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Implementing real-time sepsis alerts using middleware and smartphone technology 使用中间件和智能手机技术实现实时败血症警报
Q4 Nursing Pub Date : 2020-03-01 DOI: 10.1097/01.CCN.0000654832.34404.99
M. Zimmermann, You “Jay” Chung, Cara Fleming, Jericho Garcia, Yekaterina Tayban, H. J. Alvarez, MaryAnn Connor
A s clinical practice continues to evolve and improve, technology has become increasingly integrated into everyday clinical workflow. From alarms and alerts to pointof-care electronic clinical communication tools, the future of healthcare depends on the ability to implement technology to improve quality and safety of patient care.1 Adoption of electronic health records (EHRs) has been found to improve clinicians’ performance by providing access to aggregated patient information such as lab results, nursing notes, and alerts.2 The use of decision support system technology, along with clinical reasoning, can help decrease errors and avoid delays in treatment.3 Real-time alerts and data to and from mobile platforms can lead to early diagnosis and detection, with the opportunity to improve quality of life and reduce healthcare costs.4 However, caution must be taken with these implementations to evaluate and address alert fatigue (often called alarm fatigue) and ensure alerts are clinically actionable and relevant.5 Development of alert algorithms through an EHR should help provide clinical decision support by supplying relevant information, at the time it is needed, to the correct clinician.6 An example of this includes the high-risk scenario of sepsis identification, with alerts triggered from the EHR. Research has shown that sepsis alerts can help improve patient outcomes by assisting with early detection.7,8 A study by Dziadzko and colleagues compared the emergence of smartphones for sepsis alerts to EHR-based notifications and pagers to determine the best method of notification delivery.6 Due to technologic failures and barriers, sepsis smartphone alerts were unsuccessful, and clinicians continued to use pagers and EHR-based alerts.6 Continued research and development were identified as needs to better evaluate the efficacy of smartphone alerts in a clinical setting.6 Since May 2013, the New York State Department of Health (NYSDOH) has regulated that hospitals maintain sepsis protocols that use explicit algorithms and/ or alert systems to assist in the early identification of patients with severe sepsis and septic shock.9,10 However, in January 2017, regulatory changes necessitated real-time, prospective identification of sepsis and standardized clinician documentation.11 This documentation was needed to record an initial assessment, and recognition of sepsis signs and symptoms as well as verifying reassessment of the patient’s sepsis signs and symptoms within 6 hours of management. At Memorial Sloan Kettering Cancer Center (MSKCC), the alert algorithm was initially set so that patients with three simultaneous abnormal vital signs, new (in a 24-hour period) altered mental status, or rigors in the presence of two abnormal vital signs triggered an alert. MSKCC has a unique population of oncology patients, and patient signs and symptoms or treatment adverse reactions could often be similar to sepsis indicators. Sepsis alerts were put in place to hel
随着临床实践的不断发展和改进,技术已越来越多地融入日常临床工作流程。从警报和警报到护理点电子临床通信工具,医疗保健的未来取决于实施技术以提高患者护理质量和安全性的能力,和警报。2决策支持系统技术的使用,以及临床推理,可以帮助减少错误,避免治疗延误。3移动平台之间的实时警报和数据可以导致早期诊断和检测,有机会提高生活质量,降低医疗成本。4然而,这些实施必须谨慎,以评估和解决警报疲劳(通常称为警报疲劳),并确保警报在临床上是可操作的和相关的。5通过EHR开发警报算法应有助于通过在需要时提供相关信息来提供临床决策支持,这方面的一个例子包括败血症识别的高风险场景,EHR会触发警报。研究表明,败血症警报可以通过协助早期检测来帮助改善患者的预后。7,8 Dziadzko及其同事的一项研究将败血症警报智能手机的出现与基于EHR的通知和寻呼机进行了比较,以确定最佳的通知传递方法。6由于技术故障和障碍,败血症智能手机警报没有成功,临床医生继续使用寻呼机和基于EHR的警报。6持续的研究和开发被确定为需要在临床环境中更好地评估智能手机警报的功效。6自2013年5月以来,纽约州卫生部(NYSDOH)已规定医院维持败血症协议,该协议使用明确的算法和/或警报系统来帮助早期识别严重败血症和感染性休克患者。9,10然而,2017年1月,监管变化需要实时、,脓毒症的前瞻性鉴定和标准化临床医生文件。11需要该文件来记录初步评估、对脓毒症体征和症状的识别,以及在治疗后6小时内验证对患者脓毒症症状和体征的重新评估。在纪念斯隆-凯特琳癌症中心(MSKCC),最初设置警报算法,使同时出现三种异常生命体征、新的(24小时内)精神状态改变或出现两种异常生命迹象的患者触发警报。MSKCC有一个独特的肿瘤患者群体,患者的体征和症状或治疗不良反应通常与败血症指标相似。设置败血症警报是为了帮助管理他们复杂的医疗需求,并帮助识别可能的早期败血症。根据记录生命体征/精神状态变化的人员,护士或患者护理技术人员随后通过EHR中的即时弹出窗口获得警报,联系负责的临床医生,对患者进行可能的败血症筛查。这导致临床医生对可能的败血症的认识延迟;其中,该算法是基于具有限制因素的护理文档工作流程设计的
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引用次数: 2
Reticulocyte count 网织红细胞计数
Q4 Nursing Pub Date : 2020-02-07 DOI: 10.32388/s5p8lj
Principle Using a supravital stain (e.g., new methylene blue), residual ribosomal RNA within the reticulocytes is precipitated. An equal volume of stain is added to EDTA-anticoagulated blood, the dilution mixture incubated, and a smear is prepared. The smear is examined to determine the number of reticulocytes present. An erythrocyte containing two or more particles of blue-stained material is a reticulocyte. The number of reticulocytes is expressed as a percentage of the total number of erythrocytes counted. 1
原理:使用活体染色(如新亚甲基蓝),沉淀网状细胞内残留的核糖体RNA。将等量的染色剂加入edta抗凝血中,将稀释混合物孵育,并制备涂片。检查涂片以确定网状红细胞的数量。含有两个或两个以上蓝色染色物质颗粒的红细胞称为网织红细胞。网织红细胞的数量以红细胞总数的百分比表示。1
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引用次数: 3
Do a surrogate decision-maker's motives matter? 代理决策者的动机重要吗?
