首页 > 最新文献

Nutrition & Food Science最新文献

英文 中文
Postprandial glycemic response in different bakery formulations with adequate palatability: sex-related effects 具有足够适口性的不同烘焙配方的餐后血糖反应:与性别相关的影响
IF 1.2 Q2 Agricultural and Biological Sciences Pub Date : 2021-09-01 DOI: 10.1108/NFS-06-2021-0172
C. Niclis, Diego Prado, M. P. Díaz, E. A. Soria, C. Albrecht
{"title":"Postprandial glycemic response in different bakery formulations with adequate palatability: sex-related effects","authors":"C. Niclis, Diego Prado, M. P. Díaz, E. A. Soria, C. Albrecht","doi":"10.1108/NFS-06-2021-0172","DOIUrl":"https://doi.org/10.1108/NFS-06-2021-0172","url":null,"abstract":"","PeriodicalId":19376,"journal":{"name":"Nutrition & Food Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43321234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The prophylactic potential of Zingiber officinale flowers and leaves extract to mitigate hyperglycemia in Sprague Dawley rats 生姜花叶提取物对大鼠高血糖的预防作用
IF 1.2 Q2 Agricultural and Biological Sciences Pub Date : 2021-08-30 DOI: 10.1108/nfs-02-2021-0069
Saira Tanweer, T. Mehmood, S. Zainab, Z. Ahmad, M. Khan, A. Shehzad, A. Khaliq, F. Chughtai, Atif Liaqat
PurposeInnovative health-promoting approaches of the era have verified phytoceutics as one of the prime therapeutic tools to alleviate numerous health-related ailments. The purpose of this paper is to probe the nutraceutic potential of ginger flowers and leaves against hyperglycemia.Design/methodology/approachThe aqueous extracts of ginger flowers and leaves were observed on Sprague Dawley rats for 8 weeks. Two parallel studies were carried out based on dietary regimes: control and hyperglycemic diets. At the end of the experimental modus, the overnight fed rats were killed to determine the concentration of glucose and insulin in serum. The insulin resistance and insulin secretions were also calculated by formulae by considering fasting glucose and fasting insulin concentrations. Furthermore, the feed and drink intakes, body weight gain and hematological analysis were also carried out.FindingsIn streptozotocin-induced hyperglycemic rats, the ginger flowers extract depicted 5.62% reduction; however, ginger leaves extract reduced the glucose concentration up to 7.11% (p = 0.001). Similarly, ginger flowers extract uplifted the insulin concentration up to 3.07%, while, by ginger leaves extract, the insulin value increased to 4.11% (p = 0.002). For the insulin resistance, the ginger flower showed 5.32% decrease; however, the insulin resistance was reduced to 6.48% by ginger leaves (p = 0.014). Moreover, the insulin secretion increased to 18.9% by flower extract and 21.8% by ginger leave extract (p = 0.001). The feed intake and body weight gain increased momentously by the addition of ginger flowers and leaves; however, the drink intake and hematological analysis remained non-significant by the addition of ginger parts.Originality/valueConclusively, it was revealed that leaves have more hypoglycemic potential as compared to flowers.
目的:这个时代创新的健康促进方法已经证实植物制剂是缓解许多健康相关疾病的主要治疗工具之一。本文旨在探讨生姜花叶抗高血糖的营养潜力。设计/方法/方法:对Sprague Dawley大鼠进行为期8周的生姜花和姜叶水提物的观察。两项基于饮食制度的平行研究:控制饮食和高血糖饮食。实验模式结束时,处死过夜喂养大鼠,测定血清中葡萄糖和胰岛素的浓度。结合空腹血糖和空腹胰岛素浓度,用公式计算胰岛素抵抗和胰岛素分泌。此外,还进行了饲料和饮料采食量、体增重和血液学分析。结果表明:在链脲佐菌素诱导的高血糖大鼠中,姜花提取物降低血糖5.62%;姜叶提取物可使葡萄糖浓度降低7.11% (p = 0.001)。同样,姜花提取物可使胰岛素浓度升高3.07%,姜叶提取物可使胰岛素浓度升高4.11% (p = 0.002)。对于胰岛素抵抗,姜花降低了5.32%;而姜叶对胰岛素抵抗的抑制作用为6.48% (p = 0.014)。花提取物和姜叶提取物的胰岛素分泌分别提高了18.9%和21.8% (p = 0.001)。添加生姜花和生姜叶可显著提高采食量和增重;然而,加入生姜部分后,饮料摄入量和血液学分析仍然不显著。最后,研究表明,与花相比,叶子具有更强的降糖潜能。
{"title":"The prophylactic potential of Zingiber officinale flowers and leaves extract to mitigate hyperglycemia in Sprague Dawley rats","authors":"Saira Tanweer, T. Mehmood, S. Zainab, Z. Ahmad, M. Khan, A. Shehzad, A. Khaliq, F. Chughtai, Atif Liaqat","doi":"10.1108/nfs-02-2021-0069","DOIUrl":"https://doi.org/10.1108/nfs-02-2021-0069","url":null,"abstract":"\u0000Purpose\u0000Innovative health-promoting approaches of the era have verified phytoceutics as one of the prime therapeutic tools to alleviate numerous health-related ailments. The purpose of this paper is to probe the nutraceutic potential of ginger flowers and leaves against hyperglycemia.\u0000\u0000\u0000Design/methodology/approach\u0000The aqueous extracts of ginger flowers and leaves were observed on Sprague Dawley rats for 8 weeks. Two parallel studies were carried out based on dietary regimes: control and hyperglycemic diets. At the end of the experimental modus, the overnight fed rats were killed to determine the concentration of glucose and insulin in serum. The insulin resistance and insulin secretions were also calculated by formulae by considering fasting glucose and fasting insulin concentrations. Furthermore, the feed and drink intakes, body weight gain and hematological analysis were also carried out.\u0000\u0000\u0000Findings\u0000In streptozotocin-induced hyperglycemic rats, the ginger flowers extract depicted 5.62% reduction; however, ginger leaves extract reduced the glucose concentration up to 7.11% (p = 0.001). Similarly, ginger flowers extract uplifted the insulin concentration up to 3.07%, while, by ginger leaves extract, the insulin value increased to 4.11% (p = 0.002). For the insulin resistance, the ginger flower showed 5.32% decrease; however, the insulin resistance was reduced to 6.48% by ginger leaves (p = 0.014). Moreover, the insulin secretion increased to 18.9% by flower extract and 21.8% by ginger leave extract (p = 0.001). The feed intake and body weight gain increased momentously by the addition of ginger flowers and leaves; however, the drink intake and hematological analysis remained non-significant by the addition of ginger parts.\u0000\u0000\u0000Originality/value\u0000Conclusively, it was revealed that leaves have more hypoglycemic potential as compared to flowers.\u0000","PeriodicalId":19376,"journal":{"name":"Nutrition & Food Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42172250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The food choice determinants and adherence to Mediterranean diet in Iranian adults before and during COVID-19 lockdown: population-based study 在COVID-19封锁之前和期间,伊朗成年人的食物选择决定因素和对地中海饮食的坚持:基于人群的研究
