Pub Date : 2023-10-30DOI: 10.14238/pi63.5.2023.353-60
Sumardi F. Simanjuntak, Titis Prawitasari, Muzal Kadim, Teny Tjitra Sari, H. Gunardi, Yvan Vandenplas, B. Hegar
Background The COVID-19 pandemic necessitated the use of online schooling in order to comply with national and local lockdown guidelines. Online learning required students and teachers to adapt to a new method of schooling. The inability of adolescents to adapt to their environment can interfere with their psychosocial condition and become a risk factor for functional gastrointestinal disorders (FGID). Objective To determine the prevalence of FGID in adolescents and evaluate possible risk factors that existed during online learning. Methods This cross-sectional study was done in children aged 12-18 years who participated in online learning during the COVID-19 pandemic. The diagnosis of FGID was based on Rome IV criteria. Psychosocial problems were assessed using the Pediatric Symptom Checklist Questionnaire–17 (PSC-17) which includes internalization, externalization, and attention subscales. Subjects with a PSC-17 mixed subscale total score of >15 were considered as having an increased likelihood of having a behavioral health disorder. Data were collected by online questionnaires via Google Forms. Results Of 1,413 participants, 23% experienced FGID; of these, 32.6% had >2 FGID diagnostic criteria. Upon multivariate analysis, internalization psychosocial problems were the most common risk factors for FGID, followed by mixed subscale psychosocial problems, unstable internet connection, and not understanding of the material. ConclusionThe prevalence of FGID in adolescents in this study is 23%. Environmental and psychosocial conditions are interrelated as risk factors for FGID in adolescents during online learning in the COVID-19 pandemic.
{"title":"Functional gastrointestinal disorders in adolescents during online learning","authors":"Sumardi F. Simanjuntak, Titis Prawitasari, Muzal Kadim, Teny Tjitra Sari, H. Gunardi, Yvan Vandenplas, B. Hegar","doi":"10.14238/pi63.5.2023.353-60","DOIUrl":"https://doi.org/10.14238/pi63.5.2023.353-60","url":null,"abstract":"Background The COVID-19 pandemic necessitated the use of online schooling in order to comply with national and local lockdown guidelines. Online learning required students and teachers to adapt to a new method of schooling. The inability of adolescents to adapt to their environment can interfere with their psychosocial condition and become a risk factor for functional gastrointestinal disorders (FGID). Objective To determine the prevalence of FGID in adolescents and evaluate possible risk factors that existed during online learning. Methods This cross-sectional study was done in children aged 12-18 years who participated in online learning during the COVID-19 pandemic. The diagnosis of FGID was based on Rome IV criteria. Psychosocial problems were assessed using the Pediatric Symptom Checklist Questionnaire–17 (PSC-17) which includes internalization, externalization, and attention subscales. Subjects with a PSC-17 mixed subscale total score of >15 were considered as having an increased likelihood of having a behavioral health disorder. Data were collected by online questionnaires via Google Forms. Results Of 1,413 participants, 23% experienced FGID; of these, 32.6% had >2 FGID diagnostic criteria. Upon multivariate analysis, internalization psychosocial problems were the most common risk factors for FGID, followed by mixed subscale psychosocial problems, unstable internet connection, and not understanding of the material. ConclusionThe prevalence of FGID in adolescents in this study is 23%. Environmental and psychosocial conditions are interrelated as risk factors for FGID in adolescents during online learning in the COVID-19 pandemic.","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":"52 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139311336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-30DOI: 10.14238/pi63.5.2023.383-8
B. Medise, Maulana Okta Reza, Yoga Devaera, Amanda Soebadi, N. Chozie, Antonius H Pudjiadi
Background The asynchrony rapid phase of cognitive, physical and emotional development occurring in adolescence may result in various issues such as risk-taking behavior, psychosocial and emotional problems. School closure during the COVID-19 pandemic has caused a tremendous change in adolescent lifestyle and habits, including sleep patterns. causing added challenges to adolescents’ emotional and behavioral problems. Objective To identify the association between sleep disorders with emotional and behavioral problems during the COVID-19 pandemic in urban and rural adolescents. Methods We conducted a cross-sectional study among adolescents aged 12-18 years from November to December 2021 in two provinces, DKI Jakarta and Riau Islands. We recruited students consecutively from randomly selected junior and senior high schools. We used the Strengths and Difficulties Questionnaire (SDQ) and the Pittsburgh Sleep Quality Index (PSQI) to screen for emotional and behavioral problems and for sleep disorders, respectively. The questionnaires were sent electronically to each subject after obtaining parental consent. Results There were 400 subjects included in our study, of which 64% were female. The prevalences of COVID-19 amongst subjects in urban and rural areas were COVID-19 12.5% and 5.5%, respectively. Emotional and behavioral disorders as well as sleep disorders were more common in rural than urban areas (13 vs. 11.5% and 50.5% vs. 38%; P=0.012, respectively). Sleep disorders were associated with the SDQ subscales of emotional symptoms [PR 4.88 (95%CI 2.97 to 8.03); P<0.01), conduct problems [PR 3.71 (95%CI 1.53 to 9.04); P=0.02), hyperactivity/inattention [PR 6.05 (95%CI 2.58 to 16.17); P<0.01], and peer relationship problems [PR 3.28 (95%CI 1.33 to 8.09); P<0.01). Conclusion Sleep disorders among adolescents during COVID-19 pandemic were associated with emotional and behavioral problems. Adolescents who live in rural areas were more likely to have sleep disorders, emotional and behavioral problems.