Q4 Nursing Pub Date : 2020-02-01 DOI: 10.1097/01.CCN.0000718340.28170.d1
M. J. Deem, J. Stephen
When an adult patient lacks the capacity to make her or his own healthcare decisions, the clinical team turns to a surrogate decision-maker (typically a family member) to assist in making decisions that protect and promote the interests of the patient. However, requests by a surrogate that may not be in the patient’s best interest may make the clinical team uncomfortable. In this article, a bioethicist, Michael
当成年患者缺乏做出自己医疗保健决策的能力时,临床团队会求助于代理决策者(通常是家庭成员),以帮助做出保护和促进患者利益的决策。然而,代理人提出的可能不符合患者最佳利益的请求可能会让临床团队感到不舒服。在这篇文章中,生物伦理学家迈克尔
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引用次数: 1
International dissemination of evidence 证据的国际传播
Q4 Nursing Pub Date : 2020-01-01 DOI: 10.1097/01.CCN.0000612860.71342.d3
P. Conley
Achieving international dissemination of research findings involving critical care issues in nursing is essential to optimizing patient outcomes. Research evidence can impact the lives of individuals all over the world, but knowledge gaps exist due in part to lack of publication or presentation of research findings. Moher and colleagues reported that more than 50% of completed research findings are not published.1 This article discusses the need for global dissemination of research and outlines the steps researchers can take to publish their study results.
在国际上传播涉及重症护理问题的研究成果对于优化患者的治疗效果至关重要。研究证据可以影响全世界个人的生活,但知识差距的存在,部分原因是缺乏发表或展示的研究结果。Moher和同事报告说,超过50%的已完成的研究成果没有发表本文讨论了全球传播研究的必要性,并概述了研究人员可以采取的发表研究结果的步骤。
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引用次数: 0
Amyotrophic lateral sclerosis 肌萎缩侧索硬化症
Q4 Nursing Pub Date : 2020-01-01 DOI: 10.1097/01.CCN.0000612832.74020.6e
Vincent M. Vacca
www.nursingcriticalcare.com Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease, was first described in the 19th century by French neurologist Dr. Jean-Martin Charcot. In the 20th century, ALS also became known as Lou Gehrig disease, named after the famous New York Yankees baseball player who had the disease. Lou Gehrig died from ALS in 1941 at the age of 37.1 ALS is the most common form of motor neuron disease and is the third-most common neurodegenerative disorder behind Alzheimer and Parkinson diseases.2 There are an estimated 300,000 individuals currently living with ALS in the US.3 The median age of onset is 55 and the disease incidence peaks between 70 and 75 years of age.1,4 Males are affected more than females. About 90% of ALS cases are determined to be sporadic, or acquired, while the remainder are considered familial or hereditary. Known risk factors include age and family history, but there is now evidence that cigarette smoking is also a risk factor for ALS.1 This article provides critical care nurses with information about the etiology and pathophysiology, signs and symptoms, and diagnosis of ALS, as well as nursing considerations to help patients at end of life. Although treatment can slow disease progression, it is important for critical care nurses to understand that treatment is not curative. Abstract: About 7,000 new cases of amyotrophic lateral sclerosis (ALS) are diagnosed in the US every year. This neurodegenerative disease is rapidly progressive and always fatal. Although treatment can help slow disease progression, it is not curative. This article includes the etiology and pathophysiology of, signs and symptoms of, diagnosis of, and treatment for ALS, and special critical care nursing considerations to help patients at end of life.