IF 1.2 Q2 Agricultural and Biological Sciences Pub Date : 2021-08-25 DOI: 10.1108/NFS-01-2021-0044
M. Mohajeri, F. Ghannadiasl, Sajad Narimani, A. Nemati
Purpose: During the Coronavirus Disease 2019 (COVID-19) pandemic, some changes in dietary intake were observed. However, the determinants of food choice and adherence to the Mediterranean diet (MD) in this period were not studied so far for Iranian adults. This study aimed to assess the food choice determinants changes and Adherence to the MD of Iranian adults. Design/methodology/approach: This study was a cross-sectional study that was conducted from April 2019 to May 2020, based on the snowball sampling, and a total number of 2,540 adults from all the regions of Iran participated. The Food Choice Questionnaire was used to analyze food choice determinants, and the validated ten-item MD adherence screener was used to assess the adherence to the MD. Findings: Before the COVID-19 quarantine, sensory appeal and price were the most important factors in Iranian food choice (with the highest scores), but during the COVID-19 pandemic the important food choice determinants were health and weight control. Consumption of vegetables (71.85% vs 40.07%), fruits (60.70% vs 38.74%), legumes (24.72% vs 12.38%) and nuts (14.33%) increased significantly after the outbreak of quarantine. © 2021, Emerald Publishing Limited.
目的:在2019冠状病毒病(新冠肺炎)大流行期间,观察到饮食摄入量的一些变化。然而,到目前为止,还没有对伊朗成年人在这一时期选择食物和坚持地中海饮食(MD)的决定因素进行研究。本研究旨在评估伊朗成年人的食物选择决定因素变化和对MD的遵守情况。设计/方法/方法:这项研究是一项横断面研究,于2019年4月至2020年5月进行,基于滚雪球抽样,来自伊朗所有地区的2540名成年人参与了研究。食物选择问卷用于分析食物选择决定因素,经验证的十项MD依从性筛查器用于评估MD的依从性。研究结果:在新冠肺炎隔离之前,感官吸引力和价格是伊朗食物选择的最重要因素(得分最高),但在新冠肺炎大流行期间,重要的食物选择决定因素是健康和体重控制。检疫爆发后,蔬菜(71.85%对40.07%)、水果(60.70%对38.74%)、豆类(24.72%对12.38%)和坚果(14.33%)的消费量显著增加。©2021,翡翠出版有限公司。
{"title":"The food choice determinants and adherence to Mediterranean diet in Iranian adults before and during COVID-19 lockdown: population-based study","authors":"M. Mohajeri, F. Ghannadiasl, Sajad Narimani, A. Nemati","doi":"10.1108/NFS-01-2021-0044","DOIUrl":"https://doi.org/10.1108/NFS-01-2021-0044","url":null,"abstract":"Purpose: During the Coronavirus Disease 2019 (COVID-19) pandemic, some changes in dietary intake were observed. However, the determinants of food choice and adherence to the Mediterranean diet (MD) in this period were not studied so far for Iranian adults. This study aimed to assess the food choice determinants changes and Adherence to the MD of Iranian adults. Design/methodology/approach: This study was a cross-sectional study that was conducted from April 2019 to May 2020, based on the snowball sampling, and a total number of 2,540 adults from all the regions of Iran participated. The Food Choice Questionnaire was used to analyze food choice determinants, and the validated ten-item MD adherence screener was used to assess the adherence to the MD. Findings: Before the COVID-19 quarantine, sensory appeal and price were the most important factors in Iranian food choice (with the highest scores), but during the COVID-19 pandemic the important food choice determinants were health and weight control. Consumption of vegetables (71.85% vs 40.07%), fruits (60.70% vs 38.74%), legumes (24.72% vs 12.38%) and nuts (14.33%) increased significantly after the outbreak of quarantine. © 2021, Emerald Publishing Limited.","PeriodicalId":19376,"journal":{"name":"Nutrition & Food Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2021-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42578290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Parents’ perceived knowledge about food-related behaviours influencing speech-language competences of preschool children 父母食物相关行为认知对学龄前儿童言语语言能力的影响
IF 1.2 Q2 Agricultural and Biological Sciences Pub Date : 2021-08-25 DOI: 10.1108/nfs-04-2021-0136
Goreti Botelho, E. Rodrigues, R. Matos, J. Lameiras
PurposeThere is a relationship between eating behaviours and the development of speech-language competences during childhood. This study aims to evaluate the impact of interdisciplinary sessions on food and speech-language education with children’s parents.Design/methodology/approachThe session was focused on healthy eating habits and behaviours that may improve or impair child speech competence. Using a self-administered questionnaire, before and immediately after the session, parents from 11 preschools, answered 12 questions, on a five-point Likert scale. Questionnaires from the final sample (n = 96) were statistically analysed using the Wilcoxon Signed-Rank Test.FindingsStatistical analysis revealed statistically significant differences in answers to six questions between pre and post intervention: items 1 (Z = −5.04; p < 0.001), 2 (Z = −3.68; p < 0.001), 3 (Z = −4.12; p < 0.001), 4 (Z = −5.87; p < 0.001), 9 (Z = −2.73; p = 0.006) and 12 (Z = −2.00; p = 0.046). The questionnaire responses after the session showed that parents became more aware of the relationship between the two areas addressed. In addition, the subjects presented more assertiveness in their answers after the educational intervention of the nutritionist and the speech therapist.Practical implicationsThe study showed the importance of associating topics on food and speech-language education and both being addressed simultaneously to parents. The empowerment of parents and other caregivers about feeding and speech-language development may increase their motivation to foster child healthy eating behaviours. It is also desirable to extend this kind of interdisciplinary intervention to other preschools.Originality/valueThis study fulfils an identified need to study the perceived knowledge of parents about the food-related behaviours influencing speech-language competences of children.
