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Osteonecrosis as a manifestation of Long-COVID Syndrome: a systematic review. 作为长COVID综合征一种表现形式的骨坏死:系统综述。
Q1 Medicine Pub Date : 2025-03-01 Epub Date: 2024-08-01 DOI: 10.1007/s12306-024-00854-w
P Za, G F Papalia, P Gregori, S Vasta, R Papalia

Purpose SARS-CoV-2 is an RNA virus responsible for COVID-19 pandemic. Some authors described the set of persistent symptoms COVID-related as "Long-COVID Syndrome." Several cases of post-COVID-19 osteonecrosis (ON) are described. Our primary aim was to study the hypothetical correlation between SARS-CoV-2 infection and ON; our secondary aim was to understand if ON can be considered part of Long-COVID. Materials and methods We performed a systematic review following the Preferred Reporting Items for Systematic Reviewers and Meta-analysis (PRISMA) guidelines. Because COVID-19 is a recently described disease, we included all levels of evidence studies. We excluded studies lacking specification regarding the use of corticosteroids (CCS) and studies not related to COVID-19. The variables extracted were age, sex, risk factors, affected joints, signs and symptoms, magnetic resonance imaging (MRI) and X-ray features, histology, treatment of COVID-19, dose and duration of treatment with CCS, treatment of ON, follow-up, and treatment outcome. Results A total of 13 studies were included, involving 95 patients and 159 joints. Time between the diagnosis of COVID-19 and the onset of symptoms related to ON was 16 weeks on average. Time between the onset of symptoms and the MRI was 6 weeks. An average of 926.4 mg of prednisolone equivalent per patient were administered. On average, CCS were administered for 20.6 days. Conclusions Patients with a history of COVID-19 infection developed osteonecrosis prematurely and with a lower dose of CCS than usually reported in the literature. Symptoms of osteonecrosis occur within the interval of the period described as Long-COVID. Surgeons should not underestimate the persistence of arthralgia when a history of SARS-CoV-2 infection and use of CCS is reported.

目的 SARS-CoV-2 是一种导致 COVID-19 大流行的 RNA 病毒。一些作者将COVID相关的一系列持续性症状描述为 "长COVID综合征"。有多例COVID-19后骨坏死(ON)病例被描述。我们的主要目的是研究SARS-CoV-2感染与骨坏死之间的假定相关性;次要目的是了解骨坏死是否可被视为长COVID的一部分。材料和方法 我们按照《系统综述和元分析首选报告项目》(PRISMA)指南进行了系统综述。由于 COVID-19 是一种新近描述的疾病,我们纳入了所有证据级别的研究。我们排除了缺乏皮质类固醇(CCS)使用规范的研究和与 COVID-19 无关的研究。提取的变量包括年龄、性别、风险因素、受累关节、体征和症状、磁共振成像(MRI)和 X 射线特征、组织学、COVID-19 的治疗、CCS 治疗的剂量和持续时间、ON 的治疗、随访和治疗结果。结果 共纳入 13 项研究,涉及 95 名患者和 159 个关节。从确诊COVID-19到出现ON相关症状的平均时间为16周。症状出现与核磁共振成像之间的时间间隔为6周。每位患者平均使用了 926.4 毫克泼尼松龙当量的药物。平均用药 20.6 天。结论 有COVID-19感染史的患者过早出现骨坏死,且使用的CCS剂量低于文献中通常报道的剂量。骨坏死的症状发生在被描述为长COVID期的时间间隔内。当报告有SARS-CoV-2感染史和使用CCS时,外科医生不应低估关节痛的持续性。
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引用次数: 0
Long-term follow-up of adolescent idiopathic scoliosis surgery with Harrington instrumentations: a systematic review and meta-analysis. 使用哈灵顿器械进行青少年特发性脊柱侧凸手术的长期随访:系统回顾和荟萃分析。
Q1 Medicine Pub Date : 2025-03-01 Epub Date: 2024-05-28 DOI: 10.1007/s12306-024-00836-y
F Barile, A Ruffilli, M Morandi Guaitoli, G Viroli, M Ialuna, M Manzetti, T Cerasoli, E Artioli, M Traversari, A Mazzotti, C Faldini

