days of exposure. This study will be very useful in regulation of nanomaterials that are entering into the environment.","PeriodicalId":187599,"journal":{"name":"Journal of Nanoscience and Technology","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127192448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-20DOI: 10.30799/JNST.120.18040403
P. Santhiyadevi, K. Buvaneswari
In the present work CuMoO 4 and P/CuMoO 4 nanoparticles were synthesized by simple precipitation method. The synthesized molybdate nanoparticles were characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM) and UV-visible diffuse reflectance spectroscopy (UV-vis DRS). XRD results show that the average crystalline size of CuMoO 4 and P/CuMoO 4 nanoparticles were found to be 62.9 nm and 59.7 nm respectively. SEM results showed that CuMoO 4 nanoparticles composed of sphere like structure and P/CuMoO 4 with agglomeration. Four absorption bands at 721, 828, 898 and 967 cm -1 were observed in FT-IR spectrum. The sharp adsorption peak at 270-350 nm was observed in UV–vis DRS technique. The antimicrobial activities of synthesized nanoparticles were observed against various pathogens.
{"title":"Bio-Synthesis and Characterization of Copper Molybdate Nanoparticles","authors":"P. Santhiyadevi, K. Buvaneswari","doi":"10.30799/JNST.120.18040403","DOIUrl":"https://doi.org/10.30799/JNST.120.18040403","url":null,"abstract":"In the present work CuMoO 4 and P/CuMoO 4 nanoparticles were synthesized by simple precipitation method. The synthesized molybdate nanoparticles were characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM) and UV-visible diffuse reflectance spectroscopy (UV-vis DRS). XRD results show that the average crystalline size of CuMoO 4 and P/CuMoO 4 nanoparticles were found to be 62.9 nm and 59.7 nm respectively. SEM results showed that CuMoO 4 nanoparticles composed of sphere like structure and P/CuMoO 4 with agglomeration. Four absorption bands at 721, 828, 898 and 967 cm -1 were observed in FT-IR spectrum. The sharp adsorption peak at 270-350 nm was observed in UV–vis DRS technique. The antimicrobial activities of synthesized nanoparticles were observed against various pathogens.","PeriodicalId":187599,"journal":{"name":"Journal of Nanoscience and Technology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129997019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-13DOI: 10.30799/jnst.125.18040402
Srimoyee Saha, N. Bala, R. Basu, Sukhen Das
Article history: Received 20 May 2018 Accepted 08 June 2018 Available online 13 June 2018 Nanomedicine is widely explored nowadays for treatment of life threatening diseases, yet comes with various challenges and questions. The present study encapsulates the acute toxicological aspects of the Euphorbia thymifolia coupled silver nanoparticles (ET-Ag NP). For acute toxicity studies according to OCED (Organization for Economic Cooperation Development) guidelines Swiss Albino mice (6-8 weeks) were used and were given single intraperitoneal dose of 2000 and 5000 mg/kg body weight and were observed for mortality and other side effects for 14 days. The individual components of the formulation, viz. silver oxide in surface modified nano form and at low dose, and Euphorbia thymifolia are both biocompatible materials. No changes were found for general appearance, behavior and body weight, thus concluding that the nanocomposite formulation does not have single dose toxicity.
{"title":"Acute Toxicity Study of Silver Nanoparticle Coupled with Euphorbia thymifolia","authors":"Srimoyee Saha, N. Bala, R. Basu, Sukhen Das","doi":"10.30799/jnst.125.18040402","DOIUrl":"https://doi.org/10.30799/jnst.125.18040402","url":null,"abstract":"Article history: Received 20 May 2018 Accepted 08 June 2018 Available online 13 June 2018 Nanomedicine is widely explored nowadays for treatment of life threatening diseases, yet comes with various challenges and questions. The present study encapsulates the acute toxicological aspects of the Euphorbia thymifolia coupled silver nanoparticles (ET-Ag NP). For acute toxicity studies according to OCED (Organization for Economic Cooperation Development) guidelines Swiss Albino mice (6-8 weeks) were used and were given single intraperitoneal dose of 2000 and 5000 mg/kg body weight and were observed for mortality and other side effects for 14 days. The individual components of the formulation, viz. silver oxide in surface modified nano form and at low dose, and Euphorbia thymifolia are both biocompatible materials. No changes were found for general appearance, behavior and body weight, thus concluding that the nanocomposite formulation does not have single dose toxicity.","PeriodicalId":187599,"journal":{"name":"Journal of Nanoscience and Technology","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131920853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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