{"title":"Effects of the COVID-19 pandemic on emotional and behavioral problems and sleep problems in adolescents","authors":"B. Medise, Maulana Okta Reza, Yoga Devaera, Amanda Soebadi, N. Chozie, Antonius H Pudjiadi","doi":"10.14238/pi63.5.2023.383-8","DOIUrl":"https://doi.org/10.14238/pi63.5.2023.383-8","url":null,"abstract":"Background The asynchrony rapid phase of cognitive, physical and emotional development occurring in adolescence may result in various issues such as risk-taking behavior, psychosocial and emotional problems. School closure during the COVID-19 pandemic has caused a tremendous change in adolescent lifestyle and habits, including sleep patterns. causing added challenges to adolescents’ emotional and behavioral problems. Objective To identify the association between sleep disorders with emotional and behavioral problems during the COVID-19 pandemic in urban and rural adolescents. Methods We conducted a cross-sectional study among adolescents aged 12-18 years from November to December 2021 in two provinces, DKI Jakarta and Riau Islands. We recruited students consecutively from randomly selected junior and senior high schools. We used the Strengths and Difficulties Questionnaire (SDQ) and the Pittsburgh Sleep Quality Index (PSQI) to screen for emotional and behavioral problems and for sleep disorders, respectively. The questionnaires were sent electronically to each subject after obtaining parental consent. Results There were 400 subjects included in our study, of which 64% were female. The prevalences of COVID-19 amongst subjects in urban and rural areas were COVID-19 12.5% and 5.5%, respectively. Emotional and behavioral disorders as well as sleep disorders were more common in rural than urban areas (13 vs. 11.5% and 50.5% vs. 38%; P=0.012, respectively). Sleep disorders were associated with the SDQ subscales of emotional symptoms [PR 4.88 (95%CI 2.97 to 8.03); P<0.01), conduct problems [PR 3.71 (95%CI 1.53 to 9.04); P=0.02), hyperactivity/inattention [PR 6.05 (95%CI 2.58 to 16.17); P<0.01], and peer relationship problems [PR 3.28 (95%CI 1.33 to 8.09); P<0.01). Conclusion Sleep disorders among adolescents during COVID-19 pandemic were associated with emotional and behavioral problems. Adolescents who live in rural areas were more likely to have sleep disorders, emotional and behavioral problems.","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":"66 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139310433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-26DOI: 10.14238/pi63.5.2023.328-34
Paediatrica Indonesiana, Ni Putu Veny, Kartika Yantie, Kadek Maharini, Eka Gunawijaya, Gusti Ayu, Trisna Windiani, Ni Putu, Veny Kartika, Yantie. Jl, Tukad Batanghari
Background Echocardiography procedures can cause fear and anxiety in children, especially at preschool age. Audiovisual distraction is a simple, harmless, and low-cost technique that does not interfere with the procedure. Objective To assess the effect of audiovisual distraction on the anxiety levels of children aged 2-5 years during echocardiography. Methods This quasi-experimental study included children aged 2-5 years who were admitted for echocardiography. Patients with hearing or visual impairment, Down syndrome, autism, or attention-deficit/hyperactivity disorder were excluded. We administered anxiety-reducing intervention in the form of cartoon audiovisual media shown on a ceiling-mounted television during the echocardiography procedure. Anxiety levels were assessed using the Visual Analogue Scale - Anxiety (VAS-A) before and after the intervention was given. We compared the subjects’ pre- and post-procedure VAS-A scores and heart rates. Results Of the 43 subjects who underwent echocardiography during the study period, the mean age was 3.2 (SD 0.9) years, with an equal sex distribution. Most subjects had a history of repeated echocardiography procedures and hospitalizations. Thirty-nine (90.6%) of subjects demonstrated anxiety during the echocardiography procedure. There was a significant mean difference of 11.9 (SD 13.2) bpm (95%CI 7.8 to 15.9 bpm, p<0.001) in heart rate pre- vs. post-intervention. Median pre- and post-intervention VAS-A scores were 5 (range 0-10) and 1 (range 0-4), respectively (P=0.001). Post-intervention, almost all (97.7%) subjects had no or mild anxiety. Conclusion Audiovisual content presented on television serves as an effective distraction method to reduce children's anxiety during echocardiography.
