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Orbital Causes of Ostiomeatal Complex Occlusion. 口鼻道复合体闭塞的眼眶原因。
IF 1.3 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2025-06-06 DOI: 10.1097/IOP.0000000000002965
Marissa K Shoji, Eman Al-Sharif, Nahia Dib El Jalbout, Akshara R Legala, Carol H Yan, Catherine Y Liu, Bobby S Korn, Don O Kikkawa

Purpose: This study aimed to describe uncommon cases of ostiomeatal complex (OMC) occlusion and maxillary atelectasis secondary to orbital pathology.

Methods: A retrospective chart review of cases of ostiomeatal occlusion and maxillary atelectasis at a single institution was performed. Patients with an identifiable orbital cause were included, whereas patients with idiopathic occlusion (silent sinus syndrome) were excluded. Data collected included patient age, sex, clinical presentation, and measurements including exophthalmolmetry, radiographic features, interventions, and outcomes.

Results: Eight patients were identified with mechanical causes of ostiomeatal occlusion arising from the orbit. Five cases had malpositioned orbital floor implants in the setting of remote orbital reconstruction, including after trauma. Two cases had previous orbital decompression for thyroid eye disease with subsequent orbital mucocele and fat prolapse into the OMC. One case had distensible venous malformation of the inferior orbit resulting in occlusion of the OMC. The majority of patients required both endoscopic sinus surgery and treatment of the orbital pathology causing the OMC occlusion.

Conclusions: While rare, orbital pathology may cause OMC occlusion, which may lead to maxillary sinus atelectasis. Orbital surgeons should be aware of these associations and have a high index of suspicion when subclinical maxillary atelectasis is seen in conjunction with orbital pathology. Treatment may require addressing the underlying cause as well as multidisciplinary management of both sinus surgery to restore maxillary sinus ventilation and possible orbital reconstruction.

目的:本研究的目的是描述罕见病例口鼻道复合体(OMC)闭塞和上颌不张继发于眼眶病理。方法:对同一医院的口鼻道闭塞和上颌不张病例进行回顾性分析。有明确眼眶病因的患者被纳入研究,而有特发性闭塞(无症状鼻窦综合征)的患者被排除在外。收集的数据包括患者的年龄、性别、临床表现和测量指标,包括眼球测量、放射学特征、干预措施和结果。结果:确定了8例由眶部引起的口鼻道阻塞的机械原因。5例眶底植入物在远程眶重建术中移位,包括外伤后。2例因甲状腺眼病行眼窝减压术,并发眼窝黏液囊肿及脂肪脱出至眶黏膜。1例下眶静脉膨大畸形导致眶内眶膜阻塞。大多数患者需要鼻窦内窥镜手术和眼眶病理治疗引起的OMC闭塞。结论:虽然罕见,但眼窝病理可引起上颌窦闭锁,导致上颌窦不张。眶外科医生应该意识到这些关联,当亚临床上颌不张与眶病理相结合时,应高度怀疑。治疗可能需要解决潜在的原因,以及窦手术的多学科管理,以恢复上颌窦通气和可能的眶重建。
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引用次数: 0
Modulation of Intraocular Pressure Following Short-Term Periocular Triamcinolone 0.025% in Oculoplastic Surgery. 0.025%短期眼周曲安奈德对眼压的调节作用。
IF 1.3 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2025-05-13 DOI: 10.1097/IOP.0000000000002966
Fereshteh Azad, Lauren D Mileo, Nicole Oska, Robert Beaulieu, Dianne Schlachter, Evan H Black

Purpose: Corticosteroid use is commonly associated with an increase in intraocular pressure (IOP). Our retrospective study aims to evaluate the effect of short-term periocular topical triamcinolone acetonide (TA) use on IOP.

Methods: A retrospective review was conducted of patients treated with periocular 0.025% triamcinolone cream between 2023 and 2024 at a single specialty practice. Patients with baseline and follow-up IOP assessments at their visits were included. Factors such as age, dosage, procedure type, application site, and concomitant TA and 5-fluorouracil (5-FU) subcutaneous injections or neomycin-polymyxin B-dexamethasone drops were analyzed.