目的研究儿童时期饮食行为与语言能力发展之间的关系。本研究旨在评估跨学科课程对儿童父母食物和语言教育的影响。设计/方法/方法会议的重点是健康的饮食习惯和行为,可以提高或损害儿童的语言能力。在课程开始前和结束后,来自11所幼儿园的家长填写了一份自我填写的问卷,回答了12个问题,李克特量表为5分。最终样本(n = 96)的问卷采用Wilcoxon sign - rank检验进行统计分析。统计分析显示干预前和干预后6个问题的回答差异有统计学意义:第1项(Z =−5.04;p < 0.001), 2 (Z =−3.68;p < 0.001), 3 (Z = - 4.12;p < 0.001), 4 (Z = - 5.87;p < 0.001), 9 (Z = - 2.73;p = 0.006)和12 (Z = - 2.00;P = 0.046)。会议结束后的问卷调查显示,家长们更加意识到这两个领域之间的关系。此外,经过营养学家和语言治疗师的教育干预后,被试在回答中表现出更强的自信。实际意义该研究表明,将食物和语言教育的主题联系起来,并同时向父母提出这两个主题的重要性。父母和其他照顾者在喂养和语言发展方面的能力可能会增加他们培养儿童健康饮食行为的动机。将这种跨学科的干预扩展到其他学前班也是可取的。原创性/价值本研究满足了研究父母对食物相关行为影响儿童言语语言能力的感知知识的需求。
{"title":"Parents’ perceived knowledge about food-related behaviours influencing speech-language competences of preschool children","authors":"Goreti Botelho, E. Rodrigues, R. Matos, J. Lameiras","doi":"10.1108/nfs-04-2021-0136","DOIUrl":"https://doi.org/10.1108/nfs-04-2021-0136","url":null,"abstract":"\u0000Purpose\u0000There is a relationship between eating behaviours and the development of speech-language competences during childhood. This study aims to evaluate the impact of interdisciplinary sessions on food and speech-language education with children’s parents.\u0000\u0000\u0000Design/methodology/approach\u0000The session was focused on healthy eating habits and behaviours that may improve or impair child speech competence. Using a self-administered questionnaire, before and immediately after the session, parents from 11 preschools, answered 12 questions, on a five-point Likert scale. Questionnaires from the final sample (n = 96) were statistically analysed using the Wilcoxon Signed-Rank Test.\u0000\u0000\u0000Findings\u0000Statistical analysis revealed statistically significant differences in answers to six questions between pre and post intervention: items 1 (Z = −5.04; p < 0.001), 2 (Z = −3.68; p < 0.001), 3 (Z = −4.12; p < 0.001), 4 (Z = −5.87; p < 0.001), 9 (Z = −2.73; p = 0.006) and 12 (Z = −2.00; p = 0.046). The questionnaire responses after the session showed that parents became more aware of the relationship between the two areas addressed. In addition, the subjects presented more assertiveness in their answers after the educational intervention of the nutritionist and the speech therapist.\u0000\u0000\u0000Practical implications\u0000The study showed the importance of associating topics on food and speech-language education and both being addressed simultaneously to parents. The empowerment of parents and other caregivers about feeding and speech-language development may increase their motivation to foster child healthy eating behaviours. It is also desirable to extend this kind of interdisciplinary intervention to other preschools.\u0000\u0000\u0000Originality/value\u0000This study fulfils an identified need to study the perceived knowledge of parents about the food-related behaviours influencing speech-language competences of children.\u0000","PeriodicalId":19376,"journal":{"name":"Nutrition & Food Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2021-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46608408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between iron supplementation and anaemia in pregnant women in Ghana 加纳孕妇补铁与贫血之间的关系
IF 1.2 Q2 Agricultural and Biological Sciences Pub Date : 2021-08-23 DOI: 10.1108/nfs-03-2021-0105
L. Owusu, C. Apprey, Abigail Kusi-Amponsah Diji, A. Adebanji
PurposeThe purpose of the study was to assess the association between iron intake and anaemia during pregnancy as well as estimate the prevalence and magnitude of anaemia in pregnancy.Design/methodology/approachA retrospective case-control study was conducted on 383 postnatal women at four health-care facilities. Data on iron supplementation and haemoglobin (Hb) levels during pregnancy was collected from the respondents. Spearman, Pearson Chi-square tests of independence were used to measure associations between variables, whereas a log-linear model was adopted to ascertain the level of interaction among variables. All p-values < 0.05 were considered statistically significant.FindingsResults show 54.3% prevalence of anaemia at registration and 33.6% at 36 weeks of pregnancy, p < 0.001. Iron supplement intake during pregnancy was 96.3%. The log-linear analysis model retained the Parity × Marital Status interaction across the levels of anaemia (p < 0.001). Relative to married pregnant women, single pregnant women were 6.38% more likely to be anaemic (OR = 1.06).Research limitations/implicationsOne of the limitations of retrospective studies is recall bias; however, this was likely to be minimal, as participants were approached within 8 days after delivery. Despite this, this study still holds promise as it reports a rather high prevalence of anaemia at 36 weeks even with the high intake of iron.Originality/valueAnaemia in pregnancy is a major public health issue because of the consequential outcomes on maternal and child health. The study identified a high prevalence of anaemia at registration; which could be the basis for intensifying pre-natal iron supplementation before pregnancy.