Purpose: In the 1960s, Harrington instrumentation (HRI) revolutionized the surgical treatment of adolescent idiopathic scoliosis (AIS). Despite the transition to more innovative techniques, concerns regarding its impact on sagittal alignment, associations with low back pain, and correction loss have consistently persisted. The aim of this meta-analysis is precisely to evaluate the clinical and radiological outcomes, as well as the complications of patients treated with HRI over an extended follow-up period. A systematic search of articles about AIS patients who underwent HRI and reported long-term outcomes (> 10 years) was conducted on electronic databases according to PRISMA guidelines. Data regarding radiographic and clinical outcomes were extracted and meta-analyses were performed. Eleven studies comprising 644 patients were included. The mean follow-up ranged from 10.8 to 51.7 years. Radiographic analysis revealed a decrease in the main curve Cobb angle from 60.6° to 38.3°, with a correction loss of - 9.49° between postoperative and last follow-up. Concerning sagittal parameters, preoperative thoracic kyphosis was 19.65° at last follow-up, and preoperative lumbar lordosis was 42.94°. Additional spine surgeries were required in 42% of patients. Clinical outcomes varied among studies, but overall, HRI patients showed comparable quality of life and function to controls, although a higher incidence of low back pain was reported. Patients who underwent HRI exhibited suboptimal correction of rib deformity and a flattened sagittal spinal alignment. However, they generally displayed favourable long-term functional outcomes. Despite the implant's tendency to reduce lumbar curvature, patients achieved good clinical outcomes and functional scores comparable to age-matched individuals, suggesting that disability is not an inevitable consequence of lumbar flattening.

目的:20世纪60年代,哈灵顿器械(HRI)彻底改变了青少年特发性脊柱侧凸(AIS)的手术治疗方法。尽管已过渡到更创新的技术,但有关其对矢状对齐的影响、与腰背痛的关联以及矫正损失的担忧一直存在。本荟萃分析的目的正是为了评估在较长的随访期内接受HRI治疗的患者的临床和放射学结果以及并发症。根据PRISMA指南,我们在电子数据库中对接受HRI治疗的AIS患者的相关文章进行了系统性检索,并对长期疗效(> 10年)进行了报告。提取了有关放射学和临床结果的数据,并进行了荟萃分析。共纳入了 11 项研究,包括 644 名患者。平均随访时间从 10.8 年到 51.7 年不等。放射学分析表明,主曲线Cobb角从60.6°下降到38.3°,术后至最后一次随访期间的矫正损失为-9.49°。在矢状参数方面,术前胸椎后凸在最后一次随访时为 19.65°,术前腰椎前凸为 42.94°。42%的患者需要进行额外的脊柱手术。不同研究的临床结果不尽相同,但总体而言,HRI 患者的生活质量和功能与对照组相当,只是腰背痛的发生率较高。接受 HRI 的患者的肋骨畸形矫正效果不佳,脊柱矢状排列变平。不过,他们普遍表现出良好的长期功能效果。尽管植入物有减少腰椎弯曲的趋势,但患者仍获得了良好的临床效果,其功能评分与年龄匹配者相当,这表明腰椎扁平化并非必然导致残疾。
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引用次数: 0
Conservative versus surgical treatment for displaced olecranon fractures in the elderly: a retrospective study and a review of the literature. 老年人肩胛骨移位骨折的保守治疗与手术治疗:回顾性研究与文献综述。
Q1 Medicine Pub Date : 2025-03-01 Epub Date: 2024-07-31 DOI: 10.1007/s12306-024-00853-x
V Luppi, D Regis, T Maluta, A Sandri, A Trivellato, A Mirabile, B Magnan

Background: Surgery is the gold standard treatment of displaced olecranon fracture, but it presents a high rate of complications, especially in the elderly, including wound breakdown and fixation failure. Conservative treatment of these fractures has recently been proposed with good functional outcomes. The aim of this retrospective study was to compare the functional results and level of satisfaction of displaced olecranon fractures which were managed surgically or conservatively in geriatric patients. The rate of implant removal and reoperation in the surgical group were also calculated.