Results: A total of 62 patients involving 120 eyes met the inclusion criteria. The overall mean change in IOP (14.35 to 14.32 mm Hg) was not statistically significant ( t = 0.085, p = 0.93). IOP did not significantly increase with age ( r = 0.16, p = 0.21), once daily ( B = -3.3, p = 0.13), or twice daily dosing ( B = -3.5, p = 0.26), nor with concomitant TA and 5-FU injection ( B = -1.5, p = 0.40) or topical steroid drops ( B = -1.5, p = 0.26). Procedure type was not associated with significant IOP changes, specifically upper eyelid blepharoplasty ( B = 0.76, p = 0.39), CO 2 laser resurfacing ( B = 1.2, p = 0.39), and lower eyelid blepharoplasty ( B = 1.9, p = 0.14). Application of TA to the bilateral upper eyelids caused a significant increase in IOP of 1.7 mm Hg ( t = 3.7, p = 0.003), but the maximum IOP was within the normal range (16 mm Hg).

Conclusions: Periocular application of TA cream is not associated with clinically significant changes in IOP when used for limited periods of time.

目的:皮质类固醇的使用通常与眼压(IOP)升高有关。我们的回顾性研究旨在评估短期眼周局部使用曲安奈德(TA)对IOP的影响。方法:回顾性分析2023年至2024年在某一专科使用0.025%曲安奈德乳膏治疗的患者。患者就诊时进行基线和随访IOP评估。分析年龄、剂量、程序类型、应用部位、TA和5-氟尿嘧啶(5-FU)皮下注射或新霉素-多粘菌素b -地塞米松滴剂等因素。结果:62例患者共120只眼符合纳入标准。总体平均眼压变化(14.35 ~ 14.32 mm Hg)无统计学意义(t = 0.085, p = 0.93)。IOP没有随着年龄(r = 0.16, p = 0.21)、每日一次(B = -3.3, p = 0.13)或每日两次给药(B = -3.5, p = 0.26)而显著增加,也没有与TA和5-FU同时注射(B = -1.5, p = 0.40)或外用类固醇滴剂(B = -1.5, p = 0.26)同时增加。手术类型与IOP变化无关,特别是上睑成形术(B = 0.76, p = 0.39)、CO2激光置换(B = 1.2, p = 0.39)和下睑成形术(B = 1.9, p = 0.14)。双侧上眼睑应用TA可使IOP显著升高1.7 mm Hg (t = 3.7, p = 0.003),但最大IOP在正常范围内(16 mm Hg)。结论:当在有限的时间内使用TA霜时,眼周应用与IOP的临床显著变化无关。
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引用次数: 0
Squamous Cell Carcinoma of the Lacrimal Sac Presenting as Ptosis. 泪囊鳞状细胞癌表现为上睑下垂。
IF 1.3 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2025-07-28 DOI: 10.1097/IOP.0000000000003006
Grace Tu, Sasha Hubschman, Ann Q Tran, Pete Setabutr
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引用次数: 0
Acute Exacerbation of the Orbital Angioleiomyoma With Hemodynamic Changes. 眼眶血管平滑肌瘤急性发作伴血流动力学改变。
IF 1.3 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2025-08-11 DOI: 10.1097/IOP.0000000000002996
Dongyoung Lee, Keon Ha Kim, Kyung In Woo

A 58-year-old woman presented with progressive proptosis and intermittent eye pain. Imaging showed an orbital mass with a central thrombus, initially suspected as a thrombosed venous malformation. However, rapid symptom worsening with visual loss necessitated further evaluation. Transfemoral cerebral angiography demonstrated a vascular mass supplied by the ophthalmic artery with venous drainage to the cavernous sinus, suggesting an arteriovenous malformation. The patient underwent transvenous embolization followed by surgical excision. Histopathological examination confirmed angioleiomyoma with thrombus formation. This case highlights a rare presentation of orbital angioleiomyoma with acute exacerbation due to hemodynamic changes. The combined approach of embolization and surgical resection proved effective in managing the orbital tumor, reducing complications, and achieving complete resolution of symptoms.