目的本研究的目的是评估铁摄入量与妊娠期贫血之间的关系,并估计妊娠期贫血的患病率和程度。设计/方法/方法对四家保健机构的383名产后妇女进行了回顾性病例对照研究。从调查对象那里收集了怀孕期间铁补充剂和血红蛋白(Hb)水平的数据。采用Spearman、Pearson卡方独立性检验来衡量变量之间的相关性,而采用对数线性模型来确定变量之间的相互作用水平。p值< 0.05均认为有统计学意义。结果显示,登记时的贫血患病率为54.3%,妊娠36周时为33.6%,p < 0.001。怀孕期间铁补充剂的摄入量为96.3%。对数线性分析模型保留了胎次与婚姻状况在贫血水平之间的相互作用(p < 0.001)。与已婚孕妇相比,单身孕妇贫血的可能性高6.38% (OR = 1.06)。研究局限性/意义回顾性研究的局限性之一是回忆偏倚;然而,这可能是最小的,因为参与者是在分娩后8天内接触的。尽管如此,这项研究仍然有希望,因为它报告了36周时贫血的患病率相当高,即使摄入了大量的铁。独创性/价值妊娠期贫血是一个重大的公共卫生问题,因为它会对孕产妇和儿童健康造成后果。该研究确定了登记时贫血的高患病率;这可能是在怀孕前加强产前铁补充的基础。
{"title":"Association between iron supplementation and anaemia in pregnant women in Ghana","authors":"L. Owusu, C. Apprey, Abigail Kusi-Amponsah Diji, A. Adebanji","doi":"10.1108/nfs-03-2021-0105","DOIUrl":"https://doi.org/10.1108/nfs-03-2021-0105","url":null,"abstract":"\u0000Purpose\u0000The purpose of the study was to assess the association between iron intake and anaemia during pregnancy as well as estimate the prevalence and magnitude of anaemia in pregnancy.\u0000\u0000\u0000Design/methodology/approach\u0000A retrospective case-control study was conducted on 383 postnatal women at four health-care facilities. Data on iron supplementation and haemoglobin (Hb) levels during pregnancy was collected from the respondents. Spearman, Pearson Chi-square tests of independence were used to measure associations between variables, whereas a log-linear model was adopted to ascertain the level of interaction among variables. All p-values < 0.05 were considered statistically significant.\u0000\u0000\u0000Findings\u0000Results show 54.3% prevalence of anaemia at registration and 33.6% at 36 weeks of pregnancy, p < 0.001. Iron supplement intake during pregnancy was 96.3%. The log-linear analysis model retained the Parity × Marital Status interaction across the levels of anaemia (p < 0.001). Relative to married pregnant women, single pregnant women were 6.38% more likely to be anaemic (OR = 1.06).\u0000\u0000\u0000Research limitations/implications\u0000One of the limitations of retrospective studies is recall bias; however, this was likely to be minimal, as participants were approached within 8 days after delivery. Despite this, this study still holds promise as it reports a rather high prevalence of anaemia at 36 weeks even with the high intake of iron.\u0000\u0000\u0000Originality/value\u0000Anaemia in pregnancy is a major public health issue because of the consequential outcomes on maternal and child health. The study identified a high prevalence of anaemia at registration; which could be the basis for intensifying pre-natal iron supplementation before pregnancy.\u0000","PeriodicalId":19376,"journal":{"name":"Nutrition & Food Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2021-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43340083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Cafeteria diet decreases sucrose preference and increases the sensitivity of risperidone in the caloric intake of Wistar rats 自助餐厅的饮食减少了蔗糖的偏好,增加了威斯塔大鼠对利培酮的敏感性
IF 1.2 Q2 Agricultural and Biological Sciences Pub Date : 2021-08-18 DOI: 10.1108/nfs-05-2021-0148
J. S. Gonçalves, Arthur Rocha-Gomes, Amanda Escobar Teixeira, Alexandre Alves da Silva, M. R. Lessa, N. V. Dessimoni-Pinto, S. S. Seixas, T. R. Riul
PurposeThe purpose of this study was to evaluate the increase in sensitivity of a single risperidone administration in relation to energy intake of Wistar rats treated with cafeteria diet from birth to adulthood (119 days).Design/methodology/approachDuring the lactation period, six litters of Wistar rats (dam + 8 pups each litter) were fed one of the following two diets: Control (n = 3) or Cafeteria (n = 3) diets and water ad libitum. After weaning, the males were placed in individual cages, receiving the same diet offered to their respective dams (Control = 18; or Cafeteria = 18) until adulthood (119 postnatal days). The following parameters were evaluated: food and energy intake; macronutrient intake; weight gain; adipose tissue relative weight; sucrose preference; food intake after an administration of risperidone (0.1 mg/kg body weight).FindingsThe Cafeteria group showed a higher energy intake in relation to the Control group (p < 0.001). The consumption of energy beyond the individual needs can be understood as a hyperphagic condition. Also, the Cafeteria group reported greater weight gain (p = 0.048) and accumulation of adipose tissue (p < 0.001) with respect to the Control group. These results indicate that the cafeteria diet generated obesity in animals. The Cafeteria group showed reduced sucrose preference (p = 0.031), which is associated with the development of anhedonia-like behavior. In the food intake test, risperidone showed a greater sensitivity in Cafeteria animals, promoting a decrease in their energy intake in relation to the Control group that received risperidone (p = 0.040).Originality/valueThe cafeteria diet promoted hyperphagia, anhedonia-like behavior and obesity in animals. Acute risperidone administration showed greater sensitivity in the Cafeteria group, with a decrease in energy intake. The reported effects may be related to a downregulation of the dopaminergic system in the NAc region.
