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Application of Music Therapy in Improving Sleep Quality and Psychological Health of Pregnant Women with Hypertension: A Retrospective Study. 应用音乐疗法改善高血压孕妇的睡眠质量和心理健康:一项回顾性研究。
IF 1.3 4区 医学 Q3 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.4103/nah.nah_58_24
Yun Rong, Jingwen Jiang, Xueling Zhang, Yuntao Bu

Objective: The aim of the study was to retrospectively study the effect of music therapy on sleep quality and mental health level of pregnant women with hypertension in pregnancy (HIP).

Methods: A total of 188 pregnant women with gestational hypertension admitted to The Fourth Hospital of Shijiazhuang from January 2022 to January 2023 were selected as the research objects. Based on various management methods documented in the medical record system, the individuals were divided into a control group (n = 88, routine management) and an observation group (n = 100, routine management + music therapy). The State-Trait Anxiety Inventory (STAI), Athens Insomnia Scale (AIS), and pregnancy outcomes were compared between the two groups.

Results: No significant difference in the STAI and AIS scores before treatment was found between the two groups on admission (P > 0.05). The AIS and STAI scores in the observation group were lower than those in the control group 2 days after delivery (P < 0.05). The total incidence of adverse pregnancy outcomes in the observation group (8.00%) was lower than that in the control group (11.37%), but no significant difference between the two groups (P > 0.05).

Conclusions: The implementation of music therapy for patients with HIP can alleviate their negative emotions to a certain extent and can improve sleep, offering certain clinical promotion value.

研究目的该研究旨在回顾性研究音乐疗法对妊娠高血压(HIP)孕妇睡眠质量和心理健康水平的影响:选取 2022 年 1 月至 2023 年 1 月石家庄市第四医院收治的妊娠高血压孕妇共 188 名作为研究对象。根据病历系统中记录的各种管理方法,将其分为对照组(n=88,常规管理)和观察组(n=100,常规管理+音乐疗法)。对两组患者的状态-特质焦虑量表(STAI)、雅典失眠量表(AIS)和妊娠结果进行比较:入院时,两组患者在治疗前的 STAI 和 AIS 分数无明显差异(P > 0.05)。分娩 2 天后,观察组的 AIS 和 STAI 评分低于对照组(P < 0.05)。观察组不良妊娠结局的总发生率(8.00%)低于对照组(11.37%),但两组间无显著差异(P > 0.05):对HIP患者实施音乐疗法,可在一定程度上缓解其不良情绪,改善睡眠,具有一定的临床推广价值。
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引用次数: 0
Analysis of Therapeutic Options for Noise-Induced Hearing Loss: Retroauricular Injection of Methylprednisolone Sodium Succinate Combined with Hyperbaric Oxygenation. 噪声性听力损失的治疗方案分析:耳后注射甲泼尼龙琥珀酸钠与高压氧相结合。
IF 1.3 4区 医学 Q3 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.4103/nah.nah_60_24
Yan Yao, Lei Li

Objective: To evaluate the clinical effect of retroaural injection of methylprednisolone sodium succinate combined with hyperbaric oxygen (HBO) on the treatment of noise-induced hearing loss.

Methods: Case data of 220 patients with hearing loss treated at the Zhongda Hospital Southeast University from January 1, 2019 to August 1, 2023 were obtained. As per the treatment plan, the recruited patients were divided into two cohorts: 158 cases in the combined-treatment group (retroaural injection of methylprednisolone sodium succinate combined with HBO) and 62 cases in the single-hormone group (retroaural injection of methylprednisolone sodium succinate). Comparison of the clinical efficacies and postoperative complication rates of the two groups was performed after treatment. MS-Excel was used to build a database for all data, and SPSS26.0 was utilized in the statistical analysis of recorded data.

Results: For patients with low-frequency, high-frequency, and flat descending type, the combined-treatment group showed significantly higher clinical effective rate than the single-hormone group (P < 0.05). For patients with disease duration ≤7 days, the combined-treatment group attained a significantly higher clinical effective rate was than the single-hormone group (P < 0.05). The safety of patients in both groups was evaluated mainly through their adverse reactions. The total incidence of adverse reactions in the single-hormone group reached 9.68%, and that in the combined-treatment group was 8.23%. The two groups revealed no significant difference in terms of incidence of adverse reactions (P > 0.05).

