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4CPS-080 Optimisation of antiretroviral therapy: results after simplification to bitherapy with dolutegravir/lamivudine or dolutegravir/rilpivirine 优化抗逆转录病毒治疗:简化为多替格拉韦/拉米夫定或多替格拉韦/利匹韦林双药治疗后的结果
Pub Date : 2023-03-01 DOI: 10.1136/ejhpharm-2023-eahp.389
MJ Canalejo Fuentes, N. Herrero Muñoz, A. Ontañón Nasarre, M. García Gil
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引用次数: 0
4CPS-112 Survey of dietary supplement use and vaccination status among rheumatoid arthritis patients during the COVID-19 pandemic 4CPS-112新冠肺炎大流行期间类风湿关节炎患者膳食补充剂使用和疫苗接种状况调查
Pub Date : 2023-03-01 DOI: 10.1136/ejhpharm-2023-eahp.399
R. Vida, M. Auer, M. Jancsó, N. Schaadt, A. Somogyi-Végh, L. Botz
Background and ImportanceIn recent years not just the novel therapeutic approaches, but the Coronavirus pandemic has also affected the therapy management of patients with rheumatoid arthritis. Beside these changes, the immunisation against COVID-19 has also been an issue and raised several questions from clinicians to patients.Aim and ObjectivesTherefore, our aim was to find out the possible changes that patients were experiencing and the potential factors influencing their therapy.Material and MethodsData was collected through structured personal interviews with a 33-item questionnaire licensed by the Regional Research Ethics Committee of the University of Pécs and review of the medical records from January until September in 2022. We used the data available in the ambulatory medical records and the itemised reporting interface of the National Health Insurance Fund. Drug interactions were analysed using UpToDate Lexicomp database.Results35 female patients (average age: 63.53 years ± 13.82) and 23 male patients (average age: 53.54 ± 12.96) received biological or targeted therapy for an average of 7.17 years ( ± 4.12), while the average patient activity index DAS28 was 3.15 ( ± 1.17) and BASDAI was 5.29 ( ± 5.52). 87.93% (51/58) of the patients have used non-medication health products, mainly vitamin C or D. 34.48% of the patients were confirmed with coronavirus infection during the pandemic, while the vaccination rate was 87.89%. 83.45% of the patients received at least one mRNA vaccine. In our patient group, the influenza vaccination rate was 36.21%, while only 5.21% of the patients had been vaccinated against Pneumococcus in six months previous to our survey. The total number of serious (category X and D) interactions were 216, in 135 cases a vaccine and in 58 cases a monoclonal antibody or targeted therapy was included as interacting pair.Conclusion and RelevanceDespite the growing number of new therapeutic approaches and vaccines, the screening methods for analysing potential drug interaction are lacking behind and the Summary of Product Characteristics are not suitable for comprehensive evaluations. The inclusion of these therapies and the optimisation in vaccination status in the medication review process and the understanding of immunological mechanism potentially influencing the therapy of patients is warranted.References and/or AcknowledgementsConflict of InterestNo conflict of interest
背景与重要性近年来,除了新的治疗方法外,冠状病毒大流行也影响了类风湿关节炎患者的治疗管理。除了这些变化,针对COVID-19的免疫接种也是一个问题,从临床医生到患者都提出了几个问题。因此,我们的目的是找出患者可能经历的变化以及影响其治疗的潜在因素。材料和方法通过结构化的个人访谈收集数据,调查问卷由psamacs大学区域研究伦理委员会许可,共33项,并审查了2022年1月至9月的医疗记录。我们使用了流动医疗记录和国家健康保险基金的分项报告界面中的可用数据。使用UpToDate Lexicomp数据库分析药物相互作用。结果35例女性患者(平均年龄:63.53岁±13.82岁)和23例男性患者(平均年龄:53.54±12.96岁)接受生物或靶向治疗,平均7.17年(±4.12年),患者平均活动指数DAS28为3.15(±1.17),BASDAI为5.29(±5.52)。87.93%(51/58)的患者使用过非药物类保健品,主要为维生素C或d。34.48%的患者在疫情期间确诊为冠状病毒感染,而疫苗接种率为87.89%。83.45%的患者接种了至少一种mRNA疫苗。在我们的患者组中,流感疫苗接种率为36.21%,而在我们调查前6个月内,只有5.21%的患者接种过肺炎球菌疫苗。严重(X类和D类)相互作用的总数为216例,其中135例疫苗和58例单克隆抗体或靶向治疗被列为相互作用对。结论与相关性尽管新的治疗方法和疫苗不断涌现,但分析潜在药物相互作用的筛选方法尚不完善,《产品特性总结》也不适合进行综合评价。在药物审查过程中纳入这些疗法和优化疫苗接种状态以及了解可能影响患者治疗的免疫机制是有必要的。参考文献和/或致谢利益冲突无利益冲突
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引用次数: 0
6ER-003 The climate emergency, how can pharmacy make a difference? 气候紧急情况,药剂学如何发挥作用?