目的本研究的目的是评估从出生到成年(119天)接受自助饮食的Wistar大鼠,单次给药利培酮的敏感性增加与能量摄入的关系。设计/方法/方法在哺乳期,6窝Wistar大鼠(每窝坝+ 8只幼鼠)分别饲喂对照饲粮(n = 3)和自助饲粮(n = 3),外加水。断奶后,雄性被放置在单独的笼子里,接受与各自水坝相同的饮食(对照组= 18;或自助餐厅= 18),直到成年(出生后119天)。评估以下参数:食物和能量摄入量;大量营养素的摄入量;体重增加;脂肪组织相对重量;蔗糖的偏好;给予利培酮(0.1 mg/kg体重)后的食物摄入量。研究结果:与对照组相比,自助餐厅组的能量摄入更高(p < 0.001)。超出个人需要的能量消耗可以理解为一种贪食状态。此外,与对照组相比,自助餐厅组的体重增加(p = 0.048)和脂肪组织积累(p < 0.001)更大。这些结果表明,自助餐厅的饮食会导致动物肥胖。自助餐厅组表现出较低的蔗糖偏好(p = 0.031),这与快感缺乏样行为的发展有关。在食物摄入测试中,利培酮在自助餐厅的动物中表现出更大的敏感性,与接受利培酮的对照组相比,利培酮促进了它们能量摄入的减少(p = 0.040)。原创/价值自助餐厅的饮食促进了动物的贪食、快感缺乏样行为和肥胖。急性利培酮给药在自助餐厅组显示出更高的敏感性,能量摄入减少。报道的效果可能与NAc区域多巴胺能系统的下调有关。
{"title":"Cafeteria diet decreases sucrose preference and increases the sensitivity of risperidone in the caloric intake of Wistar rats","authors":"J. S. Gonçalves, Arthur Rocha-Gomes, Amanda Escobar Teixeira, Alexandre Alves da Silva, M. R. Lessa, N. V. Dessimoni-Pinto, S. S. Seixas, T. R. Riul","doi":"10.1108/nfs-05-2021-0148","DOIUrl":"https://doi.org/10.1108/nfs-05-2021-0148","url":null,"abstract":"\u0000Purpose\u0000The purpose of this study was to evaluate the increase in sensitivity of a single risperidone administration in relation to energy intake of Wistar rats treated with cafeteria diet from birth to adulthood (119 days).\u0000\u0000\u0000Design/methodology/approach\u0000During the lactation period, six litters of Wistar rats (dam + 8 pups each litter) were fed one of the following two diets: Control (n = 3) or Cafeteria (n = 3) diets and water ad libitum. After weaning, the males were placed in individual cages, receiving the same diet offered to their respective dams (Control = 18; or Cafeteria = 18) until adulthood (119 postnatal days). The following parameters were evaluated: food and energy intake; macronutrient intake; weight gain; adipose tissue relative weight; sucrose preference; food intake after an administration of risperidone (0.1 mg/kg body weight).\u0000\u0000\u0000Findings\u0000The Cafeteria group showed a higher energy intake in relation to the Control group (p < 0.001). The consumption of energy beyond the individual needs can be understood as a hyperphagic condition. Also, the Cafeteria group reported greater weight gain (p = 0.048) and accumulation of adipose tissue (p < 0.001) with respect to the Control group. These results indicate that the cafeteria diet generated obesity in animals. The Cafeteria group showed reduced sucrose preference (p = 0.031), which is associated with the development of anhedonia-like behavior. In the food intake test, risperidone showed a greater sensitivity in Cafeteria animals, promoting a decrease in their energy intake in relation to the Control group that received risperidone (p = 0.040).\u0000\u0000\u0000Originality/value\u0000The cafeteria diet promoted hyperphagia, anhedonia-like behavior and obesity in animals. Acute risperidone administration showed greater sensitivity in the Cafeteria group, with a decrease in energy intake. The reported effects may be related to a downregulation of the dopaminergic system in the NAc region.\u0000","PeriodicalId":19376,"journal":{"name":"Nutrition & Food Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2021-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42925644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Screen time-based sedentary behaviour, eating regulation and weight status of university students during the COVID-19 lockdown 新冠肺炎封锁期间大学生基于时间的久坐行为、饮食调节和体重状况筛查
IF 1.2 Q2 Agricultural and Biological Sciences Pub Date : 2021-08-18 DOI: 10.1108/nfs-05-2021-0156
S. Tan, S. Tan, Chin Xuan Tan
PurposeThis study aims to investigate the relationships among screen time-based sedentary behaviour, eating self-regulatory skills and weight status among private university students during the Movement Control Order (MCO).Design/methodology/approachA total of 186 private university students was enrolled in this cross-sectional study using a combination of snowball and purposive sampling approaches. Anthropometric measurements, including body height, body weight before and during the MCO enforcement were self-reported by the respondents. Screen-time based sedentary behaviour sedentary behaviour was evaluated using HELENA sedentary behaviour questionnaire, whereas the Self-Regulation of Eating Behaviour Questionnaire (SREBQ) was used to determine the eating self-regulatory skills in MCO.FindingsRespondents spent most of the time on the internet for non-study purposes (148 ± 77.7 min). It is also noted that 64.5% of the respondents had medium eating self-regulatory skill during the MCO, with an average score of 3.0 ± 0.5. Findings from path analysis confirmed that poor eating self-regulation significantly contributed to the weight gain during home confinement (ß = −0.24, p = 0.01). In conclusion, eating self-regulation, but not total screen time, emerged as the determinant for weight gain during the COVID-19 lockdown.Originality/valueAccording to the authors’ knowledge, this study was among the few that investigated sedentary behaviour, eating self-regulatory skills and weight status of university students during the COVID-19 pandemic.
目的本研究旨在探讨基于屏幕时间的久坐行为,运动控制令(MCO)期间私立大学学生的饮食自我调节技能和体重状况。设计/方法/方法共有186名私立大学学生参加了这项横断面研究,采用滚雪球和有目的的抽样方法相结合。被调查者自我报告了MCO实施前和实施期间的人体测量结果,包括身高、体重。基于屏幕时间的久坐行为久坐行为使用HELENA久坐行为问卷进行评估,而饮食行为自我调节问卷(SREBQ)用于确定MCO的饮食自我调节技能。发现受访者大部分时间都在互联网上用于非研究目的(148 ± 77.7 分钟)。还应注意的是,64.5%的受访者在MCO期间具有中等的饮食自我调节能力,平均得分为3.0 ± 0.5.路径分析结果证实,不良的饮食自我调节显著促进了家庭分娩期间的体重增加(ß=−0.24,p=0.01)。总之,在新冠肺炎封锁期间,饮食自我调节(而不是总筛查时间)成为体重增加的决定因素。原创/价值据作者所知,这项研究是少数调查新冠肺炎大流行期间大学生久坐行为、饮食自我调节技能和体重状况的研究之一。