Materials and methods: Sixteen and eleven patients aged ≥ 75 years (mean 83 and 86.2, respectively) with isolated Mayo IIA or IIB olecranon fracture were surgically and conservatively treated, respectively. All but 1 were females. Due to coronavirus pandemic, they were contacted by phone to validated clinical scores (QuickDASH, PREE and VAS), which were used to assess the outcome.

Results: At an average follow-up of 26.5 months in the conservative group and 53.1 in the surgical group (range 4-82), the mean Quick DASH was 11.67 and 11.2, respectively, while the mean PREE was 11.36 and 12.67, respectively. There was no significant difference in functional outcomes between the two groups, and all patients were satisfied. Seven complications occurred in the surgical cohort (33.3%), requiring reoperation in 4 cases (19%).

Conclusions: Displaced olecranon fractures can successfully be treated conservatively in low-demand geriatric patients with good functional results and high satisfaction rate.

背景:手术是治疗移位性骨折的金标准,但并发症发生率较高,尤其是老年人,包括伤口破裂和固定失败。最近有人提出对这类骨折进行保守治疗,并取得了良好的功能效果。这项回顾性研究旨在比较老年患者手术或保守治疗移位性骨折的功能效果和满意度。研究还计算了手术组的植入物取出率和再次手术率:分别对 16 名和 11 名年龄≥ 75 岁(平均分别为 83 岁和 86.2 岁)的孤立性梅奥 IIA 或 IIB 骨骺骨折患者进行了手术和保守治疗。除 1 人外,其余均为女性。由于冠状病毒大流行,他们通过电话联系进行了临床评分(QuickDASH、PREE 和 VAS),并以此评估疗效:保守治疗组和手术治疗组的平均随访时间分别为 26.5 个月和 53.1 个月(范围为 4-82 个月),Quick DASH 的平均值分别为 11.67 分和 11.2 分,而 PREE 的平均值分别为 11.36 分和 12.67 分。两组患者的功能结果无明显差异,所有患者均表示满意。手术组出现了7例并发症(33.3%),其中4例(19%)需要再次手术:结论:对于需求量小的老年患者,可以成功地采用保守疗法治疗肩胛骨移位性骨折,并取得良好的功能效果和较高的满意度。
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引用次数: 0
No difference in clinical outcomes when retaining or sacrificing the posterior cruciate ligament in medial congruent total knee replacement. A retrospective study. 在内侧同形全膝关节置换术中保留或牺牲后交叉韧带的临床效果无差异。一项回顾性研究。
Q1 Medicine Pub Date : 2025-03-01 Epub Date: 2024-09-04 DOI: 10.1007/s12306-024-00866-6
B C M Foong, W C Lee, S K M Khoo, R Kunnasegaran

Purpose: The aim of this study is to evaluate the effect of retaining or sacrificing the posterior cruciate ligament (PCL) in patients who undergo primary total knee replacement (TKR) with the medial congruent (MC) implant.

Methods: This retrospective study looks at patients who underwent TKR with the MC implant. Comparison was made between the group with the PCL sacrificed (MC-PCLS) and the group with the PCL retained (MC-PCLR). Range of motion (ROM), Oxford knee score (OKS), Knee society knee score (KS-KS) and Knee society function score (KS-FS) were recorded.

Results: The study identified 76 patients. 50 in the MC-PCLS group and 26 in the MC-PCLR group. Both groups had similar patient demographics. Three months postoperatively, OKS and KS-KS had significant improvement. However, there was significant improvement in KS-FS score in the MC-PCLS group but not the MC-PCLR group (MC-PCLR: 33 ± 17, p = 0.07; MC-PCLS: 19 ± 24, p = 0.01). Twelve months postoperatively, the OKS continued to improve significantly for both groups, while the KS-FS and KS-KS scores appeared to stagnate. The ROM continued to improve significantly for the MC-PCLR group but not the MC-PCLS group (MC-PCLR: 7 ± 9, p = 0.03; MC-PCLS: 4 ± 9, p = 0.30). Both groups were similar in ROM, OKS and KSS scores at both the 3 and 12 month post-operative period.

Conclusion: There is no difference in post-operative outcomes with the PCL retained or sacrificed. As such, surgeons can consider routinely sacrificing the PCL for easier balancing of the knee and shorter surgical time.