Pub Date : 2023-03-01 DOI: 10.1136/ejhpharm-2023-eahp.464
R. O'Hare, S. Gilespie, S. Haughey
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引用次数: 0
3PC-030 Evaluation of excipients used in paediatric compounded formulations prescribed in a neonatal intensive care unit 新生儿重症监护室处方的儿科复方制剂中使用的赋形剂的评价
Pub Date : 2023-03-01 DOI: 10.1136/ejhpharm-2023-eahp.370
R. Barbosa, S. Fraga, C. Sampaio, L. Sousa, P. Soares, C. Barbosa
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引用次数: 0
6ER-012 Treatment decisions according to 1-year risk mortality in pulmonary arterial hypertension patients: a multicentre retrospective study 根据肺动脉高压患者1年死亡风险的治疗决定:一项多中心回顾性研究
Pub Date : 2023-03-01 DOI: 10.1136/ejhpharm-2023-eahp.466
H. Rodríguez-Ramallo, N. Báez Gutiérrez, B. Aparicio Castellano, A. Rodríguez Pérez, B. Santos Ramos, L. Rodríguez Defrancisco, M. Fernández González
{"title":"6ER-012 Treatment decisions according to 1-year risk mortality in pulmonary arterial hypertension patients: a multicentre retrospective study","authors":"H. Rodríguez-Ramallo, N. Báez Gutiérrez, B. Aparicio Castellano, A. Rodríguez Pérez, B. Santos Ramos, L. Rodríguez Defrancisco, M. Fernández González","doi":"10.1136/ejhpharm-2023-eahp.466","DOIUrl":"https://doi.org/10.1136/ejhpharm-2023-eahp.466","url":null,"abstract":"","PeriodicalId":19619,"journal":{"name":"Oral Presentations - Late-Breaking Proffered Abstracts","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73310305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
4CPS-035 Association of dihydropyrimidine dehydrogenase deficiency with capecitabine tolerance 二氢嘧啶脱氢酶缺乏与卡培他滨耐受性的关系
Pub Date : 2023-03-01 DOI: 10.1136/ejhpharm-2023-eahp.380
A. Peláez Bejarano, E. Rodrigues Molins, L. Gómez-Sayago
{"title":"4CPS-035 Association of dihydropyrimidine dehydrogenase deficiency with capecitabine tolerance","authors":"A. Peláez Bejarano, E. Rodrigues Molins, L. Gómez-Sayago","doi":"10.1136/ejhpharm-2023-eahp.380","DOIUrl":"https://doi.org/10.1136/ejhpharm-2023-eahp.380","url":null,"abstract":"","PeriodicalId":19619,"journal":{"name":"Oral Presentations - Late-Breaking Proffered Abstracts","volume":"115 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79114916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
5PSQ-126 Effectiveness and safety of omalizumab, mepolizumab and benralizumab in patients with severe uncontrolled asthma omalizumab、mepolizumab和benralizumab在严重未控制哮喘患者中的有效性和安全性
Pub Date : 2023-03-01 DOI: 10.1136/ejhpharm-2023-eahp.458
V. González Rosa, AB Morillo Mora, C. Muñoz Cid, M. Zaragoza Rascón, J. González-Miret Martín
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引用次数: 0
4CPS-252 Optimisation of ertapenem posology in a critically ill patient by therapeutic drug monitoring: a case report 通过治疗药物监测优化厄他培南在危重患者中的应用:1例报告
Pub Date : 2023-03-01 DOI: 10.1136/ejhpharm-2023-eahp.432
A. Gracia Moya, S. Garcia Garcia, M. Miarons Font, JM Del Río Gutiérrez, A. Pau Parra, ML Perez Rodriguez, M. L. Lalueza Broto, M. G. Gorgas Torner
{"title":"4CPS-252 Optimisation of ertapenem posology in a critically ill patient by therapeutic drug monitoring: a case report","authors":"A. Gracia Moya, S. Garcia Garcia, M. Miarons Font, JM Del Río Gutiérrez, A. Pau Parra, ML Perez Rodriguez, M. L. Lalueza Broto, M. G. Gorgas Torner","doi":"10.1136/ejhpharm-2023-eahp.432","DOIUrl":"https://doi.org/10.1136/ejhpharm-2023-eahp.432","url":null,"abstract":"","PeriodicalId":19619,"journal":{"name":"Oral Presentations - Late-Breaking Proffered Abstracts","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80195467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
4CPS-001 Emicizumab in acquired haemophilia type A: a case report Emicizumab治疗获得性A型血友病1例
Pub Date : 2023-03-01 DOI: 10.1136/ejhpharm-2023-eahp.373
J. Esquivel Negrín, P. Joy Carmona, A. Martín López, MÁ Ocaña Gómez, M. Ríos De Paz, M. D. De Dios García, B. del Rosario García, EG Fernández López, T. Betancor García, J. Merino Alonso
{"title":"4CPS-001 Emicizumab in acquired haemophilia type A: a case report","authors":"J. Esquivel Negrín, P. Joy Carmona, A. Martín López, MÁ Ocaña Gómez, M. Ríos De Paz, M. D. De Dios García, B. del Rosario García, EG Fernández López, T. Betancor García, J. Merino Alonso","doi":"10.1136/ejhpharm-2023-eahp.373","DOIUrl":"https://doi.org/10.1136/ejhpharm-2023-eahp.373","url":null,"abstract":"","PeriodicalId":19619,"journal":{"name":"Oral Presentations - Late-Breaking Proffered Abstracts","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80323307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
4CPS-013 Treosulfan-based conditioning regimen for allogeneic haematopoietic stem cell transplantation in children with sickle cell disease: efficacy and safety 基于treosulan的调节方案用于镰状细胞病儿童异体造血干细胞移植:疗效和安全性
Pub Date : 2023-03-01 DOI: 10.1136/ejhpharm-2023-eahp.375
Á. Narrillos Moraza, E. González-Haba Peña, M. Sánchez Fresneda, C. Martínez Fernández-Llamazares, S. Manrique Rodríguez, I. Taladriz Sender, A. Herranz Alonso, M. Sanjurjo Sáez
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引用次数: 0
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Oral Presentations - Late-Breaking Proffered Abstracts
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