Conclusion: HBO combined with retroaural injection of methylprednisolone sodium succinate has good clinical efficacy and safety in the treatment of hearing loss.

目的评价耳后注射甲泼尼龙琥珀酸钠联合高压氧(HBO)治疗噪声性听力损失的临床效果:获取2019年1月1日至2023年8月1日东南大学附属中大医院收治的220例听力损失患者的病例资料。根据治疗方案,将入选患者分为两组:联合治疗组(耳后注射甲泼尼龙琥珀酸钠联合HBO)158例,单一激素组(耳后注射甲泼尼龙琥珀酸钠)62例。治疗后对两组的临床疗效和术后并发症发生率进行了比较。使用 MS-Excel 为所有数据建立数据库,并使用 SPSS26.0 对记录的数据进行统计分析:对于低频型、高频型和平降型患者,联合治疗组的临床有效率明显高于单一激素组(P<0.05)。对于病程≤7天的患者,联合治疗组的临床有效率明显高于单一激素组(P<0.05)。两组患者的安全性主要通过其不良反应进行评估。单一激素组的不良反应总发生率为 9.68%,联合治疗组为 8.23%。两组不良反应发生率无明显差异(P>0.05):结论:HBO 联合耳后注射甲泼尼龙琥珀酸钠治疗听力损失具有良好的临床疗效和安全性。
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引用次数: 0
Effects of Five-Element Music Stimulation in Perioperative Period on Sleep Status and Psychological Regulation in Patients Undergoing Orthopedic Surgery. 围术期五元素音乐刺激对骨科手术患者睡眠状态和心理调节的影响
IF 1.3 4区 医学 Q3 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.4103/nah.nah_77_24
Zhihui Ren, Yanwen Xue

Objective: This study aimed to explore the effect of five-element music therapy on sleep status during perioperative period and psychological regulation in patients undergoing orthopedic surgery.

Methods: The medical records of patients who underwent orthopedic surgery from March 2021 to December 2023 in the Gansu Provincial Hospital of Traditional Chinese Medicine were retrospectively analyzed. Patients were divided into two groups in accordance with the nursing time period. The control group (88 patients) received routine nursing, and the observation group (78 patients) received five-element music management in the perioperative period based on routine nursing. The management time was from admission to one week after surgery, with 30 min/times, TID. The sleep, physical signs, pain condition, and anxiety status of the two groups were compared on admission, before surgery, and one week after surgery.

Results: On admission, no significant difference in the scores of the Pittsburgh Sleep Quality Index (PSQI), the pain rating index (PRI), and the Self-Rating Anxiety Scale (SAS) was found between the two groups (P > 0.05). Before and one week after surgery, the PSQI, PRI, and SAS scores of the observation group were significantly lower than those of the control group (P < 0.001). No significant difference was found in systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) between the two groups on admission and one week after surgery (P > 0.05). Before surgery, the observation group had significantly lower indices of SBP, DBP, and HR than the control group (P < 0.05).

Conclusion: Five-element music stimulation in the perioperative period can improve the pain and anxiety of patients undergoing orthopedic surgery and enhance their sleep status.

目的本研究旨在探讨五行音乐疗法对骨科手术患者围手术期睡眠状态及心理调节的影响:回顾性分析甘肃省中医院 2021 年 3 月至 2023 年 12 月骨科手术患者的病历。按照护理时间段将患者分为两组。对照组(88 例)接受常规护理,观察组(78 例)在常规护理基础上进行围手术期五行音乐管理。管理时间为入院至术后一周,30 分钟/次,TID。比较两组患者入院时、术前和术后一周的睡眠、体征、疼痛状况和焦虑状态:入院时,两组患者的匹兹堡睡眠质量指数(PSQI)、疼痛评分指数(PRI)和焦虑自评量表(SAS)得分无明显差异(P>0.05)。术前和术后一周,观察组的 PSQI、PRI 和 SAS 评分明显低于对照组(P < 0.001)。两组入院时和术后一周的收缩压(SBP)、舒张压(DBP)和心率(HR)无明显差异(P > 0.05)。手术前,观察组的 SBP、DBP 和 HR 指数明显低于对照组(P < 0.05):结论:围手术期的五元素音乐刺激可改善骨科手术患者的疼痛和焦虑,并提高其睡眠质量。
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引用次数: 0
Effect of Comprehensive Noise Reduction Management on the Postoperative Negative Emotion, Stress Response Hormone and Sleep Status of Burn Patients: Single-Centre Retrospective Analysis. 综合降噪管理对烧伤患者术后负面情绪、应激反应激素和睡眠状态的影响:单中心回顾性分析。
IF 1.3 4区 医学 Q3 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.4103/nah.nah_80_24
Zhuo Dai, Xiaojiao Cheng, Fang Chen