目的:本研究旨在评估使用内侧同形(MC)假体进行初级全膝关节置换术(TKR)的患者保留或牺牲后交叉韧带(PCL)的效果:这项回顾性研究的对象是使用 MC 假体进行全膝关节置换术的患者。比较了牺牲 PCL 组(MC-PCLS)和保留 PCL 组(MC-PCLR)。研究记录了患者的活动范围(ROM)、牛津膝关节评分(OKS)、膝关节协会膝关节评分(KS-KS)和膝关节协会功能评分(KS-FS):研究发现了 76 名患者。MC-PCLS组50人,MC-PCLR组26人。两组患者的人口统计学特征相似。术后三个月,OKS 和 KS-KS 均有显著改善。但是,MC-PCLS 组的 KS-FS 评分有明显改善,而 MC-PCLR 组没有(MC-PCLR:33 ± 17,p = 0.07;MC-PCLS:19 ± 24,p = 0.01)。术后 12 个月,两组的 OKS 均继续显著改善,而 KS-FS 和 KS-KS 分数似乎停滞不前。MC-PCLR 组的 ROM 继续明显改善,而 MC-PCLS 组则没有(MC-PCLR:7 ± 9,p = 0.03;MC-PCLS:4 ± 9,p = 0.30)。两组在术后 3 个月和 12 个月的 ROM、OKS 和 KSS 评分相似:结论:保留或牺牲 PCL 对术后效果没有影响。因此,外科医生可以考虑常规牺牲 PCL,以便更轻松地平衡膝关节并缩短手术时间。
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引用次数: 0
Multicenter survey about leg length discrepancy and total hip arthroplasty: postoperative management. 关于腿长不一致和全髋关节置换术的多中心调查:术后管理。
Q1 Medicine Pub Date : 2025-03-01 Epub Date: 2024-08-07 DOI: 10.1007/s12306-024-00855-9
D Stimolo, S Lo Giudice, F Matassi, M Innocenti, R Civinini, F Boniforti

Background: We created a Multicenter Survey for Italian orthopedics surgeons on how they approach leg length discrepancy when dealing with primary total hip arthroplasty. Aim of the study was to show how surgeons manage LLD and follow literature recommendations during clinical practice.

Methods: The Survey was composed of 25 questions divided in 4 sections: surgeon's profile, preoperative and intraoperative evaluation, postoperative management. In this paper, we report the absolute and relative frequencies of answers to section on "postoperative management." Then, regarding the treatment of residual LLD, we reported whether trauma surgeons and experts in replacement surgery had higher odds ratios for providing "literature-based" answers compared to orthopedics physicians.

Results: Only four questions received more than 70% agreement on one of the answers. The OR for giving the "literature-based" answer, taking OP as the reference group was 1.57 for TR and 1.72 for RS for 10 mm LLD at first follow-up (FU) and 1.23 TR and 1.32 RS when 20 mm. When 10 mm LLD at 3 months FU the OR was 0.88 TR and 1.15 RS. The OR for treatment of LLD after the first examination of a new patient was 2.16 TR and 1.85 RS.

Conclusions: LLD is a debated topic with no definitive recommendations. Many decisions still depend on tradition. Treatment of LLD during clinical practice often differs from literature recommendations.