{"title":"The efficacy of audiovisual distraction as an anxiety-minimizing technique during echocardiography in preschool children","authors":"Paediatrica Indonesiana, Ni Putu Veny, Kartika Yantie, Kadek Maharini, Eka Gunawijaya, Gusti Ayu, Trisna Windiani, Ni Putu, Veny Kartika, Yantie. Jl, Tukad Batanghari","doi":"10.14238/pi63.5.2023.328-34","DOIUrl":"https://doi.org/10.14238/pi63.5.2023.328-34","url":null,"abstract":"Background Echocardiography procedures can cause fear and anxiety in children, especially at preschool age. Audiovisual distraction is a simple, harmless, and low-cost technique that does not interfere with the procedure. Objective To assess the effect of audiovisual distraction on the anxiety levels of children aged 2-5 years during echocardiography. Methods This quasi-experimental study included children aged 2-5 years who were admitted for echocardiography. Patients with hearing or visual impairment, Down syndrome, autism, or attention-deficit/hyperactivity disorder were excluded. We administered anxiety-reducing intervention in the form of cartoon audiovisual media shown on a ceiling-mounted television during the echocardiography procedure. Anxiety levels were assessed using the Visual Analogue Scale - Anxiety (VAS-A) before and after the intervention was given. We compared the subjects’ pre- and post-procedure VAS-A scores and heart rates. Results Of the 43 subjects who underwent echocardiography during the study period, the mean age was 3.2 (SD 0.9) years, with an equal sex distribution. Most subjects had a history of repeated echocardiography procedures and hospitalizations. Thirty-nine (90.6%) of subjects demonstrated anxiety during the echocardiography procedure. There was a significant mean difference of 11.9 (SD 13.2) bpm (95%CI 7.8 to 15.9 bpm, p<0.001) in heart rate pre- vs. post-intervention. Median pre- and post-intervention VAS-A scores were 5 (range 0-10) and 1 (range 0-4), respectively (P=0.001). Post-intervention, almost all (97.7%) subjects had no or mild anxiety. Conclusion Audiovisual content presented on television serves as an effective distraction method to reduce children's anxiety during echocardiography.","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":"104 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139313555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-23DOI: 10.14238/pi63.5.2023.370-5
F. Alatas, Cholifatun Nisa
Background Cholestasis can lead to several complications, including portal hypertension and risk of gastrointestinal bleeding. However, there is a paucity of studies on the risk factors and prevalence of gastrointestinal tract bleeding in children with chronic cholestasis, particularly in Indonesia. Objective To determine the prevalence and risk factors for gastrointestinal bleeding in children with chronic cholestasis in Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Methods This was a retrospective cohort study in a national referral hospital in Indonesia. Medical records of children with chronic cholestasis who visited the gastroenterohepatology outpatient clinic were collected for five years. Data on clinical symptoms, etiologies, and complications were obtained. Results A total of 97 participants were recruited on this study. The median age of the group was 0.31 years old. The most common causes of chornic cholestasis were biliary atresia, toxoplasma, other infections, rubella, cytomegalovirus, and herpes simplex virus (TORCH) infection, and urinary tract infection. Gastrointestinal bleeding occurred in 27.8% of patients, with hematemesis-melena being the most prevalent symptom. We found that liver cirrhosis, splenomegaly, thrombocytopenia, portal hypertension, and esophageal varices were all highly related with gastrointestinal bleeding. Splenomegaly, thrombocytopenia, and esophageal varices were associated with an increased risk of gastrointestinal bleeding in children with chronic cholestasis (P=0.018, P=0.008, and P=0.039, respectively). Conclusions The prevalence of gastrointestinal tract bleeding in children with chronic cholestasis is 27.8%, with splenomegaly, thrombocytopenia, and esophageal varices as significant risk factors.