一名58岁女性,表现为进行性眼球突出和间歇性眼痛。影像学显示眼眶肿块伴中心血栓,最初怀疑为血栓性静脉畸形。然而,症状迅速恶化并视力下降需要进一步评估。经股脑血管造影显示一血管团块由眼动脉供应,静脉引流至海绵窦,提示动静脉畸形。患者接受经静脉栓塞后手术切除。组织病理学检查证实血管平滑肌瘤伴血栓形成。本病例为罕见的眼眶血管平滑肌瘤,因血流动力学改变而急性加重。栓塞和手术切除相结合的方法在治疗眼眶肿瘤,减少并发症和完全解决症状方面是有效的。
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引用次数: 0
Re: "Eyelid Retraction Following Combined Frontalis Flap and Levator Advancement Surgery". 回复:“额肌瓣联合提上提肌手术后眼睑缩回”。
IF 1.3 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2026-01-05 DOI: 10.1097/IOP.0000000000003113
Mostafa M Diab
{"title":"Re: \"Eyelid Retraction Following Combined Frontalis Flap and Levator Advancement Surgery\".","authors":"Mostafa M Diab","doi":"10.1097/IOP.0000000000003113","DOIUrl":"https://doi.org/10.1097/IOP.0000000000003113","url":null,"abstract":"","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":"42 1","pages":"e27-e28"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145906336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply Re: "Progress of Baggy Eyelid: An Anatomical Study". 回复:“眼睑松弛的解剖学研究进展”。
IF 1.3 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2026-01-05 DOI: 10.1097/IOP.0000000000003123
Hirohiko Kakizaki
{"title":"Reply Re: \"Progress of Baggy Eyelid: An Anatomical Study\".","authors":"Hirohiko Kakizaki","doi":"10.1097/IOP.0000000000003123","DOIUrl":"https://doi.org/10.1097/IOP.0000000000003123","url":null,"abstract":"","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":"42 1","pages":"e33"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145906337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Re: "A Safer and Easier Method to Open the Orbital Septum: Septal Ballooning". 回复:“一种更安全、更容易打开眶隔的方法:鼻中隔球囊术”。
IF 1.3 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2026-01-05 DOI: 10.1097/IOP.0000000000003124
Mostafa M Diab
{"title":"Re: \"A Safer and Easier Method to Open the Orbital Septum: Septal Ballooning\".","authors":"Mostafa M Diab","doi":"10.1097/IOP.0000000000003124","DOIUrl":"https://doi.org/10.1097/IOP.0000000000003124","url":null,"abstract":"","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":"42 1","pages":"e33-e34"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145906358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply Re: "A Safer and Easier Method to Open the Orbital Septum: Septal Ballooning". 回复:“一种更安全、更容易打开眶隔的方法:鼻中隔球囊术”。
IF 1.3 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2026-01-05 DOI: 10.1097/IOP.0000000000003125
Junghoon Kim, Yeshins Kim, Kyung In Woo
{"title":"Reply Re: \"A Safer and Easier Method to Open the Orbital Septum: Septal Ballooning\".","authors":"Junghoon Kim, Yeshins Kim, Kyung In Woo","doi":"10.1097/IOP.0000000000003125","DOIUrl":"https://doi.org/10.1097/IOP.0000000000003125","url":null,"abstract":"","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":"42 1","pages":"e34-e35"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145906377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pericranial Flaps and Grafts for Oculoplastic Reconstructive Surgery: A Major Review. 颅周皮瓣和移植物用于眼部整形重建手术:主要综述。
IF 1.3 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2025-06-09 DOI: 10.1097/IOP.0000000000002980
Sugi Panneerselvam, Marissa K Shoji, Benyam Kinde, Brian C Tse, David T Tse

Purpose: The pericranium, a component often overlooked in oculoplastic surgery, is a rich source of reconstructive potential. While it is frequently used in craniofacial surgery, pericranial flaps and grafts are generally underutilized in oculoplastics, with limited published research. This review aims to highlight its anatomy, surgical dissection techniques, and versatile benefits to inspire and motivate the oculoplastic community to widen its application in reconstructive surgery.

Methods: A literature review of all cases published in oculoplastic surgery using pericranial flaps.

Results: The anatomy, operative dissection methods, and all published applications of pericranial flaps and free grafts in oculoplastic surgery are described. Vascularized flaps have been used to reconstruct eyelid and orbital defects, frontal-orbital mucoceles, and orbital-sinus fistulas. Free pericranial grafts are less frequently reported in oculoplastic literature, as they are primarily used in conjunction with a vascularized cutaneous flap for eyelid defects, but may also be used alone in the repair of forniceal contraction or cases of implant exposure.

Conclusions: This review underscores the significant potential of pericranial tissue for oculoplastic reconstruction. Its advantages over existing autologous reconstructive tissues, including maintaining the integrity of overlying skin and soft tissue, rich vascularity, and convenient proximity to periocular and facial defects, make it a promising option for eyelid reconstruction. While isolating the flap may be technically challenging, pericranial flaps and grafts can significantly improve functional and cosmetic outcomes in oculoplastic reconstruction.