Objective: This study aimed to explore the effect of comprehensive noise reduction management on the postoperative recovery of burn patients.

Methods: Data of 156 patients admitted to Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University from October 2022 to July 2023 were retrospectively analysed. The patients were divided into two groups according to the management method: group A (n = 76, standard care of burns) and group B (n = 80, standard care of burns+comprehensive noise reduction management). The stress response level, anxiety and depression level, sleep quality and satisfaction of the two groups were compared before and after the management.

Results: Before the management, no statistically significant differences in cortisol (Cor), anxiety and depression scores and sleep quality were found between the two groups (P > 0.05). After the management, significant differences in Cor, anxiety scores, sleep quality and patient satisfaction were observed between the two groups (P < 0.001).

Conclusions: Comprehensive noise reduction management can reduce postoperative stress hormone levels, alleviate negative emotions, such as anxiety, and improve sleep quality and patient satisfaction.

目的:本研究旨在探讨综合降噪管理对烧伤患者术后恢复的影响:本研究旨在探讨综合降噪管理对烧伤患者术后恢复的影响:回顾性分析南京大学医学院附属金陵医院2022年10月至2023年7月收治的156例烧伤患者的资料。根据管理方法将患者分为两组:A组(n=76,烧伤标准护理)和B组(n=80,烧伤标准护理+综合降噪管理)。比较两组患者在管理前后的应激反应水平、焦虑和抑郁水平、睡眠质量和满意度:结果:管理前,两组患者的皮质醇(Cor)、焦虑和抑郁评分以及睡眠质量差异无统计学意义(P > 0.05);管理后,两组患者的皮质醇(Cor)、焦虑和抑郁评分以及睡眠质量差异有统计学意义(P > 0.05)。管理后,两组患者在皮质醇(Cor)、焦虑评分、睡眠质量和患者满意度方面有明显差异(P < 0.001):综合降噪管理可降低术后应激激素水平,缓解焦虑等负面情绪,提高睡眠质量和患者满意度。
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引用次数: 0
Effect of Noise Management in Interventional Radiology Suites on Patients Undergoing Transarterial Chemoembolization: A Retrospective Study. 介入放射科手术室噪音管理对经动脉化疗栓塞术患者的影响:回顾性研究。
IF 1.3 4区 医学 Q3 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.4103/nah.nah_53_24
Yong Lu, Lingyu Ma, Zhuo Chen, Hui Qi, Zhaotian Gu, Lei Wu, Benfang Fan

Objective: This study aims to evaluate the effect of noise management in interventional radiology suites on patients undergoing transarterial chemoembolization (TACE).

Methods: A retrospective cohort study design was employed. The study included a total of 141 patients with hepatocellular carcinoma who underwent TACE surgery in interventional radiology suite of the First People's Hospital of Nantong from January 2022 to December 2022. The patients were divided into an observation group (received noise management, n = 70) and a control group (did not receive noise management, n = 71) on the basis of whether they received noise management. Patient demographics and surgical data were collected, and heart rate, blood pressure, and anxiety levels were assessed before, during and after surgery. Satisfaction and the incidence of adverse reactions were also documented.