背景:我们针对意大利骨科外科医生开展了一项多中心调查,以了解他们在进行初级全髋关节置换术时如何处理腿长不一致问题。该研究旨在展示外科医生在临床实践中如何处理腿长不一致问题并遵循文献建议:调查由 25 个问题组成,分为 4 个部分:外科医生简介、术前和术中评估、术后管理。本文报告了 "术后管理 "部分答案的绝对频率和相对频率。然后,关于残留 LLD 的治疗,我们报告了创伤外科医生和置换手术专家提供 "基于文献 "答案的几率是否高于骨科医生:结果:只有四个问题的其中一个答案的同意率超过 70%。以 OP 为参照组,首次随访(FU)时,当 LLD 为 10 mm 时,给出 "基于文献 "答案的比率分别为 1.57(TR)和 1.72(RS);当 LLD 为 20 mm 时,给出 "基于文献 "答案的比率分别为 1.23(TR)和 1.32(RS)。首次随访(FU)时,当 LLD 为 10 mm 时,OR 为 0.88 TR 和 1.15 RS。新患者首次检查后治疗 LLD 的 OR 为 2.16 TR 和 1.85 RS:LLD是一个备受争议的话题,目前尚无明确的建议。许多决定仍取决于传统。临床实践中对 LLD 的治疗往往与文献建议不同。
{"title":"Multicenter survey about leg length discrepancy and total hip arthroplasty: postoperative management.","authors":"D Stimolo, S Lo Giudice, F Matassi, M Innocenti, R Civinini, F Boniforti","doi":"10.1007/s12306-024-00855-9","DOIUrl":"10.1007/s12306-024-00855-9","url":null,"abstract":"<p><strong>Background: </strong>We created a Multicenter Survey for Italian orthopedics surgeons on how they approach leg length discrepancy when dealing with primary total hip arthroplasty. Aim of the study was to show how surgeons manage LLD and follow literature recommendations during clinical practice.</p><p><strong>Methods: </strong>The Survey was composed of 25 questions divided in 4 sections: surgeon's profile, preoperative and intraoperative evaluation, postoperative management. In this paper, we report the absolute and relative frequencies of answers to section on \"postoperative management.\" Then, regarding the treatment of residual LLD, we reported whether trauma surgeons and experts in replacement surgery had higher odds ratios for providing \"literature-based\" answers compared to orthopedics physicians.</p><p><strong>Results: </strong>Only four questions received more than 70% agreement on one of the answers. The OR for giving the \"literature-based\" answer, taking OP as the reference group was 1.57 for TR and 1.72 for RS for 10 mm LLD at first follow-up (FU) and 1.23 TR and 1.32 RS when 20 mm. When 10 mm LLD at 3 months FU the OR was 0.88 TR and 1.15 RS. The OR for treatment of LLD after the first examination of a new patient was 2.16 TR and 1.85 RS.</p><p><strong>Conclusions: </strong>LLD is a debated topic with no definitive recommendations. Many decisions still depend on tradition. Treatment of LLD during clinical practice often differs from literature recommendations.</p>","PeriodicalId":18875,"journal":{"name":"MUSCULOSKELETAL SURGERY","volume":" ","pages":"89-96"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11876231/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141897792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Magnum metal-on-metal uncemented total hip replacement: 8- to 18-year outcomes of 211 cases. Magnum 金属非骨水泥全髋关节置换术:211 例病例的 8 至 18 年疗效。
Q1 Medicine Pub Date : 2024-12-01 Epub Date: 2024-06-04 DOI: 10.1007/s12306-024-00831-3
D Gaillard-Campbell, T Gross

Background: Reports of adverse reactions to metal debris contributed in part to a decline in use of large-bearing metal-on-metal total hip devices. We hypothesize an optimal trunnion design may reduce risk of this failure mode in large-bearing total hip arthroplasty systems. The purpose of this study is to report mid- to long-term outcomes for a single-surgeon series of 211 total hip arthroplasties using the large-bearing Biomet Magnum metal-on-metal system.

Materials and methods: Between December 2004 and January 2016, the primary surgeon performed 211 uncemented Magnum total hip arthroplasties in 181 patients. The average length of follow-up was 10.1 ± 3.5 years (range 8-18 years).

Results: Using failure of any component as the endpoint, the overall survivorship rate was 98.1% at 10 years and 97.4% at 18 years. These eight failures (3.8% of cohort) included one case of adverse wear-related failure (0.5%), two cases of acetabular ingrowth failure (0.9%), three cases of trunnion corrosion (1.4%), one failure of late infection (0.5%), and one inappropriate revision of components for trochanteric nonunion without instability (0.5%). Excluding failed cases, all components were radiographically stable with no radiolucencies. Except for the one wear failure, ion testing revealed that 97.2% of cases were within optimal whole blood metal ion levels with the remaining ion test results within acceptable levels.