{"title":"Gastrointestinal tract bleeding in children with chronic cholestasis: Prevalence and risk factors in a tertiary referral hospital in Indonesia","authors":"F. Alatas, Cholifatun Nisa","doi":"10.14238/pi63.5.2023.370-5","DOIUrl":"https://doi.org/10.14238/pi63.5.2023.370-5","url":null,"abstract":"Background Cholestasis can lead to several complications, including portal hypertension and risk of gastrointestinal bleeding. However, there is a paucity of studies on the risk factors and prevalence of gastrointestinal tract bleeding in children with chronic cholestasis, particularly in Indonesia. Objective To determine the prevalence and risk factors for gastrointestinal bleeding in children with chronic cholestasis in Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Methods This was a retrospective cohort study in a national referral hospital in Indonesia. Medical records of children with chronic cholestasis who visited the gastroenterohepatology outpatient clinic were collected for five years. Data on clinical symptoms, etiologies, and complications were obtained. Results A total of 97 participants were recruited on this study. The median age of the group was 0.31 years old. The most common causes of chornic cholestasis were biliary atresia, toxoplasma, other infections, rubella, cytomegalovirus, and herpes simplex virus (TORCH) infection, and urinary tract infection. Gastrointestinal bleeding occurred in 27.8% of patients, with hematemesis-melena being the most prevalent symptom. We found that liver cirrhosis, splenomegaly, thrombocytopenia, portal hypertension, and esophageal varices were all highly related with gastrointestinal bleeding. Splenomegaly, thrombocytopenia, and esophageal varices were associated with an increased risk of gastrointestinal bleeding in children with chronic cholestasis (P=0.018, P=0.008, and P=0.039, respectively). Conclusions The prevalence of gastrointestinal tract bleeding in children with chronic cholestasis is 27.8%, with splenomegaly, thrombocytopenia, and esophageal varices as significant risk factors.","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":"23 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139315208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-28DOI: 10.14238/pi63.4.2023.304-14
Yaulia Yanrismet, E. Hidayati, Z. Munasir, Klara Yuliarti, Afifa Fahriyani
Background Henoch-Schönlein Purpura (HSP) is the most common systemic vasculitis disease in children. It is characterized by involvement of the skin, joints, gastrointestinal tract, and kidney. Kidney manifestations may progress to severe nephritis, even lead to end-stage kidney disease. Objective To identify the incidence and risk factors of nephritis in childhood HSP. Methods A retrospective cohort study was performed to evaluate clinical, demographic, laboratory, and therapeutic parameters of HSP patients aged 0-18 years between 2011-2019 at Dr. Cipto Mangunkusumo Hospital, Jakarta. Diagnoses of HSP were made according to the 2008 EULAR/PRES/PRINTO criteria. Wefollowed subjects’ medical records for at least 3 months after disease onset to observe incidence and risk factors of Henoch-Schönlein nephritis (HSN).Results There were 112 HSP patients (aged 2-17 years) included in this study. HSN was found in 40 out of 112 patients (35.7%). Nephritis developed within the first 4 weeks for a majority of cases. Multivariate analysis showed that persistent purpura (OR 3.306; 95%CI 1.315 to 8.315; P=0.011) and acute phase leukocytosis(OR 2.585; 95%CI 1.047 to 6.385; P=0.039) were significantly associated risk factors for HSN. We found that corticosteroid use did not reduce the risk of HSN. The accumulation of several risk factors was associated with the likelihood of developing HSN. Conclusion Persistent purpura and acute phase leukocytosis are independent risk factors for HSN. Therefore, blood tests are needed to estimate the risk of HSN. Early corticosteroid therapy do not reduce the risk of kidney impairment.