Results: No significant differences were found in general characteristics. The comparison between the observation and control groups revealed statistically significant differences in noise levels (P < 0.001). Additionally, anxiety levels significantly differed between the two groups (P = 0.040) as well as across different time points (P < 0.001). However, no significant difference was found in the occurrence of adverse events between groups (P = 0.772). Furthermore, patient satisfaction was significantly higher in the observation group than that in the control group (P < 0.001). Although no significant differences were found in heart rate and systolic blood pressure between groups (P > 0.05), and a significant main effect of time was observed for both variables (P < 0.001).

Conclusion: Noise management in the interventional radiology suite effectively alleviates intraoperative anxiety among patients with TACE and improves treatment satisfaction but has no significant effect on physiological changes and the incidence of adverse events.

研究目的本研究旨在评估介入放射科手术室噪音管理对接受经动脉化疗栓塞术(TACE)患者的影响:采用回顾性队列研究设计。研究对象包括2022年1月至2022年12月在南通市第一人民医院介入放射科接受TACE手术的肝细胞癌患者,共141例。根据是否接受噪音管理,将患者分为观察组(接受噪音管理,n = 70)和对照组(未接受噪音管理,n = 71)。研究人员收集了患者的人口统计数据和手术数据,并在手术前、手术中和手术后对患者的心率、血压和焦虑程度进行了评估。此外,还记录了满意度和不良反应的发生率:结果:总体特征无明显差异。观察组和对照组在噪音水平上有显著差异(P < 0.001)。此外,焦虑水平在两组之间(P = 0.040)以及不同时间点之间(P < 0.001)存在显著差异。然而,在不良事件发生率方面,两组之间没有发现明显差异(P = 0.772)。此外,观察组患者的满意度明显高于对照组(P < 0.001)。虽然各组之间的心率和收缩压没有发现明显差异(P > 0.05),但两个变量都观察到了明显的时间主效应(P < 0.001):结论:介入放射室的噪音管理可有效缓解 TACE 患者的术中焦虑,提高治疗满意度,但对生理变化和不良事件的发生率无明显影响。
{"title":"Effect of Noise Management in Interventional Radiology Suites on Patients Undergoing Transarterial Chemoembolization: A Retrospective Study.","authors":"Yong Lu, Lingyu Ma, Zhuo Chen, Hui Qi, Zhaotian Gu, Lei Wu, Benfang Fan","doi":"10.4103/nah.nah_53_24","DOIUrl":"10.4103/nah.nah_53_24","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to evaluate the effect of noise management in interventional radiology suites on patients undergoing transarterial chemoembolization (TACE).</p><p><strong>Methods: </strong>A retrospective cohort study design was employed. The study included a total of 141 patients with hepatocellular carcinoma who underwent TACE surgery in interventional radiology suite of the First People's Hospital of Nantong from January 2022 to December 2022. The patients were divided into an observation group (received noise management, n = 70) and a control group (did not receive noise management, n = 71) on the basis of whether they received noise management. Patient demographics and surgical data were collected, and heart rate, blood pressure, and anxiety levels were assessed before, during and after surgery. Satisfaction and the incidence of adverse reactions were also documented.</p><p><strong>Results: </strong>No significant differences were found in general characteristics. The comparison between the observation and control groups revealed statistically significant differences in noise levels (P < 0.001). Additionally, anxiety levels significantly differed between the two groups (P = 0.040) as well as across different time points (P < 0.001). However, no significant difference was found in the occurrence of adverse events between groups (P = 0.772). Furthermore, patient satisfaction was significantly higher in the observation group than that in the control group (P < 0.001). Although no significant differences were found in heart rate and systolic blood pressure between groups (P > 0.05), and a significant main effect of time was observed for both variables (P < 0.001).</p><p><strong>Conclusion: </strong>Noise management in the interventional radiology suite effectively alleviates intraoperative anxiety among patients with TACE and improves treatment satisfaction but has no significant effect on physiological changes and the incidence of adverse events.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 122","pages":"325-331"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11540005/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142350874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the Therapeutic Effectiveness of Music Therapy in Post-Laparoscopic Ovarian Cystectomy Patients: A Single-Center Retrospective Study. 评估音乐疗法对腹腔镜卵巢囊肿切除术后患者的治疗效果:单中心回顾性研究
IF 1.3 4区 医学 Q3 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.4103/nah.nah_120_23
Feng Wang, Hui Fu

Background: The therapeutic effects of music therapy on improving negative emotions and reducing pain are increasingly acknowledged. However, limited clinical research exists on its use in patients post-laparoscopic ovarian cystectomy (LOC).