{"title":"Screen time-based sedentary behaviour, eating regulation and weight status of university students during the COVID-19 lockdown","authors":"S. Tan, S. Tan, Chin Xuan Tan","doi":"10.1108/nfs-05-2021-0156","DOIUrl":"https://doi.org/10.1108/nfs-05-2021-0156","url":null,"abstract":"\u0000Purpose\u0000This study aims to investigate the relationships among screen time-based sedentary behaviour, eating self-regulatory skills and weight status among private university students during the Movement Control Order (MCO).\u0000\u0000\u0000Design/methodology/approach\u0000A total of 186 private university students was enrolled in this cross-sectional study using a combination of snowball and purposive sampling approaches. Anthropometric measurements, including body height, body weight before and during the MCO enforcement were self-reported by the respondents. Screen-time based sedentary behaviour sedentary behaviour was evaluated using HELENA sedentary behaviour questionnaire, whereas the Self-Regulation of Eating Behaviour Questionnaire (SREBQ) was used to determine the eating self-regulatory skills in MCO.\u0000\u0000\u0000Findings\u0000Respondents spent most of the time on the internet for non-study purposes (148 ± 77.7 min). It is also noted that 64.5% of the respondents had medium eating self-regulatory skill during the MCO, with an average score of 3.0 ± 0.5. Findings from path analysis confirmed that poor eating self-regulation significantly contributed to the weight gain during home confinement (ß = −0.24, p = 0.01). In conclusion, eating self-regulation, but not total screen time, emerged as the determinant for weight gain during the COVID-19 lockdown.\u0000\u0000\u0000Originality/value\u0000According to the authors’ knowledge, this study was among the few that investigated sedentary behaviour, eating self-regulatory skills and weight status of university students during the COVID-19 pandemic.\u0000","PeriodicalId":19376,"journal":{"name":"Nutrition & Food Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2021-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44072314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Effects of camel milk hydrolysate on blood pressure and biochemical parameters in fructose-induced hypertensive rats 骆驼乳水解液对果糖诱导的高血压大鼠血压及生化指标的影响
IF 1.2 Q2 Agricultural and Biological Sciences Pub Date : 2021-08-13 DOI: 10.1108/nfs-04-2021-0130
Mohammad A. Alshuniaber, O. Alhaj, Qasem M A Abdallah, H. Jahrami
PurposeThis study aims to investigate the antihypertensive effect of camel milk hydrolysate in rats with fructose-induced hypertension.Design/methodology/approachThe antihypertensive effect of fermented camel milk was determined using 6 groups comprising 36 Wistar male rats. Blood pressure of rats was altered via exposure to a 10% fructose (w/v) diet in drinking water for 3 weeks before conducting 21 days of treatment. The authors conducted the experiment for short and long term using different doses of 800 and 1,200 mg/kg body weight. Serum was used to assay total cholesterol (TC), triglyceride (TG), glucose and insulin levels using standard biochemical kits.FindingsThe group that received 1,200 mg hydrolysate camel milk (HM) has significantly (p = 0.003) reduced systolic and diastolic blood pressure after a short exposure time (4–8 h). These effects were significantly (p = 0.005) comparable to the nifedipine (NIF) drug group. Similar long-term (21 days) effects on blood pressure were observed in 1,200 mg HM and NIF groups. Angiotensin-converting enzyme (ACE) activity and levels were also reduced in a correlation with blood pressure reduction only in HM1200 and HM800 treated groups. The authors observed no significant effect on blood pressure in groups receiving the 800 mg HM or 1,200 mg unhydrolyzed camel milk (UM). Rats receiving the 10% fructose diet showed significant differences from control rats regarding their blood biochemistry, including TG, TC, blood glucose and insulin levels. Rats in groups NIF, HM1200 and HM800 showed a significant (p < 0.05) reduction in serum glucose, insulin, TG and TC levels toward the baseline level.Research limitations/implicationsFurther mechanistic investigation on the HM antihypertensive activity is highly recommended before suggesting HM as a product to reduce blood pressure. While drug–food interaction between HM and antihypertensive drugs, especially ACE inhibitors, is probable, UM seems not to affect blood pressure or ACE activity and therefore is expected to have no or minimal effects on the activity of other antihypertensive drugs. Investigation of ACE expression from various organs including lungs and leukocytes is highly recommended in future works using sodium dodecyl-sulfate polyacrylamide gel electrophoresis and western blot analysis or reverse transcription polymerase chain reaction.Originality/valueNo previous studies have measured the antihypertensive activity of milk hydrolysate mediated by the reduction of ACE activity and levels in plasma. Mechanisms involved in attenuating the levels of ACE warrant further investigation.
目的研究骆驼乳水解物对果糖性高血压大鼠的降压作用。设计/方法/方法使用6组(包括36只Wistar雄性大鼠)测定发酵骆驼乳的降压作用。大鼠的血压通过暴露于饮用水中的10%果糖(w/v)饮食改变3 进行21之前的周 治疗天数。作者使用800和1200的不同剂量进行了短期和长期的实验 mg/kg体重。血清用于使用标准生化试剂盒测定总胆固醇(TC)、甘油三酯(TG)、葡萄糖和胰岛素水平。Findings收到1200 mg水解骆驼奶(HM)在短时间暴露后显著(p=0.003)降低了收缩压和舒张压(4-8 h) 。这些效果与硝苯地平(NIF)药物组显著相当(p=0.005)。类似的长期(21 天)对血压的影响 mg HM和NIF组。仅在HM1200和HM800治疗组中,血管紧张素转换酶(ACE)活性和水平也与血压下降相关。作者观察到,在接受800 mg HM或1200 mg未水解骆驼奶(UM)。接受10%果糖饮食的大鼠在血液生化方面与对照大鼠表现出显著差异,包括TG、TC、血糖和胰岛素水平。NIF、HM1200和HM800组大鼠的血糖、胰岛素、TG和TC水平向基线水平显著降低(p<0.05)。研究局限性/含义在建议HM作为降压产品之前,强烈建议对HM降压活性进行进一步的机制研究。虽然HM和抗高血压药物,特别是ACE抑制剂之间可能存在药物-食物相互作用,但UM似乎不会影响血压或ACE活性,因此预计对其他抗高血压药物的活性没有影响或影响很小。在未来的工作中,强烈建议使用十二烷基硫酸钠-聚丙烯酰胺凝胶电泳和蛋白质印迹分析或逆转录聚合酶链式反应来研究包括肺和白细胞在内的各种器官的ACE表达。独创性/价值以前没有研究通过降低ACE活性和血浆水平来测量牛奶水解物的抗高血压活性。降低ACE水平的机制值得进一步研究。