{"title":"Incidence and risk factors of nephritis in childhood Henoch-Schonlein purpura","authors":"Yaulia Yanrismet, E. Hidayati, Z. Munasir, Klara Yuliarti, Afifa Fahriyani","doi":"10.14238/pi63.4.2023.304-14","DOIUrl":"https://doi.org/10.14238/pi63.4.2023.304-14","url":null,"abstract":"Background Henoch-Schönlein Purpura (HSP) is the most common systemic vasculitis disease in children. It is characterized by involvement of the skin, joints, gastrointestinal tract, and kidney. Kidney manifestations may progress to severe nephritis, even lead to end-stage kidney disease. \u0000Objective To identify the incidence and risk factors of nephritis in childhood HSP. \u0000Methods A retrospective cohort study was performed to evaluate clinical, demographic, laboratory, and therapeutic parameters of HSP patients aged 0-18 years between 2011-2019 at Dr. Cipto Mangunkusumo Hospital, Jakarta. Diagnoses of HSP were made according to the 2008 EULAR/PRES/PRINTO criteria. Wefollowed subjects’ medical records for at least 3 months after disease onset to observe incidence and risk factors of Henoch-Schönlein nephritis (HSN).Results There were 112 HSP patients (aged 2-17 years) included in this study. HSN was found in 40 out of 112 patients (35.7%). Nephritis developed within the first 4 weeks for a majority of cases. Multivariate analysis showed that persistent purpura (OR 3.306; 95%CI 1.315 to 8.315; P=0.011) and acute phase leukocytosis(OR 2.585; 95%CI 1.047 to 6.385; P=0.039) were significantly associated risk factors for HSN. We found that corticosteroid use did not reduce the risk of HSN. The accumulation of several risk factors was associated with the likelihood of developing HSN. \u0000Conclusion Persistent purpura and acute phase leukocytosis are independent risk factors for HSN. Therefore, blood tests are needed to estimate the risk of HSN. Early corticosteroid therapy do not reduce the risk of kidney impairment.","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":"24 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78215429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-16DOI: 10.14238/pi63.4.2023.298-303
Sahara Effendy, S. Wandita, M. Julia
Background The global pandemic of severe acute respiratory syndrome caused by the coronavirus-2 (SARS-CoV-2) infection has resulted in a national large-scale social restriction (LSSR) to limit the spread of the virus. Objective To determine the impacts of LSSR on glycemic controls and the occurrence of complications in type-1 diabetes mellitus (T1DM) children. Methods A retrospective longitudinal study was carried out in Dr. Sardjito Hospital, Yogyakarta. Subjects were 0-18 years old T1DM patients diagnosed before the LSSR with at least six months of disease. Data on demographics, T1DM status, HbA1c level, and complications pre-LSSR, and during LSSR were taken from medical records. Paired T-tests were used to assess the difference in HbA1c level between the two-time points Results: We included information on 21 children based on the inclusion and exclusion criteria. Their median (range) age was 13.9 (1.42-17.3) years, with a median (range) diabetes duration of 2.6 (0.0-10.92) years. Glycemic control improved in 76% of the children. The mean HbA1c before and during LSSR was 10.9 (SD 2.7) and. 9.7 (SD 2.3), respectively; P<0.05. The glycemic control was not associated with sex, age, duration of diabetes, travel time to the clinic, or a total daily insulin dose. There was also no significant difference in the occurrence of complications. Conclusion Despite limitations during LSSR, glycemic control improved in most patients with T1DM. This might be related to improved health awareness during the pandemic, more regular meals, and better parental control.