Materials and methods: A total of 147 patients undergoing LOC at our hospital were evaluated. Patients were divided based on the implementation time of music therapy: group A (72 patients, October 2020 to October 2021) received standard clinical treatment, while group B (75 patients, November 2021 to November 2022) received music therapy alongside routine care. The baseline data of patients and the scores of the Short-Form McGill Pain Questionnaire (SF-MPQ), Perceived Stress Scale (PSS), Beck Anxiety Inventory (BAI), and Patient Satisfaction Questionnaire were collected. Pain and psychological stress levels were compared on the first postoperative day and at discharge to assess the clinical value of each treatment approach.

Results: Group B exhibited significantly lower PSS, SF-MPQ, and BAI scores (P < 0.001 for all) and higher overall satisfaction at discharge (P < 0.001). These findings suggest that music therapy can reduce psychological stress, decrease pain levels, and improve mood in patients undergoing LOC.

Conclusion: This study demonstrates that music therapy positively rehabilitates patients after LOC, offering new insights for future clinical treatment strategies.

背景:音乐疗法在改善负面情绪和减轻疼痛方面的治疗效果日益得到认可。然而,关于音乐疗法在腹腔镜卵巢囊肿切除术(LOC)术后患者中应用的临床研究还很有限:对本院接受腹腔镜卵巢囊肿切除术的 147 名患者进行了评估。根据音乐治疗的实施时间将患者分为两组:A 组(72 名患者,2020 年 10 月至 2021 年 10 月)接受标准临床治疗,B 组(75 名患者,2021 年 11 月至 2022 年 11 月)在常规护理的同时接受音乐治疗。收集了患者的基线数据以及短式麦吉尔疼痛问卷(SF-MPQ)、知觉压力量表(PSS)、贝克焦虑量表(BAI)和患者满意度问卷的得分。比较术后第一天和出院时的疼痛和心理压力水平,以评估每种治疗方法的临床价值:结果:B 组患者的 PSS、SF-MPQ 和 BAI 评分明显较低(P < 0.001),出院时的总体满意度较高(P < 0.001)。这些结果表明,音乐疗法可以减轻 LOC 患者的心理压力、降低疼痛程度并改善情绪:本研究表明,音乐疗法能积极促进 LOC 患者的康复,为未来的临床治疗策略提供了新的思路。
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引用次数: 0
Gastrodin Ameliorates Learning and Memory Impairments Caused by Long-Term Noise Exposure. 天麻素能改善长期暴露于噪音环境造成的学习和记忆障碍
IF 1.3 4区 医学 Q3 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.4103/nah.nah_76_24
Lin Wu, Ying Liu, Hu Zhou, Zhenzhen Cao, Jianyun Yu

The developing brain is significantly affected by long-term exposure to noise at an early age, leading to functional disorders such as learning and memory impairments. Gastrodin (GAS), a natural organic compound, is an extraction of phenolic glycoside from the rhizome of Gastrodia elata. Clinically, GAS is extensively utilised for the treatment of neurological disorders. This study aimed to explore the effect and mechanism of GAS on noise exposure-induced learning and memory impairments. Rats aged 21 days were exposed to a 90 dB noise environment for 4 weeks and divided into the noise group, the noise + GAS group, and the control group to establish a noise exposure model. After noise exposure treatment, the improvement effect of GAS on the memory of rats was evaluated by Y-maze and Morris water maze. Enzyme-linked immunosorbent assay was utilised to determine the effect of GAS on neurotransmitter levels in the hippocampal tissue of noise-exposed rats. Western blot was applied for the detection of the protein levels of neurotrophic factors. The GAS treatment significantly improved spatial memory and increased the levels of key neurotransmitters (norepinephrine, dopamine and serotonin) and neurotrophic factors (neurotrophin-3 and brain-derived neurotrophic factor) in the hippocampal tissues of noise-exposed rats. These alterations correlate with enhanced cognitive functions, suggesting a neuroprotective effect of GAS against noise-induced cognitive impairments. This study supports the potential of GAS to treat noise-induced learning and memory impairments by modulating neurotransmitter secretion and enhancing the expression levels of neurotrophic factors. These findings offer potential therapeutic avenues for cognitive impairments induced by noise exposure.