Conclusions: With the uncemented Magnum metal-on-metal total hip, we achieved 97.4% 18-year implant survivorship, exceeding the NICE criteria and registry benchmarks for implant survivorship. We observed a trunnion corrosion rate of 1.4% and no cases of instability. The single case of adverse wear-related failure was caused by acetabular component malposition.

背景:有关金属碎片不良反应的报道在一定程度上导致了大承载金属全髋关节装置使用率的下降。我们假设最佳的耳轴设计可以降低大承重全髋关节置换系统出现这种故障模式的风险。本研究的目的是报告使用大承重Biomet Magnum金属全髋关节置换系统的211例全髋关节置换手术的中长期结果:2004年12月至2016年1月期间,主刀医生为181名患者实施了211例非骨水泥Magnum全髋关节置换术。平均随访时间为 10.1 ± 3.5 年(8-18 年不等):结果:以任何组件的失败作为终点,10 年的总体存活率为 98.1%,18 年的总体存活率为 97.4%。这8例失败病例(占队列的3.8%)包括1例与磨损相关的不良失败(0.5%)、2例髋臼嵌生失败(0.9%)、3例耳轴腐蚀(1.4%)、1例晚期感染失败(0.5%)以及1例因转子不连接而进行的不适当的组件翻修(0.5%)。除去失败的病例,所有组件在影像学上都是稳定的,没有放射性缺陷。除一个磨损失败的病例外,离子检测显示97.2%的病例全血金属离子含量在最佳范围内,其余离子检测结果均在可接受范围内:通过使用非骨水泥Magnum金属全髋关节,我们实现了97.4%的18年植入存活率,超过了NICE标准和植入存活率登记基准。我们观察到耳轴腐蚀率为 1.4%,没有不稳定病例。唯一一例与磨损相关的不良故障是由髋臼组件错位引起的。
{"title":"Magnum metal-on-metal uncemented total hip replacement: 8- to 18-year outcomes of 211 cases.","authors":"D Gaillard-Campbell, T Gross","doi":"10.1007/s12306-024-00831-3","DOIUrl":"10.1007/s12306-024-00831-3","url":null,"abstract":"<p><strong>Background: </strong>Reports of adverse reactions to metal debris contributed in part to a decline in use of large-bearing metal-on-metal total hip devices. We hypothesize an optimal trunnion design may reduce risk of this failure mode in large-bearing total hip arthroplasty systems. The purpose of this study is to report mid- to long-term outcomes for a single-surgeon series of 211 total hip arthroplasties using the large-bearing Biomet Magnum metal-on-metal system.</p><p><strong>Materials and methods: </strong>Between December 2004 and January 2016, the primary surgeon performed 211 uncemented Magnum total hip arthroplasties in 181 patients. The average length of follow-up was 10.1 ± 3.5 years (range 8-18 years).</p><p><strong>Results: </strong>Using failure of any component as the endpoint, the overall survivorship rate was 98.1% at 10 years and 97.4% at 18 years. These eight failures (3.8% of cohort) included one case of adverse wear-related failure (0.5%), two cases of acetabular ingrowth failure (0.9%), three cases of trunnion corrosion (1.4%), one failure of late infection (0.5%), and one inappropriate revision of components for trochanteric nonunion without instability (0.5%). Excluding failed cases, all components were radiographically stable with no radiolucencies. Except for the one wear failure, ion testing revealed that 97.2% of cases were within optimal whole blood metal ion levels with the remaining ion test results within acceptable levels.</p><p><strong>Conclusions: </strong>With the uncemented Magnum metal-on-metal total hip, we achieved 97.4% 18-year implant survivorship, exceeding the NICE criteria and registry benchmarks for implant survivorship. We observed a trunnion corrosion rate of 1.4% and no cases of instability. The single case of adverse wear-related failure was caused by acetabular component malposition.</p>","PeriodicalId":18875,"journal":{"name":"MUSCULOSKELETAL SURGERY","volume":" ","pages":"449-457"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11582121/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141238074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
GPT-based chatbot tools are still unreliable in the management of prosthetic joint infections. 基于 GPT 的聊天机器人工具在假体关节感染管理方面仍不可靠。
Q1 Medicine Pub Date : 2024-12-01 Epub Date: 2024-07-02 DOI: 10.1007/s12306-024-00846-w
M Bortoli, M Fiore, S Tedeschi, V Oliveira, R Sousa, A Bruschi, D A Campanacci, P Viale, M De Paolis, A Sambri

Background: Artificial intelligence chatbot tools responses might discern patterns and correlations that may elude human observation, leading to more accurate and timely interventions. However, their reliability to answer healthcare-related questions is still debated. This study aimed to assess the performance of the three versions of GPT-based chatbots about prosthetic joint infections (PJI).