{"title":"The effects of large-scale social restriction during the covid-19 pandemic on glycemic control and occurrence of complications in children with type-1 diabetes mellitus","authors":"Sahara Effendy, S. Wandita, M. Julia","doi":"10.14238/pi63.4.2023.298-303","DOIUrl":"https://doi.org/10.14238/pi63.4.2023.298-303","url":null,"abstract":"Background The global pandemic of severe acute respiratory syndrome caused by the coronavirus-2 (SARS-CoV-2) infection has resulted in a national large-scale social restriction (LSSR) to limit the spread of the virus. \u0000Objective To determine the impacts of LSSR on glycemic controls and the occurrence of complications in type-1 diabetes mellitus (T1DM) children. \u0000Methods A retrospective longitudinal study was carried out in Dr. Sardjito Hospital, Yogyakarta. Subjects were 0-18 years old T1DM patients diagnosed before the LSSR with at least six months of disease. Data on demographics, T1DM status, HbA1c level, and complications pre-LSSR, and during LSSR were taken from medical records. Paired T-tests were used to assess the difference in HbA1c level between the two-time points \u0000Results: We included information on 21 children based on the inclusion and exclusion criteria. Their median (range) age was 13.9 (1.42-17.3) years, with a median (range) diabetes duration of 2.6 (0.0-10.92) years. Glycemic control improved in 76% of the children. The mean HbA1c before and during LSSR was 10.9 (SD 2.7) and. 9.7 (SD 2.3), respectively; P<0.05. The glycemic control was not associated with sex, age, duration of diabetes, travel time to the clinic, or a total daily insulin dose. There was also no significant difference in the occurrence of complications. \u0000Conclusion Despite limitations during LSSR, glycemic control improved in most patients with T1DM. This might be related to improved health awareness during the pandemic, more regular meals, and better parental control. ","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":"16 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89828583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-16DOI: 10.14238/pi63.4.2023.315-20
Dikahayu Alifia Anugrah, Sunartini Sunartini, Mohammad Juffrie
Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease that causes general weakness, muscle atrophy, and poor muscle movement. This condition is due to a homozygous disruption of the survival motor neuron (SMN) 1 survival gene due to deletion, conversion, or mutation.1
{"title":"Spinal muscular atrophy with severe scoliosis: a case report","authors":"Dikahayu Alifia Anugrah, Sunartini Sunartini, Mohammad Juffrie","doi":"10.14238/pi63.4.2023.315-20","DOIUrl":"https://doi.org/10.14238/pi63.4.2023.315-20","url":null,"abstract":"Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease that causes general weakness, muscle atrophy, and poor muscle movement. This condition is due to a homozygous disruption of the survival motor neuron (SMN) 1 survival gene due to deletion, conversion, or mutation.1","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":"129 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79578699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-15DOI: 10.14238/pi63.4.2023.290-7
Whyra Pratama Said, K. Arto, W. Pratita, Sufitni Sufitni
Background Congenital hypothyroidism (CH) is the most common congenital endocrine disorder in childhood and is one of the most preventable causes of intellectual disability (ID). Late initiation of thyroid hormone substitution therapy has a negative impact on intellectual abilities in CH patients. Objective To compare Intelligence Quotient (IQ) between children with CH who underwent early treatment among the children without CH. Methods We performed online literature searches of ScienceDirect, Pubmed, Cochrane Library, and Google Scholar. We included clinical studies that examined IQ scores in patients with early-treated CH and without CH. Review Manager 5.4 was used to perform the meta-analysis. Results Twelve studies comparing pediatric patients with and without CH were included in this meta-analysis, for a total of 808 patients. Based on data analysis, IQ levels of verbal IQ [mean difference (MD) -9.05; (95%CI -14.51 to -3.59); (P<0.00001)], performance IQ [MD -11.70; (95%CI -17.41 to -5.99); (P<0.00001)], and total IQ [MD -10.78; (95%CI -14.03 to -7.54); (P<0.00001)]. While verbal, performance, total, of the early-treated CH group were within the normal range, they were each significantly lower than those in the non-CH group. Conclusion This meta-analysis reveals that IQ scores in early-treated CH subjects were within normal limits, but significantly lower than that of normal controls.
{"title":"Intelligence quotient (IQ) outcome in children with early-treated congenital hypothyroidism: a systematic review and meta-analysis","authors":"Whyra Pratama Said, K. Arto, W. Pratita, Sufitni Sufitni","doi":"10.14238/pi63.4.2023.290-7","DOIUrl":"https://doi.org/10.14238/pi63.4.2023.290-7","url":null,"abstract":"Background Congenital hypothyroidism (CH) is the most common congenital endocrine disorder in childhood and is one of the most preventable causes of intellectual disability (ID). Late initiation of thyroid hormone substitution therapy has a negative impact on intellectual abilities in CH patients. \u0000Objective To compare Intelligence Quotient (IQ) between children with CH who underwent early treatment among the children without CH. \u0000Methods We performed online literature searches of ScienceDirect, Pubmed, Cochrane Library, and Google Scholar. We included clinical studies that examined IQ scores in patients with early-treated CH and without CH. Review Manager 5.4 was used to perform the meta-analysis. \u0000Results Twelve studies comparing pediatric patients with and without CH were included in this meta-analysis, for a total of 808 patients. Based on data analysis, IQ levels of verbal IQ [mean difference (MD) -9.05; (95%CI -14.51 to -3.59); (P<0.00001)], performance IQ [MD -11.70; (95%CI -17.41 to -5.99); (P<0.00001)], and total IQ [MD -10.78; (95%CI -14.03 to -7.54); (P<0.00001)]. While verbal, performance, total, of the early-treated CH group were within the normal range, they were each significantly lower than those in the non-CH group. \u0000Conclusion This meta-analysis reveals that IQ scores in early-treated CH subjects were within normal limits, but