发育中的大脑在幼年时期长期暴露于噪音中会受到严重影响,导致学习和记忆障碍等功能紊乱。天麻素(GAS)是一种天然有机化合物,是从天麻根茎中提取的酚苷。在临床上,天麻素被广泛用于治疗神经系统疾病。本研究旨在探讨天麻素对噪音暴露引起的学习和记忆障碍的影响和机制。将年龄为 21 天的大鼠暴露在 90 dB 的噪音环境中 4 周,并将其分为噪音组、噪音 + GAS 组和对照组,以建立噪音暴露模型。噪音暴露处理后,通过Y迷宫和Morris水迷宫评估GAS对大鼠记忆力的改善作用。利用酶联免疫吸附法测定 GAS 对噪声暴露大鼠海马组织中神经递质水平的影响。Western 印迹法用于检测神经营养因子的蛋白水平。经 GAS 治疗后,噪声暴露大鼠海马组织中的空间记忆明显改善,关键神经递质(去甲肾上腺素、多巴胺和血清素)和神经营养因子(神经营养素-3 和脑源性神经营养因子)的水平也有所提高。这些变化与认知功能的增强相关,表明 GAS 对噪声引起的认知障碍具有神经保护作用。这项研究支持 GAS 通过调节神经递质分泌和提高神经营养因子的表达水平来治疗噪声引起的学习和记忆损伤的潜力。这些发现为治疗噪声暴露引起的认知障碍提供了潜在的治疗途径。
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引用次数: 0
Noise is a Risk Factor for Patients with Ulcerative Colitis and Anxiety. 噪音是溃疡性结肠炎和焦虑症患者的一个风险因素。
IF 1.3 4区 医学 Q3 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.4103/nah.nah_51_24
Jiao Zhu, Xiaoyang Ren, Shuixiang He, Chen Mi, Li Zhang, Dan Zhou, Miaosha Luo

Background: This work aimed to explore anxiety-associated risk factors in patients diagnosed with ulcerative colitis (UC).

Methods: Clinical data from patients diagnosed with UC and hospitalized at the First Affiliated Hospital of Xi'an Jiaotong University between May 2019 and June 2022 were retrospectively analyzed. A total of 260 patients were included and divided into UC with anxiety (n = 86) and UC without anxiety (n = 174) groups according to the Self-Rating Anxiety Scale score. The quality of life and disease activity in patients with UC were assessed using the Inflammatory Bowel Disease Questionnaire and Mayo Score, respectively. Clinical data, disease characteristics, quality of life, disease activity, and noise exposure were compared between the groups, and factors contributing to anxiety in patients with UC were explored through multivariate logistic regression analysis.

Results: No significant difference was found between the groups in terms of disease duration (P = 0.73), distribution of disease (P = 0.86), or medication use (P = 0.86). However, compared to UC patients without anxiety, those with anxiety were older (P < 0.05), predominantly female (P < 0.05), had lower quality of life (P < 0.05), experienced higher disease activity (P < 0.05), and had greater noise exposure (P < 0.05). The quality of life [odds ratio (OR) = 0.558, 95% confidence interval (CI) = 0.348-0.895, P = 0.02] was a protective factor for anxiety in patients with UC. Disease activity (OR = 1.680, 95% CI = 1.103-2.561, P = 0.02) and noise exposure (OR = 2.148, 95% CI = 1.084-4.106, P = 0.01) were significant risk factors for anxiety in patients with UC.

Conclusion: Noise exposure and disease activity were associated with an increased risk of anxiety in patients with UC, whereas higher quality of life was protective against anxiety in UC patients.