Methods: Thirty questions concerning the diagnosis and treatment of hip and knee PJIs, stratified by a priori established difficulty, were generated by a team of experts, and administered to ChatGPT 3.5, BingChat, and ChatGPT 4.0. Responses were rated by three orthopedic surgeons and two infectious diseases physicians using a five-point Likert-like scale with numerical values to quantify the quality of responses. Inter-rater reliability was assessed by interclass correlation statistics.

Results: Responses averaged "good-to-very good" for all chatbots examined, both in diagnosis and treatment, with no significant differences according to the difficulty of the questions. However, BingChat ratings were significantly lower in the treatment setting (p = 0.025), particularly in terms of accuracy (p = 0.02) and completeness (p = 0.004). Agreement in ratings among examiners appeared to be very poor.

Conclusions: On average, the quality of responses is rated positively by experts, but with ratings that frequently may vary widely. This currently suggests that AI chatbot tools are still unreliable in the management of PJI.

背景:人工智能聊天机器人工具的回复可能会辨别出人类无法观察到的模式和相关性,从而进行更准确、更及时的干预。然而,它们回答医疗保健相关问题的可靠性仍存在争议。本研究旨在评估三个版本的基于 GPT 的人工关节感染(PJI)聊天机器人的性能:由一个专家团队生成了 30 个有关髋关节和膝关节假体关节感染的诊断和治疗的问题,这些问题按事先确定的难度进行了分层,并在 ChatGPT 3.5、BingChat 和 ChatGPT 4.0 上进行了测试。三位骨科医生和两位传染病医生采用五点李克特量表对回答进行评分,并用数值量化回答的质量。评分者之间的可靠性通过类间相关统计进行评估:结果:在诊断和治疗方面,所有接受检查的聊天机器人的平均回复质量均为 "好到非常好",与问题的难度没有明显差异。但是,BingChat 在治疗方面的评分明显较低(p = 0.025),尤其是在准确性(p = 0.02)和完整性(p = 0.004)方面。检查人员之间的评分一致性似乎很差:平均而言,专家对回复质量的评价是正面的,但评分经常会有很大差异。目前这表明,人工智能聊天机器人工具在PJI管理方面仍不可靠。
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引用次数: 0
To cast or not to cast? Postoperative care of ankle fractures: a meta-analysis of randomized controlled trials. 打石膏还是不打石膏?踝关节骨折术后护理:随机对照试验荟萃分析。
Q1 Medicine Pub Date : 2024-12-01 Epub Date: 2024-05-28 DOI: 10.1007/s12306-024-00832-2
F Barile, E Artioli, A Mazzotti, A Arceri, S O Zielli, M Manzetti, G Viroli, A Ruffilli, C Faldini

Postoperative care of ankle fractures treated with open reduction and internal fixation (ORIF) is a debated topic. A meta-analysis of Randomized Controlled Trials was conducted with the aim of comparing early mobilization and weightbearing to traditional postoperative protocols. A systematic search of electronic databases was conducted according to the PRISMA guidelines. Only randomized clinical trials were included. Data about clinical outcome, time to return to work and complications were extracted and summarized. Meta-analyses were performed. Twenty studies for a total of 1328 patients were included. Early mobilization was compared to immobilization in 724 patients: the two groups did not significantly differ in terms of short- and long-term clinical outcome (p = 0.08 and p = 0.41, respectively). However, early mobilization resulted to be significantly associated with faster return to work (p = 0.047). Early weightbearing was compared to nonweightbearing in 1088 patients. While the clinical difference between the two groups was not significant at short term (p = 0.08), it was significant at long term (p = 0.002). No other significant differences, in particular regarding complications, were highlighted between different groups. Early motion, early weightbearing and traditional postoperative protocols are all safe strategies after ORIF for unstable ankle fractures. Early mobilization is significantly associated with faster return to work and early weightbearing improves long term clinical outcome.Level of evidence: I.