significantly lower than that of normal controls.","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":"62 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88141694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background Parents usually make the decisions on COVID-19 vaccinations for their children under the age of 18. Objective To explore parents' perceptions and expectations of COVID-19 vaccination for children in Banda Aceh. Methods This study used a qualitative design with a phenomenological approach. Data were collected through in-depth interviews of 36 parents in Banda Aceh. The data were analyzed qualitatively through thematic analysis. Results Three themes were studied: (1) perceptions of parents willing to have their children vaccinated against COVID-19, (2) perceptions of parents who refused or delayed their children’s vaccination against COVID-19, and (3) parents' expectations regarding COVID-19 vaccination in children. Benefits of the vaccine and government policy were among the reasons that parents were willing to have their children vaccinated. Vaccine safety concerns, lack of information, strong immunity, healthy lifestyle, and religious beliefs were the main reasons for parental refusal or delay in vaccinating their children. Reduced cases of COVID-19 and the end of the pandemic, not being infected, developing immunity, and no adverse events following immunization, face-to-face learning in schools, as well as increased education and socialization from the government, society that was critical and selective in receiving information were the expectation of parents regarding COVID-19 vaccination in children. Conclusion The perception of vaccine benefits and government policy influence parents to have their children vaccinated, while perception of vaccine safety concerns, lack of information, strong immunity, healthy lifestyle, and religious beliefs influence parents to refuse or delay their children being vaccinated. Parents' expectations regarding COVID-19 illness, their children’s response to the vaccine and education, as well as the government’s and society’s roles during the pandemic are qualitatively elucidated.
{"title":"Parents’ perceptions and expectations of COVID-19 vaccination for children in Banda Aceh","authors":"Teuku Ade Prasetia, Bakhtiar Bakhtiar, Heru Noviat Herdata, Nora Sovira, Anidar Anidar, Eka Yunita Amna, Syafruddin Haris","doi":"10.14238/pi63.4.2023.256-66","DOIUrl":"https://doi.org/10.14238/pi63.4.2023.256-66","url":null,"abstract":"Background Parents usually make the decisions on COVID-19 vaccinations for their children under the age of 18. \u0000Objective To explore parents' perceptions and expectations of COVID-19 vaccination for children in Banda Aceh. \u0000Methods This study used a qualitative design with a phenomenological approach. Data were collected through in-depth interviews of 36 parents in Banda Aceh. The data were analyzed qualitatively through thematic analysis. \u0000Results Three themes were studied: (1) perceptions of parents willing to have their children vaccinated against COVID-19, (2) perceptions of parents who refused or delayed their children’s vaccination against COVID-19, and (3) parents' expectations regarding COVID-19 vaccination in children. Benefits of the vaccine and government policy were among the reasons that parents were willing to have their children vaccinated. Vaccine safety concerns, lack of information, strong immunity, healthy lifestyle, and religious beliefs were the main reasons for parental refusal or delay in vaccinating their children. Reduced cases of COVID-19 and the end of the pandemic, not being infected, developing immunity, and no adverse events following immunization, face-to-face learning in schools, as well as increased education and socialization from the government, society that was critical and selective in receiving information were the expectation of parents regarding COVID-19 vaccination in children. \u0000Conclusion The perception of vaccine benefits and government policy influence parents to have their children vaccinated, while perception of vaccine safety concerns, lack of information, strong immunity, healthy lifestyle, and religious beliefs influence parents to refuse or delay their children being vaccinated. Parents' expectations regarding COVID-19 illness, their children’s response to the vaccine and education, as well as the government’s and society’s roles during the pandemic are qualitatively elucidated.","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":"55 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77280445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-14DOI: 10.14238/pi63.4.2023.267-73
Dr Rahmawati
Background : Prevalence of congenital heart disease is approximately 8/1000 live births and majority of them are diagnosed during evaluation of a murmur detected either during a routine follow-up or while assessment during an intercurrent illness. NADAS criteria can be used as screening test with hight a sensitivity and specificity regarding ability to differentiate pathologic from innocent murmurs. Aim : The aim of the study was to assess the accuracy of the NADAS criteria in helping to diagnose disease in children suspected of having congenital heart disease. Methods : This was a diagnostic study with a cross-sectional approach and Inclusion criteria were children aged 1 month - 12 years from history and physical examination found a history of recurrent ARI, poor nutritional status, failure to thrive, found cardiac murmurs, without/any cyanosis who attended the outpatient cardiology pediatric at Haji Adam Malik General Hospital between Januari - july 2021. Data Analysis was created using the program IBM SPSS Statistics version 25 Results : 70 children were screened. 60 children were detected to have CHD. 63,3% of the study population in the age group <5 year had a heart disease. All CHD patients had poor nutritional status, abnormal ECG and 88.33% had a history of recurrent ARI, 80% had abnormal chest x-ray, and 55% had abnormal S2. A grade 3 or higher systolic murmur was found in 78.33% of patients had CHD. Conclusion : NADAS criteria can be used as a screening test for helping to diagnose disease in children suspected of having CHD with accuracy 87.14%, sensitivity of 88.33%, specificity was 80% when score at 3 (1 major + 2 minor) and AUC value is 0.842.