背景:这项研究旨在探讨溃疡性结肠炎(UC)患者的焦虑相关风险因素:本研究旨在探讨溃疡性结肠炎(UC)患者的焦虑相关风险因素:回顾性分析了2019年5月至2022年6月期间在西安交通大学第一附属医院住院的确诊为UC的患者的临床数据。共纳入260名患者,根据焦虑自评量表评分分为UC伴焦虑组(n = 86)和UC无焦虑组(n = 174)。UC 患者的生活质量和疾病活动性分别通过炎症性肠病问卷和梅奥评分进行评估。比较了各组之间的临床数据、疾病特征、生活质量、疾病活动性和噪音暴露情况,并通过多变量逻辑回归分析探讨了导致 UC 患者焦虑的因素:结果:两组患者在病程(P = 0.73)、疾病分布(P = 0.86)或药物使用(P = 0.86)方面无明显差异。然而,与没有焦虑症的 UC 患者相比,有焦虑症的患者年龄更大(P < 0.05),以女性为主(P < 0.05),生活质量更低(P < 0.05),疾病活动性更高(P < 0.05),接触的噪音更大(P < 0.05)。生活质量[几率比(OR)= 0.558,95% 置信区间(CI)= 0.348-0.895,P = 0.02]是 UC 患者焦虑的保护因素。疾病活动(OR = 1.680,95% CI = 1.103-2.561,P = 0.02)和噪音暴露(OR = 2.148,95% CI = 1.084-4.106,P = 0.01)是导致 UC 患者焦虑的重要危险因素:结论:噪声暴露和疾病活动与 UC 患者焦虑风险的增加有关,而较高的生活质量对 UC 患者的焦虑具有保护作用。
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引用次数: 0
Noise Exposure Promotes Alzheimer's Disease-Like Lesions and DNA Damage. 噪音会促进阿尔茨海默病样病变和 DNA 损伤
IF 1.3 4区 医学 Q3 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.4103/nah.nah_26_24
Xiao-Jie Dai, Jun-Hua Liao, Yi Jia, Rui Cao, Mei-Ning Zhou

Objective: This study aimed to explore the mechanism by which noise contributes to the development of Alzheimer's disease (AD)-like lesions.

Method: Male Wistar rats (24 months) were allocated into two groups (n = 6 per groups): a noise group exposed to 98 dB sound pressure-level white noise for 4 hours daily from 8:00 to 12:00 for 30 days, and a control group without noise exposure. The cognitive functions of the rats were assessed using new-object recognition and Morris water maze tests. Then, hippocampal tissues were collected, and the levels of amyloid β 1-42 (Aβ1-42), Aβ1-40, brain-derived neurotrophic factor (BDNF), and tropomyosin receptor kinase B (TrkB) were measured using enzyme-linked immunosorbent assay (ELISA). Protein expression was evaluated through Western blot.

Results: Noise exposure significantly impaired cognitive and recognition abilities, increased the escape latency, and decreased the number of crossings through the platform quadrant intersection and the time spent in the target quadrant (P < 0.01). The new-object exploration and recognition index of the rats in the noise group markedly decreased (P < 0.01). ELISA results indicated increases in Aβ1-40 and Aβ1-42 levels and decreases in BDNF and TrkB levels in the rat hippocampus in the noise group (P < 0.01). Western blot analyses revealed that beta-site amyloid precursor protein (APP) cleaving enzyme 1, phosphorylated tau protein, gamma-H2A histone family, member X, checkpoint kinase 2, p53, and p21 were remarkably elevated in the noise group (P < 0.01).

Conclusion: Chronic noise exposure can cause hippocampal genetic damage in aged rats, leading to cognitive disorders and the development of lesions similar to those observed in AD. Thus, noise is a potential risk factor for neurodegenerative disorders.