采用开放复位内固定术(ORIF)治疗踝关节骨折的术后护理是一个备受争议的话题。我们对随机对照试验进行了荟萃分析,旨在比较早期活动和负重与传统术后方案。根据 PRISMA 指南对电子数据库进行了系统检索。只纳入了随机临床试验。提取并总结了有关临床结果、恢复工作时间和并发症的数据。进行了元分析。共纳入了 20 项研究,涉及 1328 名患者。对724名患者进行了早期动员与固定治疗的比较:两组患者的短期和长期临床疗效没有显著差异(分别为P = 0.08和P = 0.41)。不过,早期活动与更快地重返工作岗位明显相关(p = 0.047)。对1088名患者进行了早期负重与不负重的比较。虽然两组患者的短期临床差异不明显(p = 0.08),但长期差异明显(p = 0.002)。各组之间没有其他明显差异,尤其是在并发症方面。早期活动、早期负重和传统术后方案都是不稳定踝关节骨折 ORIF 术后的安全策略。早期活动与更快恢复工作密切相关,早期负重可改善长期临床效果:I.
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引用次数: 0
Necrotising fasciitis of the upper limb: a review of the literature. 上肢坏死性筋膜炎:文献综述。
Q1 Medicine Pub Date : 2024-12-01 Epub Date: 2024-07-02 DOI: 10.1007/s12306-024-00843-z
L Hainsworth, A Vaughan, N Picardo, A T Gough

Necrotising fasciitis is an uncommon life-threatening surgical emergency. While most commonly seen in the lower limb it can also affect the upper limb. This article reviews and summarises the current literature on necrotising fasciitis in the upper limb, covering common predisposing factors, clinical presentations, scoring systems, common organism types and the timing of surgical treatment. The key to managing this condition continues to be early clinical diagnosis and aggressive surgical debridement to attempt to reduce the morbidity and mortality of this condition.

坏死性筋膜炎是一种不常见的危及生命的外科急症。虽然最常见于下肢,但也可影响上肢。本文回顾并总结了目前有关上肢坏死性筋膜炎的文献,内容包括常见的易感因素、临床表现、评分系统、常见的机体类型以及手术治疗的时机。治疗这种疾病的关键仍然是早期临床诊断和积极的手术清创,以降低这种疾病的发病率和死亡率。
{"title":"Necrotising fasciitis of the upper limb: a review of the literature.","authors":"L Hainsworth, A Vaughan, N Picardo, A T Gough","doi":"10.1007/s12306-024-00843-z","DOIUrl":"10.1007/s12306-024-00843-z","url":null,"abstract":"<p><p>Necrotising fasciitis is an uncommon life-threatening surgical emergency. While most commonly seen in the lower limb it can also affect the upper limb. This article reviews and summarises the current literature on necrotising fasciitis in the upper limb, covering common predisposing factors, clinical presentations, scoring systems, common organism types and the timing of surgical treatment. The key to managing this condition continues to be early clinical diagnosis and aggressive surgical debridement to attempt to reduce the morbidity and mortality of this condition.</p>","PeriodicalId":18875,"journal":{"name":"MUSCULOSKELETAL SURGERY","volume":" ","pages":"377-381"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141492682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in retrograde techniques for osteochondral lesions: is there a different path we can take? 骨软骨病变逆行技术的进展:我们是否可以另辟蹊径?
Q1 Medicine Pub Date : 2024-12-01 Epub Date: 2024-11-15 DOI: 10.1007/s12306-024-00872-8
C Faldini
{"title":"Advances in retrograde techniques for osteochondral lesions: is there a different path we can take?","authors":"C Faldini","doi":"10.1007/s12306-024-00872-8","DOIUrl":"10.1007/s12306-024-00872-8","url":null,"abstract":"","PeriodicalId":18875,"journal":{"name":"MUSCULOSKELETAL SURGERY","volume":" ","pages":"373-375"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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MUSCULOSKELETAL SURGERY
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