背景:先天性心脏病的患病率约为8/1000活产婴儿，其中大多数是在常规随访或在合并疾病期间评估时检测到的杂音时诊断出来的。NADAS标准可作为筛选试验，在区分病理性和无害性杂音的能力方面具有较高的敏感性和特异性。目的:本研究的目的是评估NADAS标准在帮助诊断怀疑患有先天性心脏病的儿童疾病方面的准确性。方法:这是一项采用横断面方法的诊断性研究，纳入标准是年龄为1个月至12岁的儿童，从病史和体格检查中发现复发性ARI病史，营养状况不佳，发育不良，发现心脏杂音，没有/任何紫绀，这些儿童在2021年1月至7月期间在Haji Adam Malik综合医院的儿科心脏病门诊就诊。使用IBM SPSS Statistics version 25进行数据分析。结果:筛选了70名儿童。60名儿童被检出冠心病。在5岁以下的研究人群中，63.3%的人患有心脏病。所有冠心病患者营养状况不佳，心电图异常，88.33%有ARI复发史，80%胸片异常，55% S2异常。78.33%的冠心病患者有3级及以上的收缩期杂音。结论:NADAS标准可作为一种有助于诊断疑似冠心病儿童疾病的筛查试验，其准确性为87.14%，敏感性为88.33%，特异性为80%，评分为3分(1主要+ 2次要)，AUC值为0.842。
{"title":"Accuracy of the NADAS Criteria in Helping Establish the Diagnosis in Children With Suspected to Have Congenital Heart Disease","authors":"Dr Rahmawati","doi":"10.14238/pi63.4.2023.267-73","DOIUrl":"https://doi.org/10.14238/pi63.4.2023.267-73","url":null,"abstract":"Background : Prevalence of congenital heart disease is approximately 8/1000 live births and majority of them are diagnosed during evaluation of a murmur detected either during a routine follow-up or while assessment during an intercurrent illness. NADAS criteria can be used as screening test with hight a sensitivity and specificity regarding ability to differentiate pathologic from innocent murmurs. \u0000Aim : The aim of the study was to assess the accuracy of the NADAS criteria in helping to diagnose disease in children suspected of having congenital heart disease. \u0000Methods : This was a diagnostic study with a cross-sectional approach and Inclusion criteria were children aged 1 month - 12 years from history and physical examination found a history of recurrent ARI, poor nutritional status, failure to thrive, found cardiac murmurs, without/any cyanosis who attended the outpatient cardiology pediatric at Haji Adam Malik General Hospital between Januari - july 2021. Data Analysis was created using the program IBM SPSS Statistics version 25 \u0000Results : 70 children were screened. 60 children were detected to have CHD. 63,3% of the study population in the age group <5 year had a heart disease. All CHD patients had poor nutritional status, abnormal ECG and 88.33% had a history of recurrent ARI, 80% had abnormal chest x-ray, and 55% had abnormal S2. A grade 3 or higher systolic murmur was found in 78.33% of patients had CHD. \u0000Conclusion : NADAS criteria can be used as a screening test for helping to diagnose disease in children suspected of having CHD with accuracy 87.14%, sensitivity of 88.33%, specificity was 80% when score at 3 (1 major + 2 minor) and AUC value is 0.842.","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":"101 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73058541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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