{"title":"Effects of camel milk hydrolysate on blood pressure and biochemical parameters in fructose-induced hypertensive rats","authors":"Mohammad A. Alshuniaber, O. Alhaj, Qasem M A Abdallah, H. Jahrami","doi":"10.1108/nfs-04-2021-0130","DOIUrl":"https://doi.org/10.1108/nfs-04-2021-0130","url":null,"abstract":"\u0000Purpose\u0000This study aims to investigate the antihypertensive effect of camel milk hydrolysate in rats with fructose-induced hypertension.\u0000\u0000\u0000Design/methodology/approach\u0000The antihypertensive effect of fermented camel milk was determined using 6 groups comprising 36 Wistar male rats. Blood pressure of rats was altered via exposure to a 10% fructose (w/v) diet in drinking water for 3 weeks before conducting 21 days of treatment. The authors conducted the experiment for short and long term using different doses of 800 and 1,200 mg/kg body weight. Serum was used to assay total cholesterol (TC), triglyceride (TG), glucose and insulin levels using standard biochemical kits.\u0000\u0000\u0000Findings\u0000The group that received 1,200 mg hydrolysate camel milk (HM) has significantly (p = 0.003) reduced systolic and diastolic blood pressure after a short exposure time (4–8 h). These effects were significantly (p = 0.005) comparable to the nifedipine (NIF) drug group. Similar long-term (21 days) effects on blood pressure were observed in 1,200 mg HM and NIF groups. Angiotensin-converting enzyme (ACE) activity and levels were also reduced in a correlation with blood pressure reduction only in HM1200 and HM800 treated groups. The authors observed no significant effect on blood pressure in groups receiving the 800 mg HM or 1,200 mg unhydrolyzed camel milk (UM). Rats receiving the 10% fructose diet showed significant differences from control rats regarding their blood biochemistry, including TG, TC, blood glucose and insulin levels. Rats in groups NIF, HM1200 and HM800 showed a significant (p < 0.05) reduction in serum glucose, insulin, TG and TC levels toward the baseline level.\u0000\u0000\u0000Research limitations/implications\u0000Further mechanistic investigation on the HM antihypertensive activity is highly recommended before suggesting HM as a product to reduce blood pressure. While drug–food interaction between HM and antihypertensive drugs, especially ACE inhibitors, is probable, UM seems not to affect blood pressure or ACE activity and therefore is expected to have no or minimal effects on the activity of other antihypertensive drugs. Investigation of ACE expression from various organs including lungs and leukocytes is highly recommended in future works using sodium dodecyl-sulfate polyacrylamide gel electrophoresis and western blot analysis or reverse transcription polymerase chain reaction.\u0000\u0000\u0000Originality/value\u0000No previous studies have measured the antihypertensive activity of milk hydrolysate mediated by the reduction of ACE activity and levels in plasma. Mechanisms involved in attenuating the levels of ACE warrant further investigation.\u0000","PeriodicalId":19376,"journal":{"name":"Nutrition & Food Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2021-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44860701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Cross-sectional associations of dietary patterns with health status and smoking-related knowledge, attitudes and practices (KAP) among Bangladeshi adolescent smokers 孟加拉国青少年吸烟者饮食模式与健康状况和吸烟相关知识、态度和做法的横断面关联
IF 1.2 Q2 Agricultural and Biological Sciences Pub Date : 2021-08-09 DOI: 10.1108/nfs-04-2021-0118
Suvasish Das Shuvo, Md. Eunus Ali, Md. Masudur Rahman, A. Taher, M. Asaduzzaman, Md Toufiq Elahi, Md Ashrafuzzaman Zahid, D. Paul, Deepa Roy
PurposeThis study aims to evaluate the association between dietary patterns with health status and smoking-related knowledge, attitudes and practices (s-KAP) among Bangladeshi adolescent smokers.Design/methodology/approachAn analytical cross-sectional study was conducted among 205 randomly selected adolescents. Socio-demographic, health status, s-KAP related data were collected in face-to-face interviews. Dietary intake data were calculated using the food frequency questionnaire.FindingsThe practices score (44.8%) was comparatively poor among adolescent smokers. Among the respondents, around 56.1%, 38.1% and 49.3% were suffering from gastric problems, nausea and the loss of appetite, respectively, because of smoking. There was a significant relationship between dietary diversity and the occurrence of several diseases such as gastric problems, nausea and loss of appetite. The respondents who consumed fresh fruits and vegetables regularly might reduce gastric problems (OR: 0.53, 95% CI: 0.27–1.04 and OR: 0.64, 95% CI: 0.25–1.65), nausea (OR: 0.72, 95% CI: 0.38–1.37 and OR: 0.28, 95% CI: 0.13–0.84) and loss of appetite (OR: 0.52, 95% CI: 0.32–1.21 and OR: 0.16 95% CI: 0.27–0.68).Originality/valueIn conclusion, smoking has been associated with multiple health problems because of poor practices score. Consumption of a balanced diet, better smoking-related knowledge, attitudes and practices needs to be improved among adolescents.
目的本研究旨在评估孟加拉国青少年吸烟者的饮食模式与健康状况和吸烟相关知识、态度和行为(s-KAP)之间的关系。设计/方法/方法对随机选取的205名青少年进行了一项分析性横断面研究。通过面对面访谈收集社会人口统计学、健康状况、s-KAP相关数据。膳食摄入数据采用食物频率问卷计算。结果:青少年吸烟者的实践得分(44.8%)相对较低。在受访者中,因吸烟而出现胃病、恶心和食欲不振的比例分别为56.1%、38.1%和49.3%。饮食多样性与胃问题、恶心和食欲不振等几种疾病的发生有显著关系。经常食用新鲜水果和蔬菜的受访者可能会减少胃病(OR: 0.53, 95% CI: 0.27-1.04和OR: 0.64, 95% CI: 0.25-1.65),恶心(OR: 0.72, 95% CI: 0.38-1.37和OR: 0.28, 95% CI: 0.13-0.84)和食欲减退(OR: 0.52, 95% CI: 0.32-1.21和OR: 0.16, 95% CI: 0.27-0.68)。结论,吸烟与多种健康问题有关,因为不良习惯得分。需要改善青少年的均衡饮食、更好的吸烟相关知识、态度和做法。
{"title":"Cross-sectional associations of dietary patterns with health status and smoking-related knowledge, attitudes and practices (KAP) among Bangladeshi adolescent smokers","authors":"Suvasish Das Shuvo, Md. Eunus Ali, Md. Masudur Rahman, A. Taher, M. Asaduzzaman, Md Toufiq Elahi, Md Ashrafuzzaman Zahid, D. Paul, Deepa Roy","doi":"10.1108/nfs-04-2021-0118","DOIUrl":"https://doi.org/10.1108/nfs-04-2021-0118","url":null,"abstract":"\u0000Purpose\u0000This study aims to evaluate the association between dietary patterns with health status and smoking-related knowledge, attitudes and practices (s-KAP) among Bangladeshi adolescent smokers.\u0000\u0000\u0000Design/methodology/approach\u0000An analytical cross-sectional study was conducted among 205 randomly selected adolescents. Socio-demographic, health status, s-KAP related data were collected in face-to-face interviews. Dietary intake data were calculated using the food frequency questionnaire.