www.ursingcriticalcare.com肌萎缩侧索硬化症(ALS),也称为运动神经元疾病,最早由法国神经学家Jean-Martin Charcot博士于19世纪描述。在20世纪,ALS也被称为Lou Gehrig病,以患有这种疾病的著名纽约洋基棒球运动员命名。Lou Gehrig于1941年死于ALS,享年37.1岁。ALS是最常见的运动神经元疾病,是仅次于阿尔茨海默病和帕金森病的第三常见神经退行性疾病。2据估计,美国目前有300000人患有ALS。3中位发病年龄为55岁,发病率在70至75岁之间达到峰值比女性多。大约90%的ALS病例被确定为散发性或获得性,而其余病例被认为是家族性或遗传性的。已知的风险因素包括年龄和家族史,但现在有证据表明吸烟也是ALS的一个风险因素。1本文为重症监护护士提供了有关ALS的病因和病理生理学、体征和症状、诊断的信息,以及帮助临终患者的护理注意事项。尽管治疗可以减缓疾病进展,但重要的是,重症监护护士要明白治疗是无效的。摘要:美国每年约有7000例新的肌萎缩侧索硬化症(ALS)确诊病例。这种神经退行性疾病进展迅速,而且总是致命的。尽管治疗可以帮助减缓疾病的进展,但它并不能治愈。本文包括ALS的病因和病理生理学、体征和症状、诊断和治疗,以及帮助临终患者的特殊重症护理注意事项。
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引用次数: 0
Determining the level of evidence: Nonresearch evidence. 确定证据水平:非研究证据。
Q4 Nursing Pub Date : 2020-01-01 DOI: 10.1097/01.CCN.0000612856.94212.9b
Amy Glasofer, Ann B. Townsend
ABSTRACTTo support evidence-based nursing practice, the authors provide guidelines for nonresearch evidence, which includes clinical practice guidelines, consensus or position statements, literature review, expert opinion, organizational experience, case reports, community standards, clinician experience, and consumer preferences. This is the third in a three-part series.
摘要为了支持循证护理实践,作者提供了非研究证据指南,包括临床实践指南、共识或立场声明、文献综述、专家意见、组织经验、病例报告、社区标准、临床医生经验和消费者偏好。这是三篇系列文章中的第三篇。
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引用次数: 2
Achieving zero harm 实现零伤害
Q4 Nursing Pub Date : 2020-01-01 DOI: 10.1097/01.ccn.0000612844.19763.16
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引用次数: 0
Hypertrophic cardiomyopathy 肥厚性心肌病
Q4 Nursing Pub Date : 2020-01-01 DOI: 10.1097/01.CCN.0000612840.12139.f1
Gail Larkin, Tamara L. Bellomo, Lenel Caze
www.nursingcriticalcare.com Mrs. M, 54, was admitted to the ED after a syncopal episode that resulted in a head injury. Based on an ECG and echocardiography findings, she was diagnosed with hypertrophic cardiomyopathy (HCM). After her head injury was determined non-life-threatening, the treating physician discharged her with instructions to follow up with a cardiologist and consider having family members tested for this genetic disorder. HCM is a common genetically determined heart muscle disease. Worldwide, without discrimination for race, gender, or ethnicity, HCM has a prevalence of approximately 1 out of 200 to 1 out of 300 in the general population. Based on current data, the Hypertrophic Cardiomyopathy Association estimates that HCM affects 1 million or more people in the US and 36 million or more worldwide.1 HCM is differentiated from other types of cardiomyopathy by the absence of any known clinical cause. In some instances, its Abstract: Hypertrophic cardiomyopathy (HCM), a common congenital heart disease, is the leading cause of sudden cardiac death in adolescents, young adults, and athletes. Older adults with HCM are less likely to experience sudden cardiac death, but their quality of life can be impaired. This article discusses diagnostic criteria, treatments, and critical care nursing interventions, including patient teaching, for adults with HCM.
www.ursingcriticalcare.com 54岁的M女士在一次导致头部受伤的syncopal发作后住进了急诊室。根据心电图和超声心动图检查结果,她被诊断为肥厚型心肌病(HCM)。在她的头部受伤被确定为没有生命危险后,治疗医生让她出院,并指示她与心脏病专家进行随访,并考虑让家人接受这种遗传疾病的检测。HCM是一种常见的遗传性心肌疾病。在世界范围内,在没有种族、性别或民族歧视的情况下,HCM在普通人群中的患病率约为200分之一至300分之一。根据目前的数据,肥厚型心肌病协会估计,HCM在美国影响100万或更多人,在全球影响3600万或更多。1 HCM与其他类型的心肌病的区别在于没有任何已知的临床原因。在某些情况下,其摘要:肥厚性心肌病(HCM)是一种常见的先天性心脏病,是青少年、年轻人和运动员心脏性猝死的主要原因。患有HCM的老年人不太可能发生心脏性猝死,但他们的生活质量可能会受损。本文讨论了成人HCM的诊断标准、治疗和重症护理干预措施,包括患者教学。
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引用次数: 0
Thank you for your resilience 谢谢你的坚韧
Q4 Nursing Pub Date : 2020-01-01 DOI: 10.1097/01.ccn.0000668576.18811.32
A. Palatnik
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引用次数: 0
Confidently caring for critically ill overweight and obese adults 自信地照顾重病、超重和肥胖的成年人
Q4 Nursing Pub Date : 2020-01-01 DOI: 10.1097/01.CCN.0000612872.24708.cb
Wanda Pritts
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引用次数: 1
期刊
Nursing Critical Care
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