目的:在眼部整形手术中经常被忽视的一个组成部分是一个丰富的重建潜力来源。虽然颅面外科经常使用颅周皮瓣和移植物,但在眼部整形术中通常未充分利用,发表的研究有限。本文就其解剖结构、手术解剖技术及其多方面的益处进行综述,以期启发和推动眼科整形界扩大其在重建手术中的应用。方法:对所有采用颅周皮瓣进行眼部整形手术的病例进行文献回顾。结果:介绍了颅周皮瓣和游离移植物在眼部整形手术中的解剖、手术解剖方法和所有已发表的应用。血管化皮瓣已被用于重建眼睑和眼眶缺损、额眶黏液囊肿和眼眶窦瘘。游离颅周移植物在眼整形文献中较少报道,因为它们主要与带血管的皮瓣联合用于眼睑缺损,但也可以单独用于修复穹窿收缩或植入物暴露的情况。结论:本综述强调了颅周组织在眼成形术重建中的重要潜力。与现有的自体重建组织相比,其优点包括保持覆盖皮肤和软组织的完整性,丰富的血管,方便靠近眼周和面部缺陷,使其成为眼睑重建的有希望的选择。虽然分离皮瓣在技术上可能具有挑战性,但颅周皮瓣和移植物可以显著改善眼成形术重建的功能和美容效果。
{"title":"Pericranial Flaps and Grafts for Oculoplastic Reconstructive Surgery: A Major Review.","authors":"Sugi Panneerselvam, Marissa K Shoji, Benyam Kinde, Brian C Tse, David T Tse","doi":"10.1097/IOP.0000000000002980","DOIUrl":"10.1097/IOP.0000000000002980","url":null,"abstract":"<p><strong>Purpose: </strong>The pericranium, a component often overlooked in oculoplastic surgery, is a rich source of reconstructive potential. While it is frequently used in craniofacial surgery, pericranial flaps and grafts are generally underutilized in oculoplastics, with limited published research. This review aims to highlight its anatomy, surgical dissection techniques, and versatile benefits to inspire and motivate the oculoplastic community to widen its application in reconstructive surgery.</p><p><strong>Methods: </strong>A literature review of all cases published in oculoplastic surgery using pericranial flaps.</p><p><strong>Results: </strong>The anatomy, operative dissection methods, and all published applications of pericranial flaps and free grafts in oculoplastic surgery are described. Vascularized flaps have been used to reconstruct eyelid and orbital defects, frontal-orbital mucoceles, and orbital-sinus fistulas. Free pericranial grafts are less frequently reported in oculoplastic literature, as they are primarily used in conjunction with a vascularized cutaneous flap for eyelid defects, but may also be used alone in the repair of forniceal contraction or cases of implant exposure.</p><p><strong>Conclusions: </strong>This review underscores the significant potential of pericranial tissue for oculoplastic reconstruction. Its advantages over existing autologous reconstructive tissues, including maintaining the integrity of overlying skin and soft tissue, rich vascularity, and convenient proximity to periocular and facial defects, make it a promising option for eyelid reconstruction. While isolating the flap may be technically challenging, pericranial flaps and grafts can significantly improve functional and cosmetic outcomes in oculoplastic reconstruction.</p>","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":" ","pages":"19-27"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144249040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patterns of Basal Cell Carcinoma Presentation in the NIH All of Us Database. NIH所有人数据库中基底细胞癌的表现模式。
IF 1.3 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2025-06-20 DOI: 10.1097/IOP.0000000000002979
Sarah Cheng, Kelsey A Roelofs

Purpose: To examine risk factors for the development of eyelid, face, and body basal cell carcinoma (BCC) within the National Institutes of Health All of Us database.

Methods: Around 7342 patients with BCC and 29,728 age-matched controls were included. Patients with genetic syndromes predisposing to BCC, and patients with a history of solid organ transplants were excluded. Outcomes examined included tumor location, ethnicity, age, smoking, alcohol intake, income, and access to care. Univariate and multivariate regression analyses were performed to examine the association between BCC on different areas of the body and race as well as the effect of modifiable risk factors.