\u0000\u0000\u0000Findings\u0000The practices score (44.8%) was comparatively poor among adolescent smokers. Among the respondents, around 56.1%, 38.1% and 49.3% were suffering from gastric problems, nausea and the loss of appetite, respectively, because of smoking. There was a significant relationship between dietary diversity and the occurrence of several diseases such as gastric problems, nausea and loss of appetite. The respondents who consumed fresh fruits and vegetables regularly might reduce gastric problems (OR: 0.53, 95% CI: 0.27–1.04 and OR: 0.64, 95% CI: 0.25–1.65), nausea (OR: 0.72, 95% CI: 0.38–1.37 and OR: 0.28, 95% CI: 0.13–0.84) and loss of appetite (OR: 0.52, 95% CI: 0.32–1.21 and OR: 0.16 95% CI: 0.27–0.68).\u0000\u0000\u0000Originality/value\u0000In conclusion, smoking has been associated with multiple health problems because of poor practices score. Consumption of a balanced diet, better smoking-related knowledge, attitudes and practices needs to be improved among adolescents.\u0000","PeriodicalId":19376,"journal":{"name":"Nutrition & Food Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48918142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phytochemical screening and evaluation of the anti-diarrhoea properties of Diodia sarmentosa leaves in castor oil-induced diarrhoea in albino rats 蓖麻油致白化病大鼠腹泻的植物化学筛选及对水刺叶抗腹泻特性的评价
IF 1.2 Q2 Agricultural and Biological Sciences Pub Date : 2021-08-05 DOI: 10.1108/nfs-03-2021-0093
Stanley Ifeanyi Anyanwu-Azuka, Gabriel Sunday Aloh, Winner O Kalu, C. Eleazu
PurposeThis study aims to report the phytochemical screening and anti-diarrhoea properties of methanol extract of Diodia sarmentosa Swartz (DSS) leave (at 200, 400 and 600 mg/kg) in albino rats.Design/methodology/approachThree types of diarrhoea models (castor oil-induced diarrhoea, castor oil-induced gastrointestinal motility and castor oil-induced enteropooling), as well as an assay for serum and faecal electrolyte concentrations, were used. Acute toxicity study and phytochemical screening of the extract were carried out using standard techniques.FindingsThe percentage inhibition of diarrhoea by DSS 200, 400 and 600 mg/kg was obtained as 25.7%, 55% and 84.6%, respectively, compared with loperamide that had 87.6% inhibition. DSS dose dependently modulated the number and frequency of defecation, the weight of the faeces of the diarrhoea rats, the distance that was travelled by charcoal meal, mean differences in the full lengths of the intestines and the distance travelled by charcoal meal, weight and volume of intestinal contents, serum and faecal concentrations of potassium, sodium, chloride, magnesium, bicarbonate, iron and zinc relative to the negative control and in a manner akin to loperamide (for the extract at 600 mg/kg). DSS or loperamide attenuated the loss of calcium in the faeces of the rats. DSS possesses anti-diarrhoea properties, which may be attributed to the phytochemicals in it. Finally, the study showed the safety in the usage of DSS.Originality/valueDSS exerted its anti-diarrhoea action in castor oil-induced diarrhoea rats, by modulating their intestinal secretory and motile activity in a manner akin to loperamide (for DSS at 600 mg/kg).
目的研究白化病大鼠200、400、600 mg/kg双荆叶甲醇提取物的植物化学筛选及抗腹泻作用。设计/方法/方法采用三种腹泻模型(蓖麻油致腹泻、蓖麻油致胃肠运动和蓖麻油致肠蠕动),并测定血清和粪便电解质浓度。采用标准技术对提取物进行急性毒性研究和植物化学筛选。结果DSS 200、400和600 mg/kg对腹泻的抑制率分别为25.7%、55%和84.6%,而洛哌丁胺的抑制率为87.6%。DSS剂量依赖性地调节了排便次数和频率,腹泻大鼠粪便的重量,炭粉传播的距离,肠道长度和炭粉传播距离的平均差异,肠道内容物的重量和体积,血清和粪便中钾,钠,氯化物,镁,碳酸氢盐的浓度,铁和锌相对于阴性对照,方法类似于洛哌丁胺(提取物为600 mg/kg)。DSS或洛哌丁胺减轻了大鼠粪便中钙的流失。DSS具有抗腹泻的特性,这可能归因于其中的植物化学物质。最后,研究表明了DSS使用的安全性。edss在蓖麻油诱导的腹泻大鼠中发挥抗腹泻作用,其作用方式类似于洛哌丁胺(DSS为600 mg/kg)调节肠道分泌和运动活性。
{"title":"Phytochemical screening and evaluation of the anti-diarrhoea properties of Diodia sarmentosa leaves in castor oil-induced diarrhoea in albino rats","authors":"Stanley Ifeanyi Anyanwu-Azuka, Gabriel Sunday Aloh, Winner O Kalu, C. Eleazu","doi":"10.1108/nfs-03-2021-0093","DOIUrl":"https://doi.org/10.1108/nfs-03-2021-0093","url":null,"abstract":"\u0000Purpose\u0000This study aims to report the phytochemical screening and anti-diarrhoea properties of methanol extract of Diodia sarmentosa Swartz (DSS) leave (at 200, 400 and 600 mg/kg) in albino rats.\u0000\u0000\u0000Design/methodology/approach\u0000Three types of diarrhoea models (castor oil-induced diarrhoea, castor oil-induced gastrointestinal motility and castor oil-induced enteropooling), as well as an assay for serum and faecal electrolyte concentrations, were used. Acute toxicity study and phytochemical screening of the extract were carried out using standard techniques.\u0000\u0000\u0000Findings\u0000The percentage inhibition of diarrhoea by DSS 200, 400 and 600 mg/kg was obtained as 25.7%, 55% and 84.6%, respectively, compared with loperamide that had 87.6% inhibition. DSS dose dependently modulated the number and frequency of defecation, the weight of the faeces of the diarrhoea rats, the distance that was travelled by charcoal meal, mean differences in the full lengths of the intestines and the distance travelled by charcoal meal, weight and volume of intestinal contents, serum and faecal concentrations of potassium, sodium, chloride, magnesium, bicarbonate, iron and zinc relative to the negative control and in a manner akin to loperamide (for the extract at 600 mg/kg). DSS or loperamide attenuated the loss of calcium in the faeces of the rats. DSS possesses anti-diarrhoea properties, which may be attributed to the phytochemicals in it. Finally, the study showed the safety in the usage of DSS.\u0000\u0000\u0000Originality/value\u0000DSS exerted its anti-diarrhoea action in castor oil-induced diarrhoea rats, by modulating their intestinal secretory and motile activity in a manner akin to loperamide (for DSS at 600 mg/kg).\u0000","PeriodicalId":19376,"journal":{"name":"Nutrition & Food Science","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2021-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45641517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
Nutrition & Food Science
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1