研究目的本研究旨在探讨噪声导致阿尔茨海默病(AD)样病变发生的机制:将雄性Wistar大鼠(24个月)分为两组(每组6只):噪音组每天8:00至12:00暴露于98分贝声压级的白噪音中4小时,为期30天;对照组不暴露于噪音。通过新物体识别和莫里斯水迷宫测试评估大鼠的认知功能。然后收集海马组织,并使用酶联免疫吸附试验(ELISA)测定淀粉样β 1-42(Aβ1-42)、Aβ1-40、脑源性神经营养因子(BDNF)和肌球蛋白受体激酶B(TrkB)的水平。蛋白质表达通过 Western 印迹进行评估:结果:暴露于噪声会明显损害认知和识别能力,增加逃逸潜伏期,减少穿越平台象限交叉点的次数和在目标象限停留的时间(P < 0.01)。噪音组大鼠的新物体探索和识别指数明显下降(P < 0.01)。ELISA结果显示,噪音组大鼠海马中Aβ1-40和Aβ1-42水平升高,BDNF和TrkB水平降低(P < 0.01)。Western印迹分析显示,噪声组大鼠海马中β位淀粉样前体蛋白(APP)裂解酶1、磷酸化tau蛋白、γ-H2A组蛋白家族成员X、检查点激酶2、p53和p21显著升高(P < 0.01):结论:长期暴露于噪声可导致老年大鼠海马基因损伤,从而导致认知障碍,并出现类似于老年痴呆症的病变。因此,噪声是神经退行性疾病的潜在风险因素。
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引用次数: 0
Assessment of Noise Exposure and Risk of Hearing Loss for Young People in Amusement Arcades. 游乐场噪音暴露和青少年听力损失风险评估。
IF 1.3 4区 医学 Q3 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.4103/nah.nah_59_23
Nengsong Zou, Hongwei Wang, Zhixuan Huang, Qiaochu Wang

Background: Amusement arcades are one of the most popular entertainment venues for young people, but excessive noise levels inside them could harm young people's hearing. The aim of this study is to assess the characteristics and risk of noise exposure for young people in amusement arcades and understand their knowledge of and attitudes towards safe listening.

Methods: In this study, noise measurement was conducted in five large amusement arcades to collect 40 noise samples. At the same time, questionnaires were used in each amusement arcade to investigate young players' social information, subjective perception, and cognition of noise-induced hearing loss (NIHL).

Results: The level of the noise samples ranged from 83.05 to 89.4 dBA. There are significant differences in noise levels between amusement arcades (P < 0.05), but there is no significant difference in noise levels between different games (P > 0.05). The subjective questionnaire survey shows that 61.9% of young people feel that the sound of video games is noisy or very noisy, but it is worth noting that 63.5% of them do not know or think that noise will not cause hearing loss, and 39.7% of people will choose to do nothing to help them endure the noise in such an environment. For safe listening, young people are more inclined to choose measures to stay in quiet areas and reduce the volume of game devices.

Conclusions: The noise levels in most amusement arcades have exceeded the exposure limits recommended by the Environment Protection Agency (EPA); subjective questionnaires also indicate that internal noise levels may cause hearing loss, and young customers did not know enough about safe listening. For young people's hearing safety, these issues need more attention.

背景:游乐场是最受年轻人欢迎的娱乐场所之一,但游乐场内的噪音过大可能会损害年轻人的听力。本研究旨在评估青少年在游乐场内接触噪声的特点和风险,并了解他们对安全倾听的认识和态度:本研究在五家大型游乐场进行噪音测量,收集了40个噪音样本。方法:本研究在五家大型游乐场进行噪声测量,共采集了40个噪声样本,同时在每家游乐场进行问卷调查,以了解青少年玩家的社会信息、主观感受以及对噪声性听力损失(NIHL)的认知情况:结果:噪声样本的水平在 83.05 至 89.4 dBA 之间。不同游戏厅之间的噪音水平存在明显差异(P < 0.05),但不同游戏之间的噪音水平没有明显差异(P > 0.05)。主观问卷调查显示,61.9%的青少年觉得电子游戏机的声音很吵或非常吵,但值得注意的是,63.5%的人不知道或认为噪音不会导致听力损失,39.7%的人会选择在这样的环境中不采取任何措施来帮助自己忍受噪音。为了安全倾听,年轻人更倾向于选择待在安静的区域和降低游戏设备音量的措施:结论:大多数电玩城的噪音水平已经超过了美国环保署(EPA)建议的暴露限值;主观问卷调查也表明,内部噪音水平可能会导致听力损失,而且年轻顾客对安全倾听的认识不足。为了青少年的听力安全,这些问题需要得到更多关注。
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引用次数: 0
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Noise & Health
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