Results: Almost 48.7% (3623) of patients had BCC on the body (nonface), 47.2% had BCC on the face (3505), and 4.1% (304) had BCC of the eyelid. White race (OR, 11.79; CI, 5.99-27.73; p < 0.001) and male sex (OR, 1.23; CI, 1.14-1.33; p < 0.001) were nonmodifiable risk factors for BCC and overall, patients with facial BCC were significantly older ( p < 0.001) than those with body BCC. Nonwhite patients with BCC were younger, and significantly more likely to have nonfacial BCC ( p < 0.001). On multivariate analysis, alcohol intake also showed a dose-dependent increased risk for BCC (OR, 1.54; CI, 1.14-2.13; p < 0.001) of the face.

Conclusions: Nonwhite patients were significantly younger and more likely to be diagnosed with nonfacial BCC. Thus, we hypothesize that BCC pathogenesis may not be as closely related to cumulative sun exposure as for white patients. Alcohol intake is an important modifiable risk factor.

目的:在美国国立卫生研究院的All of Us数据库中研究眼睑、面部和身体基底细胞癌(BCC)发展的危险因素。方法:纳入约7342例BCC患者和29728例年龄匹配的对照组。排除了易患BCC的遗传综合征患者和有实体器官移植史的患者。检查的结果包括肿瘤位置、种族、年龄、吸烟、饮酒、收入和获得护理的机会。采用单因素和多因素回归分析来检验BCC在身体不同部位和种族之间的关系以及可改变的危险因素的影响。结果:近48.7%(3623人)的患者有BCC出现在身体(非面部),47.2%(3505人)有BCC出现在面部,4.1%(304人)有BCC出现在眼睑。白种人(OR, 11.79;CI, 5.99 - -27.73;p < 0.001)和男性性别(OR, 1.23;CI, 1.14 - -1.33;p < 0.001)是BCC的不可改变的危险因素,总体而言,面部BCC患者明显比身体BCC患者年龄大(p < 0.001)。非白人BCC患者更年轻,非面部BCC的可能性更大(p < 0.001)。在多变量分析中,酒精摄入也显示出剂量依赖性的BCC风险增加(OR, 1.54;CI, 1.14 - -2.13;P < 0.001)。结论:非白人患者明显更年轻,更容易被诊断为非面部基底细胞癌。因此,我们假设BCC的发病机制可能不像白人患者那样与日晒密切相关。酒精摄入是一个重要的可改变的危险因素。
{"title":"Patterns of Basal Cell Carcinoma Presentation in the NIH All of Us Database.","authors":"Sarah Cheng, Kelsey A Roelofs","doi":"10.1097/IOP.0000000000002979","DOIUrl":"10.1097/IOP.0000000000002979","url":null,"abstract":"<p><strong>Purpose: </strong>To examine risk factors for the development of eyelid, face, and body basal cell carcinoma (BCC) within the National Institutes of Health All of Us database.</p><p><strong>Methods: </strong>Around 7342 patients with BCC and 29,728 age-matched controls were included. Patients with genetic syndromes predisposing to BCC, and patients with a history of solid organ transplants were excluded. Outcomes examined included tumor location, ethnicity, age, smoking, alcohol intake, income, and access to care. Univariate and multivariate regression analyses were performed to examine the association between BCC on different areas of the body and race as well as the effect of modifiable risk factors.</p><p><strong>Results: </strong>Almost 48.7% (3623) of patients had BCC on the body (nonface), 47.2% had BCC on the face (3505), and 4.1% (304) had BCC of the eyelid. White race (OR, 11.79; CI, 5.99-27.73; p < 0.001) and male sex (OR, 1.23; CI, 1.14-1.33; p < 0.001) were nonmodifiable risk factors for BCC and overall, patients with facial BCC were significantly older ( p < 0.001) than those with body BCC. Nonwhite patients with BCC were younger, and significantly more likely to have nonfacial BCC ( p < 0.001). On multivariate analysis, alcohol intake also showed a dose-dependent increased risk for BCC (OR, 1.54; CI, 1.14-2.13; p < 0.001) of the face.</p><p><strong>Conclusions: </strong>Nonwhite patients were significantly younger and more likely to be diagnosed with nonfacial BCC. Thus, we hypothesize that BCC pathogenesis may not be as closely related to cumulative sun exposure as for white patients. Alcohol intake is an important modifiable risk factor.</p>","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":" ","pages":"40-44"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144333645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Ophthalmic Plastic and Reconstructive Surgery
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